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Littérature scientifique sur le sujet « EOB Model »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 11 mars 2023

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Articles de revues sur le sujet "EOB Model"

Debona, Daniel, Angela Pivotto, Alexsandro J. Tetzlaff, Darlan F. Sartori, Luiz A. Borelli, Murilo S. de Oliveira, Lilian Y. Yamamoto et Jociani Ascari. « Essential Oil of Baccharis dracunculifolia (Asteraceae) Decreases Alternaria Rot in Pitahaya ». Journal of Agricultural Science 13, n^o 7 (15 juin 2021) : 10. http://dx.doi.org/10.5539/jas.v13n7p10.

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Alternaria rot, caused by Alternaria alternata, is one of the most destructive diseases of pitahaya (Hylocereus spp.). We investigated the effect of the essential oil of Baccharis dracunculifolia (Asteraceae) (EOB) in the control of A. alternata. Two studies were performed in Petri dishes containing potato dextrose agar medium amended with concentrations of the EOB ranging from 5 to 1,000 µg mL-1 (first study) and from 30 to 2,000 µg mL-1. The diameter of the fungal colony was recorded daily. These data were used to calculate the the area under the mycelial growth progress curve (AUMGPC) and mycelial growth index (MGI). In the third study, the control of Alternaria rot in pitahaya fruits by EOB was investigated by adding the EOB into an edible coat based on cassava starch and sorbitol which was prepared in Tween 20. Three treatments, containing EOB at 500, 1,000 or 2,000 µg mL-1, were assessed. Two additional treatments, one containing water and another containing only the edible coating served as controls. Pitahaya fruits were immersed in those solutions for 10 min, allowed to dry and inoculated with A. alternata 48 h later. The EOB was found to inhibit the mycelial growth and a negative and quadratic model best described the relationship of the EOB concentrations with MGI and AUMGPC. Results from the experiment performed with pitahaya fruits showed that Alternaria rot was decreased with increasing EOB concentrations. Therefore, EOB is a promising and ecofriendly method that may be included in the management of Alternaria rot in pitahya.

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Vicka, Vaidas, Elija Januskeviciute, Justina Krauklyte, Aiste Aleknaviciene, Donata Ringaitiene, Ligita Jancoriene et Jurate Sipylaite. « Determinants of Increased Effort of Breathing in Non-Intubated Critical COVID-19 Patients ». Medicina 58, n^o 8 (21 août 2022) : 1133. http://dx.doi.org/10.3390/medicina58081133.

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Background and objectives: Acute respiratory distress syndrome (ARDS) is the most common complication occurring in COVID-19 patients admitted to the ICU. Given the increased respiratory work of these patients, it is necessary to evaluate their actual breathing efforts. The aim of this study is to report the incidence and determinants of increased effort of breathing (EOB) in critical COVID-19 patients. Materials and Methods: This was a retrospective study of COVID-19 patients admitted to the ICU during the year of 2020. Respiratory rate (RR) was chosen as an indicator of EOB. The cut-off value was set at more than 20 breaths per minute. ROC-AUC analysis was performed to identify the accuracy of the PaO2 and PaCO2 to determine increased EOB. Furthermore, multivariate regression analysis was performed to reveal the determinants of increased EOB. Results: 213 patients were included in the study. Mean RR in the population was 24.20 ± 6.28. 138 (64.8%) of the patients had increased EOB. The ROC-AUC analysis revealed the PaO2 (0.656 (CI 95%: 0.579–0.734, p < 0.001) as more accurate predictor of EOB than PaCO2 (0.584 (CI 95%: 0.505–0.662, p = 0.043). In the final multivariate model, the SpO2 (exp(B) = 0.922, CI 95%: 0.874–0.97 p = 0.033), PaO2/FiO2 ratio (exp(B) = 0.996, CI 95%: 0.922–1.000, p = 0.003) and PaO2 (exp(B) = 0.989 CI 95%: 0.982–0.996 p = 0.003) prevailed as independent predictors of increased EOB. Conclusions: To conclude, PaO2 was revealed as a more accurate predictor of increased EOB than PaCO2. Further investigation revealed the independent determinants of EOB: blood oxygen saturation, PaO2 and PaO2/FiO2 ratio.

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Wei, Jingwei, Hanyu Jiang, Mengsu Zeng, Meiyun Wang, Meng Niu, Dongsheng Gu, Huanhuan Chong et al. « Prediction of Microvascular Invasion in Hepatocellular Carcinoma via Deep Learning : A Multi-Center and Prospective Validation Study ». Cancers 13, n^o 10 (14 mai 2021) : 2368. http://dx.doi.org/10.3390/cancers13102368.

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Microvascular invasion (MVI) is a critical risk factor for postoperative recurrence of hepatocellular carcinoma (HCC). Preknowledge of MVI would assist tailored surgery planning in HCC management. In this multicenter study, we aimed to explore the validity of deep learning (DL) in MVI prediction using two imaging modalities—contrast-enhanced computed tomography (CE-CT) and gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI). A total of 750 HCCs were enrolled from five Chinese tertiary hospitals. Retrospective CE-CT (n = 306, collected between March, 2013 and July, 2019) and EOB-MRI (n = 329, collected between March, 2012 and March, 2019) data were used to train two DL models, respectively. Prospective external validation (n = 115, collected between July, 2015 and February, 2018) was performed to assess the developed models. Furthermore, DL-based attention maps were utilized to visualize high-risk MVI regions. Our findings revealed that the EOB-MRI-based DL model achieved superior prediction outcome to the CE-CT-based DL model (area under receiver operating characteristics curve (AUC): 0.812 vs. 0.736, p = 0.038; sensitivity: 70.4% vs. 57.4%, p = 0.015; specificity: 80.3% vs. 86.9%, p = 0.052). DL attention maps could visualize peritumoral high-risk areas with genuine histopathologic confirmation. Both DL models could stratify high and low-risk groups regarding progression free survival and overall survival (p < 0.05). Thus, DL can be an efficient tool for MVI prediction, and EOB-MRI was proven to be the modality with advantage for MVI assessment than CE-CT.

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Fehrenbach, Uli, Siyi Xin, Alexander Hartenstein, Timo Alexander Auer, Franziska Dräger, Konrad Froböse, Henning Jann et al. « Automatized Hepatic Tumor Volume Analysis of Neuroendocrine Liver Metastases by Gd-EOB MRI—A Deep-Learning Model to Support Multidisciplinary Cancer Conference Decision-Making ». Cancers 13, n^o 11 (31 mai 2021) : 2726. http://dx.doi.org/10.3390/cancers13112726.

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Background: Rapid quantification of liver metastasis for diagnosis and follow-up is an unmet medical need in patients with secondary liver malignancies. We present a 3D-quantification model of neuroendocrine liver metastases (NELM) using gadoxetic-acid (Gd-EOB)-enhanced MRI as a useful tool for multidisciplinary cancer conferences (MCC). Methods: Manual 3D-segmentations of NELM and livers (149 patients in 278 Gd-EOB MRI scans) were used to train a neural network (U-Net architecture). Clinical usefulness was evaluated in another 33 patients who were discussed in our MCC and received a Gd-EOB MRI both at baseline and follow-up examination (n = 66) over 12 months. Model measurements (NELM volume; hepatic tumor load (HTL)) with corresponding absolute (ΔabsNELM; ΔabsHTL) and relative changes (ΔrelNELM; ΔrelHTL) between baseline and follow-up were compared to MCC decisions (therapy success/failure). Results: Internal validation of the model’s accuracy showed a high overlap for NELM and livers (Matthew’s correlation coefficient (φ): 0.76/0.95, respectively) with higher φ in larger NELM volume (φ = 0.80 vs. 0.71; p = 0.003). External validation confirmed the high accuracy for NELM (φ = 0.86) and livers (φ = 0.96). MCC decisions were significantly differentiated by all response variables (ΔabsNELM; ΔabsHTL; ΔrelNELM; ΔrelHTL) (p < 0.001). ΔrelNELM and ΔrelHTL showed optimal discrimination between therapy success or failure (AUC: 1.000; p < 0.001). Conclusion: The model shows high accuracy in 3D-quantification of NELM and HTL in Gd-EOB-MRI. The model’s measurements correlated well with MCC’s evaluation of therapeutic response.

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You, Myung-Won, Hyoung Jung Kim, Hyeong-Seok Lim, So Yeon Kim, Jae Ho Byun, Kyung Won Kim, Dae Wook Hwang et Young-Joo Lee. « Assessment of Liver Function Using Pharmacokinetic Parameters of Gd-EOB-DTPA : Experimental Study in Rat Hepatectomy Model ». Contrast Media & ; Molecular Imaging 2018 (2018) : 1–7. http://dx.doi.org/10.1155/2018/6321316.

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Objectives. To determine whether the pharmacokinetic parameters of Gd-EOB-DTPA can identify the difference in liver function in a rat hepatectomy model. Methods. A total of 56 eight-week-old male Sprague-Dawley rats were divided into the following groups: control group without hepatectomy (n=16), 70% hepatectomy group (n=14), and 90% hepatectomy group (n=26). On postoperative day 2, Gd-EOB-DTPA (0.1 mmol/kg) was injected intravenously and serial blood samples were obtained. Pharmacokinetic analysis was performed using a noncompartmental method. Statistical analysis was performed using one-way analysis of variance and post hoc pairwise group comparisons. Results. After excluding 6 rats that died unexpectedly, blood samples were obtained from 16, 14, and 20 rats in the control group, 70% hepatectomy group, and 90% hepatectomy group. There was a significant increase in area under the concentration-time curve from time zero to the time of the last measurable concentration between the 70% and 90% hepatectomy group (P<0.001). The volume of distribution at steady state was significantly decreased between the control and 70% hepatectomy group (P<0.001). The clearance was significantly different in all pairwise group comparisons (P<0.001). Conclusions. The vascular clearance of Gd-EOB-DTPA can identify the difference in liver function in a rat hepatectomy model.

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Tanpowpong, Natthaporn, et Teerasak Phewplung. « Brief communication (Original). Correlation between liver signal intensity in hepatobiliary phase of Gd-EOB-DTPA enhancement and liver function reserves ». Asian Biomedicine 8, n^o 3 (1 juin 2014) : 411–15. http://dx.doi.org/10.5372/1905-7415.0803.308.

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Abstract Background: Gadolinium diethylenetriamine-pentaacetic acid (Gd-EOB-DTPA) is a developed agent with preferential uptake by hepatocytes. A rapid and specific hepatocyte uptake with biliary excretion was observed of approximately 50% of the injected dose. The amount of contrast uptake is thought to be related to reserve liver function. Objectives: To evaluate correlation between liver signal intensity in the hepatobiliary phase of Gd-EOB-DTPA and reserved liver function by using the model score for end-stage liver disease (MELD). Methods:All patients who underwent magnetic resonance (MR) imaging with Gd-EOB-DTPA were retrospectively collected. The patients with serum creatinine level higher than 1.5 mg/dL or patients without available data to estimate MELD score were excluded. Thirty-six patients were enrolled. A signal-to-noise ratio (SNR) in the liver parenchyma on a fat-suppressed three dimensional fast spoiled-gradient recalled echo sequence images before and 20 minutes after contrast injection were measured and calculated on PACS by two radiologists. The MELD score was determined and interobserver reliability was estimated. Results: Among 36 patients, we found a negative relationship between the percentage enhancement and the MELD score (P < 0.01, r = 0.545). The SNR at 20 minutes after Gd-EOB-DTPA injection also had a negative relationship with the MELD score with statistical significance (P < 0.01, r = 0.460). Interobserver reliability was 0.675. Conclusion: The percentage enhancement in hepatobiliary phase of Gd-EOB-DTPA can predict reserved liver function.

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Huang, Mengqi, Bing Liao, Ping Xu, Huasong Cai, Kun Huang, Zhi Dong, Ling Xu et al. « Prediction of Microvascular Invasion in Hepatocellular Carcinoma : Preoperative Gd-EOB-DTPA-Dynamic Enhanced MRI and Histopathological Correlation ». Contrast Media & ; Molecular Imaging 2018 (2018) : 1–9. http://dx.doi.org/10.1155/2018/9674565.

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Objective. To investigate the imaging features observed in preoperative Gd-EOB-DTPA-dynamic enhanced MRI and correlated with the presence of microvascular invasion (MVI) in hepatocellular carcinoma (HCC) patients. Methods. 66 HCCs in 60 patients with preoperative Gd-EOB-DTPA-dynamic enhanced MRI were retrospectively analyzed. Features including tumor size, signal homogeneity, tumor capsule, tumor margin, peritumor enhancement during mid-arterial phase, peritumor hypointensity during hepatobiliary phase, signal intensity ratio on DWI and apparent diffusion coefficients (ADC), T1 relaxation times, and the reduction rate between pre- and postcontrast enhancement images were assessed. Correlation between these features and histopathological presence of MVI was analyzed to establish a prediction model. Results. Histopathology confirmed that MVI were observed in 17 of 66 HCCs. Univariate analysis showed tumor size (p=0.003), margin (p=0.013), peritumor enhancement (p=0.001), and hypointensity during hepatobiliary phase (p=0.004) were associated with MVI. A multiple logistic regression model was established, which showed tumor size, margin, and peritumor enhancement were combined predictors for the presence of MVI (α=0.1). R2 of this prediction model was 0.353, and the sensitivity and specificity were 52.9% and 93.0%, respectively. Conclusion. Large tumor size, irregular tumor margin, and peritumor enhancement in preoperative Gd-EOB-DTPA-dynamic enhanced MRI can predict the presence of MVI in HCC.

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Lee, Yi-Hsueh, Menq-Rong Wu et Jong-Kai Hsiao. « Organic Anion Transporting Polypeptide 1B1 Is a Potential Reporter for Dual MR and Optical Imaging ». International Journal of Molecular Sciences 22, n^o 16 (16 août 2021) : 8797. http://dx.doi.org/10.3390/ijms22168797.

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Membrane proteins responsible for transporting magnetic resonance (MR) and fluorescent contrast agents are of particular importance because they are potential reporter proteins in noninvasive molecular imaging. Gadobenate dimeglumine (Gd-BOPTA), a liver-specific MR contrast agent, has been used globally for more than 10 years. However, the corresponding molecular transportation mechanism has not been validated. We previously reported that the organic anion transporting polypeptide (OATP) 1B3 has an uptake capability for both MR agents (Gd-EOB-DTPA) and indocyanine green (ICG), a clinically available near-infrared (NIR) fluorescent dye. This study further evaluated OATP1B1, another polypeptide of the OATP family, to determine its reporter capability. In the OATP1B1 transfected 293T transient expression model, both Gd-BOPTA and Gd-EOB-DTPA uptake were confirmed through 1.5 T MR imaging. In the constant OAPT1B1 and OATP1B3 expression model in the HT-1080 cell line, both HT-1080-OAPT1B1 and HT-1080-OATP1B3 were observed to ingest Gd-BOPTA and Gd-EOB-DTPA. Lastly, we validated the ICG uptake capability of both OATP1B1 and OATP1B3. OAPT1B3 exhibited a superior ICG uptake capability to that of OAPT1B1. We conclude that OATP1B1 is a potential reporter for dual MR and NIR fluorescent molecular imaging, especially in conjunction with Gd-BOPTA.

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Bilton, Shawna, et Zhi Sheng. « DDDR-12. THE ROLE OF CASEIN KINASE 1 EPSILON IN TEMOZOLOMIDE SENSITIVITY IN GLIOBLASTOMA STEM CELLS ». Neuro-Oncology 24, Supplement_7 (1 novembre 2022) : vii101. http://dx.doi.org/10.1093/neuonc/noac209.377.

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Abstract A major hurdle in effectively treating glioblastoma is the resistance to current chemotherapy temozolomide (TMZ), exhibited intrinsically in glioblastoma stem cells (GSCs). GSCs are a population of tumor cells that are self-renewing, highly resilient and capable of forming genetically heterogeneous and difficult-to-treat tumors. Therefore, overcoming TMZ resistance holds significant promise in the treatment of glioblastoma. Casein kinase 1 ε (CK1ε) has been identified as a stem cell factor that is important for GSCs to self-renew. However, whether CK1ε confers TMZ resistance in GSCs remains elusive. METHODS To test the role of CK1ε in the chemoresistance of GSCs, we treated GSC adherent cell lines with TMZ, CK1ε inhibitor IC261, and a combination of TMZ plus IC261. Cell viability was assessed with MTS viability assay or CellTiter-Blue viability assay. RESULTS Cell viability was significantly decreased in GSCs treated with 0.8μM IC261 combined with 100μM TMZ as compared to cells treated with either 0.8μM IC261 or 100μM TMZ alone (p < 0.05). We assessed synergistic drug effects using the Bliss independence model to yield Excess Over Bliss (EOB) scores. EOB > 0% indicates a synergistic effect; EOB = 0% indicates additive effect; and EOB < 0% indicates antagonistic effect. Cells treated with 0.8μM IC261 together with 100μM TMZ yielded EOB of > 0%. CONCLUSIONS Previous work has identified CK1ε as an important stem cell factor in the survival GSCs, but there lacked studies testing the role of CK1ε in TMZ chemoresistance in vitro. We demonstrate synergistic inhibition of cell viability in GSCs treated with CK1ε inhibitor IC261 in combination with TMZ. Based on these results, CK1ε is suggested to play an important role in the chemoresistance of GSCs to TMZ.

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Mattson, J. K., A. T. DeVries, S. M. McGuire, J. Krebs, E. E. Louis et N. M. Loskutoff. « 247 SUCCESSFUL ARTIFICIAL INSEMINATION IN THE CORN SNAKE (ELAPHE GUTATTA), USING FRESH AND COOLED SEMEN ». Reproduction, Fertility and Development 19, n^o 1 (2007) : 240. http://dx.doi.org/10.1071/rdv19n1ab247.

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The purpose of this investigation was to develop a non-invasive technique to artificially inseminate snakes using the corn snake, Elaphe gutatta, as the model representative for this taxon. Semen was collected by first applying pressure to the lower abdomen in a continuous distal motion toward the cloaca to remove any feces or urates. The cloaca was then gently washed using phosphate-buffered saline, and a more localized pressure was applied to each side of the vent to evert the hemipenes and, subsequently, the ejaculate. The semen was collected using a sterile transfer pipette and placed into 70 to 90 �L of medium (TL-HEPES solution; Cambrex Bio Science, Inc., Baltimore, MD, USA04–616F) in a sterile microcentrifuge tube, and then analyzed for overall motility, rate of forward progression (RFP, 0–5), and concentration. Based on a previously reported procedure, 10 females were inseminated with either fresh (n = 5) or cooled semen (n = 5; refrigerated for 3 days) one week after recovering from a hibernation period required to stimulate reproduction in this species. The overall sperm motility and concentration for females inseminated with fresh or cooled semen was 92%, 9.6 million sperm mL-1; and 85%, 6.1 million sperm mL-1, respectively. Immediately prior to insemination, the same method for expressing feces and urates in the males was applied to the females. The insemination dose (50 �L semen per oviduct) was drawn into a 1-mL latex- and silicone-free tuberculin syringe (Norm-Ject; VWR, Batavia, IL, USA) that was connected to a feeding/dosing needle (EJAY International, Issaquah, WA, USA) with a ball tip to prevent any potential damage during the insemination. The tip of the needle was then moved around the inner tissue of the vent to relax the cloaca, and the insertion continued until resistance was found indicating the vicinity of the oviducts. The extended semen was carefully deposited on both sides, and then the needle was slowly withdrawn. The offspring were tested for parentage to verify the success of the insemination. Blood was collected from the dorsal aorta posterior to the cloaca and stored in 10 mM Tris at 4�C. The DNA was extracted using a phenyl : chloroform : isoamyl alcohol (PCI) extraction method. Eight microsatellite loci were used for the paternity exclusion analysis: Eob�1, Eob�3, Eob�10, Eob�13, Eob�16, Eob�34, Eob�366, and Eob�373 (IDT, Coraville, IA, USA). All males and females in the collection were tested, and parental candidates were excluded if 2 or more allele mismatches occurred. From the total number of females inseminated, 3 females laid 51 eggs. Two females inseminated with cooled semen laid 36 eggs, of which 5 eggs were hatched, and the remaining were either unfertilized (n = 25) or non-viable (n = 6). All 5 hatched eggs were laid by one of the females. The third female inseminated with fresh semen laid 15 eggs, resulting in 5 hatching and 10 unfertilized eggs. The parentage test validated the AI a success as the alleles correlated between the adults and the offspring. In conclusion, artificial insemination was successful using both freshly collected and cooled (3 days) semen. Further studies are underway to improve the success rate in order to maximize the efficiency of this technology, and thus assist in the genetic preservation of endangered snake species.

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Thèses sur le sujet "EOB Model"

Samuelsson, Johanna. « Visualization of Regional Liver Function with Hepatobiliary Contrast Agent Gd-EOB-DTPA ». Thesis, Linköpings universitet, Institutionen för medicin och hälsa, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-71121.

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Liver biopsy is a very common, but invasive procedure for diagnosing liver disease. However, such a biopsy may result in severe complications and in some cases even death. Therefore, it would be highly desirable to develop a non-invasive method which would provide the same amount of information on staging of the disease and also the location of pathologies. This thesis describes the implementation of such a non-invasive method for visualizing and quantifying liver function by the combination of MRI (Magnetic Resonance Imaging), image reconstruction, and image analysis, and pharmacokinetic modeling. The first attempt involved automatic segmentation, functional clustering (k-means) and classification (kNN) of in-data (liver, spleen and blood vessel segments) in the pharmacokinetic model. However, after implementing and analyzing this method some important issues were identified and the image segmentation method was therefore revised. The segmentation method that was subsequently developed involved a semi-automatic procedure, based on a modified image forest transform (IFT). The data were then simulated and optimized using a pharmacokinetic model describing the pharmacokinetics of the liver specific contrast agent Gd-EOB-DTPA in the human body. The output from the modeling procedure was then further analyzed, using a least-squares method, in order to assess liver function by estimating the fractions of hepatocytes, extracellular extravascular space (EES) and blood plasma in each voxel of the image. The result were in fair agreement with literature values, although further analyses and developments will be required in order to validate and also to confirm the accuracy of the method.

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MESSINA, FRANCESCO. « IMPROVING THE EOB TOOLBOX FOR GRAVITATIONAL WAVE DATA ANALYSIS ». Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/299793.

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La stima dei parametri fisici degli eventi di onde gravitazionali rilevati da LIGO e Virgo si basa su modelli di forme d'onda analitiche, eventualmente calibrati da simulazioni di Relatività Numerica. Il modello EOB (Effective-One-Body) è uno dei principali modelli analitici per l’analisi dei segnali gravitazionali emessi da buchi neri e stelle di neutroni. La qui presente tesi, a grandi linee, è un lavoro di “potenziamento” di questo modello, e in particolare I) lo miglioriamo nei suoi vari settori, con l'obiettivo finale di costruire un modello che includa tutte le informazioni fisiche disponibili: in particolare, quelle riguardanti i multipoli subdominanti, utili per ottimizzare la risoluzione angolare dell'analisi dati degli esperimenti di onde gravitazionali [ 1, 4, 5, 7]; II) usarlo per sviluppare approssimanti Post-Newtoniani veloci, di ordine elevato, molto utili per le analisi bayesiane inerenti le pipeline LIGO e Virgo [3]; III) utilizzarlo per studiare, nel caso delle stelle binarie di neutroni, l’influenza degli effetti di self-spin sulla loro forma d'onda [2]. Uno degli elementi costitutivi centrali del modello EOB è la forma d'onda multipolare Post-Newtoniana (PN) fattorizzata e circolarizzata introdotta in [8] per binarie senza spin. In[4], estendiamo fino a l= 6 (cioè a multipoli alti) l'approccio di Nagar e Shah [9], poiché ha un accordo con la relatività numerica (utilizzata come punto di riferimento per la calibrazione) migliore del suo precursore [8]. In [4], questo approccio è stato aggiornato al caso di una particella rotante intorno ad un buco nero di Schwartzschild. Lo stesso approccio è stato altresì adattato in [5] al fine di aggiornare il modello EOB quadrupolare TEOBResumS, un codice C ++ [1] disponibile nella LIGO Advanced Library (LAL) e citato nel catalogo [10], a una sua naturale versione multipolare [7]. Fatto salvo ciò, mediante la tecnica di espansione EOB-PN definita in [11], il lavoro svolto in [3] conduce a un approssimante fenomenologico di ordine 5.5PN veloce e preciso che, includendo più informazioni sulle correzioni test-particle rispetto a quello standard a 3.5PN, ottimizza la stima dei parametri di marea dell'analisi dei dati BNS. Nel lavoro [2], incorporiamo in TEOBResumS i termini di self-spin dipendenti dall’equazione di stato (EOS) all'ordine next-to-next-to-leading (NNLO), insieme ad altri effetti (bilineari, cubici e quartici) al leading-order (LO). Qui, con la stessa cassetta degli attrezzi usata in[3], studiamo la dipendenza degli effetti di self spin legati all’EOS, e dimostriamo che le correzioni di ordine NLO e NNLO, a livello di interazione monopolo-quadrupolo, producono effetti di accelerazione di fase più marcati rispetto al corrispondente contributo LO; oltre a questo, si osserva altresì che una volta inclusi gli effetti di auto spin al NLO (3PN) nel Taylor F2, essi sono più attrattivi rispetto a quanto previsto dalla corrispondente descrizione EOB. Infine, abbiamo ottenuto un approssimante TaylorF2 che fornisce una rappresentazione analiticamente semplificata, ma fedele all'EOB, degli effetti di self-spin (effetti di coda inclusi) che può essere utile per migliorare gli attuali modelli di forma d'onda PN (o fenomenologici) per l’inspiralling di stelle di neutroni. Referenze: References: [1] Phys. Rev., D98(10):104052, 2018. [2] Phys. Rev., D99:044007, 2019. [3] Phys. Rev., D99:124051, 2019. [4] Phys. Rev., D97(8): 084016, 2018. [5] Phys. Rev., D100(10):104056, 2019. [6] Phys. Rev., D99(4):044051, 2019. [7] Phys. Rev. D 102, 024077 (2020) [8]Phys. Rev., D79:064004, 2009. [9] Phys. Rev., D94(10):104017, 2016. [10] Phys. Rev. X 9, 031040 [11] Phys. Rev., D95(12):124001, 2017.
The parameter estimation of gravitational wave events detected by LIGO and Virgo relies on analytical waveforms models, possibly calibrated (or informed) by Numerical Relativity simulations. The effective-one-body (EOB) model is one of the main analytical models available that can be efficiently used for analyzing both black hole and neutron star binaries. In this script we I) improve it in its various sectors, with the final aim to build a model that includes all the physical information available: in particular, the higher subdominant multipoles information, that is useful to optimize GW data analysis’ angular resolution [1, 4, 5, 7]; II) use it to develop high-order fast PN approximants for Bayesian analysis in LIGO and Virgo pipelines [3]; III) use it to study the self-spin effects of binary Neutron Stars on their own waveform [2]. One of the central building blocks of the EOB model is the factorized and resummed (circularized) multipolar post-Newtonian (PN) waveform introduced in Ref. [8] for nonspinning binaries. In Ref. [4], we extend up to ` = 6 (i.e. to high multipoles) the resummation approach of Nagar and Shah [9], since it has a better analytical/numerical relativity agreement than its precursor [8]. Ref. [4], updated to the case of a spinning particle of Schwartzschild problem in Ref. [5], has been used in order to update the spin-aligned, quadrupolar EOB model TEOBResumS, a C++ code [1] available in the LIGO Advanced Library (LAL) and cited in the GW catalogue [10], to a multipolar version [7]. Therefore, following the EOB-PN expansion technique defined in [11], Ref. [3] leads to a fast and accurate 5.5PN phenomenological approximant that, by including more point-mass information than the standard 3.5PN one, optimizes the tidal-parameter estimation of BNS data analysis. In Ref [2], we incorporate the EOS-dependent selfspin terms in TEOBResumS at next-to-next-to-leading (NNLO) order, together with other (bilinear, cubic and quartic) nonlinear-in-spin effects (at leading order, LO). Here, with the same toolbox used in Ref. [3], we study the EOS dependence of the self-spin effects and show that the next-to-leading order (NLO) and NNLO monopole-quadrupole corrections yield increasingly phase-accelerating effects compared to the corresponding LO contribution; that the standard TaylorF2 post-Newtonian (PN) treatment of NLO (3PN) EOS-dependent self-spin effects makes their action stronger than the corresponding EOB description; and, finally, we obtain a tail-augmented TaylorF2 approximant that yields an analytically simplified, EOB-faithful, representation of the EOS-dependent self-spin phasing that can be useful to improve current PN-based (or phenomenological) waveform models for inspiralling neutron star binaries. References: [1] Phys. Rev., D98(10):104052, 2018. [2] Phys. Rev., D99:044007, 2019. [3] Phys. Rev., D99:124051, 2019. [4] Phys. Rev., D97(8): 084016, 2018. [5] Phys. Rev., D100(10):104056, 2019. [6] Phys. Rev., D99(4):044051, 2019. [7] Phys. Rev. D 102, 024077 (2020) [8]Phys. Rev., D79:064004, 2009. [9] Phys. Rev., D94(10):104017, 2016. [10] Phys. Rev. X 9, 031040 [11] Phys. Rev., D95(12):124001, 2017.

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Forsgren, Mikael Fredrik. « Human Whole Body Pharmacokinetic Minimal Model for the Liver Specific Contrast Agent Gd-EOB-DTPA ». Thesis, Linköpings universitet, Medicinsk radiofysik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-76328.

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Magnetic resonance imaging (MRI) of the liver is an important non-invasive tool for diagnosing liver disease. A key application is dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). With the use of the hepatocyte specific contrast agent (CA) Gd-EOB-DTPA it is now possible to evaluate the liver function. Beyond traditional qualitative evaluation of the DCE-MRI images, parametric quantitative techniques are on the rise which yields more objective evaluations. Systems biology is a gradually expanding field using mathematical modeling to gain deeper mechanistic understanding in complex biological systems. The aim of this thesis to combine these two fields in order to derive a physiologically accurate minimal whole body model that can be used to quantitatively evaluate liver function using clinical DCE-MRI examinations. The work is based on two previously published sources of data using Gd-EOB-DTPA in healthy humans; i) a region of interest analysis of the liver using DCE-MRI ii) a pre-clinical evaluation of the contrast agent using blood sampling. The modeling framework consists of a system of ordinary differential equations for the contrast agent dynamics and non-linear models for conversion of contrast agent concentrations to relaxivity values in the DCE-MRI image volumes. Using a χ2-test I have shown that the model, with high probability, can fit the experimental data for doses up to twenty times the clinically used one, using the same parameters for all doses. The results also show that some of the parameters governing the hepatocyte flux of CA can be numerically identifiable. Future applications with the model might be as a basis for regional liver function assessment. This can lead to disease diagnosis and progression evaluation for physicians as well as support for surgeons planning liver resection.

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ASTON, DANIEL, et GUSTAV LINDSTRÖM. « Leasing av EVB : Modell för att hantera EU:s uppdaterade lagkrav vid EOL ». Thesis, KTH, Skolan för industriell teknik och management (ITM), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-299653.

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Efterfrågan på elfordon växer snabbt, med en ökning i Europa från 734 nyregistrerade elbilar 2010 till 550 000 år 2019 (Europeiska miljöbyrån, 2020). Medan denna trend fortsätter följer efterfrågan på litiumjonbatterier (LIB) en liknande väg. Europeiska unionen visar stort intresse för marknadsutvecklingen eftersom elektrifieringen av transporter är ett viktigt delmål på vägen mot noll-utsläpp av växthusgaser. EU utvecklar därför ett nytt direktiv för batterier där EV-batterier (EVB) har mer fokus än i det tidigare batteridirektivet från 2006. I det nya direktivet kommer EVB-tillverkaren att ha ett utökat ansvar, vilket innebär att den ansvarar för de EVB:er den för till marknaden i slutet av livslängden (EOL). Denna studie syftar till att undersöka den aktuella försörjningskedjan och designen av EVB:er, liksom de nuvarande och kommande tekniska lösningarna för återvinning av EVB:er. Detta för att sedan diskutera hur EVB-tillverkare ska agera gällande återvinning som svar på det nya EUdirektivet om batterier. Studien avgränsas till supply-chain och materialförsörjning; hur man utformar EVB:er för återvinning; och de nuvarande tekniska lösningarna för EVB:er som nått EOL. Grunden till studien är till fullo genomgång av vetenskapliga publikationer, tekniska rapporter och prognoser för marknads- och teknisk utveckling. Resultaten av den inlästa litteraturen visar en allmän enighet om att det kommer uppstå brist på litium och andra kritiska material för EVB-tillverkning vilket i slutändan kommer att leda till volatila priser. Det uppdaterade batteridirektivet är konstaterat att sätta tydliga mål för högre nivåer av återvunnet material i nya EVB:er, men det kommer också sätta tydliga mål att EVB:er som kan återanvändas i andra applikationer än EV:er måste återanvändas fram till EOL. Man har dragit slutsatsen att design för återvinning kommer att vara viktigt för att göra återvinningsprocessen lönsam. Vi har diskuterat möjligheterna och utmaningarna som leasing av EVB:er ger EVB-tillverkare i samband med leasing av EVB:er. Leasingen ger EVB-tillverkaren möjligheten att säkra EVB:er ochdärmed batterimaterial genom återvinning vid EOL. Positioneringen i värdekedjan har också diskuterats. Vi ser att det finns en uppenbar avvägning mellan att integrera uppströms och att förbli flexibel. Integrering uppströms möjliggör kontroll över EVB:er till EOL samt möjlighet att välja om man vill sälja det återvunna litiumet eller att använda det i sin egen produktion.
The demand of electric vehicles (EV) grows rapidly, with an increase in Europe from 734 newly registered EVs in 2010, to 550 000 in 2019 (European Environment Agency, 2020). While this trend continues, the demand of lithium ion batteries (LIB) follows a similar path. With electrified transportation being an important sub-goal on the road to net-zero greenhouse gas emissions, the European Union shows great interest for the development of the market. The EU is therefore developing a new directive for batteries in which EV batteries (EVB) have more focus than in theearlier Batteries Directive from 2006. In the new directive, producers of EVBs will have an extended responsibility, meaning that they are responsible for the batteries at end of life (EOL). This study aims at investigating the current supply-chain and design of EVBs, as well as the current and upcoming technical solutions for recycling of EVBs, in order to discuss how EVB manufacturers can and should act regarding recycling, as a response to the new EU directive on batteries. The study is delimited to supply-chain and material sourcing; how to design batteries for recycling; and the current technical solutions for EOL batteries. The research is solely based on literature review of scientific publications, technical reports and forecasts of market and technical development. The results of the literature shows a general consensus that there will be shortage of lithium andother critical materials for EVB manufacturing which ultimately will lead to unstable prices. The updated battery directive will most certainly set clear goals of higher levels of recycled material in new EVBs, but it will also implicate that batteries that can be used for other applications than EVs need to be reused until EOL. It has been concluded that designing for recycling will be importantfor making the recycling process economically viable. We have discussed the possibilities and challenges for EVB manufacturers associated with leasing EVBs as a business model where they can secure batteries and by extension material for recycling at EOL. The positioning in the value chain has also been discussed. We see that there is an apparent tradeoff between integrating upstream and remaining flexible. Integrating upstream will enable control over batteries at EOL as well as the opportunity to choose whether to sell the recycled lithium or to use it in their own production.

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Meinich, Morten. « An assessment of relevant costs in the Wilson EOQ model ». Thesis, Monterey, California. Naval Postgraduate School, 1988. http://hdl.handle.net/10945/22918.

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DeWinter, Edward A. « A Persistent Planning Model for EOD Training and Evaluation Unit Two ». Thesis, Monterey, California. Naval Postgraduate School, 2012. http://hdl.handle.net/10945/17353.

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The Explosive Ordnance Disposal Training and Evaluation Unit TWO (EODTEU TWO) trains Explosive Ordnance and Disposal (EOD) and Mobile Diving and Salvage (MDS) companies and platoons prior to worldwide deployments. This thesis describes EODSKED, an optimization model designed to assist EODTEU TWO in scheduling platoons that optimizes the use of limited resources and maximizes training value. EODSKED produces an optimized schedule that respects a large number of manpower and materiel resource constraints, such a schedule is difficult to achieve with the current manual scheduling process. Schedule modifications are often required after a schedule has been published; therefore, EODSKED incorporates persistence constraints to generate new schedules that match existing schedules closely.

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Whitley, Andrew. « Vibrational spectroscopic studies on the model lubricant 2-ethylhexyl benzoate (EHB) ». Thesis, Durham University, 1990. http://etheses.dur.ac.uk/6252/.

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In an attempt to investigate the relationship between microscopic and macroscopic fluid properties, like viscosity and density, a vibrational spectroscopic study of the model lubricant 2-ethylhexyl benzoate (EHB) was initiated. The variation in frequencies and band shapes of the vibrational modes of the molecule have been studied as a function of concentration, temperature and pressure. Estimates of correlation times for the reorientational motion of the phenyl ring of EHB, as a function of temperature, have been made from measurements of the Raman bands of the ring v(C-C) deformation mode and (^13)C N.M.R. spin lattice relaxation times. It has been shown using this data that the viscosity/temperature behaviour of EHB is dependent on the reorientational as opposed to the translational motion of the molecule. A noncoincidence of the Raman isotropic and anisotropic bands of the v(C=0) stretching mode of EHB has been seen and explained in terms of a resonance energy transfer (RET) process via transition dipole-transition dipole interactions, most probably as a consequence of preferential alignment via dipole-dipole interactions. It appears from dilution experiments that the EHB molecules do not become completely separated until below 2% mole-fraction. The infrared band of the v(C=0) stretching mode of EHB shows an unusual red shift with increased pressure to 6.5kbar, followed by a blue shift as the pressure is further increased. This has been explained as due to the competing effects of increased alignment of carbonyl dipoles (red shift) and the increase in the repulsive interactions (blue shift). All the other bands exhibit blue shifts, of varying degree, with increased pressure, showing that the repulsive forces dominate the shifts. The spectral changes are consistent with chain extension and increased interchain interactions with increased pressure. The band widths of all the vibrational modes increase with pressure consistent with an increase in vibrational relaxation rate. The fluid appears to exhibit a phase change close to 6.5kbar.

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Parthasarathy, Meghana. « Analyzing Warehouse-Retailer Interaction using a Modified Economic Order Quantity (EOQ) Model ». Ohio University / OhioLINK, 2004. http://www.ohiolink.edu/etd/view.cgi?ohiou1103228627.

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Skår, Helene. « Simulation of Surfactant EOR in a Mechanistic Model with Fracture and Ekofisk Properties ». Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for petroleumsteknologi og anvendt geofysikk, 2014. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-25910.

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Large amounts of oil are left in reservoirs after primary and secondary recovery. To recovery as much of the remaining oil as possible, EOR techniques as chemical flooding is considered. Naturally fractured carbonates have often large amount of residual oil left in the reservoir after primary and secondary production periods. Carbonates are in general more complex reservoirs than sandstones, thus must recovery methods be tailored for the environment of the reservoir system. Chemical EOR has become more attractive after the financial crisis in 2008 because of the high oil prices. Ekofisk is naturally fractured chalk reservoir, and is the largest, oldest and longest producing reservoir on Norwegian continental shelf. To improve the recovery is surfactant injection considered as a possible EOR method. A mechanist reservoir model with Ekofisk reservoir properties and a single fracture was made with the purpose to investigate the potential of surfactant injection in Ekofisk. Several parameters that effect the performance of surfactants was investigated and the recovery results were compared with a waterflood basecase. In addition was a mechanistic model with four fractures made for further investigation of surfactant flow in a fracture network and for comparison of the performance of a surfactant flood with surfactant-polymer flood. The author’s simulation results show that surfactant injection should be considered for the field, but more research with a more advanced reservoir model with respect to possible wettability alteration, a larger fracture network and heterogeneity should be done. The model shows poor sweep efficiency in layers far from the fracture in the model, thus should an eventual chemical flood in Ekofisk be considered done with polymers. Surfactant concentration in the injection solution affects the surfactant performance the most. For the single fracture model is the recovery increased with 2,8% when surfactants are injected, and NPV was increased with 8,31E+06 $. For the 9-block model with four fractures, was the recovery improved with 3% for the surfactant-polymer flood compared with a surfactant flood. Also the NPV was increased with 3,71E+06$.

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Scorgie, Donald. « A fast forward model for the assimilation of radiances from the EOS-MLS ». Thesis, University of Edinburgh, 2006. http://hdl.handle.net/1842/14367.

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In this thesis the idea of using neural networks as a forward model for the EOS-MLS (Earth Observation System – Microwave Limb Sounder) is considered for a direct assimilation scheme. Neural networks are a type of non-linear regression technique that can provide fast, accurate results and are used extensively in many different fields. Here a neural network is constructed to act as a forward model for the EOS-MLS. The neural network uses a temperature profile and tangent pressure levels as inputs and produces the corresponding radiance profile for one channel of the EOS-MLS. The work here primarily concentrates on one band of the EOS-MLS that is centred on an oxygen line and whose radiances are affected only by temperature for the majority of the channels. It shows that a neural network can function as a forward model in this case, producing radiances that are within instrument noise and for most channels, within half the instrument noise. Adding ozone to the forward model affects the radiances in only two channels of this band, increasing the radiances in some minor frames by around ~10K. It was found that this difference could be accounted for in the neural network forward model by adding ozone to the inputs. A second band, which is centred on an ozone line, is briefly considered. It was found that above 150hPa the radiances from this band could be modelled well using a neural network. Below this height, the neural network produced large errors in radiance (of around 1.5K – four times the instrument noise). This is thought to be due to the effects of water vapour. A problem specific to limb sounders that must be faced when doing direct assimilation is determining the tangent pressures of the radiances. During retrieval, these tangent pressures are normally retrieved as part of the state vector and discarded. For an assimilation process, these tangent pressures may be unavailable and have to be deduced in some way. Here, a neural network is used to retrieve tangent pressures outside the assimilation process. These retrieved tangent pressures can then be used by the forward model and assumed to be correct. It was found that tangent pressures could be retrieved with an accuracy of around 50m, much better than required for a forward model. The final problem faced within this thesis is the creation of the Jacobian of the instrument forward model. This is the derivative of the radiances with respect to the state vector and is used by the assimilation process to update the model fields during the assimilation process.

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Livres sur le sujet "EOB Model"

Meinich, Morten. An assessment of relevant costs in the Wilson EOQ model. Monterey, Calif : Naval Postgraduate School, 1988.

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Scotti, Chiara. A bivariate model of Fed and ECB main policy rates. Washington, D.C : Federal Reserve Board, 2006.

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Astrup, Poul. Udvikling af EDB-model for stationaer turbulent 3-D gas-partikel stromming. Roskilde, Denmar : Forskningscenter Riso, 1988.

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1949-, Davis D. A., Tan M. K et Langley Research Center, dir. Development of the CSI phase-3 evolutionary model testbed. Hampton, Va : National Aeronautics and Space Administration, Langley Research Center, 1994.

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Thomas, Nehrkorn, Grassotti Christopher et United States. National Aeronautics and Space Administration., dir. Distortion representation of forecast errors for model skill assessment and objective analysis : Technical report. [Washington, DC : National Aeronautics and Space Administration, 1996.

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United States. National Aeronautics and Space Administration., dir. Earth Observing System (EOS)/Advanced Microwave Sounding Unit-A (AMSU-A) Structural Math Model - A1. Azusa, Calif : Aerojet, 1996.

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Salstein, David A. Diagnostic studies with GLA fields. [Cambridge, MA] : Atmospheric and Environmental Research, Inc., 1997.

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Ross, Kevin. Market predictability of ECB monetary policy decisions : A comparative examination. [Washington, D.C.] : International Monetary Fund, European I Department, 2002.

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Richards, Nathan. Virtual modeling and 3D photogrammetry for maritime heritage : Exercises in EOS PhotoModeler Pro 5.0. Greenville, N.C : Program in Maritime Studies, East Carolina University, 2006.

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Reuter, WG, JH Underwood et JC Newman, dir. Surface-Crack Growth : Models, Experiments, and Structures. 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959 : ASTM International, 1990. http://dx.doi.org/10.1520/stp1060-eb.

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Chapitres de livres sur le sujet "EOB Model"

Muckstadt, John A., et Amar Sapra. « EOQ Model ». Dans Principles of Inventory Management, 17–45. New York, NY : Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-68948-7_2.

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Kolovos, Dimitrios S., Richard F. Paige et Fiona A. C. Polack. « The Epsilon Object Language (EOL) ». Dans Model Driven Architecture – Foundations and Applications, 128–42. Berlin, Heidelberg : Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11787044_11.

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Mendoza, Abraham, et José A. Ventura. « EOQ Models with Two Modes of Freight Transportation and All-Units Quantity Discounts ». Dans Handbook of EOQ Inventory Problems, 139–53. Boston, MA : Springer US, 2013. http://dx.doi.org/10.1007/978-1-4614-7639-9_7.

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Hellwig, Marcus. « Vorstellung der Equibalancedistribution, Eqb ». Dans SIR - Modell durch eine neue Dichte unterstützt, 53–60. Wiesbaden : Springer Fachmedien Wiesbaden, 2022. http://dx.doi.org/10.1007/978-3-658-36476-2_9.

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Mansuy, Daniel, Pierrette Battioni et Jean-Paul Battioni. « Chemical model systems for drug-metabolizing cytochrome-P-450-dependent monooxygenases ». Dans EJB Reviews 1989, 99–117. Berlin, Heidelberg : Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-75189-9_7.

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Schwarz, Leroy B. « The Economic Order-Quantity (EOQ) Model ». Dans Building Intuition, 135–54. Boston, MA : Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-73699-0_8.

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Atan, Zümbül, et Lawrence V. Snyder. « EOQ Models with Supply Disruptions ». Dans Handbook of EOQ Inventory Problems, 43–55. Boston, MA : Springer US, 2013. http://dx.doi.org/10.1007/978-1-4614-7639-9_3.

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Chen, Jing, et Genevieve Mushaluk. « Coordinating a Supply Chain with an EOQ Model ». Dans Handbook of EOQ Inventory Problems, 201–20. Boston, MA : Springer US, 2013. http://dx.doi.org/10.1007/978-1-4614-7639-9_10.

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Hellwig, Marcus. « Zufallsstreubereiche der NV und der Eqb ». Dans SIR - Modell durch eine neue Dichte unterstützt, 49–52. Wiesbaden : Springer Fachmedien Wiesbaden, 2022. http://dx.doi.org/10.1007/978-3-658-36476-2_8.

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Silaghi, Raul, et Alfred Strohmeier. « Critical Evaluation of the EJB Transaction Model ». Dans Scientific Engineering for Distributed Java Applications, 15–28. Berlin, Heidelberg : Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-36520-6_2.

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Actes de conférences sur le sujet "EOB Model"

de Fries, S., U. Hofmann et A. Das. « BOF Processing by a Static and Dynamic Model With Automatic EOB Detection : Recent Results ». Dans AISTech2019. AIST, 2019. http://dx.doi.org/10.33313/377/101.

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Tang, Mimi, Shi-Ting Feng, Sui Peng et Ming Kuang. « IDDF2018-ABS-0098 Preoperative prediction of microvascular invasion in hepatocellular cancer : a radiomics model using GD-EOB-DTPA enhanced MRI ». Dans International Digestive Disease Forum (IDDF) 2018, Hong Kong, 9–10 June 2018. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2018. http://dx.doi.org/10.1136/gutjnl-2018-iddfabstracts.206.

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Chen, Yuyan. « IDDF2020-ABS-0092 Prediction of post-hepatectomy liver failure in patients with hepatocellular carcinoma based on Gd-EOB-DTPA-Enhanced MRI : A LF scoring model ». Dans Abstracts of the International Digestive Disease Forum (IDDF), 22–23 November 2020, Hong Kong. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2020. http://dx.doi.org/10.1136/gutjnl-2020-iddf.152.

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Park, R. W. « Crack Detection, Localization and Estimation of the Intensity in a Turbo Rotor ». Dans ASME 1996 Turbo Asia Conference. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/96-ta-031.

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The goal of this paper is to describe an advanced method of a crack detection, a new way to localize the crack position and to estimate the intensity of the depth with reference to a rotating shaft. As a first step, the shaft is physically modelled with a finite element method as usual and the dynamic mathematical model is derived from it using the Hamilton-principle and in this way the system is modelled by various subsystems. The equations of motion with crack is established by adaption of the local stiffness change through breathing and gaping from the crack to the equation of motion with undamaged shaft. This is supposed to be regarded as reference for the given system. Based on the fictitious model of the time behaviour induced from vibration phenomena measured at the bearings, a nonlinear State Observer is designed in order to detect the crack on the shaft. This is elementary NL-observer (EOB). Using the elementary observer, an Estimator (Observer) Bank is established and arranged at the certain position on the shaft. In case a crack is found and its position is known, the procedure for the estimation of the depth is going to begin.

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Annighoefer, Bjoern, Matthias Brunner, Bastian Luettig et Julian Schoepf. « EOQ : An Open Source Interface for a More DAMMMMN Domain-specific Model Utilization ». Dans 2021 ACM/IEEE International Conference on Model Driven Engineering Languages and Systems Companion (MODELS-C). IEEE, 2021. http://dx.doi.org/10.1109/models-c53483.2021.00075.

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Shaikh, Jawad Azeem, et Pashupati Sah. « Experimental PVT data needed to develop EoS Model for EOR Projects ». Dans SPE Enhanced Oil Recovery Conference. Society of Petroleum Engineers, 2011. http://dx.doi.org/10.2118/144023-ms.

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De Carlos, Xabier, Goiuria Sagardui et Salvador Trujillo. « Supporting CRUD Model Operations from EOL to SQL ». Dans 4th International Conference on Model-Driven Engineering and Software Development. SCITEPRESS - Science and and Technology Publications, 2016. http://dx.doi.org/10.5220/0005644401530160.

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Alanaisi, Isa, Lakshi Konwar, Ali AlMeftah et Ebrahim Alawainati. « CO2 and Ethane-Based Enhanced Oil Recovery (EOR) : Laboratory Evaluations and Simulation Studies for a Matured Carbonate Reservoir in Bahrain ». Dans ADIPEC. SPE, 2022. http://dx.doi.org/10.2118/211429-ms.

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Abstract The Mauddud reservoir discovered in 1932 in Bahrain is now in a mature stage of development. Crestal gas injection (GI) in the oil bearing, under saturated, layered, and heavily faulted carbonate reservoir has continued to be the dominant drive mechanism since 1938. Current strategy for maximizing reservoir potential and reduce production decline with infill drilling, workovers, and routine maintenance of wells are not adequate for a matured reservoir like Mauddud. As such, a detailed feasibility study is being carried out to identify the most appropriate enhanced oil recovery (EOR) process for this reservoir and define a strategy for further evaluation and implementation of the most promising EOR options. This paper aims to present detailed design and results of laboratory experiments using CO2 and ethane gas en route to sector modeling studies in three (3) selected large areas. A high-level cost estimate is also performed using the results from the pattern simulations. The gas EOR laboratory study consisted of performing swelling and slim tube tests using the recombined Mauddud live oil and two injection gases: carbon dioxide (CO2) and ethane (C2). The swelling tests and the corresponding constant composition experiments (CCE) were matched using a 16-component equation of state (EOS) model. Slim tube simulations performed with the tuned EOS were able to replicate the oil recovery values from the slim tube tests. Representative sector and pattern simulation models were developed to estimate the EOR production potential from the Mauddud reservoir. The sector model developed was calibrated to the historical production, injection, and pressure data. An extensive sensitivity study was conducted to match the fluid flow dynamics of the reservoir. The history matched sector model was used to select and develop pattern simulation models that were used to estimated EOR production potential. Swelling tests conducted with CO2 and Ethane shows the effect of oil swelling and changes in oil properties such as density, viscosity, formation volume factor, and solution GOR. The elevation in swelling factors and the reduction in oil viscosity exhibit the benefits of using CO2 and ethane as injection sources for Mauddud. Solid precipitation on the PVT cell window was observed, indicating the possibility of asphaltene precipitation with CO2 and C2 injection. CO2 slim tube tests showed a minimum miscibility pressure (MMP) of about 1,762 psig, which is around 800 psi higher than the current reservoir pressure. Therefore, CO2 injection under miscible conditions is not viable in Mauddud reservoir. Ethane gas mixture and Mauddud reservoir live oil showed an MMP of 1,022 psig. Ethane pattern simulations showed incremental oil recovery factors over the no-further-activities (NFA) between 17.7 and 27.6 percent of the original oil-in-place (OOIP). The laboratory and sector simulation results are crucial to explore the feasibility of any EOR project and will serve as inputs to detailed economic evaluation as well as pilot design and facilities planning.

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Negahban, Shahin, Karen Schou Pedersen, Pashupati Sah, Mahmoud Ali Basioni et Jawad Azeem. « An EoS Model for a Middle East Reservoir Fluid with an Extensive EOR PVT Data Material ». Dans Abu Dhabi International Petroleum Exhibition and Conference. Society of Petroleum Engineers, 2010. http://dx.doi.org/10.2118/136530-ms.

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Vandiver, Ben, Shreya Prasad, Pratibha Rana, Eden Zik, Amin Saeidi, Pratyush Parimal, Styliani Pantela et Jaimin Dave. « Eon Mode ». Dans SIGMOD/PODS '18 : International Conference on Management of Data. New York, NY, USA : ACM, 2018. http://dx.doi.org/10.1145/3183713.3196938.

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Rapports d'organisations sur le sujet "EOB Model"

Crockett, Scott. Extension Model : Diamond Phenolic EOS. Office of Scientific and Technical Information (OSTI), août 2013. http://dx.doi.org/10.2172/1089872.

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Andrews, Stephen Arthur, et Andrew Mcleod Fraser. Quantifying Uncertainty in an EOS Model. Office of Scientific and Technical Information (OSTI), décembre 2017. http://dx.doi.org/10.2172/1412915.

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Pichersky, Eran, Alexander Vainstein et Natalia Dudareva. Scent biosynthesis in petunia flowers under normal and adverse environmental conditions. United States Department of Agriculture, janvier 2014. http://dx.doi.org/10.32747/2014.7699859.bard.

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The ability of flowering plants to prosper throughout evolution, and for many crop plants to set fruit, is strongly dependent on their ability to attract pollinators. To that end many plants synthesize a spectrum of volatile compounds in their flowers. Scent is a highly dynamic trait that is strongly influenced by the environment. However, with high temperature conditions becoming more common, the molecular interplay between this type of stress and scent biosynthesis need to be investigated. Using petunia as a model system, our project had three objectives: (1) Determine the expression patterns of genes encoding biosynthetic scent genes (BSGs) and of several genes previously identified as encoding transcription factors involved in scent regulation under normal and elevated temperature conditions. (2) Examine the function of petunia transcription factors and a heterologous transcription factor, PAPl, in regulating genes of the phenylpropanoid/benzenoid scent pathway. (3) Study the mechanism of transcriptional regulation by several petunia transcription factors and PAPl of scent genes under normal and elevated temperature conditions by examining the interactions between these transcription factors and the promoters of target genes. Our work accomplished the first two goals but was unable to complete the third goal because of lack of time and resources. Our general finding was that when plants grew at higher temperatures (28C day/22C night, vs. 22C/16C), their scent emission decreased in general, with the exception of a few volatiles such as vanillin. To understand why, we looked at gene transcription levels, and saw that generally there was a good correlation between levels of transcriptions of gene specifying enzymes for specific scent compounds and levels of emission of the corresponding scent compounds. Enzyme activity levels, however, showed little difference between plants growing at different temperature regimes. Plants expressing the heterologous gene PAPl showed general increase in scent emission in control temperature conditions but emission decreased at the higher temperature conditions, as seen for control plants. Finally, expression of several transcription factor genes decreased at high temperature, but expression of new transcription factor, EOB-V, increased, implicating it in the decrease of transcription of BSGs. The major conclusion of this work is that high temperature conditions negatively affect scent emission from plants, but that some genetic engineering approaches could ameliorate this problem.

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Sjue, Sky K., et Michael B. Prime. Analytic EoS and PTW strength model recommendation for Starck Ta. Office of Scientific and Technical Information (OSTI), septembre 2016. http://dx.doi.org/10.2172/1304821.

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Henneges, G., et S. Kleinheins. AFDM : An advanced fluid-dynamics model. Volume 6 : EOS-AFDM interface. Office of Scientific and Technical Information (OSTI), janvier 1994. http://dx.doi.org/10.2172/10140789.

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Sjue, Sky K., et Michael Bruce Prime. Starck Ta PTW strength model recommendation for use with SESAME 93524 EoS. Office of Scientific and Technical Information (OSTI), février 2017. http://dx.doi.org/10.2172/1345178.

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Morgan, David, Donald Remson, Matthew Wallace et Vello Kuuskraa. User's Manual for the FE/NETL Onshore CO2 EOR Cost Model, Version 1. Office of Scientific and Technical Information (OSTI), juillet 2020. http://dx.doi.org/10.2172/1661585.

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Plohr, JeeYeon. The Preston-Tonks-Wallace (PTW) Model Parameterization of Al-6061 With Sesame EoS. Office of Scientific and Technical Information (OSTI), mai 2022. http://dx.doi.org/10.2172/1869585.

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Al-Qaisi, Mohmmad, Erin Horst, Sara Kvidera, Johana Mayorga, Carrie Shouse, Samantha Lei, Leo L. Timms et Lance H. Baumgard. Developing a Heat Stress Model in Dairy Cows Using an Electric Heat Blanket(EHB). Ames (Iowa) : Iowa State University, janvier 2017. http://dx.doi.org/10.31274/ans_air-180814-368.

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Grove, John W. Eulerian Applications Project - xRage The xRage Equation of State : Supported EOS Models. Office of Scientific and Technical Information (OSTI), septembre 2019. http://dx.doi.org/10.2172/1569606.

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