Articles de revues : « Emblica officinalis »

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Mirajkar, Dr Chaitali, et Dr Umesh Hambire. « Oral Health Benefits of Phyllanthus Emblica ». Middle East Research Journal of Dentistry 1, n^o 1 (27 décembre 2021) : 23–26. http://dx.doi.org/10.36348/merjd.2021.v01i01.004.

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Abstract: Phyllanthus emblica also known as Emblica officinalis belongs to the Euphorbiaceae family. It is also known as Indian gooseberry, emblic myrobalans, and Amla (in Hindi). It has anti-inflammatory, antioxidant, cryoprotective, antiaging, antidiabetic and hepatoprotective properties. The fruit of Amla is rich in vitamin C (ascorbic acid) and contains several bioactive phytochemicals. It also contains polyphenols such as ellagic acid, chebulinic acid, gallic acid, chebulagic acid, apeigenin, quercetin, corilagin, leutolin. It has antimicrobial and anti-ulcerative property. It is used for management of oral ulcers and periodontal diseases.

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Yadav Abhishek et Samanta Krishanu. « Formulation and evaluation of herbal ointment using Emblica officinalis extract ». World Journal of Advanced Research and Reviews 9, n^o 2 (28 février 2021) : 032–37. http://dx.doi.org/10.30574/wjarr.2021.9.2.0040.

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Herbal medicine prepare various part of plant are used like flower, leaves, seeds, root etc. Instead off an herbal drug is design as the alternative formulation for the external use in the form of ointment. For the medicinal use the herbal ointment apply externally on human body. The main aims of this research are preparation of herbal ointment from the Emblica officinalis plants the antibacterial activity. Under this research work, it is design as herbal ointment with the help of methanolic extract of Emblica officinalis and determines the anti-bacterial capacity on it. In vitro study the antibacterial activity of the methanolic extracts of dried leaves of Emblica officinalis are determine by using the Agar cup plate method versus different bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa etc. By blending the methanolic extract of Emblica officinalis (10 % w/w) into aqueous cream we formulated herbal ointment. The emulsifying agent and simple ointment bases are added in above herbal ointment for increase the antibacterial effectiveness during in vitro evaluation. The herbal ointment is also better in comparison to a commercial brand of Gentamicin ointment. Emblica officinalis (Family Euphorbiaceae) are broadly used in traditional system of medicine throughout different part of India. It is used in the treatment of cold, anemia, dysentery, fever, gravel, sores. It is very important to standardize the plant part pharmacognostically for its utilization in different formulation. The current study deals with the determination of formulation and evaluation of herbal ointment using Emblica officinalis extract.

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Zulfiqar, Hadia, Sitwat Amna, Muhammad Suhail, Tayyaba Muzaffar, Javaid Iqbal et Saba Amjad. « ROLE OF EMBLICA OFFICINALIS IN COPPER INDUCED LIVER TOXICITY IN ADULT ALBINO RATS ». Pakistan Postgraduate Medical Journal 34, n^o 04 (30 décembre 2023) : 173–76. http://dx.doi.org/10.51642/ppmj.v34i04.489.

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Background: Copper (Cu) is an important heavy metal used widely in all industries. However, its toxicity on various organs is established. Emblica officinalis, commonly known as Amla, is a potential antioxidant and can prevent Cu induced hepatotoxicity. Objective: To evaluate the effects of Emblica officinalis extract on liver histology and Alanine Aminotransferase (ALT) levels after Cu induced toxicity on adult albino rats. Methods: This was an experimental study of 28 days duration. 36 adult male albino rats were divided into three groups of twelve animals each. Group A was control group in which rats were given 1.5 ml normal saline while group B rats were given CuSO4 200mg/kg b.w./day. Rats in Group C were given both CuSO4 (200mg/kg b.w/day) and Emblica officinalis fruit extract (300mg/kg bw/day). The agents were fed via orogastric tube for four weeks and rats were sacrificed 24 hours after administration of last dose. Results: Cu treated rats showed necrosis of hepatocytes and Increased serum ALT levels. Emblica officinalis co-treatment attenuated Cu-induced hepatic necrosis and variation in ALT levels. The difference among the groups was statistically significant with p-value <0.05. Conclusion: Emblica officinalis fruit extract improves liver function in Cu induced hepatotoxicity by limiting oxidative damage.

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Patel, Anandkumar M. « A Critical Review of Pandughni Vati ». Healer 3, n^o 2 (19 mars 2023) : 5. http://dx.doi.org/10.51649/healer.135.

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Pandughni Vati(Anubhuta)contains eight Ayurvedic drugs i.e. Amalaki (Emblica officinalis), Bibhitaki (Terminalia bellerica), Shunthi (Zingiber officinale Roscoe.), Maricha (Piper nigrum Linn.) Pippali (Piper longum Linn), Katuki (Picrorhiza kurroa), Punarnava (Boerhavia diffusa Linn.) and Vidanga (Embelia ribes Burm.f.) as well as Bhavana Dravya like Kumari(Aloe vera Miller.), Punarnava (Boerhavia diffusa Linn.), Amalaki (Emblica officinalis) and Gaumutra (Cow’s Urine) as this Formulation Developed by AYUSH Department, Ministry of Health and Family welfare, Govt. of India (Anubhuta). Pandughni Vati(Anubhuta) has properties of Katu-Tikta Rasa, Laghu, Ruksha Guna, Ushna Virya and Katu Vipaka (pungent). The drug has several properties as anti-viral, anti-bacterial, imunomodulatory, hepato protective due to its various components. These properties make it an effective drug for various general and liver diseases.

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S, Tapade S., Punam P. Suryawanshi, Priti Mane, Priyanka Dappadwad, Rameshwar Sangle, Ramraje Lahade, Rutuja Tandle et Rutuja Bedre. « Pharmacological and Medicinal Important of Plant Phyllanthus Emblica Linn. (Syn.Emblica Officinalis), Indian Gooseberry ». International Journal for Research in Applied Science and Engineering Technology 11, n^o 10 (31 octobre 2023) : 1473–80. http://dx.doi.org/10.22214/ijraset.2023.56206.

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Abstract: The plant names phyllanthus emblica linn (Amla) are very precious gift of nature which have a vital role in health care. Nowadays, use of herbal product become most important for humans over the world. This drug is very useful for the treatment of disease. The most important part of this plant (phyllanthus emblica) is fruit. Phyllanthus emblica Linn. (syn. Emblica officinalis), commonly known as Indian gooseberry or amla, belongs to the family Euphorbiaceae. Though all parts of the plant are used for medicinal purposes, the fruits especially are found tremendous pharmacological applications. They are highly nutritious and form an important dietary source of vitamin C, amino acids, and minerals. Emblica Officinalis Plant is reported to have diverse Pharmacological actions like Adaptogenic Activity, Hepatoprotective Activity, Anti-Bacterial Activity, Anti-Hyperlipidemia Activity, Hypolipidemic Activity, Anti-Atherogenic Activity, Immunostimulatory Activity, Anti-oxidant Activity, Anti-Tumor Activity,Anti-Microbial Activity,Chondroprotective Activity, Analgesic Activity, Anti-Inflammatory Activity & AntiDiarreheal Activity. Emblica Officinalis plant is used in the treatments of various ailments. The diverse ailments like cancer, Atherosclerosis, Inflammation, Osteoporosis, Nuerological disorders, Hypertention and other infectious disorders.

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Deori, Chinmoyee, Swarnamoni Das et Sushanta Kumar Bordoloi. « Role of Emblica officinalis (amla) in the prophylaxis of hepatic injury by carbon tetrachloride (CCl4) in albino rats ». International Journal of Basic & ; Clinical Pharmacology 6, n^o 8 (22 juillet 2017) : 1992. http://dx.doi.org/10.18203/2319-2003.ijbcp20173284.

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Background: The objective of the study was to evaluate the hepatoprotective activity of fruits extract of Emblica officinalis on carbon tetrachloride induced hepatotoxicity in Albino rats. Liver is vulnerable to wide variety of metabolic, toxic, microbial, circulatory and neoplastic insults. The dominant primary diseases of the liver are viral hepatitis, alcoholic liver disease and hepatocellular carcinoma. Due to absence of reliable drugs management of liver ailments in the modern medicine, plants and natural products are providing to be good hepatoprotectants as evident from voluminous published work on their hepatoprotective potentials.Methods: The required amount of fresh fruits of Emblica officinalis was collected and dried at room temperature. The dried fruit ground into powdered and was prepared by percolation method using 95% ethanol. Acute oral toxicity test of the fruits extract was performed as per OECD 423 guidelines. Carbon tetrachloride was used as the hepatotoxin. Silymarin suspension 100mg was used as a standard drug in this study.Results: The study was carried out with an attempt to evaluate the hepatoprotective activity of Emblica officinalis in carbon tetrachloride induced hepatic injury in albino rats. The results were analysed by using one way ANOVA followed by Dunnett’s test and (p <0.05) was considered significant.Conclusions: The present study shows that the Emblica officinalis has significant hepatoprotective activity in rats with carbon tetrachloride induced liver injury. Emblica officinalis is a commonly used traditional herb, which is safe, cost effective and grows widely in India and used by different ethnic groups for various diseases. That is why Emblica officinalis, a commonly used natural herb, deserve further consideration in order to establish its potential as safe economical hepatoprotective agent.

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Mansoury, Manal. « A Review of the Antidiabetic, Antihyperlipidemic, and Related Metabolic Disorder Documented Activities of Emblic Fruits (Phyllanthus emblica L.) ». Journal of Complementary Medicine Research 14, n^o 1 (2022) : 1. http://dx.doi.org/10.5455/jcmr.2022.13.05.01.

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Diabetes is a risky metabolic chronic sickness that threatens the lives and health of individuals, families, and communities everywhere. Management of diabetes and related metabolic syndrome (MS) relies heavily on diet. There are reports of folk plants showing varying levels of antihyperglycemic activity. Phyllanthus emblica Linn (syn. Emblica officinalis) (often referred to Emblic, Indian gooseberry, or amla) is a perennial tree in the Euphorbiaceae family. Due to the high concentration of phenolic compounds, Emblic fruit may be considered a plant source of natural antioxidants. Numerous studies have demonstrated Emblic fruit’s benefits on humans and animals that are antihyperglycemic, anti-inflammatory, antihyperlipidemic, antibacterial, analgesic and antipyretic, adaptogenic, hepatoprotective, anticancer, antiulcerogenic, and antioxidant. This review provided an overview of the published scientific studies (experimental and clinical) that documented the potential antidiabetic and antihyperlipidemic benefits associated with consuming Emblic fruits. In addition, the possible activity regarding related metabolic syndrome and diabetes complications was assessed.

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Veeraraghavan, Vishnu Priya. « Antioxidant effects of Emblica officinalis and Zingiber officinalis on arsenic and lead induced toxicity on Albino rats ». Bioinformation 17, n^o 2 (28 février 2021) : 295–305. http://dx.doi.org/10.6026/97320630017295.

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It is of interest to document the effect of Emblica officinalis (E. officinalis) and Zingiber officinalae (Z. officinalae) leaf extract on reactive oxygen species, antioxidant potential changes in arsenic and lead-induced toxicity in male rats. We used 8 groups of adult male Wistar rats with 1 control group for this study. The animals were divided into Group I: Control and Group II: Lead and sodium arsenite induced rats (animals were induced for metal toxicity by the combined administration of arsenic (13.8 mg/kg body weight) and lead (116.4 mg/kg body weight). These doses were administered by gastric intubation during 14 consecutive days using known standard procedures. Arsenic and lead induced rats treated with ethanolic extract of Emblica officinalis (60 mg/kg body weight/day, orally for 45 days) are group III rats.Group IV animals are arsenic and lead induced rats treated orally with ethanolic extracts of E. officinalis (120 mg/kg body weight/day for 45 days). Group V animals are arsenic and lead induced rats treated orally with ethanolic extracts of Z. officinalae (60 mg/kg body weight/day for 45 days). Group VI animals are arsenic and lead induced rats orally treated with ethanolic extracts of Zingiber officinalis (120 mg/kg body weight/day for 45 days). Group VII animals are arsenic and lead induced rats treated orally with ethanolic extracts of E. officinalis and Z. officinalae (60 + 60 mg/kg body weight/day for 45 days). Group VIII animals are arsenic and lead induced rats treated orally with ethanolic extracts of E. officinalis and Z. officinalae (120 + 120 mg/kg body weight/day, orally for 45 days). Normal Control animals were treated orally with ethanolic extracts of E. officinalis (120mg/kg body weight) + Z. officinalae (120mg/kg body weight) for 45 days. The control and experimental animals were then subjected to analysis for oxidative stress markers such as H2O2, *OH, and lipid peroxidation (LPO), antioxidant enzymes in addition to liver and kidney function markers. Results: Arsenic and lead induced rats showed a significant increase in the levels of reactive oxygen species (H2O2, OH* and LPO) with concomitant alterations in the renal and liver tissues. However, enzymic and non-enzymic antioxidant levels were decreased. Nevertheless, an oral effective dose of E. officinalis and Z. officinalae (120 + 120 mg/kg body weight/day increased the antioxidant enzymes and retrieved the altered levels of ROS and LPO that were induced by arsenic and lead. Thus, we show that E. officinalis and Z. officinalae leaf extract exhibits nephroprotective and hepatoprotective role through the restoration of reactive oxygen species and antioxidant enzymes in the kidney and liver tissue of Arsenic and Lead-induced nephrotoxicity and hepatotoxicity in rats. Hence, E. officinalis and Z. officinalae leaf extract are potential therapeutic options for the treatment of metal toxicity-induced kidney and liver diseases.

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Vishnu Priya, Veeraraghavan. « Antioxidant effects of Emblica officinalis and Zingiber officinalis on arsenic and lead induced toxicity on Albino rats ». Bioinformation 17, n^o 2 (28 février 2021) : 295. http://dx.doi.org/10.6026//97320630017295.

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It is of interest to document the effect of Emblica officinalis (E. officinalis) and Zingiber officinalae (Z. officinalae) leaf extract on reactive oxygen species, antioxidant potential changes in arsenic and lead-induced toxicity in male rats. We used 8 groups of adult male Wistar rats with 1 control group for this study. The animals were divided into Group I: Control and Group II: Lead and sodium arsenite induced rats (animals were induced for metal toxicity by the combined administration of arsenic (13.8 mg/kg body weight) and lead (116.4 mg/kg body weight). These doses were administered by gastric intubation during 14 consecutive days using known standard procedures. Arsenic and lead induced rats treated with ethanolic extract of Emblica officinalis (60 mg/kg body weight/day, orally for 45 days) are group III rats.Group IV animals are arsenic and lead induced rats treated orally with ethanolic extracts of E. officinalis (120 mg/kg body weight/day for 45 days). Group V animals are arsenic and lead induced rats treated orally with ethanolic extracts of Z. officinalae (60 mg/kg body weight/day for 45 days). Group VI animals are arsenic and lead induced rats orally treated with ethanolic extracts of Zingiber officinalis (120 mg/kg body weight/day for 45 days). Group VII animals are arsenic and lead induced rats treated orally with ethanolic extracts of E. officinalis and Z. officinalae (60 + 60 mg/kg body weight/day for 45 days). Group VIII animals are arsenic and lead induced rats treated orally with ethanolic extracts of E. officinalis and Z. officinalae (120 + 120 mg/kg body weight/day, orally for 45 days). Normal Control animals were treated orally with ethanolic extracts of E. officinalis (120mg/kg body weight) + Z. officinalae (120mg/kg body weight) for 45 days. The control and experimental animals were then subjected to analysis for oxidative stress markers such as H2O2, *OH, and lipid peroxidation (LPO), antioxidant enzymes in addition to liver and kidney function markers. Results: Arsenic and lead induced rats showed a significant increase in the levels of reactive oxygen species (H2O2, OH* and LPO) with concomitant alterations in the renal and liver tissues. However, enzymic and non-enzymic antioxidant levels were decreased. Nevertheless, an oral effective dose of E. officinalis and Z. officinalae (120 + 120 mg/kg body weight/day increased the antioxidant enzymes and retrieved the altered levels of ROS and LPO that were induced by arsenic and lead. Thus, we show that E. officinalis and Z. officinalae leaf extract exhibits nephroprotective and hepatoprotective role through the restoration of reactive oxygen species and antioxidant enzymes in the kidney and liver tissue of Arsenic and Lead-induced nephrotoxicity and hepatotoxicity in rats. Hence, E. officinalis and Z. officinalae leaf extract are potential therapeutic options for the treatment of metal toxicity-induced kidney and liver diseases.

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Shuja, Naveed, Nabeela Zeeshan, Shahnaz Bano Memon, Asad Ali Zardari, Bakhtawar Mateen, Alina Saqib, Ihsan Ullah Khan et Arslan Shuja. « The Treatment of Hexavalent Chromium Induced Ovarian Cancer in Albino Rats with Emblica Officinalis. A Comparative Study ». Pakistan Journal of Medical and Health Sciences 16, n^o 12 (31 décembre 2022) : 450–53. http://dx.doi.org/10.53350/pjmhs20221612450.

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Background: Ovarian cancer may be treated with medicinal herbs like extract from Emblica officinalis Phytochemicals of this herb have antioxidant efficacy against oxidants and reduce cellular as well as genotoxicity. Aims and objectives: In current study hexavalent chromium induced ovarian cancer in albino rats were treated with emblica officinalis extract through a piolet project and measured its efficacy with the passage of time. Research Design: A comparative study of medicinal herbs, Emblica officinalis against ovarian cancer. Population Sampling: In this study female albino rates of about 100 gram body weight were selected comparatively. Sample Size: 15 female albino rates about equal weight were selected and divided them into different groups. Place and Duration: Present study was conducted from January 2022 to June 2022 at animal house of IMBB the University of Lahore and Biochemistry Department of Lahore Medical & Dental College Lahore Pakistan. Methodology: Total 15 female albino rates were selected in this study and divided them into different groups. In Group-A which is control all individuals were normal and not treated with anything. In Group-B and Group-C there were 5 rates in each group and they were treated with different strength of Emblica officinalis extract in distil water. Results: It has seen that the blood serum levels of CA-125, Alpha-fetoprotein and Lactate dehydrogenase in both group-B and group-C presented in table-2, table-3, table-4 and table-5 showed a remarkable significant changes (P≤0.05) after intervals of time. The significant changes in blood serum levels of CA-125, Alpha-fetoprotein and Lactate dehydrogenase (37±0.01, 42±0.01, 341±0.01) were noted in group-C individuals how were treated with 10mg/body weight ethanolic extract of Emblica officinalis for two month as compared to the control group-A. Practical implication Conclusion: The significant changes in blood serum levels of CA-125, Alpha-fetoprotein and Lactate dehydrogenase (37±0.01, 42±0.01, 341±0.01) were noted in group-C individuals how were treated with 10mg/body weight ethanolic extract of Emblica officinalis for two month as compared to the control group-A. Keywords: Alpha-fetoprotein, Lactate dehydrogenase, Emblica officinalis, Hexavalent Chromium

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N, Gunavathy, et Subarna A. « CHEMICAL CHARACTERIZATION OF THE ACTIVE CONSTITUENTS PRESENT IN DIFFERENT FORMS OF EMBLICA OFFICINALIS (AMLA) ». Kongunadu Research Journal 1, n^o 2 (30 décembre 2014) : 58–64. http://dx.doi.org/10.26524/krj39.

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The chemical characteristics of different forms of Emblica officinalis - fresh amla, sweet amla, dried amla, salted amla and lehyam - were analyzed for total phenol, vitamin C, carbohydrate, fat and total antioxidant capacity. The ash of the respective samples was used to determine the iron, calcium and phosphorus content. Higher percentage of total antioxidant capacity was observed in all the samples, which depends on the concentration of the phenolic compounds. In conclusion it can be stated that the vitamin C content (361.90mg/100g) and iron content (0.012mg/100mg) were higher in fresh form of Emblica officinalis whereas dried amla showed higher level of phosphorus (0.14%), phenolic acids (10%) compared to all other form of Emblica officinalis.

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JOSE, Jeena K., et Ramadasan KUTTAN. « Antioxidant Activity of Emblica officinalis. » Journal of Clinical Biochemistry and Nutrition 19, n^o 2 (1995) : 63–70. http://dx.doi.org/10.3164/jcbn.19.63.

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Jose, Jeena K., Girija Kuttan et Ramadasan Kuttan. « Antitumour activity of Emblica officinalis ». Journal of Ethnopharmacology 75, n^o 2-3 (mai 2001) : 65–69. http://dx.doi.org/10.1016/s0378-8741(00)00378-0.

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S., Sangeetha, Malay K. Samanta, Kavitha R., Remya P. N. et Saraswathi T. « FORMULATION AND PHARMACOKINETIC DETERMINATION OF GALLIC ACID IN EMBLICA OFFICINALIS ». International Journal of Applied Pharmaceutics 9, n^o 5 (15 septembre 2017) : 9. http://dx.doi.org/10.22159/ijap.2017v9i5.16011.

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Objective: The present work was to formulate oral herbal tablets of Emblica officinalis extract and also with pure gallic acid, further to determine the dosage frequency through pharmacokinetic profiles obtained for the same.Methods: The Emblica officinalis fruits were suitably extracted and the concentration of gallic acid in Emblica officinalis extract was estimated by HPTLC (High-Performance Thin Layer Chromatography) with a comparison to pure form. Tablets were prepared with extract and synthetic form through direct compression technique by varying the process and formulation parameters. The formulated tablets were administered to rabbit models and their pharmacokinetic profile was studied after withdrawing blood samples through HPLC (High-Performance Liquid Chromatography).Results: The concentration of gallic acid in Emblica officinalis was found to be 8.21%. The pre and post compression parameters evaluated for the formulated batches found to be within the pharmacopoeial limits. The in vivo pharmacokinetic studies conducted in rabbit models showed that there were no significant differences with p-value between the pharmacokinetic data obtained for pure and extract gallic acid tablets. The Cmax was found to be 4.59±0.95 µg/ml in the extract form which was little low when compared to the pure form of 6.38±1.08 µg/ml. The t1/2 in the extract form was 6.0±0.33 h, whereas it was 4.92±0.36 h in the pure form of gallic acid.Conclusion: The Emblica officinalis extract tablet showed average t1/2 of 6 h, so about every 6 h one tablet compared to 4 h of t1/2 for pure gallic acid tablet can be the dosing frequency for the rabbit.

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Khanam, Khadiza, Sultana Rajia, A. H. M. Mostofa Kamal, Md Sarwar Jahan, Md Aziz Abdur Rahman, A. H. M. Khurshid Alam et Mamunur Rashid. « Linagliptin in Combination with Emblica officinalis Gaertn Improves Glycemic Control through Alleviating Dyslipidemia and Oxidative Stress on Streptozotocin Induced Diabetic Rats ». Journal of Pharmaceutical Research International 35, n^o 12 (19 mai 2023) : 37–46. http://dx.doi.org/10.9734/jpri/2023/v35i127363.

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Objectives: Diabetes is a complex chronic metabolic disorder. Today, many diabetes patients are known to supplement their standard therapies with herbal medications that have antidiabetic characteristics. The purpose of the study was to examine the fixed dose combination of linagliptin and Emblica officinalis Gaertn (aq FE) for its hypoglycemic, hypolipidemic, and antioxidant properties. Methods: Streptozotocin (45 mg/kg b.w.) was administered intraperitoneally to Wister albino rats to cause diabetes. Linagliptin (5 mg/ 70kg b.w), aqueous fruit extract of Emblica officinalis Gaertn (200 mg/kg b.w.) and fixed dose combination therapy of linagliptin (2.5 mg /70kg b.w) with aqueous fruit extract of Emblica officinalis Gaertn (100 mg/kg b.w) were administered orally once daily for four weeks. After that fasting blood glucose level (FBG), low density lipoprotein (LDL), high density lipoprotein (HDL), total cholesterol (TC) and triglycerides (TG) were measured in serum with streptozotocin (STZ)-induced diabetes. Typical procedures were used to measure the antioxidant activity by the estimation of catalase (CAT) and superoxide dismutase (SOD) activity. Results: The combination therapy significantly (p<0.05) reduced the FBG, TC, TG, LDL level in compared to the diabetic control group (p<0.05). Significant (p<0.05) increased of HDL was also observed. The antioxidant activity significantly increased after the administration of fixed dose combination therapy in compared to diabetic control group. These alterations were vastly superior to those of linagliptin with Emblica officinalis Gaertn (aqFE) monotherapy. Conclusion: This study suggests that the fixed dose combination therapy of linagliptin and Emblica officinalis Gaertn (aq FE) might be potent on antihyperglycemic antidyslipidemic and antioxidative effect.

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Zulfiqar, Hadia, Muhammad Suhail, Amna Rehman, Afifa Waseem, Faeza Rauf et Hafiza Sadia Ahmed. « Emblica officinalis Reduces Copper Mediated Inflammation And Preserves Liver Morphology InThe Murine Model ». Proceedings 37, n^o 3 (31 juillet 2023) : 28–33. http://dx.doi.org/10.47489/szmc.v37i3.377.

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Introduction: Copper (Cu) is a metal widely used in agriculture and in industries. Its hepatotoxicity is established in literature. Emblica officinalis, locally known as Amla, has many beneficial health effects and is scientifically reported to be a powerful antioxidant. Aim & Objective: To determine the role of Emblica officinalis fruit in reducing Cu induced inflammation and distortion of hepatic lobules of adult albino rats. Place and duration of Study: The study was done in the Department of Anatomy, Shaikh Zayed Medical College, Lahore for a period of 4 weeks. Material & Methods: 36 Adult male albino rats were equally divided into three groups (A, B, C) by randomization and acclimatized for 1 week. 1.5 ml of normal saline was given to rats of Group A (control) and CuSO4 (200mg/kg b.w./day) was given to those in group B (Cu treated) once daily via orogastric tube. Rats in group C (Cu+EO treated) were given both CuSO4 (200mg/kg bw) and Emblica officinalis fruit extract (300mg/kg bw) once daily by orogastric intubation. The animals were sacrificed after 28 days and livers were dissected out for histological study. Data was entered and analyzed using SPSS version 22. Results: Cu treated rats developed significant distortion of liver architecture and inflammation while Emblica officinalis co-treatment lead to decreased inflammation with preservation of shape of hepatic lobule. These findings were further confirmed by difference in diameters of hepatic lobules between control, Cu-, Cu+EO- treated groups. Conclusion: Emblica officinalis, by limiting oxidative damage, ameliorates hepatic inflammation and preserves liver architecture. Therefore, its use as a hepatoprotective agent should be encouraged.

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Rachitha, Puttasiddaiah, Krupashree Krishnaswamy, Renal Antoinette Lazar, Vijai Kumar Gupta, Baskaran Stephen Inbaraj, Vinay Basavegowda Raghavendra, Minaxi Sharma et Kandi Sridhar. « Attenuation of Hyperlipidemia by Medicinal Formulations of Emblica officinalis Synergized with Nanotechnological Approaches ». Bioengineering 10, n^o 1 (4 janvier 2023) : 64. http://dx.doi.org/10.3390/bioengineering10010064.

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The ayurvedic herb Emblica officinalis (E. officinalis) is a gift to mankind to acquire a healthy lifestyle. It has great therapeutic and nutritional importance. Emblica officinalis, also known as Indian gooseberry or Amla, is a member of the Euphorbiaceae family. Amla is beneficial for treating illnesses in all its forms. The most crucial component is a fruit, which is also the most common. It is used frequently in Indian medicine as a restorative, diuretic, liver tonic, refrigerant, stomachic, laxative, antipyretic, hair tonic, ulcer preventive, and for the common cold and fever. Hyperlipidemia is also known as high cholesterol or an increase in one or more lipid-containing blood proteins. Various phytocompounds, including polyphenols, vitamins, amino acids, fixed oils, and flavonoids, are present in the various parts of E. officinalis. E. officinalis has been linked to a variety of pharmacological effects in earlier studies, including hepatoprotective, immunomodulatory, antimicrobial, radioprotective, and hyperlipidemic effects. The amla-derived active ingredients and food products nevertheless encounter challenges such as instability and interactions with other food matrices. Considering the issue from this perspective, food component nanoencapsulation is a young and cutting-edge field for controlled and targeted delivery with a range of preventative activities. The nanoformulation of E. officinalis facilitates the release of active components or food ingredients, increased bioaccessibility, enhanced therapeutic activities, and digestion in the human body. Accordingly, the current review provides a summary of the phytoconstituents of E. officinalis, pharmacological actions detailing the plant E. officinalis’s traditional uses, and especially hyperlipidemic activity. Correspondingly, the article describes the uses of nanotechnology in amla therapeutics and functional ingredients.

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Kumar, Yogesh, Anita Thakur et Tarun Kumar Thakur. « Performance of wheat crop under different tree crop combination of a land use system ». Ecology, Environment and Conservation 28, n^o 04 (2022) : 1920–24. http://dx.doi.org/10.53550/eec.2022.v28i04.040.

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Agri-horti-silviculture system of agroforestry are very suitable to marginal or small farmers. The basic needs of food, fodder, fuel and timber for farmers in addition to its economic benefits can be easily fulfilled with this combination of cropping system. Among several combinations one of the suitable systems in hilly area with wheat, aonla and sissoo. A study was carried out to evaluate the performance of wheat as under storey crop with different proportion of tree combinations. Five treatments viz. 100% Emblica officinalis, 75% Emblica officinalis + 25% Dalbergia sissoo, 50% Emblica officinalis + 50% Dalbergia sissoo, 25% Emblica officinalis + 75% Dalbergia sissoo and 100% Dalbergia sissoo were selected for the study. Wheat production trend was evaluated continuously for two years from 2017-18 to 2018-19. One-year old trees were planted with desired combinations in all the treatments. Wheat variety JW-3173 was grown in all two years. Significantly highest grain yield was recorded in agroforestry (AF) with 100% Aonla (1758.25 and 1519.5 kg/ha/yr during 2017-18 and 2018-19 respectively) than all other treatments. In case of straw yield and harvest index same trend was observed during both the years. The reduction of yield was observed due to increase of canopy of tree during subsequent years.

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Jitendra Kumar Rai, Krishanu Samanta, Shweta Mishra et Jitendra Jena. « Formulation and evaluation of herbal cream using ethanolic extract of Emblica officinalis for antibacterial activity ». International Journal of Science and Research Archive 8, n^o 1 (28 février 2023) : 689–94. http://dx.doi.org/10.30574/ijsra.2023.8.1.0138.

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Skin infections occur commonly and after present therapeutic challenges to practioners due to the growing concerns regarding multidrug resistant bacterial, viral and fungal strain. The aim of present study was to formulate topical cream using Ethanolic leaves extract Emblica officinalis and evaluate In- vitro study the antibacterial activity of the ethanolic extracts of dried leaves of Emblica officinalis was determined by using the Agar cup plate method versus different bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa etc. By blending the ethanolic extract of Emblica officinalis (10 % w/w) into aqueous cream we formulated herbal cream. Formulation of herbal cream evaluation their physio-chemical properties, in vitro drug release and in vitro Antibacterial Activity against Staphylococcus aureus, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa. The herbal cream formulation A5 show better release and effective against bacterial strain

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More, Keshav Kalyan, Rajendra Maratrao Gade, Nitin Vitthal Gurav et Rupeshkumar Jagannath Chaudhari. « Phytochemical Investigation and Thin Layer Chromatography of Methanol Extract of Psoralea corylifolia and Emblica officinalis Leaves ». International Journal of Plant & ; Soil Science 35, n^o 19 (24 août 2023) : 653–63. http://dx.doi.org/10.9734/ijpss/2023/v35i193595.

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The current study focuses on phytochemical screening of Psoralea corylifolia and Emblica officinalis leaf extracts in methanol solvent. The antibacterial compounds found in both leaf extracts of Psoralea corylifolia and Emblica officinalis plants were investigated using phytochemical studies. The extracts contained flavonoids, terpenoids, tannins, alkaloids, saponins, and phenolic chemicals, according to preliminary phytochemical screening. The solvent systems of toluene: ethyl acetate: methanol (24:5:2) and chloroform: ethyl acetate: acetic acid (50:50:1) yielded the most phytochemicals from methanolic extracts of Psoralea corylifolia and Emblica officinalis plants, respectively. On TLC plates, these chemicals were separated, resulting in the discovery of different spots in both leaf extracts. The Rf values of methanol extract of P. corylifolia run under toluene: ethyl acetate: methanol (24:5:2) solvent system was 0.12, 0.19, 0.30, 0.41, 0.53, 0.65, 0.77, 0.84, 0.89, and 0.92, respectively, while Rf values of methanol leaf extract of E. officinalis run under chloroform: ethyl acetate: acetic acid (50:50:1)solvent system was 0.23, 0.31, 0.41, 0.64, 0.76 and 0.88 respectively. The results of the investigation will be used to confirm the proper identification of antibacterial fractions from P. corylifolia and E. officinalis crude plant extracts by GC-MS. The optimum solvent for extracting antibacterial components from P. corylifolia and E. officinalis leaves was methanol.

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Dr.Md.RageebMd.Usman, Dr Md RageebMd Usman, Dr GautamP Vadnere et Rohit Patil. « Prelimineary Phytochemical Analysis of EmblicaOfficinalis Seed ». Journal of University of Shanghai for Science and Technology 23, n^o 06 (19 juin 2021) : 1158–66. http://dx.doi.org/10.51201/jusst/21/05392.

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Phytochemical investigation of n-butanol extract of Emblica Officinalis Seed. This research is to check the phytochemical agent determination by various methods. A study is done to check the test for carbohydrate and protein, saponin, terpenoid, tannins, glycosides, alkaloid by the procedure performed to find the chemical observed in Emblicaofficinalis seed. Investing the phytochemicals present in the n-butanol extract of Emblica Officinalis seed by using in-vitro methods to check the phytochemical agent present or absent in the plant.

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Kalamkar, Anjali Ashokrao, Poonam I. Lal, Pankaj H. Chaudhary et Dipti B. Ruikar. « A review on Emblica officinalis gaertn ». International Journal of Pharmacognosy and Pharmaceutical Sciences 5, n^o 1 (1 janvier 2023) : 111–17. http://dx.doi.org/10.33545/27067009.2023.v5.i1b.121.

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Keserla Bhavani, Gnanavel V, Ratna B, Jayakar B, Aanandan, Natukula Praveen Kumar, Koya Prabhakar Rao et Namburi Lakshmi Anjaneya Amarbabu. « Comparative evaluation of antiulcer activity of combination of extracts of Embilica officinalis Gaertn and Musa sapientum Linn in rats ». International Journal of Research in Pharmaceutical Sciences 10, n^o 2 (23 avril 2019) : 1535–39. http://dx.doi.org/10.26452/ijrps.v10i2.821.

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The present study is to evaluate the anti-ulcer activity of methanolic extract of unripe fruits of Musa Sapientum Linn. and the fresh juice of the fruits of Emblica Officinalis Gaertn in Wistar rats. The methanolic extract unripened fruits of Musa Sapientum Linn. and the fresh juice of the fruits of Emblica Officinalis Gaertn were combined and evaluated for the gastroprotective activity by ethanol-induced model and indomethacin-induced model in rats at a dose of 25mg/kg (p.o) and 50mg/kg (p.o) respectively. Biochemical parameters like ulcer index, the volume of gastric juice, pH of gastric juice, free acidity and total acidity were studied. The unripe fruits of Musa and the fresh juice of Embilica will contain flavonoids, flavones, abscisic acid which shows a significant reduction in gastric volume, pH, free acidity, total acidity and ulcer index at the doses of 25mg/kg (p.o) and 50mg/kg (p.o). The results show that the unripe fruits 0f Musa Sapientum Linn. and fresh juice from the fruits of Emblica Officinalis Gaertn will combinedly possess greater antiulcer activity than that of the individual drugs.

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Patil, Bheemshetty S., Pallavi S. Kanthe, Chandramouli R. Reddy et Kusal K. Das. « Emblica officinalis (Amla) Ameliorates High-Fat Diet Induced Alteration of Cardiovascular Pathophysiology ». Cardiovascular & ; Hematological Agents in Medicinal Chemistry 17, n^o 1 (13 septembre 2019) : 52–63. http://dx.doi.org/10.2174/1871525717666190409120018.

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Background: Dietary high fat possibly causes oxidative stress. Also, it alters the pathophysiology of metabolically active myocardial tissues and vascular architecture. Emblica officinalis contains a potential antioxidant that counteracts oxidative stress and possibly maintains vascular integrity. Objective: To assess the effect of ethanolic extract of Emblica officinalis (EEO) on High Fat Diet (HFD) induced changes in vascular chemistry and histopathology of the cardiovascular system in male albino rats. Materials and Methods: Ethanolic extract of Emblica Officinalis (EEO) was prepared and phytochemical analysis was done. Rats were divided into four groups, having six rats in each group as follows: group 1- Control (20% fat); group 2 (20% fat+ EEO 100 mg/kg/b w); group 3 (30% fat) and group 4 (30% fat + EEO 100 mg/kg/b w). Dietary and EEO supplementation was continued for 21 days. Gravimetric and oxidative stress markers like MDA, NO, antioxidants like Vitamin C and E, and molecular marker (NOS3) were evaluated. Histopathological analysis was done on the myocardium and elastic artery along with measurement of coronary arterial wall thickness and lumen diameter. One way ANOVA was done for analysis of data. Results: High fat diet showed a significant increase in MDA, decrease of NO with unaltered NOS3 protein in rats fed with high fat diet, which indicate possible alteration of vascular pathophysiology. Supplementation of EEO showed an ameliorating effect on high fat diet induced oxidative stress. These results were further corroborated with findings of a histopathological study on the myocardium, elastic artery and coronary arterial architecture. Conclusion: Ethanolic extract of Emblica officinalis (EEO) indicates its cardioprotective efficacy against rats fed with high fat diet.

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Joshi, Abhishek, Nirmala Saini, Vishal Yadav, Rajpal Singh Udawat, Rajesh Mohta et S. C. Goswami. « An Evaluation of the Effects of the Herbal Supplements of Amla (Emblica officinalis) and Giloy (Tinospora cordifolia) on the Liver Function Parameters of Magra lambs Living in the Extensive System in Western Rajasthan's Arid Zone ». Journal of Advances in Biology & ; Biotechnology 27, n^o 1 (25 janvier 2024) : 7–12. http://dx.doi.org/10.9734/jabb/2024/v27i1675.

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The aim of this study was to determine the effect of herbal feed additives amla (Emblica officinalis) and giloy (Tinospora cordifolia) on Liver Function Test parameters of Magra lambs in the extensive management system. The experiment was performed on twenty eight magra lambs of three to four months of age under the extensive system, which were randomly distributed into four experimental groups of seven lambs in each group in a randomized block design (RBD). Herbal feed additive amla (Emblica officinalis) fruit powder with seed and giloy (Tinospora cordifolia) stem powder were supplemented at level of 1.5g/kg body weight with concentrate as oral/feed supplemented in T1 and T2 group, respectively except control group (C) and T3 in extensive management system. Group T3 were supplemented with the combination of amla (Emblica officinalis) fruit powder and giloy (Tinospora cordifolia) stem powder at the level of 0.75g/kg body weight with concentrate as oral/feed. At the end of experiment it appears that supplementation of herbal feed additives amla and giloy do not effect liver activity during the experimental period. Therefore, it can be concluded that the experiment was safe and did not cause any damage to the liver.

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More, K. K., R. M. Gade, N. V. Gurav, R. J. Choudhari et B. P. Birari. « Evaluation of Plant Extracts Against Xanthomonas Citri Causing Citrus Canker ». Journal of Plant Disease Sciences 18, n^o 1 (2023) : 53–58. http://dx.doi.org/10.48165/jpds.2023.1801.12.

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Solvents, including acetone, chloroform, distilled water, ethanol, and methanol, were used to test the antibacterial capabilities of two plants, Psoralea corylifolia and Emblica officinalis, against Xanthomonas citri subsp. citri, the major cause of citrus canker disease. Psoralea corylifolia seed extract yielded the highest extraction yield (14.50%) in methanol and the lowest in dichloromethane (9.75%), whereas Emblica officinalis extract yielded the highest extraction yield (15.75%) in methanol and the lowest (0.65%) in petroleumether solvent. Psoralea corylifolia and Emblicaofficinalis methanol extracts were reported to have potential antibacterial action against Xanthomonas citri. In vitro screening of eight plant-concentration interactions revealed various levels of toxicity to the bacterium, indicated as mean zone of inhibition of bacterial growth. At all concentrations examined, it was found that E. officinalis plant extract inhibited the test bacterium the most when compared to P. corylifolia plantextract.

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Arbade, Gajanan Kashinathrao, Vikram Kumar, Vidisha Tripathi, Aishwarya Menon, Suryasarathi Bose et T. Umasankar Patro. « Emblica officinalis-loaded poly(ε-caprolactone) electrospun nanofiber scaffold as potential antibacterial and anticancer deployable patch ». New Journal of Chemistry 43, n^o 19 (2019) : 7427–40. http://dx.doi.org/10.1039/c9nj01137d.

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Reddy, M. Chirag, K. N. Sreenivas, G. S. Manjula, M. Karan et H. Mohamad Tayeeb Ulla. « Aonla (Emblica officinalis Gaertn.) Based Fermented Beverages ». International Journal of Current Microbiology and Applied Sciences 6, n^o 10 (20 octobre 2017) : 4740–49. http://dx.doi.org/10.20546/ijcmas.2017.610.440.

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Kumar, Uttam, SK Jain, Shalini Pilania et PS Champawat. « Drying characteristics of aonla (Emblica officinalis) pomace ». International Journal of Chemical Studies 9, n^o 1 (1 janvier 2021) : 1738–40. http://dx.doi.org/10.22271/chemi.2021.v9.i1y.11476.

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Морозова, Ю. А., Д. С. Дергачев et М. А. Суботялов. « Компонентный состав и биологическая активность Emblica officinalis ». Растительные ресурсы 55, n^o 2 (2019) : 170–85. http://dx.doi.org/10.1134/s0033994619020067.

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Jose, Jeena K., et Ramadasan Kuttan. « Hepatoprotective activity of Emblica officinalis and Chyavanaprash ». Journal of Ethnopharmacology 72, n^o 1-2 (septembre 2000) : 135–40. http://dx.doi.org/10.1016/s0378-8741(00)00219-1.

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Murthy, Z. V. P., et Dhruv Joshi. « Fluidized Bed Drying of Aonla (Emblica officinalis) ». Drying Technology 25, n^o 5 (juin 2007) : 883–89. http://dx.doi.org/10.1080/07373930701370290.

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Dey, Anshuman, J. K. Chatterjee et Y. Vasudeva Rao. « Effect of Dietary Supplementation of Amla (Phyllanthus emblica, Syn. Emblica officinalis) on Growth and Health of Commercial Broiler Chicken (CARIBRO Dhanraja) ». International Journal of Bio-resource and Stress Management 14, Dec, 12 (22 décembre 2023) : 1608–16. http://dx.doi.org/10.23910/1.2023.4941a.

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The present research work was performed at Rathindra Krishi Vigyan Kendra, Palli Siksha Bhavana (Institute of Agriculture), Visva-Bharati, Sriniketan, Birbhum, West Bengal, during February–April 2022. The objective of the present study was to explore the effect of dietary supplementation of amla (Emblica officinalis) on the health and growth of broiler chicks (CARIBRO Dhanraja). A total of thirty-six (36) one-day old chicks were randomly distributed into three dietary treatment groups with three replicates for each treatment group and four birds in each replicate to conduct the proposed study. The three experimental dietary treatments were, Control group, fed with standard diet, i.e., without amla (E. officinalis) supplementation (T1), Test groups, fed with 1.5% amla (E. officinalis) supplemented diet (T2) and 2.5% amla (E. officinalis) supplemented diet (T3). From the results, the highest average body weight, highest weekly average body weight gain and better Feed Conversion Ratio were observed in T2 followed by T3. It was found that serum SGPT/ALT, SGOT/AST and ALP levels were found to be highest in the control group (T1), and were significantly reduced in amla-supplemented groups, least levels were observed in the T3 group. There was no significant difference observed in dressing yield among the treatments. However, in some carcass parameters, a significant difference was observed among the groups with different treatments. From the above study, it could be concluded that feed supplemented with amla (E. officinalis) improved the health and growth of the broiler chicken, which is economically profitable to the poultry farmers.

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Savadi, Dr B. S. « In Vitro Antioxidant study of Amalaki (Emblica officinalis) ». AVISHKARA 01, n^o 02 (2022) : 03–06. http://dx.doi.org/10.56804/avishkara.2022.1202.

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Background: Amalaki (Emblica officinalis) which is used to cure a number of ailments & considered as Amrutphala (life giving fruit). Amalaki is best potent herb rich with antioxidant. Objective: The present study to assess the antioxidant assays, by 2-diphenyl-1- picrylhydrazyl (DPPH) standard protocol method. Materials and Methods: Study Setting: ACRL SJGAMC&H Koppal. Amalaki (Emblica officinalis) was procured from SJG Ayurveda Medical College Pharmacy Koppal, Karnataka, India, and was subjected to Antioxidant study by DPPH standard protocol method. Results: It was observed that Amalaki indicated excellent antioxidant activity when compared to standard Ascorbic acid with the IC50 value of 77.52 and 64.5 respectively. Conclusion: These results clearly indicate the antioxidant potentials of Amalaki proving its medicinal efficacy.

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Deshmukh, Chinmay Devidas. « PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF EMBLICA OFFICINALIS LINN ». Journal of Medical pharmaceutical and allied sciences 10, n^o 2 (15 mai 2021) : 2698–703. http://dx.doi.org/10.22270/jmpas.v10i2.1054.

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Emblica officinalis (EO) (Family: Euphorbiaceae) , commonly called Amla, is a traditional plant, occurring commonly in deciduous forests in India and widely used globally for the management of various ailments. When its phytochemistry is studied in detail, it reveals the presence of vitamin C, ellagic acid, gallic acid, phyllemblin, tannin, phyllemblic acid, lipids and emblicol. The fruit of this plant is commonly used for a cooling, diuretic, laxative activity. It is also used for the treatment of anemia, jaundice and dyspepsia. The seeds are used for the management of different respiratory tract disorders such as bronchitis, asthma, and digestive problems. Various scientists and researchers have isolated the parts of this plant for studying its pharmacological activities and therapeutic approaches. They have explored this plant for its hepatoprotective, gastroprotective, cytoprotective, antitumor, antifungal and antiulcer activity. Further, this plant is also claimed to have other beneficial effects in Ayurveda and traditional medicines. This plant is common and widely available. It is consumed by various Indian people routinely. It is important ingredient of cosmetics, shampoos, hair oils, dyes and famous health tonic Chyavanprash. Though, various literature is available on this plant and fruit but due to interest and curiosity to further explore the information of its uses, chemical composition, pharmacological activities of extract and its isolated compounds and safety profile, the present review paper is planned. This information will be useful for further research of this plant.

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POORANI, J., et R. THANIGAIRAJ. « A new species of Scymnus Kugelann (Coleoptera : Coccinellidae) predatory on amla aphid, Schoutedenia emblica (Patel &amp ; Kulkarni) (Hemiptera : Aphididae), from India ». Zootaxa 5239, n^o 3 (10 février 2023) : 421–30. http://dx.doi.org/10.11646/zootaxa.5239.3.6.

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Scymnus (Scymnus) hodeki sp. n. (Coleoptera: Coccinellidae) is described and illustrated from Tamil Nadu, South India. It appears to be a specific predator of the aphid, Schoutedenia emblica (Patel & Kulkarni) (Hemiptera: Aphididae), a major pest of Indian gooseberry (Emblica officinalis Gaertn.). Notes on the life stages, biology, and natural enemies of the new species are also provided and illustrated. Other predators of the aphid are also listed and illustrated.

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Singh, Ranjan, et Suhas Kumar. « Study on correlation of Antioxidant activities with presence of phenolic and Flavanoid contents in Emblica officinalis and Terminalia chebula ». Journal of Drug Delivery and Therapeutics 11, n^o 1 (15 janvier 2021) : 32–35. http://dx.doi.org/10.22270/jddt.v11i1.4667.

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Background: Reactive oxygen species have been known to cause cellular damages that have been implicated to be a causal of major diseases; therefore natural antioxidants have shown a significant impact on human robustness. The present study was carried out to appraise the anti-oxidant activities (In- vitro) and their correlation with presence of Flavanoid and Phenolic content in fruits of Terminalia chebula and Emblica officinalis fruit extracts which is common in herbal Kitchen of India. Methods: The 70% extracts of fruits from Terminalia chebula and Emblica officialis were applied for the study of Anti-oxidant activity. Scavenging radical ability of extracts of these extracts were judged by radical like DPPH. Results: The capability of the extracts of Fruits in exhibiting Antioxidative properties follow the sequence of Terminalia chebula > Emblica officinalis. Since the antioxidant activities were studied in comparison with the standards of Flavanoid, Phenolic and Ascorbic acid. The Flavanoid and Phenolic quantity / amount along with subsequent dilution of Ascorbic acid as in case of DPPH radical assay were assessed as 127.60 ± 0.001 mg/ml, 133.00 ± 0.003 mg/ml for Phenolic Content as Gallic acid equivalent per 100 mg of the Fruit extract. Keywords: Antioxidant, Phenol, Flavanoid, Emblica, Terminalia.

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Prakash, Dhan, Garima Upadhyay et P Pushpangadan. « Antioxidant Potential of Some Under-Utilized Fruits ». Indo Global Journal of Pharmaceutical Sciences 01, n^o 01 (2011) : 25–32. http://dx.doi.org/10.35652/igjps.2011.03.

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To identify their potential sources extracts of some fruits and their different parts were studied for total phenolic contents (TPC), antioxidant (AOA) and free radical scavenging activities (FRSA). Phenols have profound importance due to their biological and free radical scavenging activities. The amount of TPC varied from 10.5 to 343.2 mg/g and AOA from 20.3 to 96.7%. Fruits of Caesalpinia mexicana, Acacia auriculiformis, fruit pericarp fibres of Cocus nucifera, and fruits of Emblica officinalis were found to have high TPC (73.1-343.2 mg/g) and high AOA (68.5-96.7%). Promising fruits were studied for their FRSA and reducing power (RP) measured by DPPH assay where the fruits of Caesalpinia mexicana, fruit pericarp fibres of Cocus nucifera, fruits of Emblica officinalis showed very low IC50 ranging from 0.009 to 0.016 mg/ml, EC50 from 0.39 to 0.70 mg/mg DPPH and reasonably high values (142.1- 256.3) of anti radical power (ARP), indicating their strong FRSA and reducing power (RP) as evident by their low ASE/ml values (0.42- 1.08). They also showed better inhibition of lipid peroxidation measured by using ferric thiocyanate assay and by using egg yolk compared to reference standard, quercetin. The ferrous and ferric ion chelating capacity of the promising fruits and their underutilized parts in terms of IC50 varied from 0.12 (Emblica officinalis, fruits) to 2.44 mg/ml (Mangifera indica, Seed kernel) and 0.22 (Caesalpinia mexicana, fruits) to 2.59 mg/ml (Litchi chinensis, fruit peel) respectively. Fruit of Acacia auriculiformis, Caesalpinia mexicana, Emblica officinalis, fruit pericarp fibres of Cocus nucifera, were also assayed for their specific phenolic composition through HPLC where the amount of caffeic acid varied from 48.5 to 2231 µg/g, chlorogenic acid 63.8 to 912.1 µg/g, ellagic acid 46.4 to 1429.1 µg/g, ferulic acid 36.7 to 762.9 µg/g, gallic acid 181.6 to 2831.6 µg/g, protocatechuic acid 41.7 to 322.8 µg/g, and quercetin 44.6 to 367.6 µg/g. © 2011 IGJPS. All rights reserved

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Rashid, Md Jabir Ben, Md Ruhul Amin, Sharmin Salam, Md Saiful Islam et Sultana Ferdousi. « Memory protective effect of Phyllanthus emblica against scopolamine induced spatial memory loss in male Long Evan Rats tested by Radial Arm Maze ». Journal of Bangladesh Society of Physiologist 17, n^o 2 (9 mai 2024) : 101–10. http://dx.doi.org/10.3329/jbsp.v17i2.72056.

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Background: Dementia is the commonest problem of middle aged and elderly subjects due to age related changes and oxidative stress. Many traditional herbal agents including Emblica Officinalis (Phyllantus Emblica) demonstrated its benefit against memory loss. Objective: To investigate the protective effect of Ethanolic extract of Phyllantus Emblica (EEPE) or Emblica Officinalis in scopolamine induced memory impaired male Long Evan rats. Methods: This animal behavioral study was carried out on total 18 male long Evan rats weighing 300-400gm. According to treatment they were divided into NS (control) group (n=6, normal saline 5ml/kg) Sco(n=6; Scopolamine 2mg/kg) and PE(n=6; EEPE 400mg/kg+ Scopolamine 2mg/kg).This experiment was conducted for total 33 days. After 7 days acclimatization NS group and PE rats were treated with normal saline and EEPE respectively for consecutive 26 days. Scopolamine was given to sco group and PE group from day 22 to 26 (5 days during acquisition phase. Spatial memory (working and reference memory error) was assessed by 8 arm radial arm maze (RAM). Statistical analysis was done by ANOVA followed by Bonferroni’s post hoc test. Result: Working memory error (WME) as well as reference memory error (RME) was found significantly higher in scopolamine treated rats compared to normal memory as well as PE pretreated rats whereas no significant difference was found in WME and RME between normal memory rats and PE pre- treated rats. Conclusion: Phyllanthus Emblica can prevent memory impairment in scopolamine induced memory loss in Long Evan rats. J Bangladesh Soc Physiol 2022;17(2): 101-110

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Tyagi, Meenakshi, et S. S. Dhawan. « Development of Osmotic Dehydrated Aonla (Emblica officinalis, Gaertn) ». International Journal of Current Microbiology and Applied Sciences 6, n^o 11 (10 novembre 2017) : 1369–74. http://dx.doi.org/10.20546/ijcmas.2017.611.163.

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JOSE, Jeena K., Girija KUTTAN, Josely GEORGE et Ramadasan KUTTAN. « Antimutagenic and Anticarcinogenic Activity of Emblica officinalis Gaertn. » Journal of Clinical Biochemistry and Nutrition 22, n^o 3 (1997) : 171–76. http://dx.doi.org/10.3164/jcbn.22.171.

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Gandhi, Yashika, Jyotika Grewal, Vipin Jain, Hemant Rawat, Sujeet K. Mishra, Vijay Kumar, Ravi Kumar et al. « Emblica officinalis : A promising herb confining versatile applications ». South African Journal of Botany 159 (août 2023) : 519–31. http://dx.doi.org/10.1016/j.sajb.2023.06.041.

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M L, Choudhary, Verma I M, Jitendra Singh, Atul Chandra et Godara S L. « Storability Studies of Aonla (Emblica officinalis Gaertn.) Syrup ». Madras Agricultural Journal 99, JUNE (2012) : 403–6. http://dx.doi.org/10.29321/maj.10.100098.

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With a view to develop value added products, from aonla cultivar NA-7, syrup was prepared under different treatments. The prepared syrup was kept at ambient condition for storage study. The syrup remained acceptable upto 240 days at ambient condition. The syrup prepared from T-3 (35 per cent juice, 65 per cent TSS and 1.3 per cent acidity) recorded maximum organoleptic score than other recipe treatments. The biochemical composition in aonla syrup prepared from T-6 (50 per cent juice, 65 per cent TSS and 1.3 per cent acidity) had the maximum retained acidity, TSS, total sugar, reducing sugar than rest of the treatments and their increasing trend with advancement of storage period upto 240 days was recorded under ambient condition. On the other hand, the syrup prepared with T-6 (50 per cent juice, 65 per cent TSS and 1.3 per cent acidity) had maximum ascorbic acid, non-reducing sugar and organoleptic score and these traits showed decreasing trend with increasing storage period upto 240 days under ambient condition. The syrup prepared from T-3 (35 per cent juice, 65 per cent TSS and 1.3 per cent acidity) had the maximum benefit: Cost ratio, high sensory evaluation score and high nutritional quality.

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Sawicka, Barbara, Barbara Krochmal-Marczak et Bernadetta Bienia. « Rośliny lecznicze występujące w południowej części Indii ». HERBALISM 4, n^o 1 (8 décembre 2021) : 86–100. http://dx.doi.org/10.12775/herb.2018.008.

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Omówiono i opisano wybrane gatunki znajdujące się zarówno w stanie naturalnym, jak i w uprawie, spośród 7500 roślin leczniczych występujących na terenie Indii – prawdziwego emporium roślin leczniczych i aromatycznych. W codziennym użyciu są tam takie gatunki jak: Azadirachta indica, Cardiospermum halicacabum, Erythrina indica, Gloriosa superba, Jatropha curcas, Moringa oleifera, Phyllanthus amarus, Ssbania grandiflora, Tamarindus indica, Tridax procumbens i Vitex negundo. Najczęściej zaś uprawiane są: Aloe vera, Azadirachta indica, Curcuma longa, Emblica officinalis, Eukaliptus tereticornis, Gloriosa superba, Moringa oleifera, Ricinus communis, Sesamum indicum, Ssbania grandiflora, Solanum americanum, Tamarindus indica i Zingiber officinale. Określono też ich wartość użytkową.

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Elumalai, Nandhakumar, Purushothaman Ayyakkannu, Shanthi Palanivelu et Sachdanandam Panchanadham. « In vitro antioxidant potential of Shemamruthaa (a herbal formulation) and its anticancer activity in the MCF-7 cell line ». RSC Advances 5, n^o 30 (2015) : 23125–33. http://dx.doi.org/10.1039/c4ra12346h.

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The current study investigates the free radical scavenging activities of methanolic and aqueous extracts of Shemamruthaa (Hibiscus rosa sinensis, Emblica officinalis and honey in definite ratio) and their anticancer activity in the breast cancer (MCF-7) cell line ex vivo.

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Shuja, Naveed, Mashkoor Ahmed Ansari, Qamar Zaman Phull, Jawad Mumtaz Sodhar, Arslan Shuja et Majida Maqsood. « Antineoplastic Mechanism of Emblica Officinalis Against Breast Cancer, A Humans Clinical Cross Sectional Study ». Pakistan Journal of Medical and Health Sciences 16, n^o 2 (26 février 2022) : 502–4. http://dx.doi.org/10.53350/pjmhs22162502.

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Current study was found that there is a significant changes (<0.005) were observed in both groups regarding reoccurrence of malignancy by considering their MRI and bone scan with passage of time. There were 70 women with breast cancer in Group B and 30 in Group A. 10 g/day emblica officinalis extract was given to the individuals of group B orally for two years their preoperative and Postoperative levels of MRI and bone scan mean standard deviation were (1.81±0.1),(clear) and (0.00±0.00.00±0.0, 0.00±0.0, 0.00±0.0), (clear, all) after 6,12,18 and 24 months respectively, while in Group A, there were 30 women with breast cancer their preoperative and postoperative levels MRI and bone scan mean standard deviation levels were (1.91±1.1), (clear) and (0.12±0.0, 0.70±0.1, 0.93±0.2, 1.00±0.0), (clear, all) after 6,12,18 and 24 months respectively. Keywords: BRCA1, BRCA2, Emblica officinalis , ellagic acid ,

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Singamaneni, Venugopal, Sudheer Kumar Dokuparthi, Nilanjana Banerjee, Ashish Kumar et Tulika Chakrabarti. « Phytochemical Investigation and Antimutagenic Potential of Ethanolic Extracts of Emblica officinalis, Terminalia chebula and Terminalia bellirica ». Natural Products Journal 10, n^o 4 (21 août 2020) : 488–94. http://dx.doi.org/10.2174/2210315509666190618101140.

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Background: Emblica officinalis Gaertn. which belongs to the family Euphorbiaceae, Terminalia chebula Retz. and Terminalia bellerica Roxb. belong to the family Combretaceae. These are well known medicinal plants with phytochemical reservoir of great medicinal values and possess a vast ethnomedical history. Objective: The aim of the present study is to isolation of major compounds and to evaluate antimutagenic potential of the ethanol extracts of these plants. Methods: The dried fruits of E. officinalis, T. bellirica and T. chebula were powdered and extracted with 95% ethanol. The ethyl acetate portions were chromatographed over silica gel to isolate major compounds. Antimutagenic activity was determined by Ames test using TA98 and TA100 strains of Salmonella typhimurium. Results: Two major known compounds, gallic acid and ellagic acid were isolated from the dried fruits of Emblica officinalis, Terminalia chebula and T. bellirica. All the three extracts counteracted the mutagenicity induced by different genotoxic compounds in a dose dependent manner. Conclusion: This study showed that ethyl acetate portion of three extracts contain two major compounds, gallic acid and ellagic acid which might be responsible for potent antimutagenic activity of these extracts.

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Kumar, S. Ranjith, K. Chozhan et K. A. Murugesh. « Determination of Bioactive compounds in the leaf extract of Phyllanthus niruri, Emblica officinalis and Psoralea corylifolia ». Journal of Ayurvedic and Herbal Medicine 8, n^o 1 (25 mars 2022) : 11–13. http://dx.doi.org/10.31254/jahm.2022.8104.

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A major part of the total populace relies upon the conventional plant based medicines. The study was carried out to determine the bioactive compounds in the botanicals viz., Phyllanthus niruri, Emblica officinalis and Psoralea corylifolia through phytochemical screening tests and to estimate the total phenol and flavonoid contents in three botanicals. The results of the phytochemical screening tests indicate the presence of phenols, tannin, flavonoids, saponins, terpenoids, steroids and alkaloids. Phytochemicals from medicinal plants/some botanicals are likely to possess many pharmacological activities such as antioxidant, anti-inflammatory, anti-cancer, antimicrobial effects against various pathogens. The Total Phenol content in Phyllanthus niruri is 115 mg/g and with flavonoid value 70.15 mg/g. The Flavonoid content in Emblica officinalis was found to be 22.52 mg/g. The value varies from plants to plants and the results clearly indicate that plants are rich in various phytochemicals components and it will be more advantage to use these botanicals as natural medicine compared with chemical drugs.

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Mahto, Binay Kumar, Rakesh Patel, Rajendra Bapna et Ajay Kumar Shukla. « Development and Standardization of a Poly Herbal Formulation ». Scientific Temper 13, n^o 02 (12 décembre 2022) : 118–25. http://dx.doi.org/10.58414/scientifictemper.2022.13.2.16.

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The traditional system of medicine requires intensive investigation in quality control tocompete with the modern medicine globally. The present research work on developmentand standardization of poly herbal capsule formulation which consist of Ocimum sanctum,Curcuma longa, Emblica officinalis, Teriminalia bellerica, Teriminalia chebula, Piper longum,Piper nigrum, and Zingiber officinale. The standardization parameters such as organolepticevaluation, powder microscopic analysis of the poly-herbal crude drugs material and physicalproperty analysis such as bulk density, tapped density; compressibility index and angle ofrepose for the formulated capsules were done. The formulated poly-herbal capsule was in theconformity to the properties evaluated and can be used as reference standard for the qualitycontrol aspect.

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Poltanov, Eugeny A., Alexander N. Shikov, H. J. Damien Dorman, Olga N. Pozharitskaya, Valery G. Makarov, Vladimir P. Tikhonov et Raimo Hiltunen. « Chemical and antioxidant evaluation of Indian gooseberry (emblica officinalis gaertn., syn. phyllanthus emblica L.) supplements ». Phytotherapy Research 23, n^o 9 (27 janvier 2009) : 1309–15. http://dx.doi.org/10.1002/ptr.2775.

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