Littérature scientifique sur le sujet « Early immune surveillance »
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Articles de revues sur le sujet "Early immune surveillance"
Schaller, Julien, et Judith Agudo. « Metastatic Colonization : Escaping Immune Surveillance ». Cancers 12, no 11 (16 novembre 2020) : 3385. http://dx.doi.org/10.3390/cancers12113385.
Texte intégralK, Geetha, et Lisa Anna Louis. « A Rare Case of Chorioangioma / Non Immune Fetal Hydrops ». Indian Journal of Obstetrics and Gynecology 11, no 3 (15 septembre 2023) : 31–34. http://dx.doi.org/10.21088/ijog.2321.1636.11323.4.
Texte intégralMitra, Roshni, Sarvjeet Singh et Ashok Khar. « Antitumour immune responses ». Expert Reviews in Molecular Medicine 5, no 3 (13 janvier 2003) : 1–22. http://dx.doi.org/10.1017/s1462399403005623.
Texte intégralFRIEDMANN, P. S., I. STRICKLAND, A. A. MEMON et P. M. JOHNSON. « Early time course of recruitment of immune surveillance in human skin after chemical provocation ». Clinical & ; Experimental Immunology 91, no 3 (28 juin 2008) : 351–56. http://dx.doi.org/10.1111/j.1365-2249.1993.tb05908.x.
Texte intégralSopper, Sieghart, Satu Mustjoki, Angelica Loskog, Bjorn T. Gjertsen, Richard Greil, Alois Lang, Werner Linkesch et al. « Immune Monitoring In Patients With Early Chronic Phase Chronic Myelogenous Leukemia (CML-CP) Treated With Frontline Nilotinib ». Blood 122, no 21 (15 novembre 2013) : 2731. http://dx.doi.org/10.1182/blood.v122.21.2731.2731.
Texte intégralBrandlmaier, Matthias, Magdalena Hoellwerth, Peter Koelblinger, Roland Lang et Andrea Harrer. « Adjuvant PD-1 Checkpoint Inhibition in Early Cutaneous Melanoma : Immunological Mode of Action and the Role of Ultraviolet Radiation ». Cancers 16, no 8 (11 avril 2024) : 1461. http://dx.doi.org/10.3390/cancers16081461.
Texte intégralUrie, Russell R., Chengchuan Xiao, Elizabeth Hughes, Elizabeth Lombard, Judy Chen, Aaron Morris, Diana Farris, Daniel Goldstein et Lonnie Shea. « Tissue Engineering Scaffolds Remotely Surveil Presymptomatic Allograft Rejection ». Journal of Immunology 210, no 1_Supplement (1 mai 2023) : 173.40. http://dx.doi.org/10.4049/jimmunol.210.supp.173.40.
Texte intégralBayó, Cristina, Gerhard Jung, Marta Español-Rego, Francesc Balaguer et Daniel Benitez-Ribas. « Vaccines for Non-Viral Cancer Prevention ». International Journal of Molecular Sciences 22, no 20 (9 octobre 2021) : 10900. http://dx.doi.org/10.3390/ijms222010900.
Texte intégralMorgado, Manuel, Ana Plácido, Sandra Morgado et Fátima Roque. « Management of the Adverse Effects of Immune Checkpoint Inhibitors ». Vaccines 8, no 4 (1 octobre 2020) : 575. http://dx.doi.org/10.3390/vaccines8040575.
Texte intégralHamatake, Kiyonori, et Kazuaki Kojima. « Initiatives for immune-related adverse events by the outpatient pharmacist clinic ». Trends in Immunotherapy 6, no 1 (10 janvier 2022) : 3. http://dx.doi.org/10.24294/ti.v6.i1.1385.
Texte intégralThèses sur le sujet "Early immune surveillance"
Pereira, Abrantes Manuela. « Hétérogénéité des neutrophiles et leurs écosystèmes dans l’immunosurveillance au cours de la tumorigenèse ». Electronic Thesis or Diss., Lyon 1, 2023. http://www.theses.fr/2023LYO10147.
Texte intégralThe neutrophil is the most abundant immune cell in the human blood that migrates rapidly to the inflammatory site. The role of neutrophils has been extensively described in infectious, autoimmune, and allergic contexts, but it remains controversial in cancer, particularly in early immune surveillance mechanisms. Neutrophils are a heterogeneous population, both phenotypically and functionally. The origin and understanding of neutrophil heterogeneity are emerging and increasingly studied, albeit to date, no study has described the evolution of neutrophil heterogeneity at different stages. The aim of my thesis is to characterize this heterogeneity within tissues during tumorigenesis, using two models. My first project focused on colorectal cancer (CRC) in humans, taking advantage of a privileged access to fresh, synchronous, and paired adjacent colorectal tissue samples (AT), preneoplastic tissues (polyps, P), and adenocarcinomas (ADK), from patients undergoing partial or total colectomies. Proteomic quantification demonstrated that neutrophils represent the main increase in the innate immune compartment within ADK. For the first time, transcriptomic profiles of FACS-sorted neutrophils and their cellular partners using RNA-seq and single-cell RNA-seq (scRNA-seq) throughout tumorigenesis were established and integrated to decipher the heterogeneity, evolution, and key cellular interactions of neutrophils in CRC. While the microenvironment of P and ADK were similar and distinct from AT, the transcriptome of P and AT neutrophils were correlated but different from ADK-associated neutrophils. These results suggest a pre-inflammatory niche in P that favors neutrophil modifications, preceding cancer-related inflammation, promoting migration and activation of myeloid cells. P-associated neutrophils exhibited functional properties (e.g. degranulation, activation, cytokine production), while ADK-associated neutrophils showed an "exhausted" state associated with a more pro-tumoral profile (i.e. loss of canonical functions and pro-tumoral profile). scRNA-seq of FACS-sorted neutrophils identified 8 distinct clusters, two of which were specifically enriched in AT and ADK. The AT-enriched cluster was associated with anti-tumoral signatures, while the ADK-enriched cluster demonstrated pro-tumoral characteristics, based on enrichment analyses of publicly available data signatures. Trajectory analyses showed a continuum from AT to P and ADK with three distinct trajectories, where a unique ADK-enriched cluster of neutrophils expressing interferon-stimulated genes stood out from the others. The second project was based on a mouse model of spontaneous mammary carcinogenesis, MMTV-NeuT, for which, unlike the human model, we have access to breast tissues at different stages as well as blood and primary (bone marrow) and secondary (spleen) lymphoid organs. Transcriptomic analysis of FACS-sorted neutrophils revealed distinct phenotypic and functional states depending on the organ and tumor stage. Interestingly, we unveiled the existence of a unique EpCAM+ neutrophil population in tumor tissues, representing 60 to 90% of total neutrophils throughout tumorigenesis. EpCAM expression was not endogenous but seemed to originate from exogenous membrane fragments on the surface of neutrophils, suggesting a mechanism of trogocytosis or even trogoptosis of preneoplastic and tumor cells. Further functional studies will elucidate the mechanism and the role of EpCAM+ neutrophils
Livres sur le sujet "Early immune surveillance"
Stewart, Alex G., Sam Ghebrehewet et Peter MacPherson. New and emerging infectious diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198745471.003.0026.
Texte intégralChapitres de livres sur le sujet "Early immune surveillance"
Alshammary, Amal F., Mashael Al-Toub, Talat Abdullah Albukhari et Waheed A. Filimban. « Cancer Surveillance ». Dans Molecular Targets and Cancer Therapeutics (Part 2), 271–341. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815124606123010009.
Texte intégralRasheed Anjum, Faisal, Sidra Anam, Muhammad Luqman, Ameena A. AL-surhanee, Abdullah F. Shater, Muhammad Wasim Usmani, Sajjad ur Rahman, Muhammad Sohail Sajid, Farzana Rizvi et Muhammad Zulqarnain Shakir. « Fungal Immunology : Mechanisms of Host Innate Immune Recognition and Evasion by Pathogenic Fungi ». Dans Fungal Reproduction and Growth [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.101415.
Texte intégralCrowcroft, Natasha, et Elizabeth Miller. « Pertussis epidemiology ». Dans Pertussis, 66–86. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198811879.003.0004.
Texte intégralMonaco, John J. « Molecular tnechanistns of antigen processing ». Dans Molecular Immunology, 211–47. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780199633791.003.0005.
Texte intégralElmaleh, David R., Matthew A. Downey, Ljiljana Kundakovic, Jeremy E. Wilkinson, Ziv Neeman et Eran Segal. « New Approaches to Profile the Microbiome for Treatment of Neurodegenerative Disease ». Dans Advances in Alzheimer’s Disease. IOS Press, 2022. http://dx.doi.org/10.3233/aiad220008.
Texte intégralActes de conférences sur le sujet "Early immune surveillance"
Zhang, Yuan, Jinyang Wang, Yi Xiao, Xiangliang Yuan, Ping Li, Yimin Duan, Victoria L. Seewaldt et Dihua Yu. « Abstract 2592 : Boosting immune surveillance by low-dose PI3K inhibitor facilitates early intervention of breast cancer ». Dans Proceedings : AACR Annual Meeting 2021 ; April 10-15, 2021 and May 17-21, 2021 ; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-2592.
Texte intégralWeygant, Nathaniel, Jiannan Yao, Dongfeng Qu, Parthasarathy Chandrakesan, Guangyu An et Courtney W. Houchen. « Abstract 2594 : A multigene recurrence signature identifies highly proliferative tumors that escape immune surveillance in early stage lung and pancreas adenocarcinoma ». Dans Proceedings : AACR Annual Meeting 2018 ; April 14-18, 2018 ; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2594.
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