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Articles de revues sur le sujet « Distance de barrière minimale »

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Auteur : Grafiati
Publié le 25 mai 2024

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1

Dedecker, Jérôme, et Clémentine Prieur. « Couplage pour la distance minimale ». Comptes Rendus Mathematique 338, no 10 (mai 2004) : 805–8. http://dx.doi.org/10.1016/j.crma.2004.03.015.

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Canillos, Thibaud. « Les bâtiments de stockage de denrées agricoles tardo-antiques de la Barrière 2 à Servian (Hérault) ». Revue archéologique de Narbonnaise 53, no 1 (2020) : 345–62. http://dx.doi.org/10.3406/ran.2020.2017.

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En 2017, la fouille préventive du site de la Barrière 2 sur la commune de Servian a permis de mettre en évidence un bâtiment antique de grandes dimensions, comportant des bases maçonnées. Celui-ci est structuré par deux murs d’orientation nord-est/ sud-ouest, cinq massifs maçonnés et huit fosses de spoliations en lien avec d’autres massifs. Ceux-ci ont la même orientation que les murs et semblent faire partie intégrante d’un même ensemble. Ce plan est incomplet, se poursuivant au sud et au nord de l’emprise de fouille. Sa superficie minimale est de 375 m ² et il a dû subir au moins une extension et/ ou une réfection. En effet, on observe des recoupements entre plusieurs de ces massifs, puis des spoliations au moment de l’abandon du site. Au moins deux états ont été documentés, le premier prenant place dans un large IVe s., alors que le second semble être abandonné à partir du milieu du Ve s. Le plan de cet édifice pourrait le rapprocher des grands greniers à piliers internes, surtout connus dans le nord de la Gaule, qui ont la particularité de posséder une superficie importante et des murs à contreforts.
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Aubry, Christophe. « Estimateur de la distance minimale en moyenne pour un modèle régulier ». Comptes Rendus de l'Académie des Sciences - Series I - Mathematics 325, no 8 (octobre 1997) : 899–902. http://dx.doi.org/10.1016/s0764-4442(97)80134-6.

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Hénaff, Sylvain. « Asymptotique de l'estimateur de distance minimale du paramètre du processus d'Ornstein-Uhlenbeck ». Comptes Rendus de l'Académie des Sciences - Series I - Mathematics 325, no 8 (octobre 1997) : 911–14. http://dx.doi.org/10.1016/s0764-4442(97)80137-1.

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Gauthier, M., J. Lebon, A. B. Tanguay et F. Bégin. « MP007 : Constats de décès à distance et disponibilité des services préhospitalier d’urgence ». CJEM 18, S1 (mai 2016) : S68. http://dx.doi.org/10.1017/cem.2016.148.

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Introduction: L’Unité de coordination clinique des services pré-hospitaliers d’urgence (UCCSPU) est un plateau clinique rattaché au CSSS Alphonse-Desjardins (CHAU Hôtel-Dieu de Lévis) qui permet un soutien médical à distance des patients transportés par ambulance dans la région de Chaudières-Appalaches (CA). En 2011, un projet novateur, devenu programme par la suite, a été instauré afin de réaliser des constats de décès à distance (CDD). Le but du programme est de réduire le nombre de transport de patients décédés vers les hôpitaux afin de remettre rapidement en service l’équipe ambulancière. Le but de l'étude est de décrire et comparer le taux de CDD et le gain de temps sur la remise en service de l’équipe ambulancière avant et après l’implantation du programme de CDD dans deux différentes régions géographiques (Chaudières-Appalaches et Saguenay-Lac-St-Jean (SLSJ)). Par la suite, déterminer s’il existe une distance minimale à partir de laquelle ce gain de temps est nul pour chaque région. Methods: Il s’agit d’une étude rétrospective portant sur 204 personnes réparties en 4 groupes : 2 groupes témoins [CA pré-CDD (50) et SLSJ pré-CDD (50)] et 2 groupes d’étude [CA post-CDD (52) et SLSJ post-CDD (52)] pour les deux régions. Le pourcentage de CDD réussi (taux de réalisation) par région et les gains de temps entre chaque groupe (intra- et inter-région) en fonction de la distance avec le centre hospitalier (CH) ont été calculés. Results: Pour un même nombre de patients, le taux de réalisation de CDD est similaire entre les deux régions [CA=80% (6 mois) et SLSJ=76% (4 mois)]. Le temps de remise en service des ambulances est différent (p<0.05) inter-région se caractérisant par des gains de temps moyens de 62 min (CA) et 28 min (SLSJ). Enfin, la distance minimale où le gain de temps est nul est de moins de 5 km pour chaque région. Conclusion: L’implantation du programme de CDD permet un gain de temps favorisant un retour plus rapide des services pré-hospitalier d’urgence si la distance entre le lieu du CDD et du CH est supérieure à 5 km. De plus, le gain en temps est proportionnel avec la distance entre le lieu du CCD et le CH.
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Kleißen, Jasmin, Niko Balkenhol et Heike Pröhl. « Landscape Genetics of the Yellow-Bellied Toad (Bombina variegata) in the Northern Weser Hills of Germany ». Diversity 13, no 12 (27 novembre 2021) : 623. http://dx.doi.org/10.3390/d13120623.

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Anthropogenic influences such as deforestation, increased infrastructure, and general urbanization has led to a continuous loss in biodiversity. Amphibians are especially affected by these landscape changes. This study focuses on the population genetics of the endangered yellow-bellied toad (Bombina variegata) in the northern Weser Hills of Germany. Additionally, a landscape genetic analysis was conducted to evaluate the impact of eight different landscape elements on the genetic connectivity of the subpopulations in this area. Multiple individuals from 15 study sites were genotyped using 10 highly polymorphic species-specific microsatellites. Four genetic clusters were detected, with only two of them having considerable genetic exchange. The average genetic differentiation between populations was moderate (global FST = 0.1). The analyzed landscape elements showed significant correlations with the migration rates and genetic distances between populations. Overall, anthropogenic structures had the greatest negative impact on gene flow, whereas wetlands, grasslands, and forests imposed minimal barriers in the landscape. The most remarkable finding was the positive impact of the underpasses of the motorway A2. This element seems to be the reason why some study sites on either site of the A2 showed little genetic distance even though their habitat has been separated by a strong dispersal barrier.
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7

Rodier, François. « Estimation asymptotique de la distance minimale du dual des codes BCH et polynômes de Dickson ». Discrete Mathematics 149, no 1-3 (février 1996) : 205–21. http://dx.doi.org/10.1016/0012-365x(94)00320-i.

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Nugraha, Priyambada Cahya, I. Dewa Gede Hari Wisana, Dyah Titisari et Farid Amrinsani. « Optimal Long Distance ECG Signal Data Delivery Using LoRa Technology ». Journal of Biomimetics, Biomaterials and Biomedical Engineering 55 (28 mars 2022) : 239–49. http://dx.doi.org/10.4028/p-6z381m.

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Cardiovascular disease is the leading cause of death in the world and the number one killer in Indonesia, with a mortality rate of 17.05%. The target of this research is to increase the range of electrocardiograph (ECG) equipment using LoRa Technology. With LoRa Technology, it is expected that the data transmission process can run effectively and produce an accurate ECG signal and minimal noise. The research method is by sending a heart signal from the ECG simulator by the microcontroller via LoRa Technology which is received by the PC (Personal Computer) and the ECG signal is displayed on the PC display. The most optimal setting will be obtained from the sender-receiver distance and baudrate by measuring data loss and delay. In this study, the simulated cardiac signal from the phantom ECG is fed to an analog signal processing circuit, then the signal is converted to digital and digitally filtered on the microcontroller, then the signal is sent via the LoRa HC-12 Transceiver to a PC with baudrate, distance and barrier settings. The results obtained are that data transmission can be carried out at a distance of 175 meters without a barrier and a distance of 50 meters with a barrier. This remote ECG equipment can detect heart signals and the results can be sent to a PC using LoRa Technology. The implication is that the transmission of ECG signal data via the Lora HC-12 Transceiver media can be carried out optimally at the 9600 baudrate setting.
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9

Boureille, Patrick. « Les relations navales franco-roumaines (1919-1928) : les illusions perdues ». Revue Historique des Armées 244, no 3 (1 août 2006) : 50–59. http://dx.doi.org/10.3917/rha.244.0050.

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À l’issue de la Première Guerre mondiale, la France espérait s’appuyer sur la Roumanie, pour contrôler les bouches du Danube, tenir à distance la Russie soviétique du cœur de l’Europe et contrôler le révisionnisme allemand. Une décennie plus tard, les relations franco-roumaines n’avaient débouché sur aucune réalité concrète. Impécuniosité notoire et rivalités entre les dirigeants roumains s’étaient conjuguées avec la refondation d’un État multinational, dans le contexte diplomatique mouvant des années 1920, pour rendre chimérique l’hégémonie française. La sécurité des frontières poussa Bucarest à rechercher une garantie formelle que Paris refusait de donner contre les irrédentismes des pays limitrophes. De son côté, la France, qui voyait dans la Roumanie une barrière contre l’URSS et une alliance de revers jusqu’en 1925, mise sur la sécurité collective après Locarno. Les concurrences britannique et italienne achevèrent de ruiner la tentative française d’établir une tutelle régionale.
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10

Hjalmarsson, Clara, Maria Ohlson et Börje Haraldsson. « Puromycin aminonucleoside damages the glomerular size barrier with minimal effects on charge density ». American Journal of Physiology-Renal Physiology 281, no 3 (1 septembre 2001) : F503—F512. http://dx.doi.org/10.1152/ajprenal.2001.281.3.f503.

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Puromycin aminonucleoside (PAN) has been suggested to reduce glomerular charge density, to create large glomerular “leaks,” or not to affect the glomerular barrier. Therefore, we analyzed glomerular charge and size selectivity in vivo and in isolated kidneys perfused at 8°C (cIPK) in control and PAN-treated rats. The fractional clearances (θ) for albumin and Ficoll of similar hydrodynamic size were 0.0017 ± 0.0004 and 0.15 ± 0.02, respectively, in control cIPKs. Two-pore analysis gave similar results in vivo and in vitro, with small- and large-pore radii of 47–52 and 85–105 Å, respectively, in controls. Puromycin increased the number of large pores 40–50 times, the total pore area over diffusion distance decreased by a factor of 25–30, and the small-pore radius increased by 33% ( P < 0.001 for all comparisons of size selectivity and θ). The effect of PAN was less dramatic on the estimated wall charge density, which was 73% of that of controls. We conclude that puromycin effectively destroys the glomerular size barrier with minimal effects on charge density.
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11

Sesay, M., P. Tauzin-Fin, F. Barbe, A. Chehab, B. Maachi, M. Penna, M. Stockle, M. Biais et K. Nouette-Gaulain. « Pollution électromagnétique de très basse fréquence au bloc opératoire : quelles sont les sources, l’intensité journalière et la distance minimale de sécurité ? » Annales Françaises d'Anesthésie et de Réanimation 33 (septembre 2014) : A151. http://dx.doi.org/10.1016/j.annfar.2014.07.252.

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12

Lorenzo, Melvin F., Sean C. Thomas, Yukitaka Kani, Jonathan Hinckley, Matthew Lee, Joy Adler, Scott S. Verbridge et al. « Temporal Characterization of Blood–Brain Barrier Disruption with High-Frequency Electroporation ». Cancers 11, no 12 (23 novembre 2019) : 1850. http://dx.doi.org/10.3390/cancers11121850.

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Treatment of intracranial disorders suffers from the inability to accumulate therapeutic drug concentrations due to protection from the blood–brain barrier (BBB). Electroporation-based therapies have demonstrated the capability of permeating the BBB, but knowledge of the longevity of BBB disruption (BBBD) is limited. In this study, we quantify the temporal, high-frequency electroporation (HFE)-mediated BBBD in an in vivo healthy rat brain model. 40 male Fisher rats underwent HFE treatment; two blunt tipped monopolar electrodes were advanced into the brain and 200 bursts of HFE were delivered at a voltage-to-distance ratio of 600 V/cm. BBBD was verified with contrast enhanced T1W MRI (gadopentetate dimeglumine) and pathologically (Evans blue dye) at time points of 1, 24, 48, 72, and 96 h after HFE. Contrast enhanced T1W scans demonstrated BBBD for 1 to 72 h after HFE but intact BBB at 96 h. Histologically, tissue damage was restricted to electrode insertion tracks. BBBD was induced with minimal muscle contractions and minimal cell death attributed to HFE. Numerical modeling indicated that brief BBBD was induced with low magnitude electric fields, and BBBD duration increased with field strength. These data suggest the spatiotemporal characteristics of HFE-mediated BBBD may be modulated with the locally applied electric field.
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Baccaïni, Brigitte. « Régions attractives et régions répulsives entre 1982 et 1990. Comparaison avec la période 1975-1982 et spécificité des différentes classes d'âges ». Population Vol. 48, no 6 (1 juin 1993) : 1791–811. http://dx.doi.org/10.3917/popu.p1993.48n6.1811.

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Résumé Baccaini (Brigitte). - Régions attractives et régions répulsives entre 1982 et 1990 : comparaison avec la période 1975-1982 et spécificité des différentes classes d'âges Les modèles dits « gravitaires » permettent d'analyser les flux migratoires en éliminant les effets déterminants de la distance entre les zones et des masses de population en présence. L'application d'un tel modèle aux migrations interrégionales françaises de la période 1982-1990, en distinguant les différentes classes d'âge a tout d'abord permis de montrer que l'impact de la distance est plus fort chez les jeunes que chez les adultes et surtout que chez les retraités. L'observation des valeurs prises par l'indice d'attraction et de répulsion, dans les différentes régions (ces indices étant calculés à partir des résidus du modèle) a révélé quelques évolutions sensibles entre les périodes 1975-1982 et 1982-1990 : pouvoir attractif croissant de l'ensemble des régions du Sud, hausse de la capacité de rétention de la région parisienne... L'analyse des «flux résiduels» a permis de mettre en évidence des «directions préférentielles » et des « effets de barrière » entre régions. Des contrastes importants sont apparus entre le comportement des jeunes, pour qui la région parisienne reste très attractive, et celui des autres classes d'âges qui ont tendance à fuir cette région pour se diriger vers celles du Sud et de l'Ouest. Les régions du quart Nord-Est (et plus particulièrement le Nord-Pas-de-Calais) sont toujours, comme au cours de la période précédente, peu attractives pour les individus originaires de la plupart des autres régions, et cela à tous les âges.
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Amat, Philippe, Carlos O’Connor-Reina et Guillermo Plaza. « Rééducation myofonctionnelle orofaciale et syndrome d’apnées obstructives du sommeil : l’apport de la santé connectée ». Revue d'Orthopédie Dento-Faciale 55, no 4 (novembre 2021) : 501–12. http://dx.doi.org/10.1051/odf/2021034.

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La rééducation myofonctionnelle orofaciale (RMOF) a été montrée efficace dans le traitement multidisciplinaire des syndromes d’apnées obstructives du sommeil (SAOS) de l’enfant, de l’adolescent et de l’adulte et elle est prescrite à plusieurs étapes de ces prises en charge. La santé connectée fait appel à l’utilisation de messages électroniques, à une surveillance à distance, à des plateformes de télémédecine du sommeil et à des applications de santé mobile. Les objets connectés aident au diagnostic du SAOS, ils permettent la télésurveillance des patients traités par pression positive continue et facilitent la prise en charge des comorbidités liées au SAOS. La première application conçue pour réaliser une RMOF chez des patients souffrant de SAOS, nommée Airway Gym®, a été conçue par O’Connor-Reina et al. en 2017. Elle permet au patient d’interagir directement avec le smartphone sans avoir besoin d’un autre appareil et elle vise à améliorer la tonicité des différents muscles impliqués dans la pathogenèse du SAOS. Un essai clinique randomisé a évalué les effets de l’application Airway Gym® chez des patients atteints de SAOS sévère, et montré des améliorations significatives de l’IAH, du score de l’échelle de somnolence d’Epworth, de la saturation minimale en O2, du score maximal de la langue IOPI et du score maximal des lèvres IOPI.
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Michel, C. C. « Oxygen Diffusion in Oedematous Tissue and through Pericapillary Cuffs ». Phlebology : The Journal of Venous Disease 5, no 4 (décembre 1990) : 223–30. http://dx.doi.org/10.1177/026835559000500403.

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The effect of oedema upon the diffusion of oxygen from capillary blood into the surrounding metabolizing tissue is considered in calculations based on the Krogh-Erlang model. While diffusion distances are increased in oedema, the oxygen consumption per unit volume of tissue is correspondingly reduced and the increments of capillary Po2 necessary to meet the tissue oxygen requirements are small. Pericapillary cuffs of oedema fluid would appear to have minimal effects on oxygen diffusion. It appears unlikely that pericapillary cuffs containing fibrin act as diffusion barriers to oxygen unless the fibrin molecules occupy more than half the volume of the cuff.
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Benziada, Mohamed Abdelghani, Ahmed Boubakeur et Abdelouahab Mekhaldi. « Polluted Barrier Effect on the Electric Field Distribution in Point-Plane Air Gaps under AC Applied Voltage : Based on Experimental Model ». ENP Engineering Science Journal 1, no 2 (31 décembre 2021) : 17–23. http://dx.doi.org/10.53907/enpesj.v1i2.21.

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The aim of this paper is to study the effect of the surface condition of an insulating barrier on the electric field distribution in point-plane air gaps with the presence of a space charge, under AC voltage. The pollution was modelled as a uniform conductive layer on the barrier surface. Electric field analysis was carried out by changing the conductivity, permittivity, and thickness of the pollution layer. Using the Finite Element Method (FEM), the geometric model has been implemented in COMSOL Multiphysics software. This method is used to solve the partial differential equations that describe the field with the presence of space charge. The electric field increases when the conductivity and thickness of the polluted layer increases. Uniform pollution on the side of the high voltage point greatly reduces the insulation quality of the barrier. In addition, a limit level of pollution, from which its minimal electric strength is equivalent to that of a conductive barrier, has been determined. This model has been validated by comparing with the experimental results of a point-barrier-plane configuration with a distance between electrodes equal to 5cm. The distribution of the electric field predicted by the numerical model is in accordance with the experimental results. The latter indicate that this model has a great contribution in the physics of discharges in the air under various polluted environments.
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Waters, Jonathan M., Tania M. King, Ceridwen I. Fraser et Dave Craw. « Crossing the front : contrasting storm-forced dispersal dynamics revealed by biological, geological and genetic analysis of beach-cast kelp ». Journal of The Royal Society Interface 15, no 140 (mars 2018) : 20180046. http://dx.doi.org/10.1098/rsif.2018.0046.

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The subtropical front (STF) generally represents a substantial oceanographic barrier to dispersal between cold-sub-Antarctic and warm-temperate water masses. Recent studies have suggested that storm events can drastically influence marine dispersal and patterns. Here we analyse biological and geological dispersal driven by two major, contrasting storm events in southern New Zealand, 2017. We integrate biological and physical data to show that a severe southerly system in July 2017 disrupted this barrier by promoting movement of substantial numbers of southern sub-Antarctic Durvillaea kelp rafts across the STF, to make landfall in mainland NZ. By contrast, a less intense easterly storm (Cyclone Cook, April 2017) resulted in more moderate dispersal distances, with minimal dispersal between the sub-Antarctic and mainland New Zealand. These quantitative analyses of approximately 200 freshly beach-cast kelp specimens indicate that storm intensity and wind direction can strongly influence marine dispersal and landfall outcomes.
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Sutama, Sutama, et Yuni Putri Indriyani. « NEWMAN ERROR ANALYSIS (NEA) : DETECTION OF STUDENT LEARNING BARRIERS IN PPKM IN MATHEMATICS SUBJECTS ». AKSIOMA : Jurnal Program Studi Pendidikan Matematika 10, no 4 (31 décembre 2021) : 2901. http://dx.doi.org/10.24127/ajpm.v10i4.4221.

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The research aims to analyze students' mistakes in solving straight-line equations and then find the learning barriers experienced during distance learning conducted in the 8th grade of a superior private junior high school in Surakarta City. The research uses qualitative descriptive design with assistive instruments in the form of three straight-line equations material test questions and interview guidelines. Triangulation used is a triangulation method and analysis data is done with the stages of data collection, data reduction, data categorization, presentation and withdrawal of conclusions. Referring to the Newman Error Analysis theory, it is identified that all five types of errors are made by students in solving straight-line equations. The five types of errors are reading errors, comprehension errors, transformation errors, process skill errors, and encoding errors. Student errors that appear to indicate obstacles in learning. The rights that arise are the ownership of mobile phones and unstable internet networks, minimal learning supervision, and the availability of fewer learning resources. The results of this study can be used as a basis for developing a learning medium that can be used and supporting online teaching.
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Koopman, Marni E., Gregory D. Hayward et David B. McDonald. « High Connectivity and Minimal Genetic Structure Among North American Boreal Owl (Aegolius Funereus) Populations, Regardless of Habitat Matrix ». Auk 124, no 2 (1 avril 2007) : 690–704. http://dx.doi.org/10.1093/auk/124.2.690.

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Abstract Habitat connectivity and corridors are often assumed to be critical for the persistence of patchily distributed populations, but empirical evidence for this assumption is scarce. We assessed the importance of connectivity among habitat patches for dispersal by a mature-forest obligate, the Boreal Owl (Aegolius funereus). Boreal Owls demonstrated a lack of genetic structure (θ = 0.004 ± 0.002 [SE]) among subpopulations, regardless of matrix type and extent, which indicates that unforested matrix does not act as a barrier to dispersal for this vagile species. We found only slightly higher genetic distances (Cavalli-Sforza chord distances ranged from 0.015 to 0.025) among patchily distributed Rocky Mountain subpopulations as compared with largely contiguous boreal-forest subpopulations (0.013 to 0.019) and no evidence of a genetic split across the expansive high plains of Wyoming. Even the most isolated subalpine patches are connected via gene flow. As northern boreal forests continue to experience intensive harvest of mature stands, geographic dispersion of Boreal Owl habitat may begin to more closely resemble that found in the Rocky Mountains. We suggest that decreased connectivity poses much less of a threat to continued abundance of this mature-forest obligate than overall loss of nesting and foraging habitat. Assessment of the importance of corridors and connectivity should be conducted on a species-by-species basis, given the variation in response of species to discontinuity of habitat, even among closely related taxa or guilds. Alta Conectividad y Estructura Genética Mínima entre Poblaciones Norteamericanas de Aegolius funereus, Independientemente de la Matriz del Hábitat
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Andhika, Adi, Ghifari Muhammad Fajri et Hendra Suroso. « ANALISIS PAPARAN RADIASI SKYSHINE DINDING RUANGAN ANGIOGRAFI/CATHLAB RUMAH SAKIT MITRA KELUARGA KEMAYORAN BERSUDUT GANTRY 0 DERAJAT ». Prosiding Seminar Si-INTAN 3, no 1 (25 octobre 2023) : 118–21. http://dx.doi.org/10.53862/ssi.v3.092023.020.

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Based on NCRP (2005), skyshine radiation generally occurs in radiotherapy facilities, the cause of which is that some radiation facilities are designed with minimal shielding on the linear accelerator (Linac) ceiling. As time goes by, Skyshine radiation monitoring is not only focused on radiotherapy facilities, but radiodiagnostic facilities also need to be monitored, especially interventional radiology, which uses real-time X-ray radiation at certain times. Regarding this matter, it is necessary to check whether the walls of the existing angiography room or cath lab are protected from skyshine radiation. This study aims to determine whether the Angiography/Cathlab room at Mitra Keluarga Kemayoran Hospital does not produce skyshine radiation. The method for measuring skyshine radiation exposure uses a survey meter at a distance of 30 cm and 2 meters 3 times from the outer wall of the Angiography/Cathlab room on the north, south, and west sides of the gantry; then the gantry is positioned at 0 degree. The research results show that radiation exposure is 0.14 µSv/hour at a distance of 30 cm. Skyshine radiation was detected at a distance of 2 meters with an exposure value of 0.32 µSv/hour on the west side of the gantry and 0.39 µSv/hour on the north side of the gantry, this occurred due to the radiation barrier wall (Pb ) not complete until the ceiling is only 2 meters high from the floor. The conclusion is that the walls of the Angiography/Cathlab room at Mitra Keluarga Kemayoran Hospital have exposure to skyshine radiation at a distance of 2 meters measured from the outer walls of the Angiography/Cathlab room on the west and north sides of the gantry of 0.32 µSv/hour and 0.39 µSv/hour. Keywords: angiography/cath lab, radiation, X-ray, skyshine, interventional radiology.
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Hadiza Gambo Rimi, Emmanuel Joseph, Dimas Skam Joseph et Dlama Zira Joseph. « Evaluation of shielding thickness in the radio-diagnostic facility of Turai Yaradua Maternity and Children Hospital Katsina, Katsina State, Nigeria ». International Journal of Science and Research Archive 9, no 2 (30 juillet 2023) : 156–62. http://dx.doi.org/10.30574/ijsra.2023.9.2.0529.

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The medical application of radiation can induce radio-biological effects which makes it necessary to ensure some safety precautions, of which, room shielding is one of those safety measures. The aim of this study was to assess the lead wall lining thickness of the radio-diagnostic room of Turai Yaradua Maternity and Children Hospital Katsina. The required lead wall lining thickness was estimated using NCRP 147 formulations. The measured area of the radio-diagnostic room was 39.44 m2. The maximum required lead thickness values were estimated as 1.1 mm and 0.8 mm for erect and supine radiographic positions, respectively, while, the installed lead wall lining thickness was 2 mm. The area monitoring revealed that there was no leakage radiation. Though, the shielding was adequate and there was no leakage radiation, it is however recommended that the radiation workers maintain maximum distance, minimum exposure time and use shielding barrier in order to ensure minimal occupational radiation exposure. Periodic area monitoring is also encouraged in order to prevent radiation exposure of the members of the public.
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Lorenzo, Melvin, Sean Thomas, Scott Verbridge, John Robertson, John Rossmeisl et Rafael Davalos. « SURG-41. BLOOD-BRAIN BARRIER DISRUPTION WITH HIGH-FREQUENCY ELECTROPORATION IN VIVO : A PRELIMINARY INVESTIGATION DEMONSTRATING THE EFFECTS OF VARIED PULSE WIDTHS AND INTRA-PHASE DELAYS ». Neuro-Oncology 22, Supplement_2 (novembre 2020) : ii212. http://dx.doi.org/10.1093/neuonc/noaa215.887.

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Abstract OBJECTIVE Treatment of CNS disorders suffer from the inability to deliver large therapeutic agents to the brain parenchyma due to protection from the blood-brain barrier (BBB). High-frequency electroporation (HFE) employs a series of high voltage pulsed electric fields to disrupt the BBB and/or ablate tumor tissue while sparring proteinaceous structures. Pulsing parameters pulse width and intra-phase delay can be modulated to reduce excitation of muscle and nervous tissues, though this is inherently accompanied by an increase in thresholds for ablation in non-CNS tissues. Here, we investigate the effects of pulse width and intra-phase delay on intracranial tissue for BBB disruption (BBBD) in an in vivo healthy rodent model. METHODS 18 male Fisher rats underwent craniectomy procedure and two blunt tipped monopolar electrodes were advanced into the brain for HFE therapy. 200 bursts of HFE were delivered at a voltage-to-distance ratio 600 V/cm. BBBD was verified with contrast enhanced T1W MRI (gadopentetate dimeglumine) and pathologically (Evans blue dye). RESULTS Gross pathological sections and contrast enhanced T1W scans demonstrated BBBD for 2-2-2 µs (n = 4, 36.6 ± 9.4 mm3, 36.7 ± 13.0 mm3), 2-5-2 µs (n = 4, 74.1 ± 7.7 mm3, 74.7 ± 9.8 mm3), 5-2-5 µs (n = 4, 53.9 ± 8.1 mm3, 59.2 ± 10.8 mm3), 5-5-5 µs (n = 4, 81.2 ± 7.9 mm3, 84.1 ± 8.7 mm3), and 10-1-10 µs (n = 2, 61.0 ± 2.8 mm3, 60.0 ± 4.2 mm3) HFE. Histologically, tissue damage was restricted to electrode insertion tracks. BBBD was induced with minimal muscle contractions and minimal cell death attributed to HFE. Numerical modeling indicated the threshold for HFE-mediated BBBD as low magnitude electric fields (&lt; 201 V/cm). These data suggest HFE-mediated BBBD is only modestly affected by changes in pulse width and intra-phase delay.
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Dumlao, Morphy, George N. Khairallah et W. Alexander Donald. « Internal Energy Deposition in Dielectric Barrier Discharge Ionization is Significantly Lower than in Direct Analysis in Real-Time Mass Spectrometry ». Australian Journal of Chemistry 70, no 11 (2017) : 1219. http://dx.doi.org/10.1071/ch17440.

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The extent of internal energy deposition using three different plasma-based ionization mass spectrometry (MS) methods, atmospheric pressure chemical ionization (APCI), direct analysis in real time (DART), and active capillary dielectric barrier discharge ionization (DBDI), was investigated using benzylammonium ‘thermometer’ ions. Ions formed by DBDI were activated significantly less than those that were formed by DART and APCI under these conditions. Thermal ion activation by DART can be reduced slightly by positioning the DART source further from the capillary entrance to the MS and reducing the heat that is applied to metastable atoms exiting the DART source. For example, the average ion internal energy distribution decreased by less than 10 % (166.9 ± 0.3 to 152.2 ± 1.0 kJ mol−1) when the distance between the DART source and the MS was increased by 250 % (10 to 25 mm). By lowering the DART temperature from 350 to 150°C, the internal energy distributions of the thermometer ions decreased by ~15 % (169.93 ± 0.83 to 150.21 ± 0.52 kJ mol−1). Positioning the DART source nozzle more than 25 mm from the entrance to the MS and decreasing the DART temperature further resulted in a significant decrease in ion signal. Thus, varying the major DART ion source parameters had minimal impact on the ‘softness’ of the DART ion source under these conditions. Overall, these data indicate that DBDI can be a significantly ‘softer’ ion source than two of the most widely used plasma-based ion sources that are commercially available.
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Isernia, Sara, Chiara Pagliari, Nuccia Morici, Anastasia Toccafondi, Paolo Banfi, Federica Rossetto, Francesca Borgnis, Monica Tavanelli, Lorenzo Brambilla et Francesca Baglio. « Telerehabilitation Approaches for People with Chronic Heart Failure : A Systematic Review and Meta-Analysis ». Journal of Clinical Medicine 12, no 1 (21 décembre 2022) : 64. http://dx.doi.org/10.3390/jcm12010064.

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Introduction: Telerehabilitation (TR) for chronic heart failure (CHF) allows for overcoming distance barriers and reducing exacerbations. However, little is known about TR descriptors, components, and efficacy in CHF. Methods: This work systematically reviewed the TR strategies of randomized controlled trials in people with CHF. A meta-analysis was run to test its effect on exercise capacity and quality of life compared to no rehabilitation (NI) and conventional intervention (CI). Results: Out of 6168 studies, 11 were eligible for the systematic review, and 8 for the meta-analysis. TR intervention was individual and multidimensional, with a frequency varying from 2 to 5 times per 8–12 weeks. The TR components mainly included an asynchronous model, monitoring/assessment, decision, and offline feedback. A few studies provided a comprehensive technological kit. Minimal adverse events and high adherence were reported. A large effect of TR compared to NI and a non-inferiority effect compared to CI was registered on exercise capacity, but no effects of TR compared to NI and CI on quality of life were observed. Conclusions: TR for people with CHF adopted established effective strategies. Future interventions may identify the precise TR dose for CHF, technological requirements, and engagement components affecting the patient’s quality of life.
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Feriyeni, Dece, et Dewi Purnamawati. « TB ASMARA CADRES IN TB CASE DISCOVERY EFFORTS AT UPT PUSKESMAS KARAWACI BARU IN 2022 ». Muhammadiyah International Public Health and Medicine Proceeding 2, no 1 (24 octobre 2022) : 63–69. http://dx.doi.org/10.61811/miphmp.v1i2.238.

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Tuberculosis (TB) is an infectious disease and is one of the leading causes of death worldwide. One of the efforts to increase coverage of active TB findings is TB screening by TB cadres. This study aims to study TB case finding with the role of ASMARA TB cadres (TB Independent Screening Application). This research is qualitative. The informants are ASMARA TB cadres at UPT Puskesmas Karawaci Baru. Data was collected through a Focus Group Discussion (FGD). of 32 cadres. The results of the study obtained 4 themes, namely Theme 1: Correct understanding of cadres about the meaning, signs, symptoms, and transmission of TB, Theme 2: Cadre's knowledge of TB Contact Investigation, Theme 3: Barriers to TB Contact Investigation, Theme 4: Obstacles Individual, Environmental and Socio-Cultural. The results showed that the Asmara TB cadres had good knowledge about TB, but it was necessary to increase knowledge continuously. Cross-sectoral cooperation is still minimal, there is a lack of public knowledge about pulmonary TB, the distance to health facilities is quite far, local cultural values and education levels are low, the role of trained cadres is not optimal, and religious leaders and the community are less involved. Continuous health education efforts are needed with cadres and community leaders to increase awareness of early detection of TB.
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Khanifah, Anisatul, et Farid Pribadi. « PERAN APLIKASI RUANG GURU DALAM MENINGKATKAN MINAT BELAJAR SISWA SAAT PANDEMI COVID-19 ». Joyful Learning Journal 11, no 3 (28 septembre 2022) : 92–99. http://dx.doi.org/10.15294/jlj.v11i3.52201.

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Covid-19 merupakan salah satu virus berbahaya yang pertama kali ditemukan di wuhan yang telah menyebar ke berbagai Negara. Sehingga Negara-negara menerapkan kebijakan Lockdown atau membatasi adanya interaksi sosial. Di era pandemi seperti saat ini beberapa sektor tidak berjalan sebagaimana mestinya, salah satunya sektor pendidikan. Pemerintah Indonesia terpaksa memberikan kebijakan agar kegiatan belajar-mengajar tetap berlangsung di masa pandemi dengan penerapan Pembelajaran Jarak Jauh yang mengandalkna platform zoom, google meet, whatsapp group dll sebagai media belajar. Dalam proses Pembelajaran jarak jauh sendiri memiliki hambatan yang kompleks dimana hal tersebut secara langsung akan mempengaruhi minat belajar siswa. Metode penelitian ini menggunakan studi literatur dimana data sekunder seperti jurnal, buku dan beberapa literasi lainnya digunakan untuk membangun konsep bahasan yang di proses melalui tahap Editing, Organizing dan finding. Penelitian ini menemukan temuan data yakni penguasaan teknologi pendidik yang masih minim, bahan ajar yang kurang menarik, Penguasaan teknologi guru di media belajar juga minim, sehingga keinginan belajar siswa terhadap mata pelajaran sendiri menurun. Ruang guru sebagai salah satu teknologi berbasis pendidikan, membuat inovasi dalam meningkatkan pembelajaran yang menyenangkan yang secara langsung membuat keinginan belajar siswa akan meningkat, melalui fitur yang ada di ruang guru, hambatan pembelajaran jarak jauh dapat diminimalisir. Maka dari itu, melalaui fitur yang ada di ruang guru siswa dapat meningkatkan keinginan belajarnya sehingga minat belajar siswa selama pandemi covid-19 akan tetap stabil. Covid-19 is one of the first dangerous viruses found in Wuhan that has spread to various countries. So that countries implement lockdown policies or limit social interaction. In the current pandemic era some sectors are not running as they should, one of which is the education sector. The Indonesian government was forced to provide a policy so that teaching and learning activities continued in the pandemic period with the implementation of Distance Learning which relied on zoom platforms, google meet, whatsapp group etc. as a learning medium. In the process of distance learning itself has complex obstacles where it will directly affect the interests of learning students. This research method uses literature studies where secondary data such as journals, books and several other literacys are used to build the concept of language that is processed through the editing, organizing and finding stages. Educator technology is still minimal, teaching materials are less attractive, mastery of teacher technology in learning media is also minimal, so that students' learning desire for their own subjects decreases. The teacher's room as one of the education-based technologies, making innovations in improving fun learning that directly makes students' learning desires will increase, through the features that exist in the teacher's room, distance learning barriers can be minimized. Therefore, through the features in the student teacher room can increase their learning desire so that students' learning interest during the covid-19 pandemic will remain stable.
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Lucas, Priscila da Silva, Milene Alves-Eigenheer, Talitha Mayumi Francisco, James M. Dietz et Carlos Ramón Ruiz-Miranda. « Spatial Response to Linear Infrastructures by the Endangered Golden Lion Tamarin ». Diversity 11, no 7 (26 juin 2019) : 100. http://dx.doi.org/10.3390/d11070100.

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Linear infrastructures are a primary driver of economic development. However, they also can negatively affect wildlife by mortality and the barrier effect. In this paper, we address how paved and unpaved roads, high-tension power lines, and gas/oil pipelines affect home range size, core areas, and movement in an endangered primate, the golden lion tamarin (GLT). Location data were recorded using radio telemetry on 16 groups in two protected areas and in privately owned forest fragments. The GLT’s home range, not core area, increased in size for the groups that occupied locations far from linear infrastructures; home range was also significantly influenced by available forest size. None of the home ranges contained a road, but home ranges did contain power lines. GLTs used the surrounding landscape near all types of infrastructure. Movement analysis showed that most of the step lengths (distances between subsequent locations) were less than 100 m between two consecutive locations, but step length was longer for roads and longer for groups in fully forested habitats. Tamarins avoided paved roads when in close proximity to this type of infrastructure; this behavior increased in areas without adequate adjacent forest habitat. Our results show that linear infrastructures differ in their level of impact: roads can act as a barrier, whereas other types of infrastructure have minimal effect on movement and home range. We discuss these differences in impact in terms of structure, maintenance schedules, and edge effects of infrastructure.
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Purcea Lopes, Pompilia Mioara, Dumitrita Moldovan, Radu Fechete, Liviu Mare, Lucian Barbu-Tudoran, Niculina Sechel et Violeta Popescu. « Characterization of a Graphene Oxide-Reinforced Whey Hydrogel as an Eco-Friendly Absorbent for Food Packaging ». Gels 9, no 4 (3 avril 2023) : 298. http://dx.doi.org/10.3390/gels9040298.

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This study presents a structural analysis of a whey and gelatin-based hydrogel reinforced with graphene oxide (GO) by ultraviolet and visible (UV-VIS) spectroscopy, Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD). The results revealed barrier properties in the UV range for the reference sample (containing no graphene oxide) and the samples with minimal GO content of 0.66×10−3% and 3.33×10−3%, respectively, in the UV-VIS and near-IR range; for the samples with higher GO content, this was 6.67×10−3% and 33.33×10−3% as an effect of the introduction of GO into the hydrogel composite. The changes in the position of diffraction angles 2θ from the X-ray diffraction patterns of GO-reinforced hydrogels indicated a decrease in the distances between the turns of the protein helix structure due to the GO cross-linking effect. Transmission electron spectroscopy (TEM) was used for GO, whilst scanning electron microscopy (SEM) was used for the composite characterization. A novel technique for investigating the swelling rate was presented by performing electrical conductivity measurements, the results of which led to the identification of a potential hydrogel with sensor properties.
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Culajara, Carla Jobelle. « Barriers to learning and performing in physical education in modular remote learning and coping strategies perceived by the students ». Edu Sportivo : Indonesian Journal of Physical Education 3, no 1 (22 mars 2022) : 11–24. http://dx.doi.org/10.25299/es:ijope.2022.vol3(1).8559.

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Every child deserves access to quality education amidst the COVID 19 pandemic. Students face the test of answering modules much more than doing the performances in the physical education classes. One of the challenges they faced was performing different performance tasks and being able to meet the objectives as well as the learning competencies. This study aimed to determine the barriers in learning performances and students’ coping strategies in physical education in modular distance learning which was accompanied by a quantitative approach using a descriptive – survey method of research. The study was conducted in one of the secondary public schools composed of 201 selected junior high school students. Based on the result of the study, the findings were as follows: majority of the of the respondents were female, grade 9 students and 15 years of age. The barriers exprienced by the students were overthinking about their grades, minimal engagement in performance tasks due to lack of equipments and learning materials, discomfort in doing the task because of distraction at home and unstable internet connection which means it is important to assess and evaluate the learning materials provided in the module to provide accessibility to students capabilities and available materials at home. With regards to students’ coping strategies, it emphasize in developing skills and abilities even in the confinement of home because learning must continue and students have the grit to do their tasks in their modules which indicates the student's opportunities and resiliency was very important factors for the students’ learning and doing performances. To satisfy the students' needs, school leaders must incorporate real methods into their teaching and address their diversity, as well as provide a variety of instructions and learning resources, lesson exemplars, and assistance for the students. To stimulate creativity and assure excellence in educational offerings, colleagues should be given technical assistance and coaching. Professional development should be prioritized during the pandemic to improve intrinsic competencies to plan, manage, and internalize more effective service delivery.
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LaCava, Melanie E. F., Roderick B. Gagne, Sierra M. Love Stowell, Kyle D. Gustafson, C. Alex Buerkle, Lee Knox et Holly B. Ernest. « Pronghorn population genomics show connectivity in the core of their range ». Journal of Mammalogy 101, no 4 (29 mai 2020) : 1061–71. http://dx.doi.org/10.1093/jmammal/gyaa054.

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Abstract Preserving connectivity in the core of a species’ range is crucial for long-term persistence. However, a combination of ecological characteristics, social behavior, and landscape features can reduce connectivity among wildlife populations and lead to genetic structure. Pronghorn (Antilocapra americana), for example, exhibit fluctuating herd dynamics and variable seasonal migration strategies, but GPS tracking studies show that landscape features such as highways impede their movements, leading to conflicting hypotheses about expected levels of genetic structure. Given that pronghorn populations declined significantly in the early 1900s, have only partially recovered, and are experiencing modern threats from landscape modification, conserving connectivity among populations is important for their long-term persistence in North America. To assess the genetic structure and diversity of pronghorn in the core of their range, we genotyped 4,949 genome-wide single-nucleotide polymorphisms and 11 microsatellites from 398 individuals throughout the state of Wyoming. We found no evidence of genetic subdivision and minimal evidence of isolation by distance despite a range that spans hundreds of kilometers, multiple mountain ranges, and three interstate highways. In addition, a rare variant analysis using putatively recent mutations found no genetic division between pronghorn on either side of a major highway corridor. Although we found no evidence that barriers to daily and seasonal movements of pronghorn impede gene flow, we suggest periodic monitoring of genetic structure and diversity as a part of management strategies to identify changes in connectivity.
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Ballesteros, Cristina, Mylène Pouliot, Rémi Froment, Mohamed Said Maghezzi, Camille St-Jean, Christian Li, Dominique Paquette et Simon Authier. « Cerebrospinal Fluid Characterization in Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs ». International Journal of Toxicology 39, no 2 (18 février 2020) : 124–30. http://dx.doi.org/10.1177/1091581820905092.

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Intrathecal administration is an important route for drug delivery, and in pharmacology and toxicology studies, cerebrospinal fluid (CSF) collection and analysis is required for evaluating blood–brain barrier penetration and central nervous system exposure. The characteristics of CSF in commonly used nonrodent models are lacking. The purpose of this study is to evaluate and provide some insights into normal cellular and biochemical composition of CSF as well as diffusion potential following intrathecal injection across several nonrodent species. Cerebrospinal fluid samples were collected from the cerebellomedullary cistern of beagle dogs, cynomolgus monkeys, and Göttingen minipigs and analyzed for clinical chemistry and cytological evaluation. Diffusion into the intrathecal space following intrathecal injection was assessed following administration of a contrast agent using fluoroscopy. The predominant cell types identified in CSF samples were lymphocytes and monocytoid cells; however, lymphocytes were represented in a higher percentage in dogs and monkeys as opposed to monocytoid cells in minipigs. Clinical chemistry parameters in CSF revealed higher Cl− concentrations than plasma, but lower K+, Ca2+, phosphorus, glucose, creatinine, and total protein levels consistent across all 3 species. Diffusion rates following intrathecal injection of iodixanol showed some variability with dogs, showing the greatest diffusion distance; however, the longest diffusion time through the intervertebral space, followed by monkeys and minipigs. Minimal diffusion was observed in minipigs, which could have been attributed to anatomical spinal constraints that have been previously identified in this species.
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Edwards, Devin T., Marc-Andre LeBlanc et Thomas T. Perkins. « Modulation of a protein-folding landscape revealed by AFM-based force spectroscopy notwithstanding instrumental limitations ». Proceedings of the National Academy of Sciences 118, no 12 (15 mars 2021) : e2015728118. http://dx.doi.org/10.1073/pnas.2015728118.

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Single-molecule force spectroscopy is a powerful tool for studying protein folding. Over the last decade, a key question has emerged: how are changes in intrinsic biomolecular dynamics altered by attachment to μm-scale force probes via flexible linkers? Here, we studied the folding/unfolding of α3D using atomic force microscopy (AFM)–based force spectroscopy. α3D offers an unusual opportunity as a prior single-molecule fluorescence resonance energy transfer (smFRET) study showed α3D’s configurational diffusion constant within the context of Kramers theory varies with pH. The resulting pH dependence provides a test for AFM-based force spectroscopy’s ability to track intrinsic changes in protein folding dynamics. Experimentally, however, α3D is challenging. It unfolds at low force (<15 pN) and exhibits fast-folding kinetics. We therefore used focused ion beam–modified cantilevers that combine exceptional force precision, stability, and temporal resolution to detect state occupancies as brief as 1 ms. Notably, equilibrium and nonequilibrium force spectroscopy data recapitulated the pH dependence measured using smFRET, despite differences in destabilization mechanism. We reconstructed a one-dimensional free-energy landscape from dynamic data via an inverse Weierstrass transform. At both neutral and low pH, the resulting constant-force landscapes showed minimal differences (∼0.2 to 0.5 kBT) in transition state height. These landscapes were essentially equal to the predicted entropic barrier and symmetric. In contrast, force-dependent rates showed that the distance to the unfolding transition state increased as pH decreased and thereby contributed to the accelerated kinetics at low pH. More broadly, this precise characterization of a fast-folding, mechanically labile protein enables future AFM-based studies of subtle transitions in mechanoresponsive proteins.
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Mohd Dzulkhairi Mohd Rani, Muslimah Ithnin, Nadeeya ‘Ayn Umaisara Mohamad Nor, Norsham Juliana, Nadia Mohd Effendy, Sahar Azmani, Khadijah Hasanah Abang Abdullah, Muhammad Shamsir Mohd Aris et Izuddin Fahmy Abu. « Comparison of health-seeking behaviour between urban and rural malay population of negeri sembilan, malaysia ». International Journal of Research in Pharmaceutical Sciences 10, no 4 (14 novembre 2019) : 3608–15. http://dx.doi.org/10.26452/ijrps.v10i4.1742.

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There is a growing interest on researches related to health-seeking behaviours. However, there are minimal studies in Malaysia which focus on this issue. This paper aimed to determine the health-seeking behaviours among the Malay population and its association based on the localities of the urban and rural population. To achieve this purpose, a cross-sectional survey was conducted using face-to-face interview method. A total of 480 respondents participated in this survey with the majority (57.7%) of them were from a rural area. Among all the subjects, 4.9% and 5.4% of urban and rural participants respectively, did not seek treatment when they were sick. The reasons being are they chose to ignore the pain (80%), time-consumption (8%), and they do not believe in modern treatments (8%). A higher number of rural participants chose public healthcare facilities compared to urban (82.3% vs 72.6%, p<0.001), whereas a higher number of urban participants chose private healthcare facilities in contrast to rural participants (25.3% vs 16.4%, p<0.001). For participants with chronic diseases, 5.3% did not go for follow-up, 91.2% rely on healthcare staffs for information on the diseases, and 18.9% took traditional or supplementary medicine. Majority of the participants are in agreement that the accessibility to public healthcare facilities in terms of distance, transportation and operational time, as well as the services to get treatments, were good. Overall, majority of the respondents prefer to seek treatments from public healthcare facilities followed by private facilities and pharmacies. However, there is a small number of participants who did not seek for treatments, including those with chronic diseases. Further studies shall be conducted to explore the barriers to seeking treatments in this population.
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Okojie, Paul West, et Richard Lane. « Healthcare Options and Factors Influencing Health Seeking Behavior in a Rural Community in Nigeria ». Christian Journal for Global Health 7, no 2 (30 juin 2020) : 83–92. http://dx.doi.org/10.15566/cjgh.v7i2.335.

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Introduction: Healthcare resources are disproportionately distributed between urban and rural areas in many developing countries including Nigeria. Barriers to healthcare like cultural beliefs, poor education, and financial constraints make many rural dwellers seek other options of healthcare available to them. This paper aimed to determine healthcare options and sociodemographic factors associated with health-seeking practices in a rural community setting. Methods: A sample of 380 rural community dwellers in southern Nigeria was recruited in a cross-sectional study. An interviewer-administered questionnaire was used to collect socio-demographic, healthcare access and utilization data. Data were analyzed with SPSS version 25.0 software. A chi-square test was used to find the association between sociodemographic characteristics and their health-seeking practices. Results: Equal proportions (43.4%, 42.9%) of the respondents fell within the younger age categories of 10-29 and 30-49 years. Self-reported factors influencing the choice of health care were: Promptness of care (41.8%), cost (22.4%), professionalism (16.8%), distance (15.8%), and cultural belief (3.2%). The patent medicine store was the most utilized source of health care (42.1%). 140 (36.8%) respondents sought health care in the hospital. The hospital was utilized by 41.8% of respondents with secondary education; 34.9% with tertiary education; 31.7% primary and 26.1% with no formal education, respectively. Females tended to seek health care from hospitals (40.2%) and patent medicine store (43.7%) compared to males (33.3% and 41.0%). There was a statistically significant association between education and health care options utilized (P<0.05). Conclusion: Less than half of rural dwellers make minimal use of standard health care mainly due to cost and perception of promptness. The health authority should, therefore, prioritize community health education and expand healthcare access to enable rural dwellers to optimize the minimum standard healthcare available within their various communities.
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Hong, Yang-Ki, Kang-Rae Kim, Keun-Sik Kim et In-Chul Bang. « The Impact of Weir Construction in Korea’s Nakdong River on the Population Genetic Variability of the Endangered Fish Species, Rapid Small Gudgeon (Microphysogobio rapidus) ». Genes 14, no 8 (11 août 2023) : 1611. http://dx.doi.org/10.3390/genes14081611.

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Microphysogobio rapidus, an endemic cyprinid fish species found exclusively in Korea, has been identified in only two tributaries of the Nakdong River. The species predominantly occupies the near-gravel bottom waters within shallow sections of the middle and lower reaches of the river, characterized by swift currents. M. rapidus is currently recognized as a critically endangered species due to its distinct habitat preference, as well as the negative impacts of stream dam development and water environment pollution. In this study, we used 10 microsatellite markers to examine the genetic diversity of M. rapidus in the upper Nam (UN), lower Nam (LN), and Deokcheon Rivers (DC) in Korea, with a specific focus on assessment of the impact of dam development. Fish sampled from the UN and LN showed a greater average number of alleles and allelic richness (A = 18.3–18.4, AR = 13.8) compared to those from DC (A = 11.8, AR = 11.5). The observed heterozygosity among the fish examined ranged from HO = 0.748 (LN) to 0.766 (DC). All three fish groups exhibited a significant departure from Hardy–Weinberg equilibrium (HWE) (p < 0.05). Despite having the largest effective population size (Ne = 175 and 157, respectively), the fish sampled from UN and LN showed the highest inbreeding coefficients (FIS = 0.056–0.053, respectively), which were highly significant (p < 0.01). In contrast, the fish sampled from DC exhibited the smallest effective population size (Ne = 61) and showed an inbreeding coefficient close to zero (p > 0.05). BOTTLENECK analysis and estimated M-ratio values (0.341–0.372) revealed indications of past population size reduction in all fish groups examined. No significant genetic differentiation (FST < 0.05) was detected using the DAPC, STRUCTURE, and AMOVA among the fish studied. However, pairwise comparisons of FST between fish sampled from the Nam and Deokcheon Rivers revealed significant values (p < 0.001) ranging from 0.013 to 0.014. In addition, the closest genetic distance (0.026) was observed between UN and LN, while the greatest distance (0.087) was found between UN and DC. Analysis of gene flow rates among the fish examined indicated asymmetrical gene exchange within the Nam River, which was 31.51% in the downstream direction (from UN to LN), with a minimal gene flow rate (0.41%) in the upstream (from LN to UN) direction. The opposite trend was recorded between DC and LN, with a higher gene flow rate (29.74%) in the upstream direction compared to the downstream direction (0.12%). Our study highlighted the importance of implementing long-term conservation efforts focused on maintaining river integrity by removing water barriers such as weirs that impede fish migration and implementing active protection measures, such as aquaculture breeding and reasonable stocking practices, to preserve M. rapidus in the study area.
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Muller, R. U., M. Stead et J. Pach. « The hippocampus as a cognitive graph. » Journal of General Physiology 107, no 6 (1 juin 1996) : 663–94. http://dx.doi.org/10.1085/jgp.107.6.663.

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A theory of cognitive mapping is developed that depends only on accepted properties of hippocampal function, namely, long-term potentiation, the place cell phenomenon, and the associative or recurrent connections made among CA3 pyramidal cells. It is proposed that the distance between the firing fields of connected pairs of CA3 place cells is encoded as synaptic resistance (reciprocal synaptic strength). The encoding occurs because pairs of cells with coincident or overlapping fields will tend to fire together in time, thereby causing a decrease in synaptic resistance via long-term potentiation; in contrast, cells with widely separated fields will tend never to fire together, causing no change or perhaps (via long-term depression) an increase in synaptic resistance. A network whose connection pattern mimics that of CA3 and whose connection weights are proportional to synaptic resistance can be formally treated as a weighted, directed graph. In such a graph, a "node" is assigned to each CA3 cell and two nodes are connected by a "directed edge" if and only if the two corresponding cells are connected by a synapse. Weighted, directed graphs can be searched for an optimal path between any pair of nodes with standard algorithms. Here, we are interested in finding the path along which the sum of the synaptic resistances from one cell to another is minimal. Since each cell is a place cell, such a path also corresponds to a path in two-dimensional space. Our basic finding is that minimizing the sum of the synaptic resistances along a path in neural space yields the shortest (optimal) path in unobstructed two-dimensional space, so long as the connectivity of the network is great enough. In addition to being able to find geodesics in unobstructed space, the same network enables solutions to the "detour" and "shortcut" problems, in which it is necessary to find an optimal path around a newly introduced barrier and to take a shorter path through a hole opened up in a preexisting barrier, respectively. We argue that the ability to solve such problems qualifies the proposed hippocampal object as a cognitive map. Graph theory thus provides a sort of existence proof demonstrating that the hippocampus contains the necessary information to function as a map, in the sense postulated by others (O'Keefe, J., and L. Nadel. 1978. The Hippocampus as a Cognitive Map. Clarendon Press, Oxford, UK). It is also possible that the cognitive mapping functions of the hippocampus are carried out by parallel graph searching algorithms implemented as neural processes. This possibility has the great attraction that the hippocampus could then operate in much the same way to find paths in general problem space; it would only be necessary for pyramidal cells to exhibit a strong nonpositional firing correlate.
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Splodytel, A. O., et I. V. Kuraieva. « ECOLOGICAL AND GEOCHEMICAL EVALUATION OF THE HEAVY METALS CONTENTS IN THE COMPONENTS OF THE LANDSCAPE IN KIVERTSI NATIONAL NATURE PARK “TSUMANSKA PUSHCHA” ». Geological Journal, no 1 (16 avril 2021) : 32–52. http://dx.doi.org/10.30836/igs.1025-6814.2021.1.217344.

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The study presents the results of the spatial distribution of the heavy metal contents in separate components of the landscape of Kivertsi National Nature Park “Tsumanska Pushcha”. The article provides the quantitative indices of the heavy metals contents, which represent the intensity, character, and specificity of the accumulation in the soil horizons. Concentrations of the microelements fluctuate depending on the lithological type of deposits, their facies affiliation, and localization in the drainage basin. The contents of nickel, cobalt, lead, chromium, vanadium, manganese, and copper are characterized by significant divergence from their average concentrations, though it doesn’t exceed their estimated abnormal indices. Most of the studied heavy metals in the soil exceed the regional geochemical background. The biggest accumulation of copper and zinc is taking place in the forest floor, and the mineral part of the profile is lightly marked by alluvial and illuvial character. The contents of nickel, cobalt, and manganese are increasing with the depth with the accumulation of these elements, which are typical of the chemical contents of glacial deposits. The forest floor is distinctly playing the role of a barrier that prevents copper from penetration into the inner levels of occurring soil horizons. The paper defines the dependence of the heavy metal contents in plants of the national nature park on the level of technogenic load and characteristics of the soil covering of the territory. With the increase of the heavy metals in soil, they accumulate in plants. Though, with the distance from the source of contamination, the contents of the heavy metals in plants decrease by 10-20 mg/kg. The study of the most common plants, which grow on the soils of diverse mechanical contents, revealed that the plants which grow on sod-podzolic sandy soil display the biggest number of microelements, while those growing on bog soil and peat bogs. The main part of the exceeding background indices according to the elements has been found in sample areas westwards. All plants under research accumulated Mn, Cu, Cr to a maximal extent while Zn and Ti to a minimal extent, which is in accordance with elements migration of this group. The main directions of further research include the study of heavy metals distribution in diverse genetic types of the soils; definition of the standard contents of the elements in geochemical landscapes needed to identify the intensity of migration and character of elements distribution; performance of biochemical zoning.
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Hayati, Nunung Nuring, et Dano Quinta Revana. « Perancangan Sarana Layanan Akademik Dalam Mengantisipasi Penyebaran Penyakit Menular (Covid-19) Pasca Pandemik ». Jurnal Rekayasa Sipil dan Lingkungan 5, no 2 (31 mai 2022) : 155. http://dx.doi.org/10.19184/jrsl.v5i2.28049.

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The Covid-19 virus, which attacks the respiratory system and is classified as an infectious disease, has been designated a global pandemic. One way to prevent the Covid-19 virus is to implement physical distancing from other people. The impact of this pandemic is affecting the learning system so that the teaching and learning process is carried out online during the pandemic. If later the teaching and learning process is carried out offline, it is necessary to prevent and anticipate the virus so that it does not spread during the teaching and learning process, such as the design of the classroom layout, the design of a virus barrier product design, and the design of a special room design for people with infectious diseases. The layout design in the classroom is made at 50% of the capacity it should have during the previous normal study, to implement physical distancing or keep a distance. Normal human circulation is 2 m2/person, in the new normal period a minimum of 4 m2/person is required. The product design is to limit oneself when the teaching and learning process takes place with the Divider product which is placed on the classroom desk. This divider is made of clear acrylic, sized according to a study table that can be easily carried, easy to store, safe, sturdy, and easy to clean. ABSTRAK Virus Covid-19 yang menyerang sistem pernapasan dan tergolong penyakit menular yang telah ditetapkan menjadi pandemi global. Salah satu pencegahan virus Covid-19 yaitu menerapkan physical distancing dengan orang lain. Dampak dari pandemi ini adalah mempengaruhi pada sistem belajar, sehingga proses belajar mengajar dilakukan secara daring selama pandemi. Jika nantinya proses belajar mengajar dilakukan secara luring, diperlukan pencegahan dan antisipasi virus agar tidak menyebar selama proses belajar mengajar, seperti perancangan tata ruang dalam kelas, perancangan desain produk pembatas virus, dan desain perancangan ruangan khusus untuk penderita penyakit menular. Perancangan tata letak pada ruang kelas dibuat 50% dari kapasitas seharusnya saat belajar normal sebelumnya, guna menerapkan physical distancing atau jaga jarak. Normal sirkulasi manusia adalah 2 m2/orang, pada masa new normal dibutuhkan minimal 4 m2/orang. Perancangan produk guna membatasi diri ketika proses belajar mengajar berlangsung dengan produk Divider yang diletakkan pada meja belajar kelas, Pembatas ini terbuat dari akrilik bening, berukuran sesuai dengan meja belajar yang dapat mudah dibawa, mudah disimpan, aman, kokoh, dan mudah untuk dibersihkan.
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Daassi, Rodrigue, Kalvin Durand, Denis Rodrigue et Tatjana Stevanovic. « Optimization of the Electrospray Process to Produce Lignin Nanoparticles for PLA-Based Food Packaging ». Polymers 15, no 13 (7 juillet 2023) : 2973. http://dx.doi.org/10.3390/polym15132973.

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The development of new processing methods is required in order to meet the continuous demand for thinner films with excellent barrier properties for food packaging and other applications. In this study, rice husk organosolv lignin nanoparticles were prepared using the electrospray method, which were applied to produce polylactic acid (PLA)-based films for food packaging. The effect of the following electrospray parameters has been investigated: lignin concentration (LC) ranging from 5–50 mg/mL, flow rate (FR) from 0.5–1 mL/min, applied voltage from 10–30 kV, and tip-to-collector distance (TCD) from 10–25 cm, on the morphology, size, polydispersity index (PDI), and Zeta potential (ZP) of lignin nanoparticles (LNPs). The response surface methodology with a Box-Behnken design was applied to optimize these parameters, while dynamic light scattering (DLS) and scanning electron microscopy (SEM) analyses were used to characterize the controlled LNPs. The results showed that the LNPs shape and sizes represent a balance between the solvent evaporation, LC, applied voltage, TCD and FR. The application of optimal electrospray conditions resulted in the production of LNPs with a spherical shape and a minimal size of 260 ± 10 nm, a PDI of 0.257 ± 0.02, and a ZP of −35.2 ± 4.1 mV. The optimal conditions were achieved at LC = 49.1 mg/mL and FR = 0.5 mL/h under an applied voltage of 25.4 kV and TCD = 22 cm. Then, the optimized LNPs were used to improve the properties of PLA-based films. Three types of PLA-lignin blend films were casted, namely lignin/PLA, LNPs/PLA and PLA-grafted LNPs. PLA-grafted LNPs exhibited a more uniform dispersion in PLA for lignin contents of up to 10% than other composite samples. Increasing the lignin content from 5% to 10% in PLA-grafted LNPs resulted in a significant increase in elongation at break (up to four times higher than neat PLA). The presence of PLA-grafted lignin led to a substantial reduction in optical transmittance in the UV range, dropping from 58.7 ± 3.0% to 1.10 ± 0.01%, while maintaining excellent transparency to visible light compared to blends containing lignin or LNPs. Although the antioxidant capacity of unmodified lignin is well-known, a substantial increase in antioxidant capacity was observed in LNPs and PLA-grafted LNP films, with values exceeding 10 times and 12 times that of neat PLA, respectively. These results confirm the significant potential of using studied films in food packaging applications.
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Way, M. O., et R. G. Wallace. « Evaluation of Control of the RWW with the Nematode Steinernema Carpocapsae, 1989 ». Insecticide and Acaricide Tests 17, no 1 (1 janvier 1992) : 256. http://dx.doi.org/10.1093/iat/17.1.256.

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Abstract Experiments were conducted in the field and greenhouse at the Texas A&M University Agricultural Research and Extension Center at Beaumont. A basin (120 × 80 ft) with Beaumont clay soil was disced and rototilled in the early spring. On 21 Apr the basin was fertilized with urea at 68 lb nitrogen/acre and drill planted at 100 lb seed/ acre. Distance between rows was 7 inches. The basin was then flooded on the same date and drained 22 Apr. Another flush irrigation was applied 25 Apr and drained the same d. Thiobencarb was applied on 26 Apr at 4 lbs (AI)/acre before rice emergence which occurred 29 Apr. On 23 May propanil at 3 lbs (AI)/acre and bentazon at 0.5 lbs (AI)/acre were applied followed by an application of urea at 51 lbs nitrogen/acre on 26 May. Sixteen plots (each 13 × 6 ft) were arranged in a randomized complete block (4 treatments and 4 replications) within the basin. A metal barrier was placed around each plot to prevent treatment contamination among plots. As soon as the barriers were in place a permanent flood (4 inches deep) was applied to the basin on 26 May. The basin was flush irrigated when needed between rice emergence and the permanent flood. On 7 Jun (12 d after the onset of the permanent flood) Furaden 3 GF was applied, using a hand-held shaker, at 0.6 lbs (AI)/acre to selected plots. On 8 Jun the basin was drained and nematode #25 (Steinernema carpocapsae) was applied 9 Jun to selected plots at 250/inch2 using a 4-nozzle hand held sprayer (R&D Sprayers, Inc. Model AS) equipped with 800067 tips and 100 mesh screens. Finished spray vol was 66 gal/acre. Spray was propelled with CO2 at 22 psi. Application was made at dusk when conditions were calm and the boom was kept below the top of the metal barrier. Thus, drift and exposure to UV radiation were minimal at time of application. The basin was reflooded 12 Jun. Soil remained moist during the drain period. On 3 Jul 5 soil cores (4 inch diam × inches deep); each containing about 1 plant, were removed from each plot. Plants were washed in a 40-mesh screen bucket and RWW larvae and pupae were recovered and counted. In a greenhouse experiment, Beaumont clay soil, obtained from a fallow rice research basin, was sifted through an 8 mesh screen (8 squares/inch). Thirty-six paper cups (4.25 inch diam × 5.25 inch tall) were filled with the sifted soil to 1 inch from the top. The soil in each cup was fertilized with urea at 68 lbs nitrogen/acre. Each cup was planted with 6 seeds and flush irrigated from planting until plants were about 8 inches tall at which time rice was thinned to 1 healthy plant/cup. Weeds were removed by hand. Cups were arranged in a randomized complete block (6 treatments with 6 replications) after placement in a large metal pan which was filled with water to about 1 inch from the top of the cups. Cups were filled with water so that plants were exposed to about a 2 inch flood. On 21 Aug RWW adults were collected from late planted rice at the Texas A&M University Agricultural Research and Extension Center at Beaumont. Cylindrical transparent cages made of polyactetate were placed over selected plants which were in the 3-leaf stage and about 12 inches tall. Three female and 1 male RWW were placed in each cage on 21 Aug. The tops of the cages were covered with polyester netting to prevent escape of the insects. On 24 Aug (3 d after infesting plants) cages were removed and adult RWW were found and destroyed. On 20 Sep designated cups were drained and nematode #25 (Steinernema carpocapsae) was applied to designated flooded and drained cups at the rate of 250/inch2. Thus, nematodes were applied to flood water and moist soil containing plants infested and not infested with the RWW. Treatments were applied by pipette after proper dilution of a stock suspension of nematodes was prepared. Each treated cup received 7.7 ml of the proper dilution of nematode suspension. All drained cups were reflooded 22 Sep. On 27 Sep RWW infested plants from cups treated with nematodes were washed in a screen bucket and RWW larvae and pupae were recovered and counted. The soil from remaining cups (treated with nematodes but not infested with WW) was sent to BIOSYS for nematode bioassay. Data for field and greenhouse experiments were transformed using Vx + 0.5 and analyzed by ANOVA and where appropriate means separated by DMRT.
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Chaulagain, Chakra Pani, Ludovic Saba, Hong Liang, Barbara Dominguez et Chieh Lin Fu. « Determinants of overall survival of young adults with multiple myeloma : A National Cancer Database (NCDB) analysis of years 2004-2017. » Journal of Clinical Oncology 41, no 16_suppl (1 juin 2023) : 8052. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.8052.

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8052 Background: There is paucity of real-world data on the outcomes of younger patients with multiple myeloma (MM). In this IRB approved retrospective analysis, the NCDB was used to evaluate the determinants of overall survival (OS) of young adults ≤ 50 years with MM who were treated at commission on cancer (CoC) accredited facilities across the USA. Methods: Using the NCDB, we identified N = 16,792 patients ≤ 50 years old diagnosed and treated for MM from 2004 to 2017. Multivariable cox regression analysis with backward elimination was utilized to identify the independent survival factors, using significance level of p < 0.05. Kaplan-Meier survival curves were generated and SAS version 9.4 was used to analyze the data. Results: Overall median survival time was 119 months; while survival rates of 1, 3, and 5-year were 90.6%, 78.0%, and 67.8%, respectively. Multivariable cox regression analysis with backward elimination method revealed that there were 13 significant independent survival factors: age, sex, race, ethnicity, Charlson-Deyo score, insurance status, facility type, median income, education level, distance to facility, year of diagnosis, hematopoietic stem-cell transplantation (HSCT), and treatment-regimen. Male patients were more likely to die compared to female patients (HR = 1.22, p < 0.0001). Black patients were predicted to have less death events compared to White patients (HR = 0.91, p = 0.004). In addition to that, Hispanic patients were more likely to die compared to non-Hispanics (HR = 1.2, p = 0.0006). Subjects who were treated in non-academic facilities were more likely to die compared to the ones who received care in academic centers (HR = 1.2, p < 0.0001). Moreover, patients with Medicare (HR = 1.65, p < 0.0001), Medicaid (HR = 1.49, p < 0.0001), and no insurance (HR = 1.63, p < 0.0001) had higher chance of death compared to those with private insurance. Patients with lower income < $38,000 were more likely to die compared to income ≥ $63,000 (HR = 1.19, p = 0.0007). Only 6.8% of patients underwent HSCT and 93.2% did not. Patients undergoing HSCT had worse OS compared to those treated without HSCT (HR = 0.36, p < 0.0001). Detailed analysis will be presented. Conclusions: In this large cohort of real-world data analysis of very young MM patients, we found that White and Hispanic patients age ≤ 50 years had significantly inferior survival compared to Black and non-Hispanic patients. Patients with lower income, lower education level, non-private insurance, and those without access to academic centers for MM care had worse survival outcomes. The findings can be useful for designing prospective studies addressing disparity and equitable access to MM care. Despite being a pivotal part of MM therapy, HSCT utilization in the real-world setting is minimal. The barriers to HSCT utilization and the reason why it is inferior to no-HSCT in real-world setting need to be identified and addressed.
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Rose, Melanie, Renata Yen, Sybil Sha, Aricca Van Citters, Anna Tosteson, Kenneth Meehan et Nirav Kapadia. « Abstract A098 : Preliminary results of a self-reported financial toxicity survey study among rural cancer patients treated with radiotherapy ». Cancer Epidemiology, Biomarkers & ; Prevention 32, no 12_Supplement (1 décembre 2023) : A098. http://dx.doi.org/10.1158/1538-7755.disp23-a098.

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Abstract Purpose/objectives: Direct and indirect expenses associated with cancer treatment can lead to finanical toxicity (FT), which is associated with reduced compliance and worse outcomes. Little is known regarding the FT experienced by cancer patients in rural areas, where added barriers impair timely accural and completion of survey data. To increase our understanding of FT experiencd by a rural population receiving radiation therapy, we piloted a validated survey of financial toxicity and report of the feasibility of recruitment, retention, and data collection. Materials/Methods: Instituitonal approval was obtained to propsectively survey rural Northern New England radiation oncology patients served at the outreach clinic in St. Johnsbury, VT ssociated with a teritiary academic medialc center. Baseline survey was provided at time of simulation with weekly follow-up surveys provided during on-treatment visits and at regular follow-up visits up to 6 months post-completion of therapy. At baseline, respondents reported on demographics (including sex, race, education, language, insurance, employment), weekly income, expenses, travel distance, the validated COmprehensive score for financial toxicity (COST), perspectives regarding providers' understanding and empathy of finances, and summary measure of meaningful sum of weekly money to improve their financial sitution. A modified version of this survey was provided to partcipants at subsequent visits. Results: 26 participants signed consent from 09/2022 to 01/2023 with ongoing weekly survey data collection. At baseline, patients were largely elderly (mean 68 years), mostly male (25 of 26), and white (24 of 26). Most were lower socioeconomic status, as 46% reported yearly income less than $47,000, and 50% were educated at a high-school level or less. Most patients (69%) were insured through Medicare, and three were dually enrolled in Medicaid and Medicare. The mean COST score was 12.43 (SD 11.52, range 0-44). In terms of data completion, 50% of participants (13/26) have completed questionnaires through week six of treatment, resulting in 143 completed weekly surveys. 92.6% of surveys were completed in terms of all data elements. The least responded-to prompt queried the meaninful sum of weekly money; only 81 of 143 surveys (56.6%) indicated a response, which at week 1 was $236.11 (medial; IQR $75 to $500). All other sections contained minimal data missing. Conclusions: FT surveys of rural radiaiton oncology population with a range of educational backgrounds is feasible with high fidelity of data collection. Future steps will focus on completing follow-up of the current cohort, analyzing trends, and increasing number of observed patients to idenitfy patterns and predictors of severe FT. Citation Format: Melanie Rose, Renata Yen, Sybil Sha, Aricca Van Citters, Anna Tosteson, Kenneth Meehan, Nirav Kapadia. Preliminary results of a self-reported financial toxicity survey study among rural cancer patients treated with radiotherapy [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr A098.
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Agustin, Dyan, et Erwin Djuni. « KAJIAN PENATAAN RUANG STUDIO GAMBAR PROGRAM STUDI ARSITEKTUR DI ERA NEW NORMAL PANDEMIC COVID 19 ». NALARs 20, no 1 (13 janvier 2021) : 45. http://dx.doi.org/10.24853/nalars.20.1.45-52.

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ABSTRAK. Pada Program Studi Arsitektur salah satu proses kegiatan yang penting adalah kegiatan perancangan dengan beberapa tahapan antara lain membuat konsep, rancangan gambar dua dimensi dan tiga dimensi dan pembuatan maket. Kegiatan tersebut dilakukan di studio gambar dengan penataan dan bentuk pengelolaan desain ruang kuliah yang khusus. Pada saat sebelum pandemic desain ruang kuliah studio hanya didasarkan pada aktivitas di dalam kegiatan perancangan.Pada saat pandemic covid 19 sekarang ini mengharuskan sebuah desain ruang kuliah studio yang bisa menyesuaikan dengan kebutuhan protokol kesehatan untuk memutus rantai penyebaran virus. Metode yang digunakan adalah deduktif kualitatif dengan menggambarkan kondisi ruang kuliah studio dan penyebaran kuesioner kepada para mahasiswa melalui pengisian kuesioner online. Hasil dari penelitian ini adalah analisis desain penataan perabot ruang kuliah studio berdasarkan protokol kesehatan antara lain pada fasilitas fisik meliputi dimensi, desain wujud konfigurasi, desain pembatas antar kursi. Dimensi baru yang dihasilkan berdasarkan pertimbangan new normal adalah keefektifan sebesar 31,5% dengan jarak antar kursi minimal 1 meter. Sedangkan desain wujud konfigurasi yang paling optimal adalah tipe rectangle. Pada desain pembatas antar kursi dihasilkan desain partisi yang berfungsi menghalangi droplet antar mahasiswa dan dosen di dalam ruangan. Untuk sirkulasi dan sign diberikan tanda pada ruang kuliah studio agar arah masuk dan keluar tidak berpapasan. Dengan dihasilkannya desain ruang kuliah studio yang optimal di program studi arsitektur yang sesuai dengan kondisi pandemic covid 19 maka diharapkan akan tercapai peningkatan mutu pembelajaran juga bisa tetap mendukung program pemutusan mata rantai virus covid 19. Kata kunci:perabot, studio, arsitektur, new normal ABSTRACT. One of the essential activity processes in the Architecture Study Program is a design activity with several stages, including conceptualization, two-dimensional and three-dimensional drawing designs, and making mock-ups. This activity is carried out in a drawing studio with a particular arrangement and management of lecture room designs. Before the pandemic, the design of studio lecture rooms was only based on activities in design activities. At the time of the current Covid 19 pandemic, it requires a studio lecture room design that can adapt to health protocols' needs to break the chain of the spread of the virus. The method used is qualitative deductive by describing the studio lecture room conditions and distributing questionnaires to students through online questionnaire filling. This study analyses the design of studio lecture room furniture based on health protocols, among others, the physical facilities, including dimensions, configuration design, and barrier design between chairs. The new size produced based on the new normal considerations is the effectiveness of 31.5% with a minimum distance of 1 meter between seats.Meanwhile, the most optimal configuration design is the rectangle type. In the divider design between chairs, a partition design is produced, which functions to block droplets between students and lecturers in the room. For circulation and sign is given a warning in the studio lecture room so that the entry and exit direction does not cross. With the production of an optimal studio lecture room design in an architecture study program following the conditions of the Covid 19 pandemic, it is hoped that an increase in the quality of learning will be achieved and can continue to support the program to break the Covid 19 chain link. Keywords: furniture, studio, architecture, new normal
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Tiab, Djebbar, et Anh V. Dinh. « Inferring Interwell Connectivity from Well Bottomhole-Pressure Fluctuations in Waterfloods ». SPE Reservoir Evaluation & ; Engineering 11, no 05 (1 octobre 2008) : 874–81. http://dx.doi.org/10.2118/106881-pa.

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Summary This paper presents a new procedure to determine interwell connectivity in a reservoir on the basis of fluctuations of bottomhole pressure of both injectors and producers in a waterflood. The method uses a constrained multivariate linear-regression (MLR) analysis to obtain information about permeability trends, channels, and barriers. Previous authors applied the same analysis to injection and production rates to infer connectivity between wells. In order to obtain good results, however, they applied various diffusivity filters to the flow-rate data to account for the time lags and the attenuation. This was a tedious process that requires subjective judgment. Shut-in periods in the data, usually unavoidable when a large number of data points were used, created significant errors in the results and were often eliminated from the analysis. This new method yielded better results compared with the results obtained when production data were used. Its advantages include:no diffusivity filters needed for the analysis,minimal number of data points required to obtain good results,and flexible plan to collect data because all constraints can be controlled at the surface. The new procedure was tested by use of a numerical reservoir simulator. Thus, different cases were run on two fields, one with five injectors and four producers and the other with 25 injectors and 16 producers. For a large waterflood system, multiple wells are present and most of them are active at the same time. In this case, pulse tests or interference tests between two wells are difficult to conduct because the signal can be distorted by other active wells in the reservoir. In the proposed method, interwell connectivity can be obtained quantitatively from multiwell pressure fluctuations without running interference tests. Introduction Well testing is a common and important tool of reservoir characterization. Many well-testing methods have been developed in order to obtain various reservoir properties. Interference tests and pulse tests are used to quantify communication between wells. These methods are often applied to two wells such that one well sending the signals (by changing flow rates) and the other is receiving them (Lee et al. 2003). For a large field such as a waterflood system, however, multiple wells are present, and most of them are active at the same time. In that case, pulse tests or interference tests between two wells are difficult to conduct because the signal can be distorted by other active wells in the reservoir. In this method, data can be obtained from multiwell pressure tests that resemble interference tests. Thus, we can have several wells sending signals and the others receiving the signals at the same time. The wells that are receiving the signal, however, can either be shut in or kept at constant producing rates. The pressures at all wells are recorded simultaneously within a constant time interval. The length of the test will depend on the length of the time interval and the number of data points. Results of this method can be used to optimize operations and economics and enhance oil recovery of existing waterfloods by changing well patterns, changing injection rates, recompletion of wells, and infill drilling. This work is based on previous work conducted by Albertoni and Lake (2003) by use of injection and production rates. In their work, Albertoni and Lake developed and tested different approaches by use of constrained MLR analysis with a numerical simulator and then applied it to a waterflooded field in Argentina. They used diffusivity filters to account for the time lag and attenuation of the data. In his thesis, Dinh (2003) verified the method by use of a different reservoir simulator and applied it to a waterflooded field in Nowata, Oklahoma. He also investigated the effect of shut-in periods and vertical distances on the results. The main objectives of this work are to verify the results obtained from pressure data with results from flow-rate data to propose a new method to determine interwell connectivity and to suggest further research and study on the method. Similar to the method that uses production rates, we will concentrate on a waterflood system only. The reservoir is considered as a system that processes a stimulus (i.e., a well that is sending signals) and returns a response (i.e., a well that is receiving the signals). The effect of the reservoir on the input signal will depend on the location and the orientation of each stimulus/response pair. Because the total pressure changes at active and observation wells are not equal, only the MLR (Albertoni and Lake 2003; Dinh 2003; Albertoni 2002) was used. The effect of diffusion was not significant, thus the diffusivity filters were not used. The method was applied to two synthetic fields, one with five injectors and four producers and the other with 25 injectors and 16 producers.
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Huynh, C., E. Clement, D. DeGirolamo, A. Kleiman, R. Ralph-Edwards, L. Streith, J. Bogach et al. « Canadian Surgery Forum 201901. The future of general surgery training : a Canadian resident nationwide Delphi consensus statement02. Traumatized : Can mindfulness lead to improved mental health outcomes after multisystem trauma?03. Operating room availability for general surgery in 2007 versus 2017 at a regional hospital in BC04. Perceptions and barriers to Gastrografin protocol implementation05. Resident opinions and educational experience of a mixed night-float system for general surgery resident call06. A scoping review of best management for hepato-pancreatobiliary trauma07. Simultaneous versus staged resection for synchronous colorectal liver metastases : a population-based cohort study08. Weight loss following hepatopancreatobiliary surgery. How much is too much?09. Uptake and patient outcomes of laparoscopic liver resection for colon cancer liver metastases : a population-based analysis10. Simultaneous resection of colorectal cancer with synchronous liver metastases : a survey-based analysis11. When is it safe to start VTE prophylaxis after blunt solid organ injury ? A prospective study from a level I trauma centre12. Undertriaged trauma patients : Who are we missing?13. Trauma team activation at a level I trauma centre : time of day matters14. The diagnostic dilemma of shotgun injuries15. Evaluating the efficacy of self-study videos for the surgery clerkship rotation : an innovative project in undergraduate surgical education16. Systematic review and meta-analysis : preoperative anti-TNF therapy does not increase the risk of postoperative complications in patients with inflammatory bowel disease undergoing elective surgery17. Simulation platforms to assess laparoscopic suturing skills : a scoping review18. Cost analysis of simultaneous versus staged resection of colorectal cancer liver metastases : a population-based study19. Complementary and alternative medicine use among general surgery patients in Nova Scotia20. General surgery in Canada : current scope of practice and future needs21. Impact of dedicated operating time on access to surgical care in an acute care surgery model22. Adolescent appendicitis management and outcomes : comparison study between adult and pediatric institutions23. A systematic review of behavioural interventions to improve opioid prescribing after surgery24. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in trauma : a gap analysis of the Edmonton Zone Trauma Registry25. Learning by holographic anatomic models for surgical education26. The nature of learning from trauma team simulation27. Comparing reversing half-hitch alternating postsurgical knots and square knots for closure of enterotomy in a simulated deep body cavity : a randomized controlled trial28. Propagating the “SEAD” : exploring the value of an overnight call shift in the Surgical Exploration and Discovery Program29. Comparing 2 approaches to residency application file review30. A Canadian experience with posterior retroperitoneoscopic adrenalectomy31. A cost-efficient, realistic breast phantom for oncoplastic breast surgery training32. Impact of patient frailty on morbidity and mortality after common emergency general surgery operations33. Preventing opioid prescription after major surgery : a scoping review of the literature on opioid-free analgesia34. Correct usage of propensity score methodology in contemporary high-impact surgical literature35. Responsible blood compatibility testing for appendectomy : practice assessment at a single Canadian academic centre36. What patient factors are associated with participation in a provincial colorectal cancer screening program?37. Missed appendix tumours owing to nonoperative management for appendicitis38. Operative delay increases morbidity and mortality in emergency general surgery patients : a study of multiple EGS services within a single city39. Withdrawn40. Improved disease-free survival after prehabilitation for colorectal cancer surgery41. Development of a conceptual framework of recovery after abdominal surgery42. Comparison of Dor and Nissen fundoplication following laparoscopic paraesophageal hernia repair43. A systematic review and summary of clinical practice guidelines on the periprocedural management of patients on antithrombotic medications undergoing gastroenterological endoscopy44. Impact of socioeconomic status on postoperative complications following Whipple procedure for pancreatic ductal adenocarcinoma45. Clinical outcomes of high-risk breast lesions and breast cancer patients treated with total mastectomy and immediate reconstruction46. My On Call (MOC) Pager App : practising and assessing safe clinical decision-making47. Comprehensive complication index for major abdominal surgeries : an external validation using the American College of Surgeons’ National Surgical Quality Improvement Program (ACS NSQIP)48. The impact of surgeon experience on script concordance test scoring49. Decay of competence with extended research absences during postgraduate residency training : a scoping review50. Long-term outcomes of elderly patients managed nonoperatively for choledocholithiasis51. Predictors of mortality and cost among surgical patients admitted to hospital and requiring rapid response team activation52. Sex-based disparities in the hourly earnings of surgeons in Ontario’s fee-for-service system53. Outcomes of intestinal ischemia among patients undergoing cardiac surgery54. Factors influencing resident teaching evaluations : the relationship between resident interest in teaching, career plan, training level and their performance in teaching junior learners55. Validating a uniform system for measuring disease severity in acute colonic diverticulitis56. Active negative pressure peritoneal therapy and C-reactive protein (CRP) levels after abbreviated laparotomy for abdominal trauma or intraabdominal sepsis : the validity of serum and peritoneal CRP in measuring outcomes in critically ill patients57. Intraoperative use of indocyanine green fluorescence in emergency general surgery : a systematic review58. Is it safe ? Nonoperaive management of blunt splenic injuries in geriatric trauma patients59. Bladder injury from laparoscopic appendicectomy : a multicentre experience over 5 years60. Perioperative cardiac investigations for chest pain after parathyroidectomy rarely yield a cardiac diagnosis61. Entero-hepatic axis injury following hemorrhagic shock : a role for uric acid62. Loss of functional independence after emergency abdominal surgery in older patients : a prospective cohort study63. Association between use of nonsteroidal antiinflammatory drugs, diuretics or angiotensin converting enzyme inhibitor/receptor blockers after major surgery and acute kidney injury : a nested, population-based case–control study64. Timing of CT for adhesive small bowel obstructions (SBO)65. The ABDO (Acute Biliary Disease Optimization) Study : improving the management of biliary diseases in emergency general surgery66. Rates and predictors of advanced biliary imaging and interventions in acute care surgery : a quality improvement study67. The use of early warning scores in patients undergoing emergency general surgery : a systematic review68. Does primary closure versus resection and anastomosis in patients with hollow viscus injury affect 30-day mortality?69. Impact of sarcopenia on morbidity and mortality after Whipple procedure for pancreatic ductal adenocarcinoma70. Mind the speaker gap : a cross-specialty analysis of the representation of women at surgical meetings in 5 different geographic regions71. Immediate breast reconstruction in locally advanced breast cancer : Is it safe?72. An administrative review of the incidence of adverse events involving electrocautery73. If you don’t document it, did it really happen ? A review of the documentation of informed consent in laparoscopic cholecystectomy74. Can an online module help medical students gain confidence and proficiency in writing orders?75. The influence of undergraduate medical education anatomy exposure on choice of surgical specialty : a national survey76. Association between patient engagement and surgical outcomes : a pilot study77. Guidelines on the intraoperative transfusion of red blood cells : a systematic review78. Cancer is common in missed appendicitis : a retrospective cohort study79. Everyone is awesome : analyzing letters of reference in a general surgery residency selection process80. Evaluating the true additional costs of general surgery complications using a propensity score weighted model81. Deriving literature-based benchmarks for surgical complications from national databases in high-income countries : a systematic review on pancreatectomy outcomes82. The impact of distance on postoperative follow-up in pediatric general surgery patients : a retrospective review83. Water-soluble contrast in adhesive small bowel obstruction management : a Canadian centre’s experience84. Recognizing predatory journals in general surgery and their common violations85. Prophylactic negative pressure wound therapy for closed laparotomy incisions : a meta-analysis of randomized controlled trials86. Choosing Wisely Canada : 2019 general surgery recommendations87. Content-specific resident teaching can improve medical student learning outcomes on certifying examinations88. Transition to practice : preparedness for independent practice in general surgery graduates89. CAGS Exam 2.0 : maximizing the potential for teaching and learning90. Resident attitudes toward the introduction of synoptic operative reporting for appendectomy and cholecystectomy91. Determining the individual, hospital and environmental cost of unnecessary laboratory investigations for patients admitted to general surgery services at an academic centre92. Gender-based compensation disparity among general surgeons in British Columbia93. Transgastric robotic resection for gastrointestinal stromal tumours of the stomach94. Recurrent gallstone ileus after laparoscopic-assisted enterolithotomy treated with totally laparoscopic enterolithotomy01. Predictors and outcomes among patients requiring salvage APR for the treatment of squamous cell carcinoma of the anus : a population-based study02. Short-course radiotherapy with perioperative systemic chemotherapy for patients with rectal cancer and synchronous resectable liver metastases : a single-centre Canadian experience03. Compliance with preoperative elements of the American Society of Colon and Rectal Surgeons rectal cancer surgery checklist improves pathologic and postoperative outcomes04. Clinical predictors of pathologic complete response following neoadjuvant chemoradiation therapy for rectal cancer : a systematic review and meta-analysis05. Rejected06. The impact of laparoscopic technique on the rate of perineal hernia after abdominoperineal resection of the rectum07. An assessment of the current perioperative practice, barriers and predictors for utilization of enhanced recovery after surgery protocols : a provincial survey08. Regional variation in the utilization of laparoscopy for the treatment of rectal cancer : the importance of fellowship training sites09. Local versus radical surgery for early rectal cancer with or without neoadjuvant or adjuvant therapy : a systematic review and meta-analysis10. The relation between the gut microbiota and anastomotic leak in patients with colorectal cancer : a preliminary feasibility study11. Optimizing discharge decision-making in colorectal surgery : an audit of discharge practices in a newly implemented enhanced recovery pathway12. Trends in colectomy for colorectal neoplasms in ulcerative colitis (UC) patients over 2 decades : a National Inpatient Sample database analysis13. Spin in minimally invasive transanal total mesorectal excision articles (TaTME) : an assessment of the current literature14. Venous thromboembolism (VTE) in colon cancer : a population-based cohort study of VTE rates following surgery and during adjuvant chemotherapy15. Robotic-assisted lateral lymph node dissection for rectal neuroendocrine tumor16. Loop ileostomy and colonic lavage as an alternative to colectomy for fulminant Clostridium difficile colitis17. Recurrent diverticulitis : Is it all in the family?18. Le traitement des fistules entérocutanées complexes : expérience du Centre hospitalier de l’Université de Montréal (CHUM)19. A North American single-blinded pilot randomized controlled trial for outpatient nonantibiotic management of acute uncomplicated diverticulitis (MUD TRIAL) : feasibility and lessons learned20. Treatment failure after conservative management of acute diverticulitis : a nationwide readmission database analysis21. Impact of immunosuppression on mortality and major morbidity following sigmoid colectomy for diverticulitis : a propensity-score weighted analysis of the National Inpatient Sample22. Presentation and survival in colorectal cancer under 50 years of age : a systematic review and meta-analysis23. Genetics of postoperative recurrence of Crohn’s disease : a systematic review and meta-analysis24. Improving the identification and treatment of preoperative anemia in patients undergoing elective bowel resection25. Impact of postoperative complications on quality of life after colorectal surgery26. Colon cancer survival by subsite : a retrospective analysis of the National Cancer Database27. A second opinion for T1 colorectal cancer pathology reports results in frequent changes to clinical management28. Effects of the quadratus lumborum block regional anesthesia on postoperative pain after colorectal resection : a double-blind randomized clinical trial29. Safety of a short-stay postoperative unit for the early discharge of patients undergoing a laparosocpic right hemicolectomy30. What is the optimal bowel preparation to reduce surgical site infection in Crohn disease?31. TaTME surgery and the learning curve : our early experience32. Watch-and-wait experience in patients with rectal cancer : results in selected patients at a high-volume centre01. Automatic referral of suspicious findings detected on thoracic CT scan decreases delays in care without compromising referral quality02. Variation in receipt of therapy and survival with provider volume in noncurative esophagogastric cancer : a population-based analysis03. What makes patients high risk for lobectomy in the era of minimally invasive lobectomy?04. The value proposition of minimally invasive esophagectomy : a community hospital perspective05. Deviation from treatment plan in patients with potentially curable esophageal carcinoma06. Implementation of a standardized minimal opioid prescription for post-thoracic surgery patients is feasible and provides adequate pain control07. Sentinel node navigation surgery using indocyanine green in lung cancer : a systematic review and meta-analysis08. Surgical outcomes with trimodality neoadjuvant versus adjuvant therapy for esophageal cancer : results of the QUINTETT randomized trial09. Enhanced invasive mediastinal staging in an academic thoracic surgical unit by employing a shared accountability model for quality improvement10. Evaluation and harmonization of international database elements for adverse events monitoring following thoracic surgery : the pursuit of a common language11. Endobronchial ultrasound staging of operable non–small cell lung carcinoma : triple-negative lymph nodes may not require routine biopsy12. Wait times in the management of non-small cell lung cancer before, during and after regionalization of lung cancer care : a high-resolution analysis13. Wearable technology for preconditioning before thoracic surgery : a feasibility study14. Impact of carbohydrate-loading enhanced recovery after surgery protocol on adverse cardiopulmonary events in a thoracic surgery population15. Heat production during pulmonary artery sealing with energy vessel-sealing devices in a porcine model16. Who can afford to wait ? The effect of wait times on survival in lung cancer patients : clinical predictors of poor outcomes17. Impact of the Integrated Comprehensive Care Program after thoracic surgery : a propensity score matched study18. Incidence, severity and risk of postoperative pulmonary complications in patients undergoing pulmonary resection for cancer19. Evaluation of the limits of use of a thoracoscopic lung palpation device to identify artificial tumour nodules in ex-vivo tissue20. Personalized surgical management of esophagogastric junction cancers21. Validity of a model to predict the risk of atrial fibrillation after thoracic surgery22. Severe symptoms persist for up to 1 year after diagnosis of stage I–III lung cancer : an analysis of province-wide patient-reported outcomes23. Do postoperative infectious adverse events influence cancer recurrence and survival after surgical resection of esophagogastric cancers ? Experience from a Canadian university centre24. Utilization, safety and efficacy of hybrid esophagectomy on a population level25. Endoscopic submucosal dissection for upper gastrointestinal neoplasia : lessons learned from a high-volume North American centre26. Long-term quality of life after esophagectomy27. Early and late outcomes after surgery for pT4 NSCLC reclassified by AJCC 8th edition criteria28. Early results on the learning curve for subxiphoid video-assisted thoracoscopic lobectomy29. Should adjuvant therapy be offered for patients undergoing esophagectomy after neoadjuvant CROSS protocol for esophageal cancer ? A multicentre cohort study30. Outcomes of patients discharged home with a chest tube following anatomic lung resection : a multicentre cohort study01. Management of cancer-associated intestinal obstruction in the final year of life02. Evaluating the prognostic significance of lymphovascular invasion in stage II and III colon cancer03. A matched case–control study on real-time electromagnetic navigation for breast-conserving surgery using NaviKnife04. Gaps in the management of depression symptom screening following cancer diagnosis : a population-based analysis of prospective symptom screening05. Patterns of symptom burden in neuroendocrine tumours : a population-based analysis of patient-reported outcomes06. Outcomes of salvage surgery for anal canal squamous cell carcinoma : a systematic review and meta-analysis07. Expression of the Plk4 inhibitor FAM46C predicts better survival following resection of gastric adenocarcinoma08. Current treatment strategies and patterns of recurrence in locally advanced colon cancer09. A 5-year retrospective review of outcomes after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in a provincial peritoneal malignancy program10. Withdrawn11. Geographic disparities in care and outcomes for noncurative pancreatic adenocarcinoma : a population-based study12. How often is implant-based breast reconstruction following postmastectomy radiation unsuccessful?13. Comparison of partial mastectomy specimen volume and tumour volume following neoadjuvant chemotherapy in breast cancer14. Two-year experience with hookwire localized clipped node and sentinel node as alternative to targeted axillary dissection in a regional centre15. Opioid use among cancer patients undergoing surgery and their associated risk of readmissions and emergency department visits in the 1-year postsurgical period16. Preliminary results of a pilot randomized controlled trial comparing axillary reverse mapping with standard axillary surgery in women with operable breast cancer17. Complementary and alternative medicine among general surgery patients in Nova Scotia18. Improving wait times and patient experience through implementation of a provincial expedited diagnostic pathway for BI-RADS 5 breast lesions19. Population-based regional recurrence patterns in Merkel cell carcinoma : a 15-year review20. Survival and health care cost benefits of high-volume care in the noncurative management of pancreatic adenocarcinoma : a population-based analysis21. Trends in the use of sentinel node biopsy after neoadjuvant chemotherapy in the United States22. Predictors of grossly incomplete resection in primary retroperitoneal sarcoma (RPS)23. Mastectomy versus breast conservation therapy : an examination of how individual, clinicopathologic and physician factors influence decision making24. Immunophenotyping postoperative myeloid-derived suppressor cells in cancer surgery patients25. Adherence to sentinel lymph node biopsy guidelines in the management of cutaneous melanoma in the province of British Columbia26. Breast cancer with supraclavicular and internal mammary node metastases : therapeutic options27. Textbook outcomes and survival in patients with gastric cancer : an analysis of the population registry of esophageal and stomach tumours of Ontario (PRESTO)28. Withdrawn29. Symptomatic bowel complications in patients with metastatic cancer : comparison of surgical versus medical outcomes and development of a prediction model for successful surgical palliation30. Rejected31. Gastric cancer biopsies show distinct biomarker profiles compared with normal gastric mucosa in Canadian patients32. Withdrawn01. Management of high patient-reported pain scores in noncurative pancreatic adenocarcinoma : a population-based analysis02. Outcomes of liver donors with a future liver remnant less than or equal to 30% : a matched-cohort study03. The applicability of intraoperative fluorescent imaging with indocyanine green in hepatic resection for malignancy : a systematic review and meta-analysis04. Impact of adjuvant chemotherapy completion on outcomes following pancreaticoduodenectomy for pancreatic ductal adenocarcinoma05. Primary hepatic acinar cell carcinoma06. Laparoscopic distal pancreatectomy provides equivalent oncologic outcomes for pancreatic ductal adenocarcinoma07. Passive versus active intraabdominal drainage following pancreatic resection : Does a superior drainage system exist ? A systematic review and meta-analysis08. Low yield of preoperative MRCP and ERCP in the management of low-intermediate suspicion choledocholithiasis09. Pancreatic cancer resection rates and survival in the United States and Canada10. Prognostic value of immune heterogeneity in colorectal cancer liver metastases11. Impact of intraoperative hypovolemic phlebotomy on blood loss and perioperative transfusion in patients undergoing hepatectomy for cancer12. Prediction of postoperative pancreatic fistula following pancreatectomy : a systematic review of clinical tools13. The impact of preoperative frailty in liver resection : an analysis of the American College of Surgeons’ National Surgical Quality Improvement Program (ACS NSQIP)14. Topical agents as adjuncts in pancreatic surgery for prevention of postoperative pancreatic fistula : a systematic review and meta-analysis15. Phlebotomy resulting in controlled hypovolemia to prevent blood loss in major hepatic resections (PRICE-1) : a feasibility randomized controlled trial16. Pylorus-preserving versus classic pancreaticoduodenectomy : a single-centre retrospective review of total lymph node yield17. An audit and evaluation of appropriateness of intraoperative allogenic red blood cell transfusion in liver surgery : application of 3 decision rules18. A comparison of lymph node ratio with AJCC lymph node status for survival after Whipple resection for pancreatic adenocarcinoma19. Duodenopancréatectomie céphalique (intervention de Whipple) par voie laparoscopique pure20. Use of the Molecular Adsorbent Recirculating System (MARS) in acute liver failure : a multicentre experience21. Barriers to adjuvant chemotherapy after resection for pancreatic cancer22. Comparison of primary and metastatic pancreatic cancer by clinical and genomic features23. Factors associated with invasion and postoperative overall survival in resected IPMN01. Incisional hernia repair surgery improves patient-reported outcomes02. Prospective study of single-stage repair of contaminated hernias with the novel use of calcium sulfate antibiotic beads in conjunction with biologic porcine submucosa tissue matrix03. e-TEP transversus abdominus release04. Umbilical hernias05. Review of 1061 femoral hernias done at the Shouldice Hospital over a period of 6 years01. Metabolic outcomes after bariatric surgery for a provincial Indigenous population02. Outcomes of sleeve gastrectomy performed in a regional hospital03. A longitudinal analysis of wait times in a publicly funded, regionalized bariatric care system04. Concurrent laparoscopic ventral hernia repair with bariatric surgery : a propensity-matched analysis05. Outcomes from explantation of laparoscopic adjustable gastric band : experience from a Canadian bariatric centre of excellence06. Development of consensus-derived quality indicators for laparoscopic sleeve gastrectomy07. Conversion of sleeve gastrectomy to laparoscopic Roux-en-Y gastric bypass in intestinal nonrotation08. The utility of routine preoperative upper gastrointestinal series for laparoscopic sleeve gastrectomy09. Body image concerns, depression, suicidality and psychopharmacological changes in postoperative bariatric surgery patients : a mixed-methods study10. Technical factors associated with early sleeve stenosis after sleeve gastrectomy : an analysis of the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database11. Analysis of complication and readmission rates after laparoscopic sleeve gastrectomy at a single bariatric surgery centre : a retrospective NSQIP study12. Management of common bile duct stones in patients after Roux-en-Y gastric bypass : a systematic review13. Improvement and resolution of urinary incontinence after bariatric surgery : a systematic review and meta-analysis14. Bridging interventions for weight loss prior to bariatric surgery in patients with superobesity : a systematic review and meta-analysis15. Secondary and tertiary learning curves in bariatric surgery16. Achalasia following laparoscopic sleeve gastrectomy : a case report17. Multidisciplinary approach to halving length of stay after bariatric surgery18. Prospective analysis of staple line haemostatic materials in stapled bariatric surgery19. Barriers and facilitators to managing patients with class II and III obesity in primary care : a qualitative study20. The Edmonton Obesity Staging System predicts risk of postoperative complications and mortality following bariatric surgery21. The impact of attention-deficit/hyperactivity disorder on bariatric surgery outcomes : systematic review and meta-analysis22. The effect of bariatric surgery on migraines : a systematic review and meta-analysis23. A population-based matched cohort study of mortality after bariatric surgery24. Safety and outcomes of bariatric surgery performed at an ambulatory site associated with a tertiary care hospital in Canada25. Race and sex predict adverse outcomes following bariatric surgery : a propensity-matched MBSAQIP analysis26. A survey of primary care physician referral to bariatric surgery : access, perceptions and barriers ». Canadian Journal of Surgery 62, no 4 Suppl 2 (août 2019) : S89—S169. http://dx.doi.org/10.1503/cjs.011719.

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Dai, Jianxun, Huimin Yu, Huolin Huang, Taisen Ye, Yun Lei, Nan Sun, Dawei Li, Hao Zheng, Hui Huang et Yung C. Liang. « Recess-free thin-barrier AlGaN/GaN Schottky barrier diodes with ultra-low leakage current : Experiment and simulation study ». Applied Physics Letters 124, no 20 (13 mai 2024). http://dx.doi.org/10.1063/5.0188134.

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In GaN Schottky barrier diodes (SBD), there is a trade-off between the turn-on voltage and the leakage current. In this study, recess-free 4 nm-thin-barrier AlGaN/GaN SBDs with minimal leakage current as well as excellent turn-on voltage homogeneity are developed, which enable better electrical control to pinch off the 2DEG channel under the anode region and avoids trap introduced in the barrier etching process. In detail, the effect of reverse stress on the SBD performance is initially explored by using differential conductance, and then, the anode-to-cathode distances and temperatures dependence of SBDs output characteristics are systematically studied. The fabricated thin-barrier GaN SBDs show a turn-on voltage of ∼0.75 V and a low level leakage current of 9.66 × 10−10 (1.91 × 10−8) A/mm at 300 (423) K, which is among the lowest reported values at the comparable reverse bias voltage and temperature. Moreover, structure parameters of the thin-barrier AlGaN/GaN SBD are systematically modeled and optimized by the TCAD simulations, including anode metal work function, Al mole fraction, the anode-to-cathode distance, and slanted anode angle. The introduction of slanted anode is found to have significant effect on the improvement of reverse breakdown voltage and leakage current characteristics.
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Eriksen, Niklas. « Median clouds and a fast transposition median solver ». Discrete Mathematics & ; Theoretical Computer Science DMTCS Proceedings vol. AK,..., Proceedings (1 janvier 2009). http://dx.doi.org/10.46298/dmtcs.2739.

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International audience The median problem seeks a permutation whose total distance to a given set of permutations (the base set) is minimal. This is an important problem in comparative genomics and has been studied for several distance measures such as reversals. The transposition distance is less relevant biologically, but it has been shown that it behaves similarly to the most important biological distances, and can thus give important information on their properties. We have derived an algorithm which solves the transposition median problem, giving all transposition medians (the median cloud). We show that our algorithm can be modified to accept median clouds as elements in the base set and briefly discuss the new concept of median iterates (medians of medians) and limit medians, that is the limit of this iterate. Le problème de la médiane est de trouver une permutation dont la distance totale à un ensemble donné de permutations (l´ensemble de base) est minimale. C'est un problème important en génomique comparative et il a été étudié pour certaines mesures de distance. La distance de transposition n'est pas directement liée à la biologie, mais il a été démontré que son comportement est similaire à celui des distances biologiques essentielles, et elle peut donc donner des indications sur leurs propriétés. Nous construisons un algorithme qui résout le problème de la médiane pour la transposition, et donne toutes les transpositions médianes (le nuage des médianes). Nous démontrons que notre algorithme peut être modifié pour admettre des nuages de médianes comme éléments de l´ensemble de base et introduisons le concept de médianes itérées (médianes de médianes) et de médianes limites, c-à-d de limites de ces itérations.
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Dabye, AS, DB Ba, A. Diakhaby et GS Lo. « Etude de l’estimateur de la distance minimale pour des modèles de rupture des processus de Poisson : cas avec simulations ». Afrika Statistika 3, no 1 (17 octobre 2009). http://dx.doi.org/10.4314/afst.v3i1.46877.

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Park, Chung Il, Seungah Choe, Woorim Lee, Wonjae Choi, Miso Kim, Hong Min Seung et Yoon Young Kim. « Ultrasonic barrier-through imaging by Fabry-Perot resonance-tailoring panel ». Nature Communications 14, no 1 (28 novembre 2023). http://dx.doi.org/10.1038/s41467-023-43675-4.

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AbstractImaging technologies that provide detailed information on intricate shapes and states of an object play critical roles in nanoscale dynamics, bio-organ and cell studies, medical diagnostics, and underwater detection. However, ultrasonic imaging of an object hidden by a nearly impenetrable metal barrier remains intractable. Here, we present the experimental results of ultrasonic imaging of an object in water behind a metal barrier of a high impedance mismatch. In comparison to direct ultrasonic images, our method yields sufficient object information on the shapes and locations with minimal errors. While our imaging principle is based on the Fabry-Perot (FP) resonance, our strategy for reducing attenuation in our experiments focuses on customising the resonance at any desired frequency. To tailor the resonance frequency, we placed an elaborately engineered panel of a specific material and thickness, called the FP resonance-tailoring panel (RTP), and installed the panel in front of a barrier at a controlled distance. Since our RTP-based imaging technique is readily compatible with conventional ultrasound devices, it can realise underwater barrier-through imaging and communication and enhance skull-through ultrasonic brain imaging.
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Baden, Andrea L., Amanda N. Mancini, Sarah Federman, Sheila M. Holmes, Steig E. Johnson, Jason Kamilar, Edward E. Louis et Brenda J. Bradley. « Anthropogenic pressures drive population genetic structuring across a Critically Endangered lemur species range ». Scientific Reports 9, no 1 (7 novembre 2019). http://dx.doi.org/10.1038/s41598-019-52689-2.

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Abstract In recent decades Madagascar has experienced significant habitat loss and modification, with minimal understanding of how human land use practices have impacted the evolution of its flora and fauna. In light of ongoing and intensifying anthropogenic pressures, we seek new insight into mechanisms driving genetic variability on this island, using a Critically Endangered lemur species, the black-and-white ruffed lemur (Varecia variegata), as a test case. Here, we examine the relative influence of natural and anthropogenic landscape features that we predict will impose barriers to dispersal and promote genetic structuring across the species range. Using circuit theory, we model functional connectivity among 18 sampling localities using population-based genetic distance (FST). We optimized resistance surfaces using genetic algorithms and assessed their performance using maximum-likelihood population-effects mixed models. The best supported resistance model was a composite surface that included two anthropogenic features, habitat cover and distance to villages, suggesting that rapid land cover modification by humans has driven change in the genetic structure of wild lemurs. Primary conservation priority should be placed on mitigating further forest loss and connecting regions identified as having low dispersal potential to prevent further loss of genetic diversity and promote the survival of other moist forest specialists.
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