Littérature scientifique sur le sujet « Direct ethanol metabolithe »
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Articles de revues sur le sujet "Direct ethanol metabolithe"
Werner, Jens, Mouris Saghir, Andrew L. Warshaw, Kent B. Lewandrowski, Michael Laposata, Renato V. Iozzo, Edward A. Carter, Richard J. Schatz et Carlos Fernández-del Castillo. « Alcoholic pancreatitis in rats : injury from nonoxidative metabolites of ethanol ». American Journal of Physiology-Gastrointestinal and Liver Physiology 283, no 1 (1 juillet 2002) : G65—G73. http://dx.doi.org/10.1152/ajpgi.00419.2001.
Texte intégralTong, Ming, Lisa Longato, Quynh-GiaoLy Nguyen, William C. Chen, Amy Spaisman et Suzanne M. de la Monte. « Acetaldehyde-Mediated Neurotoxicity : Relevance to Fetal Alcohol Spectrum Disorders ». Oxidative Medicine and Cellular Longevity 2011 (2011) : 1–13. http://dx.doi.org/10.1155/2011/213286.
Texte intégralChumnanpuen, Pramote, Michael Adsetts Edberg Hansen, Jørn Smedsgaard et Jens Nielsen. « Dynamic Metabolic Footprinting Reveals the Key Components of Metabolic Network in YeastSaccharomyces cerevisiae ». International Journal of Genomics 2014 (2014) : 1–14. http://dx.doi.org/10.1155/2014/894296.
Texte intégralWurst, Friedrich Martin, Sebastian Dresen, John P. Allen, Gerhard Wiesbeck, Marc Graf et Wolfgang Weinmann. « Ethyl sulphate : a direct ethanol metabolite reflecting recent alcohol consumption ». Addiction 101, no 2 (février 2006) : 204–11. http://dx.doi.org/10.1111/j.1360-0443.2005.01245.x.
Texte intégralYonei, Y., H. Wayland et P. H. Guth. « Role of arachidonic acid metabolites in ethanol vasoaction in rat gastric submucosa ». American Journal of Physiology-Gastrointestinal and Liver Physiology 255, no 6 (1 décembre 1988) : G731—G737. http://dx.doi.org/10.1152/ajpgi.1988.255.6.g731.
Texte intégralNzodjou, Thierry Fokou, Jules Clement Nguedia Assob, Joseph Ngoupayo, Bathelemy Ngameni et Jean Emmanuel Mbosso Teinkel. « Quantitative Screening and Study of the in vivo Subchronic Toxicity of Ethanolic Extract from the Stem Bark of Canarium schweinfurthii Engl. (Burseraceae) in Wistar Rats ». Saudi Journal of Medical and Pharmaceutical Sciences 9, no 2 (14 février 2023) : 74–93. http://dx.doi.org/10.36348/sjmps.2023.v09i02.005.
Texte intégralVAN WAVERSVELD, J., A. D. F. ADDINK et G. VAN DEN THILLART. « Simultaneous Direct and Indirect Calorimetry on Normoxic and Anoxic Goldfish ». Journal of Experimental Biology 142, no 1 (1 mars 1989) : 325–35. http://dx.doi.org/10.1242/jeb.142.1.325.
Texte intégralHajjar, J. J., E. R. Baker, D. M. Renison, P. W. Gardner, R. Zirin et T. K. Tomicic. « Effect of ethanol on choline transport in rat jejunum ». American Journal of Physiology-Gastrointestinal and Liver Physiology 249, no 2 (1 août 1985) : G177—G183. http://dx.doi.org/10.1152/ajpgi.1985.249.2.g177.
Texte intégralSanvisens, Arantza, Neus Robert, José Hernández, Paola Zuluaga, Magí Farré, Wifredo Coroleu, Montserrat Serra, Jordi Tor et Robert Muga. « Alcohol Consumption during Pregnancy : Analysis of Two Direct Metabolites of Ethanol in Meconium ». International Journal of Molecular Sciences 17, no 3 (22 mars 2016) : 417. http://dx.doi.org/10.3390/ijms17030417.
Texte intégralWurst, Friedrich Martin, Gregory E. Skipper et Wolfgang Weinmann. « Ethyl glucuronide-the direct ethanol metabolite on the threshold from science to routine use ». Addiction 98 (14 novembre 2003) : 51–61. http://dx.doi.org/10.1046/j.1359-6357.2003.00588.x.
Texte intégralThèses sur le sujet "Direct ethanol metabolithe"
MORINI, Luca. « Development and validation of analytical methods for the determination of direct ethanol metabolites in biological matrices by liquid chromatography tandem mass spectrometry. Applications in forensic toxicology ». Doctoral thesis, 2009. http://hdl.handle.net/11562/337365.
Texte intégralAlcohol abuse and misuse is a growing problem with relevant clinical, social, economic and administrative implications. A sensitive and specific diagnosis of the different forms of acute and chronic alcohol abuse is an essential tool to properly face this social burden. Recently, the determination of two minor non oxidative products of alcohol metabolism, ethyl glucuronide (EtG) and ethyl sulphate (EtS), in traditional (blood and derivatives, urine) as well as alternative (hair, meconium) biological matrices has been proposed as a promising approach to the efficient and effective diagnosis of alcohol abuse for forensic, clinical, and epidemiological purposes. The aim of this thesis was to (a) develop and fully validate analytical methods for the determination of these two metabolites in different biological samples (urine, blood/serum, meconium and, for EtG, hair) by liquid chromatography-tandem mass spectrometry (LC-MS/MS), and b) to apply these methods in several diagnostic contexts and, in particular: 1) the study of the blood kinetics and blood/serum ratio of EtG and EtS in samples of heavy drinkers at the beginning of a withdrawal treatment (study carried out in collaboration with the Norwegian National Institute of Health); 2) study of the stability of EtG and EtS in post-mortem samples several years after burial; 3) evaluation of EtG in hair (HEtG) as a potential marker of chronic alcohol abuse, in comparison with other biomarkers currently used in the routine (i.e. CDT); 4) application of EtG and EtS in meconium as markers of gestational alcohol exposure. Results obtained in the different fields mentioned above showed, in some cases for the first time, or confirmed the great potential of EtG and EtS as sensitive and specific markers of alcohol misuse. Moreover they allowed to ascertain that: the elimination of EtG and EtS in heavy drinkers is similar to that occurring in social drinkers (with the important exception of subjects suffering from renal pathologies where the ethanol metabolism and consequently the metabolites elimination appear to be slowed down); EtG and EtS are to mainly distributed in serum than in blood cells, with relevant implications when the analysis is carried out on serum/plasma instead of whole blood; EtG and EtS are detectable in post-mortem biological samples even when collected several years after death; the use of an analytical, sensitive (LLOQ of 3 pg/mg), specific and fully validated method gives to HEtG a high diagnostic sensitivity and specificity; HEtG appears to qualitatively correlate with other markers ( i.e. cocaethylene in hair of cocaine users; CDT), although it exhibits better sensitivity (>90%) in ascertaining alcohol chronic abuse; EtG and EtS are detectable in meconium (even if their concentration doesn’t correlate with that of other markers of alcohol consumption such as fatty acids ethyl esters), thus offering the basis for an in-depth evaluation of the usefulness of their determination in this matrix for the diagnosis of prenatal exposure to alcohol.
Chapitres de livres sur le sujet "Direct ethanol metabolithe"
Wurst, Friedrich Martin, Joerg Metzger, Katja Jachau, Stephan Seidl, Lutz Pridzun, Ines Janda et Andreas Alt. « The direct ethanol metabolite ethyl glucuronide : A specific marker of recent alcohol consumption ». Dans New and Upcoming Markers of Alcohol Consumption, 62–74. Heidelberg : Steinkopff, 2001. http://dx.doi.org/10.1007/978-3-642-96008-6_5.
Texte intégralWorrall, Simon. « Proteins modified by direct and indirect ethanol metabolites, and their associated antibodies, as markers of alcohol intake ». Dans New and Upcoming Markers of Alcohol Consumption, 93–110. Heidelberg : Steinkopff, 2001. http://dx.doi.org/10.1007/978-3-642-96008-6_7.
Texte intégralProescholdt, Margit G., et Marc Walter. « Endocrinology and alcohol ». Dans Oxford Textbook of Endocrinology and Diabetes, 294–300. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.2254.
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