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Littérature scientifique sur le sujet « Diagnosi clinica »

Auteur : Grafiati
Publié le 9 mars 2023
Mis à jour le 10 mars 2023

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Articles de revues sur le sujet "Diagnosi clinica"

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Pispero, Alberto, Sem Decani, Federico Scotti, Laura Moneghini, Elena Vegni, Daniela Sorrentino, Alberto Saibene et Andrea Sardella. « Presentazione clinica e diagnosi ». Dental Cadmos 89, no 02 (février 2021) : 1. http://dx.doi.org/10.19256/d.cadmos.02.2021.13.

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Tiratterra, Fabrizio, Valeria Pignatelli, Alberto Placido, Agostino Valenti et Umberto Recine. « Utilità dell’autopsia in Medicina Interna : discrepanze tra diagnosi clinica e diagnosi autoptica ». Italian Journal of Medicine 6, no 4 (décembre 2012) : 307–10. http://dx.doi.org/10.1016/j.itjm.2011.10.006.

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Lingiardi, Vittorio, et Annalisa Tanzilli. « La diagnosi psicodinamica in un'ottica contemporanea ». RICERCA PSICOANALITICA, no 3 (octobre 2011) : 9–31. http://dx.doi.org/10.3280/rpr2011-003002.

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I più diffusi manuali di classificazione diagnostica come l' (ICD; vedi World Health Organization, OMS, 1992) e il (DSM; vedi American Psychiatric Association, APA, 2000), nelle loro varie edizioni, si fondano su un approccio alla psicopatologia descrittivo, ateorico e sostanzialmente . Questa impostazione ha suscitato nei clinici di formazione dinamica reazioni diverse: disinteresse, insoddisfazione, diffidenza, ostilità. La recente comparsa di procedure di valutazione e manuali diagnostici di ispirazione psicodinamica, ma ben ancorati alla ricerca empirica, quali la (SWAP-200; Westen, Shedler, 1999a,b; Westen, Shedler, Lingiardi, 2003) e il (PDM; PDM Task Force, 2006) ha promosso una "rivoluzione culturale" nella comunità dei professionisti della salute mentale, valorizzando un approccio alla diagnosi più vicino alla pratica clinica e più compatibile con interventi di tipo psicoterapeutico. Dove la diagnosi non è solo un'etichetta, ma anche un processo valutativo capace di ricondurre il sintomo al contesto di personalità e a un trattamento a misura di paziente.
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Brizzolara, Paola. « Qualche considerazione su processo diagnostico e lavoro analitico, alla luce dell'attuale interesse per la valutazione dimensionale ». RICERCA PSICOANALITICA, no 3 (octobre 2011) : 33–41. http://dx.doi.org/10.3280/rpr2011-003003.

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Gli strumenti diretti a formulare la diagnosi secondo una logica dimensionale, come il PDM, indirizzano il ragionamento diagnostico non solo ad accogliere la soggettività del paziente, ma avvalendosi di un impianto epistemologico nutrito dalle logiche della Complessità e dal costruttivismo, promuovono il riconoscimento della diade pazienteterapeuta quale vertice osservativo del campo diagnostico. In tal senso, il lavoro della diagnosi presenta un'opportunità sia per estendere e rendere più raffinata la concettualizzazione del ruolo dell'analista, sia per riflettere su come i dati che emergono dalla valutazione possono essere impiegati nella pratica clinica. In particolare, attraverso la presentazione di una situazione clinica, è evidenziata l'importanza di una valutazione clinica aperta alla riformulazione lungo il lavoro terapeutico, per cogliere le nuove possibilità emergenti dal campo analitico nel momento presente, capace di comprendere e utilizzare le manovre implicite che il paziente mette in atto nella relazione terapeutica, alla ricerca dell'espansione della propria soggettività.
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Gernone, Giuseppe, Francesco Papagno, Vito Pepe et Francesco Soleti. « Insufficienza renale acuta del postpartum : una diagnosi complessa ? » Giornale di Clinica Nefrologica e Dialisi 25, no 1 (3 novembre 2013) : 26–31. http://dx.doi.org/10.33393/gcnd.2013.998.

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La diagnosi differenziale nei casi d'insufficienza renale acuta del postpartum associata ad anemia emolitica microangiopatica e trombocitopenia, include, tra le altre: pre-clampsia grave/eclampsia, grave eclampsia, la sindrome HELLP (Hemolysis, Elevated Liver enzyme, Low Platelet), la acute fatty liver of pregnancy (AFLP), la porpora trombotica trombocitopenica/sindrome emolitico-uremica associata alla gravidanza (TTP/aHUS), esordio acuto o flare di LES in gravidanza e la sindrome catastrofica da anticorpi antifosfolipidi (CAPS). Si tratta di condizioni potenzialmente pericolose per la vita data la presenza di disfunzione multiorgano. Il verificarsi di uno stato di ipercoagulabilità e la concentrazione decrescente di ADAMTS 13 in gravidanza e nel post-parto aumentano il rischio di sviluppare porpora trombotica trombocitopenica (TTP). Vi è però una notevole sovrapposizione riguardo la clinica ed i test di laboratorio tra queste condizioni, e quindi la diagnosi può essere un problema anche per clinici esperti. Tuttavia è importante stabilire un'accurata diagnosi poiché la gestione e le complicanze di tali sindromi possono essere differenti. Il caso presentato sottolinea la complessità connessa alla diagnosi differenziale dei quadri clinici che includono anemia emolitica microangiopatica e trombocitopenia connessi alla gravidanza ed il ruolo del plasma exchange nella loro gestione.
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Pereira, Roberto. « Verso una diagnosi relazionale della schizofrenia ». RIVISTA DI PSICOTERAPIA RELAZIONALE, no 51 (août 2020) : 20–39. http://dx.doi.org/10.3280/pr2020-051003.

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Il rapporto tra la psicopatologia, o meglio, tra la diagnosi psicopatologica, o la psicologia clinica, e la terapia familiare (TF) è comples-so, e si è modificato nel corso del tempo, in base ai cambiamenti che si sono verificati nella TF a partire dalla sua nascita. Questo articolo descrive le due anime che la TF ha sempre manifestato, una contraria e una a favore dell'uso delle diagnosi, rappresentate da Gregory Ba-teson e da Don Jackson, i quali, pur condividendo lo studio della comunicazione tra i pazienti schizofrenici e le loro famiglie, avevano un approccio molto differente ai problemi relazionali e/o psicologici o psichiatrici. La nostra posizione è decisamente favorevole all'uso delle diagnosi, proponendo però un nuovo linguaggio diagnostico relazionale che possa sostituire l'altrimenti inevitabile linguaggio psicopatologico tradizionale. Si propone, in conclusione, una diagnosi dimensionale e relazionale della schizofrenia, basata sulle caratteristiche relazionali descritte in queste famiglie, che permette di definire meglio le aree d'intervento e di analizzare l'evoluzione dell'intervento terapeutico.
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Digilio, M. Cristina. « Sindromi genetiche sottese alla disabilitŕ cognitiva grave ». CHILD DEVELOPMENT & ; DISABILITIES - SAGGI, no 3 (avril 2012) : 73–78. http://dx.doi.org/10.3280/cdd2010-003012.

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L'eziologia della disabilitŕ cognitiva grave č molto complessa, tanto che la causa di questa condizione clinica rimane ancora oggi non identificabile nel 40% circa dei casi. L'inquadramento diagnostico č perň un'esigenza concreta delle famiglie, per tentare di avere piů informazioni possibili sulla prognosi della patologia, sulle possibilitŕ e metodi terapeutici piů appropriati, sui rischi di ricorrenza familiare. I metodi utilizzati per l'inquadramento diagnostico sono di tipo clinico, strumentale e laboratoristico citogenetico-molecolare. Dal punto di vista clinico l'approccio prevede la ricostruzione dell'anamnesi familiare, la raccolta di dati sul decorso della gravidanza, sul periodo neonatale e sulla storia clinica dalla nascita al momento dell'osservazione. Si stima che il 4-35% (in media 15%) dei casi di disabilitŕ cognitiva sia riconducibile ad eziologia cromosomica. Le tecniche di citogenetica molecolare sono progressivamente migliorate negli ultimi anni, con la possibilitŕ di aumentare la sensibilitŕ di diagnosi per le sindromi da microanomalia cromosomica (con la tecnica CH-Array). La sindrome dell'X fragile costituisce una delle piů frequenti cause di disabilitŕ cognitiva nei soggetti di sesso maschile, specialmente nei casi a ricorrenza familiare della patologia. Il numero delle sindromi monogeniche associate a disabilitŕ cognitiva č altissimo, e si tratta sempre di patologie singolarmente rare. In questo ambito č importante saper identificare caratteristiche cliniche che possano orientare verso una patologia specifica, allo scopo di poter ipotizzare una diagnosi clinica ed eventualmente mirare i test genetici nei casi di sindromi ad eziologia attualmente nota. Sono utili, in questo ambito, il riscontro di dismorfie particolari orientative per una sindrome specifica, la caratterizzazione anatomica delle malformazioni associate o l'eventuale presenza di epilessia, la definizione di un fenotipo comportamentale e cognitivo specifico. Č importante anche la rivalutazione clinica nel tempo, per cogliere segni di significato diagnostico che possono comparire in etŕ diverse della vita di un bambino.
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Robert, Elisabetta, Graziella Sinaccio et A. G. Spagnolo. « Bioetica e nursing : Il ruolo dell'infermiere nella sperimentazione clinica ». Medicina e Morale 42, no 3 (30 juin 1993) : 575–84. http://dx.doi.org/10.4081/mem.1993.1057.

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Gli Autori considerano i problemi etici che l'infermiere può incontrare durante l'attivazione e lo svolgimento delle sperimentazioni cliniche. Alla luce dei principi di Bioetica vengono affrontati l'informazione, il consenso, la comunicazione della diagnosi, il rapporto medico/infermiere/paziente, il coinvolgimento delle famiglie, la qualità della vita, il Comitato Etico, che costituiscono importanti temi di riflessione critica e rappresentano altresì problematiche delicate con le quali l'infermiere deve spesso confrontarsi nella ricerca e nella vita di corsia.
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Cannao, M. « Comunicare la diagnosi di minorazione congenita ». CHILD DEVELOPMENT & ; DISABILITIES - SAGGI, no 1 (octobre 2009) : 98–112. http://dx.doi.org/10.3280/cdd2009-001008.

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- Vengono prese in esame le reazioni dei genitori alla diagnosi di minorazione congenita del figlio, con specifico riferimento alla minorazione visiva (cecitŕ o ipovisione). Di tali reazioni, inevitabilmente connotate da grande sofferenza, č necessario tener conto quando si comunica la diagnosi, in modo da aiutare i genitori a superare il trauma e riattivare in loro la fiducia e la speranza. Affinché ciň sia possibile la comunicazione deve essere concepita come tappa iniziale di un processo di aiuto da prolungare per tutto il periodo di degenza ospedaliera della madre e del neonato e anche dopo la dimissione. I protagonisti di questo processo sono sia il medico (al quale spetta il compito dell'informazione clinica) sia tutti gli altri operatori sanitari (che devono fornire un costante sostegno), sia i genitori stessi. Una diagnosi comunicata con rispetto, partecipazione, solidarietŕ, competenza, prepara il terreno per la costruzione del legame di attaccamento con il figlio minorato e risparmia ai genitori l'ulteriore sofferenza di non sentirsi compresi e accolti in una delle fasi piů drammatiche della loro vita.Parole chiave minorazione congenita, cecitŕ, ipovisione, diagnosi, comunicazione
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Borgna, Eugenio. « Le fragili certezze della diagnosi in psichiatria ». RIVISTA SPERIMENTALE DI FRENIATRIA, no 2 (juillet 2011) : 11–18. http://dx.doi.org/10.3280/rsf2011-002002.

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Nel contesto di una psichiatria rivalutata come scienza umana, come scienza della intersoggettivitŕ, e non solo come scienza naturale che la comprende solo in parte, la diagnosi non puň essere considerata nella sua ghiacciata e impersonale dimensione categoriale; ma deve essere riconsiderata nella sua dimensione problematica e interpersonale. Questo cosa significa in un contesto di psichiatria applicata alla clinica e alla riconoscibilitŕ dei molteplici fenomeni della sofferenza psichica: definizione radicalmente antropologica, e non drasticamente naturalistica come č quella di malattia tout court? Non altro significa che, in psichiatria, come ha scritto una volta per tutte Kurt Schneider, i sintomi non hanno nulla a che fare con la loro riduzione naturalistica a segmenti pietrificati di una malattia in senso clinico; ma con esperienze vissute che narrano qualcosa di significativo storicamente, e soggettivamente, e che conseguentemente non possono se non essere interpretati. Non esistono fatti, ma interpretazioni di fatti, come ha scritto Friedrich Nietzsche; e cosě la diagnosi, in psichiatria, e cioč la connotazione neurotica, o psicotica, dei sintomi (la sola cosa che, in fondo, conti), cambia nella misura in cui nasca, o non nasca, una relazione terapeutica fra chi cura e chi č curato. La diagnosi, insomma, come esperienza, e non come pietrificata espressione di un incasellamento dei diversi sintomi in uno schema sindromico precostituito.
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Thèses sur le sujet "Diagnosi clinica"

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Turrini, Mauro. « La clinica nel laboratorio. Etnografia dell'incertezza nella diagnosi prenatale ». Doctoral thesis, Università degli studi di Padova, 2009. http://hdl.handle.net/11577/3426442.

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CLINICS IN THE LABORATORY An ethnography of uncertainty in prenatal diagnosis The research is an empirical investigation of scientific and medical uncertainty in the context of prenatal diagnosis. Combining sociology and anthropology of health with social studies of science and technology, its aim is to scrutinize the interaction between medicine and science in a clinical arena characterized by the fundamental role of scientific activity within the clinical laboratory. Modern medicine has evolved to a point where diagnostic judgements based on subjective evidence are progressively being supplanted by judgements based on objective evidence provided by laboratory procedures. Representing a typical example of geneticization of medicine, prenatal diagnosis is a pregnancy test based on devices and knowledge of genetics and, more specifically, cytogenetics. The hybrid character of prenatal diagnosis makes prenatal cytogenetic laboratories particularly uncertain and controversial. On the one hand, the role of laboratory data makes the scientific work critical in the process of decision-making. On the other hand, the scientific context of a cytogenetics laboratory is shaped and moulded by cultural, existential, juridical meanings, particular to clinical culture. Theoretically, this investigation draws upon the recent dialogue between two sociological disciplines illuminating their intersection and developing a new, innovative category in the sociology of medical science and technology. Uncertainty has been largely ignored or denied by medicine and science because of rationalist training and attitude. Social sciences’ scrutiny of work practices has demonstrated the distance between how these disciplines work in practice and the rhetoric of the official literature. Thus, the primary rationale of the methodological approach, which is inspired by qualitative analysis. In particular, the data came from ethnographic observations of the daily routines of physicians, biologists and technologists combined with informal and in-depth interviews of professionals as well as analysis of scientific documents such as articles, guidelines, protocols, and manuals The empirical analysis is structured in two main parts. First, a micro-social analysis is focused on laboratory procedures of manipulation and interpretation of biological samples. Uncertainty is a pervasive phenomenon which dominates the work practice of laboratory since it informs not only know-hows and professional identities, but also standardization programmes. Second, the analysis involves the articulation between the different social worlds which are part of the biomedial network. Comparing prenatal diagnosis to other biomedical platforms such as oncoematology, it demonstrates that uncertainty is embedded in the relationships between medical and scientific components. The suggestion is that the source, character, and amount of uncertainty is not merely technical, but it is negotiated and flexible. The social nature of uncertainty also means a more ambiguous definition of it. In fact, uncertainties are not merely a threat to practice, but they are also a resource which affords negotiation between identities of the different components of biomedical networks.
LA CLINICA NEL LABORATORIO Etnografia dell’incertezza nella diagnosi prenatale La ricerca prende le mosse dall’analisi empirica di un’area specifica della medicina, la diagnosi prenatale, caratterizzata dal ruolo fondamentale della componente scientifica di laboratorio, allo scopo di analizzare l’incertezza, un tema che accomuna sia gli studi sociali della salute che quelli della scienza e della tecnologia. Frutto della tendenza secolare, tipica della medicina moderna, ad inglobare saperi e strumenti aventi una genealogia scientifica, tale ambito medico rappresenta un caso esemplare di applicazione in campo sanitario di strumenti della scienza genetica e, più specificatamente, delle tecniche di analisi citogenetica. Il lavoro svolto dal laboratorio di citogenetica, una volta assunto un ruolo centrale in ambito sanitario, pur essendo fortemente caratterizzato dalla propria origine scientifica, risulta permeato e modellato da significati culturali e giuridici peculiari della medicina prenatale. Lo sforzo teorico è diretto a rielaborare prospettive analitiche su un argomento non certo nuovo, a partire dal dialogo tra due tradizioni sociologiche che, pur essendo state a lungo distanti, sembrano ora aver trovato diversi punti di contatto. Concepita dapprima in relazione ai processi decisionali medici, l’incertezza acquisisce successivamente una nuova centralità sociologica grazie allo studio empirico del lavoro scientifico, che dimostra il profondo iato tra la scienza che esiste in pratica e la scienza descritta nella letteratura. Da qui discende la scelta di un metodo ispirato a strumenti propri dell’indagine qualitativa, quali l’osservazione partecipante e l’intervista in profondità, orientati ad esplorare la dimensione lavorativa quotidiana nei diversi contesti medici e scientifici che compongono il network biomedico della diagnosi prenatale. Essendo rivolta unicamente al punto di vista dei professionisti, la ricerca si è svolta attraverso una graduale opera di avvicinamento alla prospettiva degli osservati, a partire dallo studio teorico della letteratura medico-scientifica di riferimento, dagli strumenti operativi quali le linee-guida e i protocolli, sino ad arrivare allo scambio di vedute in occasione della presentazione in un convegno scientifico di genetica. L’ibridizzazione tra medicina e scienza enfatizza un tratto comune alle pratiche di entrambi gli ambiti disciplinari, l’incertezza, studiata empiricamente da un duplice punto di vista. In primo luogo, si privilegia una prospettiva microsociale concentrata a ricostruire le strategie di addomesticamento dell’incertezza nella processazione e nell’interpretazione dei campioni biologici. Si intende così dimostrare come la pervasività dell’incertezza penetri in maniera costitutiva nel processo di soggettivazione professionale dei citogenetisti, nelle metodiche di analisi e, infine, nei programmi di standardizzazione. In secondo luogo, si allarga il campo di indagine all’articolazione delle diverse componenti che costituiscono tale piattaforma biomedica, comparandole con altre aree biomediche quali l’oncoematologia. Sia nelle relazioni tra i diversi elementi che compongono il laboratorio sia nelle relazioni tra i contesti medici e quelli scientifici, l’incertezza appare un fenomeno non esclusivamente di tipo tecnico, ma frutto di una percezione e di rappresentazioni che partecipano alla formazione tanto della cultura di un ambiente lavorativo quanto dello status professionale di chi vi lavora. L’incertezza risulta essere non solo un ostacolo, derivato dall’applicazione contestuale di regole generali, ma anche una risorsa di natura sociale, essenziale nell’articolare gli elementi eterogenei appartenenti ad una stessa rete.
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Calzolari, Claudia <1976&gt. « Diagnosi e prognosi molecolare nel linfoma canino ». Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2007. http://amsdottorato.unibo.it/92/1/definitiva_per_PDF_claudia.pdf.

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Calzolari, Claudia <1976&gt. « Diagnosi e prognosi molecolare nel linfoma canino ». Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2007. http://amsdottorato.unibo.it/92/.

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Storni, Elisa <1970&gt. « Applicazione di metodi molecolari nella diagnosi di alcune infezioni batteriche ». Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2007. http://amsdottorato.unibo.it/36/1/tesi_Storni.pdf.

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Storni, Elisa <1970&gt. « Applicazione di metodi molecolari nella diagnosi di alcune infezioni batteriche ». Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2007. http://amsdottorato.unibo.it/36/.

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SALA, FRANCESCA CHIARA. « La comunicazione della diagnosi di tumore ai bambini : tre studi ». Doctoral thesis, Università degli Studi di Milano-Bicocca, 2017. http://hdl.handle.net/10281/168701.

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An effective communication to children lead to a lower incidence of long-term psychopathological implications, such as lower levels of anxiety and distress, increases the child’s sense of control on the illness and furthers the expression of fears, suffers and anguishes. Moreover an effective diagnosis communication promotes the development of a trustful relationship between the physician and the child, a closer adherence to therapies and a consequently, and therefore bigger chance of healing, but also a higher quality of life and a lower incidence of relapses. Cancer can be defined as a “systemic” illness, that affect the all family; the psycological consequences of cancer diagnosis communication are similar for the ill child, parents and siblings, even when the child is a son of ill parents. In western medical culture a direct and clear communication of diagnosis, prognosis and treatment both to the child and the parents is considered to be a principle and above all a duty. However, it is well known from the literature that the communication process is strongly dependent from factors related to the cultural background, from the hospital environment and from the personal communicative style of each member of hospital staff. This manuscript describes three case studies which were performed and managed during a PhD. These research had the goal of investigate the topic of the diagnosis communication from different point of view, focusing on the ones from the parents of sick children, from the doctor and from parents affected by cancer. The aim of these studies was to identify the most common procedures used in different Italian hospitals and shed light on their effectiveness or disfunctions; the parents satisfaction was evaluated with reference to the diagnosis communication delivered to themselves and their children, both as parents of sick children and patients with children. Particular attention was given to physicians’ feelings and their communication skills as well as to the role of psychologists, the relationship with them and how these factors could influence the satisfaction level expressed.
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CAMERONI, IRENE. « Tumore e gravidanza. Diagnosi, trattamento e outcome, l'esperienza della clinica ostetrico ginecologica di Monza ». Doctoral thesis, Università degli Studi di Milano-Bicocca, 2011. http://hdl.handle.net/10281/19597.

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BACKGROUND The exact incidence of cancer during gestation is yet to be determined but it is estimated that cancer occurs in 1 in 1000 pregnancies. The most common cancers in pregnancy are those with a peak incidence during the woman‘s reproductive period such as cancer of the breast and cervix, lymphoma, leukemia and melanoma. Cancer during pregnancy is a challenge about assistance and therapy, the aim of therapy in pregnancy is to give optimal treatment to the mother without harm to the fetus. After cancer diagnosis there are following problems such as the difficulty to stage it according usual criteria, the need to planner differentiated treatment, the need to delay or modify treatment in order to preserve the fetus, the risk of teratogenic effects of chemotherapy, the risk of fetal prematurity and so on. The aim of this study was to analyze the pregnancy outcome in a group of patients whit diagnosis of several malignancies during pregnancy. METHODS We retrospectively analyzed 34 patients who have been treated during pregnancy or after delivery because of several malignancies. Cancer was diagnosed at the moment of obstetric visit and all the patients were staged according to standard criteria pregnancy permitting. Serial visits were done by Oncologist and Obstetrician at the same time to take the relationship between pregnant state, cancer and therapeutic choices into account. Chemotherapy, when useful, was started in the second trimester. In all cases were done fetal monitoring and prematurity complications prophylaxis at viability age. Gestational age at delivery was established according to disease state and fetal risk of prematurity. Was avoided the neonatal spinal marrow aplasia attending two weeks from last chemotherapy course. Placental histology was studied in all cases about the presence of cancer cell or chemotherapy effect. RESULTS Surgery during pregnancy was performed in 27% of cases. Chemotherapy during pregnancy was given in 48% of cases. There were not cases of preeclampsia or stillbirth. 73% of patients delivered before 37 weeks of gestation, of them 42% delivered before 34 weeks of gestation in order to begin a therapy not indicated in pregnancy. The incidence of cesarean section was 73%. The incidence of neonates small for gestational age was 12%. There were not cases of congenital malformations. There were not cases of metastatic involvement of placenta. The neonatal outcome evaluated within 1 year from birth was good in all cases. The maternal mortality was 33% between 3-5 years after delivery. CONCLUSIONS Our data are in conformity with the Literature about the possibility to continue the pregnancy when cancer diagnosis. The possibility to receive in pregnancy chemotherapy in selected cases as standard of care is the assumption to have the same survival between the patients that interrupt the pregnancy and who not. According to advancement of perinatal care is possible to do delivery early, treating the patient with the therapy controindicated in pregnancy, without important complications after 32 weeks of gestation. All neonates had good outcome and follow-up, however the prematurity (69% advanced stage vs 25% early stage) was conditioned by cancer stage at the moment of diagnosis. In conclusion, the most important thing is to follow these patients into Specialized Hospital, taking care the cancer and the pregnancy at the same time.
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Camiletti, Sara. « Realtà Aumentata : sviluppi, applicazioni e contributi nella pratica clinica ». Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/24516/.

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La Realtà Aumentata è una tecnica di visualizzazione innovativa che, negli ultimi anni, ha subito un importante sviluppo grazie alla crescita tecnologica che caratterizza questo periodo; gli ambiti in cui ha trovato applicazione sono tra i più svariati, tra questi è possibile annoverare l’ambito educativo, militare, medico e molti altri. Lo scopo di questo elaborato è quello di mettere in risalto come l’ AR si sia sviluppata a partire dalle sue origini evidenziando gli strumenti, sia hardware che software, utilizzati per la sua implementazione e come questi si siano evoluti in risposta ad esigenze diverse degli utilizzatori dando particolare risalto al settore medico-sanitario che ha mostrato un interesse sempre più importante verso questa tecnologia. Verranno analizzate alcune tra le più innovative applicazioni di questa tecnica che hanno determinato una svolta nel trattamento dei pazienti mettendone in risalto le potenzialità sia in ambito diagnostico che terapeutico. Inoltre, sono stati identificati alcuni ambiti in cui la Realtà Aumentata non ha ancora trovato applicazione ma nei quali sarebbe in grado di garantire notevoli contributi alla pratica clinica favorendo il trattamento dei pazienti; nello specifico, data la sua alta diffusione nel mondo, verrà analizzata la patologia del rene policistico, verrà poi esaminato l’effetto dell’ AR sulla valutazione e il trattamento delle aritmie cardiache e infine, lo sviluppo più innovativo valutato riguarda la possibilità di realizzare un sistema di visualizzazione dinamica e tridimensionale per l’atrio; verrà analizzata l’implementazione del codice utilizzato per realizzare i modelli tridimensionali per ciascuna di queste applicazioni ed i risvolti clinici, sia sul paziente, sia sulla prassi clinica che la Realtà Aumentata permetterebbe di conseguire.
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GRIONI, ANDREA. « Application of modern data science to genomics and clinical research ». Doctoral thesis, Università degli Studi di Milano-Bicocca, 2020. http://hdl.handle.net/10281/279991.

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Dopo che il progetto sul genoma umano è stato completato nell'aprile del 2003, il flusso continuo di nuovi database e dati di sequenziamento ha iniziato a trasformare il campo della genomica in scienza basata sui dati. La bioinformatica analizza i dati sperimentali grezzi con l'obiettivo di ottenere informazioni che descrivono le condizioni biologiche misurate, fornendo così un potente strumento per studiare specifici meccanismi molecolari e genetici. Questa conoscenza deve essere combinata con la genomica per decifrare le interrelazioni tra geni, elementi regolatori, vie metaboliche e interazioni proteiche. L'apprendimento profondo, conosciuto come Deep Learning, e’ una sottodisciplina dell'apprendimento automatico, è stato recentemente applicato al campo della genomica, portando a risultati notevoli. I due obiettivi principali di questo lavoro sono: lo sviluppo e le applicazioni di strumenti bioinformatici che consentano lo studio delle basi genetiche della leucemia linfoblastica acuta e l'uso di tecniche di apprendimento profondo per l'identificazione di piccoli elementi di RNA non codificanti del genoma umano. Questa tesi fornisce al lettore una panoramica completa della recente evoluzione della genomica come campo interdisciplinare di ricerca strettamente connesso con l'informatica e l'analisi dei dati.
After the completion of the human genome project in April 2003, the continuous flow of sequencing data and the development of new databases began to transform the field of genomics into data-driven science. Bioinformatics analyses raw experimental data with the aim to obtain information describing biological processes, thus providing a powerful tool to investigate specific molecular and genetic mechanisms. This domain knowledge in combination with genomics allows to decipher the interrelationships between genes, regulatory elements, metabolic pathways, and protein interactions. Deep learning, a subdiscipline of machine learning, has been recently applied to the field of genomics, leading to remarkable results. The two main objectives of this study were: the development and application of bioinformatic tools for the study of the genetic basis of acute lymphoblastic leukaemia, and the usage of deep learning techniques for the identification of small non-coding RNA elements in the human genome. This dissertation provides a comprehensive overview of the recent evolution of genomics as an interdisciplinary field of research strongly associated with computer science and data analysis.
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PAVIA, Laura. « Valutazione di un rolling group ambulatoriale per pazienti con diagnosi di abuso da cocaina ». Doctoral thesis, Università degli Studi di Palermo, 2014. http://hdl.handle.net/10447/90887.

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Lo studio utilizza un disegno longitudinale a misure ripetute per la valutazione process-outcome di un rolling groups psicodinamico per pazienti con diagnosi di abuso di cocaina. La terapia condotta su 18 pazienti è stata effettuata all’interno del Centro Clinico Cocainomani dell’ASP di Brescia. Gli strumenti utilizzati sono: DAST-20, OQ-45, DSQ, CALPAS Group, GMLCS. Le analisi condotte attraverso il Multilevel Models evidenziano dei miglioramenti attendibili sia rispetto al sintomo che riguardo al funzionamento psicologico e all’assetto difensivo. La lunghezza della partecipazione alla terapia e la stabilità del gruppo influenzano l’esito. I pazienti che restano di più in trattamento sperimentano una maggiore qualità delle relazioni all’interno del gruppo. Diversamente l’alleanza dell’individuo è influenzata dalle modificazioni del legame del gruppo nel corso del tempo.
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Livres sur le sujet "Diagnosi clinica"

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1949-, Doherty John, dir. Clinical examination in rheumatology. London : Wolfe Pub. Ltd., 1992.

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Clinical radiology : The essentials. 2e éd. Baltimore : Williams & Wilkins, 1999.

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Clinical radiology : The essentials. Baltimore : Williams & Wilkins, 1993.

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General sonography : A clinical guide. St. Louis : Mosby, 1995.

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Hennessey, Iain, Alan Japp et Robertson Colin. Macleod's clinical diagnosis. Sous la direction de Macleod John 1915-. Edinburgh : Churchill Livingstone/Elsevier, 2013.

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Jevon, Phil, dir. Clinical Diagnosis. Oxford, UK : Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9781444340051.

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Clinical diagnosis. Chichester, West Sussex : Wiley-Blackwell, 2011.

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Clinical imaging : With skeletal, chest, and abdomen pattern differentials. St. Louis : Mosby, 1999.

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Marchiori, Dennis M. Clinical imaging : With skeletal, chest, and abdomen pattern differentials. 2e éd. St. Louis : Elsevier/Mosby, 2005.

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Clinical imaging : An atlas of differential diagnosis. 2e éd. Gaithersburg, Md : Aspen Publishers, 1992.

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Chapitres de livres sur le sujet "Diagnosi clinica"

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Zanello, M., S. Pintaudi, C. Testoni et M. Vincenzi. « Diagnosi clinica e strumentale di morte encefalica ». Dans Il neuroleso grave, 161–74. Milano : Springer Milan, 2010. http://dx.doi.org/10.1007/978-88-470-1460-2_18.

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Chin, Tom D. Y. « Diagnostic Criteria and Differential Diagnosis ». Dans Clinical Topics in Infectious Disease, 117–25. New York, NY : Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-6376-7_10.

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Nicholls, R. J. « Clinical diagnosis ». Dans Topics in Colorectal Disease, 128–31. Berlin, Heidelberg : Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76281-9_16.

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Hongjun, LI, et LI Ning. « Clinical Diagnosis ». Dans Radiology of Influenza A (H1N1), 23–24. Dordrecht : Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6162-9_8.

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García-Elorriaga, Guadalupe, et Guillermo del Rey-Pineda. « Clinical Diagnosis ». Dans Practical and Laboratory Diagnosis of Tuberculosis, 7–18. Cham : Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-20478-9_2.

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Peixoto, Alberto Borges, Laudelino Marques Lopes et Edward Araujo Júnior. « Clinical Diagnosis ». Dans Fetal Growth Restriction, 117–27. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-00051-6_8.

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Sullivan, Ashley, et Timothy Wang. « Clinical Diagnosis ». Dans Lentigo Maligna Melanoma, 15–25. Cham : Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-43787-3_3.

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Kim, Nancy, Sandra Y. Han et Siegrid S. Yu. « Clinical Diagnosis ». Dans Merkel Cell Carcinoma, 39–51. New York, NY : Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-6608-6_3.

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Jansson, Åsa. « Conclusion : Melancholia, Depression, and the Politics of Classification ». Dans From Melancholia to Depression, 209–28. Cham : Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-54802-5_7.

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Abstract The conclusion briefly highlights some alternative models of melancholia at the turn of the twentieth century, before turning the focus to the decline of the melancholia diagnosis and the rise of clinical depression as the new dominant mood disorder in diagnostic literature. The Conclusion considers how the developments outlined in the previous chapters have been foundational not only for the modern psychiatric concepts ‘mood disorder’ and ‘clinical depression’, but also more broadly for classification and clinical practice in twentieth- and twenty-first-century psychiatry. Finally, the book turns the spotlight to the politics of psychiatric classification, and asks what is at work, and at stake, when psychiatry tries to label, classify, and diagnose psychological distress.
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Gali, Raja Sekhar. « Reactive Lesions of Oro-Maxillofacial Region ». Dans Oral and Maxillofacial Surgery for the Clinician, 599–614. Singapore : Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_29.

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AbstractA plethora of pathologies occurs in the skeletal and soft tissues of the oro-facial region that are reactive. These arise as a result of chronic low-grade inflammation, trauma, hormonal influence and other causes. Varied types of clinical, radiological and histological presentations are often associated with these lesions that pose a diagnostic dilemma to the clinician. This chapter describes in detail the common reactive lesions of the maxillofacial region with an emphasis on correlating the clinical and investigational findings to arrive at the correct diagnosis and provide appropriate treatment.
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Actes de conférences sur le sujet "Diagnosi clinica"

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Rutledge, B., J. Vorro, L. DeStefano, T. Francisco, S. Gorbis et T. R. Bush. « Objective Measures Relating Cervical Dysfunction to Clinical Diagnosis and Treatment Effects ». Dans ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19612.

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The majority of musculoskeletal (MSD) impairments in the cervical (neck) region cannot be determined through MRIs or radiographs but are instead diagnosed through a clinical assessment technique using palpation. Palpatory diagnostic techniques are based on range of motion (ROM), tissue textures, quality of motion (smooth, elastic or bone on bone) and symmetry [1]. However, because scientifically accepted objective measures are not yet available to complement a clinical diagnosis, the documentation of the impairment as well as effects of treatment can be challenging. Thus, the purpose of this research was to explore the use of three-dimensional kinematics as a potential tool for relating movement patterns of the head/neck to clinical diagnosis and documenting treatment effects.
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Darie, Cristina, Diana Bulgaru Iliescu, Sorin Ungurianu et Anamaria Ciubara. « THE ONSET OF DEMENTIA THROUGH THE COTARD SYNDROME - THE DELIRIUM OF NEGATION ». Dans The European Conference of Psychiatry and Mental Health "Galatia". Archiv Euromedica, 2023. http://dx.doi.org/10.35630/2022/12/psy.ro.21.

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ICD-10 (The ICD-10 Classification of Mental and Behavioral Disorders. Clinical description and diagnostic guidelines) Introduction. Cotard syndrome is a neuropsychiatric pathology that is uncommon in medical practice but has a significant impact on public awareness of the importance of mental health. This mental disorder is also known as negation delirium, living dead syndrome, nihilistic delirium, or walking corpse syndrome. Objectives. A clinical case of a patient diagnosed with dementia due to late-onset Alzheimer's disease is presented; dementia also includes symptoms of Cotard's syndrome. Over time, the transmission of knowledge and data about Cotard Syndrome, despite its very low frequency, has become a pathology that intrigues and inspires curiosity among individuals. Consciousness of the existence of this delirious illness and the accurate definition of the symptoms of a dual diagnosis are required in a number of psychiatric pathologies. Method. This document was created using the "Elisabeta Doamna" psychiatry hospital Database from Galati, Romania, where patient data was acquired and admitted to the Psychiatry Clinic Section II. In addition, a variety of bibliographical references and diagnostic criteria were utilized, including the ICD-10 (the Classification of Mental and Behavioral Disorders, Clinical Description, and Diagnostic Guidelines), the DSM-5 (the Diagnostic and Statistical Manual of Mental Disorders), and the psychometric tests: the MMSE (the Mini Mental Status Test) and the GAFS (the Global Functioning Assessment Scale). Results and Conclusions Despite having no psychiatric history, the patient arrived at the psychiatric hospital after experiencing psychiatric symptoms caused by both Alzheimer's disease and Cotard's syndrome, symptoms that were ignored and gradually deteriorated, resulting in full-blown delirium, rapid dementia degradation, and a not-very-favorable outlook.
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Ramos, Júlia Xavier, Bruno Zacarias, Breno Barbosa et Simone Brandão. « 18-FDG PET ANALYSYS FOR DEMENTIA DIAGNOSIS- BASELINE RESULTS FROM A REFERENCE CENTER IN RECIFE, BRAZIL ». Dans XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda061.

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Background: Positrons emission tomography associated with computed tomography- PET/CT using the 18 F-fluorodeoxyglucose is a well-established exam for the medical evaluation of dementia, mainly helping in differential diagnosis to determine the specific type of dementia. Objectives: To describe the role of the PET/CT in the differential diagnosis of dementia in patients. Methods: a single-center, descriptive and records-based analysis of patients with Dementia evaluated in a clinic of Neurology at Recife and referred to PET/ CT due to diagnosis uncertainty, between 2020-2021. Results: 29 patients were included. The mean age was 65 years-old and 62% were female. Alzheimer’s dementia was the main diagnostic hypothesis (41.3%). PET/CT was suggestive of Alzheimer’s in 24%, Frontotemporal dementia in 21% and Lewy Bodies Dementia in 17% of patients. PET/CT results disagreed from clinical hypothesis in 21% o and in 10% it was inconclusive. In 38% it corroborated the clinical suspicion. Conclusions: in this sample the use of PET/CT FDG contributed to improve diagnostic accuracy in a significant subset of patients, mostly in the scenery of diagnostic uncertainty or atypical syndromes such as earlyonset dementias. A larger sample size and the continuation of this research will give us more information in the near future.
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Ribeiro, Fernanda Cristina Poscai, et Everton Lopes Rodrigues. « Differentiating clinical examinations of Parkinson’s and parkisonisms ». Dans XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.189.

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Introduction: The main symptoms of Parkinson are: tremors, movement resistance, postural instability and bradykinesia. However, other diseases such as Progressive Supranuclear Paralysis, Multiple System Atrophy and Corticobasal Degeneration have similar symptoms. This similarity generates a difficulty of diagnosis, for example, Corticobasal Degeneration is often diagnosed by autopsy. Objectives: To define the differentiating symptoms of Parkinson and the diseases mentioned and to find clinical tests that could aid in the diagnosis. Methodology: The integrative review utilized Scielo and Pubmed databases and the selected clinical examinations were obtained by the book Exame Clinico - 8° edition. Results: Multiple Systems Atrophy is distinguished from Parkinson by occurrence of cerebelar abnormalities, therefore Romberg Test can evidence modified coordination, which may be indicative of Multiple System Atrophy. Corticobasal Degeneration causes loss of ability to identify things by touch and impaired sensitivity on one side of the body, thereby the verification of stereognosia and the examination of superficial sensitivity are useful. Supranuclear Paralysis Progressive generates difficulty of performing vertical movements, thus the examination of ocular motility is necessary. Conclusion: Only clinical examinations aren’t sufficient to generate an accurate diagnosis and complementary exams are necessary for greater precision. However, knowledge about differentiating clinical examinations helps to generate a line of reasoning and examinations to be requested.
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Beri, Sonali, et Arun Khosla. « ASD Diagnoses using Deep Learning and Neuroimaging as A Biomarker : A Review ». Dans International Conference on Women Researchers in Electronics and Computing. AIJR Publisher, 2021. http://dx.doi.org/10.21467/proceedings.114.52.

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Autism Spectrum Disorder (ASD) is a commonly occurring neurodevelopmental disorder characterized by problems occurring in social communication and the presence of restricted and repetitive behavior and interests. Up to now, ASD is being diagnosed considering clinical interview, behavior and developmental factors. Early diagnosis of it can help the autistic people to deal well in their lives. For this early detection different biomarker like Neuro-imaging data can be used which includes structural and functional magnetic resonance imaging. In order to explore the functional and structural differences in between TC and autistic group deep learning methods can be used. These deep learning methods will help in efficient classification and thus can help in autism diagnosis as well. In this paper studies related to various Deep Learning techniques used to diagnose autism are being looked at.
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Albuquerque, Júlia Elizabeth Nagrad de Farias, Byanka Eduarda Silva de Arruda, Fernando de Paiva Melo Neto et Francisco Nêuton de Oliveira Magalhães. « Analysis of care in neurosurgery outpatient clinic in Paraíba ». Dans XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.277.

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Background: Currently the public health system encompasses numerous demands, including in the neurology and neurosurgery sector. The wide outpatient search shows several symptoms, with pain being one of the most prominent. Objectives: To analyze the consultations performed in a neurosurgery clinic, aiming to understand the main demands found at secondary health care. Design and setting: Retrospective and descriptive study, conducted through the analysis of data from a neurosurgery outpatient clinic in the state of Paraíba Methods: Conducted through the analysis of data from 73 patients relative to a neurosurgery outpatient clinic, during the period between 11/24/2020 and 12/15/2020. The variables were: gender, age and diagnostic suspicion. Results: A predominance of females was found (65.7%) and, among all patients, the youngest patient was 8 years old and the oldest was 83 years old. Among the patients, it was possible to observe an important presence of Headache (28.7%), followed by Back Pain (17.7%) and Psychiatric disorders (6.9%), the other patients presented several diagnoses, such as Cerebellar Syndrome (1.37%) and Neoplasms (5.5%). There was found male predominance in Sequelae of Stroke, Parkinson’s Disease, Spinal Pathologies, Autism, Brachial Plexus Injury, Carpal Tunnel Syndrome and Complex Painful Syndrome. Furthermore, it was noted equivalence of occurrence in both sexes of Neuropathic Pain, Convulsion, Post- Herpetic Neuralgia and Trigeminal Neuralgia. Conclusion: The search for regional standards and their comparison to the world scenario is important to assist in clinical diagnosis, besides helping in the allocation of resources and studies.
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Gahlot, Vibha, et Ranjit Kumar. « Nation wide urgent need for colposcopy services : Cancer hospital based study ». Dans 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685263.

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The cancer cervix is the second most common cancer among women worldwide. About 86% of the cases occur in developing countries and this is responsible for 88% of total deaths. In India 132,000 new cases are diagnosed each year with this disease and 74,000 deaths are recorded annually which accounts for the 1/3rd of the global deaths from cervical cancer. This hospital based study is designed to look at the distribution of the disease in patients coming to the Mahavir Cancer Sansthan with the aim to achieve an early diagnosis and treatment and recognition of disease in its preinvasive state for better outcome and quality of life. The patient registry data in Mahavir Cancer Sansthan showed that the total number of patients from all cancer were 20,746 in year 2013-2014. The cervical cancer constituted 14% of the patients. 50% of the patients belong to the six district of Bihar which falls in Gangetic plain. 700 case notes have been reviewed for clinical staging at the time of the diagnosis. 71% of the patients were in stage 2b at the time of first clinical presentation, 24% in stage 3% and 4% were in stage 4. Only 1% patients were found in stage1. The colposcopy clinic data suggest only 0.04% patients have approached to us at preinvasive stage. We conclude from this study that although this hospital is mainly a referral cancer hospital 99% patient have reported to the hospital at stage 2b and beyond. Given the natural History of cervical cancer this is only the tip of iceberg. A robust system for colposcopy services needed to diagnose this disease at its preinvasive and micro invasive stage to reduce the morbidity and mortality and improvement in the quality of the life of the patients.
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Freijanes, Loise Maria de Souza, Elisa Yuki Kurosawa Ueda, Paola Restum Antonio Lemaitre et Isabela Pierotti Prado. « Cerebral Aspergillosis : Literature Review ». Dans XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.161.

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Background: Cerebral Aspergillosis is an opportunistic fungal infection. It reaches by a hematogenous pathway or by paranasal sinuses. Furthermore, the diagnosis is delayed due to the nonspecific clinical signs. Objectives: This study aims to highlight cerebral invasive aspergillosis as a diagnostic hypothesis in a difficult-to-diagnose and nonspecific neurological clinical scenario. Design and setting: This is a literature review from the Escola de Medicina Souza Marques‘s students, Brazil. Methods: The used articles were published between 2016 to 2021, from UpToDate, Journal of Oncology Pharmacy Practice, Elsevier, and Google Academic databases. Results: In immunosuppressed individuals, it manifests as single or multiple brain abscesses with vascular invasion, posing as a life-threatening factor. Immunocompetent patients may respond differently, presenting with meningitis or granulomatous mass, associated with seizures, headache, and visual acuity impairment. MRI or PCR in cerebrospinal fluid is the most used for diagnosis. T2 hypodensity, irregular margins with intracavitary projections on MRI, and absence of the choline peak suggest a fungal etiology. The histopathological study is not common in clinical practice. The recommended treatment is voriconazole in association with echinocandins, for 6 to 12 weeks. Notably, the mortality rate of cerebral aspergillosis in patients who are taking Ibrutinib for other conditions is close to 90%. Conclusion: Therefore it is essential to recognize the complication to avoid morbidity and mortality in immunosuppressed and immunocompetent individuals.
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Krahenbuhl, B., E. Sheybani et H. Bounameaux. « ASSESSMENT OF DIAGNOSIS OF DEEP VENOUS THROMBOSIS OF THE LOWER LIMBS USING ESTIMATION OF CLINICAL PROBABILITY ». Dans XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644196.

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The value of a diagnostic test (or test combination) depends not only on its sensitivity and specificity but also on the prevalence of the disease. In the present study, we have re-assessed the value of the clinical diagnosis in a group of 45 consecutive patients suspected of deep venous thrombosis (DVT) of the lower limbs. The clinical probability (CP) of the diagnosis was estimated on a clinical basis alone (history and clinical examination) by trained physicians (2-month training in an Angiology Unit). Afterwards, the diagnosis of DVT was established using the combination of Doppler ultrasounds and venous occlusive plethysmography. Venography was performed when the non invasive techniques were inconclusive.DVT was found in 14 patients (31 %). In the 21 patients in whom CP was ⩽ 0.20, there was no DVT. In the 10 patients in whom CP was ⩾ 0.80, DVT was confirmed in 9 cases. When CP was between 0.21 and 0.79, a DVT was found in 5 out of 14 patients.Thus, when CP is ⩾ 0.80 or ⩽ 0.20, further investigation does not seem to provide additional diagnostic information. The estimation of CP by a trained physician allows to define a subgroup of patients in whom the clinical diagnosis is valuable.Two third of the patients in our series belong to this subgroup. In one third of the patients, CP was intermediate and non invasive tests or venography are necessary.Since the range of clinical probability in which clinical diagnosis is reliable will depend on both the physician and the recruitment of the patients (medical or surgical, ambulatory or hospitalized), it must be determined in each center.
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Senna, Priscylla de, Wyllians Borelli, Wagner Brum, Eduardo Zimmer, Márcia Chaves, Arthur Schuh et Raphael Castilhos. « FUNCTIONAL COGNITIVE DISORDER AS THE MOST FREQUENT DIAGNOSIS IN PUBLIC MEMORY CLINIC ». Dans XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda059.

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Background: Functional cognitive disorder (FCD) has been described as a blind spot of dementia care. Objectives: Identify the frequency of FCD in a tertiary memory clinic (TMC). Methods: A retrospective analysis was conducted to identify new referrals from the primary care setting to a TMC from southern Brazil over 2014 to 2020. Diagnostic protocol included neurologic evaluation, cognitive screening, neuroimaging and laboratory testing. FCD was defined as cognitive complaints without objective cognitive decline, in the absence of evidence of neurodegenerative disease. Data is shown in mean (SD). Results: 516 patients (61% females, mean age 70.76±10.3 years) with a mean of 4.5 (+-3.94) years of education were referred. The diagnoses were: FCD (146, 28.3%); Alzheimer’s dementia (115, 22.3%); Mild Cognitive Impairment (51, 9.9%), vascular dementia (36, 7%); other types, including less common causes of dementia and rare pathologies (168, 7.6%). FCD patients were younger (66.2 (±9.4) vs. 72.6, p <0.001), and showed higher Geriatric Depression Scale than non-FCD patients (7.4 (±4.5) vs. 5.3 (±3.7), p <0.001). Education level did not differ. Conclusions: FCD was the most frequent diagnosis. Primary care strategies may greatly improve early diagnosis and treatment to these patients.
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Rapports d'organisations sur le sujet "Diagnosi clinica"

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Sun, Lina, Yanan Han, Hua Wang, Huanyu Liu, Shan Liu, Hongbin Yang, Xiaoxia Ren et Ying Fang. MicroRNAs as Potential Biomarkers for the Diagnosis of Inflammatory Bowel Disease : A Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, février 2022. http://dx.doi.org/10.37766/inplasy2022.2.0027.

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Review question / Objective: The purpose of this systematic review was to systematically review the clinical studies regarding miRNAs as diagnostic biomarkers for inflammatory bowel disease and assess the overall diagnostic accuracy of miRNAs. Condition being studied: The symptoms of inflammatory bowel disease (IBD) are highly variable. The diagnosis of IBD must be made through medical history, physical, laboratory, radiologic, endoscopic, and histological examinations. However, these diagnostic techniques are not specific and sometimes even equivocal. Therefore, reliable biomarkers are urgently needed in the diagnosis of IBD. Several clinical and preclinical researches have shown that dysregulated microRNAs (miRNAs) play a crucial role in IBD development. miRNAs, as single-stranded noncoding RNAs that contain 22-24 nucleotides, can post-transcriptionally regulate gene expression by blocking mRNA translation or degrading target mRNAs. miRNAs are widely involved in physiological and pathological cellular processes, such as differentiation, proliferation and apoptosis. Besides, they are stable, noninvasive, and resistant to degradation by ribonucleases, making them valuable targets in the diagnosis, monitoring, prognosis, and treatment of diseases. To date, inconsistent results have been found about miRNA expression profiling in the patients with IBD. Moreover, the diagnostic accuracy of miRNAs for IBD has not been reported in any meta-analysis.
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WANG, MIN, Sheng Chen, Changqing Zhong, Tao Zhang, Yongxing Xu, Hongyuan Guo, Xiaoying Wang, Shuai Zhang, Yan Chen et Lianyong Li. Diagnosis using artificial intelligence based on the endocytoscopic observation of the gastrointestinal tumours : a systematic review and meta-analysis. InPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, février 2023. http://dx.doi.org/10.37766/inplasy2023.2.0096.

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Review question / Objective: With the development of endoscopic techniques, several diagnostic endoscopy methods are available for the diagnosis of malignant lesions, including magnified pigmented endoscopy and narrow band imaging (NBI).The main goal of endoscopy is to achieve the real-time diagnostic evaluation of the tissue, allowing an accurate assessment comparable to histopathological diagnosis based on structural and cellular heterogeneity to significantly improve the diagnostic rate for cancerous tissues. Endocytoscopy (ECS) is based on ultrahigh magnification endoscopy and has been applied to endoscopy to achieve microscopic observation of gastrointestinal (GI) cells through tissue staining, thus allowing the differentiation of cancerous and noncancerous tissues in real time.To date, ECS observation has been applied to the diagnosis of oesophageal, gastric and colorectal tumours and has shown high sensitivity and specificity.Despite the highly accurate diagnostic capability of this method, the interpretation of the results is highly dependent on the operator's skill level, and it is difficult to train all endoscopists to master all methods quickly. Artificial intelligence (AI)-assisted diagnostic systems have been widely recognized for their high sensitivity and specificity in the diagnosis of GI tumours under general endoscopy. Few studies have explored on ECS for endoscopic tumour identification, and even fewer have explored ECS-based AI in the endoscopic identification of GI tumours, all of which have reached different conclusions. Therefore, we aimed to investigate the value of ECS-based AI in detecting GI tumour to provide evidence for its clinical application.
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López-Valverde, Nansi, Antonio López-Valverde, Ana Suarez, Bruno Macedo de Sousa et Juan Manuel Aragoneses. Association of gastric infection and periodontal disease through Helicobacter pylori as a common denominator : A systematic review and meta-analysi. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, octobre 2021. http://dx.doi.org/10.37766/inplasy2021.10.0097.

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Review question / Objective: Is gastric helicobacter pylori infection related to periodontal diseases? Condition being studied: Therefore, the aim of this systematic review and meta-analysis was to identify and analyze clinical studies to determine the direct correlation between Helicobacter Pylori gastric infection andPeriodontal Disease. Study designs to be included: Clinical studies that provided data on Helicobacter Pylori infection in both the stomach and oral cavity, confirmed by polymerase chain reaction (PCR), rapid urease test (RUT) or enzyme-linked immunosorbent assay (ELISA). Clinical studies that associated PD with Helicobacter Pylori. The diagnosis of PD was confirmed ac-cording to the diagnostic criteria in periodontology.
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Fink, Howard A., Laura S. Hemmy, Eric J. Linskens, Pombie C. Silverman, Roderick MacDonald, J. Riley McCarten, Kristine M. C. Talley et al. Diagnosis and Treatment of Clinical Alzheimer's-Type Dementia. Agency for Healthcare Research and Quality (AHRQ), avril 2020. http://dx.doi.org/10.23970/ahrqepccer223.

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Zhang, Chen qi, kexin Zheng, Lingqi Sun et Hongbin Sun. Effects of magnesium valproate adjuvant therapy on patients with dementia : A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, novembre 2021. http://dx.doi.org/10.37766/inplasy2021.11.0038.

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Review question / Objective: To evaluate the efficacy of magnesium valproate(VPM) in the adjuvant treatment of patients with dementia(PwD). Participant or population: Adults with dementia (as diagnosed by a clinician, or using any recognized diagnostic criteria) will be included. Information sources: MEDLINE via PubMed, Cochrane Library, EBSCO, Embase, China National Knowledge(CNKI) and Wan fang databases.
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Weng, JIeqiong, Jingfang Zhang, Ke Xu, Mengfei Yuan, Tingting Yao, Xinyu Wang et Xiaoxu Shen. Efficacy of Shexiang Baoxin Pills Combined with Statins on Blood Lipid Profile in Patients with Coronary Heart Disease : A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, septembre 2022. http://dx.doi.org/10.37766/inplasy2022.9.0100.

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Review question / Objective: P（Population) ：Patients with coronary heart disease; I（Intervention) : Statins treatment in combination with Shexiang Baoxin pill; C（Comparison): Statins alone; O（Outcome）: Improvement of symptoms and blood lipids; S（Study design）：Clinical randomized trials. Eligibility criteria: To be included, trials were required to meet the following criteria: (1) patients were included in the studies according to diagnostic criteria of coronary heart disease established by the WHO, InternationalSociety of Cardiology and Association (ISCA), Internal Medicine, 7th edition ( IM-7th), Practice of InternalMedicine, 14th edition ( PIM-14th), Guidelines for the Diagnosis of Cardiovascular Diseases in InternalMedicine, 3rd edition (GIM-3rd) or conventional diagnostic criteria (CDC) including assessment of anginapectoris and electrocardiogram (ECG) results; (2) the study was conducted as a randomized controlled trial.
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Kilbourne, B., J. Goodman et S. Hilton. Some Clinical Diagnoses are More Reliable than Others. Fort Belvoir, VA : Defense Technical Information Center, mars 1989. http://dx.doi.org/10.21236/ada211079.

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Mahmoudi, Farhad, Mahtab Mokarram, Sadegh Sabouhi, Sara Hashemi, Parastoo Saberi et Hadi Zamanian. Application of digital health for improving medication adherence in MS patients. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, octobre 2021. http://dx.doi.org/10.37766/inplasy2021.10.0058.

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Review question / Objective: The aim of this study is to evaluate the efficacy of digital health interventions in monitoring and improving medication adherence in Multiple Sclerosis patients. Condition being studied: Multiple sclerosis (MS) is the most prevalent chronic inflammatory disease of the central nervous system (CNS), which leads to focal lesions in the white matter, characterized by selective primary demyelination with partial preservation of axons and reactive astrocytic gliosis. The disease is thought to be due to a complex interaction between different genetic and environmental factors. The prevalence of MS is rising all over the world, due on one hand to earlier diagnosis and prolonged survival, and on the other to a true increase in incidence of the disease. The diagnosis of MS remains clinical despite recent advances in diagnostics and relies on demonstrating dissemination in space and time while excluding alternative diagnoses.
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Zhuravleva, M. O. DIFFICULTIES IN THE DIAGNOSIS OF REACTIVE ARTHRITIS DOCTORS EMULATORE-OUTPATIENT CLINICS. Планета, 2018. http://dx.doi.org/10.18411/978-5-907109-24-7-2018-xxxiv-64-69.

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Qin, Ling, Qiyu Liu, Hui Wang et Lipeng Sun. Accuracy of ultrasound in distinguishing pathology of malignant thyroid diseases : A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, décembre 2021. http://dx.doi.org/10.37766/inplasy2021.12.0072.

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Review question / Objective: This meta-analysis aimed to determine the accuracy of ultrasound in distinguishing pathology of malignant thyroid diseases. Eligibility criteria: Type of study. This study will only include high quality clinical cohort or case control studies. Type of patients. The patients should be those who had undergone breast diseases. Intervention and comparison. This study compares AI with pathology for diagnosing breast diseases. Type of outcomes. The primary outcomes include sensitivity, specificity, positive and negative likelihood ratio, diagnostic odds ratio, and the area under the curve of the summary receiver operating characteristic.
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