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1

Ramonaitė, Justė, Gabija Imbrasaitė, Alfredas Smailys, Mindaugas Stravinskas, and Vėtra Markevičiūtė. "THE NEED FOR MULTIPLE SURGERIES FOR FREQUENT DESMOID TUMOR RECURRENCE." Health Sciences 33, no. 5 (2023): 39–43. http://dx.doi.org/10.35988/sm-hs.2023.176.

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Desmoid tumors are very rare mesenchymal neoplasms with an estimated incidence of 3 per 100 soft tissue tumor cases. They are locally invasive, aggressive and cause significant complications. The treatment modalities of desmoids include surgery, radiotherapy, chemotherapy, hormonal therapy. Currently there is no gold standard and neither therapy is effective for high recurrence (25‑77%) desmoid tumors. Desmoid tumors also have the capacity for self-limitation and, therefore, no treatment other than observation is possible expecting spontaneous regression. Treatment options for desmoid tumors a
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Khandelwal, Niranjan, Mandeep Garg, Nidhi Prabhakar, and Divya Dahiya. "Desmoid Tumor: Rare Abdominal Wall Lump in a Multiparous Woman." Journal of Postgraduate Medicine, Education and Research 52, no. 1 (2018): 31–33. http://dx.doi.org/10.5005/jp-journals-10028-1271.

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ABSTRACT Background Desmoids are rare tumors. Abdominal wall desmoids are more common in women of reproductive age, especially postpartum women. Here we present a case of desmoid tumor in a 37-year-old multiparous woman, who came with the complaint of a slowly growing painless abdominal lump. Case report A 37-year-old multiparous female presented with the complaint of a gradually increasing, painless abdominal lump. On physical examination, a well-defined, firm, mobile mass was palpated in the suprapubic region. Ultrasound revealed a homogeneous hypoechoic lesion in the right anterolateral abd
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Koshariya, Mahim, Samir Shukla, Zuber Khan, et al. "Giant Desmoid Tumor of the Anterior Abdominal Wall in a Young Female: A Case Report." Case Reports in Surgery 2013 (2013): 1–4. http://dx.doi.org/10.1155/2013/780862.

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Desmoid tumors (also called desmoids fibromatosis) are rare slow growing benign and musculoaponeurotic tumors. Although these tumors have a propensity to invade surrounding tissues, they are not malignant. These tumors are associated with women of fertile age, especially during and after pregnancy. We report a young female patient with a giant desmoid tumor of the anterior abdominal wall who underwent primary resection. The patient had no history of an earlier abdominal surgery. Preoperative evaluation included abdominal ultrasound, computed tomography, and magnetic resonance imaging. The hist
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MINAMI, YUSUKE, SEIICHI MATSUMOTO, KEISUKE AE, et al. "The Clinical Features of Multicentric Extra-abdominal Desmoid Tumors." Cancer Diagnosis & Prognosis 1, no. 4 (2021): 339–43. http://dx.doi.org/10.21873/cdp.10045.

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Background: Extra-abdominal desmoid tumors often occur in the necks, shoulder, chest wall, back, arm, buttock, thigh and leg. Multicentric extra-abdominal desmoids are rather rare and seem to have other clinical features. The aim of our study was to investigate clinical features, especially multicentric occurrence of extra-abdominal desmoid tumors. Patients and Methods: A total of 135 patients diagnosed with extra-abdominal desmoid were enrolled in this study from January 2005 to December 2019 at the Cancer Institute Hospital of The Japanese Foundation for Cancer Research. The operative proced
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Salas, Sébastien, Armelle Dufresne, Binh Bui, et al. "Prognostic Factors Influencing Progression-Free Survival Determined From a Series of Sporadic Desmoid Tumors: A Wait-and-See Policy According to Tumor Presentation." Journal of Clinical Oncology 29, no. 26 (2011): 3553–58. http://dx.doi.org/10.1200/jco.2010.33.5489.

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Purpose Desmoid tumors are mesenchymal fibroblastic/myofibroblastic proliferations with locoregional aggressiveness and high ability to recur after initial treatment. We present the results of the largest series of sporadic desmoid tumors ever published to determine the prognostic factors of these rare tumors. Patients and Methods Four hundred twenty-six patients with a desmoid tumor at diagnosis were included, and the following parameters were studied: age, sex, delay between first symptoms and diagnosis, tumor size, tumor site, previous history of surgery or trauma in the area of the primary
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Leal, Raquel Franco, Patricia V. V. Tapia Silva, Maria de Lourdes Setsuko Ayrizono, João José Fagundes, Eliane M. Ingrid Amstalden, and Cláudio Saddy Rodrigues Coy. "Desmoid tumor in patients with familial adenomatous polyposis." Arquivos de Gastroenterologia 47, no. 4 (2010): 373–78. http://dx.doi.org/10.1590/s0004-28032010000400010.

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CONTEXT: Desmoid tumors constitute one of the most important extraintestinal manifestations of familial adenomatous polyposis. The development of desmoids is responsible for increasing morbidity and mortality rates in cases of familial adenomatous polyposis. OBJECTIVES: To evaluate the occurrence of desmoid tumors in familial adenomatous polyposis cases following prophylactic colectomy and to present patient outcome. METHODS: Between 1984 and 2008, 68 patients underwent colectomy for familial adenomatous polyposis at the School of Medical Sciences Teaching Hospital, University of Campinas, SP,
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Makarenko, M. V., D. O. Govseyev, S. V. Gridchin, et al. "Desmoid tumor of the anterior abdominal wall in a female (Clinical case)." HEALTH OF WOMAN, no. 5(131) (June 30, 2018): 116–18. http://dx.doi.org/10.15574/hw.2018.131.116.

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Desmoid tumors (also called desmoids fibromatosis) are rare slow growing benign and musculoaponeurotic tumors. Although these tumors have a propensity to invade surrounding tissues, they are not malignant. These tumors are associated with women of fertile age, especially during and after pregnancy and postoperative surgeries. Our clinical case is interesting because of the rarity of the pathology and the difficulties in setting the correct diagnosis. The patient, with a history of laparoscopic myomectomy (2012), was preparing for a routine surgery for the endometrioma of the anterior abdominal
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Boceska, Zhaneta P., Katerina B. Kubelka-Sabit, and Julija Zh Zhivadinovik. "FIBROMATOSIS (DESMOID TUMOR) OF THE BREAST. Fibromatosis (tumor desmoide) de mama." Revista Argentina de Anatomía Clínica 3, no. 2 (2016): 99–105. http://dx.doi.org/10.31051/1852.8023.v3.n2.13926.

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El tumor desmoide (fibromatosis) es una entidad patológica extremadamente rara que se desarrolla de la fascia muscular y la aponeusorsis. Aunque sin potencial metastático, estos tumores son localmente muy agresivos y tienden a infiltrarse en los tejidos circundantes. Nosotros presentamos un caso de tumour desmoide de mama, que tuvo apariencias clínicas sugestivas a carcinoma. La paciente, de 56 años presentó una masa palpable de mama derecho. La citología por aspiracion con aguja fina (AGF) no detectó ninguna célula maligna, por lo que se hizo una escisión local conservadora. La paciente no re
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Murshid, Areen Abdulelah, and Hatim Q. Al-Maghraby. "Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor." Case Reports in Pathology 2018 (2018): 1–5. http://dx.doi.org/10.1155/2018/1082956.

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Desmoid tumors (deep fibromatosis) of the mesentery are rare mesenchymal tumors. They are often misdiagnosed, especially with a previous history of resection for gastrointestinal stromal tumor (GIST). Immunohistochemistry can help differentiate between these two tumors. In this article, we present a case we had encountered: a Desmoid tumor developing in a patient with a history of GIST 3 years ago. It is the first case of GIST with subsequent development of Desmoid tumor to be reported in Saudi Arabia. We discuss the two entities of Desmoid tumor and GIST by comparing their definitions, clinic
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Mercier, Kelly A., and Darragh M. Walsh. "The initiation, design, and establishment of the Desmoid Tumor Research Foundation Patient Registry and Natural History Study." Rare Tumors 11 (January 2019): 203636131988097. http://dx.doi.org/10.1177/2036361319880978.

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Desmoid tumors are locally invasive sarcoma, affecting 5–6 individuals out of 1,000,000 per year. The desmoid tumors have high rates of recurrence after resection and can lead to significant deterioration of the quality of life of patients. There is a need for a better understanding of the desmoid tumors’ patient experience from first symptoms through diagnosis, disease monitoring, and clinical treatment options. With the National Organization of Rare Disorders, the Desmoid Tumor Research Foundation Natural History Study was designed to be collected through the registry. This article describes
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Singh, Neeraj, Rohit Sharma, Sanford A. Dorman, and Victor C. Dy. "An Unusual Presentation of Desmoid Tumor in the Ileum." American Surgeon 72, no. 9 (2006): 821–24. http://dx.doi.org/10.1177/000313480607200911.

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Desmoid tumors are nonencapsulated, locally invasive tumors of fibrous origin. Although lacking the ability to metastasize, they are notorious for recurrence. A wide variety of locations have been documented in the literature with respect to the origin of these tumors. Intra-abdominal desmoids are commonly found in the mesentery. We present the report of a case in which a sporadic desmoid tumor originated from the wall of the ileum. The patient was successfully treated with surgery alone, and has remained recurrence free on follow-up. Modalities of treatment documented in the literature includ
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Ataizi, Zeki Serdar, Gulay Simsek, Fulya Colak Ataizi, and Serdar Ercan. "Does A Vertebra Fracture Cause A Tumor? A Dorsolumbar Paraspinal Desmoid Tumor: Case Report." Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery 39, no. 01 (2020): 058–60. http://dx.doi.org/10.1055/s-0039-3399538.

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AbstractExtraabdominal desmoid tumors are uncommon soft-tissue tumors. The etiology of the tumor is still unclear. Injury is one of the etiological factors of soft-tissue tumors. A 41-year-old female patient who had a traumatic vertebral body fracture on the thoracic spine was treated conservatively. Two and a half years later, she presented a painful, palpable swelling on the thoracolumbar region. In the present report, was discuss the patient, who underwent a surgery to remove the desmoid tumor (aggressive fibromatosis), within the context of the current literature. The literature on desmoid
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Li, Luyuan, John N. Jensen, Sara Szabo, Peter VanTuinen, and Sean M. Lew. "Recurrent giant cranial desmoid tumor in a 3-year-old boy with familial adenomatous polyposis requiring bifrontoparietal cranioplasty: case report." Journal of Neurosurgery: Pediatrics 18, no. 6 (2016): 703–7. http://dx.doi.org/10.3171/2016.6.peds15741.

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Desmoid tumors, also known as aggressive fibromatosis, are locally infiltrating musculoaponeurotic neoplasms arising in connective tissues. Desmoid tumors may be associated with familial adenomatous polyposis (FAP), a genetic disorder that presents with hundreds to thousands of precancerous colorectal polyps. The authors report the case of an 18-month-old boy who underwent resection of a right temporal desmoid tumor (initially diagnosed as cranial fasciitis) and developed a bilateral frontoparietal calvarial desmoid tumor 2 years later. The patient underwent gross-total resection of the tumor
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Lev, Dina, Dhanasekaran Kotilingam, Caimiao Wei, et al. "Optimizing Treatment of Desmoid Tumors." Journal of Clinical Oncology 25, no. 13 (2007): 1785–91. http://dx.doi.org/10.1200/jco.2006.10.5015.

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Purpose This study compared a large series of desmoid patients treated at a single institution to a previously published series from the same institution to determine if patient population characteristics, treatment approaches, and clinical outcomes had undergone change over the two study periods. Materials and Methods Data from a prospective soft tissue tumor database was used to analyze clinical courses of 189 desmoid patients treated at The University of Texas M.D. Anderson Cancer Center (UTMDACC) from 1995 to 2005 as compared with 189 UTMDACC desmoid patients treated between 1965 and 1994.
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Nath, Meryl C., Michael S. Torbenson, and Lori A. Erickson. "Desmoid Tumor." Mayo Clinic Proceedings 93, no. 4 (2018): 549–50. http://dx.doi.org/10.1016/j.mayocp.2018.02.009.

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Berri, Richard N., Donald P. Baumann, John E. Madewell, Alexander Lazar, and Raphael E. Pollock. "Desmoid Tumor." Annals of Plastic Surgery 67, no. 5 (2011): 551–64. http://dx.doi.org/10.1097/sap.0b013e3182084cf6.

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&NA;. "Desmoid tumor." Advances in Anatomic Pathology 5, no. 3 (1998): 184. http://dx.doi.org/10.1097/00125480-199805000-00021.

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Chan, David, Jason Kaplan, Gary Gordon, and Jayesh Desai. "Activity of the Gamma Secretase Inhibitor AL101 in Desmoid Tumors: A Case Report of 2 Adult Cases." Current Oncology 28, no. 5 (2021): 3659–67. http://dx.doi.org/10.3390/curroncol28050312.

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Desmoid tumors (aggressive fibromatosis) are soft tissue mesenchymal tumors that can be locally invasive and life-threatening. Depending on the location, these tumors are often unresectable or tend to recur after surgery. To date, there are no approved systemic therapies for desmoid tumors. These tumors typically harbor mutations in the β-catenin oncogene CTNNB1 or the tumor suppressor gene adenomatous polyposis coli, resulting in constitutive activation of the WNT pathway. The Notch pathway is part of the underlying cause for desmoid tumor development, possibly due to crosstalk with the WNT p
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Makhson, A. N., N. E. Makhson, and M. Y. Shupak. "Desmoplastic fibroma (desmoid) of the femur: 2 cases." N.N. Priorov Journal of Traumatology and Orthopedics 6, no. 4 (1999): 66–68. http://dx.doi.org/10.17816/vto105618.

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Desmoplastic fibroma (extra-abdominal desmoid) was first identified as an independent nosological form in 1958 by H.L. Jaffe [6]. This tumor differs significantly in its course from the desmoid of the abdominal wall. It has a pronounced ability to infiltrate the surrounding tissues, there are frequent cases of tumor spread to the vessels and nerves. The disease usually affects soft tissues. Extra-abdominal desmoids often occur in the area of ​​the shoulder, chest wall, back, and scapula [1, 6]. Desmoplastic bone fibromas are extremely rare. So, R. Buhm et al. [5] described two cases of this tu
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Oybek, Davronov, Gippeum Park, Uralboev Ikromjon Erkinovich, and Hwunjae Lee. "A Case Study of Abdominal Wall Desmoid Tumor in a 33-Year-Old Woman." Journal of Medical Imaging 7, no. 1 (2024): 1–5. https://doi.org/10.31916/sjmi2024-01-01.

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Desmoid tumors, also known as aggressive fibromatosis, are rare, benign soft tissue neoplasms characterized by locally invasive growth. These tumors originate from fibroblasts and commonly occur in the abdominal wall, particularly in females of reproductive age. Although desmoid tumors are non-metastatic, they can infiltrate surrounding tissues, leading to significant morbidity and a high recurrence rate following incomplete surgical excision. The exact etiology of desmoid tumors remains unclear; however, genetic mutations, hormonal influences, and trauma are considered contributing factors. I
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Křístek, Jan, Dagmar Adámková Krákorová, Karel Veselý, et al. "Desmoid tumor/aggressive fibromatosis." Česká radiologie 78, no. 3 (2024): 158–63. https://doi.org/10.55095/cesradiol2024/022.

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Mizuno, Mari, Yoshiaki Kawaguchi, Aya Kawanishi, et al. "An Intra-Abdominal Desmoid Tumor, Embedded in the Pancreas, Preoperatively Diagnosed as an Extragastric Growing Gastrointestinal Stromal Tumor." Case Reports in Oncology 10, no. 1 (2017): 301–7. http://dx.doi.org/10.1159/000468983.

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A 45-year-old woman was found to have a pancreatic tumor by abdominal ultrasound performed for a medical check-up. Abdominal contrast-enhanced computed tomography showed a hypovascular tumor measuring 30 mm in diameter in the pancreatic tail. Endoscopic ultrasound-guided fine needle aspiration was performed. An extragastric growing gastrointestinal stromal tumor was thereby diagnosed preoperatively, and surgical resection was planned. Laparoscopic surgery was attempted but conversion to open surgery was necessitated by extensive adhesions, and distal pancreatectomy, splenectomy, and partial ga
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Margarint, Irina Maria, Tammam Youssef, Cristina Filip, et al. "A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report." Life 15, no. 1 (2025): 123. https://doi.org/10.3390/life15010123.

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Desmoid tumors are a rare entity, especially in the pediatric population. There are no reports of such a tumor in newborns. They are associated with high rates of morbidity and mortality, even though they are benign soft tissue tumors. This is due to them exhibiting locally aggressive growth with the compression or invasion of adjacent structures. Abdominal localization is most commonly reported, although there are reports of mediastinal desmoid tumors. We present the case of a 6-day male patient with a mediastinal desmoid tumor that led to severe aortic coarctation with hemodynamic instabilit
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Majors, Jaqueline, Nathaniel F. Stoikes, Reza Nejati, and Jeremiah L. Deneve. "Resection and Abdominal Wall Reconstruction of a Desmoid Tumor with Endometrioma Features." Case Reports in Surgery 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/9453450.

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Desmoid tumors are rare, musculoaponeurotic mesenchymal origin tumors arising from the proliferation of well-differentiated fibroblasts. Desmoid tumors may arise from any location with the abdominal cavity, abdominal wall and extremity locations being most frequent. We present the case of a 35-year-old female with a history of endometriosis who presented palpable abdominal mass and cyclic abdominal pain. Resection was performed for a presumed desmoid soft tissue tumor. Final pathology demonstrated desmoid histology admixed with abdominal wall endometriosis (endometrioma). This unique pathologi
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Zenzri, Yosr, Yosra Yahyaoui, Lamia Charfi, et al. "The Management of Desmoid Tumors: A Retrospective Study of 30 Cases." International Journal of Surgical Oncology 2020 (July 18, 2020): 1–7. http://dx.doi.org/10.1155/2020/9197216.

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Objectives. Desmoid tumor also called aggressive fibromatosis is a rare type of benign tumor. It is a mesenchymal malignancy without metastatic potential. The standard management is resection, but other options including observation may be discussed. Desmoid-type fibromatosis may occur throughout the body, but the abdominal wall is the most common site. The aim of our study was to assess the clinicoepidemiological profile, prognostic factors, and treatment outcome of desmoid tumors. Methods. A monocentric retrospective study was conducted over a period of 19 years between February 2000 and Nov
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Hapgood, Connie, and Allison DeLong. "Recurrent Enlarging Mesenteric Desmoid Tumor following Remote Surgical Resection." Case Reports in Radiology 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/2312617.

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Intra-abdominal desmoid tumors are commonly associated with genetic syndromes such as familial polyposis coli. Radiological cross imaging studies such as CT and MRI are used in the preoperative work-up of such tumors. Postoperatively, CT and MRI are useful in the assessment of recurrent desmoid tumors. MRI is more accurate in tissue characterization. Where possible, surgical resection remains the standard first-line treatment. For patients where surgery is not possible, or the resection margins are not clear, other forms of treatment are possible. These include hormonal and nonhormonal options
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Santos, Daniel Britto, Jomar Rezende, Arthur Mendes Gasperini, et al. "Tumor Desmóide: Relato de Caso / Desmoid Tumor: A Case Report." Brazilian Journal of Development 7, no. 11 (2021): 101782–92. http://dx.doi.org/10.34117/bjdv7n11-005.

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M. Al-Rekabi, Adel. "Desmoid tumors of the abdominal wall:Two cases report." AL-QADISIYAH MEDICAL JOURNAL 4, no. 6 (2017): 151–55. http://dx.doi.org/10.28922/qmj.2008.4.6.151-155.

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Desmoid tumors are slow growing deep fibromatoses with aggressive infiltration of adjacent tissue but without any metastatic potential.We report on two female patients with desmoid tumor of the abdominal wall who underwent primary resection and proline mesh repair. Bothpatients had a history of an earlier abdominal surgery. Preoperative evaluation included abdominal ultrasound,and computed tomography. The histology in both cases revealed a desmoid tumor.Complete surgical resection and proline mesh repair is the first line management of this tumor entity.
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Smith, Steven Christopher, Kieran Sweeney, Andrew Elliott, et al. "Gamma secretase inhibitors and desmoid fibromatosis: Lessons from a real world, comprehensive genomic study of desmoids and CTNNB1 / APC mutated soft tissue tumors." Journal of Clinical Oncology 43, no. 16_suppl (2025): 11547. https://doi.org/10.1200/jco.2025.43.16_suppl.11547.

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11547 Background: Recently, first-in-class FDA approval was granted in the U.S. for use of the gamma secretase inhibitor (GSI), nirogacestat, for adults with progressive desmoid fibromatosis. In tandem, the unpredictable clinical behavior of desmoids, which ranges from local aggression to regression, raises consideration of whether diagnostic and molecular variability underlie their varying biological potential. With an aim to understand both, and to explore the potential for biomarkers for GSI therapy selection, prediction, and prognosis, we performed a retrospective review of comprehensive g
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Nathenson, Michael J., Junxiao Hu, Ravin Ratan, et al. "Systemic Chemotherapies Retain Antitumor Activity in Desmoid Tumors Independent of Specific Mutations in CTNNB1 or APC: A Multi-institutional Retrospective Study." Clinical Cancer Research 28, no. 18 (2022): 4092–104. http://dx.doi.org/10.1158/1078-0432.ccr-21-4504.

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Abstract Purpose: Determine whether specific CTNNB1 or APC mutations in patients with desmoid tumor were associated with differences in clinical responses to systemic treatments. Experimental Design: We established a multi-institutional dataset of previously treated patients with desmoid tumor across four U.S. sarcoma centers, including demographic and clinicopathologic characteristics, treatment regimens, and clinical and radiographic responses. CTNNB1 or APC mutation status was determined from prior pathology records, or archival tissue was requested and analyzed by Sanger sequencing and/or
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Liu, Seiya, Bernadette Miramontes, Felipe Ferreira Souza, et al. "Cryoablation as an effective treatment for desmoid tumors: A single-institution case series." Journal of Clinical Oncology 40, no. 16_suppl (2022): e23543-e23543. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e23543.

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e23543 Background: Desmoid tumors are locally invasive mesenchymal neoplasms of fibroblastic origin arising in deep soft tissue. Despite a rare incidence of 2.4-4.3 per one million and an inability to metastasize, desmoid tumors can cause significant morbidity by invading surrounding structures, causing pain, anatomic deformities, and, in some cases, death. Due to the high post-excision recurrence rate (21-29%) and frequent spontaneous regression or stabilization (50-88%), active surveillance is the first-line treatment for desmoid tumors. Most therapeutic agents only achieve tumor stability a
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Mallouh, Ahmad A. "Congenital Desmoid Tumor." Annals of Saudi Medicine 13, no. 5 (1993): 477–78. http://dx.doi.org/10.5144/0256-4947.1993.477.

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D’Hooghe, L., S. Dekeyzer, T. Dewaele, K. Gieraerts, and K. Coenegrachts. "Intrathoracic Desmoid Tumor." Journal of the Belgian Society of Radiology 99, no. 1 (2015): 123–24. http://dx.doi.org/10.5334/jbr-btr.834.

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Soysal, O., and H. I. Libshitz. "Diaphragmatic desmoid tumor." American Journal of Roentgenology 166, no. 6 (1996): 1496–97. http://dx.doi.org/10.2214/ajr.166.6.8633477.

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Pignatti, G., G. Barbanti-Br??dano, D. Ferrari, et al. "Extraabdominal Desmoid Tumor." Clinical Orthopaedics and Related Research 375 (June 2000): 207–13. http://dx.doi.org/10.1097/00003086-200006000-00025.

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Romaní, Jorge, Mireia Yébenes, Oscar Escuder, et al. "Cutaneous Desmoid Tumor." Dermatologic Surgery 35, no. 10 (2009): 1582–87. http://dx.doi.org/10.1111/j.1524-4725.2009.01280.x.

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Anderson, Timothy, Gregory S. Weinstein, John Harwick, and David I. Rosenthal. "Hypopharyngeal Desmoid Tumor." Otolaryngology–Head and Neck Surgery 123, no. 3 (2000): 279–81. http://dx.doi.org/10.1067/mhn.2000.104521.

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Pereyo, Neville G., and William L. Heimer. "Extraabdominal desmoid tumor." Journal of the American Academy of Dermatology 34, no. 2 (1996): 352–56. http://dx.doi.org/10.1016/s0190-9622(07)80007-7.

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Posner, Mitchell C. "The Desmoid Tumor." Archives of Surgery 124, no. 2 (1989): 191. http://dx.doi.org/10.1001/archsurg.1989.01410020061010.

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Gluck, Robert W., Glenn Bloiso, and Jeffrey Glasser. "Paratesticular desmoid tumor." Urology 29, no. 6 (1987): 648–49. http://dx.doi.org/10.1016/0090-4295(87)90114-2.

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Othman, CHAMA, OUADDANE ALAMI Rhyan, BOUCHTIB Amine, et al. "Giant intra-abdominal and retroperitoneal desmoid tumor." World Journal of Advanced Research and Reviews 17, no. 3 (2023): 579–82. https://doi.org/10.5281/zenodo.8133084.

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Desmoid tumors are extremely rare. They represent 3% of all soft tissue tumors. Giant desmoid tumors are rarely reported in the literature and are a challenge in their therapeutic management. The radiological evaluation of extension allowed to delimit its extension in depth and its limits of exeresis. In our case, the tumor was surgically resected with simple postoperative care. This case illustrates the difficulties of managing this entity given its large size.
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Napolitano, Andrea, Alessandro Mazzocca, Mariella Spalato Ceruso, et al. "Recent Advances in Desmoid Tumor Therapy." Cancers 12, no. 8 (2020): 2135. http://dx.doi.org/10.3390/cancers12082135.

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The desmoid tumor is a locally aggressive proliferative disease within the family of soft-tissue sarcomas. Despite its relatively good prognosis, the clinical management of desmoid tumors requires constant multidisciplinary evaluation due to its highly variable clinical behavior. Recently, active surveillance has being regarded as the appropriate strategy at diagnosis, as indolent persistence or spontaneous regressions are not uncommon. Here, we review the most recent advances in desmoid tumor therapy, including low-dose chemotherapy and treatment with tyrosine kinase inhibitors. We also explo
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Arzoo, Shabera, Mst Shamima Akter, Saima Afroz, Md Ataur Rahman, and Maher Akther. "Desmoid Tumor of the Abdominal Wall: A Case Report." Eastern Medical College Journal 7, no. 2 (2023): 28–31. http://dx.doi.org/10.3329/emcj.v7i2.64314.

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Desmoid tumors alternatively known as aggressive fibromatosis are benign myofibroblastic neoplasms originating from the muscle aponeurosis and classified as deep fibromatoses and these tumors are non-cancerous growth that occurs in the connective tissue. These tumors constitute 3% of all soft tissue tumors and 0.03% of all neoplasms and they occur usually between the age group of 20-40 years with a strong prevalence among women with fertile age group. In female patients presenting a tumor of the lower abdominal wall especially after cesarian section, an endometriotic tumor as well as an aggres
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Anwar, Sami Al-khalifah Ibrahim abdulmonem Al-majed Fatimah Sami Al-khalifah Dr Hameed Aljawad Dr Mohomad Chour Abdullah Jameel Al-majed Ahmed Ali Al-ghamdi Abdulaziz Hisham Al-ghassab Boshra Mohammad Masmali. "ABDOMINAL WALL DESMOID TUMOR: TYPICAL PRESENTATION OF A RARE DISEASE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 11 (2018): 11926–31. https://doi.org/10.5281/zenodo.1483517.

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<em>Desmoid tumors are rare slow growing benign but locally aggressive tumors with known local recurrence and no metastatic potentials. They account for 3% of all soft tissue tumors and 0.03% of all neoplasms. Definitive treatment of abdominal wall desmoid tumor is wide local excision with reconstruction of the defect. We report a case of a young female patient who presented with right lower abdominal wall mass. Preoperative evaluation included ultrasonography, CT scan and a diagnostic tissue biopsy. The patient was treated successfully by laparoscopic surgery with wide local excision.</em> <s
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Rodrigues, Gabriel, Devesh Sanjeev Ballal, Kantilatha Pai, Sunitha Carnelio, Vikas Singhal, and Shakeel Akhtar. "Facial fibromatosis: benign and aggressive, yet treatable!" Journal of Oral Medicine and Oral Surgery 25, no. 3 (2019): 29. http://dx.doi.org/10.1051/mbcb/2019022.

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Fibromatosis or desmoid tumors are locally aggressive neoplasms that have a propensity for local invasion and recurrence. The mainstay of treatment is excision with negative margins and the role of radiotherapy is controversial. Desmoids arising in the head and neck area are rare and pose a dilemma to the surgeon due to large number of vital structures that preclude resection with wide margins. This leads to a high incidence of recurrence. We present a case of a 24-year-old male who presented with an asymptomatic left sided facial swelling causing cosmetic deformity. A subcutaneous lipoma/fibr
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Kusum Meena, Manchikanti Dinesh, and M M Ramshankar. "Unusual Cause for Post Pregnancy Abdominal Bulge: A Large Desmoid Tumor." IAR Journal of Medicine and Surgery Research 2, no. 3 (2021): 10–13. http://dx.doi.org/10.47310/iarjmsr.2021.v02i03.03.

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Desmoid tumors are rare tumors which have shown a recent change in treatment from surgical option to more conservative modalities including use of noval molecular targeted therapy in form of receptor kinase inhibitors .More understanding towards tumor biology and behaviour brought the concept of individualized treatment for this rare tumor. Abdominal wall desmoid tumors have predilection for female patients of reproductive age group and watchful waiting can be judiciously used as therapeutic option in a large number of cases after more familiarity with tumor biology.
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Turupaev, Kirill A., Marina D. Budurova, and Maxim P. Nikulin. "Immediate and long-term outcomes of surgical treatment in patients with retroperitoneal and abdominal desmoid fibromatosis: A retrospective study." Journal of Modern Oncology 26, no. 2 (2024): 218–23. http://dx.doi.org/10.26442/18151434.2024.2.202750.

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Background. The main method of treatment of desmoid fibromatosis is surgical, especially in patients with symptomatic disease or in cases of progression during the Look and Stay period. Due to the rarity of the disease, different localization, unpredictability of the clinical course, the lack of generally accepted clear criteria for choosing a treatment method and/or a sequence of treatment methods, the determination of prognostic criteria for the course of the disease is of great scientific and practical interest. Aim. To study the immediate and long-term outcomes of surgical treatment in pat
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TITOU, Dr ANOUAR, Dr IKRAME BEJJA, Dr MOHAMMED ESSIOTI, Pr ZAKIA DOUHI, Pr FATIMA ZAHRAE MERNISSI, and Pr DOUNIA KAMAL. "A Rare Case Of Desmoid Tumor In The Lower Mandibular Sector Of An Adolescent: Surgical Intervention And Outcomes." International Journal of Medical Science and Dental Health 10, no. 10 (2024): 14–18. http://dx.doi.org/10.55640/ijmsdh-10-10-03.

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Introduction: Desmoid tumors are rare, benign neoplasms known for their locally aggressive behavior and high recurrence rates. They arise from fibroblasts and are characterized by their infiltrative growth, making surgical management challenging. This report presents a case of a desmoid tumor in the lower mandibular sector of a 16-year-old male, focusing on surgical intervention and molecular insights. Case Report: A 16-year-old male presented with a growing mass in the lower right mandible, causing pain and mobility of tooth 47. Imaging revealed an infiltrative lesion eroding the mandibular b
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Ilhami, Ouail, Hamza Sobhi, Badreddine Belmadani, Abdelhakim Oukerroum, and Faiçal Slimani. "Orbital Desmoid Tumor Complicated with Corneal Abscess: A Challenging Case." Scholars Journal of Medical Case Reports 13, no. 02 (2025): 240–45. https://doi.org/10.36347/sjmcr.2025.v13i02.006.

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Desmoid tumor is a benign fibrous neoplasia arising from the musculoaponeurotic structures of the muscles. They are characterized by their infiltrative and locally aggressive behavior with tendency for recurrence. Orbital location is extremely rare, only a few separate cases have been reported in the literature and are mainly pediatric. In this article, we report the case of an adult patient affected with a locally aggressive desmoid tumor involving the orbit that was unsuccessfully treated with hormonal therapy then by chemotherapy which induced a hematological toxicity before undergoing the
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Oh, Jin Seok, Jin Hye Kwak, Seon Min Jung, and Jin Hyeok Jeong. "A Case of Nasal Desmoid Tumor." Korean Journal of Otorhinolaryngology-Head and Neck Surgery 65, no. 12 (2022): 839–42. http://dx.doi.org/10.3342/kjorl-hns.2022.00857.

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Desmoid fibromatosis is a very slowly growing benign fibroblast tumor. Locally aggressive and non-metastasizing, it is a well-differentiated, unencapsulated monoclonal myofibroblastic proliferation that has a tendency for local invasion and recurrence. About 15% of all desmoidtype fibromatosis develops within the head and neck. The majority of head and neck desmoid tumor is located in the neck, but less frequently in the face, scalp, oral cavity, mandible, paranasal sinuses, orbit, ear and other structures. We report a very rare case in a 55-year-old female of a desmoid fibromatosis arising fr
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