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Articles de revues sur le sujet "Cpet, metabolic syndrome, exercise"

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Folope, Vanessa, Caroline Meret, Ingrid Castres, Claire Tourny, Estelle Houivet, Sébastien Grigioni, Hélène Lelandais et al. « Evaluation of a Supervised Adapted Physical Activity Program Associated or Not with Oral Supplementation with Arginine and Leucine in Subjects with Obesity and Metabolic Syndrome : A Randomized Controlled Trial ». Nutrients 14, no 18 (8 septembre 2022) : 3708. http://dx.doi.org/10.3390/nu14183708.

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Background: In patients with obesity and metabolic syndrome (MetS), lifestyle interventions combining diet, in particular, and physical exercise are recommended as the first line treatment. Previous studies have suggested that leucine or arginine supplementation may have beneficial effects on the body composition or insulin sensitivity and endothelial function, respectively. We thus conducted a randomized controlled study to evaluate the effects of a supervised adapted physical activity program associated or not with oral supplementation with leucine and arginine in MetS-complicated patients with obesity. Methods: Seventy-nine patients with obesity and MetS were randomized in four groups: patients receiving arginine and leucine supplementation (ALs group, n = 20), patients on a supervised adapted physical activity program (APA group, n = 20), patients combining ALs and APA (ALs+APA group, n = 20), and a control group (n = 19). After the baseline evaluation (m0), patients received ALs and/or followed the APA program for 6 months (m6). Body composition, MetS parameters, lipid and glucose metabolism markers, inflammatory markers, and a cardiopulmonary exercise test (CPET) were assessed at m0, m6, and after a 3-month wash-out period (m9). Results: After 6 months of intervention, we did not observe variable changes in body weight, body composition, lipid and glucose metabolism markers, inflammatory parameters, or quality of life scores between the four groups. However, during the CPET, the maximal power (Pmax and Ppeak), power, and O2 consumption at the ventilatory threshold (P(VT) and O2(VT)) were improved in the APA and ALs+APA groups (p < 0.05), as well as the forced vital capacity (FVC). Between m6 and m9, a gain in fat mass was only observed in patients in the APA and ALs+APA groups. Conclusion: In our randomized controlled trial, arginine and leucine supplementation failed to improve MetS in patients with obesity, as did the supervised adapted physical activity program and the combination of both. Only the cardiorespiratory parameters were improved by exercise training.
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Winkert, K., et J. Kirsten. « Cardiopulmonary exercise testing – methodological aspects ». Deutsche Zeitschrift für Sportmedizin/German Journal of Sports Medicine 73, no 5 (1 septembre 2022) : 184–88. http://dx.doi.org/10.5960/dzsm.2022.538.

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Cardiopulmonary exercise testing (CPET) allows for a non-invasive assessment of the integrative response of the pulmonary, cardiovascular, and skeletal muscle system during exercise. Therefore CPET in sports medicine covers a wide spectrum, ranging from diagnosis of disease, preoperative assessment, to athlete monitoring. High standards of reliability and validity are needed to ensure high-quality and diagnostically conclusive CPET data, necessitating a systematic process of quality assurance and control in the daily application of CPET. Therefore, methodological aspects such as CPET equipment principles, calibration, verification, maintenance, preparation, and plausibility checks need to be considered. As inter-technology, inter-device, and inter-unit differences in reliability and validity are reported for automated metabolic analyzers, the choice of the appropriate device should follow the purpose of use and comprehensible data on reliability and validity. To ensure high-quality measurements, careful calibration, and verification of all sensors, the integrated overall measurement performance, and maintenance of all equipment need to be performed and monitored longitudinally. Further, standardized ambient conditions, with adequate circulation and exchange of room air are essential. As the choice of the ergometer and protocol influences various target values in CPET, appropriateness for the selected diagnostic objective as well as a corresponding standardization is needed. While patients should receive pretest information that clearly outlines the test procedure, the correct attachment of the CPET equipment is of utmost importance. To detect and correct malfunctions of the metabolic analyzer and equipment, plausibility checks of the outcome measures validity should be performed during the resting, unloaded, loaded, and recovery test phase. A basic plausibility check should include adequate rest values and increases for a given workload rate of minute ventilation ( ˙VE), oxygen consumption ( ˙VO2) and respiratory exchange ratio (RER), using rules of thumb by Rühle. Before the final data interpretation is performed, e.g. ventilatory threshold or maximum oxygen consumption (˙VO2max) or ˙VO2peak determination, again a plausibility check should be performed and the patient‘s effort whether or not maximal should be determined. Consequently, a standard operating procedure for quality assurance and control, including an intuitive data visualization with thresholds for “pass”, “fail” or outliers and trends of concerns should be specifically defined, taught, and implemented in each facility. Key Words: CPET, Exercise Testing, Physical Fitness
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Laveneziana, Pierantonio, Marcello Di Paolo et Paolo Palange. « The clinical value of cardiopulmonary exercise testing in the modern era ». European Respiratory Review 30, no 159 (6 janvier 2021) : 200187. http://dx.doi.org/10.1183/16000617.0187-2020.

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Cardiopulmonary exercise testing (CPET) has long been used as diagnostic tool for cardiac diseases. During recent years CPET has been proven to be additionally useful for 1) distinguishing between normal and abnormal responses to exercise; 2) determining peak oxygen uptake and level of disability; 3) identifying factors contributing to dyspnoea and exercise limitation; 4) differentiating between ventilatory (respiratory mechanics and pulmonary gas exchange), cardiovascular, metabolic and peripheral muscle causes of exercise intolerance; 5) identifying anomalies of ventilatory (respiratory mechanics and pulmonary gas exchange), cardiovascular and metabolic systems, as well as peripheral muscle and psychological disorders; 6) screening for coexistent ischaemic heart disease, peripheral vascular disease and arterial hypoxaemia; 7) assisting in planning individualised exercise training; 8) generating prognostic information; and 9) objectively evaluating the impact of therapeutic interventions. As such, CPET is an essential part of patients' clinical assessment. This article belongs to the special series on the “Ventilatory efficiency and its clinical prognostic value in cardiorespiratory disorders”, addressed to clinicians, physiologists and researchers, and aims at encouraging them to get acquainted with CPET in order to help and orient the clinical decision concerning individual patients.
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Sridhar, M. K., R. Carter, S. W. Banham et F. Moran. « An Evaluation of Integrated Cardiopulmonary Exercise Testing in a Pulmonary Function Laboratory ». Scottish Medical Journal 40, no 4 (août 1995) : 113–16. http://dx.doi.org/10.1177/003693309504000404.

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Clinical exercise testing has been used mainly to assess the cardiac response to exercise. Integrative cardiopulmonary exercise tests (CPET) involving the measurement of the ventilatory, circulatory and metabolic response to exercise has largely been a research tool. We analysed the results of one hundred tests randomly chosen from a total of 472 exercise tests performed between January 1992 and June 1993 as clinical investigation in a pulmonary function laboratory. CPET was used (a) to identify the cause of effort limitation in patients where more than one illness could be relevant (26); (b) to obtain an objective measure of the exercise capacity of patients with respiratory or cardiac disease (31); (c) as monitor of response to treatment (11) and (d) in the investigation of unexplained dyspnoea (32). In 94 of the 100 cases CPET was able to provide an answer to the specific clinical question posed. In patients with unexplained dyspnoea CPET identified a group who exhibit an inappropriate hyperventilatory response to exercise with no supportive evidence of cardiopulmonary disease. In a small minority of cases CPET gave non-specific results. We conclude that CPET is a useful investigation in the management of patients with cardiopulmonary disease and complements the various other investigations offered by a pulmonary function laboratory.
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Mazaheri, Reza, Christian Schmied, David Niederseer et Marco Guazzi. « Cardiopulmonary Exercise Test Parameters in Athletic Population : A Review ». Journal of Clinical Medicine 10, no 21 (29 octobre 2021) : 5073. http://dx.doi.org/10.3390/jcm10215073.

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Although still underutilized, cardiopulmonary exercise testing (CPET) allows the most accurate and reproducible measurement of cardiorespiratory fitness and performance in athletes. It provides functional physiologic indices which are key variables in the assessment of athletes in different disciplines. CPET is valuable in clinical and physiological investigation of individuals with loss of performance or minor symptoms that might indicate subclinical cardiovascular, pulmonary or musculoskeletal disorders. Highly trained athletes have improved CPET values, so having just normal values may hide a medical disorder. In the present review, applications of CPET in athletes with special attention on physiological parameters such as VO2max, ventilatory thresholds, oxygen pulse, and ventilatory equivalent for oxygen and exercise economy in the assessment of athletic performance are discussed. The role of CPET in the evaluation of possible latent diseases and overtraining syndrome, as well as CPET-based exercise prescription, are outlined.
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Gille, Thomas, et Pierantonio Laveneziana. « Cardiopulmonary exercise testing in interstitial lung diseases and the value of ventilatory efficiency ». European Respiratory Review 30, no 162 (30 novembre 2021) : 200355. http://dx.doi.org/10.1183/16000617.0355-2020.

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Interstitial lung diseases (ILDs) are diverse parenchymal pulmonary disorders, primarily characterised by alveolar and interstitial inflammation and/or fibrosis, and sharing pathophysiological similarities. Thus, patients generally harbour common respiratory symptoms, lung function abnormalities and modified exercise adaptation. The most usual and disabling complaint is exertional dyspnoea, frequently responsible for premature exercise interruption. Cardiopulmonary exercise testing (CPET) is increasingly used for the clinical assessment of patients with ILD. This is because exercise performance or dyspnoea on exertion cannot reliably be predicted by resting pulmonary function tests. CPET, therefore, provides an accurate evaluation of functional capacity on an individual basis. CPET can unmask anomalies in the integrated functions of the respiratory, cardiovascular, metabolic, peripheral muscle and neurosensory systems in ILDs. CPET uniquely provides an evaluation of all above aspects and can help clinicians shape ILD patient management. Preliminary evidence suggests that CPET may also generate valuable prognostic information in ILDs and can be used to shed light on the presence of associated pulmonary hypertension. This review aims to provide comprehensive and updated evidence concerning the clinical utility of CPET in ILD patients, with particular focus on the physiological and clinical value of ventilatory efficiency (V˙E/V˙CO2).
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Pella, Eva, Afroditi Boutou, Marieta P. Theodorakopoulou et Pantelis Sarafidis. « Assessment of Exercise Intolerance in Patients with Pre-Dialysis CKD with Cardiopulmonary Function Testing : Translation to Everyday Practice ». American Journal of Nephrology 52, no 4 (2021) : 264–78. http://dx.doi.org/10.1159/000515384.

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<b><i>Background:</i></b> Chronic kidney disease (CKD) is often characterized by increased prevalence of cardiovascular risk factors and increased incidence of cardiovascular events and death. Reduced cardiovascular reserve and exercise intolerance are common in patients with CKD and are associated with adverse outcomes. <b><i>Summary:</i></b> The gold standard for identifying exercise limitation is cardiopulmonary exercise testing (CPET). CPET provides an integrative evaluation of cardiovascular, pulmonary, hematopoietic, neuropsychological, and metabolic function during maximal or submaximal exercise. It is useful in clinical setting for differentiation of the causes of exercise intolerance, risk stratification, and assessment of response to relevant treatments. A number of recent studies have used CPET in patients with pre-dialysis CKD, aiming to assess the cardiovascular reserve of these individuals, as well as the effect of interventions such as exercise training programs on their functional capacity. This review provides an in-depth description of CPET methodology and an overview of studies that utilized CPET technology to assess cardiovascular reserve in patients with pre-dialysis CKD. <b><i>Key Messages:</i></b> CPET can delineate multisystem changes and offer comprehensive phenotyping of factors determining overall cardiovascular risk. Potential clinical applications of CPET in CKD patients range from objective diagnosis of exercise intolerance to preoperative and long-term risk stratification and providing intermediate endpoints for clinical trials. Future studies should delineate the association of CPET indexes, with cardiovascular and respiratory alterations and hard outcomes in CKD patients, to enhance its diagnostic and prognostic utility in this population.
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van Campen, C. (Linda) M. C., et Frans C. Visser. « Comparing Idiopathic Chronic Fatigue and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Males : Response to Two-Day Cardiopulmonary Exercise Testing Protocol ». Healthcare 9, no 6 (5 juin 2021) : 683. http://dx.doi.org/10.3390/healthcare9060683.

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(1) Introduction: Multiple studies have shown that peak oxygen consumption is reduced in the majority of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS )patients, using the gold standard for measuring exercise intolerance: cardiopulmonary exercise testing (CPET). A 2-day CPET protocol has shown different results on day 2 in ME/CFS patients compared to sedentary controls. No comparison is known between ME/CFS and idiopathic chronic fatigue (ICF) for 2-day CPET protocols. We compared ME/CFS patients with patients with chronic fatigue who did not fulfill the ME/CFS criteria in a male population and hypothesized a different pattern of response would be present during the 2nd day CPET. (2) Methods: We compared 25 male patients with ICF who had completed a 2-day CPET protocol to an age-/gender-matched group of 26 male ME/CFS patients. Measures of oxygen consumption (VO2), heart rate (HR), systolic and diastolic blood pressure, workload (Work), and respiratory exchange ratio (RER) were collected at maximal (peak) and ventilatory threshold (VT) intensities. (3) Results: Baseline characteristics for both groups were similar for age, body mass index (BMI), body surface area, (BSA), and disease duration. A significant difference was present in the number of patients with fibromyalgia (seven ME/CFS patients vs. zero ICF patients). Heart rate at rest and the RER did not differ significantly between CPET 1 and CPET 2. All other CPET parameters at the ventilatory threshold and maximum exercise differed significantly (p-value between 0.002 and <0.0001). ME/CFS patients showed a deterioration of performance on CPET2 as reflected by VO2 and workload at peak exercise and ventilatory threshold, whereas ICF patients showed improved performance on CPET2 with no significant change in peak workload. (4) Conclusion: This study confirms that male ME/CFS patients have a reduction in exercise capacity in response to a second-day CPET. These results are similar to published results in male ME/CFS populations. Patients diagnosed with ICF show a different response on day 2, more similar to sedentary and healthy controls.
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van Campen, C. (Linda) M. C., et Frans C. Visser. « Female Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome or Idiopathic Chronic Fatigue : Comparison of Responses to a Two-Day Cardiopulmonary Exercise Testing Protocol ». Healthcare 9, no 6 (5 juin 2021) : 682. http://dx.doi.org/10.3390/healthcare9060682.

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Introduction: Multiple studies have shown that peak oxygen consumption is reduced in the majority of ME/CFS patients, using the golden standard for measuring exercise intolerance: cardiopulmonary exercise testing (CPET). A 2-day CPET protocol has shown different results on day 2 in ME/CFS patients compared to sedentary controls. No comparison is known between ME/CFS and idiopathic chronic fatigue (ICF) for 2-day CPET protocols. We compared ME/CFS patients with patients with chronic fatigue who did not fulfil the ME/CFS criteria in a male population and hypothesized a different pattern of response would be present during the 2nd day CPET. Methods: Fifty-one female patients with ICF completed a 2-day CPET protocol and were compared to an age/sex-matched group of 50 female ME/CFS patients. Measures of oxygen consumption (VO2), heart rate (HR), systolic and diastolic blood pressure, workload (Work), and respiratory exchange ratio (RER) were collected at maximal (peak) and ventilatory threshold (VT) intensities. Results: Baseline characteristics for both groups were similar for age, BMI, BSA, and disease duration. A significance difference was present in the number of patients with fibromyalgia (seven ME/CFS patients vs zero ICF patients). Heart rate at rest and the RER did not differ significantly between CPET 1 and CPET 2. All other CPET parameters at the ventilatory threshold and maximum exercise differed significantly (p-value between 0.002 and <0.0001). ME/CFS patients showed a deterioration of performance on CPET2 as reflected by VO2 and workload at peak exercise and ventilatory threshold, whereas ICF patients showed improved performance on CPET2 with no significant change in peak workload. Conclusion: This study confirms that female ME/CFS patients have a reduction in exercise capacity in response to a second day CPET. These results are similar to published results in female ME/CFS populations. Patients diagnosed with ICF show a different response on day 2, more similar to sedentary and healthy controls.
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Miki, Keisuke. « Motor Pathophysiology Related to Dyspnea in COPD Evaluated by Cardiopulmonary Exercise Testing ». Diagnostics 11, no 2 (21 février 2021) : 364. http://dx.doi.org/10.3390/diagnostics11020364.

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In chronic obstructive pulmonary disease (COPD), exertional dyspnea, which increases with the disease’s progression, reduces exercise tolerance and limits physical activity, leading to a worsening prognosis. It is necessary to understand the diverse mechanisms of dyspnea and take appropriate measures to reduce exertional dyspnea, as COPD is a systemic disease with various comorbidities. A treatment focusing on the motor pathophysiology related to dyspnea may lead to improvements such as reducing dynamic lung hyperinflation, respiratory and metabolic acidosis, and eventually exertional dyspnea. However, without cardiopulmonary exercise testing (CPET), it may be difficult to understand the pathophysiological conditions during exercise. CPET facilitates understanding of the gas exchange and transport associated with respiration-circulation and even crosstalk with muscles, which is sometimes challenging, and provides information on COPD treatment strategies. For respiratory medicine department staff, CPET can play a significant role when treating patients with diseases that cause exertional dyspnea. This article outlines the advantages of using CPET to evaluate exertional dyspnea in patients with COPD.
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Thèses sur le sujet "Cpet, metabolic syndrome, exercise"

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PASSONI, ELISABETTA ANGELA. « Prevention-treatment of metabolic syndrome based on CPET (cardio-pulmonary exercise test) ». Doctoral thesis, Università degli Studi di Milano-Bicocca, 2013. http://hdl.handle.net/10281/46813.

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We plan to evaluate (study period estimated in 6 months), the positive effects (decreased body weight, increased aerobic work capacity, changes in blood chemistry parameters, any change in drug therapy), of personalized physical training developed on the basis of metabolic parameter derived from a CPET. The index we propose to use for a correct prescription of exercise is the anaerobic threshold that represents the maximum aerobic potential of a subject.
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Mestek, Michael Louis. « The effects of sccumulated and continuous bouts of aerobic exercise and differing levels of exercise intensity on postprandial lipemia ». Auburn, Ala., 2007. http://repo.lib.auburn.edu/2007%20Spring%20Dissertations/MESTEK_MICHAEL_10.pdf.

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Stuart, Charles A., Mark A. South, Michelle L. Lee, Melanie P. McCurry, Mary E. A. Howell, Michael W. Ramsey et Michael H. Stone. « Insulin Responsiveness in Metabolic Syndrome after Eight Weeks of Cycle Training ». Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/4122.

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Introduction Insulin resistance in obesity is decreased after successful diet and exercise. Aerobic exercise training alone was evaluated as an intervention in subjects with the metabolic syndrome. Methods Eighteen nondiabetic, sedentary subjects, 11 with the metabolic syndrome, participated in 8 wk of increasing intensity stationary cycle training. Results Cycle training without weight loss did not change insulin resistance in metabolic syndrome subjects or sedentary control subjects. Maximal oxygen consumption (V˙O2max), activated muscle AMP-dependent kinase, and muscle mitochondrial marker ATP synthase all increased. Strength, lean body mass, and fat mass did not change. The activated mammalian target of rapamycin was not different after training. Training induced a shift in muscle fiber composition in both groups but in opposite directions. The proportion of type 2x fibers decreased with a concomitant increase in type 2a mixed fibers in the control subjects, but in metabolic syndrome, type 2x fiber proportion increased and type 1 fibers decreased. Muscle fiber diameters increased in all three fiber types in metabolic syndrome subjects. Muscle insulin receptor expression increased in both groups, and GLUT4 expression increased in the metabolic syndrome subjects. The excess phosphorylation of insulin receptor substrate 1 (IRS-1) at Ser337 in metabolic syndrome muscle tended to increase further after training in spite of a decrease in total IRS-1. Conclusions In the absence of weight loss, the cycle training of metabolic syndrome subjects resulted in enhanced mitochondrial biogenesis and increased the expression of insulin receptors and GLUT4 in muscle but did not decrease the insulin resistance. The failure for the insulin signal to proceed past IRS-1 tyrosine phosphorylation may be related to excess serine phosphorylation at IRS-1 Ser337, and this is not ameliorated by 8 wk of endurance exercise training.
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Taylor, Carmen L. « The effects of varying exercise volumes on the metabolic syndrome in women ». Virtual Press, 2003. http://liblink.bsu.edu/uhtbin/catkey/1273273.

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This study examined the trend of varying volumes of exercise on the risk factors embodying the metabolic syndrome in sedentary women (n=21, 49.2 ± 5.7 years). The following measurements: waist and hip circumference, weight, height, resting blood pressure, body composition, fasting levels of blood glucose, lipids, and insulin, peak V02 and treadmill time were measured at baseline and upon the completion of the study. Women were randomly assigned to one of three energy expenditure groups: 600 kcals/week (n=6), 800 kcals/week (n=8) or 1000 kcals/week (n=7). They were instructed to perform cardiovascular exercise three times a week for three months in a moderate exercise-training program with no modifications in their diet. The results revealed few significant changes in the risk factors embodying the metabolic syndrome. Nevertheless, these volumes of exercise were adequate in reducing at least one metabolic disorder in nearly half (48%) of our subject population. This impact of exercise on metabolic syndrome risk factors was clinically important because as metabolic disorders decreased so did the mortality risk from cardiovascular and coronary disease within these women.
School of Physical Education
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Kirby, Ricky McCoy. « Effects of Dietary and Exercise Interventions On The Incidence of Metabolic Syndrome ». UNF Digital Commons, 2009. http://digitalcommons.unf.edu/etd/200.

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Metabolic syndrome is a serious health problem in the United States. The presence of metabolic syndrome significantly increases the risk of developing type II diabetes and cardiovascular disease by producing a prothrombic state. The prothrombic state that results from the clustering of several independent cardiovascular risk factors within one individual increases the risk of micro and macro vascular changes and eventually to end organ damage. There is considerable evidence to support the serious nature of this medical condition. Medications used to treat the hypertension, diabetic, and dyslipidemia components of metabolic syndrome can be a significant drain on the monthly budget of individuals and families, especially if they do not have health insurance. Diet and exercise programs have been shown to be effective in reducing adiposity and decreasing insulin resistance. These changes in lifestyle may be adjuncts or a low cost alternative to expensive medications for some individuals. The purpose of this project was to identify the effect of an intensive dietary and exercise program on patients with metabolic syndrome. This study even with a small sample size (n = 5) showed that waist size, systolic blood pressure, diastolic blood pressure, and high density lipoprotein levels were trending towards levels that would remove the patient from the diagnosis of metabolic syndrome. The greatest benefit for the general population would result from intervention prior to a diagnosis of hypertension and diabetes and with medication naïve individuals. Early intervention would decrease the cost of medical treatment and hospitalizations.
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Frappier, Alexandrine. « The Metabolic Syndrome and the Effects of Different Types of Exercise Modalities in Adolescents with Obesity : a HEARTY Study ». Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/31970.

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Purpose: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities including high waist circumference and blood pressure, elevated triglyceride, glucose, and, insulin concentrations and low high density lipoprotein cholesterol concentrations. The prevalence of MetS in overweight and obese adolescents ranges from 10 to 66% depending of the definition used and the population studied. Obese adolescents are more prone to have MetS, highlighting the necessity of designing effective none pharmacological interventions targeting the specific needs of adolescents and to improve the management of the metabolic syndrome. Objectives: The objectives of this thesis were first, to perform a secondary data analysis of the Healthy Eating Aerobic and Resistance Training in Youth (HEARTY) trial to determine the effects of different modalities of exercise training on the prevalence of the MetS and second, to do a critical analysis of the literature surrounding the MetS concept and diagnostic for the pediatric population. Methods: Among the 304 participants of the HEARTY trial, 65 (21%) participants were classified as having MetS by the International Diabetes Federation. Measures of waist circumference, blood pressure, fasting plasma concentrations of lipids, glucose and insulin and prevalence of MetS were compared to baseline and post-6 months intervention (Aerobic training, Resistance training, Combined aerobic and resistance training and Control). Results: There were no significant changes in the prevalence of MetS within and between Aerobic, Resistance, Combined aerobic and resistance and Control groups after the 6-month intervention. However, significant improvements in MetS parameters were observed from baseline to post-intervention within groups. Aerobic and Resistance training alone significantly decreased waist circumference and systolic and diastolic blood pressure. Combined aerobic and resistance significantly decreased triglyceride concentrations and increased high density lipoprotein cholesterol concentrations whereas Control significantly decreased systolic blood pressure and insulin levels. Conclusions: Exercise, regardless of the modality, and diet counseling were not statistically effective for reducing the prevalence of MetS but did improve some of the independent MetS parameters. The absence of statistical difference in the prevalence of the MetS may be due to a lack of statistical power. Moreover, the critical analysis of the MetS literature bring us to conclude that the first step towards a standard definition of MetS for the adolescent population is to define the true clinical purpose of a MetS diagnostic in the pediatric population.
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South, Mark A., Andrew S. Layne, N. Travis Triplett, William A. Sands, Satoshi Mizuguchi, W. Guy Hornsby, Ashley Kavanaugh et Michael H. Stone. « Effects of Short‐Term Free‐Weight and Semi‐block Periodization Resistance Training on Metabolic Syndrome ». Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/5094.

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The effects of short-term resistance training on performance and health variables associated with prolonged sedentary lifestyle and metabolic syndrome (MS) were investigated. Resistance training may alter a number of health-related, physiological, and performance variables. As a result, resistance training can be used as a valuable tool in ameliorating the effects of a sedentary lifestyle including those associated with MS. Nineteen previously sedentary subjects (10 with MS and 9 with nonmetabolic syndrome [NMS]) underwent 8 weeks of supervised resistance training. Maximum strength was measured using an isometric midthigh pull and resulting force-time curve. Vertical jump height (JH) and power were measured using a force plate. The muscle cross-sectional area (CSA) and type were examined using muscle biopsy and standard analysis techniques. Aerobic power was measured on a cycle ergometer using a ParvoMedics 2400 Metabolic system. Endurance was measured as time to exhaustion on a cycle ergometer. After training, maximum isometric strength, JH, jump power, and V_ O2peak increased by approximately 10% (or more) in both the metabolic and NMS groups (both male and female subjects). Over 8 weeks of training, body mass did not change statistically, but percent body fat decreased in subjects with the MS and in women, and lean body mass increased in all groups (p # 0.05). Few alterations were noted in the fiber type. Men had larger CSAs compared those of with women, and there was a fiber-specific trend toward hypertrophy over time. In summary, 8 weeks of semiblock free-weight resistance training improved several performance variables and some cardiovascular factors associated with MS
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Dunn, Sarah Louise Medical Sciences Faculty of Medicine UNSW. « Effects of exercise and dietary intervention on metabolic syndrome markers of inactive premenopausal women ». Awarded by:University of New South Wales. Medical Sciences, 2009. http://handle.unsw.edu.au/1959.4/43914.

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The effects of exercise and dietary intervention on metabolic syndrome (Mets) markers of inactive premenopausal women were investigated. In Study I, early markers of MetS were examined in young, (21.2 ?? 0.3 years), healthy but unfit women (N = 66) consuming a processed food diet. A second aim was to examine the relationship between ethnic influences (European versus Chinese) and early markers of MetS (e.g., hyperinsulinemia). Study II compared the hormonal and metabolic responses to steady state exercise (SSE) and high intensity interval exercise (HIIE) in untrained young women (N = 18, 21.7 ?? 0.8 years). Women were further divided into high and low fasting insulin levels to determine if hyperinsulinemia influenced hormonal and metabolic response to SSE and HIIE. Study III examined the hormonal and metabolic response to a randomized controlled intervention named the Fish oil, Exercise and Mediterranean diet (FEM) trial. The FEM trial was conducted with overweight, inactive young (23.5 ?? 0.6 years) women (N = 56) for 12 weeks. Characteristics of a subset of women (N = 34, 23.5 ?? 0.7 years) in the FEM trial, non-responders (NRES), who did not lose weight (??? 1% loss in mass), were also examined. Metabolic profiles were developed based on body composition, aerobic fitness, blood markers, diet, resting metabolic rate, medical history, blood pressure, and autonomic function. Body composition was measured by skinfolds and girths, bioimpedance (Tanita, Japan), and Dual Energy X-Ray Absorptiometry. Peak oxygen uptake was assessed using an open circuit spirometer, TrueMax 2400 Metabolic Cart. Venepuncture and cannulation techniques were used for collecting blood samples that were also centrifuged and frozen for later analysis. In Study I young women who were physically unfit and consumed a processed food diet possessed high levels of fasting insulin, HOMA-IR (an insulin resistance index), and C-reactive protein (CRP). Insulin, p < .001, and HOMA-IR, p < .05, were significantly greater in Chinese Australians compared to European Australians, whereas plasma CRP levels were significantly, p < .05, lower. Significant differences, p < .05, existed between the groups with the Chinese Australians possessing lower body composition indices. However, ethnic differences still existed for insulin, HOMA-IR, and CRP after adjusting for body composition. Both groups consumed significantly high protein relative to their body mass. Thus, it appears that hyperinsulinemia is one of the earliest markers of MetS in young inactive females of both European and Asian descent who are unfit and consume a high level of dietary protein. In Study II, HIIE compared to SSE proved to be more effective at preventing an increase in insulin levels in the two hours after exercise. Resting respiratory quotient (RQ) was significantly lower, p < .05, following both HIIE and SSE, whereas plasma glycerol levels were higher, p = .06, suggesting greater lipolysis following HIIE. The women were divided by baseline fasting plasma insulin (> 9.98 ??IU/ml) into high insulin (HI) and low insulin groups (LI). The fasting plasma human growth hormone levels of the HI women were significantly lower at baseline compared to that of LI women. Baseline RQ was correlated with baseline glycerol, r = - .54, p < .05. Insulin levels at one hour post HIIE was related to fasting plasma adrenocorticotropic hormone (ACTH) one hour post exercise, r = .52, p < .05. Fasting plasma leptin at one, r = .56, p < .05, and two, r = .53, p < .05, hours post exercise was associated with 2 hour post insulin levels. Interestingly, fasting ACTH was significantly elevated in the 2 hours post exercise in the HI women compared to LI. All diet data between the groups were similar and lipids were in the healthy range with no significant differences between the women possessing high or low fasting plasma insulin. Thus, young women who completed one session of short duration HIIE compared to SSE improved certain aspects of their metabolic profile (e.g., reduced insulin levels) and enhanced their fat oxidation in the immediate two-hour exercise recovery period. Following FEM (a 12-week multi-component lifestyle intervention) overweight women recorded significantly lower, p < .05, body composition (mass, fat mass, percent body fat, waist circumference), insulin, inflammation (CRP), blood pressure, and lipids. The improvements within the Mediterranean diet (Mediet) were related to the reductions in body weight, fat mass, and insulin. Consumption of saturated fats, legumes, meat, poultry, and egg were also significantly decreased, p < .05, following the trial. Adherence to the Mediet and fish oil consumption, measured through a Mediet score, was significantly increased, p < .001, and was associated with reduced levels of fat mass, r = .43, p < .05. Autonomic function (measured by power frequency analysis), aerobic fitness, and fat oxidation were all significantly, p < .05, enhanced. Therefore, an intervention incorporating fish oil consumption, HIIE, and Mediet significantly reduced body fat, fasting insulin, inflammatory markers, and some blood lipids. Interestingly, some women did not lose fat mass following the FEM intervention, despite experiencing significant reductions in insulin, inflammation, waist circumference, blood pressure, and an increase in aerobic power. The major differences between those women who lost fat and those that did not was that the non-responders possessed significantly lower, p < .05, systolic blood pressure, lower resting heart rate, and a higher resting RQ. In summary, in Study I, young, unfit women consuming a processed diet, demonstrated hyperinsulinemia and low grade inflammation. The high levels of fasting insulin suggest that these women are at a higher risk for developing MetS and type 2 diabetes. The results of Study II suggests that one bout of HIIE compared to a longer bout of SSE was more effective at preventing a rise in post-exercise insulin levels. Finally, results of Study III indicate that a 12-week lifestyle intervention, encompassing HIIE, fish oil ingestion, and a Mediet positively influenced early MetS markers (e.g., hyperinsulinemia), aerobic and anaerobic fitness, low grade inflammation, and body composition in young women.
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Ho, Thanh C. « Metabolic and biochemical responses during sustained forearm exercise in patients with chronic fatigue syndrome / ». Title page and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09SB/09sbh678.pdf.

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Thesis (B. Sc.(Hons.))--University of Adelaide, Dept. of Physiology, 1998?
Spine title: Metabolic responses during exercise in patients with chronic fatigue syndrome. Includes bibliographical references (leaves 14-16).
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Guo, Qianyu. « Skeletal muscle JNK activity after acute resistive exercise in elder adults with T2D : Metabolic and clinical correlates ». Thesis, The University of Sydney, 2011. http://hdl.handle.net/2123/7207.

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Objective This study describes the results of the baseline sub-study of a randomized double-blind, sham-exercise controlled trial designed to assess the efficacy of power training in older adults with type 2 diabetes. The primary purpose of this sub-study was to define the state of total and activated JNK in skeletal muscle which had been exposed to an acute resistive bout of exercise. In addition, metabolic and clinical characteristics were investigated in an attempt to explain the variance and the metabolic relevance of the JNK expression (total JNK, tJNK) and activation (ratio of phosphorylated/total JNK, p/tJNK) observed. We hypothsized that greater JNK expression and activation would be related to impaired health status, chronic inflammation, metabolic disturbance and insulin resistance in our cohort. We hypothsized that greater JNK expression and activation would be related to impaired health status (decreasing habitual exercise amount and burdens of diseases), chronic inflammation (increasing pro-inflammatory cytokines and decreasing anti-inflammatory cytokines), metabolic disturbance (disturbance of blood glucose and lipid regulation) and insulin resistance in our cohort. Methods Our cohort consisted of sedentary adults over 60 years of age with type 2 diabetes. The study recruited 103 participants from Aug 2006 to Dec 2009. Since the 50th participant completed theirassessments in Apr 2009 and this thesis was to be submitted in Aug 2010, it only included analysis of baseline data from the first 50 participants which were available at the time of submission. Insulin resistance was measured by homeostasis model assessment 2 (HOMA 2) computerized model; body composition was measured by computed tomography (CT) scan, bioelectric impedance analysis (BIA) and anthropometrics; glucose, insulin and serum cytokines (adiponectin, c-reactive protein (CRP) were measured by serum assays, factors related to the insulin signalling pathway obtained from skeletal muscle and subcutaneous adipose tissue biopsies (Insulin-like Growth Factor-1 (IGF-1), Tumour Necrosis Factor-α (TNFα), Interleukin 6 (IL-6), Heat Shock Protein 72 (HSP72), phospho-Jun N-terminal Kinase (pJNK) and total JNK (tJNK) in muscle, and Adiponetin, TNFα, IL-6 in adipose tissue) were measured by cytokine assays and Western Blot. The secondary outcomes, including health status, medications, physical performance and quality of life, were assessed by validated questionnaires. Results 35 of the 50 subjects had baseline measures of skeletal muscle JNK. As hypothesized, higher JNK was related or had the tendency to related to potentially poorer health status: number of medications/day(r=0.304, 0.081) and lower habitual physical activity (r=-0.333, p=0.055). Similarly, the relationships we found between total and activated JNK and anti-inflammatory/metabolic factors supported our hypotheses: higher tJNK was related to lower serum (r=-0.364, p=0.057) and adipose tissue (r=-0.465, p=0.060) HMW/adiponectin ratios, and higher p/tJNK was related to higher skeletal muscle IL-6 (rho=0.644, p<0.001), lower serum total (r=-0.336, p=0.081) and HMW adiponectin (r=-0.504, p=0.006), and lower HOMA β cell function (r=-0.332, p=0.055). By contrast, the relationships we found between JNK and systemic pro-inflammatory and local anabolic factors were inconsistent with our hypothesis. Specifically, higher tJNK was related to lower serum CRP (r=-0.457,p=0.015) and higher skeletal muscle IGF-1(r=0.641, p<0.001). Also contrary to our expectations, higher p/tJNK was related to lower serum total cholesterol (r=-0.059, p<0.001) and LDL (r=-0.401, p=0.016). Conclusion This was the first study to describe activated and total skeletal muscle JNK expression after acute resistive exercise in older adults with type 2 diabetes, and the first study to analyze potential correlations between skeletal muscle JNK and other aspects of health status, metabolism, and inflammation in this cohort. As hypothesized, higher JNK was related to more impaired health status (age, inactivity) and inversely related to anti-inflammatory adiponectin and HOMA2 β cell function. Unexpectedly, however, higher JNK was related to higher skeletal muscle IGF-1 and inversely related to CRP, serum total cholesterol and LDL. Additional studies are warranted to investigate whether chronic exercise training in type 2 diabetes alters the expression and activation of JNK, and to determine whether beneficial adaptations in JNK may explain a portion of the variance in exercise-related metabolic benefits in this cohort.
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Livres sur le sujet "Cpet, metabolic syndrome, exercise"

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Izumi, Tsuguhiko. Ishi ga susumeru uōkingu. Tōkyō : Shūeisha, 2005.

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1954-, Ochiai Toshi, dir. Koresuterōru chūsei sibō o gungun herasu daihyakka. Tōkyō : Shufu no Tomosha, 2006.

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Choifuto de daijōbu : Metaborikku shindorōmu ni naranai kotsu. Tōkyō : Shūeisha, 2006.

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Preventing Type 2 Diabetes : Beyond Diet and Exercise. BelVista Publishers, LLC, 2008.

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Metabolic Syndrome Exercise Protocols : Combining in 1 Volume : Hypertension and Dyslipidemia Exercise Protocols and Obesity and Diabetes Mellitus Exercise Protocols. Independently Published, 2020.

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Roberts, Justin. Physiological adaptations to the metabolic syndrome following exercise training and Omega-3 fatty acid supplementation. 1997.

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Egger, Garry. Quick Start (Quick Start Weight Loss Progra). Allen & Unwin (Australia) Pty Ltd, 2003.

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Skeletal muscle metabolic response to exercise in chronic fatigue syndrome determined by in vivo p31sP-NMR spectroscopy. 1993.

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FIRST Program : Fighting Insulin Resistance with Strength Training : Your Optimal Exercise Guide to Diabetes Prediabetes Metabolic Syndrome Cholesterol, a Science Based Approach. Independently Published, 2017.

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Barthel, Andreas, et Michael Bauer. Psychotropic drugs and metabolic risk. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198789284.003.0011.

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Increased appetite and weight gain represent a significant problem related with particular antipsychotic drugs, antidepressants, mood stabilizers, and—to a lesser extent—anxiolytic drugs. Psychotropic drug-induced weight gain may contribute to obesity-related metabolic changes and pathological conditions such as dyslipidaemia, type-2-diabetes and hypertension—summarized as the metabolic syndrome—with an increased risk for cardiovascular morbidity and mortality. Interestingly, psychotropic drugs are also used for the treatment of diabetes-related complications. For example, antidepressants are effective for the treatment of neuropathic pain in patients with diabetic neuropathy. Therefore, it is essential to thoroughly balance potential benefits and risks in an individual patient to ensure drug safety and optimize the clinical outcome. In addition to diet and exercise, selection of psychotropic drugs and dose adjustment based on regular clinical follow-up visits is the key for the prevention and management of psychotropic drug induced weight gain in clinical practice.
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Chapitres de livres sur le sujet "Cpet, metabolic syndrome, exercise"

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Brennan, Aoife M., Laura Sweeney et Christos S. Mantzoros. « The Metabolic Syndrome ». Dans Diabetes and Exercise, 69–81. Totowa, NJ : Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-260-1_3.

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Hu, Gang, Timo A. Lakka et Jaakko Tuomilehto. « Metabolic Syndrome ». Dans Encyclopedia of Exercise Medicine in Health and Disease, 566–69. Berlin, Heidelberg : Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-29807-6_209.

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Allison, Kelly C., et David B. Sarwer. « Diet, Exercise, and Behavior Therapy in the Treatment of Obesity and Metabolic Syndrome ». Dans Metabolic Syndrome, 783–95. Cham : Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-11251-0_43.

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Allison, Kelly C., et David B. Sarwer. « Diet, Exercise, and Behavior Therapy in the Treatment of Obesity and Metabolic Syndrome ». Dans Metabolic Syndrome, 1–14. Cham : Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-12125-3_43-1.

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Dipla, Konstantina, Andreas Zafeiridis et Karen M. Tordjman. « Metabolic Syndrome, Hormones, and Exercise ». Dans Endocrinology of Physical Activity and Sport, 519–34. Cham : Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-33376-8_29.

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McHugh, Cathy M., et Richard I. G. Holt. « Growth Hormone, Exercise and Energy Expenditure in the Metabolic Syndrome ». Dans The Metabolic Syndrome, 353–80. Chichester, UK : John Wiley & Sons, Ltd, 2006. http://dx.doi.org/10.1002/0470025131.ch14.

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Bray, George A. « Treatment of the Metabolic Syndrome with Weight Loss, Exercise, Hormones, and Surgery ». Dans The Metabolic Syndrome, 57–73. Totowa, NJ : Humana Press, 2008. http://dx.doi.org/10.1007/978-1-60327-116-5_4.

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Codario, Ronald A. « Exercise ». Dans Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome, 33–46. Totowa, NJ : Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60327-441-8_3.

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Nagi, Dinesh. « Exercise, Metabolic Syndrome and Type 2 Diabetes ». Dans Exercise and Sport in Diabetes, 77–93. Chichester, UK : John Wiley & Sons, Ltd, 2006. http://dx.doi.org/10.1002/0470022086.ch5.

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Saladini, F. « Metabolic Syndrome : Effect of Physical Activity on Arterial Elasticity ». Dans Exercise, Sports and Hypertension, 125–38. Cham : Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-07958-0_9.

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Actes de conférences sur le sujet "Cpet, metabolic syndrome, exercise"

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Adams-Campbell, Lucile L. « Abstract IA32 : Metabolic syndrome and breast cancer risk among black women : An exercise intervention ». Dans Abstracts : AACR International Conference : New Frontiers in Cancer Research ; January 18-22, 2017 ; Cape Town, South Africa. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.newfront17-ia32.

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Dieli-Conwright, Christina M., Frank C. Sweeney, Kerry S. Courneya, Debu Tripathy, Nathalie Sami, Kyuwan Lee, Thomas A. Buchanan et al. « Abstract C122 : Ethnicity as a moderator of the effects of aerobic and resistance exercise on metabolic syndrome in breast cancer survivors ». Dans Abstracts : Eleventh AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved ; November 2-5, 2018 ; New Orleans, LA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7755.disp18-c122.

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Kiwata, Jacqueline L., Tanya B. Dorff, E. T. Schroeder et Christina M. Dieli-Conwright. « Abstract 988 : Effect of a supervised exercise intervention on sarcopenic obesity and metabolic syndrome in prostate cancer patients : A randomized pilot study ». Dans Proceedings : AACR Annual Meeting 2017 ; April 1-5, 2017 ; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-988.

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Dieli-Conwright, CM, N. Sami, K. Lee, D. Spicer, TA Buchanan, W. Demark-Wahnefried, K. Courneya, D. Tripathy et J. Mortimer. « Abstract P5-13-01 : Effects of a 16-week combined aerobic and resistance exercise intervention on metabolic syndrome in overweight/Obese Hispanic breast cancer survivors ». Dans Abstracts : 2017 San Antonio Breast Cancer Symposium ; December 5-9, 2017 ; San Antonio, Texas. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.sabcs17-p5-13-01.

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Arisanti, Yuli, et Janri Manullang. « The Obesity Prevalence in Navy Personal and Civil Servants at Lantamal X Jayapura ». Dans The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.01.29.

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ABSTRACT Background: Central (visceral) obesity, one of the risk factors of metabolic syndrome, is becoming the major public health concern of non-communicable diseases. Predictions estimated that by 2030, 50% of adults will be listed as obese. This study aimed to examine smoking and exercise as the risk factors of central obesity in navy personal and civil servants at Lantamal X Jayapura. Subjects and Method: This was a cross sectional study conducted from November to December 2017 at Lantamal X Jayapura, Indonesia. A sample of 100 navy personal and civil servants was selected by random sampling. The dependent variable was central obesity. The independent variables were smoking and exercise. Waist circumference was measured by metline. The other variables were collected by questionnaires. Data were analyzed by Chi square. Results: The risk of central obesity increased with smoking (OR= 3.13; 95% CI= 1.63 to 5.98; p<0.001) and duration of exercise less than 60 minute per week (OR= 2.49; 95% CI= 1.14 to 5.40; p= 0.017). Conclusion: Risk of central obesity increases with smoking and duration of exercise. Keywords: central obesity, smoking, exercise, navy personal, civil servants Correspondence: Yuli Arisanti. National Institute of Health Research and Development Papua. Jl. Ahmad Yani No. 48, Gurabesi, Jayapura Utara. Email: yuliarisanti88@gmail.com. Mobile: +6281248978639. DOI: https://doi.org/10.26911/the7thicph.01.29
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