Bibliographies thématiques / CP26

Littérature scientifique sur le sujet « CP26 »

Auteur : Grafiati
Publié le 11 mars 2023

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Articles de revues sur le sujet "CP26"

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Friedrich, Carol, Monisha G. Scott, Nedra Karunaratne, Hong Yan et Robert E. W. Hancock. « Salt-Resistant Alpha-Helical Cationic Antimicrobial Peptides ». Antimicrobial Agents and Chemotherapy 43, no 7 (1 juillet 1999) : 1542–48. http://dx.doi.org/10.1128/aac.43.7.1542.

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ABSTRACT Analogues based on the insect cecropin–bee melittin hybrid peptide (CEME) were studied and analyzed for activity and salt resistance. The new variants were designed to have an increase in amphipathic α-helical content (CP29 and CP26) and in overall positive charge (CP26). The α-helicity of these peptides was demonstrated by circular dichroism spectroscopy in the presence of liposomes. CP29 was shown to have activity against gram-negative bacteria that was similar to or better than those of the parent peptides, and CP26 had similar activity. CP29 had cytoplasmic membrane permeabilization activity, as assessed by the unmasking of cytoplasmic β-galactosidase, similar to that of CEME and its more positively charged derivative named CEMA, whereas CP26 was substantially less effective. The activity of the peptides was not greatly attenuated by an uncoupler of membrane potential, carbonyl cyanide-m-chlorophenylhydrazone. The tryptophan residue in position 2 was shown to be necessary for interaction with cell membranes, as demonstrated by a complete lack of activity in the peptide CP208. Peptides CP29, CEME, and CEMA were resistant to antagonism by 0.1 to 0.3 M NaCl; however, CP26 was resistant to antagonism only by up to 160 mM NaCl. The peptides were generally more antagonized by 3 and 5 mM Mg2+ and by the polyanion alginate. It appeared that the positively charged C terminus in CP26 altered its ability to permeabilize the cytoplasmic membrane of Escherichia coli, although CP26 maintained its ability to kill gram-negative bacteria. These peptides are potential candidates for future therapeutic drugs.
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Kang, Ho Chul, Ji Hyung Chae, Yeon Ho Lee, Mi-Ae Park, June Ho Shin, Sung-Hyun Kim, Sang-Kyu Ye, Yoon Shin Cho, Steven Fiering et Chul Geun Kim. « Erythroid Cell-Specific α-Globin Gene Regulation by the CP2 Transcription Factor Family ». Molecular and Cellular Biology 25, no 14 (juillet 2005) : 6005–20. http://dx.doi.org/10.1128/mcb.25.14.6005-6020.2005.

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ABSTRACT We previously demonstrated that ubiquitously expressed CP2c exerts potent erythroid-specific transactivation of α-globin through an unknown mechanism. This mechanism is reported here to involve specific CP2 splice variants and protein inhibitor of activated STAT1 (PIAS1). We identify a novel murine splice isoform of CP2, CP2b, which is identical to CP2a except that it has an additional 36 amino acids encoded by an extra exon. CP2b has an erythroid cell-specific transcriptional activation domain, which requires the extra exon and can form heteromeric complexes with other CP2 isoforms, but lacks the DNA binding activity found in CP2a and CP2c. Transcriptional activation of α-globin occurred following dimerization between CP2b and CP2c in erythroid K562 and MEL cells, but this dimerization did not activate the α-globin promoter in nonerythroid 293T cells, indicating that an additional erythroid factor is missing in 293T cells. PIAS1 was confirmed as a CP2 binding protein by the yeast two-hybrid screen, and expression of CP2b, CP2c, and PIAS1 in 293T cell induced α-globin promoter activation. These results show that ubiquitously expressed CP2b exerts potent erythroid cell-specific α-globin gene expression by complexing with CP2c and PIAS1.
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Jackowski, Grzegorz, et Stefan Jansson. « Characterization of Photosystem II Antenna Complexes Separated by Non-Denaturing Isoelectric Focusing ». Zeitschrift für Naturforschung C 53, no 9-10 (1 octobre 1998) : 841–48. http://dx.doi.org/10.1515/znc-1998-9-1010.

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CP26, CP29 and three different LHC II subcomplexes have been purified from a carnation photosystem II (PSII) preparation using non-denaturing isoelectric focusing in a vertical polyacrylamide slab gel. The identity of the fractions was established by absorption spectroscopy, SDS-PAGE and immunoblotting. CP26 comprised a single apoprotein of 26.6 kDa and CP29 contained two apoproteins of 28.8 and 28.5 kDa. LHC II subcomplex A consisted of Lhcb1 homotrimers, and subcomplexes B and C consisted of Lhcb1/Lhcb2 and Lhcb1/Lhcb3 heterotrimers, respectively. We discuss the data in relation to the organization of the PS II antenna in vivo.
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Byram, Rebecca, Philip E. Stewart et Patricia Rosa. « The Essential Nature of the Ubiquitous 26-Kilobase Circular Replicon of Borrelia burgdorferi ». Journal of Bacteriology 186, no 11 (1 juin 2004) : 3561–69. http://dx.doi.org/10.1128/jb.186.11.3561-3569.2004.

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ABSTRACT The genome of the type strain (B31) of Borrelia burgdorferi, the causative agent of Lyme disease, is composed of 12 linear and 9 circular plasmids and a linear chromosome. Plasmid content can vary among strains, but one 26-kb circular plasmid (cp26) is always present. The ubiquitous nature of cp26 suggests that it provides functions required for bacterial viability. We tested this hypothesis by attempting to selectively displace cp26 with an incompatible but replication-proficient vector, pBSV26. While pBSV26 transformants contained this incompatible vector, the vector coexisted with cp26, which is consistent with the hypothesis that cp26 carries essential genes. Several cp26 genes with ascribed or predicted functions may be essential. These include the BBB29 gene, which has sequence homology to a gene encoding a glucose-specific phosphotransferase system component, and the resT gene, which encodes a telomere resolvase involved in resolution of the replicated telomeres of the linear chromosome and plasmids. The BBB29 gene was successfully inactivated by allelic exchange, but attempted inactivation of resT resulted in merodiploid transformants, suggesting that resT is required for B. burgdorferi growth. To determine if resT is the only cp26 gene essential for growth, we introduced resT into B. burgdorferi on pBSV26. This did not result in displacement of cp26, suggesting that additional cp26 genes encode vital functions. We concluded that B. burgdorferi plasmid cp26 encodes functions critical for survival and thus shares some features with the chromosome.
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Marr, K. M., D. N. Mastronarde et M. K. Lyon. « Two-dimensional crystals of photosystem II : biochemical characterization, cryoelectron microscopy and localization of the D1 and cytochrome b559 polypeptides. » Journal of Cell Biology 132, no 5 (1 mars 1996) : 823–33. http://dx.doi.org/10.1083/jcb.132.5.823.

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Photosystem II (PS II) is a photosynthetic reaction center found in higher plants which has the unique ability to evolve oxygen from water. Several groups have formed two-dimensional PS II crystals or have isolated PS II complexes and studied them by electron microscopy and image analysis. The majority of these specimens have not been well characterized biochemically and have yielded relatively low resolution two-dimensional projection maps with a variety of unit cell sizes. We report the characterization of the polypeptide and lipid content of tubular crystals of PS II. The crystals contain the reaction center core polypeptides D1, D2, cytochrome b559, as well as the chlorophyll-binding polypeptides (CP) CP47, CP43, CP29, CP26, CP24, and CP22. The lipid composition was similar to the lipids found in the stacked portion of thylakoids. We also report a 2.0-nm resolution projection map determined by electron microscopy and image analysis of frozen, hydrated PS II crystals. This projection map includes information on the portion of the complex buried in the lipid bilayer. The unit cell is a dimer with unit vectors of 17.0 and 11.4 nm separated by an angle of 106.6 degrees. In addition, Fab fragments against D1 and cytochrome b559 were used to localize those two polypeptides, and thus the reaction center, within the PS II complex. The results indicate that D1 and cytochrome b559 are found within one of the heaviest densities of the monomeric unit.
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Tilly, Kit, Lori Lubke et Patricia Rosa. « Characterization of Circular Plasmid Dimers inBorrelia burgdorferi ». Journal of Bacteriology 180, no 21 (1 novembre 1998) : 5676–81. http://dx.doi.org/10.1128/jb.180.21.5676-5681.1998.

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ABSTRACT We have inactivated the ospC, oppAIV, andguaB genes on the 26-kb circular plasmid of Borrelia burgdorferi (cp26) by allelic exchange. On several occasions following such transformations, the cp26 of transformants had an aberrant mobility through agarose gels. Characterization of these cp26 molecules showed that the plasmid had dimerized. These dimers were quite stable during either selective or nonselective passage. Subsequent transformations with dimer DNA supported the hypothesis that in B. burgdorferi, transforming cp26 DNA most likely does not displace the resident homologous plasmid but rather must recombine in order to donate sequences that it carries. These serendipitous findings provide a mechanism for obtaining heterozygous complemented control strains when mutant phenotypes are characterized.
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Olszówka, Dorota, Stanisław Krawczyk et Waldemar Maksymiec. « A study of molecular interactions in light-harvesting complexes LHCIIb, CP29, CP26 and CP24 by Stark effect spectroscopy ». Biochimica et Biophysica Acta (BBA) - Bioenergetics 1657, no 1 (juin 2004) : 61–70. http://dx.doi.org/10.1016/j.bbabio.2004.04.004.

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Amarie, Sergiu, Laura Wilk, Tiago Barros, Werner Kühlbrandt, Andreas Dreuw et Josef Wachtveitl. « Properties of zeaxanthin and its radical cation bound to the minor light-harvesting complexes CP24, CP26 and CP29 ». Biochimica et Biophysica Acta (BBA) - Bioenergetics 1787, no 6 (juin 2009) : 747–52. http://dx.doi.org/10.1016/j.bbabio.2009.02.006.

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Branton, Margaret A., Thomas H. MacRae, Fred Lipschultz et Peter G. Wells. « Identification of a small heat shock/α-crystallin protein in the scleractinian coral Madracis mirabilis (Duch. and Mitch.) ». Canadian Journal of Zoology 77, no 5 (1 octobre 1999) : 675–82. http://dx.doi.org/10.1139/z99-029.

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Immunological evidence is provided for the first time of a small heat shock/α-crystallin protein in the scleractinian coral Madracis mirabilis. The protein, termed cp26, had a molecular weight of 26 000; it reacted with an antibody raised to a small heat shock/α-crystallin protein fromArtemia franciscana and its production in corals was temperature sensitive. Corals collected from seawater at 25.5oC or lower lacked cp26, but the protein was produced in some of these animals when they were heat shocked experimentally. When exposed naturally to high environmental temperatures for relatively short times, corals contained cp26 and responded to heat shock in the laboratory. Corals growing at elevated temperatures tended to die when subjected to additional heat stress. Specifically, M. mirabilis died at about 31-33oC, as indicated by visual inspection of the animals, low recovery of protein in cell-free extracts, and loss of protein bands in SDS-polyacrylamide gels. Death was accompanied by the appearance of a diffuse, unidentified protein band on western blots that reacted with an antibody to cp26. Madracis mirabilis clearly reacts to heat shock by production of cp26; further study is required to determine if this small heat shock/α-crystallin protein will be a useful biomarker of stress in corals.
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Yakushevska, Alevtyna E., Wilko Keegstra, Egbert J. Boekema, Jan P. Dekker, Jenny Andersson, Stefan Jansson, Alexander V. Ruban et Peter Horton. « The Structure of Photosystem II inArabidopsis:Localization of the CP26 and CP29 Antenna Complexes† ». Biochemistry 42, no 3 (janvier 2003) : 608–13. http://dx.doi.org/10.1021/bi027109z.

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Thèses sur le sujet "CP26"

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Lahrhafi, Malika. « Élaboration et caractérisation de films amorphes Fe-O-C et Mo-O-C obtenus à partir de Fe2 Cp2 (CO)4 et Mo2 Cp2 (CO)6 ». Toulouse, INPT, 1987. http://www.theses.fr/1987INPT023G.

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Utilisation de molécules dinuclaires à l'état solide. Caractéristiques physicochimiques des molécules de départ et conditions d'élaboration des dépôts. Utilisation de ces matériaux dans le revêtement anticorrosion.
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Dubiella, Ullrich [Verfasser]. « Molekulare und biochemische Charakterisierung der Calcium-abhängigen Protein-Kinasen CPK5 und CPK6 aus Arabidopsis thaliana / Ullrich Dubiella ». Berlin : Freie Universität Berlin, 2009. http://d-nb.info/1023816296/34.

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Courtois, Julien. « Iridium-based bimetallic alloy catalysts for the ethanol oxidation reaction for fuel cells modeled by density functional theory ». Digital WPI, 2013. https://digitalcommons.wpi.edu/etd-theses/295.

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Current ethanol oxidation catalysts in direct ethanol fuel cells (typically platinum-based) suffer from low conversion and are susceptible to CO poisoning. Therefore we determined to find viable alternative catalysts for ethanol oxidation based on iridium using density functional theory to model bimetallic alloy (111) surfaces. Iridium was alloyed with another transition metals M in an overlayer (one layer of metal M on top of bulk iridium) or subsurface configuration (M is inserted under the first layer of iridium). Complete oxidation of ethanol is limited by the breaking of strong C-C bonds, so any catalyst must lower the barriers for C-C bond breaking. We modeled the reaction CH+CO →CHCO.Segregation energies were calculated and the subsurface configuration was the most stable configuration in the vast majority of alloy cases. CO adsorption was also studied and a lower CO adsorption energy was found in many alloy cases compared to pure Pt (, providing encouraging results about the possibility of reducing CO poisoning. Activation energies were lowered for the vast majority of the alloys used in an underlayer structure, reinforcing our interest in the underlayer structures or “subsurfaceâ€� alloys. Finally, we found, based on the CO adsorption energies, activation energies of the C-C breakage reaction, and metal cost, three important catalyst descriptors, a number of promising catalysts for the ethanol oxidation reaction. The most interesting alloys all adopted the underlayer structure Ir/M/Ir. With M = Ta, Hf, Nb, V, Zr, they demonstrated enhanced reactivity and high CO tolerance, having the advantage of reducing the cost of the catalyst, potentially substituting expensive platinum group metals by more affordable components.
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Delormel, Tiffany. « Étude du rôle de CPK5 et CPK6 dans les voies de signalisation de stress via l’identification de leurs substrats chez Arabidopsis thaliana ». Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS536.

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Dans leur environnement naturel, les plantes doivent continuellement s’adapter pour survivre aux diverses stimuli auxquels elles sont confrontées. La salinité est responsable de fortes pertes de rendements et une meilleure compréhension des mécanismes capables d’induire la tolérance de la plante est nécessaire. Au niveau cellulaire, les stress biotique et abiotique perçus induisent la production de messagers secondaires ce qui active des voies de signalisation faisant intervenir différentes familles de protéines kinases dont les protéines kinases dépendantes du calcium, les CDPKs. Lorsqu’elles sont activées, elles vont phosphoryler des substrats permettant la mise en place des réponses spécifiques au stress perçu.CPK5 et CPK6 sont des régulateurs positifs de la tolérance au stress salin et également de la résistance aux bactéries, notamment par l’induction de gènes de réponses. L’identification de 25 nouveaux substrats putatifs par une approche phosphoprotéomique pourraient permettre une meilleure compréhension du rôle de CPK5 et CPK6 dans la réponse aux stress. Parmi les candidats étudiés dans ce manuscrit, six ont été validées in vitro, notamment deux ubiquitine ligases E3 dont la mutation d’un site conservé inhibe la phosphorylation par CPK5 et CPK6. Bien que l’étude des mutants knock-out n’ait pas permis de leur attribuer un rôle dans la tolérance à la salinité, certains pourraient agir en aval de CPK5/6 dans la réponse aux pathogènes
Plants are subjected to several environmental stimuli and must adapt to survive. A better understanding of the mechanisms involved in plant tolerance is necessary to find solution to the salt stress that is responsible for important yield loss. At the cellular level, the perception of biotic and abiotic stress leads to the accumulation of secondary messengers that activate protein kinases involved in different signaling pathways as calcium-dependent protein kinases (CDPKs). Once they are activated, CDPKs can phosphorylate substrates which are able to induce appropriate responses to the stimuli.CPK5 and CPK6 are positive regulators of salt stress and biotic stress, notably through the induction of response genes. To better understand their roles in plant stress response, a phosphoproteomic approach was conducted and could identify 25 new putative substrates for CPK5. Six of the studied candidates were validated in vitro for phosphorylation by CPK5 and CPK6. Among them, two ubiquitin E3 ligases are not phosphorylated anymore by CPK5 and CPK6 when mutated on a conserved phosphosite. Unfortunately, the knock-out mutants of the substrates in salt condition did not show any phenotype. However some of them are known to play a role in response to pathogen and could act downstream of CPK5 and CPK6
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Slowik, Daria Marta [Verfasser], et Wolfram [Akademischer Betreuer] Saenger. « Structural and Functional Investigations on the Photosystem II core subunit PsbO and the antenna pigment-protein complex CP29 / Daria Marta Slowik. Betreuer : Wolfram Saenger ». Berlin : Universitätsbibliothek der Technischen Universität Berlin, 2012. http://d-nb.info/1024771938/34.

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Velásquez, Angela Maria Arenas. « Do screening ao mecanismo de ação, uma contribuição para a descoberta de ciclopaladados bioativos : a atividade leishmanicida de CP2 e seu efeito inibitório frente à DNA topoisomerase 1B de Leishmania / ». Araraquara, 2017. http://hdl.handle.net/11449/150125.

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Orientadora: Marcia Aparecida Silva Graminha
Banca: Adelino Vieira de Godoy Netto
Banca: Luiz Ricardo Orsini Tosi
Banca: Pio Colepicolo Neto
Banca: Silvia Reni Bortolin Uliana
Resumo: As leishmanioses são doenças mundialmente distribuídas, encontradas nas áreas tropicais e subtropicais do mundo e que são caudas por protozoários parasitos do gênero Leishmania spp. A pesar dos inúmeros problemas associados aos tratamentos disponíveis (como alta toxicidade dos fármacos, limitada eficácia e casos de resistência haverem surgido), ainda estás doenças são negligenciadas pelas industrias farmacêuticas e pelos governos. Na procura por novos fármacos com amplo espectro de ação e baixa toxicidade, há evidências que sugerem que complexos de metais de transição podem atuar em diversos compartimentos ou organelas dos protozoários, além de apresentar baixa toxicidade no hospedeiro mamífero. No presente trabalho, realizou-se a avaliação leishmanicida in vitro de seis compostos ciclopaladados, [Pd(dmba)(µ-Cl)]2 (CP1), [Pd(dmba)(µ-N3)]2 (CP2), [Pd(dmba)(µ-NCO)]2 (CP3), [Pd(dmba)Cl(isn)] (CP4), [Pd(dmba)(N3)(isn)] (CP5) e [Pd(dmba)(NCO)(isn)] (CP6) e seus correspondentes ligantes livres, Hdmba: N,N-dimetilbenzilamina e isn: isonicotinamida. O composto CP2 inibiou o crescimento das formas promastigotas de Leishmania amazonensis (IC50 = 13,2 ± 0,7 µM), reduz a proliferação das formas amastigotas intracelulares (IC50 = 10,2 ± 2,2 µM) e apresentou um baixo efeito citotóxico frente a macrófagos peritoneais (CC50 = 506,0 ± 10,7 µM). Dados in vitro da atividade anti-T. cruzi e anti-T. brucei, parasitos causadores das doenças de Chagas e do sono, respectivamente, também demonstraram que os compostos ciclopaladados apresentam amplo espectro de ação constituindo-se em excelentes candidatos para o tratamento das doenças negligenciadas em estudo. O composto CP2 apresentou-se para as formas amastigotas intracelulares de L. amazonensis pelo menos 50 vezes mais seletivo e 200 vezes mais seletivo para as amastigotas de T. cruzi vs. células de mamífero...
Abstract: Leishmaniasis are diseases globally distributed in tropical and subtropical areas of the world and Leishmania spp. are the etiological agents of the diseases. Numerous problems associated with available treatments of the disease are still unsatisfactory because currently available drugs are highly toxic, little effectiveness and drug resistance cases have emerged. Furthermore, leishmaniasis are a neglected disease by pharmaceutical industries and governments. In the search for new drugs with a broad spectrum of action and low toxicity, there is evidence to suggest that transition metal complexes can act in several compartments or organelles of protozoa, as well as to present low toxicity in the mammalian host. In this work, we evaluated the leishmanicidal and trypanocidal in vitro activity of six cyclopalladated compounds: [Pd(dmba)(µ-Cl)]2 (CP1), [Pd(dmba)(µ-N3)]2 (CP2), [Pd(dmba)(µ-NCO)]2 (CP3), [Pd(dmba)Cl(isn)] (CP4), [Pd(dmba)(N3)(isn)] (CP5), [Pd(dmba)(NCO)(isn)] (CP6) and the free ligands, Hdmba: N,N- dimethylbenzylamine e isn: isonicotinamide. The cyclopalladated complexes CP2 inhibited the growth of the promastigote forms of Leishmania amazonensis (IC50 = 13,2 ± 0,7 µM), reduced the proliferation of intracellular amastigote forms (IC50 = 10,2 ± 2,2 µM) and showed a low cytotoxic effect against peritoneal macrophages (CC50 = 506,0 ± 10,7 µM). In vitro assays against T. cruzi and T. brucei, parasites that cause Chagas disease and sleeping sickness, respectively, demons... (Resumo completo, clicar acesso eletrônico abaixo)
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Iseri, Erkut Inan. « Exciton Simulations Of The Optical Properties Of Several Photosynthetic Light-harvesting Complexes ». Phd thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/3/12605040/index.pdf.

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The work presented in this thesis was aimed to investigate the structure-function relationship of several photosynthetic Light-Harvesting Complexes (LHCs) including Chlorophyll Protein 29 (CP29) and Light-Harvesting Complex II (LHCII) of green plants, and Fenna-Matthews-Olson (FMO) complex of green sulfur bacterium Chlorobium tepidum. Based on the exciton calculations, a model was proposed to the electronic excited states (EES) of both CP29 and LHCII complexes by incorporating a considerable part of the current information offered by structure determination, mutagenesis analysis and spectroscopy in the modeling. The essential parameters for characterizing the excited states, Qy dipole orientations and site energies were assigned by suggesting a model that can explain both the key features of the linear (polarized) absorption spectra and the time scales of the energy transfer processes in CP29 and LHCII. The idea of offering structural information through setting connection between the spectroscopy and the spectral simulations were supported by the presented results on CP29 and LHCII. New spectroscopic measurements (absorption, linear dichroism (LD) and circular dichroism), carried out at 4 K on the FMO complex were presented, and also the LD spectrum was corrected for the degree of orientation of the sample, in order to provide comparison of not only the shape but also the size of the simulated and experimental spectra. The EES structure of the FMO complex was studied by simulating the measured optical spectra with more realistic model than the previously applied models. Simulations have been carried out with a computer program based on exciton model, which includes inhomogeneous, homogeneous and lifetime broadenings explicitly.
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Palacios, Leon Julia Isabel. « La planificación de las estrategias de expresión oral favorece la lectoescritura en el logro de los aprendizajes de los estudiantes de 3 a 5 años de la Institución Educativa N°040- CP2 Colera-Tambogrande ». Bachelor's thesis, Pontificia Universidad Católica del Perú, 2018. http://tesis.pucp.edu.pe/repositorio/handle/123456789/10805.

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El presente plan de acción busca fortalecer a los docentes en la planificación de estrategias de expresión oral que los lleve a lograr en los estudiantes la lectoescritura al nivel de su desarrollo, es evidente el impacto negativo que causa la inadecuada planificación de los aprendizajes, ya que se trabaja con estrategias tradicionales. Los docentes carecían de un trabajo colegiado, lo que no les permitía compartir y reflexionar de las experiencias que cada una de ellas planteaba en el desarrollo de sus estrategias con los estudiantes en el aula. Los objetivos de la investigación apuntan a implementar un sistema de estrategias para el desarrollo de la expresión oral en los estudiantes, desarrollar un trabajo colaborativo con las docentes en la planificación de los proyectos que busque el descubrimiento de la lectoescritura en los estudiantes y buscar la metodología que permita superar las deficiencias en la planificación de las sesiones de aprendizaje. Emilia Ferreiro en su aporte afirma que el niño diferencia el dibujo de la escritura comienza a representar por escrito lo que quiere comunicar, empleando al principio signos arbitrarios; a medida que se apropia del código escrito convencional su escritura cambia hasta emplear las letras del alfabeto. Estas formas sucesivas de representación escrita se denominan los niveles de construcción de la escritura. Estos niveles son: Pre silábico, silábico, silábico–alfabético y alfabético. Llegando a la conclusión que los estudiantes de preescolar tienen que ir descubriendo y apoderarse del mundo escrito con naturalidad, en forma libre y a través del método lúdico, respetando su desarrollo.
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Nguyen, Thi D. T. « Antilarval substituted phenols, distribution of tricyclic pyrones in mice, and synthesis of unnatural amino acids ». Diss., Kansas State University, 2014. http://hdl.handle.net/2097/18199.

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Doctor of Philosophy
Department of Chemistry
Duy H. Hua
Three research projects were carried out and they are described below. The synthesis of substituted phenolic compounds including halogenated di- and trihydroxybenzenes, aminophenols, and substituted di-tert-butylphenols are described. Redox potentials of the synthesized molecules along with various known laccase substrates were measured, and an inverse relationship between the oxidation potential and the efficiency of oxidation by laccase of halogenated hydroxybenzenes and aminophenols is demonstrated. The synthesized substituted phenols were found to be substrates but not inhibitors of laccase. We discovered a new class of di-tert-butylphenols compounds that inhibits the growth of mosquito larvae at low concentrations. Compound 17, 2,4-di-tert-butyl-6-(3-methyl-2-butenyl) phenol caused greater than 98% mortality of third-instar larvae of Anopheles gambiae in the concentration of 0.18 µM. These compounds do not inhibit laccases. It appears that they affect a new target of the mosquito that is different from those of currently existing pesticides. Two anti-Alzheimer molecules, CP2 and TP70, discovered in our laboratory were studied for their pharmacokinetics and distribution. The distribution of CP2 and TP70 in mouse brain region and various tissues of mice were examined. HPLC analysis revealed that CP2 treatment in primary neurons accumulates in mitochondria fraction. Similarly, the amount of CP2 in the brain tissue from wild type and APP/PS1 mice treated with 25 mg/kg/daily for 2 months also have the highest concentration in the mitochondria fractions in the hippocampus. The results show that CP2 and TP70 can penetrate the blood brain barrier and accumulate in the tissue in significant amounts. Pharmacokinetics and bioavailability of compound TP70 were determined. Area under the curve and bioavailability value F were calculated, and data show that TP70 has a good PK profile and bioavailability. For the preparation of a novel tripeptidyl norovirus 3C-like protease (3CL[superscript]pro) inhibitor, the P3 unnatural amino acid, (S)-3-hydroxyphenylalanine was synthesized. The P3 is designed to increase the polarity with the addition of the alcohol group. After combining the P3 unnatural amino acid with the P1 and P2 to form the novel tripeptidyl compound, a study comparing the relations between the structure and its activity (SAR) will confirm whether prediction is correct in our pursuit for an antiviral therapeutic drug in the form of a protease inhibitor.
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Tu, Xiao. « Measurement of long-range correlations in small systems with the ATLAS detector ». Thesis, 2020. https://doi.org/10.7916/d8-cp2w-ge73.

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Two-charged-particle correlations are measured as a function of pseudorapidity and azimuthal angle difference in pp collisions at √s = 13, 2.76 and 5.02 TeV with the ATLAS detector at the Large Hadron Collider. A long-range structure in the two-dimensional function centered at ∆φ = 0 and extending over a large range of ∆η referred to as the “ridge” is seen in the three data sets. A template fitting method is implemented to extract the Fourier harmonics of the flow and gives the dependence of the harmonics on the charged-particle multiplicities. In this method a rescaled correlation function from peripheral events representing the recoil component plus a cosine modulation representing the ridge is used to describe the whole one-dimensional correlation function. Different multiplicity intervals for the peripheral events are used to extract the harmonics. The results presented show that vn,n from correlation functions can be factorized into the products of single particle vn. Significant contributions from v₂, v₃ and v₄ are obtained and their dependences on multiplicity and transverse momentum are studied. It is also shown that there is significant vn even in the lowest multiplicity bins. In addition, the second harmonics v₂ in pp do not have a significant dependence on both the multiplicity and collision energy. Results of pp and pPb at the same energy are compared with each other in both multiplicity and pT distributions. Both chᵗʳᵏ−chᵗʳᵏ and chᵗʳᵏ-muon correlations are measured in pPb collisions at √sNN = 8.16 TeV. Long-range correlations are studied through template fitting procedure. chᵗʳᵏ-v₂ increases with the number of reconstructed charged tracks at low multiplicity and saturates at high multiplicity. Muon-v₂ is considerably smaller than chᵗʳᵏ-v₂ and only has a weak dependence on event multiplicity. Factorization in both cases works pretty well. Two-charged-particle correlation functions are also measured in Xe+Xe events at √sNN = 5.44 TeV. In the most central collisions direct Fourier decomposition is preferred to avoid negative recoil component that might appear in the template fitting method. vn reaches its maximum value in the mid-centrality region and becomes smaller at both low and high centralities. Results are compared with Pb+Pb events at √sNN = 5.02 TeV showing that vn obtained from these two systems have similar values and behaviors.
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Livres sur le sujet "CP26"

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Authority, Financial Services. High level standards for firms and indiviiduals : Issues arising out of CP35 and CP26. London : Financial Services Authority, 2000.

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Freuder, Eugene C., dir. Principles and Practice of Constraint Programming — CP96. Berlin, Heidelberg : Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/3-540-61551-2.

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CP96 (1996 Cambridge, Mass.). Principles and practice of constraint programming--CP96 : Second international conference, CP96, Cambridge, MA, USA, August 19-22, 1996 : proceedings. Berlin : Springer, 1996.

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United States. Federal Energy Regulatory Commission. Office of Energy Projects. et United States Coast Guard, dir. Final environmental impact statement, Broadwater LNG project, Broadwater Energy LLC and Broadwater Pipeline LLC, docket nos. PF05-4, CP06-54-000, and CP06-55-000. Washington, D.C : Federal Energy Regulatory Commission, Office of Energy Projects, 2006.

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United States. Federal Energy Regulatory Commission. Office of Energy Projects. et United States Coast Guard, dir. Draft environmental impact statement, Broadwater LNG project, Broadwater Energy LLC and Broadwater Pipeline LLC, docket nos. PF05-4, CP06-54-000, and CP06-55-000. Washington, D.C : Federal Energy Regulatory Commission, Office of Energy Projects, 2006.

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Projects, United States Federal Energy Regulatory Commission Office of Energy. Phoenix Expansion Project : Draft environmental impact statement : Transwestern Pipeline Company, LLC : docket no. CP06-459-000. Washington, DC : Federal Energy Regulatory Commission, 2007.

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Projects, United States Federal Energy Regulatory Commission Office of Energy. Phoenix Expansion Project : final environmental impact statement : Transwestern Pipeline Company, LLC : docket no. CP06-459-000. Washington, DC : Federal Energy Regulatory Commission, Office of Energy Projects, 2007.

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Authority, Financial Services. Feedback Statement to CP56 and Second Consultation Paper on the FSA's Post-N2 Fee-raising Arrangements. London : Financial Services Authority, 2000.

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Jean-Paul, Montagnier, et Madin Henri 1698-1748, dir. Traités du contrepoint simple : facsimilés des exemplaires 8p0s Cp2s 186 (1739) et Vmp8s de la Bibliothèque nationale de France. Paris : Société française de musicologie, 2004.

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Sophocles. Ajax (cp56). Belles Lettres, 2001.

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Chapitres de livres sur le sujet "CP26"

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Rigoni, Fernanda, Roberto Bassi et Giorgio M. Giacometti. « Spectroscopic Characterization of Purified Chlorophyll a/b Protiens CP29, CP26, CP24 from Maize PSII Antenna Complex ». Dans Techniques and New Developments in Photosynthesis Research, 141–44. Boston, MA : Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-8571-4_16.

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Dainese, P., M. L. Di Paolo, M. Silvestri et R. Bassi. « Properties of the Minor Chlorophyll a/b Proteins CP29, CP26 and CP24 from Zea mays Photosystem II Membranes ». Dans Current Research in Photosynthesis, 1209–12. Dordrecht : Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0511-5_279.

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Dainese, P., E. Bergantino, S. Sechi, R. Bassi et E. Pichersky. « cDNA Deduced Amino Acid Sequences of Maize CP24 and CP26, the Two Major Zeaxanthin-Binding Proteins of Photosystem II ». Dans Photosynthesis : from Light to Biosphere, 199–202. Dordrecht : Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-009-0173-5_45.

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Minagawa, Jun, Kab-Cho Han, Naoshi Dohmae, Koji Takio et Yorinao Inoue. « Cloning and Characterization of a Cdna for Algal Homologue of CP26 in the Light-Harvesting Complex II of Chlamydomonas Reinhardtii ». Dans Photosynthesis : Mechanisms and Effects, 381–84. Dordrecht : Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-3953-3_90.

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Giuffra, E., D. Cugini, A. Pagano, R. Croce, D. Sandonà et R. Bassi. « In Vitro Reconstitution and Pigment Binding Properties of Recombinant CP29 and CP24 ». Dans Photosynthesis : from Light to Biosphere, 271–74. Dordrecht : Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-009-0173-5_63.

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Weiss, Werner W. « Rapid Oscillations of CP2-Stars ». Dans Upper Main Sequence Stars with Anomalous Abundances, 219–33. Dordrecht : Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4714-6_37.

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Song, Jian. « The Kähler–Ricci Flow on CP2 ». Dans Geometric Analysis, 465–69. Cham : Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-34953-0_18.

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Pardasani, R. T., et P. Pardasani. « Weiss constant of [Cp2*Fe]•+ [TCNE]•− ». Dans Magnetic Properties of Paramagnetic Compounds, 2274. Berlin, Heidelberg : Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-23675-4_2023.

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Pardasani, R. T., et P. Pardasani. « Magnetic properties of [Cp2*Fe]•+ [TCNQMeCl]•− ». Dans Magnetic Properties of Paramagnetic Compounds, 2290. Berlin, Heidelberg : Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-23675-4_2032.

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Pardasani, R. T., et P. Pardasani. « Magnetic properties of [Cp2*Fe]•+ [TCNQMe2]•− ». Dans Magnetic Properties of Paramagnetic Compounds, 2284–85. Berlin, Heidelberg : Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-23675-4_2029.

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Actes de conférences sur le sujet "CP26"

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Miic, Marko, Iain Bethune et Milo Tomaevic. « Automated Multi-platform Testing and Code Coverage Analysis of the CP2K Application ». Dans 2014 IEEE Seventh International Conference on Software Testing, Verification and Validation (ICST). IEEE, 2014. http://dx.doi.org/10.1109/icst.2014.21.

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Ginsberg, Naomi S., Jeffrey A. Davis, Matteo Ballottari, Yuan-Chung Cheng, Roberto Bassi et Graham R. Fleming. « Determining Chlorophyll Orientation in the CP29 Light Harvesting Complex with Arithmetic Polarized 2D Electronic Spectroscopy ». Dans International Conference on Ultrafast Phenomena. Washington, D.C. : OSA, 2010. http://dx.doi.org/10.1364/up.2010.the5.

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Lass, Michael, Robert Schade, Thomas D. Kuhne et Christian Plessl. « A Submatrix-Based Method for Approximate Matrix Function Evaluation in the Quantum Chemistry Code CP2K ». Dans SC20 : International Conference for High Performance Computing, Networking, Storage and Analysis. IEEE, 2020. http://dx.doi.org/10.1109/sc41405.2020.00084.

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Łapiński, A., R. Świetlik, I. Olejniczak, D. Łazarski, M. Fourmigué, E. W. Reinheimer, O. Jeannin, K. Yakushi, P. M. Champion et L. D. Ziegler. « Flexibility of Paramagnetic (d[sup 1]) Organometallic Dithiolene Complexes [Cp2M(dmit)][sup +⋅] (M = Mo, W) Studied by Raman Spectroscopy ». Dans XXII INTERNATIONAL CONFERENCE ON RAMAN SPECTROSCOPY. AIP, 2010. http://dx.doi.org/10.1063/1.3482836.

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Wang, David H., J. David Jacobs, Aaron Trionfi, Michael J. Arlen, Julia W. P. Hsu, Richard A. Vaia et Loon-Seng Tan. « In-situ synthesis and thermal-electrical properties of CP2- polyimide/pristine and amine-functionalized carbon nanofiber composites ». Dans Second International Conference on Smart Materials and Nanotechnology in Engineering, sous la direction de Jinsong Leng, Anand K. Asundi et Wolfgang Ecke. SPIE, 2009. http://dx.doi.org/10.1117/12.839929.

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Ogneva, Z. V., O. A. Aleinova, A. R. Suprun, A. A. Ananyev, A. S. Dubrovina et K. V. Kiselev. « Expression of spliced mRNA variants of calcium-dependent protein kinases CPK21 and CPK26 genes in Amur grape VitisamurensisRupr. under the influence of abiotic stress ». Dans IX Congress of society physiologists of plants of Russia "Plant physiology is the basis for creating plants of the future". Kazan University Press, 2019. http://dx.doi.org/10.26907/978-5-00130-204-9-2019-320.

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M., Werkl, et Heck D. « Coping with Incompleteness : An Approach using Time and Production Related Compensation ». Dans Modern Methods and Advances in Structural Engineering and Construction. Singapore : Research Publishing Services, 2011. http://dx.doi.org/10.3850/978-981-08-7920-4_s1-cp06-cd.

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Jung, Wooyong, Seung-Heon Han, Yong-Woo Kim et Jaechul Choi. « Is it True that High Risk Yields High Returns in International Construction Projects ? » Dans Modern Methods and Advances in Structural Engineering and Construction. Singapore : Research Publishing Services, 2011. http://dx.doi.org/10.3850/978-981-08-7920-4_s1-cp16-cd.

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Moazzami, Mohammad, Reza Dehghan et Y. Janaka Ruwanpura. « Appropriate Contracting Strategy for Fast-Track Projects ». Dans Modern Methods and Advances in Structural Engineering and Construction. Singapore : Research Publishing Services, 2011. http://dx.doi.org/10.3850/978-981-08-7920-4_s1-cp20-cd.

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KovaČec, Sašo, Igor Pšunder et Marko Soršak. « Model of Economic Justification of Substitutional Construction ». Dans Modern Methods and Advances in Structural Engineering and Construction. Singapore : Research Publishing Services, 2011. http://dx.doi.org/10.3850/978-981-08-7920-4_s1-cp21-cd.

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Rapports d'organisations sur le sujet "CP26"

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Mullin, Jonathan. Trace Conserving Purification for Linear Scaling [O(N)] Methods : A First Enhancement to CP2K. Fort Belvoir, VA : Defense Technical Information Center, septembre 2014. http://dx.doi.org/10.21236/ada610219.

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Veilleux, Richard E., Jossi Hillel, A. Raymond Miller et David Levy. Molecular Analysis by SSR of Genes Associated with Alkaloid Synthesis in a Segregating Monoploid Potato Family. United States Department of Agriculture, mai 1994. http://dx.doi.org/10.32747/1994.7570550.bard.

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More than 15,000 anthers of an interspecific hybrid (CP2) between two diploid (2n=2x=24) potato species, Solanum chacoense (weedy) and S. phureja (cultivated), were cultured to generate a family of monoploid (haploid, 2n-1x=12) plants. Of 260 regenerated plants, 34 were monoploid, 210 diploid and 16 tetraploid. SSR analysis revealed that six monoploids were genetically identical and 14 diploids were homozygous, thus limiting the population to 42 (28 monoploids and 14 homozygous diploids). New microsatellite loci were developed for potato from database sequences (15), a conventional genomic library (6), an enriched library (18) and tomato (11). Of these, 13 were polymorphic in the CP2 family and 11 were used to study genetic segregatin. Four of 11 exhibited skewed segregation in the monoploid family. Seven of 18 microsatellite markers were polymorphic and informative on a set of 12 tetraploid potato cultivars. Acetylleptinidine (ALD) is the aglycone of leptines, a natural defense against insects, especially the highly destructuve Colorado potato beetle. ALD is absend in S. phureja but highly expressed in the S. chacoense parent of CP2. A backcross population between CP2 and tis S. phureja parent was used to examine segregation for ALD. Bulks of 10 backcross individuals that expressed ALD and 10 that did not were used to identify putative RAPD markers associatd with the trait. Of 80 primers tested, one putative marker amplified by OPQ02 was present in eight of ten individuals comprising the high bulk and absent in all 10 individuals comprising the low bulk. This is a putative marker for ALD expression in potato.
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Alex J. Dragt. Final Technical Report for the Grant DF-FG02-03ER41236 Partial Support of CPO6, The Sixth International Charged-Particle Optics Conference. Office of Scientific and Technical Information (OSTI), juin 2004. http://dx.doi.org/10.2172/824990.

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