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1

Kumar, Sanjeev, R. Bansal, A. Khare, KPS Malik, VK Malik, K. Jain et C. Jain. « Conjunctival impression cytology in computer users ». Nepalese Journal of Ophthalmology 5, no 1 (25 mars 2013) : 33–37. http://dx.doi.org/10.3126/nepjoph.v5i1.7819.

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Introduction:It is known that the computer users develop the features of dry eye. Objective: To study the cytological changes in the conjunctiva using conjunctival impression cytology in computer users and a control group. Materials and methods: Fifteen eyes of computer users who had used computers for more than one year and ten eyes of an age-and-sex matched control group (those who had not used computers) were studied by conjunctival impression cytology. Results: Conjunctival impression cytology (CIC) results in the control group were of stage 0 and stage I while the computer user group showed CIC results between stages II to stage IV. Among the computer users, the majority ( > 90 %) showed stage III and stage IV changes. Conclusion: We found that those who used computers daily for long hours developed more CIC changes than those who worked at the computer for a shorter daily duration. Nepal J Ophthalmol 2013; 5(9):33-37 DOI: http://dx.doi.org/10.3126/nepjoph.v5i1.7819
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Chowdhury, Swapan, Rajesh Kumar, N. K. Ganguly, Lata Kumar, C. K. Nain et B. N. S. Walia. « Conjunctival impression cytology with transfer (CICT) to detect pre-clinical vitamin A deficiency among slum children in India ». British Journal of Nutrition 75, no 5 (mai 1996) : 785–90. http://dx.doi.org/10.1079/bjn19960182.

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In order to establish a method usable in the field for diagnosis of pre-clinical vitamin A deficiency, conjunctival impression cytology with transfer (CICT) was used in 200normal slum children aged 6−120 months in Chandigarh, India. Conjunctival impressions taken on cellulose acetate paper were transferred to glass slides which were fixed in ethanol and stained with alcian blue and carbol fuchsin. Sixty samples of cellulose acetate paper were preserved after transfer of impression and were stained later. Transfer was complete in forty-eight samples and in the other twelve it was incomplete. Conjunctival impressions on paper and slide of these twelve cases were comparable. At a plasma retinol concentration of <0·70 pmol/l measured by HPLC the sensitivity, specificity and positive predictive values of CICT were 90·5%, 100% and 100% respectively. Compared with conventional conjunctival impression cytology, CICT is less time consuming, cheaper and comparable in validity. It is thus more suitable than the conventional method for mass screening
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Sapkota, K. « Conjunctival impression cytology ». Nepalese Journal of Ophthalmology 5, no 2 (25 septembre 2013) : 284–85. http://dx.doi.org/10.3126/nepjoph.v5i2.8747.

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Chaidaroon, Winai, Chutikarn Dejkriengkraikul, Sirawit Isipradit et Nirush Lertprasertsuke. « Conjunctival Intraepithelial Neoplasia in a Patient Presenting with Pigmented Conjunctival Lesion ». Case Reports in Ophthalmology 12, no 1 (21 janvier 2021) : 77–82. http://dx.doi.org/10.1159/000510570.

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We report a case of conjunctival intraepithelial neoplasia (CIN) in a patient presenting with the pigmented conjunctival lesion.<b><i></i></b>This study involved a 56-year-old woman that presented with right eye irritation for 1 month. She noticed brownish pigmentation arising from her right nasal conjunctiva and growing slowly over time. Biomicroscopic examination showed a gelatinous pigmented conjunctival mass with feeder vessels. Conjunctival impression cytology (CIC) was done and reported as CIN. Treatment was started with 0.02% mitomycin-C eye drops. The conjunctival lesion responded well to medication. This report shows that CIN can manifest as a pigmented tumor, resembling melanoma. CIC plays a role in the diagnosis of this condition. This tumor responded well with 0.02% mitomycin-C eye drops.
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Citirik, Mehmet, Canan Altunkaya, Dilek Soba, Tolga Bicer et Huseyin Ustun. « Comparison of Conjunctival Cytological Alterations following Conventional and Sutureless Sclerotomies ». Ophthalmologica 233, no 3-4 (2015) : 230–35. http://dx.doi.org/10.1159/000371771.

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Purpose: To assess the alterations in conjunctival impression cytology following 23-gauge transconjunctival sutureless versus conventional pars plana vitrectomy. Patients and Methods: Sixty consecutive patients were enrolled in the study. Conjunctival impression cytology was performed on 30 eyes (of 30 subjects) with 23-gauge transconjunctival sutureless vitrectomy and on 30 eyes (of 30 subjects) with conventional vitrectomy. Conjunctival impression cytology was performed preoperatively on the 1st day and in the 3rd month after the surgery. Impression cytology specimens of each group were graded and scored using a range of 0-3 according to Nelson's method. Results: In the conventional pars plana vitrectomy group, statistically significant alterations in the conjunctival impression cytology were detected on the 1st postoperative day (p = 0.001) and in the 3rd postoperative month (p = 0.001), whereas in the 23-gauge transconjunctival sutureless pars plana vitrectomy group, statistically significant changes were observed on the 1st postoperative day. However, no significant changes were observed in the following 3 postoperative months (p = 0.08). Conclusion: The properties of impression cytology were altered in the early postoperative period after sutureless and conventional vitrectomy. These changes were improved in the sutureless vitrectomy group only. Sutureless vitrectomy also had an advantageous effect on the conjunctival cytological changes and conjunctival structure.
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Yafawi, Rolla, Frederick Sace, Jing-Feng Huang et Annette John-Baptiste. « Assay development and validation of inflammatory markers in impression cytology specimens (144.19) ». Journal of Immunology 184, no 1_Supplement (1 avril 2010) : 144.19. http://dx.doi.org/10.4049/jimmunol.184.supp.144.19.

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Abstract The principle of Impression Cytology (IC) utilizes a non-invasive technique to remove superficial layers of the ocular surface. The application of a filter to the surface of the bulbar conjunctiva allows for repeated collection of superficial cells for the analysis of ocular surface disorders. Evidence suggests expression of the HLA-DR antigen on the surface of conjunctival epithelial cells is associated with allergic conjunctivitis and dry eye syndrome. Performance characteristics of HLA-DR was evaluated through intra, inter and stability assays. Evaluation of the reproducibility and overall performance of the novel methodology would be useful in understanding the tolerance level of the assay. Utilizing established techniques, IC specimens were obtained from 12 donors and assayed over multiple days and timepoints. Conjunctival epithelial cells were extracted and assayed based on differential immunostaining of both conjunctival epithelial cells and leukocytes. The reproducibility across donors over time was consistent, demonstrating conjunctival cells maintained their integrity of cell surface expression of HLA-DR. In conclusion, the studies met all validation criteria, and support the utilization of HLA-DR inflammatory measurements in impression cytology specimens. Utilization of a flow cytometric platform to examine the expression of HLA-DR antigen may help predict clinical outcome, evaluate disease progression, and monitor the effects of treatment.
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Ng, Guan Fook, Ishak Siti Raihan, Yaakub Azhany, Che Hussin Che Maraina, K. Gurusamy Banumathi et Tajudin Liza-Sharmini. « Conjunctival TGF-B Level in Primary Augmented Trabeculectomy ». Open Ophthalmology Journal 9, no 1 (31 juillet 2015) : 136–44. http://dx.doi.org/10.2174/1874364101509010136.

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Purpose : To compare the levels of conjunctival transforming growth factor beta (TGF-β) between glaucoma and control patients and to determine conjunctival TGF-β levels before and 3 months after augmented primary trabeculectomy. Methods : Patients with primary open angle glaucoma (POAG) or primary angle closure glaucoma (PACG) admitted for mitomycin (MMC) augmented primary trabeculectomy due to failure in achieving target pressure after maximum medical therapy were selected. Age-matched non-glaucoma patients were controls. Impression cytology of the conjunctiva was obtained twice from glaucoma patients (1 week before augmented primary trabeculectomy and 3 months after surgery) and once from controls. Conjunctival cells were tagged with an anti-TGF-β antibody and analyzed by flow cytometry. Results : Eighteen patients (11 POAG and 7 PACG patients) and 18 age-matched control patients were included. Conjunctival TGF-β levels were significantly different between glaucoma (35.21% ± 14.12%) and control patients (14.96% ± 6.34%) (p = 0.001). There was a significant reduction in conjunctival TGF-β levels after augmented trabeculectomy (23.0% ± 13.8%) (p < 0.001). A significantly greater reduction in conjunctival TGF-β levels (61.6% ± 17.9%) was associated with complete success of trabeculectomy at 3 months (83.3%) after surgical intervention (p = 0.029). Conclusion : The reduction of TGF-β on the conjunctival post primary augmented trabeculectomy may suggest TGF-β as potential predicting marker of short term trabeculectomy success. However, the result may be affected by site of impression, topical pressure lowering drugs and small sample size.
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Martinez, Alberto J., Mathew B. Mills, Karen B. Jaceldo, Fermin O. Tio, Ikaehota B. Aigbivbalu, Susan B. Hilsenbeck et Richard W. Yee. « Standardization of Conjunctival Impression Cytology ». Cornea 14, no 5 (septembre 1995) : 515???522. http://dx.doi.org/10.1097/00003226-199509000-00012.

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Bolzan, Aline A., Adriana T. J. Brunelli, Marcio B. Castro, Marcos A. Souza, Jose L. Souza et Jose L. Laus. « Conjunctival impression cytology in dogs ». Veterinary Ophthalmology 8, no 6 (novembre 2005) : 401–5. http://dx.doi.org/10.1111/j.1463-5224.2005.00414.x.

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Anshu, Nitin Gangane, V. R. Venkataramanan et Vidyadhar M. Patil. « Conjunctival impression cytology in trachoma ». Diagnostic Cytopathology 37, no 3 (mars 2009) : 170–73. http://dx.doi.org/10.1002/dc.20980.

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Keijser, S., G. S. Missotten, D. De Wolff-Rouendaal, S. L. J. Verbeke, C. M. Van Luijk, M. Veselic-Charvat et R. J. W. De Keizer. « Impression Cytology of Melanocytic Conjunctival Tumors Using the Biopore Membrane ». European Journal of Ophthalmology 17, no 4 (juillet 2007) : 501–6. http://dx.doi.org/10.1177/112067210701700404.

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Purpose To compare a new Biopore membrane impression cytology method with the routinely used exfoliative cytology in patients with a melanocytic lesion of the conjunctiva. Methods Sixty-eight consecutive patients with a conjunctival melanocytic lesion underwent Biopore membrane impression cytology as well as exfoliative cytology. A histologic sample was also available in 26 cases. All Biopore samples were stained immediately with RAL 555. Both Biopore and exfoliative cytology samples were assessed by two cytopathologists and graded into four different categories of atypia. Results Twenty-three out of 26 Biopores and 20 out of 24 for the exfoliative smears correlated with the corresponding histologic sample. Biopore cytology resulted in higher numbers of cells with a greater density compared to exfoliative cytology. Conclusions Biopore cytology can be used for cytologic sampling of conjunctival melanocytic lesions. Because of the larger amount and higher density of cells obtained with the Biopore membrane, interpretation by a pathologist is easier and faster. Sampling of the fornix, caruncula, and ocular material in children is difficult with the Biopore method, and exfoliative cytology seems to be the favorable test in those situations.
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Rodríguez Feijoo, D., I. Romero Moreno, C. López Gutierrez, M. Usabiaga Usandizaga, M. Cisneros Carpio, A. Amias Gorostiza et J. Alberdi Alberdi. « Conjunctival keratoacanthoma. Diagnosis, treatment and monitoring by conjunctival impression cytology ». Archivos de la Sociedad Española de Oftalmología (English Edition) 87, no 3 (mars 2012) : 82–85. http://dx.doi.org/10.1016/j.oftale.2012.05.012.

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Rivas, L., M. A. Oroza, A. I. Sanz, Z. Chen, O. Shalaby et J. Murube. « The Association of Conjunctival Snake-Like Chromatin with Keratoconjunctivitis Sicca ». European Journal of Ophthalmology 8, no 4 (octobre 1998) : 217–23. http://dx.doi.org/10.1177/112067219800800403.

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Purpose This work describes the snake-like chromatin cells in the conjunctiva of patients with keratoconjunctivitis sicca (KCS), assessing the relationship between tear function parameters and the severity of the disease, and searching for any differential pattern that could lead to early and diagnosis help clarify the etiology of KCS. Methods The conjunctiva of 366 eyes from 187 patients with KCS, and 30 eyes from 15 controls, were classified according to the results of the Schirmer I test, break-up time, rose Bengal staining, osmolarity, ferning tests and electrophoresis; they were then studied by impression cytology and electron microscopy. Results Snake-like chromatin cells, other nuclear changes, and a decreased number of goblet cells were found by impression cytology in different areas of the KCS conjunctiva. The presence of snake-like chromatin was significantly correlated with the severity of the disease. No nuclear changes were found in the control group. Conclusions We assume these findings can be attributed to a natural regeneration of conjunctival cells and to resistance to a pathological reaction to KCS.
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Pflugfelder, Stephen, Fang Bian, Koray Gumus, William Farley, Michael Stern et Cintia De Paiva. « Severity of Sjögren’s Syndrome Keratoconjunctivitis Sicca Increases with Increased Percentage of Conjunctival Antigen-Presenting Cells ». International Journal of Molecular Sciences 19, no 9 (14 septembre 2018) : 2760. http://dx.doi.org/10.3390/ijms19092760.

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This study investigated the relationship between clinical severity and percentage of conjunctival antigen-presenting cells (APCs) in Sjögren’s syndrome (SS)-associated keratoconjunctivitis sicca (KCS). KCS clinical severity was based on symptom severity, tear volume, tear break-up time, and ocular surface dye staining. Conjunctival goblet cell density (GCD) was measured in periodic acid Schiff (PAS)-stained membranes. Conjunctival cells obtained by impression cytology were used for flow cytometry to measure percentages of CD45+HLA-DR+ APCs and mature CD11c+CD86+ dendritic cells (DCs). Compared to normal conjunctiva, the percentages of HLA-DR+ and CD11c+CD86+ cells were higher in the conjunctiva of the KCS group (p < 0.05). The percentage of CD45+HLA-DR+ cells positively correlated with clinical severity (r = 0.71, p < 0.05) and negatively correlated with GCD (r = −0.61, p < 0.05). Clinical severity also negatively correlated with GCD (r = −0.54, p < 0.05). These findings indicate that a higher percentage of APCs and mature DCs in the conjunctiva is associated with more severe KCS in SS. These APCs may contribute to the generation of the pathogenic Th1 cells that cause goblet cell loss in KCS.
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ATHANASIOU, L. V., D. Ε. PSEMMAS et N. PAPAIOANNOU. « Conjunctival cytology assessment in dogs and cats. Sampling, diagnostic techniques and findings ». Journal of the Hellenic Veterinary Medical Society 69, no 1 (2 mai 2018) : 701. http://dx.doi.org/10.12681/jhvms.16382.

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The conjunctiva provides a physical and physiological barrier against microorganisms and foreign bodies and also contributes to the ocular immunological defense. It constitutes a straightforward and accessible tissue for sampling and examination. Sampling indications include: changes in color, surface irregularities, thickening, or masses, ocular discharge and the identification of infectious organisms. Samples for conjunctival evaluation may be collected with exfoliative or abrasive techniques, aspiration, impression and conjunctival biopsy. The most commonly used and clinically useful laboratory methods for the assessment of conjunctival specimens are: microscopic examination of cytological preparations, culture and susceptibility testing, live virus isolation, polymerase chain reaction, direct immunofluorescent antigen test and histopathological examination for snip biopsies. Findings like inflammatory or neoplastic cells, cellular alterations, inclusion bodies and microorganisms, offer valuable information not only for localized ocular disorders, but for systemic diseases as well.
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Kim, J. W. « Conjunctival impression cytology of the filtering bleb ». Korean Journal of Ophthalmology 11, no 1 (1997) : 25. http://dx.doi.org/10.3341/kjo.1997.11.1.25.

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P, Muralidharan, et Amudha Vadivu Subramaniyan. « CONJUNCTIVAL IMPRESSION CYTOLOGY (CIC)- TECHNIQUE AND INTERPRETATION ». Journal of Evidence Based Medicine and Healthcare 4, no 28 (5 avril 2017) : 1652–54. http://dx.doi.org/10.18410/jebmh/2017/322.

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Pilson, Qistina, Caroline A. Jefferies, Joan Ní Gabhann et Conor C. Murphy. « Isolation of microRNA from conjunctival impression cytology ». Experimental Eye Research 132 (mars 2015) : 109–14. http://dx.doi.org/10.1016/j.exer.2015.01.009.

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Garcher, C., I. Bara, A. Bron et G. Guyonnet. « Immunocharacterization of conjunctival mucins with impression cytology ». Experimental Eye Research 55 (septembre 1992) : 104. http://dx.doi.org/10.1016/0014-4835(92)90568-d.

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Paridaens, A. D., A. C. McCartney, O. M. Curling, C. J. Lyons et J. L. Hungerford. « Impression cytology of conjunctival melanosis and melanoma. » British Journal of Ophthalmology 76, no 4 (1 avril 1992) : 198–201. http://dx.doi.org/10.1136/bjo.76.4.198.

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Anshu, M. M. Munshi, V. Sathe et A. Ganar. « Conjunctival impression cytology in contact lens wearers ». Cytopathology 12, no 5 (23 octobre 2001) : 314–20. http://dx.doi.org/10.1046/j.1365-2303.2001.00349.x.

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Kushwah, Swati, Sangeetha Thamodharan et Kalyani Raju. « Evaluation of tear function and ocular surface changes in patients with pseudoexfoliation ». Indian Journal of Clinical and Experimental Ophthalmology 9, no 3 (15 septembre 2023) : 354–58. http://dx.doi.org/10.18231/j.ijceo.2023.067.

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This study intends to evaluate the Tear function and ocular surface changes in patients with pseudoexfoliation.This cross-sectional study will be conducted on a minimum of 45 patients fulfilling the inclusion criteria in the department of Ophthalmology, at tertiary care institute. Tear meniscus height (TMH), Schirmer’s test, tear breakup time (TBUT), fluorescein staining, conjunctival impression cytology were used to assess dry eye disease in pseudoexfoliation (PEX) patients. In our study the majority of patients with PEX were &#62;70 years and females (23) are more than males (22). According to Grading of dry eye, 41(45.5%) were moderate grade, 24(26.7%) were mild grade, 13(14.5%) were severe grade and 12 (13.3%) were normal grade. Conjunctival impression cytology, fluorescein staining, TBUT, Schirmer's tests, and TMH, all showed a statistically significant results with dry eye in the current study. The patients with pseudoexfoliation syndrome are more prone to develop dry eye, as it causes tear film irregularities and a reduction in the number of goblet cells which is evident with conjunctival impression cytology and Tear film tests.
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Elwan, Asmaa, Mona Aly, Hanan Hegazy et Amany Abosaif. « Conjunctival Impression Cytology in Patients with Thyroid Disorders ». International Journal of Medical Arts 4, no 2 (1 février 2022) : 2188–94. http://dx.doi.org/10.21608/ijma.2022.106467.1394.

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Adar, Serap, Ayfer Kanpolat, Selcuk S??r??c? ? et ? ? ??m??r Ucakhan. « Conjunctival Impression Cytology in Patients Wearing Contact Lenses ». Cornea 16, no 3 (mai 1997) : 289???294. http://dx.doi.org/10.1097/00003226-199705000-00006.

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Chaparala, Padmini, Aruna Kumari Prayaga et Raghunadha Rao Digumarti. « Significance of Acellular Smears in Conjunctival Impression Cytology ». Acta Cytologica 56, no 5 (2012) : 539–42. http://dx.doi.org/10.1159/000342495.

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de Queiroga, Isabella Bezerra Wanderley, Luiz Antônio Vieira, Jeison de Nadai Barros, Margareth de Fátima Formiga Melo Diniz et Liana Clébia Soares Lima de Morais. « Conjunctival Impression Cytology Changes Induced by Oral Isotretinoin ». Cornea 28, no 9 (octobre 2009) : 1009–13. http://dx.doi.org/10.1097/ico.0b013e3181a16858.

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Tseng, Scheffer C. G. « Staging of Conjunctival Squamous Metaplasia by Impression Cytology ». Ophthalmology 92, no 6 (juin 1985) : 728–33. http://dx.doi.org/10.1016/s0161-6420(85)33967-2.

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Maskin, Steven L., et Donald D. Bode. « Electron Microscopy of Impression-acquired Conjunctival Epithelial Cells ». Ophthalmology 93, no 12 (décembre 1986) : 1518–23. http://dx.doi.org/10.1016/s0161-6420(86)33538-3.

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Amrayni, Maretha, Elsa Gustianty, Susi Heryati, Andika Prahasta, Maula Rifada et Hasrayati Agustina. « Comparison of Ocular Surface Cytological Appearance in Glaucoma Patient Treated with Timolol Maleat 0,5% Latanoprost 0,005% and Timolol-Latanoprost Fixed Combination Preservative Free Eye Drop ». Ophthalmologica Indonesiana 44, no 2 (1 avril 2019) : 82. http://dx.doi.org/10.35749/journal.v44i2.167.

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Introduction : The longterm use of topical antiglaucoma might cause ocular surface instability due to active substance or preservative used. Impression cytology examination may reveal superficial epithelial cells on conjunctiva and cornea, including goblet cells. Goblet cell density decrease is the most important parameter on evaluation of ocular surface disorder. Objective : This study was to understand ocular surface remodeling due to active substance of topical antiglaucoma with impression cytology examination among the patient prior and 3 months after therapy. Methods : This was a randomized controlled trial study with single blind masking. A total of 45 eyes from 31 patients were used as subject and distributed onto three groups treatment, which were timolol maleat 0.5%, latanoprost 0.005%, and latanoprost-timolol maleat fixed combination. All topical antiglaucoma in this study were preservative free. Result : There were differences between 3 groups in goblet cells density after 3 months therapy (p=0,030). Goblet cell density in timolol group was lower than latanoprost (p=0,041) and fixed combination (p=0,045). There was no significantly difference between 3 groups in conjunctival epithelial metaplasia degree (p=0,706) and cell to cell contact degree in corneal epithelial cells (p=0.66) after 3 months therapy. Conjunctival epithelial metaplasia degree were increased among group of timolol (p=0,008) and fixed combination (p=0,046). Conclusion : Timolol maleat 0,5% caused lower goblet cell density after 3 months therapy compare with latanoprost and fixed combination. There was no significantly difference in conjunctival epithelial metaplasia and cell to cell contact degree in corneal epithelial cells among these glaucoma treatment groups.
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Joseph, Serah, C. M. Kiran, Bhagwati Wadwekar et Surendra Nirmale. « Conjunctival Impression Cytology in Evaluating Tear Film Status in Small Incision Cataract Surgery ». Indian Journal of Pathology : Research and Practice 7, no 4 (2018) : 483–87. http://dx.doi.org/10.21088/ijprp.2278.148x.7418.13.

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H. V, Pooja, et H. T. Venkate Gowda. « Cytopathological changes on conjunctival impression cytology in computer users ». IP International Journal of Ocular Oncology and Oculoplasty 4, no 4 (15 janvier 2019) : 163–65. http://dx.doi.org/10.18231/2581-5016.2018.0042.

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Erdogan, Haydar, D. Sema Arici, M. Ilker Toker, M. Kemal Arici, Gonul Fariz et Aysen Topalkara. « Conjunctival impression cytology in pseudoexfoliative glaucoma and pseudoexfoliation syndrome ». Clinical and Experimental Ophthalmology 34, no 2 (mars 2006) : 108–13. http://dx.doi.org/10.1111/j.1442-9071.2006.01168.x.

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Reddy, V., V. Rao, Arunjyothi et M. Reddy. « Conjunctival impression cytology for assessment of vitamin A status ». American Journal of Clinical Nutrition 50, no 4 (1 octobre 1989) : 814–17. http://dx.doi.org/10.1093/ajcn/50.4.814.

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Pasolini, Maria Pia, Davide De Biase, Michele Greco, Giusy Napoleone, Veronica Palumbo, Pierpaolo Coluccia, Orlando Paciello et Barbara Lamagna. « Impression Technique for Conjunctival Exfoliative Cytology in Healthy Horses ». Journal of Equine Veterinary Science 67 (août 2018) : 75–80. http://dx.doi.org/10.1016/j.jevs.2018.03.011.

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Resnikoff, Serge, R�gine Luzeau, Gilles Filliard et Olivier Amedee-Manesme. « Impression cytology with transfer in xerophtalmia and conjunctival diseases ». International Ophthalmology 16, no 6 (novembre 1992) : 445–51. http://dx.doi.org/10.1007/bf00918435.

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Chowdhury, Swapan, N. K. Ganguly, Minni Verma, Rajesh Kumar, Lata Kumar et B. N. S. Walia. « Dynamics of conjunctival impression cytologic changes after vitamin A supplementation ». British Journal of Nutrition 77, no 6 (juin 1997) : 863–69. http://dx.doi.org/10.1079/bjn19970085.

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AbstractTo investigate the chronological changes in conjunctival epithelium after supplementation with a massive oral dose of vitamin A, conjunctival impression cytology (CIC) with transfer was carried out repeatedly among 200 children aged 6–120 months in a randomized, double-blind, placebo-controlled study in Chandigarh (India). Significant conversion to normal CIC started 71–80 d after vitamin A supplementation and by 101–110d conversion had taken place in all children. Compared with the placebo group, plasma retinol concentration at 100d post-supplement was found to be significantly higher in the vitamin A-supplemented group P = 0·04. This study demonstrates that CIC responds to a massive oral dose of vitamin A 3–4 months after supplementation. These findings should guide future studies and evaluations in which CIC is used to assess response to vitamin A interventions.
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Radziejewski, Krzysztof, Ireneusz Balicki et Mateusz Szadkowski. « Assessment of corneal and conjunctival metaplasia by impression cytology during the treatment of canine keratoconjunctivitis sicca ». Acta Veterinaria Hungarica 66, no 2 (juin 2018) : 189–203. http://dx.doi.org/10.1556/004.2018.018.

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The purpose of this study was to assess the condition of cells in the conjunctiva and corneal epithelium prior to and during cyclosporine- or tacrolimusbased treatment of keratoconjunctivitis sicca (KCS). The study was performed on 40 dogs with KCS. The dogs were divided into two groups of 20 animals each. In Group I, 0.75% cyclosporine eye drops were administered three times a day, while in Group II 0.02% tacrolimus eye drops were administered twice daily. Additionally, each group was subdivided into three subgroups based on the results of the Schirmer I tear test (STT I). Evaluation of cellular metaplasia in the cornea and the palpebral and bulbar conjunctiva based on the Nelson–Adams scale was performed by impression cytology using Millipore round filters (Millipore VSWP 01300 DA) of 25 μm pore diameter applied to the studied area. Ophthalmological and cytological examinations were performed prior to the treatment as well as after one and two months of therapy. In both groups, a decrease in Nelson–Adams values was observed, corresponding to the increasing STT values [Rxy Spearman statistically significant correlation coefficient values between –0.75 (P < 0.001) and –0.45 (P < 0.01)]. The absence of goblet cells was observed in all dogs, regardless of the KCS stage. Goblet cells reappeared following both tacrolimus- and cyclosporine-based treatment in impression cytology specimens classified as 0 in the Nelson–Adams scale. The extent of corneal and conjunctival metaplasia in the course of tacrolimus- and cyclosporine-based treatment of KCS decreases with increasing STT values.
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Bandyopadhyay, Ranjana, Dipanwita Nag, SantoshK Mondal, Susmita Gangopadhyay, Ketaki Bagchi et Gautam Bhaduri. « Ocular surface disorder in pterygium : Role of conjunctival impression cytology ». Indian Journal of Pathology and Microbiology 53, no 4 (2010) : 692. http://dx.doi.org/10.4103/0377-4929.72036.

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Shen, Joanne F., Timothy T. McMahon, E. Lillian Cheng, Joel Sugar, Beatrice Y. J. T. Yue, Robert J. Anderson, Carolyn Begley et Jie Zhou. « Lysosomal Hydrolase Staining of Conjunctival Impression Cytology Specimens in Keratoconus ». Cornea 21, no 5 (juillet 2002) : 447–52. http://dx.doi.org/10.1097/00003226-200207000-00003.

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Corrales, Rosa M., Margarita Calonge, Jose M. Herreras, Victoria Saez et Felipe J. Chaves. « Human Epithelium from Conjunctival Impression Cytology Expresses MUC7 Mucin Gene ». Cornea 22, no 7 (octobre 2003) : 665–71. http://dx.doi.org/10.1097/00003226-200310000-00010.

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Barros, Jeison de Nadai, Márcia Serva Lowen, Vera Lucia Degaspare Monte Mascaro, Thais Piedade de Andrade et Maria Cristina Martins. « Impression cytology features of conjunctival nevi reported as more noticeable ». Arquivos Brasileiros de Oftalmologia 72, no 2 (avril 2009) : 205–10. http://dx.doi.org/10.1590/s0004-27492009000200014.

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Fuchs, G. J., S. Ausayakhun, S. Ruckphaopunt, A. Tansuhaj et R. M. Suskind. « Relationship between vitamin A deficiency, malnutrition, and conjunctival impression cytology ». American Journal of Clinical Nutrition 60, no 2 (1 août 1994) : 293–98. http://dx.doi.org/10.1093/ajcn/60.2.293.

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Muniesa, M. J., S. González, P. Buetas, S. López, C. Sánchez et X. Matias-Guiu. « Evaluation of conjunctival epithelium of filtering blebs by impression cytology ». Archivos de la Sociedad Española de Oftalmología (English Edition) 89, no 6 (juin 2014) : 216–21. http://dx.doi.org/10.1016/j.oftale.2013.07.002.

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Hong, Samin, Christopher Seungkyu Lee, Kyoung Yul Seo, Gong Je Seong et Young Jae Hong. « Effects of Topical Antiglaucoma Application on Conjunctival Impression Cytology Specimens ». American Journal of Ophthalmology 142, no 1 (juillet 2006) : 185–86. http://dx.doi.org/10.1016/j.ajo.2006.02.056.

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Bhatia, R. P., Roy Lipika, R. S. Garbyal et Kumar Mohan. « Corneal and Conjunctival Impression Cytology in Soft Contact Lens Wearers ». Annals of Ophthalmology 38, no 2 (2006) : 117–20. http://dx.doi.org/10.1385/ao:38:2:117.

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Nolan, Glenda R., Lawrence W. Hirst, R. Gordon Wright et B. Josephine Bancroft. « Application of impression cytology to the diagnosis of conjunctival neoplasms ». Diagnostic Cytopathology 11, no 3 (octobre 1994) : 246–49. http://dx.doi.org/10.1002/dc.2840110310.

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Gathinavar, SalmanS, JayashreeP Menashinkai, Shilpa Umarani et ShruthiMrityunjaya Agadi. « Conjunctival impression cytology in chronic cement exposure : A comparative study ». TNOA Journal of Ophthalmic Science and Research 61, no 1 (2023) : 67. http://dx.doi.org/10.4103/tjosr.tjosr_108_22.

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Randon, Matthieu, et Rachid Abbas. « The In Vivo Effect of a Prostaglandin on the Conjunctival Goblet Cells ». Ophthalmology – Open Journal 5, no 1 (30 décembre 2022) : 4–9. http://dx.doi.org/10.17140/ooj-5-123.

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Introduction To evaluate the density of conjunctival goblet cells (GCs) from in vivo confocal microscopy (IVCM) and impression cytology (IC) and mucin expression in ten glaucomatous patients treated with preservative-free latanoprost (Monoprost®) Methods Ten glaucomatous patients (10 eyes) were enrolled. Conjunctiva was examined clinically and morphologically by IVCM and IC. Both IVCM and IC were performed at baseline, and after the 1st and 4th month of Monoprost® therapy. GC density (GCD) in cells⁄mm2 was the main outcome measurement. Results At baseline, mean GCD was 147+/-78 cells/mm2 for IVCM and 114+/-62 cells/mm2 for IC GCD. At month one, mean GCD was 149+/-69 and 120+/-56 measured with IVCM and IC, respectively (p=0.31 for IVCM and p=0.40 for IC). At month four, GCD increased to 162+/-81 and 134+/-61 measured with IVCM and IC, respectively (p=0.02 for IVCM and p=0.02 for IC). Conclusion Treatment with preservative-free (PF) latanoprost was associated with an increase in conjunctival GCD in glaucomatous eyes. Further studies are mandatory to verify this finding because its validation may have important consequences in the medical management of glaucoma.
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Kulkarni, C. V. « Cytopathological changes on CIC (Conjunctival Impression Cytology) among computer users : A study of 150 cases ». Journal of Medical Science And clinical Research 05, no 05 (12 mai 2017) : 21693–97. http://dx.doi.org/10.18535/jmscr/v5i5.74.

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Iqbal, Jawed, et Arjun Chaudhary. « Therapeutic Assessment of Conjunctival Impression Cytology in Vitamin A Deficient Children ». IOSR Journal of Dental and Medical Sciences 16, no 05 (juin 2017) : 50–53. http://dx.doi.org/10.9790/0853-1605125053.

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