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1
Gasparini, Evel. Il matriarcato slavo. Sous la direction de Marcello Garzaniti et Donatella Possamai. Florence : Firenze University Press, 2010. http://dx.doi.org/10.36253/978-88-8453-999-1.
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This book on Slavic matriarchy is the result of the studies and researches that Evel Gasparini carried out over the span of his lifetime. Intrigued by the possibility of a close link between the collective ownership of the land and the ancient agricultural-matriarchal substrate of Slav culture, Gasparini launched on the titanic enterprise of analysing the archaeological and historical sources of early Slavic civilisation. Basing himself on a concept of culture elaborated in the ethnological field, he brought to light certain contradictions in the application of the Indo-European paradigm to Slavic culture and identified a series of elements illustrating the matriarchal substrate. Exploiting an uncommon knowledge of cultural anthropology and profound linguistic competencies, in this book Gasparini maps out a complex panorama ranging from the economy to the social structure and from the religious traditions to music and dance. Out of print for some time, the book is now proposed in a new, more convenient form, complete with an appendix on Finns and Slavs – which was originally intended as another chapter in the book but was then left out – a detailed preface by Gasparini's disciple Remo Faccani, and a bibliography of the scholar's oeuvre edited by Donatella Possamai.
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Goldstein, Alan S. Catalytic oxidations of organic substrates by transition metal salts. 1991.
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Estimation of complex permittivity of composite multilayer material at microwave frequency using waveguide measurements. Hampton, VA : National Aeronautics and Space Administration, Langley Research Center, 2003.
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Ang, Xiaolu Lulu Lim. Substrates of the SCF-beta-TRCP E3 ubiquitin ligase complex : Mechanisms of recognition and delivery to the proteasome. 2009.
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Garvey, Marjorie A. TMS : neurodevelopment and perinatal insults. Sous la direction de Charles M. Epstein, Eric M. Wassermann et Ulf Ziemann. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780198568926.013.0022.
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Neural substrate for changes in neuromotor skills of typically developing children involves the complex and organized maturation of underlying brain structures. This article gives an overview of the changes that occur in motor function, as children get older and those aspects of central nervous development which may form the neural substrates of motor function development. It describes those TMS evoked parameters, related to the motor system, that have been studied in both typically developing children and in those who have suffered perinatal insults to the central nervous system. TMS has its limitations and is especially useful when used in combination with other neurophysiological modalities. The focus for future studies should be on correlating TMS evoked parameters with behavioural measures in typically developing children and explanation of the neural substrates of the motor abnormalities in children with perinatal insults and developmental disabilities.
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Amzica, Florin, et Fernando H. Lopes da Silva. Cellular Substrates of Brain Rhythms. Sous la direction de Donald L. Schomer et Fernando H. Lopes da Silva. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228484.003.0002.
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The purpose of this chapter is to familiarize the reader with the basic electrical patterns of the electroencephalogram (EEG). Brain cells (mainly neurons and glia) are organized in multiple levels of intricate networks. The cellular membranes are semipermeable media between extracellular and intracellular solutions, populated by ions and other electrically charged molecules. This represents the basis of electrical currents flowing across cellular membranes, further generating electromagnetic fields that radiate to the scalp electrodes, which record changes in the activity of brain cells. This chapter presents these concepts together with the mechanisms of building up the EEG signal. The chapter discusses the various behavioral conditions and neurophysiological mechanisms that modulate the activity of cells leading to the most common EEG patterns, such as the cellular interactions for alpha, beta, gamma, slow, delta, and theta oscillations, DC shifts, and some particular waveforms such as sleep spindles and K-complexes and nu-complexes.
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Guo, Yong, et Claudia F. Lucchinetti. Taking a Microscopic Look at Multiple Sclerosis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199341016.003.0005.
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The pathology of multiple sclerosis is complex, extends beyond the white matter plaque, and is influenced by stage of demyelinating activity, clinical course, disease duration, and treatment. Technological advances in immunology, molecular biology, and “omic” biology have provided novel insights into the mechanisms for development of white matter plaques, axonal damage, cortical demyelination, and disease progression. Detailed, systematic, and statistically rigorous pathological studies on clinically well-characterized MS cohorts have helped define the heterogeneous pathological substrates of MS and unravel the complex molecular pathogenic mechanisms, with the ultimate goal of identifying targets for therapeutic interventions. It is increasingly clear that the use of human tissues is imperative to improve current diagnostic, prognostic, and therapeutic modalities. Preclinical animal models have been invaluable for discovery of key immune processes, basic disease mechanisms, and candidate immune targeting strategies, but the conclusions have yet be reconciled with the essential features of the human disease.
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Guo, Lucie Y. Aph-1 is a substrate-binding site within the γ-secretase complex. 2010.
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Liaw, Ean-Tun. Characterization of substrate-velocity relationships for the cellulase enzyme complex from Trichoderma viride. 1989.
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Vaghi, M. M., et T. W. Robbins. Task-Based Functional Neuroimaging Studies of Obsessive-Compulsive Disorder : A Hypothesis-Driven Review. Sous la direction de Christopher Pittenger. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228163.003.0022.
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The neurobiological basis of Obsessive Compulsive Disorder (OCD) has been probed using functional magnetic resonance in hundreds of studies over three decades. This complex literature can be syntheized using a theory-informed approach. At a theoretical level, separable, independent, constructs of relevance to OCD have been identified. At the experimental level, extensive translational evidence has provided an account that relates specific brain systems to these neuropsychological constructs. Parallels between neural substrates implicated in OCD and functional specialization of different brain regions suggest that abnormalities within fronto-striatal circuitry impinge on executive functions, and their subcomponents, and on goal-directed learning and habit formation. In OCD, this is reflected at a functional level in patterns of abnormal activations in particular brain regions during specific cognitive tasks. However, many issues still need to be addressed. The authors suggest that the experimental context might represent a pivotal variable that should be taken into account.
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Trimmer, Barry. Soft-bodied terrestrial invertebrates and robots. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0041.
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Studies of animal locomotion and its control have generally focused on species with articulated, stiff skeletons, largely ignoring the contributions of soft tissues. Attempts to create animal-like performance in robots illustrate the limitations of using rigid-body mechanics alone. There is a growing appreciation that soft structures are critical for producing robust and adaptable behaviors in complex environments. Studies of predominantly soft animals could help to accelerate our understanding of the biomechanical role of deformable materials and their control. This chapter focuses on our current understanding of locomotion in terrestrial soft animals. It highlights the critical distinction between purely hydrostatic systems that control movements by pressurization and those that can remain relatively soft and exploit stiff substrates (the environmental skeleton strategy). The final section describes biomimetic devices that have been inspired by both animal strategies to show how such biological solutions might be employed to build controllable, highly deformable mobile machines.
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Mottram, Linda-Jayne, et Gavin G. Lavery. The metabolic and nutritional response to critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0202.
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The metabolic response to critical illness is complex and affects every body system. The first phase of this response is characterized by increased hypothalamic pituitary activity and resistance (decreased response) to effector hormones in many target tissues. Cytokines released in the early stages of such illness may be important as they appear to stimulate the hypothalamic pituitary axis directly as part of this ‘stress response’. This phase is considered ‘adaptive’ (helpful), increasing the availability of glucose, free fatty acids, and amino acids as substrates for vital organs. However, in prolonged illness, the neuroendocrine response is very different with damped hypothalamic responses, leading to a state in which catabolism predominates, leading to what might be termed the critical illness wasting syndrome. The gastrointestinal (GI) failure often associated with prolonged critical illness appears to be due, at least in part, to an altered neuroendocrine environment. The poor nutritional state associated with GI failure exacerbates the catabolic response, prolonging illness and the period of intensive care management required by the patient. The result is increased mortality and, in survivors, a more prolonged recovery/rehabilitation process.
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Chen, Allen Ching-Way. Aph-1 functions as a substrate docking site within the Alzheimer's disease relevant gamma-secretase complex. 2009.
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Arbib, Michael A. When Brains Meet Buildings. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190060954.001.0001.
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Understanding our brains can enrich our understanding of the ways we act and interact in a complex world, and how our experience of the built environment helps shape who we are and yet can be shaped by us in turn. This book presents action-oriented perception, memory, and imagination as keys to unlocking the neuroscience of the experience and design of architecture, and explores what it might mean for buildings to have “brains.” It offers a conversation addressed not only to architects and scientists but also to all who share a fascination with the brains within them and the buildings around them. Analysis of famous buildings and of homely examples introduces concepts like aesthetics, affordances, atmosphere, construction, manual action, scripts, and wayfinding, and the search for their neural substrates. It explores how evolution shaped a language-ready brain that is also architecture-ready. Case studies of the Guggenheim Museum Bilbao and the Sydney Opera House introduce an account of how the brains and minds of architects operate, pursuing the idea that memory and imagination are interacting forms of mental construction, but that architectural design must eventually reach a form that can guide the physical construction of buildings. All these concerns set new challenges for collaboration between architects and neuroscientists, and for further research on the brains of humans and animals.
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Erdem, Uğur Murat, Nicholas Roy, John J. Leonard et Michael E. Hasselmo. Spatial and episodic memory. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0029.
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The neuroscience of spatial memory is one of the most promising areas for developing biomimetic solutions to complex engineering challenges. Grid cells are neurons recorded in the medial entorhinal cortex that fire when rats are in an array of locations in the environment falling on the vertices of tightly packed equilateral triangles. Grid cells suggest an exciting new approach for enhancing robot simultaneous localization and mapping (SLAM) in changing environments and could provide a common map for situational awareness between human and robotic teammates. Current models of grid cells are well suited to robotics, as they utilize input from self-motion and sensory flow similar to inertial sensors and visual odometry in robots. Computational models, supported by in vivo neural activity data, demonstrate how grid cell representations could provide a substrate for goal-directed behavior using hierarchical forward planning that finds novel shortcut trajectories in changing environments.
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Domhoff, G. William. Dreaming Is an Intensified Form of Mind-Wandering, Based in an Augmented Portion of the Default Network. Sous la direction de Kalina Christoff et Kieran C. R. Fox. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780190464745.013.7.
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This chapter argues that dreaming is an intensified form of mind-wandering that makes use of embodied simulation. It further hypothesizes that the neural network that enables dreaming is very likely an augmented portion of the default network. This network is activated whenever there is (1) a mature and intact neural substrate that can support the cognitive process of dreaming; (2) an adequate level of cortical activation; (3) an occlusion of external stimuli; (4) a cognitively mature imagination system (a necessity indicated by the virtual lack of dreaming in preschoolers and its relative paucity until ages 8–9); and (5) the loss of conscious self-control, which may be neurologically mediated in the final step in a complex process by the decoupling of the dorsal attentional network from the anterior portions of the default network. If this testable theory proves to be correct, then dreaming may be the quintessential cognitive simulation.
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Oliveira, Warlley Fernandes, Nívea Taís Vila, Alexandre José Sousa Ferreira, Simone Fiori et Márcia Gomes da Silva. Tingimento natural de algodão cationizado com extrato dos frutos de jenipapo (Genipa americana L.). Seven Editora, 2022. http://dx.doi.org/10.56238/sevedi40374-010.
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A maioria dos corantes naturais é extraída de fontes vegetais que podem fornecer uma variedade de cores e tonalidades diferentes. Apesar disso, as fontes naturais de tons de azul são muito raras e de complexa estabilização, dificultando a aplicação desses corantes em substratos têxteis. Nesse contexto, os frutos do jenipapo (Genipa americana L.) encontrados no Brasil são uma fonte de coloração azul natural com grande potencial para a indústria têxtil. O objetivo deste estudo inicial foi investigar o tingimento do algodão com o extrato obtido a partir dos frutos verdes de jenipapo, onde foi avaliada a estabilização da cor azul do extrato. O tingimento foi otimizado considerando a influência das variáveis temperatura e pH do banho de tingimento na intensidade de cor dos tecidos tingidos. Também foi avaliado o fator de proteção UV (UPF) das amostras tingidas nas condições otimizadas. O extrato dos frutos verdes de jenipapo se mostrou estável no intervalo de tempo estudado. O melhor resultado de intensidade de cor foi obtido na temperatura de 80 °C e pH 4,0. O fator de proteção UV (UPF) dos tecidos tingidos apresentou um aumento significativo após o processo de tingimento. As propriedades de solidez à lavagem e à fricção também foram avaliadas.
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See, Sam. Queer Natures, Queer Mythologies. Sous la direction de Christopher Looby et Michael North. Fordham University Press, 2020. http://dx.doi.org/10.5422/fordham/9780823286980.001.0001.
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This book collects the scholarly work that Sam See had completed as of his death in 2013. It includes essays that have been previously published in leading journals as well as materials that remained unpublished. Its parts represent the two book projects that See hoped to complete: Queer Natures: Feeling Degenerate in Literary Modernism and Queer Mythologies: Community and Memory in Modern Literature. The first reinterprets the key term nature, central to so many discussions of literature and sexuality. For See, nature is no longer an unchanging substrate or a philosophical given. Relying on a thorough reading of Darwin, See argues instead that nature is constantly and aimlessly variable. Since it makes room for the aesthetic, by way of what Darwin called sexual selection, nature is also affected by feeling. On these grounds, See argues that nature itself might be considered queer. The second project proposes that, understood as queer in this way, nature might be made the foundational myth for the building of queer communities. See looks at the ways in which queer community has been imagined in literary works from a wide range of authors, and he analyzes the role that literature has played in providing significant aesthetic versions of that community. Locating the various failures of these myths is a way, he hopes, of approaching another, more successful communal story. In addition to his reading of Darwin, See provides new interpretations of modern writers including Langston Hughes, Virginia Woolf, Oscar Wilde, Hart Crane, and T. S. Eliot.
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Daguerre, Blandine. Passage et écriture de l’entre-deux dans El Pasajero de Cristóbal Suárez de Figueroa. Presses Universitaires de Pau et des Pays de l'Adour, 2020. http://dx.doi.org/10.46608/primaluna3.9782353111220.
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Espagne, premier quart du XVIIe siècle : quatre hommes se rencontrent au cours d’un voyage entre Madrid et Barcelone où ils doivent partir pour l’Italie pour y tenter leur chance. Pour lutter contre la pénibilité de leur périple et éviter l’ennui, ils décident de converser. S’ensuit un échange de plus de 200 pages autour de leur destination, de leur parcours personnel respectif, de la société de l’époque au sein duquel viennent s’intercaler des récits à vocation plus ludique. Telle est l’intrigue de El Pasajero, advertencias utilísimas a la vida humana, œuvre citée par bon nombre de spécialistes du Siècle d’Or qui s’attachent tous à saluer ses qualités littéraires et à laquelle aucune étude littéraire de fond n’a été consacrée. Comment expliquer un tel paradoxe? El Pasajero propose un caléidoscope de la société de l’époque, d’où l’orientation sociologique de la plupart des études réalisées sur ce texte. La mauvaise presse de son auteur connu pour son tempérament peu amène et pour son opposition à Cervantès, a pu y contribuer également de manière plus tangentielle. Enfin et surtout, la richesse textuelle, littéraire et idéologique de El Pasajero peut avoir freiné certaines ambitions analytiques. Le texte de Figueroa est d’une nature profondément hybride, il se caractérise par un oscillement perpétuel entre inspiration italienne, accents décaméroniens, emprunts transtextuels et substrat folklorique hispanique. Il joue sur la porosité des frontières entre réalité et fiction pour élaborer un texte dont tous les éléments semblent dialoguer et entre lesquels le lecteur passe comme sur les pierres d’un gué. En fin de compte, El Pasajero est un véritable laboratoire d’expérimentation littéraire où affleurent traditions littéraires ancrées et propositions d’écriture plus innovantes. Ce dialogue perpétuel est décisif dans l’œuvre : au-delà d’un premier dialogue évident entre les personnages, le texte en propose d’autres en filigrane, entre les formes et les genres littéraires. Ils fonctionnent comme autant d’éléments structurants au sein de cette œuvre pensée comme un lieu de passage où se mêlent expérimentations littéraires et réflexions sociétales. El Pasajero peut parfois laisser le lecteur perplexe, c’est un fait. Il fait, néanmoins, partie de ces textes qui fascinent et qui n’ont pas encore révélé tous leurs secrets. Une chose est certaine : El Pasajero ne laisse pas indifférent et mérite qu’on lui consacre une étude de fond. C’est ce que se propose de faire cet ouvrage…