Bibliographies thématiques / Chromate resistance

Littérature scientifique sur le sujet « Chromate resistance »

Auteur : Grafiati
Publié le 10 mars 2023

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Articles de revues sur le sujet "Chromate resistance"

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Cervantes, Carlos, et Simon Silver. « Plasmid chromate resistance and chromate reduction ». Plasmid 27, no 1 (janvier 1992) : 65–71. http://dx.doi.org/10.1016/0147-619x(92)90007-w.

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Ohtake, Hisao, Kohya Komori, Carlos Cervantes et Kiyoshi Toda. « Chromate-resistance in a chromate-reducing strain of Enterobacter cloacae ». FEMS Microbiology Letters 67, no 1-2 (janvier 1990) : 85–88. http://dx.doi.org/10.1111/j.1574-6968.1990.tb13841.x.

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Ohtake, H., C. Cervantes et S. Silver. « Decreased chromate uptake in Pseudomonas fluorescens carrying a chromate resistance plasmid. » Journal of Bacteriology 169, no 8 (1987) : 3853–56. http://dx.doi.org/10.1128/jb.169.8.3853-3856.1987.

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Alvarez, Angel H., Rafael Moreno-Sánchez et Carlos Cervantes. « Chromate Efflux by Means of the ChrA Chromate Resistance Protein from Pseudomonas aeruginosa ». Journal of Bacteriology 181, no 23 (1 décembre 1999) : 7398–400. http://dx.doi.org/10.1128/jb.181.23.7398-7400.1999.

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ABSTRACT Everted membrane vesicles of Pseudomonas aeruginosaPAO1 harboring plasmid pCRO616, expressing the ChrA chromate resistance protein, accumulated four times more51CrO4 2− than vesicles from plasmidless cells, indicating that a chromate efflux system functions in the resistant strain. Chromate uptake showed saturation kinetics with an apparent Km of 0.12 mM chromate and aV max of 0.5 nmol of chromate/min per mg of protein. Uptake of chromate by vesicles was dependent on NADH oxidation and was abolished by energy inhibitors and by the chromate analog sulfate. The mechanism of resistance to chromate determined by ChrA appears to be based on the active efflux of chromate driven by the membrane potential.
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Julián‐Sánchez, Adriana, César Díaz‐Pérez, Carlos Cervantes et Héctor Riveros‐Rosas. « Phylogenetic Analysis of Chromate Resistance Determinants ». FASEB Journal 22, S2 (avril 2008) : 246. http://dx.doi.org/10.1096/fasebj.22.2_supplement.246.

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Acosta-Navarrete, Yaned M., Yhoana L. León-Márquez, Karina Salinas-Herrera, Irvin E. Jácome-Galarza, Víctor Meza-Carmen, Martha I. Ramírez-Díaz et Carlos Cervantes. « Expression of the six chromate ion transporter homologues of Burkholderia xenovorans LB400 ». Microbiology 160, no 2 (1 février 2014) : 287–95. http://dx.doi.org/10.1099/mic.0.073783-0.

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The chromate ion transporter (CHR) superfamily comprises transporters that confer chromate resistance by extruding toxic chromate ions from cytoplasm. Burkholderia xenovorans strain LB400 has been reported to encode six CHR homologues in its multireplicon genome. We found that strain LB400 displays chromate-inducible resistance to chromate. Susceptibility tests of Escherichia coli strains transformed with cloned B. xenovorans chr genes indicated that the six genes confer chromate resistance, although under different growth conditions, and suggested that expression of chr genes is regulated by sulfate. Expression of chr genes was measured by quantitative reverse transcription-PCR (RT-qPCR) from total RNA of B. xenovorans LB400 grown under different concentrations of sulfate and exposed or not to chromate. The chr homologues displayed distinct expression levels, but showed no significant differences in transcription under the various sulfate concentrations tested, indicating that sulfate does not regulate chr gene expression in B. xenovorans. The chrA2 gene, encoded in the megaplasmid, was the only chr gene whose expression was induced by chromate and it was shown to constitute the chromate-responsive chrBACF operon. These data suggest that this determinant is mainly responsible for the B. xenovorans LB400 chromate resistance phenotype.
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Escudero-Castejon, Lidia, Sergio Sanchez-Segado, Stephen Parirenyatwa et Animesh Jha. « Formation of Chromium-Containing Molten Salt Phase during Roasting of Chromite Ore with Sodium and Potassium Hydroxides ». Journal for Manufacturing Science and Production 16, no 4 (1 décembre 2016) : 215–25. http://dx.doi.org/10.1515/jmsp-2016-0023.

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AbstractChromium has a wide range of applications including metals and alloys manufacturing, pigments, corrosion resistance coatings and leather tanning. The production of chromium chemicals is based on the oxidative alkali roasting of chromite ores, which leads to the formation of water-soluble alkali chromates. Previous investigations reported that when chromite is roasted with soda-ash, a molten salt containing chromium, which is mainly composed of sodium carbonate and sodium chromate (Na2CO3-Na2CrO4 binary mixture), forms under typical roasting conditions. The physical properties of the liquid phase, which are dependent on the temperature, charge and gangue compositions, play an important role on the oxidation reaction and may limit the chromate recovery by hindering the oxygen transport to the reaction interface. This investigation focuses on the alkali roasting of chromite ore at 1,000 oC using NaOH and KOH, followed by water leaching. The influence of the alkali ratio on the chromium extraction yield is analysed, and the results obtained with both hydroxides are compared. Sample characterisation and thermodynamic analysis, including phase diagrams, equilibrium calculations and computation of liquidus curves, are combined with the purpose of studying the formation of the molten salt phase under different roasting conditions and its effect on the final chromium recovery.
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Cervantes, Carlos, et Hisao Ohtake. « Plasmid-determined resistance to chromate inPseudomonas aeruginosa ». FEMS Microbiology Letters 56, no 2 (décembre 1988) : 173–76. http://dx.doi.org/10.1111/j.1574-6968.1988.tb03172.x.

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Guo, Rui Hua, Fang Sheng Liu et Lin Min Wang. « Research of Anti-Corrosion of Armour Steel in Surface Chromate Conversion Coating ». Advanced Materials Research 734-737 (août 2013) : 2332–37. http://dx.doi.org/10.4028/www.scientific.net/amr.734-737.2332.

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This article by orthogonal experimental method to determine the composition of chromate conversion and use of electrochemical method of electrochemical corrosion of the film discussed the substrate in different components, content, time and pH of chromate conversion coating of corrosion resistance. Orthogonal to determine the best experimental chromate conversion solution by adding the rare earth element cerium and lanthanum salt, and discuss the effects of rare earth elements cerium and lanthanum chromate conversion film on the anti-corrosion. The results show that in CrO3 5.4 g/L, NaF 0.5 g/L, K3Fe (CN)6 0.5 g/L, pH 1, conversion time is three minutes, there is a better corrosion resistance. The rare earth elements in a chromate conversion solution, La2(CO3)3 to 0.2 g/L chromate conversion coating of the anti-corrosion better.
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Branco, Rita, Ana Paula Chung, Tatiana Johnston, Volkan Gurel, Paula Morais et Anatoly Zhitkovich. « The Chromate-Inducible chrBACF Operon from the Transposable Element TnOtChr Confers Resistance to Chromium(VI) and Superoxide ». Journal of Bacteriology 190, no 21 (5 septembre 2008) : 6996–7003. http://dx.doi.org/10.1128/jb.00289-08.

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ABSTRACT Large-scale industrial use of chromium(VI) has resulted in widespread contamination with carcinogenic chromium(VI). The abilities of microorganisms to survive in these environments and to detoxify chromate require the presence of specific resistance systems. Here we report identification of the transposon-located (TnOtChr) chromate resistance genes from the highly tolerant strain Ochrobactrum tritici 5bvl1 surviving chromate concentrations of >50 mM. The 7,189-bp-long TnOtChr of the mixed Tn21/Tn3 transposon subfamily contains a group of chrB, chrA, chrC, and chrF genes situated between divergently transcribed resolvase and transposase genes. The chrB and chrA genes, but not chrF or chrC, were essential for establishment of high resistance in chromium-sensitive O. tritici. The chr promoter was strongly induced by chromate or dichromate, but it was completely unresponsive to Cr(III), oxidants, sulfate, or other oxyanions. Plasmid reporter experiments identified ChrB as a chromate-sensing regulator of chr expression. Induction of the chr operon suppressed accumulation of cellular Cr through the activity of a chromate efflux pump encoded by chrA. Expression of chrB, chrC, or chrF in an Escherichia coli sodA sodB double mutant restored its aerobic growth in minimal medium and conferred resistance to superoxide-generating agents menadione and paraquat. Nitroblue tetrazolium staining on native gels showed that ChrC protein had superoxide dismutase activity. TnOtChr appears to represent a mobile genetic system for the distribution of the chromate-regulated resistance operon. The presence of three genes protecting against superoxide toxicity should provide an additional survival advantage to TnOtChr-containing cells in the environments with multiple redox-active contaminants.
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Thèses sur le sujet "Chromate resistance"

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Gordon, Matthew. « A Nacreous Self-Assembled Nanolaminate for Corrosion Resistance on 2024-Al Alloy ». Thesis, Virginia Tech, 2001. http://hdl.handle.net/10919/33548.

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Nanometer thick layers of clay and polymer were formed on mica, silicon, and aluminum 2024-T3 alloy using alternating solutions of positively and negatively charged polymer and clay, respectively. Atomic force microscopy was used to observe the morphology of the composite films on mica and silicon. It was found that solution concentrations of clay above 0.02 weight percent lead to the uncontrolled deposition of clay platelets on the substrateâ s surface. By using solution concentrations of clay above 0.02 weight percent and ultrasonic agitation together it is possible to deposit a uniform monolayer of clay platelets on a mica substrate in £ 20 seconds. Ultrasonic agitation also produced crude patterns of montmorillonite platelets. Thin films of poly(diallydimethylammonium chloride) (PDDA) were made using concentrations ³ 2 weight percent of PDDA. It was found that the PDDA formed several unusual morphologies. Spherulites of PDDA were observed with AFM and the glass transition temperature of high molecular weight PDDA was measured using differential scanning calorimetry (DSC). Circular regions of positive charge were discovered on silicon wafers provided by three different sources. These areas of charge have never been reported in literature, but can easily be detected by placing wafers into solutions containing negatively or positively charged solutions of clay or polymer, respectively. The exact nature of these charged regions is unknown, but it is hypothesized that impurities on silicon wafers create the circular regions of positive charge. ISAM films made of a polyamide salt and a synthetic clay, Laponite RD®, demonstrated significant corrosion resistance on 2024-T3 Al alloys after 168 hours of salt spray testing. The ISAM films offered corrosion protection only if there was a significant layer of underlying surface oxide present, however. It was found that ISAM deposited films of polyarylic acid (PAA) and polyallylamine hydrochloride (PAH) may offer some corrosion resistance on 2024-T3 Al alloys, but these filmsâ corrosion resistance is severely hampered by the presence of Cl- in the PAH solution. Funding from this project was gratefully received from the Materials Science and Engineering Department at Virginia Tech; Luna Innovations Inc; the American Chemical Society / Petroleum Research Fund #34412-G5 and the Environmental Protection Agency Contract #68-D-00-244.
Master of Science
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Krejčířová, Dana. « Pasivace hořčíkových slitin ». Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2008. http://www.nusl.cz/ntk/nusl-216369.

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Diploma thesis deals with the technology of surface modifications of magnesium alloys. Basic knowledge from the field of the corrosion of metal materials. The division corrosion according to way of attack and corrosion environment, etc. There is an enumeration of ways of the corrosion defence. Questions of surface modifications with an emphasis on passivation by conversion coating and its analysis. Characteristics of magnesium and its alloys. Magnesium alloys with lithium, possibilities of its passivation and the verification of corrosion resistance. Enumeration of the used devices, chemicals and materials. characteristics of the used alloys. creation of the corrosion resistance standard. Research in passivation on the alloy containing 12 percent of lithium. The verification of the corrosion test usability based on the suggestion of the background research results. The test results for passivated as well as untreated samples and the reference material (steel). Aplication of chromate-free passivation and corrosion test on the alloy containing 12 percent of lithium.
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He, Minyan, Xiangyang Li, Liang Guo, Susan Miller, Christopher Rensing et Gejiao Wang. « Characterization and genomic analysis of chromate resistant and reducing Bacillus cereus strain SJ1 ». BioMed Central, 2010. http://hdl.handle.net/10150/610053.

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BACKGROUND:Chromium is a toxic heavy metal, which primarily exists in two inorganic forms, Cr(VI) and Cr(III). Chromate Cr(VI)] is carcinogenic, mutational, and teratogenic due to its strong oxidizing nature. Biotransformation of Cr(VI) to less-toxic Cr(III) by chromate-resistant and reducing bacteria has offered an ecological and economical option for chromate detoxification and bioremediation. However, knowledge of the genetic determinants for chromate resistance and reduction has been limited so far. Our main aim was to investigate chromate resistance and reduction by Bacillus cereus SJ1, and to further study the underlying mechanisms at the molecular level using the obtained genome sequence.RESULTS:Bacillus cereus SJ1 isolated from chromium-contaminated wastewater of a metal electroplating factory displayed high Cr(VI) resistance with a minimal inhibitory concentration (MIC) of 30 mM when induced with Cr(VI). A complete bacterial reduction of 1 mM Cr(VI) was achieved within 57 h. By genome sequence analysis, a putative chromate transport operon, chrIA1, and two additional chrA genes encoding putative chromate transporters that likely confer chromate resistance were identified. Furthermore, we also found an azoreductase gene azoR and four nitroreductase genes nitR possibly involved in chromate reduction. Using reverse transcription PCR (RT-PCR) technology, it was shown that expression of adjacent genes chrA1 and chrI was induced in response to Cr(VI) but expression of the other two chromate transporter genes chrA2 and chrA3 was constitutive. In contrast, chromate reduction was constitutive in both phenotypic and gene expression analyses. The presence of a resolvase gene upstream of chrIA1, an arsenic resistance operon and a gene encoding Tn7-like transposition proteins ABBCCCD downstream of chrIA1 in B. cereus SJ1 implied the possibility of recent horizontal gene transfer.CONCLUSION:Our results indicate that expression of the chromate transporter gene chrA1 was inducible by Cr(VI) and most likely regulated by the putative transcriptional regulator ChrI. The bacterial Cr(VI)-resistant level was also inducible. The presence of an adjacent arsenic resistance gene cluster nearby the chrIA1 suggested that strong selective pressure by chromium and arsenic could cause bacterial horizontal gene transfer. Such events may favor the survival and increase the resistance level of B. cereus SJ1.
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Amalraj, James. « Gene Regulation Associated with IFN-Resistance Mechanisms in Melanoma ». Thesis, Griffith University, 2012. http://hdl.handle.net/10072/366926.

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Melanoma is the most aggressive form of skin cancer with rapidly increasing rates of incidence in fair-skinned populations worldwide. The most promising current treatment for advanced stage melanoma involves a combination of chemotherapy and interferon alpha (IFN-α), although complete response rates are unacceptably low. Loss of sensitivity to IFNs in melanoma cells has been shown to arise from a deficiency in the level of intracellular signalling molecules including STAT1, STAT2 & IRF9, which are important transcription factors in the IFN signalling pathway. Of these, deficiencies in STAT1 show the greatest correlation with IFN resistance. Greater understanding of the regulation of STAT1 gene transcription is important for predicting, and potentially improving, IFN mediated activity in malignant melanomas. In a previous study, distinct enhancer and repressor regions were shown to be present in the first and second introns of the human STAT1 gene. A gene segment comprising 123 base pairs located in the second intron was shown to confer specific repression of reporter gene constructs in melanoma cell lines. Within this regulatory region, we have identified a putative repressor element-1 (RE1) site, and shown binding of the RE1 silencer of transcription (REST) protein in melanoma cell lines by chromatin immunoprecipitation (ChIP) assays. In transient transfection assays, a luciferase gene reporter construct comprising the RE1 sequence from the STAT1 gene cloned immediately downstream of the STAT1 promoter and enhancer regions exhibited significant repression of reporter gene activity. Furthermore, progressively stronger repression was conferred by cloning tandem copies of the STAT1-RE1 sequence adjacent to the promoter/enhancer region, confirming the repressive activity of this element. The partial loss of repression of the STAT1 promoter by the RE1 element in a cell line expressing a low level of the REST protein further confirmed the functional significance of REST and the RE1 element within the STAT1 gene.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Medical Science
Griffith Health
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Johnson, Sarah Elizabeth. « An Investigation into the Acetylation of the Lyase Domain of DNA Polymerase \(\beta\) and Chromatin Structure Confers Cellular Resistance to MMS ». Thesis, Harvard University, 2011. http://dissertations.umi.com/gsas.harvard:10038.

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The methyltranferases Suv39h1 and Suv39h2 place the trimethyl mark on lysine 9 of histone H3 (H3K9me3). Heterochromatin Protein 1 (HP1) interacts with H3K9 through its chromodomain (Nielsen et al., 2001). Kap-1, another heterochromatin associated protein interacts with HP1, and together they help to form the compact heterochromatin structure. Without these methyltransferases, cells have less heterochromatin and increased genomic instability (Peters et al., 2001). Previous work in our lab (unpublished) showed that cells lacking these enzymes were more sensitive to ionizing radiation than wild type cells. This indicated a defect in double strand break repair. We wanted to ask if these cells were also more sensitive to methylating agents that cause damage that is repaired through the BER pathway. We found that cells lacking the Suv39h2 methyltransferase treated with MMS, a methylating agent, were more resistant to methylation damage than the wild type. We also wanted to ask whether Kap-1, a heterochromatin associated protein that interacts with the Suv39h1/2 methyltransferases, was phosphorylated after MMS treatment. We found ATM dependent phosphorylation of Kap-1, indicating that cells had relaxed chromatin after treatment with MMS. We hypothesize that this relaxation of chromatin gives the cells resistance to MMS as it allows for easier repair without the need for chromatin remodeling.
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Molin, Denis. « Next generation multimode fiber for high speed data networks with improved bend resistance and chromatic dispersion compensation ». Thesis, Lille 1, 2016. http://www.theses.fr/2016LIL10046.

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Les premières fibres optiques, développées dans les années 70, étaient multimodes. Le profil d’indice de type « saut d’indice » originel a rapidement cédé la place aux profils « à gradient d’indice », présentant une bande passante plus large. Malgré une bande passante plus faible, dû à la dispersion modale, les fibres multimodes (MMFs) ont su rester compétitives face aux fibres monomodes sur des applications utilisant des sources à grande ouverture numérique : grâce à leurs large cœur et grande ouverture numérique, elles sont plus tolérantes au désalignement source-fibre et fibre-fibre. Cette thèse entre dans le cadre du développement des MMFs pour les télécommunications, dans les réseaux locaux et les centres de données. Les sources optiques à base de diode laser à cavité verticale émettant par la surface disponibles depuis le début des années 2000 ont fait entrer les MMFs dans l’ère du multi-gigabit par seconde. Cette technologie a abouti à la standardisation des fibres OM3 en 2002 suivies des fibres OM4 (à la bande-passante modale plus de 2 fois plus large) en 2009, dont la bande passante modale est maximisée à 850nm. Ce travail présente les développements des fibres multimodes OM3 et OM4 de ces dix dernières années. Il se décompose en trois axes : i) l’optimisation de profil d’indice pour augmenter la bande passante modale des MMFs (développement des fibres OM4), ii) la minimisation des pertes par courbures des fibres OM3 et OM4 (développement de fibres OM4 résistantes à la courbure),iii) l’étude de la compensation de la dispersion chromatique dans les MMFs utilisées avec des VCSEL multimodes transverses, qui ouvre la voie à de nouvelles possibilités d’optimisation
Multi-Mode Fibers (MMFs) were the first optical fibers to be developed in the early days of optical communications, before the advent of Single-Mode Fibers (SMFs). Graded-Index MMFs (GI-MMFs) were rapidly introduced to reduce the modal dispersion, and thus enlarge the modal bandwidth, that limited the capacity of original Step-Index fibers (SI-MMFs), paving the way to short-range high-speed optical transmissions. Their typical large core and high numerical aperture provide significant advantages over SMFs in applications that require efficient light coupling with large sources and relaxed fiber alignment tolerances. MMFs are used in many fields such as industry, defense, transport, telecommunications and medical. This work focuses on the application for which MMFs are the most widely used nowadays, that is data communications. MMFs have constantly evolved and improved to keep up to pace. The advent of low-cost and low-power-consuming directly current-modulated VCSELs that can reliably support 10Gbps (and more) data rates at ~850nm has motivated the development and the standardization of laser-launch optimized 50µm-diameter GI-MMFs: the OM3 fibers (2002) and the OM4 fibers (2009). We present here the OM3 and OM4 fiber development for the last decade we divided into three main topics:i) the optimization of the refractive index profile to maximize the modal bandwidth (development of the OM4 fiber),ii) the minimization of the macrobending losses (development of so-called bend-insensitive OM4 fibers),iii) the chromatic dispersion compensation to ultimately enlarge the total bandwidth of MMFs, accounting for modal and chromatic dispersions and their interaction
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Chriett, Sabrina. « Epigenetic regulations by insulin and histone deacetylase inhibitors of the insulin signaling pathway in muscle ». Thesis, Lyon, 2016. http://www.theses.fr/2016LYSE1167/document.

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L’émergence et le développement des maladies métaboliques est sous le contrôle de multiples facteurs génétiques et environnementaux. Le diabète et la résistance à l’insuline sont des maladies métaboliques caractérisées par des défauts dans la sécrétion de l’insuline ou son utilisation périphérique, ou les deux. L’insuline est l’hormone clé de l’utilisation du glucose, et régule également transcriptionnellement et épigénétiquement l’expression des gènes.En travaillant sur le muscle, l’implication de l’épigénétique dans la régulation de l’expression des gènes de la voie de l’insuline a été mis en évidence. L’hexokinase 2 (HK2) est régulée par l’insuline et participe au métabolisme glucidique. Le rôle de l’épigénétique y est démontré avec l’augmentation de l’acétylation des histones autour du site d’initiation de la transcription (SIT) de HK2 et l’accumulation d’une isoforme permissive des histones, H2A.Z. Ces deux phénomènes sont le signe d’une transcription permissive.Nous avons ensuite étudié le rôle de l’acétylation des histones dans les régulations amenées par l’insuline dans les myotubes L6. Nous avons utilisé le butyrate, un inhibiteur des histones deacetylase (HDACi), dans un contexte d’insulino-résistance induite par une lipotoxicité. Le butyrate a en partie restauré la sensibilité à l’insuline visible au niveau des phosphorylations de la PKB (protein kinase B) et de la MAPK (Mitogen-activated protein kinase), inhibées par le traitement au palmitate. Le butyrate a augmenté l’expression de l’ARNm et de la protéine d’IRS1. La surexpression génique d’IRS1 est épigénétique-dépendante car liée à une augmentation de l’acétylation des histones au SIT d’IRS1.L’ensemble de ces résultats démontre l’existence d’un lien entre les modifications épigénétique et l’action de l’insuline. Cela suggère qu’une intervention pharmacologique sur la machinerie épigénétique pourrait être un moyen d’améliorer le métabolisme, et l’insulino-résistance
Diabetes and insulin resistance are metabolic diseases characterized by altered glucose homeostasis due to defects in insulin secretion, insulin action in peripheral organs, or both. Insulin is the key hormone for glucose utilization and regulates gene expression via transcriptional and epigenetic regulations.We determined the epigenetic implications in the regulation of expression of insulin signaling pathway genes. Hexokinase 2 (HK2) is known to be upregulated by insulin and directs glucose into the glycolytic pathway. In L6 myotubes, we demonstrated that insulin-induced HK2 gene expression rely on epigenetic changes on the HK2 gene, including an increase in histone acetylation around the transcriptional start site (TSS) of the gene and an increase in the incorporation of the histone H2A.Z isoform – a histone variant of transcriptionally active chromatin. Both are epigenetic modifications compatible with increased gene expression.To elucidate the role of histone acetylation in the regulation of insulin signaling and insulin-dependent transcriptional responses in L6 myotubes, we investigated the effects of butyrate, an histone deacetylase inhibitor (HDACi), in a model of insulin resistance induced by lipotoxicity. Butyrate partly alleviated palmitate-induced insulin resistance by ameliorating insulin-induced PKB (protein kinase B) and MAPK (Mitogen-activated protein kinase) phosphorylations, downregulated with exposure to palmitate. Butyrate induced an upregulation of IRS1 gene and protein expression. The transcriptional upregulation of IRS1 was proven to be epigenetically regulated, with butyrate promoting increased histone acetylation around the TSS of the IRS1 gene.These results support the idea of the existence of a link between epigenetic modifications and insulin action. Pharmacological targeting of the epigenetic machinery might be a new approach to improve metabolism, especially in the insulin resistant condition.Key words: Muscle, insulin resistance, epigenetic, chromatin, histone acetylation, histone deacetylase inhibitor (HDACi), butyrate, palmitate
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Holl, Hugo J. « An evaluation of the strategies used to reduce resistance to change during business reengineering in Samancor Chrome ». Thesis, Stellenbosch : Stellenbosch University, 2000. http://hdl.handle.net/10019.1/51600.

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Thesis (MBA)--Stellenbosch University, 2000.
ENGLISH ABSTRACT: Samancor Chrome is an integrated ferrochrome producer with an estimated annual ferrochrome capacity of 1.26 million tons, or approximately twenty-five per cent of total Western world capacity in 1997. A decline in commodity pricing and other factors prompted Samancor to initiate a business process reengineering (BPR) programme facilitated by McKinsey and Company in the Chrome Alloys Division in 1997. The process however, met with considerable resistance from the Unions within Samancor Chrome, although several strategies were employed to promote acceptance of the process. The technical report assesses the effect of strategies utilised to lessen resistance to change during the business process reengineering programme initiated in Samancor Chrome. The assessment reviewed strategies given in relevant literature to lessen resistance to business reengineering processes and considered the applicability of such strategies within the context of Samancor Chrome. Research data was obtained through semi-structured interviews with Samancor Chrome senior management. The research showed that Samancor Chrome had formulated a communication and a participation strategy in preparation of the BPR programme. The strategies were the only acceptance strategies suggested by McKinsey and Company in their role as the BPR consultants. The context provided by the literature research showed that the participation strategy and the formulation of the communication strategy were inappropriate within the organisational context of Samancor Chrome. Conclusions regarding the situational validity of the strategies were supported by the failure of the strategies to reduce resistance against the BPR programme. A negotiation strategy was ultimately used as an acceptance strategy during the BPR programme, and contextual analysis showed the strategy to be appropriate although only partially effective as implementation was still delayed. Interpretative analysis of the research data indicated that a change management strategy for future BPR initiatives should rather contain elements of education, communication, retrenchment avoidance measures and consultation or negotiation within a management led, top-down approach. Management should drive the BPR process in an emphatic manner, with the programme execution and implementation being completed within a four to six month short time frame.
AFRIKAANSE OPSOMMING: Samancor Chroom is 'n ge-integreerde ferrochroom produsent met 'n geskatte kapasiteit van 1.26 miljoen ton per annum, of ongeveer vyf en twintig persent van die totale Westerse wêreld kapasiteit in 1997. 'n Reële verlaging in kommoditeits pryse sowel as ander faktore het daartoe gelei dat Samancor Chroom in 1997 'n besigheids proses herontwerp oefening onder leiding van McKinsey and Company in die Chroom Allooi Divisie geinisieer het. Die proses is egter deur die Unies binne Samancor weerstaan, alhoewel verskeie strategieë gebruik was om aanvaarding van die proses te bewerkstellig. Die tegniese verslag evalueer die effektiwiteit van die strategieë wat toegepas was om weerstand teen verandering tydens die besigheids proses herontwerp (BPH) in Samancor Chroom te verminder. Die evaluasie neem ook strategieë vanuit toepaslike literatuur om weerstand tydens besigheids proses herontwerp programme te verminder in ag, en oorweeg die toepaslikheid van die strategieë in die konteks van Samancor Chroom. Navorsings inligting is ingesamel deur semi-gestruktureerde onderhoude met Samancor senior bestuurs personeel. Die navorsing dui daarop dat Samancor Chroom kommunikasie en deelnemenings strategieë in voorbereiding vir die BPH program ontwikkel het. Die strategieë was ook die enigste strategieë wat deur McKinsey and Company in hul rol as BPH konsultante voorgestel was. Die konteks deur die literatuur studie geskep, het aangedui dat die deelnemings strategie sowel as die formulering van die kommunikasie strategie onvanpas was binne die organisatoriese konteks van Samancor Chroom. Gevolgtrekkings aangaande die situasionele validiteit van die strategieë was ondersteun deur die faling van die strategieë om weerstand teen die BPH program te verminder. 'n Onderhandelings strategie is uiteindelik as 'n aanvaardings strategie tydens die BPH program toegepas, en konteks analise dui die strategie as toepaslik aan alhoewel slegs gedeeltelik suksesvol, aangesien die program implementasie vertraag was. Interpretiewe analise van die navorsings inligting dui aan dat 'n veranderings strategie vir toekomstige BPH initiatiewe elemente van opleiding, kommunikasie, inkorting vermyding maatreëls en konsultasie of onderhandeling binne 'n bestuurs gedrewe program benadering moet bevat. Die program moet sonder vertraging gedryf word, met program voltooing en implementering tussen vier tot ses maande.
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Miller, Robert B. II. « Chromium (VI) Reduction by Shewanella oneidensis MR-1 in Elevated Chromium Concentrations Exhibited in Corrosion Resistant Coatings ». University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1398095549.

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Erramouspe, Pasilio Pablo Joaquin. « The Facilitates Chromatin Transcription (FACT) complex as a novel target for the treatment of Neuroendocrine Prostate Cancer ». Thesis, Queensland University of Technology, 2022. https://eprints.qut.edu.au/229973/1/Pablo%20Joaquin_Erramouspe%20Pasilio_Thesis.pdf.

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This thesis is about the role of The Facilitates Chromatin Transcription (FACT) complex as a potential target for Neuroendocrine Prostate Cancer (NEPC). I studied FACT complex in different models representing the main stages of prostate cancer progression and found that FACT complex expression correlated to the lethal NEPC phenotype. The FACT-inhibiting drug, CBL1037, was more effective at reducing cell viability as compared to the standard-of-care chemotherapy drugs, cisplatin and carboplatin. Significantly lower dose of CBL0137 was required to achieve 50% cell death. These results are promising and support further investigation of CBL0137 as anti-cancer therapy in late-stage prostate cancer.
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Livres sur le sujet "Chromate resistance"

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Papp, John F. Chromium, nickel, and other alloying elements in U.S.-produced stainless and heat-resisting steel. Washington, D.C. (2401 E St., N.W., MS #9800, Washington 20241-0001) : U.S. Dept. of the Interior, Bureau of Mines, 1991.

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Papp, John F. Chromium, nickel, and other alloying elements in U.S.-produced stainless and heat-resisting steel. [Washington, D.C.] : U.S. Dept. of the Interior, Bureau of Mines, 1988.

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A, Laskowski J., et United States. National Aeronautics and Space Administration., dir. Tribological evaluation of PS300 : A new chrome oxide based solid lubricant coating sliding against A1₂0₃ from 25 to 650⁰C. [Washington, DC] : National Aeronautics and Space Administration, 1996.

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DellaCorte, Christopher. The evaluation of a modified chrome oxide based high temperature solid lubricant - coating for foil gas bearing. [Cleveland, Ohio] : National Aeronautics and Space Administration, Lewis Research Center, 1998.

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Center, Lewis Research, dir. The evaluation of a modified chrome oxide based high temperature solid lubricant - coating for foil gas bearing. [Cleveland, Ohio] : National Aeronautics and Space Administration, Lewis Research Center, 1998.

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Tribological evaluation of PS300 : A new chrome oxide based solid lubricant coating sliding against A1₂0₃ from 25 to 650⁰C. [Washington, DC] : National Aeronautics and Space Administration, 1996.

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Tribological evaluation of PS300 : A new chrome oxide based solid lubricant coating sliding against A1₂0₃ from 25 to 650⁰C. [Washington, DC] : National Aeronautics and Space Administration, 1996.

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Chapitres de livres sur le sujet "Chromate resistance"

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Agarwala, V. S. « Enhancement of Acid-Chloride Resistance in a Chromate Conversion Coating ». Dans Polymeric Materials for Corrosion Control, 211–19. Washington, DC : American Chemical Society, 1986. http://dx.doi.org/10.1021/bk-1986-0322.ch019.

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Gadaleta, Raffaella Maria, et Luca Magnani. « Chromatin and Epigenetic Determinants of Resistance to Aromatase Inhibitors ». Dans Resistance to Targeted Anti-Cancer Therapeutics, 145–68. Cham : Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17972-8_8.

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Sulewski, Stanley. « Low Metal Marking White Gloss Glaze Resistant to Chrome Fuming ». Dans Whitewares and Materials : Ceramic Engineering and Science Proceedings, Volume 24, Issue 2, 25. Hoboken, NJ, USA : John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470294796.ch3.

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Potter, M., K. K. Sanford, R. Parshad, K. Huppi et B. Mock. « Susceptibility and Resistance to Plasmacytomagenesis : Possible Role of Genes That Modify Efficiency of Chromatin Repair ». Dans Genetics of Immunological Diseases, 289–94. Berlin, Heidelberg : Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-50059-6_43.

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Li, Youqi, Changming Ke, Song Gao, Yanfeng Zhang, Jizeng Zhao et Guotian Ye. « Effects of Zirconia on the Thermal Shock Resistance of High Chrome Refractories for Coal Slurry Gasifier ». Dans Proceedings of the Unified International Technical Conference on Refractories (UNITECR 2013), 1229–34. Hoboken, NJ, USA : John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9781118837009.ch208.

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Bello Minciacchi, Cecilia. « «Il festival rinascerà», Paola Masino inviata alla Manifestazione d’Arte Cinematografica di Venezia del 1946 ». Dans Italianistica. Venice : Fondazione Università Ca’ Foscari, 2020. http://dx.doi.org/10.30687/978-88-6969-422-5/004.

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The essay presents and analyses the film criticism articles written by Paola Masino for the new edition of the Venice Film Festival after the Second World War. The articles, which appeared in the Gazzetta d’Italia between August 31 and September 19, 1946, were not later collected or republished. These are rare materials, never studied before, found among the documents of the Fondo Paola Masino kept at the Archivio del Novecento, Sapienza University of Rome. Other significant and useful information to understand Masino’s critical perspective on cinema emerges from the letters sent from Venice to family members. The analysis of the articles highlights in Paola Masino a lively intellectual curiosity and great precision in aesthetic judgments, in addition to a peculiar sensitivity to chromatic values, and an ethical attention to the political perspective of film directors and to the recent tragedies of war and partisan resistance in Italy. Among the most interesting data emerged from these articles, there are some theoretical reflections on aesthetic principles valid not only for cinema, but for all the arts, including the narrative and the literary work of the same Paola Masino.
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Hentzen, Peter C., et Isaae Bekhor. « Characterization of the 2 M NaCl-Resistant Chromatin Fraction from Chicken Erythroid Cells ». Dans Progress in Nonhistone Protein Research, 75–101. CRC Press, 2018. http://dx.doi.org/10.1201/9781351076067-4.

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Schwarz Schuler, Joao Paulo, Santiago Romani, Mohamed Abdel-Nasser, Hatem Rashwan et Domenec Puig. « Reliable Deep Learning Plant Leaf Disease Classification Based on Light-Chroma Separated Branches ». Dans Frontiers in Artificial Intelligence and Applications. IOS Press, 2021. http://dx.doi.org/10.3233/faia210157.

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The Food and Agriculture Organization (FAO) estimated that plant diseases cost the world economy $220 billion in 2019. In this paper, we propose a lightweight Deep Convolutional Neural Network (DCNN) for automatic and reliable plant leaf diseases classification. The proposed method starts by converting input images of plant leaves from RGB to CIE LAB coordinates. Then, L and AB channels go into separate branches along with the first three layers of a modified Inception V3 architecture. This approach saves from 1/3 to 1/2 of the parameters in the separated branches. It also provides better classification reliability when perturbing the original RGB images with several types of noise (salt and pepper, blurring, motion blurring and occlusions). These types of noise simulate common image variability found in the natural environment. We hypothesize that the filters in the AB branch provide better resistance to these types of variability due to their relatively low frequency in the image-space domain.
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Alves Junior, José Genival, André Pina Moreira, André Neves Lemoine et Clodomir Barros Pereira Junior. « Product Proposal For Restoring Residential Facades In Historical Sites Using A Lime-Based System ». Dans METHODOLOGY FOCUSED ON THE AREA OF INTERDISCIPLINARITY- V1. Seven Editora, 2023. http://dx.doi.org/10.56238/methofocusinterv1-039.

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Historic Urban Centers are important in the new era of the globalized world and the economic development of sustainable tourism. These centers are laden with symbolism and cultural identity. Key elements in the landscape. In this way, to attract visitors, it is essential to preserve the architectural and urban complex. Facade coatings have as their main function the protection of masonry elements. In the context of historic buildings, in addition to protection, the external coating is an integral and inseparable element of the material authenticity of the monument. They are ancestral materials and techniques, in addition to chromatic concepts that, over the years, give it value and coherence within a whole. Based on the aspects described above, the research consists of presenting a lime-based coating system that responds positively to the physical and chemical requirements of old supports, ensuring satisfactory resistance in addition to aesthetic and historical coherence, guaranteeing greater authenticity. , preserving the historical and aesthetic reading of the monument. From the study of building typologies and ancestral construction techniques, combined with the study of mortars, their main characteristics, constituents, and pathologies, it was possible to adopt an experimental trait for the construction of a coating system inspired by ancient constructive practices for mortar coating on facades. Finally, this research describes guidelines for further studies considered necessary for the improvement of this intervention process, which aims to reduce the distortions verified in the current practice of restoring old residential facades located in the Historic Site of Olinda.
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Actes de conférences sur le sujet "Chromate resistance"

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Wang, Frank Fan. « An Innovative Way to Solve Problems Associated With Circular Connector Electrical Bonding Resistance ». Dans ASME 2013 International Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Microsystems. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/ipack2013-73029.

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Cadmium plated circular connectors and chromate conversion coated aluminum chassis are widely used on electronic equipment for both civilian and military aerospace applications. This article discusses electrical bonding resistance problems associated with cadmium plated circular connectors and chromate conversion coated aluminum chassis and proposes an innovative way to solve that problem.
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Yamazaki, Etsuko, Toshiyuki Uehara et Chizuko Yoshida. « Development of Heat Exchangers with Non-Chromate High Corrosion Resistance Treatment ». Dans SAE 2000 World Congress. 400 Commonwealth Drive, Warrendale, PA, United States : SAE International, 2000. http://dx.doi.org/10.4271/2000-01-0572.

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Watanabe, Haruyuki, Masahiro Oshio et Naohiro Kunieda. « Variation in Corrosion Resistance of Trivalent Chromate Coating Depending on Type of Zinc Plating Bath ». Dans SAE 2006 World Congress & Exhibition. 400 Commonwealth Drive, Warrendale, PA, United States : SAE International, 2006. http://dx.doi.org/10.4271/2006-01-1671.

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Teratani, T., T. Suidzu, K. Tani et Y. Harada. « Strengthening Alumina Protective Layer on MCrAlY Atmospheric Plasma Sprayed Coating by Chromate Processing ». Dans ITSC2004, sous la direction de Basil R. Marple et Christian Moreau. ASM International, 2004. http://dx.doi.org/10.31399/asm.cp.itsc2004p0918.

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Abstract The high temperature oxidation resistance behavior of atmospheric plasma sprayed CoNiCrAlY coating with a thin layer of Cr2O3 employing chromate treatment was investigated. The high-temperature oxidation test was performed at 1423K for 7.2, 14.4 and 32.4ks, respectively. The formation of the oxide layer on the CoNiCrAlY coatings with Cr2O3 thin layer by chromate treatment was compared with that of the non-Cr2O3 thin layer. The oxide layer formed on the both types of MCrAlY coatings grows with increasing the elevated temperature and the holding time. Also, the thickness of the oxide layers was proportional to the square root of time. The thickness of the oxide layer on CoNiCrAlY coatings with the thin layer of Cr2O3 was only 60% as compared with that of the non-Cr2O3 thin layer in high temperature oxidation tests at 1423K.
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Choi, Alexander, Tyler Luneski, Zbigniew M. Bzymek, Vito Moreno et Geri Gonxhe. « A Search for Optimal Friction Resistant Material to Cover Contact Surfaces : A Case Study in the Senior Mechanical Engineering Design Student Project ». Dans ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-65481.

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The University of Connecticut Department of Mechanical Engineering has developed an industry recognized Senior Design Capstone course that provides students the opportunity for a major design experience. This paper will discuss the issues and challenges associated with project demonstrated on the base of the Search for Optimal Friction Resistant Material to Cover Contact Surfaces in an Electric Manual Switch. In order to determine the viability of potential substitute materials, the team produced custom testing rigs to evaluate material wear and corrosion performance. The construction of these rigs, the fabrication of the testing coupons, testing results and the final choice of the covering material were the primary deliverables of this project. The wear rig allowed the team to determine mechanical performance on the basis of mass loss. In the evaluation of mechanical performance, the coated test coupons were revolved on a testing plate while a flat coated column contacted the surface to wear the plating. After a certain number of cycles, the coupons were subjected to environmental testing. The corrosion rig was designed to provide aggressive corrosion on the worn coupons, and was modeled after the industry standard salt fog test. The worn test coupons were immersed in a humid salt fog test chamber and held at temperature until corroded. A series of calibration checks were completed to evaluate the UConn test severity to ASTM (American Society of Testing Materials) standard testing. The surfaces before and after the corrosion process were analyzed in a number of ways. Optical microscopy, profilometry, and surface metrology techniques were employed to determine which platings were likely to meet the consumer standards necessary for replacement. The large set of data on volume loss, mass loss, and surface degradation provided good metrics for the evaluation of material suitability. The project described in this paper is based on the contribution of the students’ team as well as is the result of consulting effort of the faculty who were directly involved in the course and also the other department’s faculty who were consulting the detail processes. General Electric (GE) especially its Industrial Solution Division that sponsored the project, is a company that provides a wide variety of services in electrical appliances, power, and home and business solutions. It has tasked the team with identifying a suitable replacement for Hexavalent Chromium Chromate passivation. This material is plated on many components in GE electrical appliances due to its resistance to abrasion and corrosion. However, because of changing regulations and the health risks that come from dealing with HCC, the sponsor has determined that it is necessary to remove the plating from production by 2019. In order to determine the viability of potential substitute materials, the team produced custom testing rigs to evaluate material wear and corrosion performance. The construction of these rigs and the fabrication of the 400+ testing coupons, the environmental and mechanical tests results and the final conclusions were the primary deliverables of this project. The team examined three different plating materials (JS 600, trivalent chrome, and zinc phosphate) and compared their performance to that of the original HCC plating. The resulting comparative analysis drove the final recommendation of the best candidate material for the sponsor on the basis of mechanical and environmental performance.
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Shmyreva, T., D. Wang et R. Thorpe. « Relationship of Corrosion Resistance–Coating Structure of HP/HVOF Carbide and Metallic Coatings ». Dans ITSC2001, sous la direction de Christopher C. Berndt, Khiam A. Khor et Erich F. Lugscheider. ASM International, 2001. http://dx.doi.org/10.31399/asm.cp.itsc2001p1143.

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Abstract A study was carried out on the corrosion resistance of the JP- 5000 coatings of Superalloy 625, WC-12%Co, WC-17%Co, WC-10%Co-4%Cr and Cr3C2-25NiCr materials and comparisons made with chrome plating. The coating corrosion resistance was evaluated using the standard salt fog test (ASTM B117) and also by submersion tests in 10% FeCl3 solution (ASTM G48), in 10% HNO3 and in 0.1M H2SO4 + 0.2M HCl solutions. The coating corrosion mechanisms in relationship with the coating microstructure and phase constitutions are discussed. The test results show that the HP/HVOF coating corrosion resistance can be significantly improved through spray parameters and coating structure optimization. All coatings tested herein having optimum microstructure and phase constitutions have shown improved corrosion resistances in comparison with chrome plating.
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Akram, Waseem, Abdul Mateen, Ibrahim Qazi et Ali Hussain. « Development and characterization of cost effective wear and corrosion resistant HVOF sprayed chromite coatings and hard chrome plating ». Dans 2019 16th International Bhurban Conference on Applied Sciences and Technology (IBCAST - 2019). IEEE, 2019. http://dx.doi.org/10.1109/ibcast.2019.8667168.

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Legoux, J. G., S. Bouaricha et P. Marcoux. « Abrasion and Erosion Behavior of WC and CrC Cermet Coatings ». Dans ITSC2004, sous la direction de Basil R. Marple et Christian Moreau. ASM International, 2004. http://dx.doi.org/10.31399/asm.cp.itsc2004p1040.

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Abstract The abrasion and erosion resistance of six different coatings were evaluated in relation to their microstructure. The coatings were produced from six different powders: four containing WC and two containing CrC. Microstructural analysis highlights the relationship between the starting powder morphology and chemistry and the spray conditions in the development of the final coating microstructure. The wear performance of the coatings was evaluated according to the ASTM G-65 standard for the abrasion resistance and a slurry containing 0.66% of 180 μm alumina particles flowing at 20 m/s for wet erosion resistance. The results show that for all tested coatings the abrasion wear resistance is mostly governed by the hardness distribution. For the chrome carbide, coatings having the lowest hardness are the lest abrasion resistant. For the WC containing coatings, carbide debonding and pullout is the main wear mechanisms. The most resistant material being the WC-6Co-8Cr. All the coatings performed better than the D2 tool steel reference sample. The erosion wear resistance is controlled by the local hardness, the matrix properties and the droplet debonding. The most wear-resistant materials are the WC-Co-Cr cermets. The least wear-resistant materials are the clad CrC-20(NiCr) and the WC-Ni cermets.
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Averina, Julia, Galina Kalyakina, Veniamin Boldyrev, Alexander Cherednichenko et Evgenia Rybina. « RESEARCH OF WEAR RESISTANCE OF CHROME DIAMOND COATING ». Dans METAL 2020. TANGER Ltd., 2020. http://dx.doi.org/10.37904/metal.2020.3556.

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Deng, C., K. Zhou, M. Liu, J. Song et C. Wu. « Impingement Resistance of HVAF WC-based Coatings ». Dans ITSC2007, sous la direction de B. R. Marple, M. M. Hyland, Y. C. Lau, C. J. Li, R. S. Lima et G. Montavon. ASM International, 2007. http://dx.doi.org/10.31399/asm.cp.itsc2007p0911.

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Abstract HVO/AF (High-Velocity-Oxygen/Air-Fuel) WC-17Co and WC-10Co4Cr coatings exhibit great potential in the replacement of electrolytic hard chrome (EHC) coating, and comprehensive properties of such coatings should be not worse than those of electrolytic hard chrome coating. The impingement-resistance of HVAF coatings sprayed on 300M ultra-high strength steel was studied in this paper. As an important property index, the fracture toughness of HVAF WC coatings was measured using micro-indentation method at the load of 9.8, 19.6, 24.5, 29.4 and 49.0N respectively. The cracks resulted from stress concentration in the micro-indentation were analyzed. The impingement-resistance for two HVAF WC coatings and EHC was evaluated according to the ASTM D3170 standard, and steel ball dropping experimentation was performed at the height of 0.61, 1.52, 1.83, 2.36 and 2.59m respectively. The cracks caused by both impingements were analyzed using SEM and optical microscopy in comparison with cracks in micro-indentation test.
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Rapports d'organisations sur le sujet "Chromate resistance"

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Watanabe, Haruyuki. Corrosion Resistance of Trivalent Chromate Film by Difference of Plating Bath Kind. Warrendale, PA : SAE International, septembre 2005. http://dx.doi.org/10.4271/2005-08-0534.

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Buchheit, R. G., C. A. Drewien, M. A. Martinez et G. E. Stoner. Chromate-free corrosion resistant conversion coatings for aluminum alloys. Office of Scientific and Technical Information (OSTI), mars 1995. http://dx.doi.org/10.2172/28379.

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