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Wu, Peng, et Jieyun Feng. « Communication research methods - by Guoming Chen, Wenzheng Peng, Yinjiao Ye, and Ran An ». Journal of Communication 63, no 1 (24 janvier 2013) : E3—E6. http://dx.doi.org/10.1111/jcom.12013.
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(C.M.) Kao, Jimmy, et Ran Chen. « Editorial [ Frontier of Nanoscience and Technology (Guest Editors : Chen Ran and Jimmy (C.M.) Kao)] ». Current Nanoscience 8, no 1 (1 février 2012) : 1–2. http://dx.doi.org/10.2174/1385272811208010003.
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Larson, Wendy. « Women and the Discourse of Desire in Postrevolutionary China : The Awkward Postmodernism of Chen Ran ». boundary 2 24, no 3 (1997) : 201. http://dx.doi.org/10.2307/303713.
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최은정. « The Absence of Father and the daughter’ growth - Focusing on Chi li, Chen ran, Hong ying's works ». Journal of Chinese Language and Literature ll, no 53 (juin 2009) : 219–39. http://dx.doi.org/10.15792/clsyn..53.200906.219.
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Jiang, Qian, Wenju Lu, Kai Yang, Cyrus Hadadi, Xin Fu, Yuqin Chen, Xin Yun et al. « Sodium tanshinone IIA sulfonate inhibits hypoxia-induced enhancement of SOCE in pulmonary arterial smooth muscle cells via the PKG-PPAR-γ signaling axis ». American Journal of Physiology-Cell Physiology 311, no 1 (1 juillet 2016) : C136—C149. http://dx.doi.org/10.1152/ajpcell.00252.2015.
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Our laboratory previously showed that sodium tanshinone IIA sulfonate (STS) inhibited store-operated Ca2+ entry (SOCE) through store-operated Ca2+ channels (SOCC) via downregulating the expression of transient receptor potential canonical proteins (TRPC), which contribute to the formation of SOCC (Wang J, Jiang Q, Wan L, Yang K, Zhang Y, Chen Y, Wang E, Lai N, Zhao L, Jiang H, Sun Y, Zhong N, Ran P, Lu W. Am J Respir Cell Mol Biol 48: 125–134, 2013). The detailed molecular mechanisms by which STS inhibits SOCE and downregulates TRPC, however, remain largely unknown. We have previously shown that, under hypoxic conditions, inhibition of protein kinase G (PKG) and peroxisome proliferator-activated receptor-γ (PPAR-γ) signaling axis results in the upregulation of TRPC (Wang J, Yang K, Xu L, Zhang Y, Lai N, Jiang H, Zhang Y, Zhong N, Ran P, Lu W. Am J Respir Cell Mol Biol 49: 231–240, 2013). This suggests that strategies targeting the restoration of this signaling pathway may be an effective treatment strategy for pulmonary hypertension. In this study, our results demonstrated that STS treatment can effectively prevent the hypoxia-mediated inhibition of the PKG-PPAR-γ signaling axis in rat distal pulmonary arterial smooth muscle cells (PASMCs) and distal pulmonary arteries. These effects of STS treatment were blocked by pharmacological inhibition or specific small interfering RNA knockdown of either PKG or PPAR-γ. Moreover, targeted PPAR-γ agonist markedly enhanced the beneficial effects of STS. These results comprehensively suggest that STS treatment can prevent hypoxia-mediated increases in intracellular calcium homeostasis and cell proliferation, by targeting and restoring the hypoxia-inhibited PKG-PPAR-γ signaling pathway in PASMCs.
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Cronin, Stephen B. « (Invited) In Situ spectroscopy of Electrochemical and Photoelectrochemical Interfaces ». ECS Meeting Abstracts MA2022-02, no 48 (9 octobre 2022) : 1823. http://dx.doi.org/10.1149/ma2022-02481823mtgabs.
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We explore various aspects of electrochemistry and photoelectrochemistry using in situ spectroscopy of electrode (metal) and photoelectrode (semiconductor) interfaces under electrochemical working conditions. Using sum frequency generation (SFG) spectroscopy, we measure the voltage dependence of the orientation of D2O molecules at a graphene electrode surface, which enables us to extract the free energy orienting potential of interfacial water.1 In particular, we measure the “free OD” feature in the spectra, which corresponds to the topmost water molecule that is rotated up out of the bulk water solution and is, therefore, not hydrogen bonded. Using transient absorption spectroscopy (TAS), we measure the lifetime of hot electrons photoexcited in plasmon resonant nanostructures.5 In a similar study, we use transient reflectance spectroscopy (TRS) to measure the photoexcited carrier dynamics in a GaP/TiO2 photoelectrode, as well as the electrostatic field dynamics at this semiconductor-liquid interface in situ under various electrochemical potentials.2 Here, the electrostatic fields at the surface of the semiconductor are measured via Franz−Keldysh oscillations (FKO). These spectra reveal that the nanoscale TiO2 protection layer enhances the built-in field and charge separation performance of GaP photoelectrodes. Using surface enhanced Raman scattering (SERS) spectroscopy, we monitor local electric fields via Stark-shifts of nitrile-functionalized silicon photoelectrodes.6 By monitoring Stark shifts in graphene-enhanced Raman spectroscopy (GERS), we measure local electric fields and local charge densities at monolayer graphene electrode surfaces.3 Lastly, we measure the stacking dependence of monolayer WSe2/MoSe2 heterostructures and observe resonant excitation of interlayer excitons for photocatalytic energy conversion.4 Montenegro, A., C. Dutta, M. Mammetkuliev, H.T. Shi, B.Y. Hou, D. Bhattacharyya, B.F. Zhao, S.B. Cronin and A.V. Benderskii, Asymmetric response of interfacial water to applied electric fields. Nature, 594, 62 (2021). Xu, Z.H., B.Y. Hou, F.Y. Zhao, Z. Cai, H.T. Shi, Y.W. Liu, C.L. Hill, D.G. Musaev, M. Mecklenburg, S.B. Cronin and T.Q. Lian, Nanoscale TiO2 Protection Layer Enhances the Built-In Field and Charge Separation Performance of GaP Photoelectrodes. Nano Letters, 21, 8017-8024 (2021). Shi, H.T., B.F. Zhao, J. Ma, M.J. Bronson, Z. Cai, J.H. Chen, Y. Wang, M. Cronin, L. Jensen and S.B. Cronin, Measuring Local Electric Fields and Local Charge Densities at Electrode Surfaces Using Graphene-Enhanced Raman Spectroscopy (GERS)-Based Stark-Shifts. ACS Applied Materials & Interfaces, 11, 36252-36258 (2019). Chen, J., C.S. Bailey, D. Cui, Y. Wang, B. Wang, H. Shi, Z. Cai, E. Pop, C. Zhou and S.B. Cronin, Stacking Independence and Resonant Interlayer Excitation of Monolayer WSe2/MoSe2 Heterostructures for Photocatalytic Energy Conversion. ACS Applied Nano Materials, DOI:10.1021/acsanm.9b01898 (2020). Yu Wang, Yi Wang, Indu Aravind, Zhi Cai, Lang Shen, Boxin Zhang, Bo Wang, Jihan Chen, Bofan Zhao, Haotian Shi, Jahan M. Dawlaty, and Stephen B. Cronin. In Situ Investigation of Ultrafast Dynamics of Hot Electron-Driven Photocatalysis in Plasmon-Resonant Grating Structures. Journal of the American Chemical Society. DOI: 10.1021/jacs.1c12069 (2022). Haotian Shi, Ryan T. Pekarek, Ran Chen, Boxin Zhang, Yu Wang, Indu Aravind, Zhi Cai, Lasse Jensen, Nathan R. Neale, and Stephen B. Cronin. Monitoring Local Electric Fields using Stark Shifts on Napthyl Nitrile-Functionalized Silicon Photoelectrodes. The Journal of Physical Chemistry C, 124, 17000-17005 (2020).
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Woodward, Owen M. « ABCG2 : the molecular mechanisms of urate secretion and gout ». American Journal of Physiology-Renal Physiology 309, no 6 (15 septembre 2015) : F485—F488. http://dx.doi.org/10.1152/ajprenal.00242.2015.
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The human propensity for high levels of serum uric acid (SUA) is a trait that has defied explanation. Is it beneficial? Is it pathogenic? Its role in the human diseases like gout and kidney stones was discovered over a century ago [Richette P, Bardin T. Lancet 375: 318–328, 2010; Rivard C, Thomas J, Lanaspa MA, Johnson RJ. Rheumatology (Oxford) 52: 421–426, 2013], but today emerging new genetic and epidemiological techniques have revived an age-old debate over whether high uric acid levels (hyperuricemia) independently increase risk for diseases like hypertension and chronic kidney disease [Feig DI. J Clin Hypertens (Greenwich) 14: 346–352, 2012; Feig DI, Madero M, Jalal DI, Sanchez-Lozada LG, Johnson RJ. J Pediatr 162: 896–902, 2013; Feig DI, Soletsky B, Johnson RJ. JAMA 300: 924–932, 2008; Wang J, Qin T, Chen J, Li Y, Wang L, Huang H, Li J. PLoS One 9: e114259, 2014; Zhu P, Liu Y, Han L, Xu G, Ran JM. PLoS One 9: e100801, 2014]. Part of the mystery of the role uric acid plays in human health stems from our lack of understanding of how humans regulate uric acid homeostasis, an understanding that could shed light on the historic role of uric acid in human adaptation and its present role in human pathogenesis. This review will highlight the recent work to identify the first important human uric acid secretory transporter, ABCG2, and the identification of a common causal ABCG2 variant, Q141K, for hyperuricemia and gout.
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Wallace, Joseph M. « Comment on “The ultrastructure of type I collagen at nanoscale : large or small D-spacing distribution?” by H.-N. Su, L.-Y. Ran, Z.-H. Chen, Q.-L. Qin, M. Shi, X.-Y. Song, X.-L. Chen, Y.-Z. Zhang and B.-B. Xie, Nanoscale, 2014, 6, 8134 ». Nanoscale 7, no 3 (2015) : 1233–34. http://dx.doi.org/10.1039/c4nr03160a.
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Scott, Nina, Myra Ruka et Amy R. Jones. « Abstract 5278 : Cancer WHIRI research : Improving the early cancer pathway for indigenous NZ peoples ». Cancer Research 82, no 12_Supplement (15 juin 2022) : 5278. http://dx.doi.org/10.1158/1538-7445.am2022-5278.
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Abstract Background: Māori, Indigenous peoples of New Zealand (NZ) are twice as likely to die after a diagnosis of cancer compared to non-Māori. Cancer pathways are not designed for Māori health gain and are not pandemic resilient. Māori receive delayed poorer quality treatment and those with comorbidities are undertreated [1]. Existing inequities from time of referral to cancer services through to treatment were exacerbated by the COVID-19 response in Aotearoa NZ. Coordination of care is crucial for Māori patients and whānau (family), but poorly developed along this early part of the cancer pathway. In addition, care quality is not well monitored, and the current pathway is vulnerable to changes created by pandemic conditions. Aims: This study seeks to co-design, implement and evaluate a holistic cultural and clinical cancer service that is patient and whānau centred; the Whānau Hauora Integrated Response Initiative (WHIRI) programme. This comprehensive, pandemic resilient, racism-free, hauora (wellbeing) enhancing and responsive model of care will be designed for the early part of the secondary care cancer pathway. Design and Method: The WHIRI programme includes navigation, a holistic whānau/family hauora assessment tool, proactive management by a team of clinicians and a team responsible for making systems changes. WHIRI was launched mid-pandemic (early 2020) for kaumātua (elderly Māori) with long-term conditions and ran for 3 months. During COVID we found that WHIRI had the potential to change hospital systems and improve experiences for patients and whānau. WHIRI ensures the provision of best-practice timely treatment for Māori patients and could make large gains in closing the survival gap between Māori and non-Māori in the short- to medium-term, leading to reductions in Māori cancer deaths. We plan to redesign WHIRI into a cancer programme that functions effectively in all COVID levels using qualitative Kaupapa Māori methodology. Key to this methodology is partnerships with patients, whānau, cancer clinicians, Māori navigators and The Cancer Control Agency New Zealand. We will present our methods and co-design model of cancer care. We will outline the potential to expand the model nationally with reach from primary care all the way through to palliative care. It will also provide a platform for future research to measure the impact of WHIRI on cancer and whānau care. 1. Hill S, Sarfati D, Blakely T, Robson B, Purdie G, Chen J, et al. Survival disparities in Indigenous and non-Indigenous New Zealanders with colon cancer: the role of patient comorbidity, treatment and health service Citation Format: Nina Scott, Myra Ruka, Amy R. Jones. Cancer WHIRI research: Improving the early cancer pathway for indigenous NZ peoples [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5278.
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Ran, Jingyu, Lihua Xiao, Wei Wang, Shaoyi Jia et Jihua Zhang. « Correction : ZIF-8@polyoxometalate derived Si-doped ZnWO4@ZnO nanocapsules with open-shaped structures for efficient visible light photocatalysis ». Chemical Communications 54, no 98 (2018) : 13869. http://dx.doi.org/10.1039/c8cc90513d.
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Correction for ‘ZIF-8@polyoxometalate derived Si-doped ZnWO4@ZnO nanocapsules with open-shaped structures for efficient visible light photocatalysis’ by Jingyu Ran et al., Chem. Commun., 2018, DOI: 10.1039/c8cc06077k.
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Ta, Lisa H., Janai R. Carr-Ascher, Weixian Deng, Brandon L. Tsai, Wendy Tran, Donny Gun, Donghui Cheng et al. « Abstract 2438 : Determining the role of non-mutated C-Raf kinase in metastatic disease ». Cancer Research 82, no 12_Supplement (15 juin 2022) : 2438. http://dx.doi.org/10.1158/1538-7445.am2022-2438.
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Abstract Many aggressive epithelial cancers do not carry targetable driver mutations (Mendiratta et al. 2021, NCI-MATCH Clinical trial NCT02465060). Commonly altered signaling pathways highlight the propensity for tumors to depend on such pathways for growth and survival where genomic alterations may not be required for pathway activation. The Raf family kinases are crucial mediators of the Ras/Raf/MEK/ERK (MAPK) cascade, which has been shown to be upregulated in a subset of metastatic cancers and are mutated in many epithelial cancers. A recent study suggests non-mutated C-Raf can drive metastasis to the lungs, bone, and various other tissues (Faltermeir et al. 2016). Though the mechanism of C-Raf driven metastasis is likely through MAPK activation, C-Raf has been demonstrated to possess MAPK independent roles that may also contribute to this phenotype. In this study, we explored various C-Raf functions as drivers of metastasis in an intracardiac mouse model system. Using a series of Raf knock-out cell lines and mutants targeting functional residues in C-Raf, we demonstrated that C-Raf dimerization is necessary to drive metastasis. We further showed that the metastasis-promoting activity of C-Raf is dependent on co-expression of its family member, B-Raf, for an accelerated metastatic phenotype. However, overexpression of a kinase-dead C-Raf mutant was still able to produce metastases albeit with lower efficiency, suggesting C-Raf possesses non-kinase dependent functions that also contributed to metastasis. Together, these results point to the importance of Raf non-canonical roles in oncogenic processes that may be unappreciated in metastatic disease. Citation Format: Lisa H. Ta, Janai R. Carr-Ascher, Weixian Deng, Brandon L. Tsai, Wendy Tran, Donny Gun, Donghui Cheng, Jihui Sha, Yeonjoo Hwang, John W. Phillips, Matthew B. Obusan, Nathanael J. Bangayan, Miyako Noguchi, Zhiyuan Mao, Chia-Chun Chen, Liang Wang, Grigor Varuzhanyan, John D. Gordon, James W. Wohlschlegel, Owen N. Witte. Determining the role of non-mutated C-Raf kinase in metastatic disease [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 2438.
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Kim, Kyoung-Ran, Taemin Lee, Byeong-Su Kim et Dae-Ro Ahn. « Correction : Utilizing the bioorthogonal base-pairing system of l-DNA to design ideal DNA nanocarriers for enhanced delivery of nucleic acid cargos ». Chemical Science 6, no 3 (2015) : 2122. http://dx.doi.org/10.1039/c5sc90009c.
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Correction for ‘Utilizing the bioorthogonal base-pairing system of l-DNA to design ideal DNA nanocarriers for enhanced delivery of nucleic acid cargos’ by Kyoung-Ran Kim et al., Chem. Sci., 2014, 5, 1533–1537.
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Pan, Julie Y., William E. Fieles, Anne M. White, Mark M. Egerton et David S. Silberstein. « Ges, a Human Gtpase of the Rad/Gem/Kir Family, Promotes Endothelial Cell Sprouting and Cytoskeleton Reorganization ». Journal of Cell Biology 149, no 5 (29 mai 2000) : 1107–16. http://dx.doi.org/10.1083/jcb.149.5.1107.
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Rad, Gem/Kir, and mRem (RGK) represent a unique GTPase family with largely unknown functions (Reynet, C., and C.R. Kahn. 1993. Science. 262:1441–1444; Cohen, L., R. Mohr, Y. Chen, M. Huang, R. Kato, D. Dorin, F. Tamanoi, A. Goga, D. Afar, N. Rosenberg, and O. Witte. Proc. Natl. Acad. Sci. USA. 1994. 91:12448–12452; Maguire, J., T. Santoro, P. Jensen, U. Siebenlist, J. Yewdell, and K. Kelly. 1994. Science. 265:241–244; Finlin, B.S., and D.A. Andres. 1997. J. Biol. Chem. 272:21982–21988). We report that Ges (GTPase regulating endothelial cell sprouting), a human RGK protein expressed in the endothelium, functions as a potent morphogenic switch in endothelial cells (ECs). Ges function is sufficient to substitute for angiogenic growth factor/extracellular matrix (ECM) signals in promoting EC sprouting, since overexpression of Ges in ECs cultured on glass leads to the development of long cytoplasmic extensions and reorganization of the actin cytoskeleton. Ges function is also necessary for Matrigel-induced EC sprouting, since this event is blocked by its dominant negative mutant, GesT94N, predicted to prevent the activation of endogenous Ges through sequestration of its guanine nucleotide exchange factor. Thus, Ges appears to be a key transducer linking extracellular signals to cytoskeleton/morphology changes in ECs.
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Sauvigny, Friedrich. « Die zweite Variation von Minimalfl�chen im ? p mit polygonalem Rand ». Mathematische Zeitschrift 189, no 2 (juin 1985) : 167–84. http://dx.doi.org/10.1007/bf01175042.
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Teoh, Karen M. « Lessons from my School : The Journey of the French Nuns and their Convent Schools by Chen Yen Ling ». Journal of the Malaysian Branch of the Royal Asiatic Society 93, no 2 (2020) : 248–50. http://dx.doi.org/10.1353/ras.2020.0040.
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Teoh, Karen M. « Lessons from my School : The Journey of the French Nuns and their Convent Schools by Chen Yen Ling ». Journal of the Malaysian Branch of the Royal Asiatic Society 93, no 2 (2020) : 248–50. http://dx.doi.org/10.1353/ras.2020.0040.
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Vinken, G. C. M., K. F. Boersma, D. J. Jacob et E. W. Meijer. « Accounting for non-linear chemistry of ship plumes in the GEOS-Chem global chemistry transport model ». Atmospheric Chemistry and Physics Discussions 11, no 6 (23 juin 2011) : 17789–823. http://dx.doi.org/10.5194/acpd-11-17789-2011.
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Abstract. We present a computationally efficient approach to account for the non-linear chemistry occurring during the dispersion of ship exhaust plumes in a global 3-D model of atmospheric chemistry (GEOS-Chem). We use a plume-in-grid formulation where ship emissions age chemically for 5 h before being released in the global model grid. Besides reducing the original ship NOx emissions in GEOS-Chem, our approach also releases the secondary compounds ozone and HNO3, produced in the 5 h after the original emissions, into the model. We applied our improved method and also the widely used "instant dilution" approach to a 1-yr GEOS-Chem simulation of global tropospheric ozone-NOx-VOC-aerosol chemistry. We also ran simulations with the standard model, and a model without any ship emissions at all. Our improved GEOS-Chem model simulates up to 0.1 ppbv (or 90 %) more NOx over the North Atlantic in July than GEOS-Chem versions without any ship NOx emissions at all. "Instant dilution" overestimates NOx concentrations by 50 % (0.1 ppbv) and ozone by 10–25 % (3–5 ppbv) over this region. These conclusions are supported by comparing simulated and observed NOx and ozone concentrations in the lower troposphere over the Pacific Ocean. The comparisons show that the improved GEOS-Chem model simulates NOx concentrations in between the instant diluting model and the model with no ship emissions, and results in lower O3 concentrations than the instant diluting model. The relative differences in simulated NOx and ozone between our improved approach and instant dilution are smallest over strongly polluted seas (e.g. North Sea), suggesting that accounting for in-plume chemistry is most relevant for pristine marine areas.
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Richard, Guillaume. « L��chec du projet Bufnoir de regroupement des sciences d��tat ». Revue d'anthropologie des connaissances 13,N�1, no 1 (2019) : 91. http://dx.doi.org/10.3917/rac.042.0091.
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Turyanti, Ana, et C. Chaerunnisa. « The Estimation of Rainwater Acidity Level based on the Ambient Air Pollutants Concentration (Case Study : DKI Jakarta) ». Agromet 31, no 2 (13 décembre 2017) : 71. http://dx.doi.org/10.29244/j.agromet.31.2.71-79.
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Nowadays, acid rain is a common phenomenon occurring in metropolitan city, such as Jakarta. Human activities including transportation and industries in and surrounding this city have increased pollutants in the atmosphere, which lead to an increased of acid rain events. Analyzing on rainwater pH is common approach to assess whether an acid rain occurs or not. However, information on this pH value for greater Jakarta is limited. Here we used a combined of Henry's law approach and Weather Research Forecasting-Chemistry (WRF-Chem) to estimate rainwater pH in Jakarta. The WRF-Chem was employed to generate SO<sub>2</sub> and NO<sub>2</sub> concentrations. Results showed that rainwater pH is below the threshold (pH = 5.6) in observation and modeling (Henry’s approach) throughout greater Jakarta. Rainwater pH showed a diurnal fluctuation with low value during night and morning, but high value at afternoon. Likely, season contributed to distribution of acid rain. Based on Henry’s approach, some regions (Bundaran HI, Kebon Jeruk, and Jagakarsa) revealed a high potency of acid rain for rainy season as indicated by the H<sup>+</sup> concentration. On other hand, a high potency of acid rain during dry season was observed in Kelapa Gading and Bundaran HI. Our findings indicated that traffic may influence on rain acid events as shown by a high H<sup>+</sup> concentration in Bundaran HI both dry and wet seasons.
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Guo, Chunwei, Hui Xiao, Huiling Yang et Wei Wen. « Effects of Anthropogenic Aerosols on a Heavy Rainstorm in Beijing ». Atmosphere 10, no 4 (27 mars 2019) : 162. http://dx.doi.org/10.3390/atmos10040162.
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A heavy rainstorm occurred in Beijing on 19–20 July 2016. The Weather Research and Forecasting Model coupled with Chemistry (WRF-Chem) was used to investigate the effects of anthropogenic aerosols on precipitation and microphysical processes. Three conditions were simulated by altering the anthropogenic emissions. When the anthropogenic emissions were increased by 10 times, the area-average accumulated rainfall amount and maximum accumulated rainfall amount both decreased. The cloud water mixing ratio increased and the rain mixing ratio decreased. The radii of cloud droplets decreased, and the collision efficiency of cloud water by rain and the autoconversion rate of cloud water into rain were both low. When the anthropogenic emission was 10% of the original emission, the area of accumulated rainfall amounts greater than 25 mm in the Beijing area was 10% larger than those of the other two tests. The collision efficiency and autoconversion rate of cloud water into rain were high for large contact areas and large cloud droplets. The graupel mixing ratio was the largest. Thus, the process of melting of graupel into rain was the largest. In the WRF-Chem model, the aerosols did not participate as ice nuclei (IN) in the ice-phase microphysical processes, and therefore the aerosols could influence only the warm rain processes and mix-phased processes near the freezing level line. For no influence on ice-phase microphysical processes, the snow and ice mixing ratios did not show many differences among the different tests.
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Zakharov, Anton O. « Special Relationship in the Malay World : Indonesia and Malaysia by Ho Ying Chan ». Journal of the Malaysian Branch of the Royal Asiatic Society 92, no 1 (2019) : 120–24. http://dx.doi.org/10.1353/ras.2019.0011.
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Ning, Li, Ji-Shen Wang et Bao-Zhen Hua. « Morphological phylogenetic analyses and taxonomic revision of the Panorpa davidi group (Mecoptera : Panorpidae) ». Arthropod Systematics & ; Phylogeny 79 (15 juillet 2021) : 309–42. http://dx.doi.org/10.3897/asp.79.e65179.
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Abstract The Chinese Panorpa species without anal horn are normally assigned to the Panorpa davidi group. Here, we taxonomically revise the P. davidi group, which currently includes 17 known species and four new species: P. gaokaii sp. nov., P. huayuani sp. nov., P. uncinata sp. nov. and P. yaoluopingensis sp. nov. Panorpa shanyangensis Chou & Wang, 1981 and P. sexspinosa zhongnanensis Chou & Ran, 1981 are treated as junior synonyms of P. sexspinosa Cheng, 1949. We describe for the first time the male of P. stigmosa Zhou, 2006, and the females of P. curva Carpenter, 1938, P. davidi Navás, 1908, P. difficilis Carpenter, 1938, P. fructa Cheng, 1949, and P. jinchuana Hua, Sun & Li, 2001. A key to species of the group is provided. Phylogenetic analyses of maximum parsimony and maximum likelihood based on 79 morphological characters show that the newly defined P. davidi group is a well-supported monophyletic group and is sister to the genus Cerapanorpa Gao, Ma & Hua, 2016.
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Ning, Li, Ji-Shen Wang et Bao-Zhen Hua. « Morphological phylogenetic analyses and taxonomic revision of the Panorpa davidi group (Mecoptera : Panorpidae) ». Arthropod Systematics & ; Phylogeny 79 (15 juillet 2021) : 309–42. http://dx.doi.org/10.3897/asp.79.e64325.
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Abstract The Chinese Panorpa species without anal horn are normally assigned to the Panorpa davidi group. Here, we taxonomically revise the P. davidi group, which currently includes 17 known species and four new species: P. gaokaii sp. nov., P. huayuani sp. nov., P. uncinata sp. nov. and P. yaoluopingensis sp. nov. Panorpa shanyangensis Chou & Wang, 1981 and P. sexspinosa zhongnanensis Chou & Ran, 1981 are treated as junior synonyms of P. sexspinosa Cheng, 1949. We describe for the first time the male of P. stigmosa Zhou, 2006, and the females of P. curva Carpenter, 1938, P. davidi Navás, 1908, P. difficilis Carpenter, 1938, P. fructa Cheng, 1949, and P. jinchuana Hua, Sun & Li, 2001. A key to species of the group is provided. Phylogenetic analyses of maximum parsimony and maximum likelihood based on 79 morphological characters show that the newly defined P. davidi group is a well-supported monophyletic group and is sister to the genus Cerapanorpa Gao, Ma & Hua, 2016.
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Vinken, G. C. M., K. F. Boersma, D. J. Jacob et E. W. Meijer. « Accounting for non-linear chemistry of ship plumes in the GEOS-Chem global chemistry transport model ». Atmospheric Chemistry and Physics 11, no 22 (23 novembre 2011) : 11707–22. http://dx.doi.org/10.5194/acp-11-11707-2011.
Texte intégralRésumé :
Abstract. We present a computationally efficient approach to account for the non-linear chemistry occurring during the dispersion of ship exhaust plumes in a global 3-D model of atmospheric chemistry (GEOS-Chem). We use a plume-in-grid formulation where ship emissions age chemically for 5 h before being released in the global model grid. Besides reducing the original ship NOx emissions in GEOS-Chem, our approach also releases the secondary compounds ozone and HNO3, produced during the 5 h after the original emissions, into the model. We applied our improved method and also the widely used "instant dilution" approach to a 1-yr GEOS-Chem simulation of global tropospheric ozone-NOx-VOC-aerosol chemistry. We also ran simulations with the standard model (emitting 10 molecules O3 and 1 molecule HNO3 per ship NOx molecule), and a model without any ship emissions at all. The model without any ship emissions simulates up to 0.1 ppbv (or 50%) lower NOx concentrations over the North Atlantic in July than our improved GEOS-Chem model. "Instant dilution" overestimates NOx concentrations by 0.1 ppbv (50%) and ozone by 3–5 ppbv (10–25%), compared to our improved model over this region. These conclusions are supported by comparing simulated and observed NOx and ozone concentrations in the lower troposphere over the Pacific Ocean. The comparisons show that the improved GEOS-Chem model simulates NOx concentrations in between the instant dilution model and the model without ship emissions, which results in lower O3 concentrations than the instant dilution model. The relative differences in simulated NOx and ozone between our improved approach and instant dilution are smallest over strongly polluted seas (e.g. North Sea), suggesting that accounting for in-plume chemistry is most relevant for pristine marine areas.
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Kwok, John. « Aristocracy of Armed Talent : The Military Elite in Singapore by Samuel Ling Wei Chan ». Journal of the Malaysian Branch of the Royal Asiatic Society 93, no 2 (2020) : 233–35. http://dx.doi.org/10.1353/ras.2020.0039.
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Kwok, John. « Aristocracy of Armed Talent : The Military Elite in Singapore by Samuel Ling Wei Chan ». Journal of the Malaysian Branch of the Royal Asiatic Society 93, no 2 (2020) : 233–35. http://dx.doi.org/10.1353/ras.2020.0039.
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He, J. P., R. Kram et T. A. McMahon. « Mechanics of running under simulated low gravity ». Journal of Applied Physiology 71, no 3 (1 septembre 1991) : 863–70. http://dx.doi.org/10.1152/jappl.1991.71.3.863.
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Using a linear mass-spring model of the body and leg (T. A. McMahon and G. C. Cheng. J. Biomech. 23: 65–78, 1990), we present experimental observations of human running under simulated low gravity and an analysis of these experiments. The purpose of the study was to investigate how the spring properties of the leg are adjusted to different levels of gravity. We hypothesized that leg spring stiffness would not change under simulated low-gravity conditions. To simulate low gravity, a nearly constant vertical force was applied to human subjects via a bicycle seat. The force was obtained by stretching long steel springs via a hand-operated winch. Subjects ran on a motorized treadmill that had been modified to include a force platform under the tread. Four subjects ran at one speed (3.0 m/s) under conditions of normal gravity and six simulated fractions of normal gravity from 0.2 to 0.7 G. For comparison, subjects also ran under normal gravity at five speeds from 2.0 to 6.0 m/s. Two basic principles emerged from all comparisons: both the stiffness of the leg, considered as a linear spring, and the vertical excursion of the center of mass during the flight phase did not change with forward speed or gravity. With these results as inputs, the mathematical model is able to account correctly for many of the changes in dynamic parameters that do take place, including the increasing vertical stiffness with speed at normal gravity and the decreasing peak force observed under conditions simulating low gravity.
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Khoon, Chan Chee. « The Private Healthcare Sector in Johor : Trends and Prospects by Meghann Ormond, Lim Chee Han ». Journal of the Malaysian Branch of the Royal Asiatic Society 91, no 2 (2018) : 173–76. http://dx.doi.org/10.1353/ras.2018.0028.
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Cheng, Zhe, Fei Chen, Xile Liu, Cong Gao, Linchao Jia et Yuanzhi Lao. « Abstract 5460 : Preclinical characterization of QLH11906, a novel pan-RAF inhibitor ». Cancer Research 82, no 12_Supplement (15 juin 2022) : 5460. http://dx.doi.org/10.1158/1538-7445.am2022-5460.
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Abstract Background: The type 1/2 BRAF inhibitors (e.g., vemurafenib) have been used for patients with BRAFV600E-mutant tumors. But the application of the inhibitors was restricted to a few types of tumors (e.g., melanoma). Common adverse effects such as pruritus and skin papilloma have limited the usage. It could be attributed to the paradoxical activation of the MAPK pathway. The paradoxical activation also leads to tumor promotion in BRAF wild-type melanoma and skin toxicity in 30%-70% patients with KRAS mutations. Therefore, development of type II pan-RAF inhibitors which avoid MAPK paradoxical activation is necessary. Methods: The selective pan-RAF inhibitor QLH11906 was tested on A/B/C RAF kinases and a representative kinase panel. Both 2D and 3D proliferation studies were conducted for cell lines with BRAF and various KRAS mutations, followed by both immunoprecipitation and ERK phosphorylation assays to elucidate the mode of action. Combination studies with MEK inhibitors were implemented in both KRAS-mutant cell lines and BRAF/KRAS-mutant patient derived organoids (PDO). Single-agent and combination studies were also carried out in vivo on both BRAF/KRAS-mutant cell line-derived xenograft (CDX) and KRAS-mutant patient-derived xenograft (PDX) models. Results: QLH11906 inhibited wild-type A/B/C RAF and BRAFV600E with the IC50 of 4.9, 1.9, 0.5, and 1.1 nM, respectively, and showed no inhibition at 1 μM in a selectivity panel of 28 kinases except for DDR1 and DDR2. Under 2D culture condition, QLH11906 inhibited proliferation of various BRAF/KRAS-mutant cell lines (IC50 300-1700 nM) and suppressed ERK phosphorylation (IC50 20-600 nM). In 3D cultures, QLH11906 showed higher activity in proliferation suppression in both HCT116 (KRASG13D, IC50 24 nM 3D vs 1186 nM 2D) and Calu-6 (KRASQ61K, IC50 85 nM 3D vs 1411 nM 2D). In immunoprecipitation studies with HCT116 and Calu-6 cells, both BRAF homodimers and BRAF/CRAF heterodimers could be detected under the treatment of QLH11906. QLH11906 showed synergistic effect when combined with MEK inhibitors trametinib or cobimetinib in KRAS-mutant cell lines, including A549 (KRASG12S), Calu-6, HCT116, NCIH2122 (KRASG12C) and Panc1005 (KRASG12D), and 77%-99% tumor suppression was reached at the expected clinical Ctrough concentrations. Synergistic effects with trametinib were observed in PDO models including pancreatic cancers (KRASG12D and KRASG12V), colon cancers (KRASG12D and KRASG13D) and lung cancers (KRASG12V). QLH11906 also promoted tumor shrinkage in vivo as a single agent in Calu-6, HCT116, and Colo-205 (BRAFV600E) CDX models or combined with trametinib in PDX models (KRASG12C lung cancers and KRASG12C colon cancers) Conclusion: QLH11906 is a highly selective pan-RAF inhibitor with promising antitumor activity both in vitro and in vivo. It is hopeful to be a therapeutic agent for BRAF and KRAS-mutant tumor patients. Citation Format: Zhe Cheng, Fei Chen, Xile Liu, Cong Gao, Linchao Jia, Yuanzhi Lao. Preclinical characterization of QLH11906, a novel pan-RAF inhibitor [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5460.
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Singhal, Rahul, Kushagr Singhal, Rudra Patel, Peter Lemaire, Sreekanth Ponnada et Rakesh Sharma. « Electrochemical Characterizations of Ternary MnO2/Cus/Rgo Materials for Supercapacitor Applications ». ECS Meeting Abstracts MA2022-02, no 1 (9 octobre 2022) : 72. http://dx.doi.org/10.1149/ma2022-02172mtgabs.
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Supercapacitors are considered as a new class of energy storage device because of their high power density, environmentally friendliness, long cycleability, and flexible design capabilities. MnO2 and CuS have been found to be promising for supercapacitor applications because of their low cost, abundance in nature, and are environmentally friendly. Besides this, reduced graphene oxide emerged as most promising carbon materials for energy storage applications because of its high specific surface area, good electrical conductivity, and ability to attach metal oxide without any agglomeration. Recently, it has been reported that ternary nanocomposites have superior electrochemical performances because of their synergistic effect, which help to enhance the charge movement within the electrode material. We already reported that the specific capacitance of CuS and MnO2 as 158 F/g and 300 F/g at current densities of 0.5 A/g, respectively [1,2]. In this work we have synthesized MnO2/CuS/rGO ternary nanocomposite by hydrothermal method. The physical characterization of the synthesized materials was carried out using X-Ray diffraction, scanning electron microscopy, differential scanning calorimetry(DSC), and thermogravimetric analysis (TGA). All electrochemical measurements were conducted in standard three-electrode configuration, using a platinum wire, Ag/AgCl, and MnO2/CuS/rGO as a counter, reference, and working electrode, respectively. The results related to physical characterization, specific capacitance, cycleability, and energy density will be presented. Reference: Rahul Singhal, David Thorne, Peter K. LeMaire, Xavier Martinez, Chen Zhao, Ram K. Gupta, David Uhl, Ellen Scanley, Christine C. Broadbridgeand Rakesh K. Sharma, AIP Advances 10, (2020) 035307; https://doi.org/10.1063/1.5132713. Rahul Singhal, Justin Fagnoni, David Thorne, Peter K. LeMaire, Xavier Martinez, Chen Zhao, Ram K. Gupta, David Uhl, Ellen Scanley, Christine C. Broadbridge, Mani Manivannan, MRS Advances, 4 (13) 777-782 (2019), https://doi.org/10.1557/adv.2019.86
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Музраева, Деляш Николаевна, Антонина Саар-ооловна Донгак et Ольга Александровна Максимова. « Тексты Праджняпарамиты в коллекции тувинского института ». New Research of Tuva, no 4 (30 novembre 2022) : 127–36. http://dx.doi.org/10.25178/nit.2022.4.10.
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В статье дается описание буддийских текстов из разряда литературы Праджняпарамиты, которые хранятся в Научном архиве Тувинского института гуманитарных и прикладных социально-экономических исследований при Правительстве Республики Тыва.
Вводятся в научный оборот описания рукописей и ксилографических изданий таких сочинений, как «Алмазная сутра» или «Ваджраччхедика» (тиб. ’phags pa shes rab kyi pha rol tu phyin pa rdo rje gcod pa zhes bya ba theg pa chen po’i mdo), «Сутра сердца бхагавати праджняпарамита хридая» (тиб. bcom ldan ’das ma shes rab kyi pha rol tu phyin pa’i snying po bzhugs so), «Праджняпарамита в 8000 строф (шлок)» (тиб. ’phags pa shes rab kyi pha rol tu phyin pa brgyad stong pa bzhugs so) и др. Важность данных сутр в традиции махаяны неизменна и на сегодняшний день. Об этом свидетельствуют комментарии как высоких традиционных учителей буддизма, так и ученых-буддологов нашего времени.
Среди текстов описываемой коллекции встретились также сокращенные версии, относящиеся к т. н. «сакральным формулам», краткие извлечения из текстов в составе сборников и подборок. Суть учения о запредельной мудрости праджняпарамиты (тиб. shes rab kyi pha rol tu phyin pa) — познание пустотности явлений — представляет интерес как для практиков традиции, так и для ученых-философов, антропологов, культурологов и специалистов др. дисциплин.
Рассмотренные источники занимают важное место в истории распространения буддизма в регионах России (Тува, Бурятия, Калмыкия) и Монголии. Тексты праджняпарамиты являлись обязательным атрибутом буддийских храмов.
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BENAICHETA, Nora, Fatima Zohra LABBACI, Malika BOUCHENAK et Farida Ouda BOUKORTT. « Sardine proteins mitigate hyperglycemia and oxidative stress in type 2 diabetic rat ». Nutrition & ; Santé 94, no 01 (30 juin 2015) : 6–15. http://dx.doi.org/10.30952/ns.4.1.3.
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TABANI, Khadidja. « Hypolipidemic effect of colocynth alkaloids in Wistar rat fed high-fat diet ». Nutrition & ; Santé 04, no 02 (31 décembre 2015) : 84–89. http://dx.doi.org/10.30952/ns.4.2.7.
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M, Sabarinathan, Ananthi N et Ashwin Raj H. « Comparative study of various methods in the estimation of blood HbA1c and its outcome ». International Journal of Research in Pharmaceutical Sciences 11, SPL2 (8 avril 2020) : 43–47. http://dx.doi.org/10.26452/ijrps.v11ispl2.2063.
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Diabetes mellitus is a major health problem all over the world. Blood glucose measurement has limited value in assessing the long term glycaemic control. Estimation of HbA1c is now routinely used in clinical laboratories for long term assessment of glyceamic control. The result of different methods of HbA1C estimation has a lot of variations and hence it is essential to compare their results. This study is aimed to assess the accuracy and reliability of estimation of HbA1c levels by PEITT and Column Chromatography with ion-exchange resin by comparing it with the hba1c levels of High-performance liquid chromatography (HPLC) which is a reference method. We have included 50 patients of type 2 diabetes mellitus in our study. HbA1c was determined using BIO RAD D-10 HbA1c Analyzer, Immuno-turbidimetric assay in ERBA-Chem semi automated analyzer and Column chromatography with Ion-exchange resin method in ERBA-Chem semi automated analyzer. The results obtained from Immuno-turbidimetric assay and Ion-exchange resin methods were compared with the results of BIO RAD D-10 HbA1c Analyzer. The results obtained from Particle Enhanced Immuno-Turbidimetric Test method showed a better correlation with BIO RAD D-10 HbA1c Analyzer than Column chromatography with Ion-exchange resin (CCG-IER). Hence, Particle Enhanced Immuno-Turbidimetric Test method is more reliable and accurate and can be used as an alternative method to HPLC in clinical laboratories.
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배원정. « Chung Chan-young, Modern Female Painter, the Color Painting on Flowers and Birds ». Korean Bulletin of Art History ll, no 53 (décembre 2019) : 7–33. http://dx.doi.org/10.15819/rah.2019..53.7.
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HARRAT, Nour El-Imene, Zoubida Imene TAIR,, Sabrine LOUALA, Nabila BOUKHARI,, Faiza DEHIBA et Myriem LAMRI-SENHADJI. « Argan oil supplementation reduces hyperglycemia, dyslipidemia and oxidant stress in obese rats ». Nutrition & ; Santé 94, no 01 (30 juin 2015) : 16–26. http://dx.doi.org/10.30952/ns.4.1.4.
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Jiang, Lu, et Bao-Zhen Hua. « Morphological comparison of the larvae of Panorpa obtusa Cheng and Neopanorpa lui Chou & ; Ran (Mecoptera : Panorpidae) ». Zoologischer Anzeiger - A Journal of Comparative Zoology 255 (mars 2015) : 62–70. http://dx.doi.org/10.1016/j.jcz.2015.02.004.
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Dusi, S., M. Donini et F. Rossi. « Mechanisms of NADPH oxidase activation in human neutrophils : p67phox is required for the translocation of rac 1 but not of rac 2 from cytosol to the membranes ». Biochemical Journal 308, no 3 (15 juin 1995) : 991–94. http://dx.doi.org/10.1042/bj3080991.
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NADPH oxidase is the enzyme complex responsible for the production of oxygen radicals in phagocytes. On neutrophil stimulation, the cytosolic components of NADPH oxidase, p67phox and p47phox, as well as the Ras-related G-protein rac 2, are translocated from the cytosol to cell membranes where they associate with a flavocytochrome b to form a functional complex. Besides rac 2, rac 1 G-protein is also involved in the activation of the NADPH oxidase, but, to date, it has not been documented whether it is also translocated in activated neutrophils. In this paper we show that: (a) in neutrophils stimulated with formylmethionyl-leucylphenylalanine, concanavalin A or phorbol 12-myristate 13-acetate, both rac 1 and rac 2 are translocated from cytosol to the membranes; (b) in neutrophils from a patient with a form of chronic granulomatous disease in which p67phox is absent, rac 2 and p47phox were translocated as in normal neutrophils on stimulation with the above agonists, but rac 1 failed to be translocated from the cytosol to the membranes. This is the first demonstration that, in activated neutrophils, rac 1 is translocated from the cytosol to the membranes and this translocation requires p67phox. These results, coupled with those showing that rac 2 is not translocated in activated neutrophils lacking p47phox [El Benna, Ruedi and Babior (1994) J. Biol. Chem. 269, 6729-6734], may suggest that the assembly of the cytosolic components of NADPH oxidase on the plasma membrane takes place through selective coupling of activated rac 1 and rac 2 with p67phox and p47phox respectively.
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Jallais, Joël. « Mon expérience de Rédacteur en chef de Recherche et Applications en Marketing : mémoire d’un pionnier ». Recherche et Applications en Marketing (French Edition) 36, no 2 (22 mars 2021) : 96–99. http://dx.doi.org/10.1177/0767370120972265.
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Mon expérience comme Rédacteur en chef de la revue RAM est celle d’un pionnier avec des enjeux et contraintes spécifiques des années 1987–1990, dans l’édition scientifique : 1) alimenter en articles de recherche de qualité une toute nouvelle revue francophone auprès d’une communauté d’enseignants universitaires, pas encore rompue à cette activité ; 2) relever le défi de faire fonctionner selon des standards internationaux une revue reposant sur seul bénévolat, dans le contexte technique de cette époque.
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Dody, Firman, et Edward Danakusumah. « Rekayasa Rematurasi Ikan Koki Oranda (Carassius sp.) Menggunakan Hormon Oodev Pada Dosis Yang Berbeda ». Jurnal Ilmiah Satya Minabahari 3, no 1 (31 août 2017) : 44–51. http://dx.doi.org/10.53676/jism.v3i1.41.
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Oranda chef fish is a type of goldfish that has a round body with a small head and a broad tail. This fish comes from mainland china, but in Indonesia has long been able to be cultivated. The prospect of maintaining ori chef fish is quite promising because for marketing in addition to the target in the country is also a type of fish in the export and the price is quite high. Oranda Chef Fish has some favorable properties to be cultivated for example the relatively high price of spawning cycle is relatively shorter. The purpose of the other researchers Knowing how to accelerate the maturity of the gonad chef oranda using hormones Oodev with different doses. Know the effect of Oodev hormone on remediation of ori chef fish. Know the dosage of OODev hormone effective for remandasi fish chef oranda This study used an experimental method with Completely Randomized Design (RAL) consisting of 4 treatments in which the first treatment of prospective parent who was not given Oodev hormone or as control, treatment of the two candidate mothers given a dose of 0.5 mL / kg hormone, treatment of the three prospective mothers With a dose of 1 mL / kg and the last treatment where the prospective parent with a dose of 1.5 mL / kg. Each treatment was repeated 3 times each. With 8 test parameters namely; Index gonad maturity, histology gonad, fekuenditas, egg diameter, degree of egg fertilization, degree of egg penetration, larval larva and water quality. And using ANOVA Statistic Analysis data analysis tool. Based on the results of the research of all parameters Test that the dose of 1 mL / kg is the dominant dose and most effective for maturity of the parent candidate gonad and larval life rate.
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Ford, Renée. « Devotion, a Lamp That Illuminates the Ground : Non-Referential Devotional Affect in Great Completeness ». Religions 11, no 3 (23 mars 2020) : 148. http://dx.doi.org/10.3390/rel11030148.
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I explore how devotion (mos gus) is re-interpreted as non-dual and non-conceptual through Mahāyoga tantric creation (skyed) and completion (rdzogs) stage practices as an expression of the ground (bzhi) for Longchenpa (klong chen rab ‘byams, 1308–1364) and Jigme Lingpa (‘jigs med gling pa, 1730–1785). Devotion, a felt-sense, allows for there to be something akin to a residue from these mental constructs that allows for a practitioner to carry over her experience into a later phase of meditation. Firstly, devotion, as an affect is necessarily non-dual because tantra entails pure perception (dag snang). Secondly, I demonstrate that for Longchenpa, tantra is a method that relies on non-conceptual frameworks. Finally, I address how devotion pivots ordinary mind (sems) towards recognizing this ground. Through this progression, there is a profound synchronicity between full-on openness to devotion and the infinitely spacious reality.
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Swedenburg, Ted. « On the Origins of Pop Rai ». Middle East Journal of Culture and Communication 12, no 1 (29 mars 2019) : 7–34. http://dx.doi.org/10.1163/18739865-01201003.
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Abstract In this paper, I examine the emergence of pop rai in western Algeria during the 1970s and the subsequent transformation of rai into a very different sound, and a national and international phenomenon. The study is based in part on an analysis of previously hard-to-find pop rai recordings now available on the internet. Pop rai’s origins are in the rural music of the male performers of bédoui music and particularly the female cheikhat. After independence, constraints were imposed on female performances, and so, during the 1960s, male singers, most famously Belkacem Bouteldja, began to record a modern version of the cheikhat repertoire. Messaoud Bellemou, a trumpet player from the city of Aïn Témouchent, played a major role in the further development of the music; he created an ensemble that included singers like Boutaïba Sghir, Belkacem Bouteldja, Hamani Hadjoum and Younes Benfissa, that modernized the instrumental backing and overall sound of western Algeria’s local folkloric music, and thereby created the genre known as pop rai. Other artists who played a role in the development of pop rai include the Oran-based Chaba Fadela, who started her career with Bellemou’s group, Cheb Khaled, and Groupe El Azhar; and from Sidi Bel Abbès, guitarist and singer Ahmed Zergui. During the 1980s, rai music became national, and producer Rachid Baba Ahmed of Tlemcen further modernized its sound through the use of electronic keyboards. By the late 1980s, rai had become international, a new generation of artists had emerged, and the ensembles and artists that forged pop rai in the 1970s were displaced. Today those artists are largely forgotten, and this critical period in the history of rai remains seriously understudied.
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Xigui, Qiu. « The Early China Forum An Examination of Whether the Charges in Shang Oracle-Bone Inscriptions are Questions* ». Early China 14 (1989) : 77–114. http://dx.doi.org/10.1017/s0362502800002601.
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Oracle-bone scholars have long uniformly read the charges (i.e., the portion that mentions the event being divined) of Shang oracle-bone inscriptions as questions. Since the 1970's, many foreign oracle-bone scholars have proposed a new view that the charges are never questions, or at least are generally not questions. Whether or not the charges are actually questions is a very important question bearing not only on oracle bone studies, but also on research on ancient divination and on ancient Chinese grammar. Based on an examination of a great number of Shang oracle-bone inscriptions, the author of this essay believes that charges that can now be determined to be questions are mainly those choice-type charges in early inscriptions that contain the final particles yi and zhi, and true-or-false type charges that contain yi. Charges of the type “V bu V” (such as “rain not rain” [yu bu yu]) and “V bu,” regarded by many as choice-type questions, are actually comprised of the charge and a verification or use notation, the “bu V” being a verification and the “bu” being either a verification or a use notation (similar to the notation bu yong, “do not use”). Charges that can now be determined not to be questions are mainly in those inscriptions with complex charges, such as “this *spring the king ought not ally with Wang Cheng to attack Xia Wei, (for if he does) he will not receive divine assistance” (jin ?chun wang wu bi Wang Cheng fa Xia? Wei, fu qi shou you you, and “On ren we ought not hunt, (for if we do) it will rain” (ren wu tian, qi yu), the syntax of which shows that they cannot be questions.
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GDOURA, Nesrine, Jean-Claude MURAT, Khansa CHAABOUNI, Fatma MAKNI AYADI et Abdelfattah I. ELFEK. « Effects of Pinus Halepensis oil on hyperuricemia, lipid peroxidation, and antioxidant enzymes activities in rat ». Nutrition & ; Santé 94, no 01 (30 juin 2015) : 27–34. http://dx.doi.org/10.30952/ns.4.1.5.
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Carbone, Giuseppe, et Bojan Nemec. « Foreword for special issue for RAAD 2013 Conference – ROBOTICA ». Robotica 33, no 5 (11 mai 2015) : 1033. http://dx.doi.org/10.1017/s0263574715000296.
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This special issue is associated with the 22nd International Workshop on Robotics in the Alpe-Adria-Danube Region (RAAD2013) that took place on September 11 to 13, 2013 in Portorož, Slovenia. The RAAD conference series was established in 1992 (initially under the name RAA). At that time, RAAD played an important role towards enhancing international cooperation among neighborhood countries, while addressing the evolution of robotics from classical industrial applications to novel challenging areas such as service and humanoid robotics. Although RAAD conference got its name from a geographical region (Alpe-Adria-Danube), it was never meant to be limited to participants coming solely from this region. This aspect has grown through the years and in 2013 RAAD has got 50 papers from authors who came from 20 different countries. Invited plenary lectures have been delivered by Prof. Auke Ijspeert from EPFL (Switzerland), Prof. Alin Albu-Schäffer from DLR (Germany), and prof. I-Ming Chen from Nanyang Technological University (Singapore).
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Siek, Theodore J., Corey W. Stradling, Marc W. McCain et Timothy C. Mehary. « Computer-aided identifications of thin-layer chromatographic patterns in broad-spectrum drug screening ». Clinical Chemistry 43, no 4 (1 avril 1997) : 619–26. http://dx.doi.org/10.1093/clinchem/43.4.619.
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Abstract We have developed a systematic thin-layer chromatographic (TLC) technique for detecting and identifying drugs and drug metabolites on 10-cm-long silica-gel plates with organic binder (fluorescent indicator); a computer program (SPOT CHEK) assists in matching the data from a particular chromatogram with those obtained for known drugs recovered from serum, urine, or other specimens. The plates are developed in a single mobile phase. Visualization and detection reagents used to characterize unknowns include fluorescamine, ferric chloride/perchloric acid/nitric acid, Dragendorff, Marquis, Mandelin, and iodinated Dragendorff solutions, 254 nm ultraviolet light, and vapor from chlorine or hydrochloric acid. Detection limits of 5–200 ng per sample spot were obtained for drugs in the database. The computer program database is based on nine reaction responses plus the plate zone locations for 243 drug substances but requires entry of only one TLC property to generate a matching list. We ran the program with an IBM-compatible 386/486 PC using an MS-DOS operating system (version 6.2).
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Asmara, Anjar Purba. « A PRELIMINARY STUDY OF INVESTIGATING OF COMPOUND GROUP CONTAINED IN ETHANOLIC EXTRACT OF MAHAGONY (Swietenia mahagoni L. Jacq.) SEEDS RELATED TO Α-GLUCOSIDASE INHIBITION ». Jurnal Natural 18, no 2 (6 juin 2018) : 49–56. http://dx.doi.org/10.24815/jn.v18i2.9236.
Texte intégralRésumé :
A preliminary study to determine the group of compound contained in the ethanolic extract of mahagony (Swietenia mahagoni L. Jacq.) seeds and its inhibitory activity to a-glucosidase enzyme has been done. The information from this study will be used in the further investigation about the specific constituents related to the bioactivity. The seed was grounded and then extracted with ethanol by maceration technique. The crude extract was separated with liquid-liquid extraction by using n-hexane, ethyl acetate, and methanol as the solvents. The best eluent for isolation, chloroform:ethanol (1:1), was determined by thin layer chromatography while alumina as stationary phase. The isolation step with column chromatography gave two types of isolates, yellow and colorless isolate. In order to get information about the compound, the crude extract was subjected to phytochemical assignment and the isolate with the better activity was analyzed by infrared spectroscopy. The inhibitory activity for the yellow isolate with IC50 as 19.345 ppm was better than the colorless isolate. Therefore, the IR spectroscopy assay was subjected to the yellow isolate. Based on the comparison IR spectra with literatures, it has suggested that the yellow isolate contains tetranortriterpenoid or limonoid group.Keywords: Swietenia mahagoni L. Jacq., diabetes type 2, a-glucosidase, tetranortriterpenoidREFERENCE World Health Organization. Global report on diabetes. http://www.who.int. Accessed on 18 July 2017.Kementerian Kesehatan Republik Indonesia. 2014. Situasi dan analisis diabetes. Jakarta: Pusat Data dan Informasi Kemenkes RI.Dutta, M., Raychaudhuri, U., Chakroborty, R., and Maji, D. 2011. Role of diet and plants on diabetic patients - a critical appraisal. Science and Culture. 77 (3–4).Eid, A.M.M., Elmarzugi, N.A., and El-Enshasy, H.A. 2013. A Review on the phytopharmacological effect of Swietenia macrophylla, Int J Pharm Pharm Sci. 5 (3): 47-53.Bera, T.K., Chatterjee, K., Jana, K., Ali, K.M., De, D., Maiti, M., and Ghosh, D. 2012. Antihyperglycemic and antioxidative effect of hydro-methanolic (2:3) extract of the seed of Swietenia mahagoni (L.) Jacq. in streptozotocin-induced diabetic male albino rat: an approach through pancreas. Genomic Medicine, Biomarkers, and Health Sciences. 4: 107-117.Li, D.D, Chen, J.H, Chen, Q, Li, G.W, Chen, J, and Yue, J.M. 2005. Swietenia mahagony extract shows agonistic activity to PPAR-γ and gives ameliorative effects on diabetic db/db mice. Acta Pharmacol Sinica. 26 (2): 220-222.Sathish, R., Natarajan, K., and Selvakumar, S. 2010. Antidiabetic activity of Swietenia mahagoni seed powder in alloxan induced diabetic mice. Research J. Pharmacology and Pharmacodynamics. 2(4): 296-299.Wresdiyati, T., Sa’diah, S., and Winarto, A., Febriyani, V. 2015. Alpha-glucosidase inhibition and hypoglycemic activities of Sweitenia mahagoni seed extract. HAYATI Journal of Biosciences. 22 (2): 73-78.Sukardiman, Riza, N.F., Rakhmawati, Studiawan, H., Mulja, H.S., and Rahman, A. 2013. Hypoglycemic activity of 96% ethanolic extract of Andrographis paniculata Nees. and Swietenia mahagoni Jacq. combination, E-Journal Planta Husada,. 1.Masitha, M. 2011. Skrining aktivitas penghambatan enzim α-glukosidase dan penapisan fitokimia dari beberapa tanaman obat yang digunakan sebagai antidiabetes di indonesia. Skripsi. FMIPA UI.Aliyan, A.H. 2012. Uji penghambatan aktivitas alfa-glukosidase dan identifikasi golongan senyawa kimia dari fraksi aktif ekstrak biji mahoni (Swietenia macrophylla King). Skripsi. FMIPA UI.Ibrahim, M.A., Koorbanally, N.A., and Islam, M.S. 2014. Antioxidative activity and inhibition of key enzymes linked to type-2 diabetes (a-glucosidase and a-amylase) by Khaya senegalensis. Acta Pharm. 64: 311–324.Harborne, J. B. 1984. Phytochemical methods: a guide to modern techniques of plant analysis. New York: Chapman and Hall.Kadota, S., Marpaung, L., Tohru, K., and Ekimoto, H. 1990. Constituents of the seeds of Switenia mahagoni JACQ. I. isolation, structures, and 1H- and 13C-nuclear magnetic resonance signal assignments of new tetranorterpenoids related to swietenine and swietenolide. Che. Pharm. Bull. 38(3): 639–651.Rahman, A. K. M. S., Chowdhury, A. K. A., Ali, H.A., Raihan, S.Z, Ali, M.S., Nahar, L., and Sarker, S.D. 2009. Antibacterial activity of two limonoids from Swietenia mahagoni against multiple-drug-resistant (MDR) bacterial strains. J Nat Med. 63: 41–45.Yadav, L.D.S. 2005. Organic spectroscopy. Allahabad: Kluwer Academic Publishers.Dewanjee, S., Maiti, A., Das, A.K., Mandal, S.C., and Dey, S.P. 2009. Swietenine: a potential oral hypoglycemic from swietenia macrophylla seed. Fitoterapia. 80: 249–251.Maiti, A., Dewanjee, S., and Sahu, R. 2009. Isolation of hypoglycemic phytoconstituent from Swietenia macrophylla Seeds, Phytother. Res. 23: 1731–1733.Marliana, S.D., Suryanti, V., and Suyono. 2005. Skrining fitokimia dan analisis kromatografi lapis tipis komponen kimia buah labu siam (Sechium edule Jacq. Swartz.) dalam ekstrak etanol, Biofarmasi. 3 (1): 26-31.Nurhayati, Siadi, K., and Harjono. 2012. Pengaruh konsentrasi natrium benzoat dan lama penyimpanan pada kadar fenolat total pasta tomat, Indo. J. Chem. Sci. Vol. 1 (2): 158-163.Siadi, K. 2012. Ekstrak bungkil biji jarak pagar (Jatropha curcas) sebagai biopestisida yang efektif dengan penambahan larutan NaCl. Jurnal MIPA. 35 (1): 80-81.Klein, D.R. 2012. Organic chemistry. New Jersey: John Wiley & Sons.Pavia, D.L., Lampman, G.M., and Kriz, G.S. 2001. Introduction to spectroscopy. London: Thomson Learning.Minaeva, V.A., Minaev, B.F., Baryshnikov, G.V., Romeyko, O.M., and Pittelkow, M. 2013. The FTIR spectra of substituted tetraoxa[8]circulenes and their assignments based on DFT calculations, Vibrational Spectroscopy. 65: 147–158.Mootoo, B.S., Ali, A, Motilal, R, Pingal, R, Ramlal, A, Khan, A, Reynolds, W.F, and McLean, S. 1999. Limonoids from Swietenia macrophylla and S. aubrevilleana. J. Nat. Prod. 62: 1514-1517.Lin, B.D., Yuan, T., Zhang, C.R., Dong, L., Zhang, B., Wu, Y., and Yue, J.M. 2009. Structurally diverse limonoids from the fruits of Swietenia mahagoni. J. Nat. Prod. 72: 2084–2090.Cheng, Y.B., Chien, Y.T., Lee, J.C., Tseng, C.K., Wang, H.C., Lo, W., Wu, Y.H., Wang, S.Y., Wu, Y.C., and Chang, F.R. 2014. Limonoids from the seeds of Swietenia macrophylla with inhibitory activity against dengue virus 2. J. Nat. Prod. dx.doi.org/10.1021/np5002829.Zhang, W.M., Liu, J.Q., Deng, Y.Y., Xia, J.J., Zhang, R.N., Li, Z.R., and Qiu, M.H. 2014. Diterpenoids and limonoids from the leaves and twigs of Swietenia mahagoni. Nat. Prod. Bioprospect. 4:53–57.Ma, Y.Q., Jiang, K., Deng, Y., Guo, L., Wan, Y.Q., and Tan, C.H. 2017. Mexicanolide-type limonoids from the seeds of Swietenia macrophylla, Journal of Asian Natural Products Research, DOI: 10.1080/1028-6020.2017.1335715.Zang, Y., amd Xu, H. 2017. Recent progress in the chemistry and biology of limonoids. RSC Adv. 7: 35191–35220.Tan, Q.G., and Luo, X.D. 2011. Meliaceous limonoids: chemistry and biological activities. Chem. Rev., 111, 7437–7522.Fang, X., Di, Y. T, and Hao, X. J. 2011. The advances in the limonoid chemistry of the Meliaceae family. Current Organic Chemistry. 15: 1363-1391.Taylor, D. A. H. The chemistry of the limonoids from meliaceae. https://link.spri-nger.com/book-series/126. Accessed on 21 July 2017.Zang, Y., amd Xu, H. 2017. Recent progress in the chemistry and biology of limonoids. RSC Adv. 7: 35191–35220.
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Vyletělová, Petra, et Aleš Froňka. « CONTINUOUS RADON-IN-WATER MONITORING—COMPARISON OF METHODS UNDER LABORATORY CONDITIONS AND RESULTS OF IN SITU MEASUREMENTS ». Radiation Protection Dosimetry 186, no 2-3 (décembre 2019) : 406–12. http://dx.doi.org/10.1093/rpd/ncz241.
Texte intégralRésumé :
Abstract The extraction of dissolved radon from water to gas is the most common way to measure radon concentration in water continuously. The response delay of continuous radon-in-water detection system (continuous monitor + equilibrator) is influenced by the response time of the continuous monitor and a rate of an establishment of equilibrium in the equilibrator (exchanger unit). Two types of equilibrators were used in performed experiments to compare the response time of various detection systems—RAD AQUA that uses water spraying and equilibrator with ACCUREL® PP membrane that enables radon diffusion. Each of these was connected to the continuous monitor RAD7 or RM-3. The response delay after turning on the water flow through the equilibrator was determined. The fastest detection system was RAD7 + RAD AQUA that was subsequently tested during the insitu measurement of thermal water in the healing spa and water sources near Cheb and České Budějovice.
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Wang, Zhe, Itsushi Uno, Kazuo Osada, Syuichi Itahashi, Keiya Yumimoto, Xueshun Chen, Wenyi Yang et Zifa Wang. « Spatio-Temporal Variations of Atmospheric NH3 over East Asia by Comparison of Chemical Transport Model Results, Satellite Retrievals and Surface Observations ». Atmosphere 11, no 9 (25 août 2020) : 900. http://dx.doi.org/10.3390/atmos11090900.
Texte intégralRésumé :
Atmospheric ammonia (NH3) plays an important role in the formation of secondary inorganic aerosols, the neutralization of acid rain, and the deposition to ecosystems, but has not been well understood yet, especially over East Asia. Based on the GEOS-Chem model results, the IASI satellite retrievals, the in-site surface observations of a nationwide filter pack (FP) network over Japan and the long-term high resolution online NH3 measurements at Fukuoka of western Japan, the spatio-temporal distributions of atmospheric NH3 over East Asia was analyzed comprehensively. A significant seasonal variation with a summer peak was found in all datasets. Comparison between the satellite retrievals and model simulations indicated that the IASI NH3 vertical column density (VCD) showed good consistency with GEOS-Chem results over North and central China, but had large differences over South China due to the effect of clouds. Over the Japan area, GEOS-Chem simulated NH3 concentrations successfully reproduced the spatio-temporal variations compared with in-situ observations, while IASI NH3 VCD retrievals were below or near the detection limit and difficult to obtain a reasonable correlation for with model results. The comprehensive analysis indicated that there were still some differences among different datasets, and more in-situ observations, improved satellite retrievals, and high-resolution model simulations with more accurate emissions are necessary for better understanding the atmospheric NH3 over East Asia.
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Mashayekhi, R., et J. J. Sloan. « Effects of aerosols on precipitation in north-eastern North America ». Atmospheric Chemistry and Physics 14, no 10 (26 mai 2014) : 5111–25. http://dx.doi.org/10.5194/acp-14-5111-2014.
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Abstract. The changes in precipitation in north-eastern North America caused by chemistry – and particularly anthropogenic aerosols – are investigated using the Weather Research Forecasting with Chemistry (WRF/Chem v3.2) model. The simulations were carried out for a five-month period from April to August 2009. The model results show that non-negligible changes in both convective and cloud-resolved (non-convective) precipitation are caused by chemistry and/or aerosols over most parts of the domain. The changes can be attributed to both radiative and microphysical interactions with the meteorology. A chemistry-induced change of approximately −15% is found in the five-month mean daily convective precipitation over areas with high convective rain; most of this can be traced to radiative effects. Total convective rain is greater than total non-convective rain in the domain, but a chemistry-induced increase of about 30% is evident in the five-month mean daily non-convective precipitation over the heavily urbanized parts of the Atlantic coast. The effects of aerosols on cloud microphysics and precipitation were examined for two particle size ranges, 0.039–0.1 μm and 1–2.5 μm, representing the nucleation and accumulation modes respectively. Strongly positive spatial correlation between cloud droplet number and non-convective rain are found for activated (cloud-borne) aerosols in both size ranges. Non-activated (interstitial) aerosols have a positive correlation with cloud droplet number and non-convective rain when they are small and an inverse correlation for larger sizes.