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Littérature scientifique sur le sujet « Case control design »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 22 juin 2025

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Articles de revues sur le sujet "Case control design"

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POLIVKA, BARBARA J., and JENNIE T. NICKEL. "Case-Control Design." Nursing Research 41, no. 4 (1992): 250???254. http://dx.doi.org/10.1097/00006199-199207000-00013.

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Støer, NC, A. Salim, K. Bokenberger, I. Karlsson, and M. Reilly. "Is the matched extreme case–control design more powerful than the nested case–control design?" Statistical Methods in Medical Research 28, no. 6 (2018): 1911–23. http://dx.doi.org/10.1177/0962280218778624.

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For time-to-event data, the study sample is commonly selected using the nested case–control design in which controls are selected at the event time of each case. An alternative sampling strategy is to sample all controls at the same (pre-specified) time, which can either be at the last event time or further out in time. Such controls are the long-term survivors and may therefore constitute a more ‘extreme’ comparison group and be more informative than controls from the nested case–control design. We investigate this potential information gain by comparing the power of various ‘extreme’ case–control designs with that of the nested case–control design using simulation studies. We derive an expression for the theoretical average information in a nested and extreme case–control pair for the situation of a single binary exposure. Comparisons reveal that the efficiency of the extreme case–control design increases when the controls are sampled further out in time. In an application to a study of dementia, we identified Apolipoprotein E as a risk factor using a 1:1 extreme case–control design, which provided a hazard ratio estimate with a smaller standard error than that of a 2:1 nested case–control design.

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Fletcher, Astrid E. "Case-Control Design: Making the Case." American Journal of Ophthalmology 149, no. 4 (2010): 540–42. http://dx.doi.org/10.1016/j.ajo.2009.08.019.

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Bangdiwala, Shrikant I. "Basic epidemiology research designs II: case-control design." International Journal of Injury Control and Safety Promotion 26, no. 2 (2019): 200–202. http://dx.doi.org/10.1080/17457300.2019.1591663.

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Suissa, Samy. "THE CASE-TIME-CONTROL DESIGN." Epidemiology 6, no. 3 (1995): 248–53. http://dx.doi.org/10.1097/00001648-199505000-00010.

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Suissa, Samy. "The Case-Time-Control Design." Epidemiology 9, no. 4 (1998): 441–45. http://dx.doi.org/10.1097/00001648-199807000-00016.

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Salton, Aurélio T., Zhiyong Chen, and Minyue Fu. "Improved Servomechanism Control Design – Nonswitching Case." IFAC Proceedings Volumes 44, no. 1 (2011): 8614–19. http://dx.doi.org/10.3182/20110828-6-it-1002.00453.

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Wacholder, Sholom. "Design issues in case-control studies." Statistical Methods in Medical Research 4, no. 4 (1995): 293–309. http://dx.doi.org/10.1177/096228029500400403.

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Levin, Kate Ann. "Study design V. Case–control studies." Evidence-Based Dentistry 7, no. 3 (2006): 83–84. http://dx.doi.org/10.1038/sj.ebd.6400436.

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Pfeiffer, Ruth M., and Nilanjan Chatterjee. "On a Supplemented Case-Control Design." Biometrics 61, no. 2 (2005): 584–90. http://dx.doi.org/10.1111/j.1541-0420.2005.00319.x.

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Thèses sur le sujet "Case control design"

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Zhang, Han. "Information Driven Control Design: A Case for PMSM Control." Cleveland State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=csu1515408555890069.

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鄧國樑 and Kwok-Leung Tang. "Urban design control: case study in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31980491.

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Tang, Kwok-Leung. "Urban design control : case study in Hong Kong /." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25799411.

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Peterson, Lloyd G. "Lean/flow design event a manufacturing cost reduction case study /." Online version, 2004. http://www.uwstout.edu/lib/thesis/2004/2004petersonl.pdf.

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Zammit, A. "Urban design quality through development control : the case of Malta." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1390793/.

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Taking the island of Malta as a case study, this research questions the role of development control in delivering urban design quality. Authors have acknowledged the significance of this relationship. However, few studies have tried to assess both sides of the story, focusing instead on the study of either the planning process or final design outcome in isolation. These studies have also generally tended to rely exclusively on either qualitative or quantitative research methods. The Maltese plan‐led discretionary planning system is experiencing interesting times. Recent documents produced by the Kamra tal‐Periti, the Chamber of Architects and Civil Engineers, together with central Government’s National Environment Policy, point to the need for an informed debate on urban design quality in the built environment. Central Government also initiated a planning reform in 2010, which to date has remained focused on the reform of planning procedures within the Malta Environment and Planning Authority, rather than on quality targets. These are also challenging times. The intense residential development that characterised the past decades occurred at the expense of broader qualitative considerations. Its consequences have been compounded by the restrictive spirit of current policy tools, their inadequacy in addressing urban design issues, and the approach of officers and decision‐makers in their regard. It is thus the optimal time to study the Maltese planning system. This research explores the multifarious debates surrounding development control, urban design quality and the Maltese planning context. Using a mixed four-stage methodology comprising both quantitative and qualitative research tools, it subsequently develops ‘process’- and ‘product’-related analytical frameworks that respectively assess key themes within the planning process and the quality of urban design outcome on the ground. At the concluding stage, the research draws these frameworks together to determine their possible relationship and provide recommendations to stimulate a rethinking of planning practice.

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Hein, Misty. "Occupational Cohort Studies and the Nested Case-Control Study Design." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1250795434.

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Keogh, Ruth Heather. "Several aspects of the design and analysis of case-control studies." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442567.

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Loizides, Charalambos. "Extensions of the case-control design in genome-wide association studies." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:89e057e5-d30f-4125-b210-14d1f2aa37c1.

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The case-control design is one of the most commonly used designs in genome- wide asociation studies. When we increase the sample size of either the controls or, more importantly, the cases, the power of whatever test we use will certainly increase. However increasing the sample size, means that addi- tional individuals need to be genotyped and this implies extra financial costs. However, nowadays with the emergence of genetic studies, a large number of genetic data are available at low or no extra cost. Even though those data may not be completely relevant to the current study, they can still be used to increase the probability to identify true associations. Furthermore, additional information, non-necessarily genetic, can also be used to improve the power of a method. In this thesis we extend the case-control design in order to take ad- vantage of such types of additional data and/or information. We discuss three designs; the case-cohort-control, the kin-cohort and the super-case– case–control–super-control designs. For each of these, we present methods that are adjusted or modified versions of standard case-control methods but we also propose novel ones developed with those extended designs in mind. Ultimately, we describe how those methods can be used in order to increase the power of association tests, especially compared to similar methods of the case-control design.

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Kara, Mohamed Mohamed. "Design and control of UAV systems : a tri-rotor UAV case study." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/design-and-control-of-uav-systems-a-trirotor-uav-case-study(2b492c93-6b35-4317-ba6d-4c5e805d38fd).html.

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The field of UAV systems is an active research area with potential for development and enhancement in various perspectives. This thesis investigates different issues related to the design, operation and control of UAV systems with a focus on the application side of each proposed solution where the implementation side and applicability of the proposed solutions are always considered with high priority. The thesis discusses unmodeled actuator dynamics and their effect on UAV systems when using feedback linearisation to linearize nonlinear models of UAVs. The analysis shows potential risk when implementing feedback linearisation and neglecting actuator dynamics even for first order actuator system. A solution algorithm of two stage feedback linearisation is proposed to handle actuator dynamics and linearize the main dynamics of the system. In the field of design and operation of UAVs, this thesis proposes a systematic design procedure for electric propulsion systems that are widely used in UAVs. The design procedure guides the designer step by step to achieve minimum propulsion system weight or maximum flight time or a trade off between the two factors from the supplied solution sets. On the navigation side, the thesis proposes a new indoor navigation system that is easy to implement and less costly compared with other indoor navigation systems. The proposed system can be classified under computer-vision based navigation systems, however, it needs less information and less computational capacity. The thesis also contributes to the structure design of UAV systems by producing a novel tri-rotor UAV platform. The proposed UAV is novel in structure and design and has a centralized control system that stabilizes and tracks both rotational and transitional motion of the vehicle simultaneously.

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Hernandez, Ivan Adolfo Valdovinos. "The Role of Subsidiaries in Control System Design : A Case Based Analysis." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508824.

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Livres sur le sujet "Case control design"

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Armenian, Haroutune K. The case-control method: Design and applications. Oxford University Press, 2009.

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O'Hare, Elspeth, and Mike Prince. Systems and control. Films for the Humanities and Sciences, 2006.

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Rohin, Mhatre, ed. Quality by design for biopharmaceuticals: Principles and case studies. Wiley, 2009.

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Perry, Randy C. The business case for design for Six Sigma. Prentice Hall, 2006.

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Murphy, James Padraig. Strategic control systems design development and implementation: A case study. University College Dublin, Graduate School of Business, 1998.

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Jen, Erica. Robust design: Repertoire of biological, ecological, and engineering case studies. Edited by Jen Erica. Oxford University Press, 2005.

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Cheng, Shulin. Nonparametric analysis of data obtained under case-cohort design. [Columbia University], 1993.

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Finch, Byron J. Planning and control system design: Principles and cases for process manufacturers. American Production and Inventory Control Society, 1987.

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Center, Ames Research, ed. The development of the CONDUIT advanced control system design and evaluation interface with a case study application to an advanced fly by wire helicopter design. National Aeronautics and Space Administration, Ames Research Center, 1999.

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J, Knox, and George C. Marshall Space Flight Center., eds. Computer-Aided System Engineering and Analysis (CASE/A) programmer's manual, version 5. National Aeronautics and Space Administration, Marshall Space Flight Center, 1996.

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Chapitres de livres sur le sujet "Case control design"

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Fabricant, Peter D. "Case-Control Studies." In Practical Clinical Research Design and Application. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-58380-3_9.

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Holmes, Laurens. "Case-Control (Comparison/Non-case) Design." In Applied Epigenomic Epidemiology Essentials. Routledge, 2023. http://dx.doi.org/10.4324/9781003094487-11.

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Hyde, Richard Alden. "A Multivariable Design Case Study." In H∞ Aerospace Control Design. Springer London, 1995. http://dx.doi.org/10.1007/978-1-4471-3049-9_3.

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Phadke, Madhav S. "Design Optimization Case Studies." In Quality Control, Robust Design, and the Taguchi Method. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-1472-1_10.

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Manabe, Shunji, and Young Chol Kim. "Advanced Controller Design: Case Studies." In Coefficient Diagram Method for Control System Design. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-0546-8_4.

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Robinett, Rush D., and David G. Wilson. "Case Study #1: Control Design Issues." In Understanding Complex Systems. Springer London, 2011. http://dx.doi.org/10.1007/978-0-85729-823-2_6.

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Jesdinsky, H. J. "The Design of Case-Control Studies." In Epidemiological Concepts in Clinical Pharmacology. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71043-8_5.

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Hoshino, Yuichi. "Design of a Case Control Study." In Orthopaedic Sports Medicine. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-030-65430-6_117-1.

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Brown, Hawkins. "CASE STUDY: Research by Design: The Gantry." In Intelligent Control: Disruptive Technologies. RIBA Publishing, 2021. http://dx.doi.org/10.4324/9781003212751-12.

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Li, Angui, and Risto Kosonen. "Case Study and Design of Kitchen Ventilation." In Kitchen Pollutants Control and Ventilation. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6496-9_9.

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Actes de conférences sur le sujet "Case control design"

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Persson, Niklas, Mojtaba Kaheni, and Alessandro V. Papadopoulos. "A Direct Data-Driven Control Design for Autonomous Bicycles." In 2024 IEEE 20th International Conference on Automation Science and Engineering (CASE). IEEE, 2024. http://dx.doi.org/10.1109/case59546.2024.10711696.

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Liu, Zhili, Xingcheng Huang, Shuwang Du, and Mingxuan Sun. "A New Sensorless Design for PMLSM Servo Control System." In 2009 IITA International Conference on Control, Automation and Systems Engineering, CASE 2009. IEEE, 2009. http://dx.doi.org/10.1109/case.2009.127.

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Dowell, J. "Generative case structure for training scenarios." In People in Control. Human Factors in Control Room Design. Institution of Engineering and Technology, 2001. http://dx.doi.org/10.1049/cp:20010452.

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Shi, Yanping, and Yifei Shi. "Design of a New Magnetoelastic Stress Sensor." In 2009 IITA International Conference on Control, Automation and Systems Engineering, CASE 2009. IEEE, 2009. http://dx.doi.org/10.1109/case.2009.124.

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Yu, Ying, and Ziran Zhang. "Contemporary Social Design Principles in HCI Design." In 2011 International Conference on Control, Automation and Systems Engineering (CASE). IEEE, 2011. http://dx.doi.org/10.1109/iccase.2011.5997675.

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Nunna, Kameswarie, Nicolas Gautier, Sebastian Malack, and Mischa Kim. "Model-based design for rapid controller prototyping of Furuta pendulum: A case study using low-cost hardware." In 2016 UKACC 11th International Conference on Control (CONTROL). IEEE, 2016. http://dx.doi.org/10.1109/control.2016.7737641.

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Chuang, Li. "Information System Design of Finance Sale Management of SME." In 2009 IITA International Conference on Control, Automation and Systems Engineering, CASE 2009. IEEE, 2009. http://dx.doi.org/10.1109/case.2009.48.

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Xiangru, Meng, and Song Wei. "Network Design Based on Closed-Loop Reverse Logistics Recycling." In 2009 IITA International Conference on Control, Automation and Systems Engineering, CASE 2009. IEEE, 2009. http://dx.doi.org/10.1109/case.2009.11.

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Fang, Anan, Maojin Wang, and Liping Luo. "ZigBee-Based Intelligent Home Bus Ethernet Transmission Software Design." In 2009 IITA International Conference on Control, Automation and Systems Engineering, CASE 2009. IEEE, 2009. http://dx.doi.org/10.1109/case.2009.27.

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Park, C. H., S. K. Choi, and S. Y. Ham. "Design and control for hybrid magnetic thrust bearing for turbo refrigerant compressor." In 2011 IEEE International Conference on Automation Science and Engineering (CASE 2011). IEEE, 2011. http://dx.doi.org/10.1109/case.2011.6042409.

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Rapports d'organisations sur le sujet "Case control design"

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Mwebe, Robert, Chester Kalinda, Ekwaro A. Obuku, et al. Epidemiology and effectiveness of interventions for Foot and Mouth Disease in Africa: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0039.

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Review question / Objective: What is the epidemiology and effectiveness of control measures for foot and mouth disease in African countries?’ PICOS: Description of elements Population/ problem/Setting: Artiodactyla (cloven ungulates), domestic (cattle, sheep, goats, and pigs), camels and wildlife (buffaloes, deer, antelope, wild pigs, elephant, giraffe, and camelids) affected by Foot and Mouth Disease (FMD) or Hoof and Mouth Disease (HMD) caused by the Foot and Mouth Disease Virus (FMDV) in Africa. Intervention: Prevention measures: vaccination, ‘biosafety and biosecurity’, sensitization of the public. Control measures: quarantine, movement control, closure of markets and stock routes, mouth swabbing of animals with infected materials (old technique that is no long applicable), culling, mass slaughter, stamping out and any other interventions or control measures generally accepted by the ‘community of practice’ of animal health practitioners. Comparator: areas that did not have any control activities for FMD, in head-to-head comparisons in the same study. Outcome: epidemiological outcomes: incidence, prevalence, patterns or trends, clinical symptoms, and risk factors. Effectiveness outcomes: success, and usefulness of the interventions measured as averted deaths, illness and infections, and costs associated with the interventions (cost–effectiveness). Study design: epidemiological designs include cohort design for incidence, cross sectional for prevalence and case-control for clinical symptoms and risk factors. Interventional designs include randomized controlled trials, cluster randomized trials, quasi-experimental designs – controlled before and after, interrupted time series, [regression discontinuity design, difference-in-difference, and propensity score matching]. Timelines: 1900 – 2022.

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Díaz, Lina M., Déborah Martínez Villarreal, Karina Olenka Stella Marquez Guerra, and Carlos Scartascini. Combating Vaccine Hesitancy: The Case of HPV Vaccination. Inter-American Development Bank, 2025. https://doi.org/10.18235/0013410.

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Cervical cancer, primarily caused by persistent Human Papillomavirus (HPV) infection, remains one of the leading causes of cancer-related deaths among women in developing countries. Although HPV vaccines are widely available in these regions, vaccine uptake remains persistently low. To address behavioral barriers contributing to this low demand, we evaluated the effectiveness of a behaviorally informed SMS campaign targeting parents in Cali, Colombia. Our study included 15,231 parents, who were randomized into six groups: control, placebo, and four behaviorally informed treatment groups, forming a large-scale study of text-based nudges. Participants received tailored messages over eight weeks. The intervention yielded significant increases in vaccination rates, with improvements ranging from 34% to 55%. Furthermore, the economic analysis demonstrated that the intervention generated between USD 3.6 and USD 5.75 in economic benefits for every dollar spent, primarily due to prevented deaths. These findings underscore the potential of behavioral interventions in enhancing HPV vaccination rates among parents and emphasize the cost-effectiveness and relative success of each intervention strategy. This study provides actionable insights for public health officials to design targeted strategies that address vaccination disparities and promote preventive healthcare practices.

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Camenzind, Lauren, Molly Kafader, Rachel Schwam, Mikayla Taylor, Zoie Wilkes, and Madison Williams. Space Retrieval Training for Memory Enhancement in Adults with Dementia. University of Tennessee Health Science Center, 2021. http://dx.doi.org/10.21007/chp.mot2.2021.0013.

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The final portfolio contains 8 research articles from national and international journals. Study designs include one systematic review, one randomized control trial with pretest-posttest design, three small-scale randomized control trials, one quasi-experimental study with no control, one time-series study, and one case study. All studies relate directly to components of the evidence-based practice question and will be used to draft new recommendations for implementation regarding spaced retrieval training for memory enhancement in adults with dementia. Seven out of the eight articles looked at the effects of SR techniques on functional tasks. Articles looked at eating difficulty (1), independent use of walkers (1), iADL function (3), use of technology (1), and ADL function (1). One out of eight articles looked at benefits of spaced retrieval techniques on episodic memory, which is not necessarily a functional task, but is needed to perform functional tasks.

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Brewer, Joseph, Massimo Capoccia, Dirk Maybauer, Roberto Lorusso, Justyna Swol, and Marc Maybauer. The ProtekDuo Dual Lumen Cannula as Temporary Acute Mechanical Support for Right Heart Failure: A Protocol for a Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.9.0026.

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Review question / Objective: Participants: Adult patients with right ventricular failure; Intervention: Right ventricular assist device with ProtekDuo cannula; Comparison: Control group of medical management or another type of RVAD (if available); Outcomes: Effectiveness of treatment in terms of survival and complications; Study design: Randomized controlled trials, prospective cohort studies, retrospective cohort studies, case series with >/=5 patientsProspective and retrospective cohort studies, case series of >/= 5 patients. Condition being studied: Right ventricular failure. Information sources: Databases: MEDLINE, Embase, Scopus.

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Wenren, Yonghu, Joon Lim, Luke Allen, Robert Haehnel, and Ian Dettwiler. Helicopter rotor blade planform optimization using parametric design and multi-objective genetic algorithm. Engineer Research and Development Center (U.S.), 2022. http://dx.doi.org/10.21079/11681/46261.

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In this paper, an automated framework is presented to perform helicopter rotor blade planform optimization. This framework contains three elements, Dakota, ParBlade, and RCAS. These elements are integrated into an environment control tool, Galaxy Simulation Builder, which is used to carry out the optimization. The main objective of this work is to conduct rotor performance design optimizations for forward flight and hover. The blade design variables manipulated by ParBlade are twist, sweep, and anhedral. The multi-objective genetic algorithm method is used in this study to search for the optimum blade design; the optimization objective is to minimize the rotor power required. Following design parameter substitution, ParBlade generates the modified blade shape and updates the rotor blade properties in the RCAS script before running RCAS. After the RCAS simulations are complete, the desired performance metrics (objectives and constraints) are extracted and returned to the Dakota optimizer. Demonstrative optimization case studies were conducted using a UH-60A main rotor as the base case. Rotor power in hover and forward flight, at advance ratio 𝜇𝜇 = 0.3, are used as objective functions. The results of this study show improvement in rotor power of 6.13% and 8.52% in hover and an advance ratio of 0.3, respectively. This configuration also yields greater reductions in rotor power for high advance ratios, e.g., 12.42% reduction at 𝜇𝜇 = 0.4.

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Abbott, Pamela, Dickson Malunda, and Ismael Byaruhanga. Assessing the Impact and Scalability of Participatory Homegrown Programs on Reducing and Redistributing Unpaid Care Work among Women in Rwanda: A Case of Reseaux des Femmes' Unpaid Care Work Project in Rwanda: Baseline Report. Centre for Global Development, University of Aberdeen, 2023. http://dx.doi.org/10.57064/2164/21125.

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This report provides a descriptive overview of the quantitative baseline data collected in January and February 2022 for a research project evaluating a complex social intervention to reduce and redistribute women’s unpaid care work (UCW) in Rwanda using homegrown solutions. The intervention aims to reduce and redistribute UCW undertaken by women in Rwanda's rural areas, thereby improving their quality of life and increasing their empowerment. The findings discussed in this report are from a survey of intervention and control households and 7-day time diaries completed by husbands and wives in each household, with some illustrative material from simultaneous qualitative research. The research design for the project is a cluster trial informed by critical realism (CRCT) , combining quantitative and qualitative research methods to explain what works for whom under what circumstances. The intention is not just to identify the changes that can be attributed to the intervention but to develop explanatory theories of why the changes took place (Danermark et al., 2019; Porter et al., 2017; Porter and O’Halloran, 2012). The purpose of a Working Paper at this stage of the project is mostly to describe the lives and subordination of rural women as revealed by the baseline survey and, in the process, to identify any differences between control and intervention groups which have occurred by chance and will need to be controlled statistically in the analysis of the final results.

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Zhu, Yi-Bing, Yan Yao, Yuan Xu, and Hui-Bin Huang. Nitrogen balance and Outcomes in Critically Ill Patients: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.5.0134.

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Review question / Objective: This study aimed to evaluate the impact of Nitrogen balance (NB) on prognosis in such a patient population. Condition being studied: Nitrogen balance and Outcomes in Critically Ill Patients. Eligibility criteria: 1) The study focused on the association between NB level and the mortality risk in adult (≥18 years old) patients; 2) The outcome data included any reporting form of survival data that could be extracted; and 3) The study design was limited to cohort, case-control, or RCT design.

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Biagio, M. Di, A. Fonzo, and F. Marchesani. JTM13-CAD Crack Arrestor Design for High Grade Gas Transportation Pipeline. Pipeline Research Council International, Inc. (PRCI), 2001. http://dx.doi.org/10.55274/r0011813.

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The interest of gas companies in the use of high-grade steel pipes, equivalent to X100 and higher, for the construction of long-distance gas pipelines is now a consolidated trend in the world; these pipelines are demanded to operate under extreme operating conditions, such as low temperature, high pressure and high design factor. Under this severe operating scenario the running shear fracture control can not be only assured by the inherent pipe body material self arrestability, and in this case, the use of external mechanical devices, i.e. crack arrestors, becomes mandatory as also envisaged by the draft of the new pipeline ISO standards under discussion. At the same time the knowledge available on the matter mainly dated back to the past, and the existing crack arrestor design guidelines, as those published by PRCI in the 80's, make reference to experimental experience gained on conventional, lower toughness and lower pressure gas linepipe.

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Chmielewska, Daria, Jitka Malá, Alena Kobesova, et al. Dry needling for physical therapy of scar. A protocol for a systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.1.0058.

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Review question / Objective: The research question was defined according to the PICOS criteria: P - participants of any age with a scar / keloid / hypertrophic scar. I - interventions: local management with needling, dry needling, acupuncture or combination of local needling / dry needling / acupuncture with distal acupuncture. C - comparator: local intervention (physical therapy) aimed at scar, keloid or hypertrophic scar treatment or no treatment. O - objectives: changes in pain associated with scar, keloid or hypertrophic scar. Pigmentation, vascularity, height / thickness, pliability / plasticity, itchiness of the scar area. S - study design: The articles were included based on the following inclusion criteria: full text articles in English, randomized controlled trials, clinical trials, case reports, case-series, case control studies.

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Kang, Jing, Jun Zhang, Zongsheng Tian, Ye Xu, Jiangbi Li, and Mingxina Li. The efficacy and safety of immune-checkpoint inhibitor plus chemotherapy versus chemotherapy for non-small cell lung cancer: an updated systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.5.0156.

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Review question / Objective: Population: histologically confirmed advanced NSCLC patients; Intervention: received immune-checkpoint inhibitor plus chemotherapy; Comparison:received chemotherapy; Outcome: reported OS, PFS, ORR and TRAEs; Study design: RCT. Condition being studied: Lung cancer is the primary cause of cancer-related deaths, with an estimated 2.20 million new cases and 1.79 million deaths every year, and 85% of all primary lung cancers are non-small cell lung cancer. Eligibility criteria: Studies were considered eligible if they met the following criteria: (1) being an randomized controlled trial published in English, (2) histologically confirmed advanced NSCLC patients, (3) reported OS, PFS, ORR and TRAEs, (4) the intervention group received immune-checkpoint inhibitor plus chemotherapy, while the control group received chemotherapy, (5) When numerous papers reporting the same trial were found, the most current or most complete publications were chosen. The following were the exclusion criteria: (1) duplicate articles, (2) reviews, meta-analyses, case reports, editorials and letters, (3) molecular biology or animal research, (4) retrospective or prospective observational cohort studies.

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