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Littérature scientifique sur le sujet « C05X »

Auteur : Grafiati

Publié le 9 mars 2023

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Articles de revues sur le sujet "C05X"

STINGL, G. « C058 Melanoma — Immunotherapy ». Journal of the European Academy of Dermatology and Venereology 9 (septembre 1997) : S71. http://dx.doi.org/10.1016/s0926-9959(97)89133-7.

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REITAMO, S. « C059 Immunomodulatory drugs ». Journal of the European Academy of Dermatology and Venereology 9 (septembre 1997) : S71. http://dx.doi.org/10.1016/s0926-9959(97)89134-9.

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DUPMENAGE, H. « C050 Chronic actinic dermatitis ». Journal of the European Academy of Dermatology and Venereology 9 (septembre 1997) : S69. http://dx.doi.org/10.1016/s0926-9959(97)89124-6.

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Setiawan, Ferry, Edi Sofyan et Faisal Romadhon. « ANALISIS EFEKTIVITAS TURN AROUND TIME DENGAN METODE CRITICAL PATH METHOD PADA AKTIVITAS PERAWATAN C05- CHECK PESAWAT AIRBUS 320-200 ». Teknika STTKD : Jurnal Teknik, Elektronik, Engine 7, n^o 1 (30 juillet 2021) : 50–63. http://dx.doi.org/10.56521/teknika.v7i1.273.

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Penelitian ini bertujuan untuk meningkatkan efektivitas pelaksanaan suatu aktivitas perawatan sesuai dengan task card C05-Check Pesawat Airbus 320-200, sehingga dihasilkan aktivitas perawatan yang lebih efektive terhadap jumlah waktu yang dibutuhkan dalam mengerjakan sebuah tugas kerja dari mulai awal perawatan sampai selesai atau sering di sebut Turn Around Time (TAT). Permasalahan TAT pada aktivitas perawatan C05-Check Airbus 320-200 adalah waktu TAT yang cukup lama sehingga membutuhkan biaya operasional teknisi yang cukup besar, dan adanya kerugian karena waktu tunggu operasinal pesawat pada saat perawatan. TAT pada aktivitas perawatan C05-Check Pesawat Airbus 320-200 dengan jumplah 351 task card, selama ini masih memakai standart perusahaan yang di hitung dengan metoda giant chart yaitu selama 13 hari kerja. Permasalahan yang ada mendorong penulis melakukan analisis dan perhitungan TAT pada aktivitas perawatan C05-Check Pesawat Airbus 320-200 dengan metode Critical Path Method (CPM), sebuah metode yang digunakan untuk mengidentifikasi tugas-tugas yang ada dalam sebuah aktivitas pekerjaan dan membentuk desain jaringan CPM sesuai dengan urutan dan jalur kritis pekerjaan. Hasil perhitungan Turn Around Time dengan metode (CPM) pada aktivitas perawatan C05-Check Pesawat Airbus 320-200 dengan jumlah task card 315 adalah 10,46 hari kerja, dengan jalur kritis berada pada code aktivity A-B-D-D1-D2-D3-D4-D5-D6-D7-H-I-J, pekerjaan secara seri code aktivity A-B-H-I-J, Sedangkan pekerjaan code aktivity C-D-E-F-G. Desian jarring CPM ini menghasilkan waktu perawatan yang lebih sedikit jika di bandingkan TAT standart Perusahaan yaitu 13 hari kerja. Selisih waktu penyelesaian TAT dengan metode CPM dengan Standart perusahanan adalah 2,54 hari kerja, sehingga dapat di simpulkan bahwa TAT dengan perhitungan CPM lebih efektif pada aktivitas perawatan C05-Check Air Bus 320 - 200.

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MARGUERY, M. « C055 Phototherapy for the photodermatoses ». Journal of the European Academy of Dermatology and Venereology 9 (septembre 1997) : S70. http://dx.doi.org/10.1016/s0926-9959(97)89128-3.

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HERRERO, C., et M. LECHA. « C053 The common cutaneous porphyrias ». Journal of the European Academy of Dermatology and Venereology 9 (septembre 1997) : S70. http://dx.doi.org/10.1016/s0926-9959(97)89129-5.

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EPSTEIN, J. « C054 DNA repair deficient disorders ». Journal of the European Academy of Dermatology and Venereology 9 (septembre 1997) : S70. http://dx.doi.org/10.1016/s0926-9959(97)89131-3.

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FERGUSON, J. « C052 Drug and chemical photosensitivity ». Journal of the European Academy of Dermatology and Venereology 9 (septembre 1997) : S69. http://dx.doi.org/10.1016/s0926-9959(97)90097-0.

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Jouan, N., et A. Labouche. « C058 - Molluscum contagiosum sur un tatouage ». Annales de Dermatologie et de Vénéréologie 134, n^o 1 (janvier 2007) : 58. http://dx.doi.org/10.1016/s0151-9638(07)89090-9.

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MURPHY, G. « C051 Solar urticaria — Pathogenesis and management ». Journal of the European Academy of Dermatology and Venereology 9 (septembre 1997) : S69. http://dx.doi.org/10.1016/s0926-9959(97)89126-x.

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Thèses sur le sujet "C05X"

LUPIDI, GABRIELE. « Functionalization of Cyclic Structures for Advanced Biological and Pharmaceutical Applications ». Doctoral thesis, Università degli Studi di Camerino, 2019. http://hdl.handle.net/11581/428901.

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The key components of the scaffold in pharmaceutical chemistry are ring systems, of different sizes, and are the fundamental factors of most of the drugs on the market today. Nowadays, the importance of cyclic structures is well understood by medicinal chemists, since they play a significant role in molecular properties such as the electronic distribution, three dimensionality, and molecule rigidity. They are often key factors in whole molecule properties such as lipophilicity or polarity and can determine molecular reactivity, metabolic stability, and toxicity. Cyclic structures have always fascinated organic and medicinal chemists, and many organic molecules form cycles with appealing biological properties. Research in cyclic chemistry continued to advance in synthetic methods development, conformational studies and investigation of their role for controlling biological functions. This work, carried out in the Prof. Marcantoni’s research group at the University of Camerino (Camerino, Italy) with the collaboration of Dompé S.p.A. (L’Aquila, Italy) from December 2015 to December 2018 and in the Prof. Poli’s research group from January 2018 to July 2018 at the University Pierre and Marie Curie (Paris, France), had the objective to investigate new synthetic methodologies for the functionalization of cyclic compounds, as well as the formation of cyclic structures from acyclic precursor, for advanced biological purposes. The first chapter focuses on the functionalization of the primary face of a β-cyclodextrin, in order to obtain a synthetic human receptor model, used for studying the possible interactions of this compound with a new class of biologically active compounds in development at Dompé S.p.A. The second chapter, carried out in the Poli’s research group, describes the selective C-3 functionalization trials of 2-furaldehyde and its derivatives by Directed ortho Metalation (DoM) chemistry in presence of organolithium compounds and focuses on the study of degradation products. The reaction of an alkyllithium compound with an aromatic structure bearing a Direct Metalation Group (DMG) normally leads to an ortho-metalated intermediate. Good DMGs are strong complexing or chelating groups that have the effect of increasing the kinetic acidity of protons in the ortho position. The third chapter focuses on the in-depth study of the mechanistic aspect on the formation of 5acylaminothiazoles starting from α-chloroglycinates, obtained by a new synthetic methodology developed in the Marcantoni’s research group. Finally, the fourth chapter focuses on the study of the role of Cerium trichloride in the formation of cyclic compounds via Nazarov cyclization.

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STEFANINI, NICOLA. « Optimization of Industrial Polymeric Products to Improve Quality and Reduce Environmental Impact ». Doctoral thesis, Università degli Studi di Camerino, 2019. http://hdl.handle.net/11581/428907.

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The present thesis is the result of three years’ collaboration between the University of Camerino and ELANTAS Europe Srl. The strong collaboration between university and companies allows to students like others and me to do research with an industrial approach, facing with the problematics of working life. The work was carried out among the laboratory of Organic Chemistry of Prof. Enrico Marcantoni at the University of Camerino (Camerino, Italy), the R&D laboratory of ELANTAS Europe in Ascoli Piceno (Italy) and the R&D laboratory of ELANTAS PDG INC in Saint Louis (Missouri, USA). The thesis concern the environmental impact of some industrial polymeric materials. Polymeric materials are very important in modern society: they have considerable advantages over products of other origins with lower costs with the same performance. Nevertheless, they allow some applications that some years ago would have been unthinkable (microencapsulation, shape memory materials, and many others). At the same time, environmental impact is a crucial topic strictly linked to polymeric materials (as all others materials), and to the period we are living. The production of such materials is constantly growing, exceeding the production of many others materials, and it is becoming increasingly important to find ways to produce them more efficiently and to recover waste products. The consequences of a production without limitation and control could be catastrophic for the whole world and humankind too. During my PhD, I worked on three industrial products in order to reduce their environmental impact, keeping their physical properties unchanged. After a first general introduction on polymeric materials, their uses, and their production, the second chapter concern about improving a recovery process for waste PMMA. The study allowed identifying undesirable by-products formed during the thermal depolymerization of PMMA and removing them in the consequent re-polymerization by an innovative dissolution/re-precipitation method. The third and fourth chapters deal with two coatings for wires electrical insulation, one based on polyurethanes (PU) and the other on polyesterimides (PEI). With the PU-based one, the target was to reduce the amount of loss material during the application stage and to increase the speed of application in order to reduce the energy consumption of the process. Whereas with the PEI-based enamel the purpose was to synthesized a solvent-free product using a twin-screw extruder and using recycled PET as alternative raw material to form the polyester part. The extruder technology is less energy consuming compare to the batches ones and allows working without solvents, since it can work with high viscosity materials. Moreover, the extruded product, with an additional system, can be potentially applied onto the wire with a higher thickness compare to the respective solventbased product, allowing a greater flow of current along the wire, thus improving the performance of the finished products (i.e. reducing the charging time of electrical motors).

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NGAHANG, KAMTE LANDRY STEPHANE. « Searching for effective natural products against Human African Trypanosomiasis (HAT) with special reference to African natural resources ». Doctoral thesis, Università degli Studi di Camerino, 2019. http://hdl.handle.net/11581/428679.

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For centuries, African natives have been facing various infectious tropical illnesses, among which African trypanosomiases are some of the most frequent relevant parasitic diseases. African trypanosomiases, commonly called sleeping sickness in humans (HAT; Human African Trypanosomiasis) and Nagana in domestic livestock, affect a huge number of people living in poverty in 36 sub-Saharan countries, resulting in a key socioeconomic impact. After a century of outbreaks, due to political instability and lack of funding, around 70 million people and 50 million cattle are still at risk of exposure in Africa. Trypanosomiasis is transmitted by the bite of insects from the Glossina spp (Glossinidae) and is fatal in humans, if untreated. While taking a blood meal, infected Glossina flies can spread extracellular protozoans from the species Trypanosoma brucei. There are three morphologically indistinguishable subspecies of T. brucei. The subspecies T. b. gambiense is responsible for a chronic form of the human disease, while T. b. rhodesiense causes an acute form, which more rapidly leads to death. Both subspecies are infective to humans, whereas T. b. brucei is only infective to animals. During the early stage of the disease or hemolymphatic phase, the parasite is restricted to the blood and lymph and after months or years it invades the central nervous system resulting in various neurological symptoms including sleeping disturbance. As for other neglected tropical diseases, the chemotherapeutical arsenal against HAT is based on limited, expensive and often toxic medicines that are administered parentally in a context of poverty and lack of qualified personnell in healthcare centers. The few drugs that are available are pentamidine and suramin for the early stage disease and eflornithine (also in combination with nifurtimox) and melarsoprol for the late stage when the parasite infects the brain. Overall, the situation described above highlights the critical nature of this phenomena and the urgent need to explore new sources of potentially effective and safe compounds for therapy. In this scenario the naturally-occurring products may play a crucial role as source of bioactive drug candidates. With this vision in mind, in Chapter 2 I performed a complete phytochemical analysis on both polar and volatile compounds of T. diversifolia collected from a geographically isolated population living in Dschang, Cameroon and I assessed their biological activities (antitrypanosomal and amtimicrobial activities). The main secondary metabolites occurring in the T. diversifolia methanolic extract were isolated by column chromatography and structurally elucidated by MS and NMR techniques. Tagitinins C emerged as the most active compound against T. brucei (TC221) with an IC50 value of 0.0042 μg/mL. This activity was 4.5 times better than that of the reference drug suramin. Then I analysed the chemical composition and the antimicrobial effects of the essential oil (EO) hydrodistilled from inflorescences of T. diversifolia. Results showed that T. diversifolia EO was mostly active against Staphylococcus aureus and selectively inhibited in vitro the NAD biosynthetic enzyme NadD from S. aureus (IC50 of ∼60 g/mL). Besides its extensive utilizations in the traditional medicine, the plant is believed to have a great potential in agriculture. For this reason, I decided to evaluate the T. diversifolia polar extracts against the two-spotted spider mite Tetranychus urticae (Tetranychidae), which is one of the most economically important arthropod pests worldwide. The ethyl acetate extract resulted as the most active oviposition inhibitor, with an ED50 value of 44.3 µg.cm-3 and an ED90 of 121.5 µg.cm-3. In Chapter 3, I investigated a lipophilic extract of Onosma visianii roots containing 12% of shikonin derivatives. The phytochemical investigation of the lipophilic extract resulted in the isolation of 12 naphtoquinone derivatives which were evaluated against Trypanosoma brucei. Isobutylshikonin and isovalerylshikonin emerged as the most active naphtoquinone derivatives, showing an IC50 of 3.3 and 2.7 g/mL, respectively. Furthermore, isovalerylshikonin provided an inhibition of Glossina palpalis acetylcholinesterase (gpAChE) (IC50 = 7.1 μg/mL), stronger than isobutyrylshikonin (IC50 = 91.3 μg/mL), with a significant tse-tse fly versus human selectivity (SI = 7.2). In Chapter 4, I oriented my attention to the Apiaceae family, which is a class of aromatic plants rich of EOs. Four out of nine Apiaceae EOs resulted active against T. brucei showing an IC50 in the range 2.7-10.7 g/mL. Terpinolene, one the major isolated component of these oils, was particularly active with an IC50 value of 0.035 g/mL (0.26 µM) and a selectivity index (SI) of 180. As part of the extended family of naturally-occurring products, sesquiterpenes hold promising inhibitory effects against the bloodstream forms of T. brucei. For this reason, in Chapter 5, I decided to explore the potential of Smyrnium olusatrum EOs obtained and its main oxygenated sesquiterpenes, namely germacrone, isofuranodiene, and β-acetoxyfuranoeudesm-4(15)-ene, as potential inhibitors of T. brucei. The EOs obtained efficiently inhibited the growth of parasite with IC50 ranging from 1.9 to 4.0 g/mL. Among the isolated main EOs components, isofuranodiene exhibited a significant and selective inhibitory activity against T. brucei (IC50 = 0.6 g/mL, SI = 30). In Chapter 6, I finally selected six medicinal and aromatic plants traditionally used in Cameroon to treat several disorders, including infections and parasitic diseases. Then I evaluated the activity of their EOs against T. brucei TC221 and their selectivity against Balb/3T3 cells, used as counter-screen for cytotoxicity. The most relevant outcomes showed that the EOs from A. indica, A. daniellii and E. giganteus were the most active ones, with IC50 values of 15.21, 7.65 and 10.50 g/mL, respectively. Overall, the results of my PhD thesis provided new insights into the potential of naturallyoccurring compounds as valuable sources for the development of innovative trypanocidal drugs or botanical insecticides.

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NGOUADJEU, NGNINTEDEM MICHAEL ALLIANCE. « Synthesis and Biological Evaluation of new Ligands for the Adenosine Receptors ». Doctoral thesis, Università degli Studi di Camerino, 2019. http://hdl.handle.net/11581/428735.

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Adenosine (Ado) is an endogenous nucleoside ubiquitous in mammals promoting protection and cells repair during metabolic stress conditions. Through interaction with the four Ado receptor subtypes (ARs), AR ligands have shown potential therapeutic interest for many disorders. In this work both new A2AAR agonists and A3AR antagonists were designed, synthesized and tested in vitro. Although Ado 5’-N-ethylcarboxamide derivatives like VT 7 and GCS21680 display a good affinity and selectivity for A2AAR, the development of new agonists for this receptor subtype is still a big challenge in nucleoside chemistry. In this current decade, some papers have reported that a tetrazolyl residue in 4’-position of Ado derivatives led to compounds endowed with good A2AAR affinity. Hence, in this work, compounds bearing the Nethyltetrazoyl moiety in 4’- position of the Ado ribose portion together with different arylalkylthio and arylalkylamino chains in C2-position were designed and synthesized. The new compounds were prepared using a convergent approach. To this purpose, 2,6- dichloropurine was coupled with the suitable modified sugar to afford a nucleoside which was further modified by introducing an amino group at the C6- and the suitable side chain at the C2- position. The modified sugar used in the coupling reaction was synthesized starting from the commercially available D-ribose in seven steps. The binding assay and functional study performed with the new compounds at all AR subtypes transfected on Chinese hamster ovary (CHO) cells revealed that the 2-phenylethylthio derivative was the compound endowed with the better affinity for the A2AAR/A3AR subtypes (17: Ki hA2AR = 5.8 nM; Ki hA3R = 1.2 nM). It is worthwhile to note that the presence of the ethyltetrazolyl substituent in the sugar moiety favors the interaction with the receptor respect to the ethylcarboxamido group. As expected, the new derivatives show a dual behavior at ARs, resulting A2AAR agonists and A3AR antagonists (17: IC50 at hA3AR of 8.4 nM). Furthermore, the wound healing potential of the news nucleosides was evaluated respect to VT 7, CGS21680 and epidermal growth factor (EGF, used as positive control). The compounds, 17, 19, 20, 21 and 22 showed all better wound healing potential respect to VT 7, CGS21680 and EGF. Therefore such compounds are good candidates for further investigation in in vivo model of wound healing. New A3AR antagonists were also prepared based on the observations that, the substitution of the 8-bromine atom of 8-bromo-9-ethyladenine (Ki hA2AAR = 52 nM, Ki hA3AR = 2,800 nM) with phenylacetylene shifts the preference of the resulting compound (Ki hA3AAR = 86 nM, hA2AAR= 600 nM) from A2AAR to A3AR. Hence, from these facts, three series of compounds were prepared. The first one was 8-phenylethynyladenine derivatives substituted at N-9 position with different alkyl/arylalkyl chains. The second one combines substitution on the phenyl ring of 8- phenylethynyladenine with either N-9 cyclopentyl or N9 phenethyl since they resulted being the best N-9 substituents of the first series. The third series combines a fixed para-methoxy- phenylacetylene in C-8 with either N-9 cyclopentyl or N-9 phenethyl, 2-chloro, and with different N6 substituents. The 8-arylethynyladenine derivatives substituted at 9 position with different alkyl/arylalkyl chains, and the corresponding compounds further substituted at the 2 and N6 position, were synthesized starting from commercially available adenine or 2,6- dichlorpurine in three/five steps, respectively. The results of the in vitro test reported that: N-9 cyclopentyl improved affinity while N-9 phenylethyl improved selectivity, the chlorine atom is well tolerated especially when combined with C-8 para-methoxy-phenylacetylene, the N6 substitution gave compounds with maintained selectivity in the same range of the non- substituted derivatives but with a slight decrease of the affinity. Most of the new compounds are endowed with high affinity and different degree of selectivity for the A3AR subtype. In particular, the tetrasubstituted adenine derivative 38 (Ki A3R = 8.4 nM; Ki A1R and Ki A2AR >30,000 nM) resulting the most active and selective ligand and it represents a very good ligand to study the A3AR subtype and its function.

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TOMBESI, ALESSIA. « Advanced functional coating for self-cleaning and anti-corrosion applications ». Doctoral thesis, Università degli Studi di Camerino, 2019. http://hdl.handle.net/11581/432253.

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This thesis is focused on the preparation of organic-inorganic hybrid systems with targeted properties. In particular, thesis presents the synthesis, characterization and application of two types of functional coating, which are hydrophobic / self-cleaning and anticorrosion coatings. Chapter 1 is dedicated to general introduction and the state of art of advanced functional coating. The chapter includes a brief description of the current functional market size and possible applications of functional coatings. Chapter 2 provides a general introduction of superhydrophobic coatings, their possible applications on the glass surface and methods to produce them. In the chapter 3, sol-gel methods has been describe in detail. The sol gel process by employed alkoxysilanes was used in this work to fabricate the functional coatings. Chapters 4, 5 and 6 describes the experimental works of this thesis. In the chapter 4, the solgel process and dip-coating technique were employed for the preparation of hydrophobic self-cleaning hybrid materials. The process has been optimized to obtain transparent and highly hydrophobic sol-gel coatings by using different alkoxysilane. These hybrid sol-gel coatings are a good alternative to provide anti-stick and easy-to-clean properties to glass substrates being quite easy to scale up. In the chapter 5, a method for the preparation of transparent superhydrophobic silica coatings on glass substrates via aerosol‐assisted chemical vapour deposition (AACVD) is described. A multi-layer process to produce dual scale silica nanoparticles films, by using different functional alkoxysilanes was investigated. In this study, a novel strategy to achieve highly transparent superhydrophobic glass surfaces using AACVD of alkoxysilanes, to produce surfaces with excellent durability is described. This shows great potential to obtain silica superhydrophobic films for large–scale applications Finally, in the chapter 6, a preliminary study about the protective barrier coating to protect the integrity of the silver from deleterious chemical degradation in a mirror structure is investigated. Sol-gel hybrid coating has been deposited on mirror to avoid corrosion degradation process of silver layer. Salt spray test was performed on mirror coated with hybrid coating and the results showed a no signs of corrosion on the mirror. The results indicate excellent barrier protection performance of the coating.

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Atwell, Kathryn. « Investigating the interplay between cellular mechanics and decision-making in the C. elegans germ line ». Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:a641df49-c050-460a-bda5-7231d6fa67ad.

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The behaviour of individual cells must be carefully coordinated across a tissue to achieve correct function. In particular, proliferation and differentiation decisions must be precisely regulated throughout development, tissue maintenance, and repair. A better understanding of how these processes are controlled would have implications for human health; cancer is, after all, dysregulated proliferation, while regenerative medicine relies on being able to influence cell decisions accurately. To investigate such fundamental biological processes, it is common practice to use an experimentally tractable model organism. Here, we focus on the germ line of the nematode worm C. elegans, which provides opportunities to study organogenesis, tissue maintenance, and ageing effects. Despite the advantages of this organism as a biological model, certain questions about germ cell behaviour and coordination remain challenging to address in the lab. There is therefore a need for computational models of the germ line to complement experimental approaches. In this thesis, we develop a new in silico model of the C. elegans germ line. Novel aspects include working in three dimensions, covering the late larval period, and integrating a logical model of germ cell behaviour into a wider cell mechanics simulation. Our model produces a reasonable fit to wild-type germline behaviour, and provides the first cell tracking and labelling predictions for the larval period. It also suggests two new biological hypotheses: 1) that âstretchingâ growth plays a significant role in gonadogenesis, and 2) that a feedback mechanism acts on the germ cell cycle to prevent overproliferation. Having introduced the full model, we address some technical questions arising from our work, namely: what is the effect of applying a more physically realistic force law?; and can simulation performance be improved by changing the numerical scheme? Finally, we use in silico modelling to compare a number of hypothesised germ line maintenance mechanisms. There, our results support a model with functionally equivalent germ cells undergoing at most infrequent, transient cell cycle arrests.

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Flint, Alexander John. « Geometric context from single and multiple views ». Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:f6c11e50-c059-4254-9dfc-5cbd2ee8147f.

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In order for computers to interact with and understand the visual world, they must be equipped with reasoning systems that include high–level quantities such as objects, actions, and scenes. This thesis is concerned with extracting such representations of the world from visual input. The first part of this thesis describes an approach to scene understanding in which texture characteristics of the visual world are used to infer scene categories. We show that in the context of a moving camera, it is common to observe images containing very few individually salient image regions, yet overall texture structure often allows our system to derive powerful contextual cues about the environment. Our approach builds on ideas from texture recognition, and we show that our algorithm out–performs the well–known Gist descriptor on several classification tasks. In the second part of this thesis we we are interested in scene understanding in the context of multiple calibrated views of a scene, as might be obtained from a Structure–from–Motion or Simultaneous Localization and Mapping (SLAM) system. Though such systems are capable of localizing the camera robustly and efficiently, the maps produced are typically sparse point-clouds that are difficult to interpret and of little use for higher–level reasoning tasks such as scene understanding or human-machine interaction. In this thesis we begin to address this deficiency, presenting progress towards modeling scenes using semantically meaningful primitives such as floor, wall, and ceiling planes. To this end we adopt the indoor Manhattan representation, which was recently proposed for single–view reconstruction. This thesis presents the first in–depth description and analysis of this model in the literature. We describe a probabilistic model relating photometric features, stereo photo–consistencies, and 3D point clouds to Manhattan scene structure in a Bayesian framework. We then present a fast dynamic programming algorithm that solves exact MAP inference in this model in time linear in image size. We show detailed comparisons with the state–of–the art in both the single– and multiple–view contexts. Finally, we present a framework for learning within the indoor Manhattan hypothesis class. Our system is capable of extrapolating from labelled training examples to predict scene structure for unseen images. We cast learning as a structured prediction problem and show how to optimize with respect to two realistic loss functions. We present experiments in which we learn to recover scene structure from both single and multiple views — from the perspective of our learning algorithm these problems differ only by a change of feature space. This work constitutes one of the most complicated output spaces (in terms of internal constraints) yet considered within a structure prediction framework.

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Vallee, Emmanuel. « Improving sensitivity and specificity in diffusion MRI group studies ». Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:11b235ef-c05f-4db3-a8fb-291ab07d4f84.

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Diffusion MRI provides a unique opportunity to study the brain tissue architecture at a microscopic level. More specifically, it allows to infer biophysical properties of the axons in the white matter in-vivo. Microstructural parameters are widely used in multi-subject studies to track pathological processes, follow normal development and aging, or investigate behaviour. This thesis aims to identify and potentially address the limitations and pitfalls in voxelwise comparison of diffusion MRI parameters across subjects. To allow for accurate matching of brain structures across subjects, non-linear transformation that spatially aligns the data is required. We demonstrate that using advanced registration methods, we can outperform the standard registration-projection approach both in terms of sensitivity and specificity. The coarse resolution of the data typically causes partial volume effects that bias the diffusion parameters and potentially mislead the interpretation of a group study outcome. We provide evidence that these effects can be addressed by constraining the diffusion model parameter space, which leads to marginally lower sensitivity, but allows an accurate interpretation of the results. Additionally, we suggest that additional information inferred with a data driven approach might mitigate the loss in sensitivity. Finally, we design an original tract-specific modelling framework that enables to estimate microstructural parameters unbiased by the presence of foreign fibre populations or tissues. We demonstrate the sensitivity of our method in a study relating microstructure and behaviour.

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Marshall, Cicely. « Endemism hotspots and floristics of Upper Guinea in the context of tropical Africa ». Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:73457f5c-c057-4083-80b2-d361b9be3305.

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This thesis documents patterns in plant species distribution across tropical Africa. Geographic patterns in the distribution of globally rare plants within Upper Guinea are emphasised, and correlates with these patterns are investigated. This thesis argues that globally rare species can and should be emphasised in conservation strategy. Approximately 3.7 million global occurrence records of 28,803 tropical mainland African vascular plant species are compiled into a database framework. The database is used to propose an updated biogeographic framework for tropical Africa, which is sympathetic to previous chorological frameworks but maximises regional endemism within quantitatively defined boundaries. A definition of Upper Guinea as the forests of West Africa between Sierra Leone and Ghana is recovered. The concentration of globally rare species in the tropical African flora (bioquality as measured by the GHI) is calculated and mapped at one degree square and half degree square resolution, revealing high bioquality of the horn of Africa. Bioquality is calculated by categorising the global area of occupancy of all tropical African taxa into a Star rating, with the result that a bioquality score can now be calculated at a local scale anywhere in tropical Africa to inform conservation strategy. At the local scale, variation in bioquality is modelled in two areas of high global endemism within Upper Guinea: the Nimba Mountains and SW Ghana. Disturbance is the only significant variable retained in both models, and shows a strong negative relationship with bioquality. Bioquality scores in forest reserves of SW Ghana are shown to have been stable over 20 years, although our perception of the global rarity and identity of species within the area has altered substantially. This finding supports the GHI as a metric of conservation priority in the face of partial information. At half degree square resolution, 55% of tropical African cells are estimated to have less than 2.5% of their likely species richness documented. A regression tree model is used to interpolate bioquality scores for cells lacking species distribution data, making use of a range of modern climatic, paleo climatic, geographic and biogeographic variables, found to be predictive of bioquality scores. Areas showing the most stable climates over the past 21,000 years are shown to have the highest modern-day bioquality across tropical Africa. Areas with relatively stable climates during periods of past climate change have been hypothesised to show high modern endemism as the result of increased speciation in isolated refugia, and/or a lower rate of extinction within the refugia. Two dated phylogenies are estimated for African magnoliids and Rubiaceae species, which show that most of Upper Guinea's globally rare species are young, vicariant species, although at least one species is likely to be a paleo-endemic, supporting both hypotheses. Areas with historically stable climates showing present day climatic or topological isolation explain areas of high global endemism in tropical Africa, although the introduction of a high disturbance regime can remove this pattern. A conservation strategy which promotes the protection of globally rare species in tropical Africa is feasible, given what we now know of the African flora, and is wise, at least given the success of the Ghanaian programme over 20 years.

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Kilshaw, Kerry A. « Introgression and the current status of the Scottish wildcat (Felis silvestris silvestris) ». Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:11c27f05-c051-4cbb-b498-538561005d87.

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Baseline data on a species' distribution and abundance are essential for developing practical conservation management plans. Such data are difficult to obtain for many low density cryptic carnivores. The Scottish wildcat, Felis silvestris silvestris, is no exception with <400 individuals thought to remain. Its conservation has been further complicated by extensive hybridisation and introgression with the domestic cat (F.s.catus). Hybridisation has also resulted in difficulties in discriminating between wildcats, wildcat x domestic hybrids (hybrids) and tabby coloured feral domestic cats. This has inhibited survey efforts, leading to a lack of general ecological information. Using the most recent identification tools available, extensive surveys using various methods including camera trapping were carried out across Northern Scotland in order to examine the current status of the Scottish wildcat. Current distribution indicates a more restricted range than recent studies. Wildcats are at risk of hybridisation from feral domestic cats and in particular, hybrids, throughout their current probable range. The distribution of hybrids overlaps with both feral domestic cats and wildcats, pointing to a significant threat from hybrids acting as a bridge between wildcats and feral cats. Mean density estimates of 3.5 (SD=0.7) wildcats/100 km² were comparable with those from other studies in Scotland using different survey methods. Total population size estimates ranged between 115-314 individuals depending on local densities and home range size. Population viability analysis (PVA) indicated the current population is not viable unless management actions are undertaken in the near future (Mean time to extinction = 48.2 years (SD = 9.39), probability of extinction=1, SE = 0), and that reducing mortality rates and/or supplementing populations from captive bred cats are likely to be necessary to achieve viability. Based on these data, the Scottish wildcat may be more endangered than many other species classified as Endangered and the current status of the Scottish wildcat should be reviewed.

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Livres sur le sujet "C05X"

(Firm), BPP Learning Media. CIMA Certificate paper C05 : Fundamentals of ethics, corporate governance and business law : Practice & revision kit. London : BPP Learning Media, 2012.

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Bollman, Wease. A biological assessment of sites in the Bitterroot River Drainage, Ravalli County, Montana : Project TMDL-C05, October 2002. Missoula, Montana : Rhithron Associates, 2003.

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Publishing, Kaplan. CIMA C05 Bitesize (Cima). Kaplan Publishing Foulks Lynch, 2006.

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Publishing, Kaplan. Cima Paper C05 Assessment Kit (Cima). Kaplan Publishing Foulks Lynch, 2006.

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Whimsical Worlds : Grades K-3 (Accelerated Reader Reading Practice Quizzes C05). Renaissance Learning Inc, 2000.

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Fundamentals of Ethics, Corporate Governance and Business Law - Study Text : Paper C05. Kaplan Publishing, 2009.

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Timmins, Nicholas. The most expensive breakfast in history : revisiting the Wanless review 20 years on. The Health Foundation, 2021. http://dx.doi.org/10.37829/hf-2021-c05.

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Chapitres de livres sur le sujet "C05X"

Rousseau, Jean-Jacques. « Le Devin du village ». Dans Recent Researches in the Music of the Classical Era, 50. A-R Editions, 1998. http://dx.doi.org/10.31022/c050.

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Brioschi, Antonio. « Six Symphonies ». Dans Recent Researches in the Music of the Classical Era, 51. A-R Editions, 1998. http://dx.doi.org/10.31022/c051.

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« Ballet Music from the Mannheim Court, Part 3 ». Dans Recent Researches in the Music of the Classical Era, 52. A-R Editions, 1998. http://dx.doi.org/10.31022/c052.

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« Four Viennese String Quintets ». Dans Recent Researches in the Music of the Classical Era, 53. A-R Editions, 1998. http://dx.doi.org/10.31022/c053.

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Gaviniés, Pierre. « Six Sonatas for Two Violins, Opus 5 ». Dans Recent Researches in the Music of the Classical Era, 54. A-R Editions, 1999. http://dx.doi.org/10.31022/c054.

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Ritter, Georg Wenzel. « Six Quartets for Bassoon and Strings, Opus 1 ». Dans Recent Researches in the Music of the Classical Era, 55. A-R Editions, 1999. http://dx.doi.org/10.31022/c055.

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Asplmayr, Franz. « Six Quatuors Concertantes, Opus 2 ». Dans Recent Researches in the Music of the Classical Era, 56. A-R Editions, 1999. http://dx.doi.org/10.31022/c056.

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« Ballet Music from the Mannheim Court, Part 4 ». Dans Recent Researches in the Music of the Classical Era, 57. A-R Editions, 1999. http://dx.doi.org/10.31022/c057.

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Linley, Thomas. « The Song of Moses ». Dans Recent Researches in the Music of the Classical Era, 58. A-R Editions, 2000. http://dx.doi.org/10.31022/c058.

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Ozi, Etienne. « Six duos pour deux bassons ». Dans Recent Researches in the Music of the Classical Era, 59. A-R Editions, 2000. http://dx.doi.org/10.31022/c059.

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Actes de conférences sur le sujet "C05X"

Matsuno, Rayna K., Ben Porter, Steven Warner, Deborah B. Bookwalter et Natalie Wells. « Abstract C055 : Human papillomavirus vaccination among US military service women ». Dans Abstracts : Eleventh AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved ; November 2-5, 2018 ; New Orleans, LA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7755.disp18-c055.

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Hood, Robert B., et Ashley Felix. « Abstract C057 : Neighborhood disadvantage is associated with liver cancer treatment and survival ». Dans Abstracts : Twelfth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved ; September 20-23, 2019 ; San Francisco, CA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7755.disp19-c057.

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Gauthier, Kelsey E. Sivick, Kenneth V. Lawson, Dana Piovesan, Matthew J. Walters, Ada Chen, Xiaoning Zhao, Cesar Meleza et al. « Abstract C050 : A novel, potent, and selective hypoxia-inducible factor (HIF)-2α antagonist ». Dans Abstracts : AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics ; October 26-30, 2019 ; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-c050.

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Mladek, Ann C., Shiv Gupta, Minjee Kim, Afroz Shareef Mohammad, Katrina K. Bakken, Helen He, Zeng Hu et al. « Abstract C051 : MDM2 inhibitor KRT-232 extends survival in glioblastoma patient-derived xenograft models ». Dans Abstracts : AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics ; October 26-30, 2019 ; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-c051.

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Lewis, Deyana D., Shukmei Wong, Angela S. Baker, Joan E. Bailey-Wilson, John D. Carpten et Cheryl D. Cropp. « Abstract C050 : Deleterious coding variants in African American Hereditary Prostate Cancer Study (AAHPC) families ». Dans Abstracts : Eleventh AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved ; November 2-5, 2018 ; New Orleans, LA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7755.disp18-c050.

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Gonzalez-Pons, Maria, Carlos Torres-Cintrón, Marievelisse Soto-Salgado, Douglas Morgan et Marcia Cruz-Correa. « Abstract C054 : Gastric cancer survival among Puerto Rican Hispanics : A ten-year population-based analysis ». Dans Abstracts : Eleventh AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved ; November 2-5, 2018 ; New Orleans, LA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7755.disp18-c054.

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Picado, Omar, Jordan Baeker-Bispo, Layla Bouzoubaa, Raymond R. Balise, Gilberto Lopes et Erin N. Kobetz. « Abstract C056 : Cancer patterns and trends in Costa Rica : A population-based tumor registry study ». Dans Abstracts : Eleventh AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved ; November 2-5, 2018 ; New Orleans, LA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7755.disp18-c056.

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Cheng, Iona, Juan Yang, Chiuchen Tseng, Jun Wu, Shannon M. Conroy, Salma Shariff-Marco, Scarlett Lin Gomez et al. « Abstract C050 : Association between outdoor air pollution and breast cancer survival : The Multiethnic Cohort Study ». Dans Abstracts : Twelfth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved ; September 20-23, 2019 ; San Francisco, CA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7755.disp19-c050.

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MARINHO, Claudia Teixeira, Bruno NASCIMENTO, Ana VIDELA et Flávia SOARES. « Design da Terra : reflexões sobre projeto de país ». Dans 14º Congresso Brasileiro de Pesquisa e Desenvolvimento em Design. São Paulo : Editora Blucher, 2022. http://dx.doi.org/10.5151/ped2022-c05.

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Ronca, Roberto, Gaia Cristina Ghedini, Federica Maccarinelli, Antonio Sacco, Silvia Laura Locatelli, Eleonora Foglio, Sara Taranto et al. « Abstract C052 : FGF trapping impairs multiple myeloma growth through c-Myc degradation-induced mitochondrial oxidative stress ». Dans Abstracts : AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics ; October 26-30, 2019 ; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-c052.

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Rapports d'organisations sur le sujet "C05X"

Reichenberger, Michael, et Jagoda Urban-Klaehn. Measurement results for 60Co Assay baskets H5, H9, H14, H15, A4, and B3 (C003, C001, C005, C022, C021, C020, C032, C033, C038, C035, C036, C039, C053, C054, C055, C065, C066, & ; C067). Office of Scientific and Technical Information (OSTI), août 2020. http://dx.doi.org/10.2172/1668826.

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