Thèses sur le sujet « Biochemical Investigations »
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Patel, Vinood Bhagwandas. « Biochemical investigations into experimental alcoholic cardiomyopathy and hypertension ». Thesis, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266477.
Texte intégralTaylor, Claire Louise. « Biochemical investigations of defects of the mitochondrial respiratory chain ». Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.281706.
Texte intégralShnoudeh, Abeer Jabra. « Biochemical and biophysical investigations of novel phosphodiesterase-5 inhibitors ». Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429578.
Texte intégralHarrison, Peter J. « Biochemical investigations of the carotenoid cleavage dioxygenase enzyme family ». Thesis, University of Warwick, 2014. http://wrap.warwick.ac.uk/66554/.
Texte intégralHaggarty-Weir, Christopher Neil. « Biochemical and biophysical investigations into key malaria parasite proteins ». Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/29617.
Texte intégralBerrisford, John Mark. « Biochemical and structural investigations on phosphoglucose isomerase from Pyrococcus furiosus ». Thesis, University of Sheffield, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434961.
Texte intégralKonrad, Josef. « In vitro culture of Babesia divergens : biochemical and immunological investigations ». Thesis, Imperial College London, 1986. http://hdl.handle.net/10044/1/38073.
Texte intégralLee, Jenny Swee Chin. « Biochemical and physiological investigations of Brassica oleracea var. botrytis L ». Thesis, University of Bath, 1985. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355378.
Texte intégralCoates, Christopher J. « Hemocyanin-derived phenoloxidase : biochemical and cellular investigations of innate immunity ». Thesis, University of Stirling, 2012. http://hdl.handle.net/1893/12228.
Texte intégralTormey, William Patrick. « The provision of biochemical investigations in forensic toxicology for coroners ». Thesis, Ulster University, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.646399.
Texte intégralHuggins, Anthony. « Investigations into the role of endogenous Annexin-A1 in dendritic cell biology ». Thesis, Queen Mary, University of London, 2012. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8302.
Texte intégralAldosary, Mazhor Salem K. « Biochemical and molecular genetic investigations of patients with mitochondrial DNA disease ». Thesis, University of Newcastle Upon Tyne, 2011. http://hdl.handle.net/10443/1121.
Texte intégralZainuddin, Siti Lailatul Akmar. « Immunohistochemical and biochemical investigations into the spatial distribution of amelogenin isoforms ». Thesis, University of Leeds, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522918.
Texte intégralHansen, R. K. « Biophysical and biochemical investigations of the M2 peptide of influenza A ». Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603662.
Texte intégralKoudouna, Elena. « Structural and biochemical investigations of the cornea and the trabecular meshwork ». Thesis, Cardiff University, 2013. http://orca.cf.ac.uk/56775/.
Texte intégralImtiaz, Faiqa. « Biochemical and genetic investigations on patients with congenital disorders of glycosylation ». Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269733.
Texte intégralChang, Michelle M. (Michelle Miran). « Biochemical and biophysical investigations of N-linked glycosylation pathways in archaea ». Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/97981.
Texte intégralCataloged from PDF version of thesis. "December 2014."
Includes bibliographical references.
Asparagine-linked glycosylation is an abundant and complex protein modification conserved among all three domains of life. Much is known about N-glycan assembly in eukaryotes and selected bacteria, in which the oligosaccharyltransferase (OTase) carries out the en bloc transfer of glycans from polyprenyl-PP-linked donors onto asparagine side chains of acceptor proteins. The first aim of this thesis is to elucidate the biochemical details of archaeal N-linked glycosylation, specifically through in vitro analysis of the polyprenyl-P-dependent pathway of the methanogenic archaeon Methanococcus voltae. The archaeal OTase, known as AglB, utilizes a-linked dolichyl-P-trisaccharide substrate as the glycosyl donor for transfer to the acceptor protein. This dolichyl-P-glycan is generated by an initial retaining glycosyltransferase (AglK) and elaborated by additional glycosyltransferases (AglC and AgIA) to afford Dol-P-GlcNAc- Glc-2,3-diNAcA-ManNAc(6Thr)A. Despite the homology to other bacterial or eukaryotic OTases that exploit polyprenyl-PP-linked substrates, the M. voltae AglB efficiently transfers disaccharide to model peptides from the Dol-P-GlcNAc-Glc-2,3-diNAcA monophosphate. While this archaeal pathway affords the same asparagine-linked P-glycosyl amide products generated in bacteria and eukaryotes, these studies provide the first biochemical evidence revealing that despite the apparent similarities of the overall pathways, there are actually two general strategies to achieve N-linked glycoproteins across the domains of life. A second focus of this thesis involves biophysical studies to probe structural features and conformational dynamics of AglB. An intramolecular LRET experimental system was developed to report on substrate binding and the resulting structural transformations in AgIB. There is a strong need for detailed studies on the mechanistic and functional significance of archaeal adaptations of N-linked glycosylation, especially exploring differences between AglB and other OTases that allow AglB to utilize these unique polyprenyl-P-linked substrates. Lastly, a cell-free expression system was established for the efficient synthesis of Alg5, a yeast dolichyl-phosphate glucosyltransferase that shares high sequence similarity to AglK, the first glycosyltransferase in the M. voltae pathway. Dol-P-Glc was generated and examined to unambiguously characterize the stereochemistry of the product of Alg5.
by Michelle M. Chang.
Ph. D.
Krämer, Franziska. « Molecular and biochemical investigations into VMD2, the gene associated with Best disease ». [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968349293.
Texte intégral[Verfasser], Fahrurrozi, et Bernward [Akademischer Betreuer] Bisping. « Microbiological and biochemical investigations of cocoa bean fermentation / Fahrurrozi. Betreuer : Bernward Bisping ». Hamburg : Staats- und Universitätsbibliothek Hamburg, 2015. http://d-nb.info/1072713268/34.
Texte intégralSacho, Elizabeth J. Erie Dorothy A. « Biophysical and biochemical investigations of proteins involved in genomic maintenance and stability ». Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1431.
Texte intégralTitle from electronic title page (viewed Apr. 25, 2008). " ... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry." Discipline: Chemistry; Department/School: Chemistry.
Xu, Hui. « Molecular biological and biochemical investigations of the biosynthesis of the aminocoumarin antibiotics ». [S.l. : s.n.], 2004. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB11195194.
Texte intégralFan, Aili [Verfasser], et Shu-Ming [Akademischer Betreuer] Li. « Biochemical investigations on bacterial and fungal prenyltransferases / Aili Fan. Betreuer : Shu-Ming Li ». Marburg : Philipps-Universität Marburg, 2016. http://d-nb.info/1082379085/34.
Texte intégralCollins, Jane E. « Biochemical and physiological investigations of volatile oil production in Monarda citriodora var. citriodora ». Thesis, Liverpool John Moores University, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337898.
Texte intégralSlivka, Eric John. « Structural and biochemical investigations of the thyroid hormone receptor and v-erbA oncoprotein ». Diss., Search in ProQuest Dissertations & ; Theses. UC Only, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3352469.
Texte intégralKar, Rekha. « Investigations of the mechanisms of cell death induced by 15-deoxy delta (12,14) prostaglandin J2 a dissertation / ». San Antonio : UTHSC, 2008. http://proquest.umi.com.libproxy.uthscsa.edu/pqdweb?did=1663069051&sid=2&Fmt=2&clientId=70986&RQT=309&VName=PQD.
Texte intégralWinkelblech, Julia [Verfasser], et Shu-Ming [Akademischer Betreuer] Li. « Biochemical investigations on bacterial and fungal dimethylallyltryptophan synthases / Julia Winkelblech ; Betreuer : Shu-Ming Li ». Marburg : Philipps-Universität Marburg, 2016. http://d-nb.info/1120583756/34.
Texte intégralBonitz, Tobias [Verfasser], et Lutz [Akademischer Betreuer] Heide. « Biochemical Investigations of Aromatic Prenyltransferases from the ABBA Superfamily / Tobias Bonitz ; Betreuer : Lutz Heide ». Tübingen : Universitätsbibliothek Tübingen, 2013. http://d-nb.info/1162844345/34.
Texte intégralMohabir, G. « Biochemical investigations of yield-limitations in potatoes (Solanum tuberosum L.) under warm tropical conditions ». Thesis, University of Reading, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380838.
Texte intégralGray, Julie Anne. « Investigations into the use of the biochemical markers of bone metabolism in the horse ». Thesis, Open University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336810.
Texte intégralChan, Susan L. F. « Biochemical and pharmacological investigations into the role of α2-adrenoceptors in rat islets of Langerhans ». Thesis, Keele University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292754.
Texte intégralDavis, Aubrey K. « Biochemical, molecular, and genomic investigations into the response of the diatom Thalassiosira pseudonana to copper stress / ». Diss., Connect to a 24 p. preview or request complete full text in PDF formate. Access restricted to UC campuses, 2005. http://wwwlib.umi.com/cr/ucsd/fullcit?p3191991.
Texte intégralPonnusamy, Rajesh [Verfasser]. « Crystallographic and biochemical investigations on coronarvirus replication proteins - non-structural proteins 8 and 9 / Rajesh Ponnusamy ». Lübeck : Zentrale Hochschulbibliothek Lübeck, 2010. http://d-nb.info/1004773706/34.
Texte intégralKunze, Kurt, Hendrik Niemann, Susanne Ueberlein, Renate Schulze, Hermann Ehrlich, Eike Brunner, Peter Proksch et Karl-Heinz van Pée. « Brominated Skeletal Components of the Marine Demosponges, Aplysina cavernicola and Ianthella basta : Analytical and Biochemical Investigations ». Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-127045.
Texte intégralPhilpott, Amelia. « Investigations into the biochemical and cellular biology of a cytoplasmic dynein mutation, abnormal rear leg (Arl) ». Thesis, University of Sussex, 2011. http://sro.sussex.ac.uk/id/eprint/6977/.
Texte intégralWarburton, Sarah. « Biochemical Investigations of Macular Degeneration : The Significance of Protein Oxidation including Novel Methods for Its Study ». Diss., CLICK HERE for online access, 2006. http://contentdm.lib.byu.edu/ETD/image/etd1583.pdf.
Texte intégralPockrandt, Daniel [Verfasser], et Shu-Ming [Akademischer Betreuer] Li. « Molecular biological and biochemical investigations of prenyltransferases from different Aspergillus species / Daniel Pockrandt. Betreuer : Shu-Ming Li ». Marburg : Philipps-Universität Marburg, 2014. http://d-nb.info/1052994768/34.
Texte intégralDuz, Marco. « Biochemical and epidemiological investigations of non-steroidal anti-inflammatory drug usage and related side effects in equids ». Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7581/.
Texte intégralMaratos, Eleni Chryssa. « Behavioural and biochemical investigations into dyskinesia by levodopa or dopamine agonists in the MPTP-treated common marmoset ». Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271323.
Texte intégralLiebhold, Mike Patrick [Verfasser], et Shu-Ming [Akademischer Betreuer] Li. « Biochemical Investigations on Microbial Prenyltransferases in the Presence of DMAPP Analogues / Mike Patrick Liebhold. Betreuer : Shu-Ming Li ». Marburg : Philipps-Universität Marburg, 2015. http://d-nb.info/1071947915/34.
Texte intégralLange, Christiane [Verfasser], et Dieter [Akademischer Betreuer] Jahn. « Structural and biochemical investigations of the late enzymes of (bacterio)chlorophyll a biosynthesis / Christiane Lange ; Betreuer : Dieter Jahn ». Braunschweig : Technische Universität Braunschweig, 2016. http://d-nb.info/1175818798/34.
Texte intégralChahyadi, Agus [Verfasser], et Maike [Akademischer Betreuer] Petersen. « Biochemical and Molecular Investigations of Arabidopsis thaliana Transformed with Genes of Rosmarinic Acid Biosynthesis / Agus Chahyadi ; Betreuer : Maike Petersen ». Marburg : Philipps-Universität Marburg, 2017. http://d-nb.info/1136718508/34.
Texte intégralGuymer, David. « Biochemical and physiological investigations of the activities of TorD family chaperones in Escherichia coli and Salmonella enterica serovar Typhimurium ». Thesis, University of Dundee, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505653.
Texte intégralSingh, Poonam Verfasser], Ludger [Akademischer Betreuer] Beerhues et Robert [Akademischer Betreuer] [Hänsch. « Biochemical and molecular investigations of benzoic acid metabolism in Hypericum calycinum cell cultures / Poonam Singh ; Ludger Beerhues, Robert Hänsch ». Braunschweig : Technische Universität Braunschweig, 2020. http://d-nb.info/1203798792/34.
Texte intégralSequeira, Suzanne Simone. « '1 NMR spectroscopic investigations into the metabolism and biochemical effects of model drugs and enzyme inducers in the rat ». Thesis, Birkbeck (University of London), 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342211.
Texte intégralWanaguru, Madushi Kaushla. « Biochemical investigations of Plasmodium falciparum erythrocyte invasion pathways using recombinant merozoite surface proteins produced in a mammalian expression system ». Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607835.
Texte intégralGiannetti, Anthony Michael Rees Douglas C. « Biochemical, biophysical, and cellular investigations of the interactions of transferrin receptor with transferrin and the hereditary hemochromatosis protein, HFE / ». Diss., Pasadena, Calif. : California Institute of Technology, 2004. http://resolver.caltech.edu/CaltechETD:etd-05262004-173612.
Texte intégralPeng, Chen. « Synthesis of very-long-chain bifunctional and isotope-labeled compounds for biochemical investigations into novel compounds in plant cuticular waxes ». Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43752.
Texte intégralMikołajka, Aleksandra. « Functional and structural studies of the FGFR1 oncogene partner protein and biochemical investigations of the retinoblastoma protein and its binding partners ». [S.l.] : [s.n.], 2007. http://mediatum2.ub.tum.de/doc/614708/document.pdf.
Texte intégralYu, Xia [Verfasser], et Shu-Ming [Akademischer Betreuer] Li. « Molecular biological and biochemical investigations on the biosynthetic enzymes of prenylated indole alkaloids from fungi / Xia Yu. Betreuer : Shu-Ming Li ». Marburg : Philipps-Universität Marburg, 2013. http://d-nb.info/1038786347/34.
Texte intégralSeifert, Florian Ulrich [Verfasser], et Heinrich [Akademischer Betreuer] Leonhardt. « Structural and biochemical investigations of the eukaryotic DNA double-strand break repair complex Mre11-Rad50-Nbs1 / Florian Ulrich Seifert ; Betreuer : Heinrich Leonhardt ». München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/111907388X/34.
Texte intégral