Bibliographies thématiques / Bigyan

Littérature scientifique sur le sujet « Bigyan »

Auteur : Grafiati
Publié le 18 mai 2024

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Articles de revues sur le sujet "Bigyan"

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Chhetri, Jyoti, Krishna Gurung, Abhisek Khadka, Reeju Sharma, Mira Kumari Khatri, Anil Bhujel, Amrita Acharaya et Goma Pokharel. « Synergistic Effects of Artemisia vulgaris, Ocimum tenuiflorum, Azadirachta indica and Castanopsis indica Extracts against Methicillin-Resistant Staphylococcus aureus ». Himalayan Biodiversity 5, no 1 (28 décembre 2017) : 38–44. http://dx.doi.org/10.3126/hebids.v5i1.36152.

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Staphylococcus aureus is a major public health concern. Methicillin resistant Staphylococcus aureus is not only resistant to methicillin and other β-lactam antibacterial agents but also to other antibacterial agents. Therefore, new agents are needed to treat Methicillin Resistant Staphylococcus aureus (MRSA). The main aim of the present research was to study the antibacterial activity of four plants extract against clinical isolates of Staphylococcus aureus at the purpose of overcoming its infection. The current investigation was carried out at Pokhara Bigyan tatha Prabidhi Campus based on the evaluation of traditional plants on its antibacterial activity against MRSA. Antibacterial activity of the medicinal plant extract was observed by mixing 100 g powder of collected leaves in 70% methanol making 1000 sml. After performed processes, extract was filtered and methanol was evaporated. Antibacterial activity of the medicinal plant extract was determined using agar well diffusion assay method. Methanol leaf extracts may have the potential to act against MRSA and could be a possible source to obtain new and effective herbal medicines to treat infections caused by methicillin resistant strains of microorganisms from community as well as hospital settings. The synergistic effect was clearly observed among all four medicinal herbs.
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Bhattarai, Shreya, et Rakesh Kusma. « Preparation And Quality Evaluation Of Sugar And Honey Based Beetroot Candies ». Sustainability in Food and Agriculture 3, no 1 (2022) : 15–18. http://dx.doi.org/10.26480/sfna.01.2022.15.18.

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Beetroot is notable for its sweetness, high sugar content, but is very low in calories. Despite its nutritional value, many people refuse to consume it because of its earthy flavor. So, the study was conducted in the laboratory of Pokhara Bigyan Tatha Prabidhi Campus from September 2020 to December 2020 to prepare sugar and honey-based beetroot candy and make a comparative study on their qualities. By following the preliminary operations, fresh beetroot was candied by using honey and sugar syrup of 30 °Brix. Within certain days of boiling and draining of syrup, a gradual increment of TSS was obtained up to 70 °Brix and was finally dried at 55±3 ℃. The moisture content (26.18±0.58), crude fat (0.52±0.01), crude protein (1.60±0.14), crude fiber (2.39±0.19), titratable acidity (0.23±0.05), pH (5.82±0.02), reducing sugar (38.07±0.28), color (6.7±0.24), flavor (6.3±0.18), texture (6.65±0.25), taste (7.10±0.22), appearance (7.17±0.27) and overall acceptability (7.10±0.24) was recorded more in honey-based candy while carbohydrate (70.01±0.76) and ash (1.75±0.13) was recorded more in sugar-based candy. The total soluble solid was obtained equally in both sugar and honey-based candy which was 70 °Brix. The honey-based candy was better in nutritional, chemical and sensory attributes so it is suggested to use honey as a syrup instead of sugar syrup.
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Schuman, Joel S. « Biglan Festschrift ». Seminars in Ophthalmology 23, no 5-6 (janvier 2008) : 335. http://dx.doi.org/10.1080/08820530802505880.

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Stoecker, Judith L. « The Biglan classification revisited ». Research in Higher Education 34, no 4 (août 1993) : 451–64. http://dx.doi.org/10.1007/bf00991854.

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SANTOS COSTA, VÍTOR, et DAVID VAZ. « BigYAP : Exo-compilation meets UDI ». Theory and Practice of Logic Programming 13, no 4-5 (juillet 2013) : 799–813. http://dx.doi.org/10.1017/s1471068413000501.

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AbstractThe widespread availability of large data-sets poses both an opportunity and a challenge to logic programming. A first approach is to couple a relational database with logic programming, say, a Prolog system with MySQL. While this approach does pay off in cases where the data cannot reside in main memory, it is known to introduce substantial overheads. Ideally, we would like the Prolog system to deal with large data-sets in an efficient way both in terms of memory and of processing time. Just In Time Indexing (JITI) was mainly motivated by this challenge, and can work quite well in many application.Exo-compilation, designed to deal with large tables, is a next step that achieves very interesting results, reducing the memory footprint over two thirds. We show that combining exo-compilation with Just In Time Indexing can have significant advantages both in terms of memory usage and in terms of execution time.An alternative path that is relevant for many applications is User-Defined Indexing (UDI). This allows the use of specialized indexing for specific applications, say the spatial indexing crucial to any spatial system. The UDI sees indexing as pluggable modules, and can naturally be combined with Exo-compilation. We do so by using UDI with exo-data, and incorporating ideas from the UDI into high-performance indexers for specific tasks.
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Cai, Lingtao. « Comparative Analysis the Super-Resolution Image Generation Performance Based on BigGAN and VQ-VAE-2 ». Highlights in Science, Engineering and Technology 41 (30 mars 2023) : 202–10. http://dx.doi.org/10.54097/hset.v41i.6812.

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Super-resolution image reconstruction has always been a popular research direction in the field of computer vision, which aims to recover high-resolution clear images from low-resolution images. Traditional super-resolution reconstruction algorithms mainly rely on the construction of constraints and the accuracy of registration between images to achieve the reconstruction effect, but their accuracy cannot meet the needs of practical applications with large multiples. Thanks to the rapid development of deep learning field, super-resolution image reconstruction based on deep learning has become the mainstream, and has achieved great success in reconstruction accuracy and speed. According to the different generative models used, the existing super-resolution image reconstruction methods mainly include two categories: GAN-based and VAEs-based. To quantitatively compare the limits of the two approaches' performance, this study selects two representative algorithms, BigGAN and VQ-VAE-2, and introduces the theoretical details and training process of these two methods, respectively. Furthermore, the reconstruction results of BigGAN and VQ-VAE-2 are further compared. Finally, this paper discusses the future development trend of super-resolution picture reconstruction with the current potential problems of BigGAN and VQ-VAE-2.
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Hoermann, Henrike, Irena Krueger, Nadine Maurus, Friedrich Reusswig, Yi Sun, Christina Kohlmorgen, Maria Grandoch, Jens W. Fischer et Margitta Elvers. « The Proteoglycan Biglycan Modulates Platelet Adhesion and Thrombus Formation in a GPVI-Dependent Manner ». International Journal of Molecular Sciences 22, no 22 (10 novembre 2021) : 12168. http://dx.doi.org/10.3390/ijms222212168.

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Background: Vascular injury induces the exposure of subendothelial extracellular matrix (ECM) important to serve as substrate for platelets to adhere to the injured vessel wall to avoid massive blood loss. Different ECM proteins are known to initiate platelet adhesion and activation. In atherosclerotic mice, the small, leucine-rich proteoglycan biglycan is important for the regulation of thrombin activity via heparin cofactor II. However, nothing is known about the role of biglycan for hemostasis and thrombosis under nonatherosclerotic conditions. Methods: The role of biglycan for platelet adhesion and thrombus formation was investigated using a recombinant protein and biglycan knockout mice. Results: The present study identified biglycan as important ECM protein for the adhesion and activation of platelets, and the formation of three-dimensional thrombi under flow conditions. Platelet adhesion to immobilized biglycan induces the reorganization of the platelet cytoskeleton. Mechanistically, biglycan binds and activates the major collagen receptor glycoprotein (GP)VI, because reduced platelet adhesion to recombinant biglycan was observed when GPVI was blocked and enhanced tyrosine phosphorylation in a GPVI-dependent manner was observed when platelets were stimulated with biglycan. In vivo, the deficiency of biglycan resulted in reduced platelet adhesion to the injured carotid artery and prolonged bleeding times. Conclusions: Loss of biglycan in the vessel wall of mice but not in platelets led to reduced platelet adhesion at the injured carotid artery and prolonged bleeding times, suggesting a crucial role for biglycan as ECM protein that binds and activates platelets via GPVI upon vessel injury.
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Wang, Bin, Guang-Xin Li, Shu-Guang Zhang, Quan Wang, Yu-Gang Wen, Hua-Mei Tang, Chong-Zhi Zhou et al. « Biglycan expression correlates with aggressiveness and poor prognosis of gastric cancer ». Experimental Biology and Medicine 236, no 11 (novembre 2011) : 1247–53. http://dx.doi.org/10.1258/ebm.2011.011124.

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Biglycan, a member of the small leucine-rich proteoglycan family, has been implicated in the development and progression of human cancers. However, the clinical significance of biglycan expression in gastric cancer has not been determined. In the present study, biglycan mRNA and protein concentrations were analyzed using quantitative realtime reverse transcription polymerase chain reaction and Western blot in 69 gastric cancer and adjacent non-tumorous tissues, respectively. Biglycan expression was further assessed using immunohistochemistry in tissue microarrays that contained 264 cases of gastric cancer, and others containing normal or metastasized lymph node tumor tissues. Biglycan was upregulated at the transcriptional and translational levels and there was a correlation between the expression of biglycan mRNA and protein ( P = 0.000, κ = 0.769). Over-expression of biglycan was strongly associated with lymph node metastasis, tumor (T) classification, metastasis (M) classification, vascular invasion and Union for International Cancer Control (UICC) stage. Patients with biglycan-positive tumors had a significantly higher disease recurrence rate and poorer survival than patients with biglycan-negative tumors after the radical surgery. Multivariate analysis revealed that biglycan expression is an independent prognostic indicator for survival of patients with gastric cancer. The data from the current study demonstrate that elevated expression of biglycan may play an important role in the development and progression of gastric cancer, and could be further evaluated as a biomarker for predication of a poor clinical outcome.
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Fairouz, Faiha, Rumana Rashid et Abdullah Abu Sayeed. « How Far Scientific is Snakebite Prevention and First Aid Treatment in School Textbook ? » Bangladesh Journal of Medicine 31, no 1 (30 décembre 2019) : 39–40. http://dx.doi.org/10.3329/bjm.v31i1.44753.

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Background: Snakebite is an old health problem in rural areas. In Bangladesh, the snakebite issue is included in school syllabus, in curriculum since long time, so that people can take/get immediate first aid treatment and can prevent snakebite. The success of snakebite treatment depends more on providing first aid treatment immediately after snakebite by learning and by sending the patients quickly to hospital. Snakebite is a preventable health problem indeed. If it can be prevented the rate of snakebite will also decrease. In the recently published snake bite management Guideline by WHO it has been targeted to reduce 50% of mortality & disability due to snakebite by 2030.1 Methods: a. The snakebite topic or issue has been thoroughly reviewed in the secondary and higher secondary school books. b. National Guidelines on snakebite in providing/ giving first aid treatment has been reviewed.2 c. The correlation between the topic to learn the subject and the national guidelines have been reviewed and given taken into account. d. The similarity or correlation between the national guidelines and the topic in the prevention of snakebite in the book have been observed & reviewed. It was a descriptive/narrative research study. Results: In the book of class IV in Primary and Secondary level students, ‘Elementary Science, (‘Prathomiik Bigghan’) page no. 86 and in book of class VIII Home Science (‘Gharjhastha Biggan’) page no. 16 the Snakebite issue/topic is mentioned.2,3 There are 22 information on the first aid/primary treatment of Snakebite among which 5 (five) are nonscientific rather harmful. (Table & Picture) Bangladesh J Medicine Jan 2020; 31(1) : 39-40
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Nastase, Madalina V., Marian F. Young et Liliana Schaefer. « Biglycan ». Journal of Histochemistry & ; Cytochemistry 60, no 12 (20 juillet 2012) : 963–75. http://dx.doi.org/10.1369/0022155412456380.

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Thèses sur le sujet "Bigyan"

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Johnson, Lisa Dawn. « Faculty Teaching Goals at Senior Research Universities ». Diss., Virginia Tech, 1997. http://hdl.handle.net/10919/30701.

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The purpose of this study was to identify faculty teaching goals at senior research universities and to determine variables which could be used to predict these goals. The eight disciplines used in this study were: accounting, chemistry, computer science, economics, English, math, mechanical engineering, and psychology. The independent variables were: gender, academic rank, course level, tenure, and four Biglan categories (pure-hard, pure-soft, applied-hard, and applied-soft). Using the Teaching Goals Inventory (Angelo & Cross, 1993), the teaching goals and primary teaching role of faculty at senior research universities across eight academic disciplines were identified (N = 352). Through a principal axis factor analysis, seven factors emerged for the data gathered from the Teaching Goals Inventory, results of which were slightly different from that of previous research. Further analyses indicated differences between the teaching goals and primary teaching role of faculty at senior research universities, community colleges, and four-year colleges. Seven one-way ANOVAs and subsequent post-hoc comparisons were conducted which indicated significant differences (p < .05) among the factor means across the eight academic disciplines. Comparisons of the primary teaching role across the eight academic disciplines also indicated significant differences (p < .05) in the percentage of faculty selecting each of the six roles. Furthermore, this study provides additional evidence to support the theory that the Biglan categories help explain the differences in teaching goals across academic disciplines. Significant differences (p < .05) were detected in the teaching goals and primary teaching role of senior research university faculty across the four Biglan categories. Through regression analyses, three of the four Biglan categories, gender, and level of course entered as predictors of teaching goals. Academic rank and tenure did not enter into any of the regression equations; however, further analyses indicated these variables were intercorrelated with several other independent variables. Implications for these findings are discussed.
Ph. D.
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Anciaux, Camille. « Édouard Bignon (1771-1841). Héraut de la gloire napoléonienne ». Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUL149.

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Ayant vécu de 1771 à 1841, Édouard Bignon incarne la génération d’hommes qui a traversé, non sans encombre, la Révolution, le Directoire, le Consulat, l’Empire, la Restauration et la monarchie de Juillet. Sa carrière est le reflet des changements politiques français. Précepteur à la fin de l’Ancien Régime, il s’enrôle dans l’armée en 1793 pour fuir les proscriptions de la Terreur. Sous le Directoire, en 1797, il intègre la carrière diplomatique au sein de laquelle il reste dix-neuf années, jusqu’en 1815 : il y connaît une progression continue, passant du rang de second secrétaire de légation en 1797 à celui de ministre plénipotentiaire en Pologne en 1813. Après avoir participé aux Cent-Jours, il se retire de la vie publique. Deux ans après Waterloo, il est élu député et siège dans les rangs de l’opposition libérale jusqu’à la chute de la monarchie bourbonienne. Indépendamment de ses mandats de députés, il se lance dans une carrière de publiciste et d’historien qui lui assure une notoriété grandissante. En effet, dans son testament, Napoléon Ier lui a commandé une histoire diplomatique de la France à laquelle Bignon s’attelle dès 1821. Divisée en quatorze tomes, cette Histoire de France paraît à partir de 1829. L’année suivante, Bignon participe à la chute de Charles X et devient proche des gouvernements de Louis-Philippe : il est nommé pair de France en 1837, couronnement d’une longue carrière au service de la France. Cette étude biographique, qui embrasse la totalité de sa carrière, entend mettre à l’honneur le parcours d’un diplomate napoléonien à l’envergure secondaire, les activités d’un parlementaire sous la Restauration et la monarchie Juillet, et l’originalité d’un historien de l’Empire
Born in 1771 and died in 1841, Édouard Bignon embodies the generation who has live, with some trouble, through the French Revolution, the Directory, the Consulate, the First Empire, the Restoration and the July Monarchy. His career reflects all the French political changes. A private tutor, he enlisted in 1793 while trying to avoid being arrested. During the Directory, in 1797, he joined the Foreign Office and stayed in this departement until 1815 : he was constantly promoted, from the position of 2nd secretary in 1797 to minister plenipotentiary in Poland in 1813. As he joined the ranks of Napoleon during The Hundred Days, he had to retire from public life once Louis XVIII came back. Two years after Waterloo, he became a member of Parliament and sat among the liberals until the Bourbons fall. Separately from his political activities, he published several historical books which rose his popularity. In his will, Napoleon asked him to write the diplomatic history of his reign. Begun in 1821, the Histoire de France was issued from 1829 to 1850 and split into 14 volumes. In 1830, he contributed to the July Monarchy’s birth and became one of its support in Parliament : Louis-Philippe rewarded him and appointed him as peer of France in 1837, as a public recognition for his duties. This study which tackles all Bignon’s activities, aims to emphasize a medium scale diplomatic experience, parliamentarian’s occupations during the Restoration and the July Monarchy and Napoleon historian’s originality
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Creely, Hilliary Elizabeth. « A role for biglycan in postsynaptic differentiation of the neuromuscular junction / ». View online version ; access limited to Brown University users, 2005. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3174592.

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Andrlová, Hana [Verfasser], et Robert [Akademischer Betreuer] Zeiser. « The role of biglycan in the tumor microenvironment of malignant melanoma ». Freiburg : Universität, 2017. http://d-nb.info/1138195308/34.

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Ramirez, Aviles Camila Alexandra. « P-bigon right-veeringness and overtwisted contact structures ». Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5609.

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A contact structure is a maximally non-integrable hyperplane field $\xi$ on an odd-dimensional manifold $M$. In $3$-dimensional contact geometry, there is a fundamental dichotomy, where a contact structure is either tight or overtwisted. Making use of Giroux's correspondence between contact structures and open books for $3$-dimensional manifolds, Honda, Kazez, and Mat\'{i}c proved that verifying whether a mapping class is right-veering or not gives a way of detecting tightness of the compatible contact structure. As a counter-part to right-veering mapping classes, right-veering closed braids have been studied by Baldwin and others. Ito and Kawamuro have shown how various results on open books can be translated to results on closed braids; introducing the notion of quasi right-veering closed braids to provide a sufficient condition which guarantees tightness. We use the related concept of $P$-bigon right-veeringness for closed braids to show that given a $3$-dimensional contact manifold $(M, \xi)$ supported by an open book $(S, \phi)$, if $L \subset (M, \xi)$ is a non-$P$-bigon right-veering transverse link in pure braid position with respect to $(S, \phi)$, performing $0$-surgery along $L$ produces an overtwisted contact manifold $(M', \xi')$. Furthermore, if we suppose $L \subset (M, \xi)$ is a pure and non-quasi right-veering braid with respect to $(S, \phi)$, performing $p$-surgery along $L$, for $p \geq 0$, gives rise to an open book $(S', \phi')$ which supports an overtwisted contact manifold $(M', \xi')$.
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Espinoza, Cuevas Beatriz Elsa, Asurza Erick Robinson Gamboa, Sanchez Viviana Noemi Virhuez et Quispe Ericka Luz Zuñiga. « Aplicación móvil para mototaxis BIGA ». Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2017. http://hdl.handle.net/10757/622229.

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Actualmente, se dan cerca de 26000 viajes en el distrito de San Juan de Lurigancho y eso sólo considerando a las cuatro asociaciones de mototaxis más grandes del distrito. Se sabe que existen más de quince y que cada una tiene, en promedio, entre 80 y 120 conductores que forman parte de ellas. Por otro lado, todos los conductores usan un Smartphone, mas no lo utilizan para buscar mayores ingresos en el negocio. Entonces, tomando en cuenta que el transporte en tramos cortos en el distrito a través de estos vehículos es tan frecuentes, de hecho, son los más utilizados y existe una gran demanda por ellos llega BIGA, una propuesta de negocio que busca revolucionar el transporte en tramos cortos. Nuestra propuesta de valor se basa en la seguridad y disponibilidad y responde a las necesidades actuales de la población de transportarse en vehículos con mayor confianza, seguridad y no verse expuestos a asaltos o accidentes. Sin embargo, lo que hace realmente novedosa a esta propuesta es su innovación tecnológica. Con el boom de UBER y su éxito rotundo en diferentes países, buscamos aplicar la misma fórmula, sólo que orientada a nuevas necesidades en sectores diferentes. Así, nuestra plataforma permitirá unir a conductores de mototaxis con clientes que busquen transportarse de un punto a otro. También, buscamos combatir la informalidad y dar la oportunidad a nuestros asociados de incrementar sus ingresos y redefinir su imagen ante los pasajeros, lo cual les permitirá crecer económicamente y formar parte de una red que promete ser un éxito rotundo. Tanto así es nuestro compromiso con la seguridad de nuestros clientes que aplicaremos, dentro de nuestros procesos, filtros que nos permitan contar con personal idóneo de manera tal que la experiencia de viaje sea la mejor. Sabemos también que la satisfacción de nuestros clientes y afiliados es importante, por ello contaremos con un equipo de profesionales que realizarán seguimiento constante a los servicios brindados y se encargarán de la post venta gestionando así lo necesario para fidelizar y crear relaciones a largo plazo con nuestro público. Nuestro servicio está dirigido a personas del distrito de San Juan de Lurigancho de los sectores socio-económicos B, C y D de 18 a 50 años que forman parte de la población económicamente activa y que cuentan con un Smartphone mediante el cual podrán solicitar sus viajes a través de nuestra aplicación. Queda claro que el distrito de San Juan de Lurigancho presenta grandes oportunidades de crecimiento y buscamos desarrollarnos en él para luego expandirnos hacia otros distritos que presentan condiciones similares. Nuestro proyecto necesita una inversión inicial de S/. 256177.2, siendo 60% aporte propio y asumido de manera equitativa entre cada socio del negocio y buscamos el otro 40% de inversionistas a quienes a cambio les ofrecemos una TIR de 41.61% mayor a cualquier alternativa de financiación en el mercado, un VAN de S/. 386.420 y un periodo de retorno de sólo 3 años, dos meses y 19 días. Creemos firmemente en nuestra propuesta y estamos seguros que será el próximo caso de éxito empresarial.
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Buchanan, Samuel Andrew. « The Effect of Biglycan on TNF-alpha Signaling and Innervation in the Intervertebral Disc ». Thesis, Rush University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=1581897.

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Biglycan is a small, leucine-rich repeat proteoglycan that has been shown to be elevated in the intervertebral discs (IVDs) of older adults (Cs-Szabo, 2002) and can interact with many different signaling molecules and structural proteins. TNF-alpha (TNF) is a general modulator of inflammation and may be a trigger in the chronic inflammatory response that leads to disc degeneration. Since biglycan has been shown to interact with TNFalpha (Tufvesson and Westergren-Thorsson, 2002), it may play a role in modulating its response in the IVD. Western (NFkB) and RT-PCR (MMP-1, -13, NGF and VEGF) assays were performed on both human and bovine cultured cells from IVD tissue. Treatment with biglycan alone was found to be almost indistinguishable from control groups; while biglycan in combination with TNF-alpha was able to significantly reduce transcription and expression response when compared with just TNF-alpha. Biglycan may help modulate the effects of TNF-alpha in the IVD.

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Petrik, Christian. « Untersuchung des Effekts der Deletion von Biglykan auf das kardiale "Remodelling" nach experimentellem Myokardinfarkt / ». Berlin : Mbv, 2008. http://d-nb.info/989978303/04.

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Petrik, Christian [Verfasser]. « Untersuchung des Effekts der Deletion von Biglykan auf das kardiale ‚Remodelling’ nach experimentellem Myokardinfarkt / Christian Petrik ». Berlin : Freie Universität Berlin, 2008. http://d-nb.info/1023096250/34.

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D'Antoni, Michelle. « The effect of decorin and biglycan on human airway smooth muscle cell proliferation, apoptosis and attachment ». Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103624.

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Changes in extracellular matrix (ECM) deposition along with increases in airway smooth muscle (ASM) mass are characteristic features of airway remodeling which contribute to asthma pathophysiology. Modifications in ECM include increased collagen deposition and altered proteoglycans (PGs) levels. While biglycan, a small leucine-rich PG (SLRP), deposition is generally increased, changes in decorin, another SLRP, are more variable. The interaction between the cell and the surrounding ECM triggers numerous cellular responses, which modulate functions such as survival, proliferation and differentiation. Since decorin and biglycan are known to influence cell behaviour in various types of cells, we hypothesized that these molecules would affect human airway smooth muscle cell (HASMC) function. We sought to determine the effects of decorin and biglycan on HASMC proliferation, apoptosis and attachment, and to explore the putative mechanisms responsible for these effects. Collagen type I was used as a control.Culture on a decorin matrix caused a decrease in HASMC number, which was attributed to a decrease in proliferation and an increase in apoptosis. Culture on biglycan caused an initial decrease in cell number that was not sustained. Collagen caused a significant increase in cell number. Neither biglycan nor collagen caused changes in proliferation or apoptosis. Subsequent experiments showed that cell anchorage to decorin and biglycan matrices caused abnormal focal adhesion and cytoskeletal organization, as well as, increases in alpha2 integrin protein levels as compared to cells seeded on collagen or plastic. To assess integrin activation, focal adhesion kinase (FAK) protein levels and activation were measured. FAK levels were significantly decreased compared to cells cultured on plastic or collagen I, but activation levels were unchanged.These studies demonstrate that PGs have differential effects on HASMC growth. Whereas decorin reduces ASM proliferation and increases apoptosis, biglycan has no effect. Cell-matrix adhesions were irregular in HASMCs seeded on decorin or biglycan compared to cells on collagen I or plastic. Decreases in decorin in the asthmatic airway wall, as observed in fatal asthma cases, may permit more exuberant ASM hyperplasia, suggesting that decorin's presence could serve a protective role by modulating the increase in ASM mass in asthma.
Les changements de composition de la matrice extracellulaire (MEC) ainsi que l'augmentation de la masse du muscle lisse des voies aériennes sont des caractéristiques du remodelage des voies aériennes qui contribuent à la physiopathologie de l'asthme. Les modifications de la MEC comprennent une augmentation du dépôt de collagène et un changement du niveau des protéoglycanes (PGs). Le dépôt de biglycane, un petit PG riche en leucine, est généralement plus élevé. Les changements d'expression de la décorine, un autre petit PG riche en leucine, sont, par contre, plus variables. L'interaction entre la cellule et la MEC qui l'entoure, déclenche de nombreuses réponses cellulaires, telles que la survie, la prolifération et la différenciation. Étant donné que la décorine et le biglycane peuvent influencer le comportement de différents types de cellules, nous avons émis l'hypothèse que ces molécules auraient aussi un effet sur la fonction des cellules musculaires lisses des voies aériennes. Nous avons cherché à déterminer les effets de la décorine et du biglycane sur la prolifération, l'apoptose et l'attachement des cellules musculaires lisses des voies aériennes. Nous avons aussi exploré les mécanismes putatifs qui seraient responsables de ces effets en utilisant le collagène de type I sera comme traitement de référence. La culture des cellules sur une matrice de décorine a provoqué une diminution du nombre cellules musculaires lisses des voies aériennes due à une diminution de la prolifération et à une augmentation de l'apoptose. La culture sur le biglycane a causé initialement une diminution du nombre de cellules, mais cette baise n'a pas été maintenue. Le collagène a provoqué une augmentation significative du nombre de cellules. Ni le biglycane ni le collagène n'ont induit des changements au niveau de la prolifération ou de l'apoptose. Des expériences ultérieures ont démontré que l'ancrage des cellules musculaires lisses des voies aériennes sur des matrices de décorine et de biglycane était anormal, ainsi que la formation d'adhésions focales et l'organisation du cytosquelette, en comparaison avec les cellules ensemencées sur du collagène ou du plastique. De plus, l'augmentation d'expression protéique de la sous-unité alpha2 d'intégrine a également été observée. Pour évaluer l'activation des intégrines, le niveau de protéine, ainsi que l'activation de la kinase des adhésions focales (FAK) ont été mesurés. En présence de décorine, l'expression protéique de FAK était significativement diminuée comparativement aux niveaux produits par les cellules ensemencées sur du plastique ou du collagène bien que le niveau d'activation était inchangé. Ces études démontrent que les PGs ont des effets distincts sur la croissance des cellules musculaires lisses des voies aériennes: la décorine a réduit la prolifération et a augmenté l'apoptose des cellules, tandis que le biglycane n'a pas modifié ces paramètres. Les adhésions cellules-matrice des cellules musculaires lisses des voies aériennes ensemencées sur la décorine ou le biglycane étaient irrégulières par rapport aux cellules sur le collagène de type I ou le plastique. La diminution de la quantité de décorine dans la paroi des voies aériennes observée dans les cas d'asthme fatal pourrait entraîner une hyperplasie plus prononcée des cellules musculaires lisses des voies aériennes. Ceci suggère que la présence de la décorine pourrait jouer un rôle protectif dans l'asthme, en modulant l'augmentation de la masse du muscle lisse des voies aériennes.
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Livres sur le sujet "Bigyan"

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Bucyle, Dr Morris. Bible,Quran o bigyan. Dhaka : Rangpur Publications, 1988.

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Akhtar, Sobhan Anwara. Garhosto biggan. Dhaka : Jatio shiikha Board, 1990.

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Bigan wen hua yu Bigan hou yi. Beijing : Beijing guang bo xue yuan chu ban she, 2003.

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Ray, Bhabesh. Biggan jakhan bhayangkar. Dhaka : Kakali, 1991.

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ill, Cravath Lynne Woodcock, dir. Tiny and Bigman. New York : Marshall Cavendish, 1999.

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Shahjahan, S. Shomaj biggan o bangladesh. Dhaka : Jatio shiikha Board., 1991.

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Ghosal, Shafiullah M. Shomaj biggan o Bangladesh. Dhaka : Jatio Shikha Board, 1991.

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Shahjahan, S. Shomaj biggan o Bangladesh. Dhaka : Jatioshikhakrom, 1991.

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Rahman, Atowar. Al Koran O Biggan. Calcutta : Mallick Brothers, 1997.

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Biglaw. Chicago, Illinois : ABA Publishing, American Bar Association, 2015.

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Chapitres de livres sur le sujet "Bigyan"

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Haubeck, H. D. « Biglykan ». Dans Springer Reference Medizin, 435. Berlin, Heidelberg : Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_554.

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Haubeck, H. D. « Biglykan ». Dans Lexikon der Medizinischen Laboratoriumsdiagnostik, 1. Berlin, Heidelberg : Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-49054-9_554-1.

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James, Nick, et Kana Nakano. « Challenging BigLaw ». Dans Legal Education as a Subversive Activity, 219–35. London : Routledge, 2022. http://dx.doi.org/10.4324/9781003175216-17.

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Thalmann, Florian, et Guerino B. Mazzola. « The BigBang Rubette ». Dans Computational Music Science, 183–200. Berlin, Heidelberg : Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00148-2_17.

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Mazzola, Guerino, Yan Pang, William Heinze, Kyriaki Gkoudina, Gian Afrisando Pujakusuma, Jacob Grunklee, Zilu Chen, Tianxue Hu et Yiqing Ma. « The BigBang Rubette ». Dans Computational Music Science, 143–44. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-00982-3_17.

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Chang, Ting-Yun, et Chi-Jen Lu. « TinyGAN : Distilling BigGAN for Conditional Image Generation ». Dans Computer Vision – ACCV 2020, 509–25. Cham : Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-69538-5_31.

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Gomas, Yves, et Christian H. R. Nitschelm. « Bigay, Joseph-Henri ». Dans Biographical Encyclopedia of Astronomers, 1–3. New York, NY : Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-0738-1_100784-1.

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Jaiswal, Aman, Harpreet Singh Sodhi, Mohamed Muzamil H, Rajveen Singh Chandhok, Sageev Oore et Chandramouli Shama Sastry. « Controlling BigGAN Image Generation with a Segmentation Network ». Dans Discovery Science, 268–81. Cham : Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-88942-5_21.

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Ashuha, Arseniy, et Natalia Loukachevitch. « Bigram Anchor Words Topic Model ». Dans Communications in Computer and Information Science, 121–31. Cham : Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-52920-2_12.

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Ding, Rui, Guibing Guo, Xiaochun Yan, Bowei Chen, Zhirong Liu et Xiuqiang He. « BiGAN : Collaborative Filtering with Bidirectional Generative Adversarial Networks ». Dans Proceedings of the 2020 SIAM International Conference on Data Mining, 82–90. Philadelphia, PA : Society for Industrial and Applied Mathematics, 2020. http://dx.doi.org/10.1137/1.9781611976236.10.

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Actes de conférences sur le sujet "Bigyan"

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Liu, Wanyu, Rafael Lucas D'Oliveira, Michel Beaudouin-Lafon et Olivier Rioul. « BIGnav ». Dans CHI '17 : CHI Conference on Human Factors in Computing Systems. New York, NY, USA : ACM, 2017. http://dx.doi.org/10.1145/3025453.3025524.

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Khandelwal, Pratik, Devansh Rathod, Yug Jain et Varsha Hole. « Risk Management Model using BiGAN ». Dans 2023 11th International Conference on Emerging Trends in Engineering & Technology - Signal and Information Processing (ICETET - SIP). IEEE, 2023. http://dx.doi.org/10.1109/icetet-sip58143.2023.10151650.

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Shi, Lixin, Haitham Hassanieh et Dina Katabi. « D-BigBand ». Dans the 6th annual workshop. New York, New York, USA : ACM Press, 2014. http://dx.doi.org/10.1145/2645884.2645887.

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Kłos, Weronika, Piero Coronica, Katja Seeliger et Martin N. Hebart. « Training BigGAN on an ecologically motivated image dataset ». Dans 2022 Conference on Cognitive Computational Neuroscience. San Francisco, California, USA : Cognitive Computational Neuroscience, 2022. http://dx.doi.org/10.32470/ccn.2022.1144-0.

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Zhong, Yongchao, Haonan Yang, Ying Li, Bo Yang, Xiaoqi Li, Qiuling Yue, Jinglu Hu et Yuqing Zhang. « Sybil Attack Detection in VANETs : An LSTM-Based BiGAN Approach ». Dans 2023 International Conference on Data Security and Privacy Protection (DSPP). IEEE, 2023. http://dx.doi.org/10.1109/dspp58763.2023.10404993.

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Khomutova, A. A., et E. A. Vertikova. « Assessment of collection samples of spring soft wheat in the conditions of the Non-Black Earth zone of the Russian Federation ». Dans Растениеводство и луговодство. Тимирязевская сельскохозяйственная академия, 2020. http://dx.doi.org/10.26897/978-5-9675-1762-4-2020-165.

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A comparative assessment of spring wheat varieties was carried out in the collection nursery. Under the conditions of the Non-Black Earth Zone of the Russian Federation, varieties that are promising for breeding spring soft wheat were identified. The studied varieties: Laval 19, Violetta, Biggar, Ac Taber, KVS Aquilon and Ac Carma are recommended for further study and use in the breeding program of crossbreeding.
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Evdokimova, Svetlana, et Aleksandr Zhuravlev. « ANALYSIS OF DATA FOR FORECASTING SALES BY THE MOVING AVERAGE METHOD ». Dans Modern aspects of modeling systems and processes. FSBE Institution of Higher Education Voronezh State University of Forestry and Technologies named after G.F. Morozov, 2021. http://dx.doi.org/10.34220/mamsp_44-49.

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The paper discusses methods of data analysis for forecasting sales using the example of a BigCar retail store that sells spare parts for trucks. Based on the information on sales for the calen-dar year, using the moving average method in MS Excel, the forecast values were calculated for three periods. Analysis of the calculated data showed that the smallest relative deviation is given by a four-month period.
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Alnahas, Dima, et Baris Baykant Alagoz. « Probabilistic Relational Connectivity Analysis of Bigram Models ». Dans 2019 International Artificial Intelligence and Data Processing Symposium (IDAP). IEEE, 2019. http://dx.doi.org/10.1109/idap.2019.8875980.

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Adak, Chandranath, et Xian Tao. « BigyaPAn : Deep Analysis of Old Paper Advertisement ». Dans 2021 International Joint Conference on Neural Networks (IJCNN). IEEE, 2021. http://dx.doi.org/10.1109/ijcnn52387.2021.9533299.

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Liu, Dan, Weiguo Fang, Hong Zhou et Yan Li. « Bigram Chinese Word Segmentation by Viterbi Algorithm ». Dans 2009 Sixth International Conference on Fuzzy Systems and Knowledge Discovery. IEEE, 2009. http://dx.doi.org/10.1109/fskd.2009.590.

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Rapports d'organisations sur le sujet "Bigyan"

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de Greeff, Astrid, Janneke Allaart, Carlijn de Bruijn, Dirkjan Schokker, Petra Roubos, Hélène Winkelman-Goedhart, Stéphanie Vastenhouw, Lisette Ruuls, Johanna Rebel et Mari Smits. LPS challenge in jonge biggen : VDI-12 : effect voerinterventie op biggen. Wageningen : Wageningen Livestock Research, 2016. http://dx.doi.org/10.18174/405766.

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Kluivers-Poodt, M., G. Binnendijk et M. Houthuijs. Effect van ledverlichting op dragende zeugen en gespeende biggen. Wageningen : Wageningen Livestock Research, 2018. http://dx.doi.org/10.18174/461164.

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Ouweltjes, Wijbrand, Jan Verkaik et Hans Hopster. Vroege sterfte van biggen, kalveren en melkgeitenlammeren : Percentages, oorzaken en mogelijkheden tot reductie. Wageningen : Wageningen Livestock Research, 2020. http://dx.doi.org/10.18174/511711.

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van der Peet-Schwering, C. M. C., S. E. van Nieuwamerongen, J. E. Bolhuis, G. P. Binnendijk et N. M. Soede. Groepskraamsysteem : ontwikkeling van zeugen, biggen en vleesvarkens bij spenen op 4 of 9 weken leeftijd. Wageningen : Wageningen Livestock Research, 2017. http://dx.doi.org/10.18174/409672.

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van der Peet-Schwering, C. M. C., A. I. J. Hoofs, H. van Hees, Q. Dees, G. P. Binnendijk et J. E. Bolhuis. Family Feeding Matters : effect van Familie eetsysteem en Familievoer tijdens lactatie op resultaten van zeugen en biggen tot 9 weken leeftijd. Wageningen : Wageningen Livestock Research, 2021. http://dx.doi.org/10.18174/553813.

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Mosquera, J., H. J. C. van Dooren, J. M. G. Hol, J. P. M. Ploegaert et N. W. M. Ogink. Monitoring van methaan-, ammoniak- en lachgasemissies uit stallen voor biggen, dragende zeugen en vleesvarkens : Praktijkmetingen in de periode oktober 2018-oktober 2020. Wageningen : Wageningen Livestock Research, 2022. http://dx.doi.org/10.18174/572110.

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