Thèses sur le sujet « Azetines »
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Luheshi, Abdul-Basset Nuri. « Cycloadditions to 1-azetines and 1-azetin-4-ones ». Thesis, University of Salford, 1988. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327973.
Texte intégralHemming, Karl. « Studies in the chemistry of 1-azetines and 1-azetin-4-ones ». Thesis, University of Salford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334307.
Texte intégralO'Gorman, P. A. « Some aspects of the chemistry of small ring organic molecules : 1-azetines, 1-azetidinones, 3-oxo-β-sultams and cyclopropenones ». Thesis, University of Huddersfield, 2009. http://eprints.hud.ac.uk/id/eprint/6310/.
Texte intégralPitard, Arnaud. « 1-azetines, 1,2-thiazetin-1,1-dioxides and isothiazol-1,1-dioxides as building blocks in heterocyclic synthesis : the attempted synthesis of bicyclic β-sultams ». Thesis, University of Huddersfield, 2009. http://eprints.hud.ac.uk/id/eprint/7061/.
Texte intégralLosa, Romain. « Organocatalyse redox par les phosphines : découverte de nouvelles transformations et vers le développement d'une version électrocatalytique ». Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASF014.
Texte intégralThis thesis work focused on organocatalysis using trivalent phosphines, compounds which play a crucial role in many chemical transformations and widely used for several organic syntheses. One of the two research axes of this thesis focused on the innovative development of organocatalytic methodologies using trivalent phosphines. We focused on P(III)/P(III) or P(III)/P(V) processes for the synthesis of oxygen or nitrogen-containing heterocycles. After developing a version stoichiometric in phosphine, the methodology was optimized by making it catalytic. A more detailed study enabling the synthesis of 2-azetine derivatives, promoted and then catalysed by phosphines, was developed during this thesis. The products thus obtained were valued in organic synthesis and tested biologically. Finally, the second line of research in this thesis focused directly on the electroreduction of phosphine oxides. In today's environmental context, it is imperative to render the reactions promoted by phosphine catalytic in phosphine, by introducing a reducing agent into the reaction medium. In order to progress towards the development of electrocatalytic reactions, we used electrochemistry for the reduction of phosphine oxides, thus inscribing our work in a more virtuous chemistry approach
Pearson, Christopher I. « Lithiated azetidine and azetine chemistry ». Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:cf3c942f-80de-4092-a38d-11006ccbb9ce.
Texte intégralYoshizawa, Akina. « Azetidines for asymmetric synthesis ». Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8719/.
Texte intégralThaxton, Amber. « Synthesis of Novel Azetidines ». ScholarWorks@UNO, 2013. http://scholarworks.uno.edu/td/1764.
Texte intégralKloesges, Johannes. « Novel Chemistry of aziridines and azetidines ». Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509969.
Texte intégralPancholi, Alpa Kishor. « Synthesis of substituted azetidines and spirocyclic diazetidines ». Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/102606/.
Texte intégralPORTAL, MARTINE. « Syntheses de pyrrolidines et azetidines polyfonctionnalisees homochirales d'interet biologique ». Paris 6, 1993. http://www.theses.fr/1993PA066211.
Texte intégralFeula, Antonio. « Synthesis of azetidines and pyrrolidines : towards medicinal chemistry and organocatalysis applications ». Thesis, University of Birmingham, 2013. http://etheses.bham.ac.uk//id/eprint/4214/.
Texte intégralMichaud, Thierry. « Synthese d'heterocycles azotes enatiomeriquement purs (aziridines, azetidines, isoxazoles) au depart de monosaccharides ». Clermont-Ferrand 2, 1995. http://www.theses.fr/1995CLF21711.
Texte intégralUNGUREANU, IONA MARIA. « La reactivite des aziridines et azetidines revisitee ou nouvelles voies d'acces aux heterocycles ». Université Louis Pasteur (Strasbourg) (1971-2008), 2000. http://www.theses.fr/2000STR13083.
Texte intégralBaeg, Jin-Ook. « Palladium(II)-catalyzed regiospecific and stereospecific cycloaddition reactions of aziridines and azetidines with heterocumulenes ». Thesis, University of Ottawa (Canada), 1995. http://hdl.handle.net/10393/9676.
Texte intégralHama, Salih Mariwan Abdulla. « Synthesis of azetidines, γ-lactams, fused furan bispyrrolidines and 2-pyrazolines : towards medical application ». Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6838/.
Texte intégralRabasso, Nicolas. « Nouvelles méthodologies pour la synthèse enantioselective d'hétérocycles azotés de quatre à huit chainons ». Paris 6, 2003. http://www.theses.fr/2003PA066274.
Texte intégralOdom, Lindsay D. « Reactions of diazoketones catalyzed by rhodium (II) : synthesis of functionalized azetidines and tetrahydrofurans as potential protein kinase C inhibitors / ». Full text available from ProQuest UM Digital Dissertations, 2006. http://0-proquest.umi.com.umiss.lib.olemiss.edu/pqdweb?index=0&did=1331395991&SrchMode=1&sid=8&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1218744025&clientId=22256.
Texte intégralSlaughter, Kimari. « Synthesis and Development of Potential CB1 Receptor Neutral Antagonists ». ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1483.
Texte intégralBarré, Baptiste. « Fonctionnalisation d'hétérocycles par des réactions métallo-catalysées ». Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066461.
Texte intégralCross-coupling reactions, as Prof. K. C. Nicolaou said “have changed the way we think about synthesis”. Indeed, cross-coupling reactions are powerful tools to access easily and rapidly to a library of compounds in the context of medicinal chemistry. Palladium-catalysed cross-coupling rules the field and was recognized by the Nobel Prize in 2010 but, since its discovery, others metals have appeared as good alternatives to the expensive and toxic palladium salts such as copper, nickel, cobalt and iron salts. In medicinal chemistry, heterocycles are essential moieties since they are found in a great number of drugs on the market. It is always a challenge for organic chemists to develop new methods to produce motifs with interesting pharmacological properties such as substituted azetidines, pyrrolidines and oxetanes. sp3 Halides are challenging substrates for cross-coupling because the oxidative addition of the metal in the C-X bond is difficult and because side reactions can take place like -hydride elimination or dehydrohalogenation. Nevertheless, cobalt and iron are suitable catalysts to perform cross-coupling reactions on sp3 halides. Herein, we would like to report two catalytic systems allowing the cross-coupling between heterocyclic alkyl halides and Grignard reagents using cobalt and iron salts. A mechanistic study on cobalt-catalysed cross-coupling reaction between halides and Grignard reagents will be also presented
Nocquet, Pierre-Antoine. « Vers la synthèse d'une nouvelle classe d'iminosucres conformationnellement contraints : ouverture d'azétidines, cyclisation 4-exo-trig et C-H amination catalytique ». Thesis, Strasbourg, 2013. http://www.theses.fr/2013STRAF047/document.
Texte intégralPrevious studies in our group has shown that α-1-C-nonyl-1,5-dideoxy-1,5-imino-D-xylitol was a strong inhibitor of β-glucocerebrosidase, the enzyme involved in Gaucher disease. It was supposed that the inverted chair conformation of this compound could partially explain its high affinity with the target glycosydase.The goal of this PhD work was the synthesis of a new class of iminosugars based on 1-azaspiro[3.3]heptane structures, as conformationally strained analogues of our lead in the iminoxylitol series. During the course of our synthetic study, new azetidine ring-opening tandem reaction leading to spirocyclopropyl γ-lactames has been discovered. The most promising strategy evaluated led to the highly stereoselective formation of a tetrasubstituted cyclobutane via a SmI2-mediated radical reaction − leading to the synthesis of the first exemples of 4-membered carbasugars − then to the formation of the azaspiranic carbon of our target by way of rhodium-catalyzed C-H amination reaction
Kern, Nicolas. « Réactivité d'azacycles en catalyse à l'or ». Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAF012/document.
Texte intégralOrganometallic catalysis is a key tool of modern chemical synthesis. lts use is ubiquitous in the preparation of bulk or fine chemicals, in particular for the assembly of carbon-carbon and carbon-heteroatom bonds. Besides its overall efficiency, it responds to the responsible criteria of energy and atom economy, the reduction of waste, risk, and financial costs needed to perform a chemical reaction.ln just a few years, homogenous gold catalysis has emerged as an invaluable tool for the fast generation of molecular complexity. lndeed, it allows the strong electrophilic activation of unsaturated hydrocarbon moieties (e.g. alkynes or alienes). During this PhD thesis, we focused our studies on the use of gold's pi acidity as weil as its "classical" - but less discussed - Lewis acid character for the triggering of cascade reactions.Starting from acetylenic heterocycles, we targeted the synthesis of polycyclic compounds. The milder reactivity of silver complexes was also found useful in these reactions, as weil as in the deprotection of methoxybenzyl ethers
Malik, Sarika. « Application of sulfur ylides in the synthesis of dihydrobenzofurens and azetidines ». Thesis, 2009. http://localhost:8080/iit/handle/2074/3692.
Texte intégralArora, Anjali. « Studies towards the synthesis of Azetidines using sulfur ylides and related compounds ». Thesis, 1994. http://localhost:8080/iit/handle/2074/3535.
Texte intégralSharma, Raman Lata. « Student on the reaction of Sulfur ylides with Aziridines and related compounds-an approach to azetidines ». Thesis, 1989. http://localhost:8080/iit/handle/2074/3502.
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