Littérature scientifique sur le sujet « Auxiliary channels »
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Articles de revues sur le sujet "Auxiliary channels"
Dvorak, Nolan M., Paul A. Wadsworth, Pingyuan Wang, Jia Zhou et Fernanda Laezza. « Development of Allosteric Modulators of Voltage-Gated Na+ Channels : A Novel Approach for an Old Target ». Current Topics in Medicinal Chemistry 21, no 10 (17 juin 2021) : 841–48. http://dx.doi.org/10.2174/1568026621666210525105359.
Texte intégralFlockerzi, Veit, et Bernd Fakler. « TR(i)P Goes On : Auxiliary TRP Channel Subunits ? » Circulation Research 134, no 4 (16 février 2024) : 346–50. http://dx.doi.org/10.1161/circresaha.123.323178.
Texte intégralHoshi, Toshinori, Rong Xu, Shangwei Hou, Stefan H. Heinemann et Yutao Tian. « A point mutation in the human Slo1 channel that impairs its sensitivity to omega-3 docosahexaenoic acid ». Journal of General Physiology 142, no 5 (14 octobre 2013) : 507–22. http://dx.doi.org/10.1085/jgp.201311061.
Texte intégralZhou, Zijing, Xiaonuo Ma, Yiechang Lin, Delfine Cheng, Navid Bavi, Genevieve A. Secker, Jinyuan Vero Li et al. « MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels ». Science 381, no 6659 (18 août 2023) : 799–804. http://dx.doi.org/10.1126/science.adh8190.
Texte intégralJones, Lisa P., Shao-kui Wei et David T. Yue. « Mechanism of Auxiliary Subunit Modulation of Neuronal α1E Calcium Channels ». Journal of General Physiology 112, no 2 (1 août 1998) : 125–43. http://dx.doi.org/10.1085/jgp.112.2.125.
Texte intégralJiao, Yunjing, Qijing Lin, Kun Yao, Na Zhao, Dan Xian, Fuzheng Zhang, Qingzhi Meng, Bian Tian et Zhuangde Jiang. « Design of High-Precision Parallel AWG Demodulation System ». Micromachines 14, no 9 (25 août 2023) : 1662. http://dx.doi.org/10.3390/mi14091662.
Texte intégralDvorak, Nolan M., Cynthia M. Tapia, Aditya K. Singh, Timothy J. Baumgartner, Pingyuan Wang, Haiying Chen, Paul A. Wadsworth, Jia Zhou et Fernanda Laezza. « Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na+ Channel 1.6 Enables Isoform-Selective Modulation ». International Journal of Molecular Sciences 22, no 24 (17 décembre 2021) : 13541. http://dx.doi.org/10.3390/ijms222413541.
Texte intégralSinha, Ashish, Haodong Gu, Namwoon Kim et Renu Emile. « Signaling effects and the role of culture : movies in international auxiliary channels ». European Journal of Marketing 53, no 10 (7 octobre 2019) : 2146–72. http://dx.doi.org/10.1108/ejm-09-2017-0587.
Texte intégralBrown, Austin L., Zhiwen Liao et Miriam B. Goodman. « MEC-2 and MEC-6 in the Caenorhabditis elegans Sensory Mechanotransduction Complex : Auxiliary Subunits that Enable Channel Activity ». Journal of General Physiology 131, no 6 (26 mai 2008) : 605–16. http://dx.doi.org/10.1085/jgp.200709910.
Texte intégralWilliams, Brittany, Josue A. Lopez, J. Wesley Maddox et Amy Lee. « Functional impact of a congenital stationary night blindness type 2 mutation depends on subunit composition of Cav1.4 Ca2+ channels ». Journal of Biological Chemistry 295, no 50 (8 octobre 2020) : 17215–26. http://dx.doi.org/10.1074/jbc.ra120.014138.
Texte intégralThèses sur le sujet "Auxiliary channels"
Yasuda, Takahiro. « Modulation of calcium channel function and toxin sensitivity by auxiliary subunits / ». [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18052.pdf.
Texte intégralMolinarolo, Steven. « Biochemical techniques for the study of voltage-gated sodium channel auxiliary subunits ». Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6217.
Texte intégralRobinson, Philip. « Targeting of voltage-gated calcium channels to lipid rafts : the role of auxiliary alpha2/delta-1 subunits ». Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/targeting-of-voltagegated-calcium-channels-to-lipid-rafts-the-role-of-auxiliary-alpha2delta1-subunits(db84049c-1445-4486-9e31-34fa4110daf6).html.
Texte intégralZhao, Juan. « Biophysical characterization of neuronal and skeletal muscle sodium channels, and their regulation by auxiliary beta subunits ». Thesis, Université Laval, 2012. http://www.theses.ulaval.ca/2012/28793/28793.pdf.
Texte intégralVoltage-gated Na channels are responsible for the rising phase of action potentials, and consist of a pore-forming α subunit and one or more auxiliary β subunits. The α subunit alone is sufficient for the functional expression of Na channels, however, β subunits modulate the location, expression and functional properties of α subunits. My thesis will focus on three neuronal Na channels (Nav1.6, Nav1.7 and Nav1.8) and one skeletal muscle Na channel (Nav1.4). Neuronal Na channel are key players in the impulse propagation along axon. Nav1.7 and Nav1.8 are the main Na channels expressed in DRG neurons, and their altered expression and modulation following injury and inflammation play a major role in nociception and chronic pain. Nav1.6 is highly concentrated at nodes of Ranvier, and has a critical role not only in saltatory conduction but also in high-frequency repetitive firing. Skeletal muscle Na channel Nav1.4 is the initiator of muscle contraction. Mutations in Nav1.4 cause skeletal muscle channelopathies. Guiding questions for our investigations were: 1) How do auxiliary β subunits regulate peripheral nerve Na channel Nav1.6 and Nav1.8? 2) What is the underlying biophysical defect of M1476I, a novel founder SCN4A mutation associated with painful cold-induced myotonia in French Canadians? 3) What is the biophysical characterization of the Nav1.6 persistent current? 4) What is the expression pattern of auxiliary subunits, and how do β subunits regulate Nav1.7 in DRG neurons? We addressed these questions by multiple approaches including patch clamp techniques for whole-cell and single-channel recordings in heterologous expression systems; immunohistochemistry, single-cell RT-PCR and immunoprecipitation in DRG neurons. Firstly, we employed single-cell RT-PCR of acutely dissociated DRG neurons to identify the expression of β1-4 subunits in small-diameter sensory neurons. Our results indicated that small-diameter DRG neurons widely expressed Nav1.6 and Nav1.8 channels and β1-β3 subunits. Co-expression studies were used to assess the regulation of Nav1.6 and Nav1.8 by β subunits. The β1 subunit induced a significant increase in the current density of Nav1.8 when co-expressed in HEK293 cells, but had no effect on that of Nav1.6. In addition, the C-terminal domain of β1 was involved in the modulation of Nav1.8 channel based on the results of experiments with β1/β2 chimeras harboring various regions of the strongly regulating β1 together with the weakly regulating β2 subunit. Secondly, we investigated the biophysical defects of M1476I mutation in Nav1.4 channels using whole-cell patch-clamp technique in tsA201 cells. M1476I mutant channel exhibited similar biophysical defects compared with other PAM-causing mutations, including an increased persistent current of Nav1.4, a slower current decay, a positive shift of fast inactivation, and an accelerated recovery from fast inactivation. Lowering the temperature slowed the kinetics for both wide-type and mutant channels, and worsened the defective fast inactivation of M1476I channels by further increasing the amplitude of the persistent current. Mexiletine helps relieve myotonia in M1476I carriers by effectively suppressing the increased persistent current, except for the use-dependent block. However, mexiletine had a reduced effectiveness on the use-dependent block of M1476I channels, and that was associated with a faster recovery from mexiletine block of mutant channels. Thirdly, we characterized the whole-cell and single-channel properties of Nav1.6 persistent currents expressed in HEK293 cells. We noted that Nav1.6 persistent current was highly sensitive to the composition of the internal solution, and persistent current was rarely detectable when CsF instead of CsCl was used. By substituting CsF for CsCl in the intracellular solution, we showed that Nav1.6 persistent current in the whole-cell configuration was 3–5% of the peak transient current. This amplitude of persistent current was similar to the ratio between peak and persistent open probability observed in the single-channel recording, indicating that the occurrence of late channel reopenings accounts for the persistent macroscopic Na current typical of Nav1.6. Finally, we employed a combination of single-cell RT-PCR, immunocytochemistry and immunoprecipitation to investigate subunit expression in subpopulations of sensory neurons. subunits were differentially expressed in small (2, 3) and large (1, 2) DRG neurons. Nav1.7 mRNA was significantly co-expressed with the 2 and 3 subunits in the same population of small-diameter DRG neurons. They formed stable protein-protein interactions and co-localized within the plasma membranes of neurons.When co-expressed in HEK293 cells, 3 and 1 subunits shifted activation and inactivation curves respectively and induced a marked increase in Nav1.7 window current. Our data indicated a preferential expression of subunits in small and large DRG neurons and a subunit-specific Nav1.7 regulation in these subpopulations of sensory neurons.
Tableau d'honneur de la FÉSP
Saponaro, A. C. « THE AUXILIARY SUBUNIT TRIP8B ANTAGONIZES THE BINDING OF CAMP TO HCN2 CHANNELS THROUGH AN ALLOSTERIC MECHANISM ». Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/229903.
Texte intégralZhou, Wei. « Structural and functional studies on the regulation of K+ channels by local anesthetics and intracellular auxiliary subunits / ». Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2004. http://wwwlib.umi.com/cr/ucsd/fullcit?p3142460.
Texte intégralSoubrane, Camille Hélène. « Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels ». Thesis, University of Reading, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658003.
Texte intégralTerhag, Jan [Verfasser], Michael [Gutachter] Hollmann et Guiscard Friedrich Aldous [Gutachter] Seebohm. « Auxiliary subunits of voltage-gated Calcium channels as modulators of ionotropic glutamate receptors / Jan Terhag ; Gutachter : Michael Hollmann, Guiscard Friedrich Aldous Seebohm ». Bochum : Ruhr-Universität Bochum, 2016. http://d-nb.info/111670952X/34.
Texte intégralDespang, Patrick Sebastian [Verfasser], Dirk [Akademischer Betreuer] Isbrandt et Markus [Akademischer Betreuer] Plomann. « Autism-related mutations of auxiliary Cavβ-subunits : electrophysiological characterization of effects on the function of voltage-gated calcium channels / Patrick Sebastian Despang ; Akademische Betreuer : Dirk Isbrandt, Markus Plomann ». Köln : Deutsche Zentralbibliothek für Medizin, 2020. http://d-nb.info/1215226047/34.
Texte intégralStephani, Friederike Lene Brigitte [Verfasser]. « α2δ3 is the preferred auxiliary α2δ subunit of Cav2.1 channels in spiral ganglion neurons and is required for development of auditory nerve fiber synapses / Friederike Lene Brigitte Stephani ». Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2020. http://d-nb.info/1216877823/34.
Texte intégralChapitres de livres sur le sujet "Auxiliary channels"
Borowik, Sergej, et Henry M. Colecraft. « Voltage-Gated Calcium Channel Auxiliary β Subunits ». Dans Voltage-Gated Calcium Channels, 73–92. Cham : Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-08881-0_4.
Texte intégralObermair, Gerald J., et Bernhard E. Flucher. « Neuronal Functions of Auxiliary Calcium Channel Subunits ». Dans Modulation of Presynaptic Calcium Channels, 29–59. Dordrecht : Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6334-0_2.
Texte intégralMatthes, Jan, et Stefan Herzig. « Auxiliary β-Subunits of L-Type Ca2+ Channels in Heart Failure ». Dans Pathologies of Calcium Channels, 255–75. Berlin, Heidelberg : Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-40282-1_14.
Texte intégralDolphin, Annette C., et Gerald J. Obermair. « Regulation of Calcium Channels and Synaptic Function by Auxiliary α2δ Subunits ». Dans Voltage-Gated Calcium Channels, 93–114. Cham : Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-08881-0_5.
Texte intégralMolinarolo, Steven, Daniele Granata, Vincenzo Carnevale et Christopher A. Ahern. « Mining Protein Evolution for Insights into Mechanisms of Voltage-Dependent Sodium Channel Auxiliary Subunits ». Dans Voltage-gated Sodium Channels : Structure, Function and Channelopathies, 33–49. Cham : Springer International Publishing, 2017. http://dx.doi.org/10.1007/164_2017_75.
Texte intégralWeik, Martin H. « auxiliary channel ». Dans Computer Science and Communications Dictionary, 90. Boston, MA : Springer US, 2000. http://dx.doi.org/10.1007/1-4020-0613-6_1173.
Texte intégralRamachandran, Nitya, et P. Yogesh. « Modified Auxiliary Channel Diffie Hellman Encrypted Key Exchange Authentication Protocol ». Dans Information Technology and Mobile Communication, 417–21. Berlin, Heidelberg : Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-20573-6_74.
Texte intégralPietrobon, D. « Introduction ». Dans Guidebook to Protein Toxins and Their Use in Cell Biology, 167–69. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198599555.003.0058.
Texte intégralLevitan, Irwin B., et Leonard K. Kaczmarek. « Diversity in the Structure and Function of Ion Channels ». Dans The Neuron, 127–50. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199773893.003.0007.
Texte intégralLeidenheimer, N. J., J. E. Dildy-Mayfield et R. A. Harris. « Effect of Ethanol on Voltage-Gated Ion Channels ». Dans The Pharmacology of Alcohol and Alcohol Dependence, 335–55. Oxford University PressNew York, NY, 1996. http://dx.doi.org/10.1093/oso/9780195100945.003.0010.
Texte intégralActes de conférences sur le sujet "Auxiliary channels"
Fertonani, D., et T. M. Duman. « Upper Bounding the Deletion Channel Capacity by Auxiliary Memoryless Channels ». Dans ICC 2009 - 2009 IEEE International Conference on Communications. IEEE, 2009. http://dx.doi.org/10.1109/icc.2009.5199553.
Texte intégralWu, Yiting, Chuansheng Yang, Chao Wang, Hongming Chen et Qihong Ye. « Low-light image enhancement combining dehazing and auxiliary channels ». Dans 3rd International Conference on Advanced Algorithms and Signal Image Processing (AASIP 2023), sous la direction de Kannimuthu Subramaniam et Pavel Loskot. SPIE, 2023. http://dx.doi.org/10.1117/12.3005867.
Texte intégralWang, Shengde, Zhenqiang Yao, Hong Shen et Guohu Luo. « Numerical Analysis on the Hydraulic Performance of the Auxiliary Impeller in Large Capacity Canned-Motor Pump ». Dans ASME 2018 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/imece2018-87285.
Texte intégralLi, Wenming, Fanghao Yang, Tamanna Alam, Benli Peng, Xiaopeng Qu et Chen Li. « Enhanced Flow Boiling in Microchannels Using Auxiliary Channels and Multiple Micronozzles ». Dans ASME 2016 5th International Conference on Micro/Nanoscale Heat and Mass Transfer. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/mnhmt2016-6712.
Texte intégralPhung, Cao Vien, Anna Engelmann, Thomas Kuerner et Admela Jukan. « Improving THz Quality-of-Transmission with Systematic RLNC and Auxiliary Channels ». Dans 2020 IEEE International Conference on Communications Workshops (ICC Workshops). IEEE, 2020. http://dx.doi.org/10.1109/iccworkshops49005.2020.9145148.
Texte intégralHalevi, Tzipora, et Nitesh Saxena. « On pairing constrained wireless devices based on secrecy of auxiliary channels ». Dans the 17th ACM conference. New York, New York, USA : ACM Press, 2010. http://dx.doi.org/10.1145/1866307.1866319.
Texte intégralShinmoto, Yasuhisa, Shinichi Miura, Koichi Suzuki, Yoshiyuki Abe et Haruhiko Ohta. « Development of Advanced High Heat Flux Cooling System for Power Electronics ». Dans ASME 2009 InterPACK Conference collocated with the ASME 2009 Summer Heat Transfer Conference and the ASME 2009 3rd International Conference on Energy Sustainability. ASMEDC, 2009. http://dx.doi.org/10.1115/interpack2009-89082.
Texte intégralPetrov, Nikolay V., Azat O. Ismagilov, Egor N. Oparin, Vladimir S. Shumigai, Anastasiia K. Lappo-Danilevskaia, Boris A. Nasedkin et Anton N. Tsypkin. « Ghost imaging with auxiliary multiplex channels : a review of the latest results ». Dans Speckle 2023 : VIII International Conference on Speckle Metrology, sous la direction de Yechuan Zhu, Wei Wang et Weiguo Liu. SPIE, 2024. http://dx.doi.org/10.1117/12.3021804.
Texte intégralHan, Yafei, et Guolong Liang. « Blind Multi-User Detection Based on Auxiliary Particle Filter in Fading CDMA Channels ». Dans 2009 International Conference on E-Business and Information System Security (EBISS). IEEE, 2009. http://dx.doi.org/10.1109/ebiss.2009.5137947.
Texte intégralMiura, Shinichi, Yukihiro Inada, Yasuhisa Shinmoto et Haruhiko Ohta. « Development of Cooling System for a Large Area at High Heat Flux by Using Flow Boiling in Narrow Channels ». Dans ASME 2009 7th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2009. http://dx.doi.org/10.1115/icnmm2009-82279.
Texte intégralRapports d'organisations sur le sujet "Auxiliary channels"
Little, Charles, et David Biedenharn. Technical assessment of the Old, Mississippi, Atchafalaya, and Red (OMAR) Rivers : channel geometry analysis. Engineer Research and Development Center (U.S.), août 2022. http://dx.doi.org/10.21079/11681/45147.
Texte intégralPokryshen, Dmytro A., Evgeniy H. Prokofiev et Albert A. Azaryan. Blogger and YouTube services at a distant course “Database management system Microsoft Access”. [б. в.], septembre 2019. http://dx.doi.org/10.31812/123456789/3272.
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