Bibliographies thématiques / Australian Animal Health Laboratory

Littérature scientifique sur le sujet « Australian Animal Health Laboratory »

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Publié le 26 juillet 2024

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Articles de revues sur le sujet "Australian Animal Health Laboratory"

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DELLA-PORTA, AJ. « The role of the Australian Animal Health Laboratory ». Australian Veterinary Journal 66, no 12 (décembre 1989) : 455–59. http://dx.doi.org/10.1111/j.1751-0813.1989.tb13576.x.

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Lowenthal, John. « Overview of the CSIRO Australian Animal Health Laboratory ». Journal of Infection and Public Health 9, no 3 (mai 2016) : 236–39. http://dx.doi.org/10.1016/j.jiph.2016.04.007.

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Selleck, Paul. « A brief history of AAHL ». Microbiology Australia 41, no 4 (2020) : 210. http://dx.doi.org/10.1071/ma20056.

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The CSIRO Australian Animal Health Laboratory (AAHL) was officially opened on 1 April 1985. After that day the laboratory switched to secure mode and has operated as such ever since. AAHL was constructed to be the primary national diagnostic facility for exotic animal diseases but has expanded its role to become a national and international reference laboratory for many diseases. AAHL has supported disease control within the region by providing training, reagents and proficiency testing, both within Australia and internationally. AAHL’s role has evolved even further to include a focus on one-health which resulted in AAHL being renamed the Australian Centre for Disease Preparedness (ACDP) in March 2020.
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Wright, Lynda. « Biobanks – serum and cells – human and animals ». Microbiology Australia 40, no 3 (2019) : 138. http://dx.doi.org/10.1071/ma19037.

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The Australian Animal Health Laboratory (AAHL), CSIRO is a high-containment facility and a vital part of Australia's national biosecurity infrastructure. AAHL closely collaborates with veterinary and human health agencies globally, as approximately 70 per cent of emerging infectious diseases in people originate in animals. The facility is designed to allow scientific research into the most dangerous infectious agents in the world and contains a large collection of serum and cell lines.
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Scott, Pam. « THE SOCIAL SHAPING OF A LABORATORY : THE ESTABLISHMENT OF THE AUSTRALIAN ANIMAL HEALTH LABORATORY ». Prometheus 6, no 2 (décembre 1988) : 249–62. http://dx.doi.org/10.1080/08109028808629314.

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Scott, Pam. « Culling technological white elephants : Lessons from the Australian Animal Health Laboratory ». Science and Public Policy 16, no 1 (février 1989) : 47–51. http://dx.doi.org/10.1093/spp/16.1.47.

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FORMAN, AJ. « Recent developments in diagnosis of exotic disease at the Australian Animal Health Laboratory ». Australian Veterinary Journal 70, no 5 (mai 1993) : 161–63. http://dx.doi.org/10.1111/j.1751-0813.1993.tb06118.x.

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RICHARDS, RB, TM ELLIS et JG ALLEN. « Government Animal Health Laboratory Services in Western Australia ». Australian Veterinary Journal 70, no 9 (septembre 1993) : 321–23. http://dx.doi.org/10.1111/j.1751-0813.1993.tb00870.x.

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Doyle, Kevin. « Consultation, Conflict, Cooperation and Controversy : a history of the establishment of CSIRO's Australian Animal Health Laboratory - by Snowdon B ». Australian Veterinary Journal 86, no 1-2 (janvier 2008) : 42. http://dx.doi.org/10.1111/j.1751-0813.2007.00240.x.

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Zemanova, Miriam A. « Crucial but Neglected : Limited Availability of Animal Welfare Courses in Education of Wildlife Researchers ». Animals 13, no 18 (13 septembre 2023) : 2907. http://dx.doi.org/10.3390/ani13182907.

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Animal welfare is a subject of increasing scientific and ethical concern in today’s society, crucial for the well-being of animals used in research and the integrity of scientific data. Equipping researchers in the life science disciplines with a science-based knowledge of animal welfare, behaviour, physiology, and health is, therefore, essential. Nevertheless, previous studies evaluating animal welfare education focused on veterinary, laboratory, or farm animal science. Consequently, the aim of this study was, for the very first time, to map the prevalence of animal welfare courses in the university education of ecologists, wildlife biologists, and conservation managers in Europe, Canada, the USA, Australia, and New Zealand. A comprehensive assessment of 1548 universities was conducted, resulting in the identification of 596 relevant programs at the bachelor’s and master’s levels. Analysis of the curricula revealed that only 1% of the programs offered a formal course on animal welfare, while 65% provided courses on animal behaviour, 59% on animal physiology, and 34% on animal health. However, the majority of these courses were listed as electives rather than mandatory components of the programs. These results underscore the need for universities to incorporate more formal and obligatory education in animal welfare in order to better prepare future ecologists, wildlife biologists, and conservation managers for the challenges of working with wildlife.
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Thèses sur le sujet "Australian Animal Health Laboratory"

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Tahmasebi-Sarvestani, Abdolghafar. « Innervation of the temporomandibular joint : an experimental animal model using Australian merino sheep / ». Title page, abstract and contents only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09pht1284.pdf.

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Lutz, Eric Anthony. « Human and Animal Exposure to Airborne Methicillin-resistant Staphylococcus aureus (MRSA) : Laboratory Evaluations and Veterinary Hospital Pilot Study ». The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1276101615.

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Cardoso, Célia Virginia Pereira. « Avaliação dos processos de criação e manutenção de animais de laboratório : uma ação contínua para a qualidade no Sistema Nacional d e Vigilância Sanitária ». reponame:Repositório Institucional da FIOCRUZ, 2014. https://www.arca.fiocruz.br/handle/icict/8206.

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Submitted by Alexandre Sousa (alexandre.sousa@incqs.fiocruz.br) on 2014-08-18T17:50:41Z No. of bitstreams: 1 Tese Celia Virginia.pdf: 3990091 bytes, checksum: 5a2ed5b390413f56573cd6e58c049834 (MD5)
Made available in DSpace on 2014-08-18T17:50:42Z (GMT). No. of bitstreams: 1 Tese Celia Virginia.pdf: 3990091 bytes, checksum: 5a2ed5b390413f56573cd6e58c049834 (MD5) Previous issue date: 2014
Fundação Oswaldo Cruz. Centro de Criação de Animais de Laboratório
O Sistema Nacional de Vigilância Sanitária (SNVS), ao qual se vincula a Agência Nacional de Vigilância Sanitária (Anvisa) desempenha um papel essencial na saúde pública brasileira, em especial por intermédio dos Laboratórios Centrais de Saúde Pública (Lacens) que, em alguns casos, utilizam os animais de laboratório para a realização de testes de controle biológico de cosméticos, medicamentos, saneantes, alimentos, dentre outros produtos em saúde. Com o objetivo de avaliar o grau da qualidade dos referidos animais foi realizado um estudo nos biotérios de criação e experimentação dos Lacens de três estados brasileiros, por meio de visitação e de um levantamento detalhado das características estruturais e de bem-estar animal encontradas nos biotérios. A primeira abordagem trata das implicações éticas no uso dos animais e da terminologia empregada para identificação dos mesmos.Os resultados da pesquisa de campo são registrados e resumidos em quadros.Em seguida apresenta-se uma proposta de Boas Práticas de Biotério (BPB) com base em vasto levantamento bibliográfico e na experiência profissional adquirida pela autora.A discussão e a conclusão do estudo apontam para evidências críticas sob a institucionalização dos biotérios no SNVS, suas implicações do ponto de vista ético, legal, estrutural, de manejo e de bem-estar, que refletem diretamente na baixa qualidade dos animais. Como consequência desse cenário, aponta-se um viés de precariedade nas ações da vigilância sanitária no país. São considerados, entretanto, os avanços alcançados pela Ciência em Animais de Laboratório (CAL), nos últimos anos, e as perspectivas futuras de estabelecimento de uma Política Nacional de Biotérios que, somada a um crescimento ainda maior da CAL e à integração da normatização das BPB ao sistema da Anvisa, possam contribuir de forma significativa para a obtenção da qualidade desejada e necessária dos animais de laboratório utilizados, não somente no SNVS, como nasdemais instituições científicas do Brasil
The National Health Surveillance System (SNVS), which binds to the National Health Surveillance Agency (ANVISA) plays an essential role in the Brazilian public health, especially through the Central Public Health Laboratories (Lacens) that in some cases, using laboratory animals for conducting biological control testing cosmetics, medicines, sanitizing, food, among other health products. With the objective of evaluating the degree of quality of those animals, a study was conducted in laboratory animal care and research units of Lacens three Brazilian states, through visitation and a detailed survey of the structural and animal welfare characteristics found in these units. The first approach deals with the ethical implications of the use of animals and the terminology used for its identification. The field survey results are registered and summarized in tabular form.Then we will introduce a proposal of Good Practice of Laboratory Animal Unit (BPB) based on extensive literature review and professional experience gained by the author. The discussion and conclusion of the study point to critical evidence in the institutionalization of these units in SNVS, implications of the ethical point of view, cool, structural, management and welfare, which directly reflect the low quality ofthe animals. As a consequence of this scenery, points to a bias in the actions of the precarious health surveillance in the country. Are considered, however, the progress made by the Laboratory Animal Science (CAL), in recent years, and future prospects of establishing a National Policy for Laboratory Animal Units that, plus a further growth of CAL and the integration of standardization of BPB to ANVISA system, can contribute significantly to achieving the desired and required quality of laboratory animals used, not only in SNVS, as in other scientific institutions in Brazil.
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Tahmasebi-Sarvestani, Abdolghafar. « Innervation of the temporomandibular joint : an experimental animal model using Australian merino sheep / Abdolghafar Tahmasebi-Sarvestani ». Thesis, 1997. http://hdl.handle.net/2440/18981.

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Includes bibliographies.
1 v. : ill. ; 30 cm.
The present study provides a detailed account of the anatomical and neurohistological structure of the temporomandibular joint (TMJ) in foetal and adult Australian Merino sheep. The purpose is to describe the innervation of the joint and to determine the possible roles of both afferent receptor structures and neuropeptides in the pathophysiology of experimentally induced osteoarthritis.
Thesis (Ph.D.)--University of Adelaide, Dept. of Anatomical Science, 1997
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Stenske, Katherine Anne. « Comparison of Fecal Escherichia coli From Dogs and Their Owners ». 2008. http://etd.utk.edu/2008/August2008Dissertations/StenskeKatherineAnne.pdf.

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Abeysekera, Irushi Shamalka. « Effect of Epigallocatechin-3-gallate on Skeletal and Cognitive Phenotypes in a Down Syndrome Mouse Model ». Thesis, 2014. http://hdl.handle.net/1805/5628.

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Indiana University-Purdue University Indianapolis (IUPUI)
Down syndrome (DS), a genetic disorder that affects ~1 in 700 live births, is caused by trisomy of human chromosome 21 (Hsa21). Individuals with DS are affected by a wide spectrum of phenotypes which vary in severity and penetrance. However, cognitive and skeletal impairments can be commonly observed in all individuals with DS. To study these phenotypes, we utilized the Ts65Dn mouse model that carries three copies of approximately half the gene orthologs found on Hsa21 and exhibit similar phenotypes as observed in humans with DS. Individuals with DS and Ts65Dn mice have deficits in bone mineral density (BMD), bone architecture, bone strength, learning and memory. Over-expression of DYRK1A, a serine-threonine kinase encoded on Hsa21, has been linked to deficiencies in DS bone homeostasis and cognition. Epigallocatechin-3-gallate (EGCG), an aromatic polyphenol found in high concentrations in green tea, is a selective inhibitor of DYRK1A activity. Normalization of DYRK1A activity by EGCG therefore may have the potential to ameliorate skeletal and cognitive deficits. We hypothesized that supplements containing EGCG obtained from health food stores/ online vendors will not be as effective as EGCG from a chemical company in correcting bone deficits associated with DS. Our results suggest that EGCG improves the bone mineral density of trisomic femurs significantly better than the supplements while the EGCgNOW supplement from NOW FOODS improves trabecular and cortical bone structure. The results from HPLC analysis of supplements showed the presence of other catechins in EGCgNOW and degradation analysis revealed the rapid degradation of supplements. Therefore we hypothesize that the presence of EGCG degradation products and other green tea catechins in supplements may play a role in the differential skeletal effects we observed. We further hypothesized that a three week treatment of adolescent mice with EGCG will lead to an improvement in the learning and memory deficits that are observed in trisomic animals in comparison to control mice. However, our results indicate that three weeks of low-dose EGCG treatment during adolescence is insufficient to improve hippocampal dependent learning and memory deficits of Ts65Dn mice. The possibility remains that a higher dose of EGCG that begins at three weeks but lasts throughout the behavioral test period may result in improvement in learning and memory deficit of Ts65Dn mice.
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Livres sur le sujet "Australian Animal Health Laboratory"

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J, Della-Porta Antony, Australian Development Assistance Bureau et International Seminar on Virus Diseases of Veterinary Importance in South-East Asia and the Western Pacific (1984 : Australian National Animal Health Laboratory)., dir. Veterinary viral diseases : Their significance in South-East Asia and the Western Pacific : proceedings of an international seminar on virus diseases of veterinary importance in South-East Asia and the Western Pacific held at Australian National Animal Health Laboratory, CSIRO, Geelong, Australia, 27-30 August 1984. Sydney : Academic Press, 1985.

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Laboratory), International Seminar on Virus Diseases of Veterinary Importance in South-East Asia and the Western Pacific (1984 Australian National Animal Health. Veterinary viral diseases : Their significance in South-East Asia and the western Pacific : proceedings of an International Seminar on Virus Diseases of Veterinary Importance in South-East Asia and the Western Pacific, held at Australian National Animal Health Laboratory, CSIRO, Geelong, Australia, 27-30 August 1984. Sydney : Academic Press, 1985.

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Newton, Gordon. Australian bush medics. [Leichhardt, N.S.W.] : Short Stop Press, 2013.

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Great Britain. Education Service Advisory Committee., dir. Health and safety in animal facilities. London : H.M.S.O., 1992.

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Gay, William I. Health benefits of animal research. [Washington, D.C.] : Foundation for Biomedical Research, 1985.

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United States. Public Health Service., dir. Public Health Service policy on humane care and use of laboratory animals. Bethesda, Md : Office for Protection from Research Risks, National Institutes of Health, 1986.

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National Institutes of Health (U.S.). Office of Laboratory Animal Welfare. Public Health Service policy on humane care and use of laboratory animals. 2e éd. Bethesda, MD (6705 Rockledge Dr., Bethesda 20892-7982) : Office of Laboratory Animal Welfare, National Institutes of Health, Dept. of Health and Human Services, 2002.

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Hansen, Axel Kornerup. Handbook of laboratory animal bacteriology. Boca Raton : CRC Press, 2000.

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Bode, Nina B. Divine laboratory. Montreal, Quebec : N.B. Bode, 1995.

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Cork, S. C. The veterinary laboratory and field manual : A guide for veterinary laboratory technicians and animal health advisors. Nottingham, U.K : Nottingham University Press, 2002.

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Chapitres de livres sur le sujet "Australian Animal Health Laboratory"

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De Keulenaer, K. « Chapter 25. Animal Health ». Dans Good Clinical, Laboratory and Manufacturing Practices, 353–67. Cambridge : Royal Society of Chemistry, 2007. http://dx.doi.org/10.1039/9781847557728-00353.

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Khatri, Neeraj, Priyanka, Ashish Kumar Dubey, Ram Bharti et Bhupinder Singh Chopra. « Occupational Health Hazards and Disaster Management in Laboratory Animal Facilities ». Dans Essentials of Laboratory Animal Science : Principles and Practices, 585–606. Singapore : Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-0987-9_24.

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Carroll, Marilyn E., Warren K. Bickel et Stephen T. Higgins. « Nondrug incentives to treat drug abuse : Laboratory and clinical developments. » Dans Animal research and human health : Advancing human welfare through behavioral science., 139–54. Washington : American Psychological Association, 2001. http://dx.doi.org/10.1037/10441-010.

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Kaul, Sherin, Rajni Singh, Sharanya Kamaraju et Pankaj Suman. « Changing Trends in Immunosensing Technologies and Their Commercial Aspects in Animal Health and Welfare ». Dans Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing, 141–61. Singapore : Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-5823-8_8.

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Grabowski, John. « Complementary examination of medications for drug abuse : Preclinical, human laboratory, and clinical research. » Dans Animal research and human health : Advancing human welfare through behavioral science., 155–75. Washington : American Psychological Association, 2001. http://dx.doi.org/10.1037/10441-011.

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Rush, Craig R., Nancy A. Ator, Cathy A. Simpson et Warren K. Bickel. « Behavioral pharmacology of commonly abused drugs : Concordance between laboratory studies conducted with animals and humans. » Dans Animal research and human health : Advancing human welfare through behavioral science., 101–14. Washington : American Psychological Association, 2001. http://dx.doi.org/10.1037/10441-007.

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Perry, Brian, Bernard Bett, Eric Fèvre, Delia Grace et Thomas Fitz Randolph. « Veterinary epidemiology at ILRAD and ILRI, 1987-2018. » Dans The impact of the International Livestock Research Institute, 208–38. Wallingford : CABI, 2020. http://dx.doi.org/10.1079/9781789241853.0208.

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Abstract This chapter describes the activities of the International Livestock Research Institute (ILRI) and its predecessor, the International Laboratory for Research on Animal Diseases (ILRAD) from 1987 to 2018. Topics include scientific impacts; economic impact assessment; developmental impacts; capacity development; partnerships; impacts on human resources capacity in veterinary epidemiology; impacts on national animal health departments and services; impacts on animal health constraints in developing countries; impacts on ILRI's research and strategy; the introduction of veterinary epidemiology and economics at ILRAD; field studies in Kenya; tick-borne disease dynamics in eastern and southern Africa; heartwater studies in Zimbabwe; economic impact assessments of tick-borne diseases; tick and tick-borne disease distribution modelling; modelling the infection dynamics of vector-borne diseases; economic impact of trypanosomiasis; the epidemiology of resistance to trypanocides; the development of a modelling technique for evaluating control options; sustainable trypanosomiasis control in Uganda and in the Ghibe Valley of Ethiopia; spatial modelling of tsetse distributions; preventing and containing trypanocide resistance in the cotton zone of West Africa; rabies research; the economic impacts of rinderpest control; applying economic impact assessment tools to foot and mouth disease (FMD) control, the southern Africa FMD economic impact study; economic impacts of FMD in Peru, Colombia and India; economic impacts of FMD control in endemic settings in low- and middle-income countries; the global FMD research alliance (GFRA); Rift Valley fever; economic impact assessment of control options and calculation of disability-adjusted life years (DALYs); RVF risk maps for eastern Africa; land-use change and RVF infection and disease dynamics; epidemiology of gastrointestinal parasites; priorities in animal health research for poverty reduction; the Wellcome Trust Epidemiology Initiatives; the broader economic impact contributions; the responses to highly pathogenic avian influenza; the International Symposium on Veterinary Epidemiology and Economics (ISVEE) experience, the role of epidemiology in ILRAD and ILRI and the impacts of ILRAD and ILRI's epidemiology; capacity development in veterinary epidemiology and impact assessment; impacts on national animal health departments and services; impacts on animal health constraints in developing countries and impacts on ILRI's research and strategy.
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Egan, Suzanne. « Deploying Rose and Abi-Rached to ‘Make Sense’ of the Rise of the ‘Brain Sciences’ in the Field of Violence Against Women ». Dans Using Social Theory in Higher Education, 77–90. Cham : Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-39817-9_6.

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AbstractThe neurosciences have been afforded increasing explanatory power in relation to a broad range of social issues, in fields as diverse as education, health, child protection, and criminal justice. Rose and Abi-Rached (2013) have termed the 2000s the decade of the ‘brain sciences’, the decade in which neuroscience dispersed from the laboratory and entered key sites of social and political discourse. This chapter engages with Rose and Abi-Rached’s work to explore aspects of the uptake of a neurobiological approach to trauma in feminist sexual assault organisations. This is a field of practice, which with its origins in the second wave women’s movement continues to be governed by an explicitly political social change agenda. Yet, in the Australian context, it has also been an ‘early adopter’ of the neuroscience of trauma. In this chapter, I first briefly the source of my interest in this issue as well as my engagement and discomfort with the positioning of trauma discourse in much feminist academic work. I then share some of my struggles in deciding how to use Rose and Abi-Rached’s ideas to help me progress my own thinking and research.
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Stoskopf, Michael K. « Biology and Health of Laboratory Fishes ». Dans Laboratory Animal Medicine, 885–907. Elsevier, 2002. http://dx.doi.org/10.1016/b978-012263951-7/50023-5.

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Rabinowitz, Peter M., Rafael Y. Lefkowitz, Lisa A. Conti, Carrie A. Redlich et Benjamin J. Weigler. « Occupational Health of Laboratory Animal Workers ». Dans Laboratory Animal Medicine, 1381–402. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-409527-4.00030-4.

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Actes de conférences sur le sujet "Australian Animal Health Laboratory"

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Shindel, S. « 370. Characterization of Noise and Noise Exposure in Three Laboratory Animal-Care Facilities ». Dans AIHce 1996 - Health Care Industries Papers. AIHA, 1999. http://dx.doi.org/10.3320/1.2765049.

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Mazanov, Ivan, Kseniia Ezhova, Anna Levina et Anna Mudrich. « Optoelectronic system development for conducting laboratory experiments on the analysis of animal behavior ». Dans Optics in Health Care and Biomedical Optics XIII, sous la direction de Qingming Luo, Xingde Li, Ying Gu et Dan Zhu. SPIE, 2023. http://dx.doi.org/10.1117/12.2686815.

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Li, Jane, Christian Muller-Tomfelde et Toni Robertson. « Designing for Distributed Scientific Collaboration : A Case Study in an Animal Health Laboratory ». Dans 2012 45th Hawaii International Conference on System Sciences (HICSS). IEEE, 2012. http://dx.doi.org/10.1109/hicss.2012.199.

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Kube, H., L. Wengenroth, J. Gerlich, G. Dietrich-Gümperlein, R. Schierl, D. Nowak et K. Radon. « 1707b From workplace to home environment : spreading of mouse allergens by laboratory animal workers ». Dans 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.144.

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Perov, S. Yu, et S. A. Askerova. « THE NEUROENDOCRINE SYSTEM RESPONSE OF 2-5 G COMMUNICATION ELECTROMAGNETIC FIELD ANIMAL EXPOSURE ». Dans The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-398-402.

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Abstract: Background. The neuroendocrine effect on the hypothalamus-pituitary-adrenal cortex axis is significant example stressor of electromagnetic exposure for biological object. Aim. The neuroendocrine effect investigation of multi-frequency electromagnetic field laboratory animals’ exposure from 2-5 generations cellular base stations Methods. The neuroendocrine status evaluated by corticosterone and adrenocorticotropic hormone (ACTH) concentrations in blood exposed and sham rats. ACTH and corticosterone rat blood assessed by immunoenzyme method. Results. The results of the multi-frequency electromagnetic field laboratory animals’ exposure from 2-5 generations cellular base stations in a chronic experiment showed wave-like changes in the hypothalamic-pituitary-adrenal function. These changes are manifested in an immediate increase in corticosteroids secretion and depression of the corticosteroid response to normal or subnormal levels. After 3 month chronic exposure there was a secondary rise in hormonal secretion.
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Hwang, Sung Ho, Ye Ji Ko, Donguk Park, Seung Hon Ham et Chung Sik Yoon. « O46-6 Characteristics of seasonal distribution of airborne endotoxin and (1-3)-β-d-glucan in laboratory animal rooms in seoul, south korea ». Dans Occupational Health : Think Globally, Act Locally, EPICOH 2016, September 4–7, 2016, Barcelona, Spain. BMJ Publishing Group Ltd, 2016. http://dx.doi.org/10.1136/oemed-2016-103951.237.

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Rossi, Paolo, Cristina Castagnetti, Stefano Cattini, Giorgio Di Loro, Francesca Grassi, Luigi Parente, Sara Righi, Luigi Rovati, Roberto Simonini et Alessandro Capra. « Monitoring of underwater animal forests : geometry and biometry ». Dans 5th Joint International Symposium on Deformation Monitoring. Valencia : Editorial de la Universitat Politècnica de València, 2022. http://dx.doi.org/10.4995/jisdm2022.2022.13891.

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The development and testing of innovative technologies and automated data analysis methodologies offer tools for investigations in numerous scenarios including the monitoring of complex marine ecosystems and the direct and indirect effects of climate change on natural heritage. In the underwater environment, the creation of products with accurate metric and colorimetric content is a scientific and technological challenge, that can offer tools for new investigations including the monitoring of ecosystems and the study of biodiversity. The research group developed a technological solution consisting of a remotely operating platform and a measuring system that includes RGB and fluorescence optical sensors for the 3D reconstruction of the underwater environment and the study of the health-state of investigated species. The proposed solution aspires to high-accuracy multiscale reconstruction of underwater animal forests with a special focus on metric content. Methodologies and technical solutions for the management and calibration of the system have been developed: the design of proper calibration frames and the fluorescence sensor, the choice of a proper illumination system, the implementation of the system on a customizable Remotely Operating Vehicle, the integration of the different sensors, the combination of metric and colorimetric results for monitoring the occurred deformations and the health status. The results of laboratory activities and preliminary tests on field tests are discussed.
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Veshchemova, T. E., et G. V. Masaltsev. « EVALUATION OF TOXICITY AND ANTICHOLINESTERASE EFFECT OF A METHOMYL-CONTAINING DRUG WHEN ADMINISTERED TO LABORATORY ANIMALS VIA VARIOUS ROUTES ». Dans The 4th «OCCUPATION and HEALTH» International Youth Forum (OHIYF-2022). FSBSI «IRIOH», 2022. http://dx.doi.org/10.31089/978-5-6042929-6-9-2022-1-44-48.

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Despite a wide range of insecticidal activity and high efficiency, carbamate insecticides require a highly professional approach to its use due to inherent high toxicity to bees, warm-blooded animals and humans, and undesirable feature of its exhibiting toxic properties not immediately, but after prolonged systematic contact. The goal of this work was to evaluate the toxicity of the methomyl-based drug (25% of the active substance) and its anticholinesterase effect in animal experiments when administered via various routes (rats and rabbits). Materials and methods: Experimental toxicological studies were carried out in accordance with the methodological documents: Guidelines for the hygienic assessment of new pesticides, Guideline R 1.2.3156-13 "Assessment of the toxicity and danger of chemicals and their mixtures for human health." Results: Acute oral and dermal toxicity thresholds, possible irritation and cumulative properties of the formation were evaluated. According to the results, the methomyl-based drug exhibits the highest toxicity when administered intragastrically. When applied to mucous membranes of the eye, the it causes symptoms characteristic of carbamate poisoning. When applied to intact skin of laboratory animals, the drug does not exhibit toxic effects.
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Caraba, Marioara Nicoleta, Ion Valeriu Caraba, Adrian Sinitean, Gabi Dumitrescu et Roxana Popescu. « ADMINISTRATION OF OCHRATOXIN A TO LABORATORY ANIMALS AND ITS EFFECTS ON BLOOD PARAMETERS ». Dans 23rd SGEM International Multidisciplinary Scientific GeoConference 2023. STEF92 Technology, 2023. http://dx.doi.org/10.5593/sgem2023/6.1/s25.12.

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Mycotoxins are agents with different and complex chemical structures, with toxic effects for humans and animals. They can be present in feed and food, although in very small quantities, mycotoxins have a negative effect on the health of animals and people. Ochratoxins are mycotoxins intensively studied in recent years due to their toxicity on the animal and human body; these toxins show nephrotoxic, immunotoxic and myelotoxic, neurotoxic and carcinogenic effects. Thirty male rats of the Sprague- Dawley breed were divided into 3 groups who received through feed doses of of ochratoxin A (OTA): 0.5 mg OTA/kg BW, 1 mg OTA/kg BW and non OTA (control group). The blood samples collected on the anticoagulant were subjected to the analysis of the main components: hemoleucogram and biochemical parameters. The variations of the determined biochemical parameters (alanine aminotransferase, aspartat aminotransferase, serum creatinin, serum urea and blood urea nitrogen) indicate changes in the kidney and liver function in the animals from the experimental groups compared to the control group. The parameters of the hemoleucogram count also register variations depending on the administered dose of OTA.
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Belaya, О. V. « EXPERIMENTAL STUDY OF 2-5G BASE STATION ELECTROMAGNETIC FIELD CHRONIC EXPOSURE NERVOUS SYSTEM EFFECT TYPOLOGICAL FEATURES ». Dans The 4th «OCCUPATION and HEALTH» International Youth Forum (OHIYF-2022). FSBSI «IRIOH», 2022. http://dx.doi.org/10.31089/978-5-6042929-6-9-2022-1-20-24.

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Introduction: the new exposure to electromagnetic fields biological effect assessment is actual with respect to the expected of electromagnetic environment complication due to joint operation of various generation cellular communication systems. The character of biological reaction can be mediated by individual typological characteristics of the organism. The goal: to study the 2–5G base stations electromagnetic field chronic exposure effect to nervous system functional state of laboratory animals with regard to their typological features. Methods: the rats body weight registration and "open field" test were carried out before the start of exposure, after each month of 24-hour exposure (500 µW/cm2, 2-5G mobile standards, 4 months) and 1 month after the end of exposure with accounting of high-entropic and low-entropic animal subgroups. Results: the results indicate a multidirectional effect of rats’ nervous system in groups of various entropy types. According to behavioral parameters and body weight dynamics, there was an inhibition of research activity and functional state of the high-entropic animals after 2 months of exposure. Conclusion: Results can be assumed that used experimental exposure type had a suppression affect to central nervous system functional state with higher responsiveness of animals that initially have a predominance of excitation over inhibition processes.
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Rapports d'organisations sur le sujet "Australian Animal Health Laboratory"

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Jung, Carina, Matthew Carr, Denise Lindsay, Eric Fleischman et Chandler Roesch. Microbiome perturbations during domestication of the green June beetle (Cotinis nitida). Engineer Research and Development Center (U.S.), février 2022. http://dx.doi.org/10.21079/11681/43342.

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Animal-associated microbiomes are critical to the well-being and proper functioning of the animal host, but only limited studies have examined in-sect microbiomes across different developmental stages. These studies revealed large shifts in microbiome communities, often because of significant shifts in diet during insects’ life cycle. Establishing insect colonies as model laboratory organisms and understanding how to properly feed and care for animals with complex and dynamic life cycles requires improved data. This study examined laboratory raised green June beetles (Cotinis nitida) captured from the field upon emergence from pupae. Starting with wild-caught adults, two generations of beetles were reared in the laboratory, ending with an entirely laboratory raised generation of larvae. The study compared the microbiomes of each generation and the microbiomes of larvae to adults. This study suggests that a diet of commercial, washed fruit for adults and commercial, packaged, organic alfalfa meal for larvae resulted in depauperate gut microbiome communities. Fermentative yeasts were completely absent in the laboratory-raised adults, and major bacterial population shifts occurred from one generation to the next, coupled with high morbidity and mortality in the laboratory-raised generation. Providing laboratory-raised beetles fresh-collected fruit and the larvae field-harvested detritus may therefore vastly improve their health and survival.
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James, Christian, Stephen J. James, Bukola A. Onarinde, Ronald A. Dixon et Nicola Williams. Critical review of AMR risks arising as a consequence of using biocides and certain heavy metals in food animal production. Food Standards Agency, août 2023. http://dx.doi.org/10.46756/sci.fsa.ich936.

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Antimicrobial resistance (AMR) is the resistance of a microorganism to an antimicrobial agent (a substance that kills or stops the growth of microorganisms) that was originally effective for treatment of infections caused by it. As a result standard antimicrobial drug treatments may become ineffective, lead to infections persisting, increasing the risk of spread to others, and negative clinical outcomes. AMR is a major public health issue worldwide and it is estimated that unless action is taken to tackle AMR, the global impact of AMR could be 10 million deaths annually from drug-resistant infections by 2050 and cost up to US $100 trillion in terms of cumulative lost global production (O’Neill, 2016). Addressing the public health threat posed by AMR is a national strategic priority for the UK and led to the Government publishing both a 20-year vision of AMR (Opens in a new window) and a 5-year (2019 to 2024) AMR National Action Plan (NAP) (Opens in a new window), which sets out actions to slow the development and spread of AMR. Intensive food animal production plays an important role in the development and spread of AMR and is one of many routes by which consumers can be exposed to antimicrobial-resistant bacteria. This review was carried out to help increase our understanding of whether, and to what extent, the use of biocides (disinfectants and sanitisers) and heavy metals (used in feed and other uses) in animal production leads to the development and spread of AMR within the food chain (a subject highlighted in the NAP). Whether this could potentially lead to greater consumer exposure to antimicrobial-resistant bacteria present in our food, either directly through consumption of foods derived from animals that have undergone treatment (for example from the use of heavy metals in animal feed) or indirectly (for example from exposure of crops to contaminated soil or ground water) is not known. Focused searching of three literature databases (Web of Science (Opens in a new window), Scopus (Opens in a new window), and MEDLINE (Opens in a new window)) was undertaken, supplemented by additional records identified through other sources. Due to the range of publications identified and different laboratory methodologies used in these studies no statistical analysis was possible, so instead, a narrative approach was taken to their review and to the review of supplementary materials. We conclude that there is published evidence that the release of chemicals like biocides (in particular disinfectants) and/or heavy metals from food animal production have the potential to contribute to the selection, emergence, and spread of AMR (as bacteria or genes) that could be acquired by consumers, and that this could present a potential risk to the consumer as a result. The published evidence is sparse and there are significant knowledge gaps (as detailed in this report). Currently there are insufficient data for a comprehensive and quantitative assessment of risk, and a need for focussed in-field studies (as detailed in this report) to be carried out to fill these knowledge gaps and confirm whether there is an actual risk.
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Shpigel, Nahum, Raul Barletta, Ilan Rosenshine et Marcelo Chaffer. Identification and characterization of Mycobacterium paratuberculosis virulence genes expressed in vivo by negative selection. United States Department of Agriculture, janvier 2004. http://dx.doi.org/10.32747/2004.7696510.bard.

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Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of a severe inflammatory bowel disease (IBD) in ruminants, known as Johne’s disease or paratuberculosis. Johne’s disease is considered to be one of the most serious diseases affecting dairy cattle both in Israel and worldwide. Heavy economic losses are incurred by dairy farmers due to the severe effect of subclinical infection on milk production, fertility, lower disease resistance and early culling. Its influence in the United States alone is staggering, causing an estimated loss of $1.5 billion to the agriculture industry every year. Isolation of MAP from intestinal tissue and blood of Crohn's patients has lead to concern that it plays a potential pathogenic role in promoting human IDB including Crohn’s disease. There is great concern following the identification of the organism in animal products and shedding of the organism to the environment by subclinically infected animals. Little is known about the molecular basis for MAP virulence. The goal of the original proposed research was to identify MAP genes that are required for the critical stage of initial infection and colonization of ruminants’ intestine by MAP. We proposed to develop and use signature tag mutagenesis (STM) screen to find MAP genes that are specifically required for survival in ruminants upon experimental infection. This research projected was approved as one-year feasibility study to prove the ability of the research team to establish the animal model for mutant screening and alternative in-vitro cell systems. In Israel, neonatal goat kids were repeatedly inoculated with either one of the following organisms; MAP K-10 strain and three transposon mutants of K-10 which were produced and screened by the US PI. Six months after the commencement of inoculation we have necropsied the goats and taken multiple tissue samples from the jejunum, ileum and mesenteric lymph nodes. Both PCR and histopathology analysis indicated on efficient MAP colonization of all the inoculated animals. We have established several systems in the Israeli PI’s laboratory; these include using IS900 PCR for the identification of MAP and using HSP65-based PCR for the differentiation between MAV and MAP. We used Southern blot analysis for the differentiation among transposon mutants of K-10. In addition the Israeli PI has set up a panel of in-vitro screening systems for MAP mutants. These include assays to test adhesion, phagocytosis and survival of MAP to/within macrophages, assays that determine the rate of MAPinduced apoptosis of macrophages and MAP-induced NO production by macrophages, and assays testing the interference with T cell ã Interferon production and T cell proliferation by MAP infected macrophages (macrophage studies were done in BoMac and RAW cell lines, mouse peritoneal macrophages and bovine peripheral blood monocytes derived macrophages, respectively). All partners involved in this project feel that we are currently on track with this novel, highly challenging and ambitious research project. We have managed to establish the above described research systems that will clearly enable us to achieve the original proposed scientific objectives. We have proven ourselves as excellent collaborative groups with very high levels of complementary expertise. The Israeli groups were very fortunate to work with the US group and in a very short time period to master numerous techniques in the field of Mycobacterium research. The Israeli group has proven its ability to run this complicated animal model. This research, if continued, may elucidate new and basic aspects related to the pathogenesis MAP. In addition the work may identify new targets for vaccine and drug development. Considering the possibility that MAP might be a cause of human Crohn’s disease, better understanding of virulence mechanisms of this organism might also be of public health interest as well.
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Osburn, Bennie, Marius Ianconescu, Geoffrey Akita et Rozalia Kaufman. Rapid, Sensitive Bluetongue Virus Serogroup and Serotype Detection Using Polymerase Chain Reaction. United States Department of Agriculture, septembre 1995. http://dx.doi.org/10.32747/1995.7612836.bard.

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The objectives of this proposal were to enhance animal health by 1) development of a BTV serogroup diagnostic assay using polymerase chain reaction (PCR) and 2) development of a BTV serotype specific diagnostic PCR assay. A PCR assay for diagnosis of bluetongue virus (BTV) serogroup from clinical samples meeting the criteria of objective 1 was developed. This PCR assay is more sensitive than virus isolation and has been adopted by both the U.S. and Israeli collaborating laboratories of this project, as well as at least one other U.S. laboratory for routine diagnosis of BTV infection in ruminants. The basic BTV PCR protocol has also become an essential tool in BTV molecular research in both collaborating laboratories. During development of the BTV serotype specific PCR we had the opportunity to investigate a nationwide outbreak of abortions and fatal disease in dogs in the U.S. purportedly due to BTV infection via a BTV contaminated canine vaccine. The BTV serogroup PCR was integral in confirming BTV in tissues from affected dogs and in lots of the suspect vaccine. This led to the first published report of BTV infection in dogs. We discovered that BTV can produce silent persistent infection in canine cell culture. This indicated a need for more stringent screening of biologics for occult BTV infection. A novel mixed cell culture method was developed to identify occult BTV and other occult viral infection cell cultures. Serotype specific primers for PCR detection of all U.S. BTV serotypes and two Israel serotypes (BTV-2 and 10) have been evaluated and are available. A subsequent collaboration would logically include sequencing of the L2 genes of Israel BTV-4, 6 and 16, allowing incorporation of these Israel BTV serotypes into a multiplex PCR assay.
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D’Agostino, Martin, Nigel Cook, Liam O’Connor, Annette Sansom, Dima Semaan, Anne Wood, Sue Keenan et Linda Scobie. Optimising extraction and RT-qPCR-based detection of hepatitis E virus (HEV) from pork meat and products. Food Standards Agency, juillet 2023. http://dx.doi.org/10.46756/sci.fsa.ylv958.

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Hepatitis E is an infection of the liver caused by the hepatitis E virus (HEV). HEV infection usually produces a mild disease, hepatitis E. However, disease symptoms can vary from no apparent symptoms to liver failure. There are 4 main types (genotypes) of the virus that cause concern in humans. Genotypes 1 and 2 infections are mainly restricted to humans but 3 and 4 can be identified in numerous other animal species including pigs. Transmission routes of HEV genotypes 3 and 4 have been identified to include the consumption of food products derived from infected animals and shellfish, and via transfusion of infected blood products. Hepatitis E infection is still an emerging issue in the UK and there is evidence to suggest an association of this virus with undercooked pork and pork products. Currently, there is no standardized method for evaluating the stability of HEV that may be present in food during cooking processes. There is also lack of a suitable method that can detect only infectious HEV. The proposed project aimed to address a key gap in resources for methodology related to the detection of HEV in pork and pork products. Currently the lack of a standardised method for the detection of HEV has resulted in individual laboratories either utilising their own methods or adapting methods from previously published work. This leads to a high degree of variability between the interpretation of results and does nothing to progress or provide benefit to the food industry. By interrogating the existing published methods, the project sought to refine and optimise elements of existing protocols in order to enhance the performance characteristics of the method and to simplify the methodology wherever possible. The aim was to produce a validated method which is both robust and repeatable which can be easily integrated into food laboratories capable of performing virus related work. Overall, the final method chosen was devoid of hazardous reagents and utilised easily accessible equipment. To verify the robustness of the method, an international collaborative trial was performed, with 4 UK and 3 European participant laboratories. The participating laboratories conducted analyses of pork liver samples artificially contaminated with various levels of HEV (including uncontaminated samples). The trial showed that the HEV DETECT method was just as reproducible between laboratories as it was repeatable within a laboratory. It is envisaged that the developed system will be put forward as a suitable candidate for ISO certification as a standard method. The establishment of these methods in UK laboratories could result in the availability of independent testing services for both domestic and imported pork /pork-based products. The availability of this method is in essence innovation. This work is essential to industry to help support further research to ensure that public health safety and confidence in pork and other “HEV risk” food products is maintained and improved.
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Addressing African Swine Fever : Protocols and Guidelines for Laboratory Diagnosis. WOAH (World Organisation for Animal Health), mai 2024. http://dx.doi.org/10.20506/asf.3475.

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The World Organisation for Animal Health (WOAH), the Food and Agriculture Organization of the United Nations (FAO) and other partners have been actively working in countries affected or at risk of incursion by African swine fever (ASF). This manual is an updated and expanded version of guidance first published in 2020 following the emergence of ASF in China, other Asian countries, and countries of the Pacific and Caribbean regions.
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An overview of the Futures Literacy Laboratory on “The Futures of Climate Responses, 2040”, Organized by the World Organisation for Animal Health (WOAH) with the UN Educational, Scientific and Cultural Organization (UNESCO). O.I.E (World Organisation for Animal Health), janvier 2023. http://dx.doi.org/10.20506/9789295121546.

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