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Articles de revues sur le sujet "Art. 55 c.p"
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Iannuzzo, Gabriella, Marco Gentile, Alessandro Bresciani, Vania Mallardo, Anna Di Lorenzo, Pasquale Merone, Gianluigi Cuomo et al. « Inhibitors of Protein Convertase Subtilisin/Kexin 9 (PCSK9) and Acute Coronary Syndrome (ACS) : The State-of-the-Art ». Journal of Clinical Medicine 10, no 7 (5 avril 2021) : 1510. http://dx.doi.org/10.3390/jcm10071510.
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Acute Coronary Syndrome (ACS) remains one of the most frequent causes of morbidity and mortality in the world. Although the age- and gender-adjusted incidence of ACS is decreasing, the mortality associated with this condition remains high, especially 1-year after the acute event. Several studies demonstrated that PCSK9 inhibitors therapy determine a significant reduction of major adverse cardiovascular events (MACE) in post-ACS patients, through a process of plaque modification, by intervening in lipid metabolism and platelet aggregation and finally determining an improvement in endothelial function. In the EVACS (Evolocumab in Acute Coronary Syndrome) study, evolocumab allows >90% of patients to achieve LDL-C < 55 mg/dL according to ESC/EAS guidelines compared to 11% of patients who only receive statins. In the EVOPACS (EVOlocumab for Early Reduction of low-density lipoprotein (LDL)-cholesterol Levels in Patients With Acute Coronary Syndromes) study, evolocumab determined LDL levels reduction of 40.7% (95% CI: 45.2 to 36.2; p < 0.001) and allowed 95.7% of patients to achieve LDL levels <55 mg/dL. In ODYSSEY Outcome trial, alirocumab reduced the overall risk of MACE by 15% (HR = 0.85; CI: 0.78–0.93; p = 0.0003), with a reduced risk of all-cause mortality (HR = 0.85; CI: 0.73–0.98: nominal p = 0026), and fewer deaths for coronary heart disease (CHD) compared to the control group (HR = 0.92; CI: 0.76–1.11; p = 0.38). The present review aimed at describing the beneficial effect of PCSK9 inhibitors therapy early after ACS in reducing LDL circulating levels (LDL-C) and the risk of major adverse cardiovascular events, which was very high in the first year and persists higher later after the acute event.
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Iddi, Shabani, Caroline A. Minja, Vitus Silago, Asteria Benjamin, Jastine Mpesha, Shimba Henerico, Benson R. Kidenya, Stephen E. Mshana et Mariam M. Mirambo. « High Human Immunodeficiency Virus (HIV) Viral Load and Coinfection with Viral Hepatitis Are Associated with Liver Enzyme Abnormalities among HIV Seropositive Patients on Antiretroviral Therapy in the Lake Victoria Zone, Tanzania ». AIDS Research and Treatment 2019 (2 juin 2019) : 1–6. http://dx.doi.org/10.1155/2019/6375714.
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Background. Liver enzymes abnormalities have been found to be common among patients on antiretroviral treatment (ART). Apart from the effects of ART on these changes, other factors that can potentially contribute to the abnormal levels of these enzymes have been found to vary in different geographical locations. This study investigated factors associated with liver enzymes abnormalities among human immunodeficiency virus (HIV) infected individuals on ART from the Lake Victoria zone, Tanzania. Methods. A cross-sectional study involving a total of 230 sera from HIV seropositive patients from different regions of the Lake Victoria zone was carried out in July 2017. All samples with required variables/parameters such as age, sex, ART regimen, and residence were serially included in the study. Hepatitis B virus (HBV) and Hepatitis C virus (HCV) detection and liver enzymes assays (alanine transaminase (ALAT) and aspartate transaminase (ASAT)) were assessed following the standard procedures. Data were analyzed by using STATA version 13. Results. The median age of the study participants was 38 (interquartile range [IQR]:30-48) years. The overall prevalence of abnormal liver enzymes was 43.04% (99/230, 95% CI: 36.6-49.3). A total of 26.09% (60/230) had elevated ASAT while 23.9% (55/230) patients had elevated ALAT levels. ASAT levels were significantly high among patients with high HIV viral load (P= 0.002) while ALAT levels were significantly high among those coinfected with hepatitis C virus (P=0.017) and hepatitis B virus (P<0.001). Conclusion. A significant proportion of HIV seropositive individuals on ART have abnormal levels of liver enzymes, which is significantly associated with high HIV viral load and viral hepatitis. This calls for the need to emphasize screening of viral hepatitis and provision of appropriate management among HIV seropositive individuals in this setting.
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Ayșe, Atay, Najafova Lamia, Kurtulmus Huseyin Mehmet et Üşümez Aslihan. « The micro-shear bond strength of two different repair systems to indirect restorative materials ». STOMATOLOGY EDU JOURNAL 7, no 4 (2020) : 233–41. http://dx.doi.org/10.25241/stomaeduj.2020.7(4).art.1.
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Introduction The aim of this study was to evaluate the micro-shear bond strength (μSBS) of different repair systems (Clearfil Repair, iGOS Repair) to restorative materials for CAD/CAM (Cerasmart, Lava Ultimate, InCoris TZI , VITA Suprinity, VITA Mark II, IPS e.max CAD, IPS Empress CAD). Methodology The 140 1.2 mm-thick specimens were prepared from CAD/CAM blocks (n=20) and thermocycled (10,000 cycles, 5–55°C, dwell time 20s). The specimens were randomly divided into two groups according to the repair system: Clearfil Repair (40% phosphoric acid+mixture of Clearfil Porcelain Bond Activator and Clearfil SE Bond Primer+Clearfil SE Bond+CLEARFIL MAJESTY ES-2) and iGOS Repair (40% phosphoric acid+ Multi Primer LIQUID+ iGOS Bond+ iGOS Universal). The composite resins were polymerized. All specimens were stored in distilled water at 37°C for 24 hours. The μSBS test was performed with a micro-shear testing machine (at 1 mm/min). The data were analyzed using two-way ANOVA, Tukey’s multiple comparison tests at a significance level of p<0.05. Each failure modes were examined under a stereomicroscope at×16 magnification. Results The type of CAD/CAM restorative material and repair system showed a significant effect on the μSBS (p<0.05). Specimens repaired with the iGOS Repair system showed the highest μSBS values than the Clearfil Repair system among all tested materials except for the InCoris TZI group (p<0.05). Conclusion All groups, except for the InCoris TZI group, repaired with iGOS Repair system showed higher μSBS than Clearfil Repair. The type of restoration and repair material is important in the success of the fracture repair.
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Orrell, Catherine, Rochelle P. Walensky, Elena Losina, Jennifer Pitt, Kenneth A. Freedberg et Robin Wood. « HIV type-1 clade C resistance genotypes in treatment-naive patients and after first virological failure in a large community antiretroviral therapy programme ». Antiviral Therapy 14, no 4 (mai 2009) : 523–31. http://dx.doi.org/10.1177/135965350901400414.
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Background This study aimed to evaluate HIV type-1 (HIV-1) drug resistance pretreatment and in those failing first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy (ART) in South Africa. Methods This was an observational cohort. Genotypic resistance testing was performed on treatment-naive individuals and those failing first-line ART (confirmed HIV-1 RNA>1,000 copies/ml) from public sector clinics in Cape Town (2002–2007). Resistance profiles and mutations relative to timing of known virological failure were examined. Results In total, 230 patients (120 treatment-naive and 110 with virological failure) were included: 98% had clade C virus. Among treatment-naive patients, prevalence of primary resistance was 2.5% (95% confidence interval 0.0–5.3). Three patients had one significant reverse transcriptase mutation: K65R, Y181C and G190A. Among treatment-experienced patients, 95 (86%) individuals had therapy-limiting NNRTI mutations, including K103N (55%), V106M (31%) and Y181C (9%). The M184V mutation was the most common mutation, found in 86 (78%) patients. In total, 10 (9%) patients had the K65R mutation. More individuals tended to develop thymidine analogue mutations when sampling occurred after 6 months of detected therapy failure (10/31 [32%] individuals) compared with those who had genotyping before 6 months (15/79 [19%] patients; P=0.246). Conclusions Prevalence of primary resistance in a sample of ART-naive clade C HIV-1-infected individuals in South Africa was low during the study period. Patients failing first-line ART most often developed resistance to NNRTIs and nucleoside reverse transcriptase inhibitors, the two drug classes used in first-line therapy. Viral load monitoring in this setting is crucial and individual genotypes in those failing first-line therapy should be considered.
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Yaakoby-Rotem, Sarit, et Ronny Geva. « Asymmetric Attention Networks : The Case of Children ». Journal of the International Neuropsychological Society 20, no 4 (11 mars 2014) : 434–43. http://dx.doi.org/10.1017/s1355617714000150.
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AbstractVisuospatial attention-networks are represented in both hemispheres, with right-hemisphere dominance in adults. Little is known about the lateralization of the attentional-networks in children. To assess the lateralization of attentional-networks in children aged 5 years, performance on a Lateralized-Attention-Network-Test specifically designed for children (LANT-C) was compared with performance on the Attention-Network-Test for children (ANT-C). Participants were 82 children, aged 5–6 years (55% boys, middle–class, mainstream schooling). They were examined with both the ANT-C and the LANT-C along with evaluation of intelligence and attention questionnaires. Multiple analysis of variance showed a main effect for network, with high efficiency for orienting and lower executive efficiency (accuracy; p < .001; η2 = .282). An effect for procedure, elucidated higher efficiency in the ANT-C relatively to the LANT-C (accuracy; p < .01; η2 = .097). A procedure × network interaction effect was also found, showing that this procedure difference is present in the alerting and executive networks (accuracy; p < .05; η2 = .096). LANT-C analysis showed a left visual-field advantage in alerting, (accuracy; p < .05; η2 = .066), while executing with the right hand benefitted executive performance (response-time; p < .05; η2 = .06). Results extend previous findings manifesting a right-hemisphere advantage in children's alerting-attention, pointing to the importance of lateralization of brain function to the understanding of the integrity of attention-networks in children. (JINS, 2014, 20, 1–10)
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Gardner, Viv. « Philip C. Kolin Shakespeare and Feminist Criticism : an Annotated Bibliography and CommentaryNew York : Garland, 1991. 420 p. £55. ISBN 0-82240-87386-X. » New Theatre Quarterly 8, no 31 (août 1992) : 291. http://dx.doi.org/10.1017/s0266464x00006928.
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Lapshina, Z. S. « ARCHEOLOGY OF THE LOWER AMUR RIVER : TO THE STUDY OF THE SUKPAI ARTISTIC STYLE AMONG THE PETROGLYPHS OF THE AMUR AND USSURI ». History : facts and symbols, no 2 (9 juin 2022) : 46–55. http://dx.doi.org/10.24888/2410-4205-2022-31-2-47-55.
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Among the hundreds of archaeological sites in the lower reaches of the Amur basin, a special place belongs to the stones and rocks with ancient drawings. The rock art of the Lower Amur region has been studied since the sixties of the nineteenth century. Among the discoverers and researchers are the names of local historians and scientists. Systematic academic scientific research of petroglyphs monuments was carried out only 100 years later, in the sixties of the twentieth century, by Soviet archaeologists. The research source base (topography, description, tracing, scientific interpretation and publication of materials) was prepared by a team of employees of the Far Eastern Archaeological Expedition of the Institute of Archeology and Ethnography of the Siberian Branch of the USSR Academy of Sciences under the leadership of A. P. Okladnikov. Pisanitsa on the Sukpai River in the Ussuri River basin is one of the new sites of rock art in the region, it was discovered in the 1980s by archaeologist V. I. Dyakov, an employee of the Institute of History, Archeology and Ethnography of the Peoples of the Far East of the Far Eastern Branch of the Russian Academy of Sciences. The article offers the experience of studying the stylistic diversity of the Lower Amur rock art monuments, namely, the drawings of the Sukpai petroglyph, which predetermines its relevance. The novelty of the study is due to the fact that the article highlights the signs of the Sukpai artistic style, the extent of its distribution among the petroglyphs of the region and adjacent territories. To write the work, a wide range of research methods was used, including the method of analyzing scientific literature, the sources were scientific papers on the topic of the study. The result of the research: a) the distinctive features of the style of plots on the rock of the Sukpai River are highlighted; b) similar images were traced on the stones and rocks of the Sikachi-Alyan-Malyshevo site; c) substantiation of the identification of the Sukpai artistic style among the petroglyphs of the Lower Amur; d) the similarity of the drawings of the sukpai style with the plots of the shamanic thematic direction of the rock art monuments of the adjacent territories of Eastern Siberia, Yakutia, the Upper and Middle Amur Region, and Transbaikalia was traced.
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Noritake, Hidenao, Yoshimasa Kobayashi, Yukimasa Ooba, Kensuke Kitsugi, Shin Shimoyama, Satoru Yamazaki, Takeshi Chida, Shinya Watanabe, Kazuhito Kawata et Takafumi Suda. « Improved Serum Alpha-Fetoprotein Levels after Iron Reduction Therapy in HCV Patients ». ISRN Hepatology 2014 (10 février 2014) : 1–7. http://dx.doi.org/10.1155/2014/875140.
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Background and Aims. To examine the changes in serum alpha-fetoprotein (AFP) levels after iron reduction by therapeutic phlebotomy in chronic hepatitis C patients. Methods. This retrospective study included 26 chronic hepatitis C patients. The patients were developed iron depletion by repeated therapeutic phlebotomies. Results. Iron reduction therapy significantly reduced the median level of serum AFP from 13 to 7 ng/mL, ALT from 96 to 50 IU/L, gamma-glutamyl transpeptidase (GGT) from 55 to 28 IU/L, and ferritin from 191 to 10 ng/mL (P<0.001 for each). The rate of decline in the AFP level correlated positively only with that in GGT (r=0.695, P=0.001), although a spurious correlation was observed between the rates of decline for AFP and ALT. The AFP level normalized (<10 ng/mL) posttreatment in eight (50%) of 16 patients who had elevated pretreatment AFP levels. Normalized post-treatment ALT and GGT levels were seen in 12% (3 of 26) and 39% (7 of 18) of the patients, respectively. Multivariate analysis identified a post-treatment GGT level of <30 IU/L as an independent factor associated with post-treatment AFP normalization (odds ratio, 21; 95% confidence interval, 1.5–293; P=0.024). Conclusions. Iron reduction by therapeutic phlebotomy can reduce serum AFP and GGT levels in chronic hepatitis C patients.
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Martins, Vitor F., Jessica R. Dent, Kristoffer Svensson, Shahriar Tahvilian, Maedha Begur, Shivani Lakkaraju, Elisa H. Buckner et al. « Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity ». American Journal of Physiology-Endocrinology and Metabolism 316, no 6 (1 juin 2019) : E1024—E1035. http://dx.doi.org/10.1152/ajpendo.00497.2018.
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Akt is a critical mediator of insulin-stimulated glucose uptake in skeletal muscle. The acetyltransferases, E1A binding protein p300 (p300) and cAMP response element-binding protein binding protein (CBP) are phosphorylated and activated by Akt, and p300/CBP can acetylate and inactivate Akt, thus giving rise to a possible Akt-p300/CBP axis. Our objective was to determine the importance of p300 and CBP to skeletal muscle insulin sensitivity. We used Cre-LoxP methodology to generate mice with germline [muscle creatine kinase promoter (P-MCK and C-MCK)] or inducible [tamoxifen-activated, human skeletal actin promoter (P-iHSA and C-iHSA)] knockout of p300 or CBP. A subset of P-MCK and C-MCK mice were switched to a calorie-restriction diet (60% of ad libitum intake) or high-fat diet at 10 wk of age. For P-iHSA and C-iHSA mice, knockout was induced at 10 wk of age. At 13–15 wk of age, we measured whole-body energy expenditure, oral glucose tolerance, and/or ex vivo skeletal muscle insulin sensitivity. Although p300 and CBP protein abundance and mRNA expression were reduced 55%–90% in p300 and CBP knockout mice, there were no genotype differences in energy expenditure or fasting glucose and insulin concentrations. Moreover, neither loss of p300 or CBP impacted oral glucose tolerance or skeletal muscle insulin sensitivity, nor did their loss impact alterations in these parameters in response to a calorie restriction or high-fat diet. Muscle-specific loss of either p300 or CBP, be it germline or in adulthood, does not impact energy expenditure, glucose tolerance, or skeletal muscle insulin action.
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Glotov, Andrey S., Oleg S. Glotov, Mikhail V. Moskalenko, Viktor A. Rogozkin, Tatyana E. Ivashchenko et Vladislav S. Baranov. « Analysis of genes polymorphisms of renin-angiotensine systems in population, athletes and elderly people ». Ecological genetics 2, no 4 (15 décembre 2004) : 40–43. http://dx.doi.org/10.17816/ecogen2440-43.
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We analyzed AGT (M235T), ACE (I/D), AGTR1 (A1166C) genes polymorphisms of renin-angiotensine systems in population, athletes and elderly people by PCR/RFLP methods. It was shown increasing of M/T genotype of AGT gene in rowers compared with population group (46 and 34%, accordantly), I/D of ACE (55 and 48%, accordantly) and decreasing of A/C genotype of AGTR1 gene (38 and 51%). It was detected significantly increasing of M/T genotype of AGT gene elderly people compared with population group (56 and 34%, accordantly, x2=l 1,828, p=0,0006). The received data allow to make the assumption of a possible role renin-angiotensine systems in process of ageing and active physical working capacitу
Thèses sur le sujet "Art. 55 c.p"
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ROSSI, LUCREZIA SILVANA. « LA LEGITTIMA DIFESA NEL DOMICILIO (ART. 52 C. 2-4 C.P.) UN¿INDAGINE TRA STORIA, COMPARAZIONE, TEORIA E PRASSI ». Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/852006.
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L’elaborato tratta il delicato tema della legittima difesa esercitata nel domicilio, che è stato oggetto di due riforme negli ultimi quindici anni – prima nel 2006, poi nel 2019 –, suscitando diffuse critiche e contrastanti pareri in ordine alla sua esatta portata.
La grande attenzione pubblica per l’istituto e i due interventi legislativi hanno stimolato l’interesse e il desiderio di approfondire l’origine, la ratio e l’evoluzione della scriminante di cui all’art. 52 c.p. Lo scopo della presente indagine è duplice: da una parte, si è cercato di comprendere le esigenze sottostanti alle riforme e, più in generale, il fondamento del bisogno così ben radicato nella società contemporanea di una differenziazione di trattamento per le aggressioni perpetrate all’interno dell’abitazione; dall’altra, invece, partendo dallo studio della disciplina attualmente in vigore e dell’applicazione concreta della medesima ad opera della giurisprudenza, si è provato a trovare un equilibrio più soddisfacente tra le esigenze diffuse e il rispetto della Carta costituzionale e della Convenzione europea dei diritti dell’uomo, in sintesi una “contro-riforma sostenibile”.
La tesi si articola in tre parti, di cui la prima è dedicata all’analisi storico-comparatistica della causa di giustificazione. In particolare, lo studio ripercorre le origini dell’istituto a partire dal diritto romano sino ai giorni nostri, cercando di evidenziare i precedenti storici atti a spiegare l’attuale predisposizione di una figura speciale di legittima difesa a beneficio di colui che sia aggredito in luoghi privati in ordine ai quali vanti uno ius excludendi alios nei confronti dell’aggressore. La ricerca storica è affiancata da un’indagine comparatistica, anch’essa impostata in prospettiva storica, che allarga lo sguardo alle scelte compiute in argomento dai principali ordinamenti europei – segnatamente quello francese e inglese –, nonché dal sistema federale statunitense.
La seconda parte della tesi ha ad oggetto il diritto interno vigente; in particolare l’elaborato affronta prima la legge n. 59 del 13 febbraio 2006 e poi la legge n. 36 del 26 aprile 2019, ossia le riforme che hanno conferito rilievo alla figura speciale della legittima difesa domiciliare. A tal fine, si considera tanto il contesto politico criminale che ne ha segnato l’origine, quanto il contenuto delle riforme alla luce della giurisprudenza di legittimità; è stato infatti svolto uno studio su tutte le pronunce emesse dalla Corte di Cassazione in materia di legittima difesa domiciliare dal 1° gennaio 2000 sino al 1° gennaio 2021. Grazie a tale ricerca è emerso da una parte come la prima riforma risulti sostanzialmente priva di ricadute concrete e, dall’altra, come il secondo intervento legislativo, ove non sottoposto a un’interpretazione correttiva alla luce delle direttrici costituzionali e convenzionali europee, sia pericoloso per la tenuta del sistema. Lungo tale direttrice, l’indagine si sofferma in particolare sul ruolo che dovrebbero assumere il requisito della necessità e le presunzioni normative di legittimità della reazione. Con riferimento al caso dell’eccesso, poi, si prospettano i criteri rilevatori del grave turbamento e delle condizioni di minorata difesa a cui si ricollegano effetti scusanti.
La terza ed ultima parte dell’elaborato, infine, tratta l’istituto in una prospettiva de iure condendo; nello specifico, prendendo le mosse dai risultati raggiunti attraverso l’indagine realizzata, si è provato ad avanzare una proposta di risistemazione della causa di giustificazione che si articola in tre passaggi, idealmente collegati tra loro. Secondo tale ipotesi di lavoro, l’art. 52 c.p. guadagnerebbe in razionalità ed efficacia se, anzitutto, fossero eliminati i commi disciplinanti la legittima difesa domiciliare attualmente in vigore; inoltre, alla disposizione di cui al c. 1 dell’art. 52 c.p. dovrebbe affiancarsi una scusante legata allo stato di turbamento emotivo vissuto dall’aggredito, applicabile alla fattispecie generale per i casi di eccesso e di errore sulla legittima difesa; infine, si potrebbe prevedere una presunzione iuris tantum di pericolo attuale per la sola incolumità dei presenti in caso di aggressione perpetrata all’interno del domicilio e dell’esercizio commerciale.
La compresenza di tali proposte modificative sembrerebbe in grado di conferire un rinnovato equilibrio alla causa di giustificazione, da una parte dando voce e riconoscimento alle istanze diffuse, dall’altra rispettando i principi e i valori di cui la Costituzione e la Convezione europea dei diritti dell’uomo sono espressione, dall’altra ancora imprimendo una spinta contraria rispetto all’attuale tendenza antistatalista, se non addirittura anticostituzionale, di cui le due recenti riforme in materia si sono rese portavoce.The thesis deals with the delicate issue of self defence exercised in the home, which has been the subject of two reforms in the last fifteen years – first in 2006, then in 2019 –, arousing widespread criticism and conflicting opinions regarding its exact scope. The great public attention for the institute and the two legislative interventions have stimulated the interest and the desire to investigate the origin, the ratio and the evolution of the justification regulated by art. 52 c.p. The purpose of this survey is twofold: on the one hand, an attempt has been made to understand the needs underlying the reforms and, more generally, the foundation of the need so well rooted in contemporary society for a differentiation of treatment for attacks perpetrated inside the house; on the other hand, starting from the study of the discipline currently in force and the concrete application of the same by jurisprudence, an attempt has been made to find a more satisfactory balance between the widespread needs and compliance with the Constitutional Charter and the European Convention of human rights, in short a "sustainable counter-reform". The thesis is divided into three parts, of which the first is dedicated to the historical-comparative analysis of the justification. In particular, the study traces the origins of the institute starting from Roman law up to the present day, trying to highlight the historical precedents capable of explaining the current predisposition of a special figure of self defence in favour of anyone who is attacked in private places, where individuals boasts an ius excludendi alios against the aggressor. The historical research is accompanied by a comparative survey, also set in a historical perspective, which broadens the gaze to the choices made on the subject by the main European systems – notably the French and English ones –, as well as by the US federal system. The second part of the thesis concerns the internal law in force; in particular, the paper first deals with law no. 59 of 13 February 2006 and then the law n. 36 of 26 April 2019, i.e. the reforms that have given prominence to the special figure of home self defence. To this end, both the criminal political context that marked its origin and the content of the reforms in the light of the jurisprudence of legitimacy are considered; in fact, a study was carried out on all the rulings issued by the Court of Cassation regarding home self defence from 1 January 2000 until 1 January 2021. Thanks to this research, it emerged on the one hand how the first reform is substantially devoid of concrete repercussions and, on the other hand, how the second legislative intervention, if not subjected to a corrective interpretation in the light of constitutional and conventional guidelines, is dangerous for system tightness. Along this line, the investigation focuses in particular on the role that the requirement of necessity and the normative presumptions of legitimacy of the reaction should assume. With reference to the case of excess, then, are presented the criteria for detecting the serious disturbance and the conditions of impaired defence to which excuse effects are linked. Finally, the third and last part of the paper deals with the institution from a de iure condendo perspective; specifically, starting from the results achieved through the survey carried out, an attempt was made to put forward a proposal for reorganization of the justification which is divided into three steps, ideally connected to each other. According to this working hypothesis, art. 52 c.p. would gain rationality and effectiveness if, first of all, the paragraphs governing home self defence currently in force were eliminated; furthermore, beside the provision referred to art. 52 c. 1 c.p., there should be an excuse linked to the state of emotional disturbance experienced by the attacked, applicable in cases of excess and error in self defence; finally, an iuris tantum presumption of current danger could be envisaged for the sole safety of those present in the event of aggression perpetrated within the home and business. The coexistence of these amending proposals would seem capable of giving a renewed balance to the justification, first of all giving voice and recognition to the widespread requests, furthermore respecting the principles and values of which the Constitution and the European Convention of human rights are an expression, and lastly still giving a push contrary to the current anti-statist tendency, if not even anti-constitutional, of which the two recent reforms on the subject have become spokesmen.
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Oliveira, Rejane Nunes Lopes de. « Tratamento restaurador atraum?tico (ART) : avalia??o de um protocolo de atendimento em gestantes da rede p?blica do munic?pio de Feira de Santana ». UNIVERSIDADE ESTADUAL DE FEIRA DE SANTANA, 2007. http://localhost:8080/tede/handle/tede/40.
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Previous issue date: 2007-12-18The Atraumatic Restorative Treatment (ART) is a treatment alternative for the caries disease, which remains with high prevalence, and constitutes a serious public health problem. The ART consists in the removal of the carious tissue with manual instruments and later closing of its cavities with glass-ionomer cement (GIC). It is important to develop a health promotion program associated with the clinical procedure. The World Health Organization (WHO) recommends the utilization of such technique for several groups, including pregnant women. The aim of this clinical essay was to check the use of the Atraumatic Restorative Treatment in pregnant women of the public system in Feira de Santana Bahia. The sample consisted of 35 pregnant women who underwent 84 class-I restorations and 71 dental sealants with GIC Ketac Molar EasyMix. After anamnesis and clinical examinations, a semi-structured form was filled out on oral hygiene and dietary practices, and on the extent of the technical acceptance. This group was inserted into a health promotion program with speeches, supervised brushings and plaque rate collection. An examiner carried out clinical evaluation of the restorations and of the sealants after a six-month period, through standard scores (0-9) which were later turned into success (0, 1 and 7) and unsuccess (2, 3, 4, 5, 6 and 8). It has been used the successful criterion for the sealants (present or partial loss) and the unsuccessful one (total loss). After the systematization of the collected data, it was observed success in 90,5% for ART and 85,9% for sealants. With regard to the program, 71,4% pregnant women reported changes in oral hygiene and 54,3% in dietary habits. A significant difference occurred between the initial and final averages of the plaque rates, being such reduction, on average, 17,71%. The extent of technical acceptance was 100%. It has been concluded that ART is feasible as a tooth decay treatment alternative in pregnant women inserted in a preventive educational program. It has been inferred that more researches have to be carried out, promoting the development of public policies which increase the use of ART in pregnant women.
A c?rie dent?ria constitui-se em um grave problema de sa?de p?blica, com alta preval?ncia em diversas popula??es. O Tratamento Restaurador Atraum?tico (ART) ? uma alternativa de interven??o para esta patologia, consiste na remo??o do tecido cariado com instrumentos manuais e posterior fechamento das cavidades com cimento de ion?mero de vidro (CIV). Aliado ao procedimento cl?nico, ? importante se desenvolver um programa de promo??o de sa?de. A Organiza??o Mundial de Sa?de (OMS) recomenda a utiliza??o do ART para diversos grupos, entre eles, as gestantes. Este ensaio cl?nico teve como objetivo avaliar um protocolo de Tratamento Restaurador Atraum?tico em gestantes da rede p?blica de Feira de Santana - BA. A amostra consistiu de 35 gestantes, nas quais foram realizados 84 restaura??es e 71 selantes com CIV Ketac Molar Easymix. Ap?s anamnese e exame cl?nico, foi aplicado um formul?rio semi-estruturado sobre as pr?ticas de higiene bucal e dieta, e sobre o grau de aceita??o da t?cnica. Esse grupo foi inserido em um programa educativo-preventivo de sa?de, com palestras, escova??o supervisionada e coleta de ?ndice de placa. Ap?s seis meses, a avalia??o cl?nica das restaura??es e dos selantes foi realizada por um examinador. As restaura??es foram analisadas pelos escores padronizados (0-9) que posteriormente foram transformados em sucesso (0, 1 e 7) e insucesso (2, 3, 4, 5, 6 e 8). Para os selantes utilizou-se o crit?rio sucesso (presente ou perda parcial) e insucesso (perda total). Ap?s a sistematiza??o dos dados coletados observou-se sucesso de 90,5% para ART e 85,9% para selantes. Em rela??o ao programa, 71,4% das gestantes referiu mudan?as de h?bitos na higiene bucal e 54,3% mudaram h?bitos na dieta. Ocorreu uma diferen?a significativa entre as m?dias dos ?ndices de placa inicial e final, sendo essa redu??o em m?dia de 17,71%. O grau de aceita??o da t?cnica foi de 100%. Concluiu-se que o ART ? uma alternativa de tratamento vi?vel para c?rie em gestantes, inseridas em um programa educativo preventivo. Este estudo aponta para a necessidade de mais pesquisas que fomentem o desenvolvimento de pol?ticas p?blicas e ampliem a utiliza??o do ART em gestantes.
Livres sur le sujet "Art. 55 c.p"
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Rodríguez, Joshua Merchán. C. T. P. : Compañía de Trueque Polimérico. Ciudad de México : PotentA Ediciones, 2021.
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Kelly, Ellsworth. Ellsworth Kelly : Seven paintings, 1952-55 (1987). Boston, Mass : Museum of Fine Arts, Boston, 1987.
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D, Bartlett Louisa, et Sewell C. Biggs Museum of American Art., dir. Delaware silver : The Col. Kenneth P. and Regina I. Brown collection. Dover, DE : Biggs Museum of American Art, 2008.
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(Firm), Drouot-Richelieu. Tableaux modernes : P. Aizpiri, A. Barbier, E.C. Benezit, E. Bourdin, M. Boulet, Y. Brayer, G. Cambier, Carlos-Reymond, J. Carzou, P. Charavel, V. Charreton, H.C. Delpy, A. Dignimont, J. Dunoyer, A. Dunoyer de Segonzac, G. d'Espagnat, S. Ferat, L. Fini, Frank-Boggs, L. Genin, M. Girard, N. Giuffrida, H. Goetz, A. Guillaumin, A. Hambourg, N. Henon, C. Hilaire, J.B. Jongkind, M. Journod, L. Laborit, P. Laprade, P. Laroche, M. Laurencin, E. de La Villeon, H. Lebasque, A. Lhote, J. Le Guennec, M. Luce, D. Lucas, E. Maclet, H. Manguin, A. Marquet, M. Martin, Mayeux, Meg, P.E. Montezin, J.P. Pascin, R. Quence, L. Touchagues, J.B. Valadie, L. Valtat, Vander Hacehenn, M. de Vlaminck, C. Wauthier, F. Witte, F. Ziem ; tableaux du XIXe siècle ; bijoux ; argenterie ; verrerie "art nouveau" et modernes ; Extrême-Orient, paravants, vases, pagode en serpentine, statuette en jade ; sculptures ; meubles et objets d'art, commode transition par E. Avril, pair de fauteuils par I. Nadal, bibliothèque par P. Defriche, Bureau par P. Sormani, tapis. Paris : Drouot-Richelieu, 2001.
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(Firm), Drouot-Richelieu. Gravures XVIIIe et XIXe siècles ... dessins, tableaux modernes XIXe et XXe siècles ... dessins, tableaux anciens XVIIe et XVIIIe siècles ... curiosités ... éperonnerie, étriers et mors ... objets d'art et d'ameublement ... art nouveau ... beau mobilier d'époque et de style ... bel ensemble de meubles néo renaissance ... tapis, tapisserie : G. Volpato, G.B. Piranesi, F. Goya, P.C. Helleu, J. Benoit-Levy, Y. Brayer, R. Cat, C. Cottet, E. Galien-Laloue, Gen Paul, C. Guys, H. Harpignies, J. Girardet, R. His, E. de la Villeon, A. Lebourg, P.E. Montezin, C. Pissaro, Th. Clément, L. Icart, F. Mortelmans, A. Veron, C.N. Cochin, H. Robert, A. Romany, nombreux portraits de l'École française XVIIIe, N.D. Bouget, G.P. Verbruggen II Le Jeune, J.P. George-Juillard ; bel enxemble de couteaux provenant de la collection Léon Lindet ; bronzes de Barys, pendules, cartel d'applique écaille, vases de E. Gallé, mobilier de salle à manger de Majorelle (expo. Paris 1904) ; belle commode de P. Roussel, paire d'encoignures de J. Holthausen, important tapis d'Aubusson XIXe siècle, tapisserie de Lille d'après Téniers. Paris : Néret-Minet, 2002.
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Farrell, K. Art and Nature X6 C/P. Little, Brown Book Group Limited, 1992.
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Kravchuk, Michael. C. P. e Bach Solfeggietto : Practice Guide. Independently Published, 2020.
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C. Itoh F10-55 P/R Printer/Book (Sams Computerfacts). Sams, 1987.
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Barredo, Maria, Caleb Fernandez, Seth Fernandez, Eliott Garcia et Robert Cruz. Art of Story : P. A. C. E. 2018-19. Independently Published, 2019.
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Harold, Wayne Alan, et P. Craig Russell. P Craig Russell Selfish & Other Stories Fine Art Hc (C : 0-1-. Wayne Alan Harold Productions, 2019.
Trouver le texte intégralChapitres de livres sur le sujet "Art. 55 c.p"
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Desille, Amandine, et Karolina Nikielska-Sekula. « Introduction ». Dans IMISCOE Research Series, 1–27. Cham : Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-67608-7_1.
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AbstractA significant effort in theorising and conceptualising the visual has been made within various disciplines. To mention only a few, Howard Becker (Art as collective action. Am Sociol Rev 767–776, 1974) in visual sociology, Lucien Taylor (Visualising theory. Routledge, 1994), Marcus Banks and Howard Morphy ((eds): Rethinking visual anthropology. Yale University Press, London, 1999) and Jay Ruby (Picturing culture: explorations of film and anthropology. University of Chicago Press, Chicago, 2000) in visual anthropology, Chris Jenk ((ed): Visual culture. Routledge, 1995) in cultural studies, Gillian Rose (Visual methodologies: an introduction to the interpretation of visual methods. Sage, 2001) in geography and Sarah Pink (Doing visual ethnography. Sage, London, 2001) in visual ethnography, all produced fundamental works focusing on the visual in social sciences. This book, however, without diminishing the disciplinary work within the subject, proposes to approach visual methodologies in the specific context of a field of study, adopting an interdisciplinary approach that brings together geography, sociology, anthropology and communication studies. As Adrian Favell (Rebooting migration theory: interdisciplinarity, globality and postdisciplinarity in migration studies. In: Brettell C, Hollifield J (eds) Migration theory: talking across disciplines. Routledge, pp 259–278, 2007, p. 1988) has suggested: “On the face of it, there could hardly be a topic in the contemporary social sciences more naturally ripe for interdisciplinary thinking than migration studies.” In this piece we will attempt to explain why the adoption of visual methodologies in the field of migration studies is of particular interest.
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Treggiari, Susan. « The Iuniae (?c.75–49) ». Dans Servilia and her Family, 131–44. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198829348.003.0007.
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Servilia is likely to have taken the lead in arranging her daughters’ marriages, all of which were distinguished. One Iunia was married ?c.61 to the much older P. Servilius Isauricus, cos. 48, 41; they had a son, Publius (c.55–AD 35) cos. 25, and a presumed daughter, who married her first cousin, M. Lepidus, and died, like him, in 30. Another Iunia was married (?late 60s/early 50s) to M. Aemilius Lepidus; they had two sons, Marcus and Quintus. She was still alive in 30. The other daughter (died AD 22) married C. Cassius pr. 44. His parents are unknown. If he had no prior wife, Iunia probably married him by 59 and bore a son (known to have become adult 15 March 44) c.58. In 49–48 Cassius was a Pompeian admiral, but Caesar forgave him. He was a man of warmth and charm.
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Ramos, Jaciara Andrade, Karina Ferrazzoli Devienne Vicentine et Afonso Pelli. « The effect of noise pollution on animal welfare - a case study in balb/c mice ». Dans COLLECTION OF INTERNATIONAL TOPICS IN HEALTH SCIENCE- V1. Seven Editora, 2023. http://dx.doi.org/10.56238/colleinternhealthscienv1-083.
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The quality of life is determined primarily by the quality of the environment. Many variables act on the environment, including noise pollution, present in everyday life. According to the World Health Organization, above 55 db, the body begins to suffer the impact of noise, causing mild stress and excitement. One of the main responses is activation of the hypothalamic-pituitary-adrenal axis, causing the release of glucocorticoids. These hormones act on the energy metabolism, increasing the amount of free fatty acids in the bloodstream. Thus, changes in lipid metabolism have been reported after stressful situations. In this experiment we used Mus musculus balb/c mice submitted to chronic sound stress, at 90dB, for 30 days, at night, from 8 pm to 2 am the next day. The animals were euthanized by decapitation after anesthesia, and the blood collected was used to measure cholesterol, triglycerides, and glucose. During the experiment the animals' weight was monitored, and there was no considerable variation between the control and experimental groups. Regarding the biochemical parameters, there were statistically significant differences in the levels of cholesterol, triglycerides, and glucose. The significance levels, or p values, were 0.067 (p less than 6.7%); 0.053 (p less than 5.3%), and 0.000 (p less than 0.0009%), respectively. With the present study, it can be concluded that stress hormones interfere with cholesterol, triglyceride and glucose metabolism. The chronic noise stress model can be considered a good environmental stress model that mimics urban stress.
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« ΘΑΛΑΣΣΑ ΤΟΥ ΠΡΩΪΟΥ ». Dans C. P. Cavafy, 108–9. Princeton University Press, 2022. http://dx.doi.org/10.2307/j.ctv25wxchr.55.
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Taber, Douglass F. « Organocatalyzed C–C Ring Construction : The Bradshaw/Bonjoch Synthesis of (−)-Cermizine B ». Dans Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0071.
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In a continuation of his studies (OHL20141229, OHL20140811) of organocatalyzed 2+2 photocycloaddition, Thorsten Bach of the Technische Universität München assembled (Angew. Chem. Int. Ed. 2014, 53, 7661) 3 by adding 2 to 1. Li-Xin Wang of the Chengdu Institute of Organic Chemistry also used (Org. Lett. 2014, 16, 6436) an organocatalyst to effect the addition of 5 to 4 to give 6. Shuichi Nakamura of the Nagoya Institute of Technology devised (Org. Lett. 2014, 16, 4452) an organocatalyst that mediated the enantioselective opening of the aziridine 7 to 8. Zhi Li of the National University of Singapore cloned (Chem. Commun. 2014, 50, 9729) an enzyme from Acinetobacter sp. RS1 that reduced 9 to 10. Gregory C. Fu of Caltech developed (Angew. Chem. Int. Ed. 2014, 53, 13183) a phosphine catalyst that directed the addition of 12 to 11 to give 13. Armido Studer of the Westfälische Wilhelms-Universität Münster showed (Angew. Chem. Int. Ed. 2014, 53, 9622) that 15 could be added to 14 to give 16 in high ee. Akkattu T. Biju of CSIR-National Chemical Laboratory described (Chem. Commun. 2014, 50, 14539) related results. The photostimulated enantioselective ketone alkylation developed (Chem. Sci. 2014, 5, 2438) by Paolo Melchiorre of ICIQ was powerful enough to enable the alkylation of 17 with 18 to give 19, overcoming the stereoelectronic preference for axial bond formation. David W. Lupton of Monash University established (J. Am. Chem. Soc. 2014, 136, 14397) the organocatalyzed transformation of the dienyl ester 20 to 21. James McNulty of McMaster University added (Angew. Chem. Int. Ed. 2014, 53, 8450) azido acetone 23 to 22 to give 24 in high ee. There are sixteen enantiomerically-pure diastereomers of the product 27. John C.-G. Zhao of the University of Texas at San Antonio showed (Angew. Chem. Int. Ed. 2014, 53, 7619) that with the proper choice of organocatalyst, with or without subsequent epimerization, it was possible to selectively prepare any one of eight of those diastereomers by the addition of 26 to 25. William P. Malachowski of Bryn Mawr College showed (Tetrahedron Lett. 2014, 55, 4616) that 28, readily prepared by a Birch reduction protocol, was converted by heating followed by exposure to catalytic Me3P to the angularly-substituted octalone 29.
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Bailey, Matthew P., et Joan T. Hallett. « Ice Crystals in Cirrus ». Dans Cirrus. Oxford University Press, 2002. http://dx.doi.org/10.1093/oso/9780195130720.003.0007.
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Cirrus is conventionally considered as cloud forming in the Earth's upper troposphere at temperatures somewhat below -40°C, composed of ice crystals and forming long, wispy trails. This characteristic shape, in the form of a curl of hair, results from evaporation in vertical shear of horizontal winds, and leads to its Latin name—originally proposed by Luke Howard in 1803. Here we address the nucleation, growth, and evaporation processes that influence the concentration and shape of individual particles and their role in specific atmospheric phenomena. To set the scene, figure 3.1 shows examples of such crystals collected by aircraft. In this chapter, we also address the radiation and dynamic environment in which crystals grow and subsequently evaporate. Crystal growth depends on the location of a crystal with respect to the cloud edge and the intervening cloud optical thickness; evaporation depends on larger scale processes as at fronts and cumulonimbus anvils and also at inversion interfaces where shear instability and resulting gravity waves produce significant effects over a range of scales. These effects lead to differing cloud radiative properties and ultimately control of the earth's radiation budget and overall climate (Liou 1986; Stephens et al. 1990; Liou and Takano 1994; Takano and Liou 1995; Mishchenko et al. 1996; Strauss et al. 1997; Macke et al. 1998). A growing crystal implies a supersaturated or supercooled environment with respect to the solid phase and can, in general, be considered as growth from either three-fold symmetry overlying a needle, (NASA DC-8,TOGA COARE,-48°C, deep tropical convection, 1993). The replica visually shows a uniformity of color in vertical illumination, indicating a thin crystal a few micrometers thick, uniform to ±0.05 μm. e. Replica of needles, small scalene and triangular three-fold symmetry plates, hexagonal plates, columns, and irregular crystals collected by D.L.R. Falcon in thin cirrus over the Alps, temperature -55°C, October 29,1992. (Courtesy Dr. P. Wendling.) f. Replica of crystals from the evaporating tip of a contrail formed 50 s earlier by the NASA 757 aircraft sampled from the NASA DC-8. Multiple trigonal symmetry crystals are present, with a 60° rotation (left side), along with hexagonal and scalene and triangle crystals, concentration 10/cm3. Clear sky environment over Kansas, temperature -52°C, 1840-1900Z, 4 May 1996.
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« CONVENIOS DE ASOCIACIÓN (ART.355 C. P. ) ». Dans Manual de Contratación de la Administración pública 4 ed. Reforma de la ley 80 de 1993. Incluye Decreto 1082 de 2015, 1073–100. Universidad del Externado de Colombia, 2005. http://dx.doi.org/10.2307/j.ctv1503j96.11.
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« for a fixed p. An affine transformation yields : A(L(x, y)) = L(ax+by+c, dx+ey+ f) = sp(ax+by+c). = get sp(ax ». Dans Algorithmic and Computational Robotics, 367–72. A K Peters/CRC Press, 2001. http://dx.doi.org/10.1201/9781439864135-55.
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Petty, Wayne. « C. P. E. Bach and the fine art of transposition ». Dans Schenker Studies 2, 49–66. Cambridge University Press, 1999. http://dx.doi.org/10.1017/cbo9780511470295.006.
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Straus, Joseph N. « Aaron Copland, Piano Variations, Theme (1930) ». Dans The Art of Post-Tonal Analysis, 33–38. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780197543979.003.0008.
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In this theme, the process of variation with respect to a four-note motto—E-C-D♯-C♯—is continuous. The theme moves through different collectional environments (octatonic and pentatonic) and engages triadic transformations (L, P, R, SLIDE, and HEXPOLE). Ultimately, it can be thought of in relation to the tonality of C♯ minor, but not in any traditional way.
Actes de conférences sur le sujet "Art. 55 c.p"
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Sugimori, Daisuke, Kiyoto Kajiyama, Shunsuke Kawashima et Yuho Matsumoto. « Phosphatidylglycerol-specific Phospholipase C from Amycolatopsis Sp. NT115 : Biochemical Characterization and Heterologous Expression ». Dans 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/fmmj5845.
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In recent years, phosphatidylglycerol (PG) has been attracting attention in the field of cell physiology such as photosynthesis and germ cells, or clinical diagnosis. Most of phospholipids containing PG are analyzed using HPLC and LC-MS; however, it has been desired to develop an enzymatic assay method for determination of PG concentration in a simple, easy, and high-through put.In our presentation, biochemical characterization of a PG-specific phospholipase C (PG-PLC) from Amycolatopsis sp. NT115 will be reported. PG-PLC (molecular mass, 55 kDa) showed maximal activity at pH 6.0 and 55°C. PG-PLC showed almost no activity on other diacylphospholipids, dipalmitoylPG, lysoPG and glycerol 3-phosphate, demonstrating PG-PLC can recognize not only the substrate headgroup but also the acyl chains. PG-PLC was inhibited by Zn2+; however, it was hardly inhibited by EDTA and non-ionic surfactants such as Triton X-100, Tween 80, Briji 35 and Nonidet P-40. PG-PLC activity was enhanced by 1 mM Mn2+, Al3+, 0.1% sodium deoxycholate by 1.3-2.5 folds. Recombinant PG-PLC (rPG-PLC) was extracellularly produced using Streptomyces lividans/pUC702 expression system. However, unexpectedly it was produced with the N-terminal region deleted by ca. 230 amino acids. As a result, the stability of the deletion mutant (Δ230aa) was markedly decreased. In 96 h culture, rPG-PLC with His6-tag was produced with 0.188 U/mL and 3.36×10-2 U/mg-protein in the culture supernatant. Moreover, 1.52 mg-protein of the purified Δ220aa (2.5 U/mL, 16.4 U/mg-protein) was yielded from 0.9 L of the culture supernatant by His-tag affinity chromatography. Using the purified Δ220aa, kinetic parameters were determined to be Km=0.368 mM, 99.2 µM/min (6.51 mmol/min/mg-protein), kcat=5.29×10-2 s-1, kcat/Km=0.256 mM-1s-1 for POPG.
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Saha, Bidyut B., Ibrahim I. El-Sharkawy, Anutosh Chakraborty, Shigeru Koyama et Kim Choon Ng. « Study on Single- and Multi-Stage Adsorption Cooling Cycles Working at Sub and Above Atmospheric Conditions ». Dans ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-68616.
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This study deals with the performance analysis of single- and multi-stage adsorption cooling cycles working at partial vacuum and pressurized conditions for cooling applications. Four adsorbent-refrigerant pairs namely activated carbon fiber-ethanol, silica gel-water, Maxsorb II-R134a and Fluka-R134a pairs have been investigated. The former two pairs are deemed to be suitable for adsorption cycles working at pressures ranging from 1 to 11 kPa while the latter two are suitable for those working at above atmospheric pressure conditions typically between about 0.3 and 0.8 MPa. Invoking the adsorption isotherms of the assorted pairs, the pressure-temperature-concentration (P-T-W) diagrams have been presented. Pertaining a thermodynamic framework, the performance of both single- and multi-stage cycles in terms of specific cooling effect (SCE) and coefficient of performance (COP) has also been studied. Theoretical results show that the former two pairs i.e., the adsorption cycles working at partial vacuum pressures are suitable for surface cooling while latter two are suitable for micro cooling applications. Moreover, the multi-stage adsorption cycles can be operational at a heat source temperature below about 55°C, a region that could not be reached by any conventional adsorption cycle.
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Doherty, Margaret. « P-28 The art of dying well ». Dans Leading, Learning and Innovating, Hospice UK 2017 National Conference, 22–24 November 2017, Liverpool. British Medical Journal Publishing Group, 2017. http://dx.doi.org/10.1136/bmjspcare-2017-hospice.55.
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Baumgardner, Marc E., et Daniel B. Olsen. « Poison Build-up and Performance Degradation of an Oxidation Catalyst in 2-Stroke Natural Gas Engine Exhaust ». Dans ASME 2017 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/icef2017-3550.
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Due to current and future exhaust emissions regulations, oxidation catalysts are increasingly being added to the exhaust streams of large-bore, 2-stroke, natural gas engines. Such catalysts have been found to have a limited operational lifetime, primarily due to chemical (i.e. catalyst poisoning) and mechanical fouling resulting from the carry-over of lubrication oil from the cylinders. It is critical for users and catalyst developers to understand the nature and rate of catalyst deactivation under these circumstances. This study examines the degradation of an exhaust oxidation catalyst on a large-bore, 2-stroke, lean-burn, natural gas field engine over the course of 2 years. Specifically this work examines the process by which the catalyst was aged and tested and presents a timeline of catalyst degradation under commercially relevant circumstances. The catalyst was aged in the field for 2 month intervals in the exhaust slipstream of a GMVH-12 engine and intermittently brought back to the Colorado State Engines and Energy Conversion Laboratory for both engine testing and catalyst surface analysis. Engine testing consisted of measuring catalyst reduction efficiency as a function of temperature as well as the determination of the light-off temperature for several exhaust components. The catalyst surface was analyzed via SEM/EDS and XPS techniques to examine the location and rate of poison deposition. After 2 years on-line the catalyst light-off temperature had increased ∼55°F (31°C) and ∼34 wt% poisons (S, P, Zn) were built up on the catalyst surface, both of which represent significant catalyst deactivation.
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Camiz, Alessandro. « Diachronic transformations of urban routes for the theory of attractors ». Dans 24th ISUF 2017 - City and Territory in the Globalization Age. Valencia : Universitat Politècnica València, 2017. http://dx.doi.org/10.4995/isuf2017.2017.5639.
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Alessandro Camiz ¹ ¹ Department of Architecture, Girne American University, Cyprus, Association for Historical Dialogue and Research, Home for Cooperation (H4C), 28 Marcou Dracou Street, Nicosia, Cyprus, 1102. E-mail: alessandrocamiz@gau.edu.tr Keywords (3-5): urban tissues, urban morphology, urban routes, theory, history Conference topics and scale: Tools of analysis in urban morphology Recent urban morphology studies consider urban tissues as living organisms changing in time (Strappa, Carlotti, Camiz, 2016), following this assumption the theory should examine more analytically what Muratori called ‘medievalisation’ (Muratori, 1959), a term describing some of the transformations of urban routes happened in the middle ages. The paper considers the diachronic deformation of routes, and other multi-scalar occurrences of the attraction phenomena (Charalambous, Geddes, 2015), introducing the notion of attractors and repellers. Archaeological studies already do consider attractors and repellers as a tool to interpret some territorial transformations, following the assumption that “the trajectory that a system follows through time is the result of a continuous dynamic interaction between that system and the multiple 'attractors' in its environment” (Renfrew, Bahn, 2013, p. 184). There are different elements that can act as attractors in an urban environment, such as bridges, city walls, city gates, water systems, markets, special buildings, and it is possible to consider each of these anthropic attractors as equivalent to a morphological attractor at the geographical scale. We can even interpret the ridge-top theory (Caniggia, 1976) as the result of attraction and repellence of geographic features on anthropic routes. The territorial scale analysis is the methodological base of the theory, but the attractors herein considered operate at the urban scale, deviating locally across time from a rectilinear trajectory and defining a specific urban fabric. The research interprets and reads the effects of attractors on urban routes and fabrics as a method for the reconstruction of Nicosia’s medieval city walls, in continuity between the Conzenian approach (Whitehand, 2012) and the Italian School of Urban Morphology (Marzot, 2002). References:, Muratori, S. (1959) Studi per un’operante storia urbana di Venezia (Istituto Poligrafico dello Stato, Roma). Caniggia, G. (1976) Strutture dello spazio antropico. Studi e note (Uniedit, Firenze). Marzot, N. (2002) ‘The study of urban form in Italy’, Urban Morphology 6.2, 59-73. Whitehand, J.W.R. (2012) ‘Issues in urban morphology’, Urban Morphology 16.1, 55-65. Renfrew, C., Bahn, P. (eds.) (2013) Archaeology: The Key Concepts, (London, Routledge). Charalambous, N., Geddes, I. (2015) ‘Making Spatial Sense of Historical Social Data’, Journal of Space Syntax 6.1, 81-101. Strappa, G., Carlotti, P., Camiz, A. (2016) Urban Morphology and Historical Fabrics. Contemporary design of small towns in Latium (Gangemi, Roma).
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Jaramillo, Valeria, Elizabeth J. Catlos, Elizabeth Bell, Daniel F. Stockli, Axel K. Schmitt, Emily J. Chin et An Yin. « SUPERPOSITION OF 80-55 MA HIGH P-T (0.7 GPA/750 °C) METAMORPHISM BY MID-TERTIARY DETACHMENT FAULTING IN THE WHIPPLE MOUNTAINS, SE CALIFORNIA ». Dans GSA Connects 2022 meeting in Denver, Colorado. Geological Society of America, 2022. http://dx.doi.org/10.1130/abs/2022am-378171.
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Osbert, Ashaba, Samson Rwahwire et Yvonne Tusiimire. « Re-Engineering Plastic Waste for the Modification of Bitumen Blends ». Dans International Conference on Advances in Materials Science 2021. Switzerland : Trans Tech Publications Ltd, 2022. http://dx.doi.org/10.4028/p-31t6r8.
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The increase in the production and utilization of plastics has created a never-ending problem of plastic waste. Developing countries face challenges with plastic waste disposal that in due process negatively impacts the environmental ecosystem. That notwithstanding, it suffices to mention that most developing countries have poor road networks that pose a burden towards smooth economic and social development. The problem is further exacerbated by the limited availability of bitumen which is usually imported but also has environmental concerns. It is against this background that we proposed alternative binders from plastic waste which can help developing countries to manage plastic waste as well as build road networks, thereby leading to sustainable development. We explored the 80/100 penetration grade bitumen modification (Penetration grade 85 and Softening temperature 46°C) using polyethylene terephthalate (PET) waste (2 – 12%) and lignin (0.2%) as a crosslinking agent by weight for every PET waste – Bitumen sample. The research showed that Plastic waste and lignin improved the performance of bitumen. The modified bitumen with 10% waste PET and 0.2% lignin enhanced the softening point and penetration points to 55°C and 46, respectively; hence the incorporation of PET and lignin provided better properties compared to the neat bitumen.
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Gu, Haiming, Xinyu Li, S. G. Lu, Minren Lin, Xiaoshi Qian, J. P. Cheng, Q. M. Zhang, Ailan Cheng et Brent Craven. « Compact Cooling Devices Based on Giant Electrocaloric Effect Dielectrics ». Dans ASME 2012 Heat Transfer Summer Conference collocated with the ASME 2012 Fluids Engineering Division Summer Meeting and the ASME 2012 10th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/ht2012-58128.
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The electrocaloric effect (ECE) refers to the change in temperature and/or entropy of a dielectric material due to the electric field induced change of dipolar states. Giant ECE is discovered in P(VDF-TrFE) ferroelectric copolymers near ferroelectric-paraelectric (F-P) transition temperature which is normally much higher than room temperature. This paper presents the two defect-inducing methods to lower and broaden working temperature range of P(VDF-TrFE) based copolymers for ECE, and thus make it preferable for practical cooling device. Giant ECE is experimentally demonstrated in large temperature range (0–55°C). In addition, an electrocaloric oscillatory refrigerator (ECOR) was proposed and simulated by finite volume method and its high performance was theoretically demonstrated. Temperature gradient larger than 30 °C can be maintained across the two sides of a 1 cm device. For ΔT = 20 °C cooling condition, a high cooling power (5.4 W/cm2) and significantly higher coefficient of performance (COP) can be achieved (50% of Carnot efficiency).
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Kucuk, Ezgi, et Ayşe Sema Kubat. « Rethinking Urban Design Problems through Morphological Regions : Case of Beyazıt Square ». Dans 24th ISUF 2017 - City and Territory in the Globalization Age. Valencia : Universitat Politècnica València, 2017. http://dx.doi.org/10.4995/isuf2017.2017.6179.
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Rethinking Urban Design Problems through Morphological Regions Ezgi Küçük¹, Ayşe Sema Kubat² ¹Urban Planning Coordinator, Marmara Municipalities Union ²Prof., Dr., Istanbul Technical Univercity, Faculty of Architecture, Department of City and Regional Planning E-mail: ezgikucuk89@gmail.com, kubat@itu.edu.tr Keywords: the Historical Peninsula, morphological regions, urban blocks, urban design, Beyazıt Square Conference topics and scale: Urban form and social use of space The concept of urban square is a debated issue in the context of urban design practices in Islamic cities. Recognizing the relation between urban morphology and urban design studies in city planning and urban design practices is highly vital. Beyazıt Square, which is the center of the city of Istanbul, could not be integrated to the other parts of the city either configurationally or socially although many design projects have been previously planned and discussed. In this study, the Historical Peninsula of Istanbul is observed as an essential unit of the traditional path reflecting each civilization, namely Roman, Byzantium, Ottoman and Republic of Turkey that have been settled in the region. Transformations in urban blocks in Beyazıt region are elaborated through a series of morphological analyses based on the Conzenian approach of urban morphology. Morphological regions of the Historical Peninsula are identified and Beyazıt region is addressed in detail in terms of the transformations in urban block components, that are; street, plot and buildings. The effects of surrounding units which are the mosque, university buildings, booksellers and Grandbazaar on Beyazıt Square are discussed according to the morphological analyses that are applied to the region. Previous design practices and the existing plan of the area are observed through the analyses including town plan, building block, and land use and ownership patterns. It is revealed that existing design problems in Beyazıt Square come from the absence of urban morphological analyses in all planning and design practices. Through morphological regions as well as the conservation plans, urban design projects can be reconsidered. References Baş, Y. (2010) ‘Production of Urbanism as the Reproduction of Property Relations: Morphologenesis of Yenişehir-Ankara’, PhD thesis, Middle East Technical University. Barret, H.J. (1996) ‘Townscape changes and local planning management in city conservation areas: the example of Birmingham and Bristol’, PhD thesis, University of Birmingham. Bienstman, H. (2007) ‘Morphological Concepts and Landscape Management: The Cases of Alkmaar and Bromsgrove’, PhD thesis, University of Birmingham. Conzen, M.R.G. (1960) Alnwick Northumberland: a study in town-plan analysis, Institute of British Geographers, London. Conzen, M.R.G. (2004) Thinking About Urban Form: papers on urban morphology 1932-1998, Peter Lang, Bern. Çelik, Z. (1993) The Remaking of Istanbul: Portrait of an Ottoman City in the Nineteenth Century, University of California Press, Berkeley. Günay, B. (1999) Property Relations and Urban Space, METU Faculty of Architecture Press, Ankara. Kubat, A.S. (1999) ‘The morphological history of Istanbul’, Urban Morphology 3.1, 28-41. Noziet, H. (2008) ‘Fabrique urbaine: a new concept in urban history and morphology’, Urban Morphology, 13.1, 55-56. Panerai, P., Castex, J., Depaule, J. C. and Samuels, I. (2004) Urban Forms: The Death and Life of the Urban Block, Architectural Press, Oxford. Tekeli, İ. (2010) Türkiye’nin Kent Planlama ve Kent Araştırmaları Tarihi Yazıları, (Articles of Turkey’s History of Urban Planning and Urban Studies), Tarih Vakfı Yurt Yayınları, Istanbul. Whitehand, J.W.R. (2001) ‘British urban morphology: the Conzenian tradition’, Urban Morphology 5.2, 3-10. Whitehand, J.W.R. (2009) ‘The structure of urban landscapes: strengthening research and practice’, Urban Morphology 13.1, 5-22.
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García De Diego, Beatriz Oda Plasencia, Samuel Leopoldo Romero Guillena et Francisco Gotor Sanchez-Luengo. « Trastorno depresivo mayor y Trastorno por consumo de sustancias. Uso de vortioxetina (Serie de Casos) ». Dans 22° Congreso de la Sociedad Española de Patología Dual (SEPD) 2020. SEPD, 2020. http://dx.doi.org/10.17579/sepd2020p139.
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Objetivo: Evaluar la eficacia y tolerabilidad del tratamiento con Vortioxetina en el trastorno depresivo mayor en comorbilidad con trastorno por consumo de sustancias. Metodología: 18 pacientes, de entre 21-55 años, diagnosticados de trastorno depresivo mayor y trastorno por consumo de sustancias (6 por consumo de alcohol, 6 por consumo de cannabis y 6 por consumo de cocaína) (criterios diagnósticos DSM-5) que inician tratamiento con Vortioxetina. Evaluación basal, a los 1, 3 y 6 meses de las siguientes escales y variables: a)Inventario de depresión de Beck, b) Cambio del consumo de sustancias durante el tiempo de seguimiento, evaluado a través del Timeline Follow-Back (TLFB) y c) Auto-reporte de efectos secundarios. Resultados: - Escala de Depresión de Beck: reducción estadísticamente significativa en la puntuación media, 21,67 (±3,36) en la visita basal, 5,21 (±4,76) a los 6 meses (Δ=16,47±5,23; p<0,01). Siendo independiente de la sustancia de consumo. - Reducción en el consumo de sustancias al final de estudio: A) Alcohol: Media basal de 100,53 g/día (± 59,28), a 25,3 g/día (± 21,46) (Δ=75,23 ±37,97; p<0,01), B) Cannabis, media balsa de 4, 99 g/día (± 2,22) a 2,4 g/día (± 1,47) (Δ=3,52 ± 1,51; p<0,05) y C) Cocaína, de 2,55 g/día de media (± 3,56) en la visita basal, a una media de 1,89/día (± 3,22) en la visita final. (Δ=0,66 ± 2,89). La reducción estadísticamente significativa para alcohol y cannabis. Tolerabilidad: La tasa de continuidad del tratamiento fue de un 66,66% y el efecto adversos mas frecuente fueron las náuseas 44,4% Conclusión: En esta serie de casos, vortioxetina resulta eficaz y bien tolerado como parte del abordaje integral del paciente con trastorno depresivo mayor y trastorno por consumo de sustancias.
Rapports d'organisations sur le sujet "Art. 55 c.p"
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Tschirhart, V. Keating correlation coefficient results over the Tehery Lake area, Nunavut, NTS 56-B and parts of 55-N, O, P, 56-A, C, F, G and H. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2017. http://dx.doi.org/10.4095/299252.
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Rankin, Nicole, Deborah McGregor, Candice Donnelly, Bethany Van Dort, Richard De Abreu Lourenco, Anne Cust et Emily Stone. Lung cancer screening using low-dose computed tomography for high risk populations : Investigating effectiveness and screening program implementation considerations : An Evidence Check rapid review brokered by the Sax Institute (www.saxinstitute.org.au) for the Cancer Institute NSW. The Sax Institute, octobre 2019. http://dx.doi.org/10.57022/clzt5093.
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Background Lung cancer is the number one cause of cancer death worldwide.(1) It is the fifth most commonly diagnosed cancer in Australia (12,741 cases diagnosed in 2018) and the leading cause of cancer death.(2) The number of years of potential life lost to lung cancer in Australia is estimated to be 58,450, similar to that of colorectal and breast cancer combined.(3) While tobacco control strategies are most effective for disease prevention in the general population, early detection via low dose computed tomography (LDCT) screening in high-risk populations is a viable option for detecting asymptomatic disease in current (13%) and former (24%) Australian smokers.(4) The purpose of this Evidence Check review is to identify and analyse existing and emerging evidence for LDCT lung cancer screening in high-risk individuals to guide future program and policy planning. Evidence Check questions This review aimed to address the following questions: 1. What is the evidence for the effectiveness of lung cancer screening for higher-risk individuals? 2. What is the evidence of potential harms from lung cancer screening for higher-risk individuals? 3. What are the main components of recent major lung cancer screening programs or trials? 4. What is the cost-effectiveness of lung cancer screening programs (include studies of cost–utility)? Summary of methods The authors searched the peer-reviewed literature across three databases (MEDLINE, PsycINFO and Embase) for existing systematic reviews and original studies published between 1 January 2009 and 8 August 2019. Fifteen systematic reviews (of which 8 were contemporary) and 64 original publications met the inclusion criteria set across the four questions. Key findings Question 1: What is the evidence for the effectiveness of lung cancer screening for higher-risk individuals? There is sufficient evidence from systematic reviews and meta-analyses of combined (pooled) data from screening trials (of high-risk individuals) to indicate that LDCT examination is clinically effective in reducing lung cancer mortality. In 2011, the landmark National Lung Cancer Screening Trial (NLST, a large-scale randomised controlled trial [RCT] conducted in the US) reported a 20% (95% CI 6.8% – 26.7%; P=0.004) relative reduction in mortality among long-term heavy smokers over three rounds of annual screening. High-risk eligibility criteria was defined as people aged 55–74 years with a smoking history of ≥30 pack-years (years in which a smoker has consumed 20-plus cigarettes each day) and, for former smokers, ≥30 pack-years and have quit within the past 15 years.(5) All-cause mortality was reduced by 6.7% (95% CI, 1.2% – 13.6%; P=0.02). Initial data from the second landmark RCT, the NEderlands-Leuvens Longkanker Screenings ONderzoek (known as the NELSON trial), have found an even greater reduction of 26% (95% CI, 9% – 41%) in lung cancer mortality, with full trial results yet to be published.(6, 7) Pooled analyses, including several smaller-scale European LDCT screening trials insufficiently powered in their own right, collectively demonstrate a statistically significant reduction in lung cancer mortality (RR 0.82, 95% CI 0.73–0.91).(8) Despite the reduction in all-cause mortality found in the NLST, pooled analyses of seven trials found no statistically significant difference in all-cause mortality (RR 0.95, 95% CI 0.90–1.00).(8) However, cancer-specific mortality is currently the most relevant outcome in cancer screening trials. These seven trials demonstrated a significantly greater proportion of early stage cancers in LDCT groups compared with controls (RR 2.08, 95% CI 1.43–3.03). Thus, when considering results across mortality outcomes and early stage cancers diagnosed, LDCT screening is considered to be clinically effective. Question 2: What is the evidence of potential harms from lung cancer screening for higher-risk individuals? The harms of LDCT lung cancer screening include false positive tests and the consequences of unnecessary invasive follow-up procedures for conditions that are eventually diagnosed as benign. While LDCT screening leads to an increased frequency of invasive procedures, it does not result in greater mortality soon after an invasive procedure (in trial settings when compared with the control arm).(8) Overdiagnosis, exposure to radiation, psychological distress and an impact on quality of life are other known harms. Systematic review evidence indicates the benefits of LDCT screening are likely to outweigh the harms. The potential harms are likely to be reduced as refinements are made to LDCT screening protocols through: i) the application of risk predication models (e.g. the PLCOm2012), which enable a more accurate selection of the high-risk population through the use of specific criteria (beyond age and smoking history); ii) the use of nodule management algorithms (e.g. Lung-RADS, PanCan), which assist in the diagnostic evaluation of screen-detected nodules and cancers (e.g. more precise volumetric assessment of nodules); and, iii) more judicious selection of patients for invasive procedures. Recent evidence suggests a positive LDCT result may transiently increase psychological distress but does not have long-term adverse effects on psychological distress or health-related quality of life (HRQoL). With regards to smoking cessation, there is no evidence to suggest screening participation invokes a false sense of assurance in smokers, nor a reduction in motivation to quit. The NELSON and Danish trials found no difference in smoking cessation rates between LDCT screening and control groups. Higher net cessation rates, compared with general population, suggest those who participate in screening trials may already be motivated to quit. Question 3: What are the main components of recent major lung cancer screening programs or trials? There are no systematic reviews that capture the main components of recent major lung cancer screening trials and programs. We extracted evidence from original studies and clinical guidance documents and organised this into key groups to form a concise set of components for potential implementation of a national lung cancer screening program in Australia: 1. Identifying the high-risk population: recruitment, eligibility, selection and referral 2. Educating the public, people at high risk and healthcare providers; this includes creating awareness of lung cancer, the benefits and harms of LDCT screening, and shared decision-making 3. Components necessary for health services to deliver a screening program: a. Planning phase: e.g. human resources to coordinate the program, electronic data systems that integrate medical records information and link to an established national registry b. Implementation phase: e.g. human and technological resources required to conduct LDCT examinations, interpretation of reports and communication of results to participants c. Monitoring and evaluation phase: e.g. monitoring outcomes across patients, radiological reporting, compliance with established standards and a quality assurance program 4. Data reporting and research, e.g. audit and feedback to multidisciplinary teams, reporting outcomes to enhance international research into LDCT screening 5. Incorporation of smoking cessation interventions, e.g. specific programs designed for LDCT screening or referral to existing community or hospital-based services that deliver cessation interventions. Most original studies are single-institution evaluations that contain descriptive data about the processes required to establish and implement a high-risk population-based screening program. Across all studies there is a consistent message as to the challenges and complexities of establishing LDCT screening programs to attract people at high risk who will receive the greatest benefits from participation. With regards to smoking cessation, evidence from one systematic review indicates the optimal strategy for incorporating smoking cessation interventions into a LDCT screening program is unclear. There is widespread agreement that LDCT screening attendance presents a ‘teachable moment’ for cessation advice, especially among those people who receive a positive scan result. Smoking cessation is an area of significant research investment; for instance, eight US-based clinical trials are now underway that aim to address how best to design and deliver cessation programs within large-scale LDCT screening programs.(9) Question 4: What is the cost-effectiveness of lung cancer screening programs (include studies of cost–utility)? Assessing the value or cost-effectiveness of LDCT screening involves a complex interplay of factors including data on effectiveness and costs, and institutional context. A key input is data about the effectiveness of potential and current screening programs with respect to case detection, and the likely outcomes of treating those cases sooner (in the presence of LDCT screening) as opposed to later (in the absence of LDCT screening). Evidence about the cost-effectiveness of LDCT screening programs has been summarised in two systematic reviews. We identified a further 13 studies—five modelling studies, one discrete choice experiment and seven articles—that used a variety of methods to assess cost-effectiveness. Three modelling studies indicated LDCT screening was cost-effective in the settings of the US and Europe. Two studies—one from Australia and one from New Zealand—reported LDCT screening would not be cost-effective using NLST-like protocols. We anticipate that, following the full publication of the NELSON trial, cost-effectiveness studies will likely be updated with new data that reduce uncertainty about factors that influence modelling outcomes, including the findings of indeterminate nodules. Gaps in the evidence There is a large and accessible body of evidence as to the effectiveness (Q1) and harms (Q2) of LDCT screening for lung cancer. Nevertheless, there are significant gaps in the evidence about the program components that are required to implement an effective LDCT screening program (Q3). Questions about LDCT screening acceptability and feasibility were not explicitly included in the scope. However, as the evidence is based primarily on US programs and UK pilot studies, the relevance to the local setting requires careful consideration. The Queensland Lung Cancer Screening Study provides feasibility data about clinical aspects of LDCT screening but little about program design. The International Lung Screening Trial is still in the recruitment phase and findings are not yet available for inclusion in this Evidence Check. The Australian Population Based Screening Framework was developed to “inform decision-makers on the key issues to be considered when assessing potential screening programs in Australia”.(10) As the Framework is specific to population-based, rather than high-risk, screening programs, there is a lack of clarity about transferability of criteria. However, the Framework criteria do stipulate that a screening program must be acceptable to “important subgroups such as target participants who are from culturally and linguistically diverse backgrounds, Aboriginal and Torres Strait Islander people, people from disadvantaged groups and people with a disability”.(10) An extensive search of the literature highlighted that there is very little information about the acceptability of LDCT screening to these population groups in Australia. Yet they are part of the high-risk population.(10) There are also considerable gaps in the evidence about the cost-effectiveness of LDCT screening in different settings, including Australia. The evidence base in this area is rapidly evolving and is likely to include new data from the NELSON trial and incorporate data about the costs of targeted- and immuno-therapies as these treatments become more widely available in Australia.