Bibliographies thématiques / Antibodies

Littérature scientifique sur le sujet « Antibodies »

Auteur : Grafiati
Publié le 4 juin 2021
Mis à jour le 7 juillet 2024

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Articles de revues sur le sujet "Antibodies"

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Deora, Kanika, et Ruchee Khanna. « Clinical Profile of the Patients with Antiphospholipid Antibodies : Lupus Anticoagulant and Anticardiolipin Antibodies ». Indian Journal of Forensic Medicine and Pathology 12, no 3 (2019) : 195–99. http://dx.doi.org/10.21088/ijfmp.0974.3383.12319.6.

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Chiswell, David J., et John McCaffery. « Phage antibodies : will new ‘coliclonal’ antibodies replace monoclonal antibodies ? » Trends in Biotechnology 10 (1992) : 80–84. http://dx.doi.org/10.1016/0167-7799(92)90178-x.

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Linhardt, Robert J., C. W. Abell, R. M. Denney, B. W. Altrock, R. Auerbach, S. D. Bernal, R. E. Canfield et al. « Monoclonal antibodies and immobilized antibodies ». Applied Biochemistry and Biotechnology 15, no 1 (juin 1987) : 53–80. http://dx.doi.org/10.1007/bf02798506.

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Favoreel, Herman W., Geert Van Minnebruggen, Gerlinde R. Van de Walle, Jolanta Ficinska et Hans J. Nauwynck. « Herpesvirus interference with virus-specific antibodies : Bridging antibodies, internalizing antibodies, and hiding from antibodies ». Veterinary Microbiology 113, no 3-4 (mars 2006) : 257–63. http://dx.doi.org/10.1016/j.vetmic.2005.11.003.

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Clark, A. « Antibodies ». Journal of Clinical Pathology 42, no 5 (1 mai 1989) : 559. http://dx.doi.org/10.1136/jcp.42.5.559-c.

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Bradbury, Andrew, Nileena Velappan, Vittorio Verzillo, Milan Ovecka, Leslie Chasteen, Daniele Sblattero, Roberto Marzari, Jianlong Lou, Robert Siegel et Peter Pavlik. « Antibodies in proteomics I : generating antibodies ». Trends in Biotechnology 21, no 6 (juin 2003) : 275–81. http://dx.doi.org/10.1016/s0167-7799(03)00112-4.

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Kounis, Nicholas G., George D. Soufras et George N. Kounis. « Antibodies against antibodies inducing Kounis syndrome ». International Journal of Cardiology 168, no 5 (octobre 2013) : 4804–5. http://dx.doi.org/10.1016/j.ijcard.2013.07.037.

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Trier, Nicole, Paul Hansen et Gunnar Houen. « Peptides, Antibodies, Peptide Antibodies and More ». International Journal of Molecular Sciences 20, no 24 (13 décembre 2019) : 6289. http://dx.doi.org/10.3390/ijms20246289.

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The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed to any desired target, which illustrates their versatile nature and broad spectrum of use as illustrated by numerous applications of peptide antibodies. In recent years, due to the inherent limitations such as size and physical properties of antibodies, it has been attempted to generate new molecular compounds with equally high specificity and affinity, albeit with relatively low success. Based on this, peptides, antibodies, and peptide antibodies have established their importance and remain crucial reagents in molecular biology.
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Shoenfeld, Yehuda. « The idiotypic network in autoimmunity : antibodies that bind antibodies that bind antibodies ». Nature Medicine 10, no 1 (janvier 2004) : 17–18. http://dx.doi.org/10.1038/nm0104-17.

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Bobrovnik, S. A., M. O. Demchenko et S. V. Komisarenko. « Effect of trifluoroethanol on antibodies binding properties ». Ukrainian Biochemical Journal 95, no 1 (26 avril 2023) : 20–30. http://dx.doi.org/10.15407/ubj95.01.020.

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The studies on the influence of organic co-solvents on the structure and function of antibodies are of key interest, especially in view of antibodies broad use as recognizing elements in different analytical systems. Here we studied the effect of co-solvent 2,2,2-trifluoroethanol (TFE) on the ability of anti-ovalbumin monoclonal antibodies to interact with its specific antigen. Antibody affinity to antigen and the rate constants of antibody binding to immobilized antigen were analyzed. Changes in antibody reactivity with incubation time which depended on TFE concentration and temperature were revealed. When treatment of antibodies with TFE was carried out at 0°C, we observed nonlinear, non-monotonous changes of antibody reactivity with initial fast decrease and substantial increase that may be related to the loss of antigen binding reactivity by some part of antibodies at the start but its restoration when the incubation proceeds. Keywords: 2;2;2-trifluoroethanol, antibody affinity, antigen-antibody interaction, monoclonal antibodies, ovalbumin
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Thèses sur le sujet "Antibodies"

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Ng, King Man. « Anti-neurofascin antibodies ». Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-150730.

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Austin, Eric B. « Human monoclonal antibodies ». Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276187.

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Evans, Rachael Yvonne. « The production of anti-idiotopic antibodies to monoclonal anti-RhD antibodies ». Thesis, Lancaster University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274194.

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Kang, Sun-ah. « Apoptotic Cells, Anti-Phospholipid Antibodies, and Anti-Chromatin Antibodies in Autoimmunity ». Diss., Temple University Libraries, 2008. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/15651.

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Microbiology and Immunology
Ph.D.
Antiphospholipid antibodies (APAs) are detected in various autoimmune diseases, such as antiphospholipid syndrome (APS) and systemic lupus erythematosus. In addition to their binding to negatively charged phospholipids, APAs often cross-react with other molecules. Their potential biological effects are not fully understood. Apoptotic cells are a potential source of auto-antigens during systemic autoimmunity. Inefficient clearance of apoptotic cells results in the development of autoimmune manifestations and intracellular antigens such as nucleosomes become accessible during apoptosis. We examined a panel of monoclonal APAs generated from NZW/BXSB F1, a strain which spontaneously develops autoimmune symptoms reminiscent of APS. These APAs did not bind to live cells, but reacted strongly with different structures within apoptotic cells. Further analysis with various inhibitors indicated that the binding of APAs to apoptotic cells depends on specific caspase activities and on the modification of auto-antigens by reactive oxygen species (ROS). Therefore, apoptotic cells provide a potential source of APA antigens that may not be limited to phospholipids. Our data also indicate that physical accessibility and apoptosis-specific modification of auto-antigens by caspases or ROS are crucial factors for APA-antigen interactions. Various auto-antibodies such as APAs and anti-chromatin antibodies are pathogenic outcome of chronic autoimmune diseases. Their binding to auto-antigens, presumably exposed on apoptotic cells, elicits subsequent amplification of inflammatory responses, thus worsening disease progression. However, the precise immunological functions of auto-antibodies and the mechanism behind are not fully comprehended yet. We investigated immune responses generated by four different auto-immune complexes (auto-ICs) composed of auto-antibodies and apoptotic cells. In the presence of TLR ligation, the presence of auto-antibodies in auto-ICs amplified immune responses generated by apoptotic cells. In most cases, almost all the auto-ICs tested suppressed IL12, TNFa, while increasing IL10 production from macrophages. Further studies with various anti-Fc?R antibodies implied the essential role of various Fc?Rs in elevation of IL10 by auto-ICs. Studies with Mer-/- macrophages indicated that Mer is also crucial in auto-IC mediated augmentation of IL10 production. However, Mer was dispensable for the suppression of IL12. Taken together, auto-antibodies, by forming immune complexes with apoptotic cells, perform strong immunomodulatory functions. Particular importance is in the role of Fc?Rs and Mer in anti-inflammatory responses generated by auto-ICs. Paradoxical, but indispensible contribution of TLR ligation, especially TLR4, in anti-inflammatory responses generated by auto-ICs suggests that auto-antibodies may work as another layer of defense against endogenous danger signals.
Temple University--Theses
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Chmura, A. J. « Rational engineering of antibodies with irreversible binding : antibodies with infinite affinity / ». Connect to Digital dissertations. Restricted to UC campuses. Access is free to UC campus dissertations, 2001. http://uclibs.org/PID/11984.

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Thesis (Ph. D.)--University of California, Davis, 2002.
Degree granted in Chemistry. Dissertation completed in 2001; degree granted in 2002. Also available via the World Wide Web. (Restricted to UC campuses).
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Rada-Briega, Cristina. « Somatic hypermutation of antibodies ». Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318450.

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Plumpton, Christopher. « Monoclonal antibodies against phytochrome ». Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358677.

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Bentall, Andrew John. « Antibodies in kidney transplantation ». Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5817/.

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The aim of this thesis is to examine the effect of anti-donor antibodies in the clinical management and outcomes of antibody incompatible kidney transplantation. Initial studies were conducted to improve measurement of anti-ABO specific blood group antibodies. The specificity of antibody binding to blood group antigens (BGA) depended upon the assay platform and the nature of the core structure to which the BGA was bound. A standardised haemagglutination assay had excellent reproducibility, which was then applied to the analysis of samples derived from a study of 100 ABO incompatible kidney transplantation (ABOiKTx) in the UK where good clinical outcomes were achieved but there was wide variation reported in local assays quantifying BGA specific antibodies, without survival differences. In a highly sensitised HLA incompatible kidney transplant recipients (HLAiKTx), I demonstrated long term outcomes were poor compared to a compatible cohort, in particular with pre-formed donor specific anti-HLA Class II antibodies, in which histological injury of antibody damage occurred significantly earlier than with Class I antibodies. Further studies demonstrated that anti-HLA antibodies were associated with an inflammatory phenotype, but anti-donor ABO specific antibodies did not despite the activation of complement. Thus, inhibiting terminal complement activation, whilst reducing early antibody-mediated rejection did not abrogate all inflammation which was associated with the presence of IgM DSA. Reproducible and standardised assays are needed for antibody assessment in order to make good clinical decisions to improve patient outcomes. Further studies are needed to stop production or block mechanisms of ongoing cellular infiltrate to improve patient outcomes.
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Alcocer, Marcos J. C. « Wheat peptides and antibodies ». Thesis, University of East Anglia, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306066.

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Farzad, Zohreh (Emami Aleagha). « Studies on anti-tetanus antibodies ». Thesis, University of Edinburgh, 1985. http://hdl.handle.net/1842/23886.

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Livres sur le sujet "Antibodies"

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Szentivanyi, Andor, Paul H. Maurer et Bernard W. Janicki, dir. Antibodies. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6.

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Subramanian, G., dir. Antibodies. Boston, MA : Springer US, 2004. http://dx.doi.org/10.1007/978-1-4419-8875-1.

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Subramanian, G., dir. Antibodies. Boston, MA : Springer US, 2004. http://dx.doi.org/10.1007/978-1-4419-8877-5.

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Finch, Peter. Antibodies. Exeter, Devon : Stride Publications, 1997.

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Skal, David J. Antibodies. New York : Congdon & Weed, 1988.

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Anderson, Kevin J. Antibodies. New York : HarperPrism, 1998.

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Anderson, Kevin J. Antibodies. London : HarperCollins, 1997.

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1935-, Subramanian G., dir. Antibodies. New York : Kluwer Academic/Plenum Publishers, 2004.

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1935-, Subramanian G., dir. Antibodies. New York : Kluwer Academic/Plenum Publishers, 2004.

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Sashe, Alexandra. Antibodies. Bristol : Shearsman Books, 2013.

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Chapitres de livres sur le sujet "Antibodies"

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Dorrington, Keith J., et Michel H. Klein. « The Three-Dimensional Structure of Immunoglobulin G and its Relationship to the Expression of Biological Functions ». Dans Antibodies, 3–10. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_1.

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Siskind, Gregory W., Edmond A. Goidl, Young Tai Kim, Marc E. Weksler et G. Jeanette Thorbecke. « Anti-Hapten Idiotype Models in Studies of Aging and Idiotype Networks ». Dans Antibodies, 107–15. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_10.

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Erlanger, B. F., W. L. Cleveland, N. H. Wasserman, H. H. Ku, B. L. Hill, R. Sarangarajan, R. Rajagopalan et al. « Antibodies to Acetylcholine, Adenosine and Glucocorticoid Receptors by an Auto-Anti-Idiotypic Route ». Dans Antibodies, 119–34. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_11.

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Geha, Raif S. « Idiotypic Interactions in the Treatment of Human Diseases ». Dans Antibodies, 135–53. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_12.

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Talal, Norman. « Regulation of Autoimmune Diseases ». Dans Antibodies, 155–63. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_13.

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Morrison, Sherie L., Letitia A. Wims, Polly D. Gregor, Barry J. Kobrin et Vernon T. Oi. « Transfectomas Provide Antibodies with Novel Structures and Functions ». Dans Antibodies, 167–78. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_14.

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Uhr, Jonathan W., R. Jerrold Fulton et Ellen S. Vitetta. « The Use of Ricin a Chain-Containing Immunotoxins to Kill Neoplastic B Cells ». Dans Antibodies, 179–87. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_15.

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Oldham, Robert K. « Monoclonal Antibodies and Immunoconjugates as Anti-Cancer Agents ». Dans Antibodies, 189–200. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_16.

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Siskind, Gregory W. « Overview and Comments ». Dans Antibodies, 203–6. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_17.

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Kohler, Heinz, et Thomas Kieber-Emmons. « New Concepts in Antibody Structure ». Dans Antibodies, 11–17. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1873-6_2.

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Actes de conférences sur le sujet "Antibodies"

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NERI, DARIO. « FROM INTACT ANTIBODIES TO ARMED ANTIBODIES ». Dans 23rd International Solvay Conference on Chemistry. WORLD SCIENTIFIC, 2014. http://dx.doi.org/10.1142/9789814603836_0036.

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Kiefel, V., S. Santoso et C. Mueller-Eckhardt. « ANALYSIS OF PLATELET REACTIVE ANTIBODIES USING MONOCLONAL ANTIBODIES ». Dans XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643929.

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The characterization of platelet reactive alloantibodies and autoantibodies is mandatory for the diagnosis of posttransfusion purpura, neonatal alloimmune thrombocytopenia, autoimmune thrombocytopenia and for the selection of platelet donors prior to platelet transfusions in immunized polytransfused patients. The platelet immunofluorescence test is suitable for the detection of platelet reactive antibodies. In many cases, however, mixtures containing different platelet reactive antibodies have to be dissected.In order to analyze these sera, we have developed a novel enzyme immunoassay based upon monoclonal antibody specific immobilization of platelet antigens (MAIPA). In brief, platelets are incubated simultaneously with the (human) serum to be investigated and a monoclonal (mouse) antibody directed against an epitope on the same platelet membrane glycoprotein (GP). Platelets are then washed and solubilized in TRIS buffered saline containing NP40. The lysed platelets are then pipetted into the wells of microtiter plates, coated with goat anti mouse IgG where mouse anti GP-complexes are immobilized. Human platelet reactive antibodies on the same GP are detected using enzyme labelled goat anti human IgG, IgM, or IgA, respectively. Using mab Gi5, mab FMC25, mab w6.32 directed against epitopes on the glycoprotein complex IIb/IIIa, glycoprotein Ib and HLA class I molecule, respectively, and a panel of typed platelet donors, even sera containing different platelet reactive antibodies are readily analyzed. Results of experiments with platelet specific alloantibodies (anti P1A1, anti P1A2 and anti Bak(a)), autoantibodies (against the GP Ilb/IIIa complex and GP Ib) and a drug dependent antibody show that this assay allows to discriminate all these different platelet reactive antibodies.
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Bundell, C., et P. Hollingsworth. « 359 Antinuclear antibodies in iu/ml predicts dsdna and ena antibodies ». Dans LUPUS 2017 & ACA 2017, (12th International Congress on SLE &, 7th Asian Congress on Autoimmunity). Lupus Foundation of America, 2017. http://dx.doi.org/10.1136/lupus-2017-000215.359.

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Zanlorenzi, Laís, Nelzi Ferreira de Queiroz Junior, Carlos Gomes Bezerra Sobrinh, Laura Vilas Boas, Renato Nishiara et Thelma Skare. « ANTINUCLEAR ANTIBODIES IN ENDOMETRIOSIS ». Dans SBR 2021 Congresso Brasileiro de Reumatologia. Sociedade Brasileira de Reumatologia, 2021. http://dx.doi.org/10.47660/cbr.2021.2009.

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ESHHAR, ZELIG. « GENETICALLY ENGINEERED THERAPEUTIC ANTIBODIES ». Dans International Seminar on Nuclear War and Planetary Emergencies 25th Session. Singapore : World Scientific Publishing Co. Pte. Ltd., 2001. http://dx.doi.org/10.1142/9789812797001_0062.

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SIROTA, PINKHAS, KLARA SCHILD, MICHAEL FIRER, NEOMI ZURGIL, YORAM BARAK, AVNER ELIZUR et HANOCH SLOR. « ANTI Sm ANTIBODIES IN SCHIZOPHRENIA ». Dans IX World Congress of Psychiatry. WORLD SCIENTIFIC, 1994. http://dx.doi.org/10.1142/9789814440912_0014.

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Ivanova, SM, GG Karpova, NV Bogachiova, TA Riazantctva et AI Speranskey. « THU0061 Ribosomal p protein antibodies ». Dans Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.905.

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Sun, Yanjie, Zhuoyun Wan et Zixiao Zhang. « Therapeutic Monoclonal Antibodies : Clinical Applications ». Dans International Conference on Biotechnology and Biomedicine. SCITEPRESS - Science and Technology Publications, 2022. http://dx.doi.org/10.5220/0012020800003633.

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Cucnik, Sasa. « SP0176 PATHOGENIC ANTIBODIES IN PHOSPHOLIPID SYNDROM ». Dans Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.8453.

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SIDHU, SACHDEV S. « FROM NATURAL ANTIBODIES TO SYNTHETIC PROTEINS ». Dans 23rd International Solvay Conference on Chemistry. WORLD SCIENTIFIC, 2014. http://dx.doi.org/10.1142/9789814603836_0035.

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Rapports d'organisations sur le sujet "Antibodies"

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Benkovic, Stephen J. Catalytic Antibodies. Fort Belvoir, VA : Defense Technical Information Center, mars 1992. http://dx.doi.org/10.21236/ada252019.

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Ivy, John M. Production of Anti-Ferret IgA Antibodies ; and production of monoclonal antibodies. Fort Belvoir, VA : Defense Technical Information Center, avril 1994. http://dx.doi.org/10.21236/ada279534.

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Bradley, David Sherman. Avian Diagnostic and Therapeutic Antibodies. Office of Scientific and Technical Information (OSTI), décembre 2012. http://dx.doi.org/10.2172/1114116.

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Snyder, Christopher M., et Lawrence J. Wysocki. Dissecting Immunogenicity of Monoclonal Antibodies. Fort Belvoir, VA : Defense Technical Information Center, juin 2002. http://dx.doi.org/10.21236/ada407659.

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Snyder, Christopher M., et Lawrence J. Wysocki. Dissecting Immunogenicity of Monoclonal Antibodies. Fort Belvoir, VA : Defense Technical Information Center, juin 2003. http://dx.doi.org/10.21236/ada417364.

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Jaszczak, R. J. SPECT assay of radiolabeled monoclonal antibodies. Office of Scientific and Technical Information (OSTI), février 1992. http://dx.doi.org/10.2172/7197646.

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Jaszczak, R. J. SPECT assay of radiolabeled monoclonal antibodies. Office of Scientific and Technical Information (OSTI), février 1992. http://dx.doi.org/10.2172/7288347.

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Borgford, Thor. Human-based Polyclonal Antibodies to Ricin. Fort Belvoir, VA : Defense Technical Information Center, mai 2010. http://dx.doi.org/10.21236/ada533217.

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Clynes, Raphael. Cytotoxic Mechanisms of Tumor Specific Antibodies. Fort Belvoir, VA : Defense Technical Information Center, octobre 2002. http://dx.doi.org/10.21236/ada411736.

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Clynes, Raphael. Cytotoxic Mechanisms of Tumor Specific Antibodies. Fort Belvoir, VA : Defense Technical Information Center, octobre 2000. http://dx.doi.org/10.21236/ada392896.

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