Littérature scientifique sur le sujet « Amanitine »
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Articles de revues sur le sujet "Amanitine"
Kubicka, Magdalena, Joanna Wilk, Paweł Dębiec, Krystian Cholewa, Magdalena Makarewicz et Adrianna Szymańska. « Amanitine poisoning - cases, management, therapy results ». Journal of Education, Health and Sport 13, no 4 (1 mars 2023) : 276–80. http://dx.doi.org/10.12775/jehs.2023.13.04.032.
Texte intégralMydlík, M. « Haemoperfusion of Alfa Amanitine -- In Vitro Study ». Toxicology Letters 78 (août 1995) : 59. http://dx.doi.org/10.1016/03784-2749(59)4855b-.
Texte intégralGicquel, T., S. Lepage, O. Tribut, B. Duretz et I. Morel. « O44 : Dosage des amatoxines (α-amanitine, β-amanitine) et de la phalloidine dans les urines par LC-HR-MS ». Toxicologie Analytique et Clinique 26, no 2 (juin 2014) : S25—S26. http://dx.doi.org/10.1016/s2352-0078(14)70052-6.
Texte intégralVlaskin, D. N., E. T. Gainullina, O. V. Klyuster, I. V. Rybal’chenko, S. B. Ryzhikov et V. F. Taranchenko. « Express method for detection of Amanita phalloides amanitine toxins ». Bulletin of Experimental Biology and Medicine 141, no 1 (janvier 2006) : 110–11. http://dx.doi.org/10.1007/s10517-006-0107-2.
Texte intégralSchenk, M., S. Rubitschek, C. Thiel, K. Knubben, M. M. Morgalla, A. Etspüler et A. Königsrainer. « AMANITINE INTOXICATION IN A PORCINE MODEL : WHEN TRANSPLANT, WHEN WAIT FOR REGENERATION ? » Transplantation 86, Supplement (juillet 2008) : 198. http://dx.doi.org/10.1097/01.tp.0000332246.68047.7d.
Texte intégralMuraoka, Shinjiro, Nobuko Fukamachi, Kiyohisa Mizumoto et Takao Shinozawa. « Detection and Identification of Amanitins in the Wood-Rotting Fungi Galerina fasciculata andGalerina helvoliceps ». Applied and Environmental Microbiology 65, no 9 (1 septembre 1999) : 4207–10. http://dx.doi.org/10.1128/aem.65.9.4207-4210.1999.
Texte intégralFeigel, Bartłomiej, ariusz Zuba et Wojciech Lechowicz. « Screening method for the analysis of blood and urine for the presence of naturally occurring toxic compounds from mushrooms (fungi) using the LC-MS method ». Problems of Forensic Sciences, no 126-127 (29 mars 2022) : 137–51. http://dx.doi.org/10.4467/12307483pfs.20.008.15448.
Texte intégralFlammer, René, et Katharina M. Schenk-Jäger. « Pilzvergiftungen – die Schattenseiten des Myzetismus ». Therapeutische Umschau 66, no 5 (1 mai 2009) : 357–64. http://dx.doi.org/10.1024/0040-5930.66.5.357.
Texte intégralRėkutė, Skirmantė, Marius Miglinas et Laurynas Rimševičius. « DAŽNIAUSI APSINUODIJIMO GRYBAIS SINDROMAI IR INKSTŲ PAŽEIDIMAI ». Medicinos teorija ir praktika 22, no 3 (2 janvier 2017) : 213–17. http://dx.doi.org/10.15591/mtp.2016.033.
Texte intégralBever, Candace S., Kenneth D. Swanson, Elizabeth I. Hamelin, Michael Filigenzi, Robert H. Poppenga, Jennifer Kaae, Luisa W. Cheng et Larry H. Stanker. « Rapid, Sensitive, and Accurate Point-of-Care Detection of Lethal Amatoxins in Urine ». Toxins 12, no 2 (15 février 2020) : 123. http://dx.doi.org/10.3390/toxins12020123.
Texte intégralThèses sur le sujet "Amanitine"
Le, Daré Brendan. « Xénobiotiques hépatotoxiques : études de métabolisme et mécanismes d’action ». Thesis, Rennes 1, 2021. http://www.theses.fr/2021REN1B005.
Texte intégralXenobiotic-induced hepatotoxicity is an extremely rich subject, given the multiple mechanisms and actors involved. This translational work aims to improve ethanol and amanitins (powerful fungal toxins) hepatotoxic mechanisms understanding, in order to provide new elements to optimize the therapeutic management of intoxicated patients. In a first step, we provide additional elements of understanding on macrophages response mechanisms to ethanol. These xenobiotic-cell interactions, shown through the P2X7 receptor induction example, seem to contribute in alcoholic liver damage severity, and testify to the macrophages plasticity in pathological situations. These results suggest in particular the interest of P2X7 receptor antagonist’s development in the treatment of alcoholism. In a second step, we are applied molecular networking, which allows the visualization of complex data acquired by LC-MS/MS, to xenobiotic metabolism study. The acebutolol metabolism example, in the context of voluntary drug intoxication on the one hand, and the in vitro quetiapine metabolism study on the other hand, have provided consistent evidence concerning molecular network interest in this context. In a third and final step, the molecular network application allowed us to rule out the hypothesis of an in vivo and in vitro amanitins metabolism. Moreover, our results show that the hepatocyte-like cellular model of differentiated HepaRG is a relevant model in amanitins study, and show the mitochondrial ROS production implication in these substances toxicity
Nakaya, Helder Takashi Imoto. « Identificação e análise de expressão de RNAs intrônicos não codificadores humanos ». Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-08052007-144816/.
Texte intégralIn this work, we show large-scale studies of antisense noncoding RNAs transcribed from intronic regions of human genes. The correlation of expression levels of some intronic transcripts to the degree of tumor differentiation in prostate cancer points to the biological relevance of these messages in complex diseases such as cancer. We also evaluated the existence of a common mechanism of regulation of transcription shared by protein-coding mRNAs and intronic RNAs by measuring the effect of androgen on the transcriptional profile of a prostate cancer cell line. Survey of mRNA and EST public databases revealed more than 55,000 Totally Intronic Noncoding (TIN) RNAs transcribed from the introns of 74% of all unique RefSeq genes. Guided by this information, we designed an oligoarray platform containing sense and antisense probes for each of 7,520 randomly-selected TIN transcripts plus probes for the corresponding protein-coding genes. We identified exonic and intronic tissue-specific expression signatures for human liver, prostate and kidney. The most highly expressed antisense TIN RNAs were transcribed from introns of proteincoding genes enriched in the \"Regulation of transcription\" class. RNA Polymerase II inhibition resulted in increased expression of a fraction of the intronic RNAs in cell cultures, suggesting that other RNA polymerases may be involved in their biosynthesis. A subset of intronic and protein-coding signatures transcribed from the same genomic loci has correlated expression patterns, suggesting that intronic RNAs regulate the abundance or the pattern of exon usage in protein-coding messages. We have identified diverse intronic RNA expression patterns, indicating that they may have regulatory roles. This gene-oriented approach, using a combined intronic/exonic microarray should permit further comparative analysis of intronic transcription under various physiological and pathological conditions, thus advancing current knowledge about the biological functions of these noncoding RNAs.
Amaral, Paulo de Paiva Rosa. « Estudo da biossíntese e regulação de RNAs não-codificadores intrônicos em células humanas ». Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-03012007-000256/.
Texte intégralIt has been recently shown that the bulk of the transcription in human cells is comprised of non-protein-coding RNAs (or noncoding RNAs - ncRNAs) transcribed from introns and intergenic regions of the genome. Previous work from our group has demonstrated that expression of long intronic ncRNAs can be correlated to the degree of prostate tumor differentiation, underscoring the physiological relevance of these transcripts. However, the properties, functions, and regulation of this huge population of ncRNAs remain largely unknown. The present work aimed to investigate the biosynthesis of intronic ncRNAs and aspects of its regulation in human cells, focusing on the contribution of RNA Polymerase II (RNAP II). Initially, the model of regulation of gene expression by androgen hormone was used in order to evaluate the participation of the RNAP II transcription factor Androgen Receptor (AR) in the transcriptional regulation of intronic ncRNAs. Chromatin immunoprecipitation experiments revealed the binding of the AR in an androgen response element (ARE) present in a putative promoter driving the expression of an antisense intronic transcript in Myo5A locus in LNCaP cells. The interaction occurred in an androgen-inducible fashion, along with the up-regulation of the transcript, suggesting that hormone activation occurred in a direct manner mediated by the AR. In a different approach, the effect of RNAP II inhibition with α-amanitin for 24 h in LNCaP cells was analyzed using an oligoarray representing totally and partially intronic transcripts, as well as exons of proteincoding genes. The expression of less than 20 % of the intronic transcripts was affected by the treatment, contrasting to a significantly higher fraction observed for exonic messages (40 %). Moreover, most differentially expressed intronic transcripts were down-regulated, but strikingly 13 to 16 % were up-regulated in cells with blocked RNAP II, while this fraction for exonic transcripts was about 2 %. The results described here demonstrate that RNAP II in fact plays a role in intronic transcription in human cells, but also highlight that another transcriptional system may account for the biogenesis of a fraction of intronic ncRNAs.
Brückner, Florian. « Molecular basis of translocation, alpha-amanitin inhibition, and CPD damage recognition by RNA polymerase II ». Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-86461.
Texte intégralBrückner, Florian. « Molecular basis of translocation, alpha-amanitin inhibition, and CPD damage recognition by RNA polymerase II ». kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/8646/.
Texte intégralCHAUD, JEAN-PAUL. « L'intoxication phalloidienne : a propos de quatre observations recensees dans le departement des alpes-maritimes ». Nice, 1988. http://www.theses.fr/1988NICE6539.
Texte intégralBENVENUTO, VINCENT. « Intoxication phalloidienne : aspect botanique, toxicologique, clinique, therapeutique et preventif ». Saint-Etienne, 1989. http://www.theses.fr/1989STET6215.
Texte intégralDietrich, David John. « Synthesis and evaluation of probes of RNA polymerase II : adaptation of the bicyclic scaffold of the octapeptide amanitin ». Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/27427.
Texte intégralKorsak, Barbara [Verfasser]. « DUPA α-Amanitin Conjugates for Targeted Prostate Cancer Therapy - Optimization and Evaluation of In Vivo Potency / Barbara Korsak ». Bielefeld : Universitätsbibliothek Bielefeld, 2021. http://d-nb.info/1237815606/34.
Texte intégralSEITZ, ISABELLE. « Pharmacologie et toxicologie de l'amanite tue-mouche : ses aspects historiques et modernes ». Strasbourg 1, 1991. http://www.theses.fr/1991STR15023.
Texte intégralLivres sur le sujet "Amanitine"
Mullersman, Jerald Eric. Chemical modification of alpha-amanitin to yield derivatives suitable for conjugation to proteins via reductive alkylation. 1986.
Trouver le texte intégralTamin, Azaibi. Molecular genetic analysis of vaccinia virus genes which confer resistance to alpha-amanitin. 1989.
Trouver le texte intégralChapitres de livres sur le sujet "Amanitine"
Vidal, C., et W. R. Külpmann. « Amanitine ». Dans Lexikon der Medizinischen Laboratoriumsdiagnostik, 1–2. Berlin, Heidelberg : Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_159-1.
Texte intégralVidal, C., et W. R. Külpmann. « Amanitine ». Dans Springer Reference Medizin, 83–84. Berlin, Heidelberg : Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_159.
Texte intégralFaulstich, Heinz, et Theodor Wieland. « New Aspects of Amanitin and Phalloidin Poisoning ». Dans Advances in Experimental Medicine and Biology, 309–14. Boston, MA : Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0361-9_24.
Texte intégralFenoil, R., R. Alfieri et G. Weisz. « A Rapid and Sensitive HPLC Method for Determination of Alpha Amanitin in Urine ». Dans Developments in Analytical Methods in Pharmaceutical, Biomedical, and Forensic Sciences, 143–46. Boston, MA : Springer US, 1987. http://dx.doi.org/10.1007/978-1-4899-3526-7_16.
Texte intégral« Amanitin (C39H54N10O13S) ». Dans Encyclopedia of Genetics, Genomics, Proteomics and Informatics, 74. Dordrecht : Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_599.
Texte intégral« Amanitin Toxicosis ». Dans Clinical Veterinary Advisor, 21–22. Elsevier, 2012. http://dx.doi.org/10.1016/b978-1-4160-9979-6.00014-3.
Texte intégral« A-I (Abscisic acid to Amanitins) ». Dans RÖMPP Encyclopedia Natural Products, sous la direction de Wolfgang Steglich, Burkhard Fugmann et Susanne Lang-Fugmann. Stuttgart : Georg Thieme Verlag, 2000. http://dx.doi.org/10.1055/b-0036-133798.
Texte intégralArici, M. Aylin, et Yesim Tuncok. « Mushroom-related toxins, alpha amanitin, and usage of antioxidants : Directions toward antioxidant capacity ». Dans Toxicology, 447–56. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-12-819092-0.00044-3.
Texte intégral« Raise of a Monoclonal Antibody Against et-Amanitin and Studies on its Molecular Interaction with Amatoxin Peptides ». Dans Proceedings of the Fifth USSR-FRG Symposium on Chemistry of Peptides and Proteins, Odessa, USSR, May 16–20, 1985, 331–38. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858846-031.
Texte intégralActes de conférences sur le sujet "Amanitine"
Kulke, Michael, Anikó Pálfi, Christoph Müller, Werner Simon, Susanne Werner-Simon, Christian Lutz, Torsten Hechler et Andreas Pahl. « Abstract 735 : SAR of amanitin and optimization of linker-amanitin derivatives for solid tumors ». Dans Proceedings : AACR Annual Meeting 2018 ; April 14-18, 2018 ; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-735.
Texte intégralHechler, Torsten, Aniko Palfi, Christoph Müller, Christian Lutz, Andreas Pahl et Michael Kulke. « Abstract 62 : CD19 - a potential target for Amanitin-based ADCs ». Dans Proceedings : AACR Annual Meeting 2017 ; April 1-5, 2017 ; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-62.
Texte intégralPalfi, Aniko, Torsten Hechler, Christoph Mueller, Andreas Pahl et Michael Kulke. « Abstract 2973 : CD269 - A promising target for amanitin based ADCs ». Dans Proceedings : AACR 107th Annual Meeting 2016 ; April 16-20, 2016 ; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2973.
Texte intégralHechler, Torsten, Christoph Müller, Andreas Pahl et Jan Anderl. « Abstract 633 : Amanitin-based ADCs with an improved therapeutic index ». Dans Proceedings : AACR 106th Annual Meeting 2015 ; April 18-22, 2015 ; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-633.
Texte intégralBai, Xueke, Peixi Jiang et Yuyou Wu. « Toxic Mechanisms of α-Amanitin and Its Potential to Fight Cancer ». Dans The International Conference on Biomedical Engineering and Bioinformatics. SCITEPRESS - Science and Technology Publications, 2022. http://dx.doi.org/10.5220/0011378000003443.
Texte intégralAnderl, Jan, Christoph Müller, Brigitte Heckl-Östreicher et Roland Wehr. « Abstract 3616 : Highly potent antibody-amanitin conjugates cause tumor-selective apoptosis ». Dans Proceedings : AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011 ; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3616.
Texte intégralHechler, Torsten, Michael Kulke, Christoph Mueller, Andreas Pahl et Jan Anderl. « Abstract 664 : Amanitin-based antibody-drug conjugates targeting the prostate-specific membrane antigen ». Dans Proceedings : AACR Annual Meeting 2014 ; April 5-9, 2014 ; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-664.
Texte intégralPálfi, Anikó, Christian Breunig, Torsten Hechler, Christoph Müller, Christian Lutz, Andreas Pahl et Michael Kulke. « Abstract 740 : Preclinical evaluation of an anti-PSMA antibody-targeted amanitin conjugate (ATAC) ». Dans Proceedings : AACR Annual Meeting 2018 ; April 14-18, 2018 ; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-740.
Texte intégralBraun, Alexandra, Aniko Palfi, Christoph Mueller, Torsten Hechler, Andreas Pahl et Michael Kulke. « Abstract 910 : Amanitin-based ADCs targeting PSMA as novel therapeutic modality for prostate cancer therapy ». Dans Proceedings : AACR Annual Meeting 2021 ; April 10-15, 2021 and May 17-21, 2021 ; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-910.
Texte intégralVoss, Stephanie, Aniko Palfi, Christoph Mueller, Andreas Pahl, Torsten Hechler et Michael Kulke. « Abstract 915 : Preclinical evaluation of anti-CD37 antibody-targeted amanitin conjugates (ATAC) in B-cell malignancies ». Dans Proceedings : AACR Annual Meeting 2021 ; April 10-15, 2021 and May 17-21, 2021 ; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-915.
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