Bibliographies thématiques / AARS2

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Littérature scientifique sur le sujet « AARS2 »

Auteur : Grafiati
Publié le 9 mars 2023
Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "AARS2"

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Lakshmanan, Rahul, Matthew E. Adams, David S. Lynch, et al. "Redefining the phenotype of ALSP and AARS2 mutation–related leukodystrophy." Neurology Genetics 3, no. 2 (2017): e135. http://dx.doi.org/10.1212/nxg.0000000000000135.

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Objective:To provide an overview of the phenotype of 2 clinically, radiologically, and pathologically similar leukodystrophies, adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) and alanyl-transfer RNA synthetase 2 mutation–related leukodystrophy (AARS2-L), and highlight key differentiating features.Methods:ALSP and AARS2-L cases were identified from the adult-onset leukodystrophy database at our institution. In addition, cases with imaging findings were identified from a literature review. The phenotypic features were determined by combining published cases with
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Axelsen, Tobias Melton, Tzvetelina Lubenova Vammen, Mads Bak, Nelsan Pourhadi, Christian Midtgaard Stenør, and Sabine Grønborg. "Case report: ‘AARS2 leukodystrophy’." Molecular Genetics and Metabolism Reports 28 (September 2021): 100782. http://dx.doi.org/10.1016/j.ymgmr.2021.100782.

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Bhardwaj, Priya, Christoffer Rasmus Vissing, Niels Kjær Stampe, et al. "Reassessment of Gene-Elusive Familial Dilated Cardiomyopathy Leading to the Discovery of a Homozygous AARS2 Variant—The Importance of Regular Reassessment of Genetic Findings." Cardiogenetics 11, no. 3 (2021): 122–28. http://dx.doi.org/10.3390/cardiogenetics11030013.

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Background: AARS2 encodes the mitochondrial protein alanyl-tRNA synthetase 2 (MT-AlaRS), an important enzyme in oxidative phosphorylation. Variants in AARS2 have previously been associated with infantile cardiomyopathy. Case summary: A 4-year-old girl died of infantile-onset dilated cardiomyopathy (DCM) in 1996. Fifteen years later, her 21-year-old brother was diagnosed with DCM and ultimately underwent heart transplantation. Initial sequencing of 15 genes discovered no pathogenic variants in the brother at the time of his diagnosis. However, 9 years later re-screening in an updated screening
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Duzkale, Neslihan, Oguz Lafci, Reyhan Araz, Haktan Bagis Erdem, Mehlika Panpalli Ates, and Halil Onder. "Report of a progressive leukoencephalopathy with ovarian failure (LKENP) case with compound heterozygous genotype and a novel variant: AARS2:c.2358_2364+7dup." Neurology Asia 29, no. 4 (2024): 1181–85. https://doi.org/10.54029/2024zvd.

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Leukoencephalopathies are a heterogeneous group of diseases in which many acquired and hereditary factors play a role in its etiopathogenesis. In recent years, Alanyl-tRNA synthetase 2 (AARS2), encoded by the nuclear genome, has been identified as the causative gene in a small number of patients. The AARS2 gene is responsible for the “progressive leukoencephalopathy with ovarian failure (LKENP)” phenotype, an extremely rare syndrome characterized by progressive leukoencephalopathy and premature ovarian failure. In this case report; we describe the delayed diagnosis of LKENP by genetic analysis
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Dallabona, C., D. Diodato, S. H. Kevelam, et al. "Novel (ovario) leukodystrophy related to AARS2 mutations." Neurology 82, no. 23 (2014): 2063–71. http://dx.doi.org/10.1212/wnl.0000000000000497.

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Parra, Sahyli Perez, Stephan H. Heckers, William R. Wilcox, Colin David Mcknight, and H. A. Jinnah. "The emerging neurological spectrum of AARS2-associated disorders." Parkinsonism & Related Disorders 93 (December 2021): 50–54. http://dx.doi.org/10.1016/j.parkreldis.2021.10.031.

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van der Knaap, Marjo S., and Truus E. M. Abbink. "Ovarioleukodystrophy: Vanishing white matter versus AARS2-related ovarioleukodystrophy." Clinical Neurology and Neurosurgery 171 (August 2018): 195. http://dx.doi.org/10.1016/j.clineuro.2018.06.024.

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Szpisjak, Laszlo, Nora Zsindely, Jozsef I. Engelhardt, Laszlo Vecsei, Gabor G. Kovacs, and Peter Klivenyi. "Novel AARS2 gene mutation producing leukodystrophy: a case report." Journal of Human Genetics 62, no. 2 (2016): 329–33. http://dx.doi.org/10.1038/jhg.2016.126.

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Kuo, Molly E., Anthony Antonellis, and Vikram G. Shakkottai. "Alanyl-tRNA Synthetase 2 (AARS2)-Related Ataxia Without Leukoencephalopathy." Cerebellum 19, no. 1 (2019): 154–60. http://dx.doi.org/10.1007/s12311-019-01080-y.

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Mao, Yunzi, Jiaojiao Zhang, Qian Zhou, et al. "Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation." Cell Research 34, no. 1 (2024): 13–30. http://dx.doi.org/10.1038/s41422-023-00864-6.

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AbstractOxidative phosphorylation (OXPHOS) consumes oxygen to produce ATP. However, the mechanism that balances OXPHOS activity and intracellular oxygen availability remains elusive. Here, we report that mitochondrial protein lactylation is induced by intracellular hypoxia to constrain OXPHOS. We show that mitochondrial alanyl-tRNA synthetase (AARS2) is a protein lysine lactyltransferase, whose proteasomal degradation is enhanced by proline 377 hydroxylation catalyzed by the oxygen-sensing hydroxylase PHD2. Hypoxia induces AARS2 accumulation to lactylate PDHA1 lysine 336 in the pyruvate dehydr
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Thèses sur le sujet "AARS2"

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DIODATO, DARIA. "Identification and functional validation of new mtDNA and nuclear gene variants responsible for mitochondrial disorders." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/50549.

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My project has been focused on the identification and validation of new mitochondrial gene variants and new mitochondria-related genes. The first report is about a woman presenting with a stroke-like episode and an history of severe hearing loss, frequent migraines, exercise intolerance, myalgias and limb-girdle muscle weakness indicating a slowly progressive myopathy and secondary amenorrhea with low gonadotropin levels. A muscle biopsy showed ragged-red, cytochrome c oxidase-negative fibers, and an isolated defect of cytochrome c oxidase activity in muscle mitochondria and sequence analysi
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Hausmann, Corinne D. "Multi-Aminoacyl-Trna Synthetase Complexes In Archaeal Translation." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1213641006.

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Guth, Ethan. "tRNA Identity Mediated Control of the Catalytic mechanism in E. coli Histidyl-tRNA Synthetase." ScholarWorks @ UVM, 2008. http://scholarworks.uvm.edu/graddis/98.

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The aminoacyl-tRNA synthetases (aaRSs) are the universal set of enzymes responsible for attaching amino acids to tRNA to be used as substrates in the process of protein translation. As these enzymes act at the transition between nucleic acids and proteins, their specificity of action is critical for maintaining the fidelity of the genetic code. From a mechanistic standpoint, aaRS specificity is enforced by a complex series of tRNA structural and chemical elements that collectively make up its identity set and serve to distinguish one tRNA from another. Based on sequence, structure, and
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Sanders, Michael. "THE EFFECT OF IMMEDIATE FEEDBACK AND AFTER ACTION REVIEWS (AARS) ON LEARNING, RETENTION AND TRANSFER." Master's thesis, University of Central Florida, 2005. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3657.

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An After Action Review (AAR) is the Army training system's performance feedback mechanism. The purpose of the AAR is to improve team (unit) and individual performance in order to increase organizational readiness. While a large body of knowledge exists that discusses instructional strategies, feedback and training systems, neither the AAR process nor the AAR systems have been examined in terms of learning effectiveness and efficiency for embedded trainers as part of a holistic training system. In this thesis, different feedback methods for embedded training are evaluated based on the timing an
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Schwerdtner, Annegret [Verfasser], and Florian [Akademischer Betreuer] Baumann. "Atlanto-axiale Rotationssubluxation (AARS) im Kindesalter - Diagnostik, Therapie und Langzeitergebnisse aus manualmedizinischer Sicht / Annegret Schwerdtner ; Betreuer: Florian Baumann." Regensburg : Universitätsbibliothek Regensburg, 2020. http://d-nb.info/1204635889/34.

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Aarse, Janna Maria [Verfasser], Denise [Gutachter] Manahan-Vaughan, and Stefan [Gutachter] Herlitze. "Investigations of the functional mechanisms underlying communication between the cerebellum and the hippocampus / Janna Maria Aarse ; Gutachter: Denise Manahan-Vaughan, Stefan Herlitze." Bochum : Ruhr-Universität Bochum, 2017. http://d-nb.info/1125106026/34.

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Kuzmishin, Nagy Alexandra Burden. "Maintaining Fidelity of Translation by Bacterial Trans-Editing Proteins:Caulobacter crescentus ProXp-ala and Rhodopseudomonas palustris ProXp-x." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1563478757446243.

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Holmborn, Towe. "Zooplankton growth and trophic linkages : Implications for fish feeding conditions in the Baltic Sea." Doctoral thesis, Stockholms universitet, Systemekologiska institutionen, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-29485.

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The aim of this Thesis was to improve our understanding and assessment of feeding conditions for zooplanktivorous fish in the Baltic Sea. We investigated (papers I, II) the usefulness of biochemical proxies for assessments of growth and metabolic rates in the dominant Baltic copepod Acartia bifilosa. A predictive model (paper I) for egg production rate (EPR), based on body size, RNA content, and water temperature, was established using females of different geographical origin. This model demonstrates the usefulness of RNA content as a proxy for growth in zooplankton and, together with abundanc
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Gonzalez, Serrano Ligia Elena. "Caractérisation de l'ArgRS mitochondriale humaine et contribution à la compréhension des pathologies liées aux mutations des aminoacyl-ARNt synthétases mitochondriales." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAJ074/document.

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Les aminoacyl-ARNt synthétases mitochondriales humaines (aaRS mt) sont des enzymes clés de la traduction mitochondriale. Elles catalysent l'aminoacylation des ARNt par les acides aminés correspondent. Des mutations dans leurs gènes sont corrélées à des pathologies avec un large spectre de phénotypes cliniques, mais aux mécanismes moléculaires sous-jacents encore incompris. L'objectif de ce travail de thèse s'intègre dans les axes scientifiques du laboratoire, mais élargit l'intérêt et les connaissance à un système encore peu exploré: l'arginyl-ARNt synthétase mitochondriale (ArgRS mt). Des mut
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Galatolo, Daniele. "An integrated, next-generation approach to identify new genes and new pathways in hereditary ataxias." Doctoral thesis, 2020. http://hdl.handle.net/2158/1188709.

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The Hereditary ataxias (HAs) are a group of heterogenous neurological disorders associated with multiple genetic etiologies and encompassing a wide spectrum of phenotypes, where ataxia is the prominent feature. HAs are characterized by degeneration of Purkinje cell and/or spinocerebellar connections, often associated with defects in additional brain structures, and all patterns of inheritance may occur. Similar to other fields of medical genetics, Next Generation Sequencing (NGS) has entered the HA scenario widening our genetic and clinical knowledge of this condition, but routine NGS applicat
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Livres sur le sujet "AARS2"

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Verhelst, Peter. Aars!: Anatomische studie van de Oresteia. Prometheus, 2000.

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Hansteen, Aasta. Tyve aars kamp: Tilbageblik og fremsyn. [Norges allmennvitenskapelige forskningsråd], 1985.

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Kirkeby, Per. At bygge i Aars: Skitser til musikhus. Vesthimmerlands gymnasium, 1996.

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Burney, DeAnna McKinnie. AARS: Adolescent Anger Rating Sale : professional manual. Psychological Assessment Resources, 2001.

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Glerup, Martin. Fra visnen til vækst: Aars Kommune 1970-2007. Martin Glerup Information, 2007.

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United Nations. Economic Commission for Africa and GIS Society of Ethiopia, eds. AARSE 2010: 8th AARSE Conference, Addis Ababa, Ethiopia, October 25-29, 2010 : earth observation for Africa's development agenda : scientific symposium, exhibition, workshops. GISSE, 2010.

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Jensen, Peter Klint. Preliminary simulations of transformation ratios for the Danish Well AARS - 1A. Riso National Laboratory, 1986.

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Angell, H. Skottetoget: Et 400 aars minde : 26. august 1612-26. august 2012. Silver Fox forl., 2006.

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Bråten, Jens. Aars by og sogn: Træk af udviklingen fra 9000 f. kr. - 1985. Jens Bråten, 1985.

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Verhelst, Peter. Aars!: Anatomische studie van de Oresteia. Prometheus, 2000.

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Chapitres de livres sur le sujet "AARS2"

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Mathews, Rick C. "Exercises and AARs in Emergency Management." In Principles of Emergency Management and Emergency Operations Centers (EOC), 2nd ed. CRC Press, 2021. http://dx.doi.org/10.4324/9781315118345-11.

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Townsend, Lisa, Joan Johnston, William A. Ross, Laura Milham, Dawn Riddle, and Henry Phillips. "An Integrated After Action Review (IAAR) Approach: Conducting AARs for Scenario-Based Training Across Multiple and Distinct Skill Areas." In Engineering Psychology and Cognitive Ergonomics. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-91122-9_20.

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"aaRS." In Encyclopedia of Biophysics. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-16712-6_100025.

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Quek, Chai, Zaiyi Guo, and Douglas L. Maskell. "A Novel Fuzzy Associative Memory Architecture for Stock Market Prediction and Trading." In Contemporary Theory and Pragmatic Approaches in Fuzzy Computing Utilization. IGI Global, 2013. http://dx.doi.org/10.4018/978-1-4666-1870-1.ch007.

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In this paper, a novel stock trading framework based on a neuro-fuzzy associative memory (FAM) architecture is proposed. The architecture incorporates the approximate analogical reasoning schema (AARS) to resolve the problem of discontinuous (staircase) response and inefficient memory utilization with uniform quantization in the associative memory structure. The resultant structure is conceptually clearer and more computationally efficient than the Compositional Rule Inference (CRI) and Truth Value Restriction (TVR) fuzzy inference schemes. The local generalization characteristic of the associ
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Arnez, John G., and Dino Moras. "Atninoacyl-tRNA synthetase-tRNA recognition." In RNA-Protein Interactions. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780199635054.003.0003.

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Abstract Aminoacylation is the first and key step in the translation of genetic messages into proteins. The reaction brings together amino acids and their cognate tRNAs and is catalysed by aminoacyl-tRNA synthetases (aaRSs). In the reaction the amino acid is esterified to one of the hydroxyl groups of the 3'-terminal adenosine; the energy in the overall reaction is supplied by the hydrolysis of ATP.
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Aragão, Iapunira Catarina Sant'Anna, Felipe Matheus Sant'Anna Aragão, André Luis Morelli Lustosa, et al. "ANEURISMA DE ARTÉRIA RENAL: uma revisão de literatura." In Ciências e Saúde. IntegralCare Ciências, 2023. http://dx.doi.org/10.29327/5335422.1-7.

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Esse artigo buscou discutir, através de uma revisão bibliográfica, a prevalência de aneurismas de artérias renais (AARs), seus fatores de risco, além dos melhores métodos diagnósticos, implicações clinicas, epidemiologia e tratamento cirúrgico, visando uma atualização de dados, principalmente, para os profissionais que atuam nesta área. 13 artigos foram selecionados e lidos na íntegra para compor os dados desta pesquisa. Os aneurismas de artéria renal são patologias bastante incomuns, e normalmente se manifestam de forma assintomática. Desse modo, o diagnóstico ocorre, principalmente, de manei
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Denham, Magdalena, and Ashish Kumar Khemka. "Reducing Risk Through Academic Community Engagement in Homeland Security and Emergency Management." In Research Anthology on Service Learning and Community Engagement Teaching Practices. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-6684-3877-0.ch080.

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This inquiry engaged graduate students in the Homeland Security and Emergency Management program course designated as Academic Community Engagement (ACE) at an Institution of Higher Education (IHE) in rural Texas. The purpose was to evaluate an American Red Cross (ARC) risk-reduction Home Fire Campaign initiative and to implement new strategies designed by students and grounded in after action reports (AARs) and principles of emergency management (EM). Vygotsky's model of social learning and Cultural Historical Activity Theory (CHAT) framed the study. Students partnered with the ARC, emergency
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Actes de conférences sur le sujet "AARS2"

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Amanat, Man, Julie S. Cohen, Ali Fatemi, and Amena Fine. "AARS2-related Leukodystrophy Without Ovarian Failure Mimicking Multiple Sclerosis in a Female: A Case Report With a Novel Pathogenic Variant (P4-12.010)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000203410.

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Benoit, Michael J. "AARS: The Automated Aircraft Rework System." In Aerofast Conference & Exposition. SAE International, 1995. http://dx.doi.org/10.4271/952180.

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Davidson, David B., Pietro Bolli, Mirko Bercigli, et al. "Electromagnetic modelling of the SKA-LOW AAVS2 prototype." In 2020 XXXIIIrd General Assembly and Scientific Symposium of the International Union of Radio Science (URSI GASS). IEEE, 2020. http://dx.doi.org/10.23919/ursigass49373.2020.9232307.

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Sokolowski, M., J. W. Broderick, R. B. Wayth, et al. "Preliminary sensitivity verification of the SKA-Low AAVS2 prototype." In 2021 15th European Conference on Antennas and Propagation (EuCAP). IEEE, 2021. http://dx.doi.org/10.23919/eucap51087.2021.9410962.

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Gibson, Joseph W. "After Action Review System (AARS) design and functional capabilities." In the 27th conference. ACM Press, 1995. http://dx.doi.org/10.1145/224401.224807.

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Benoit, Michael. "The Automated Aircraft Rework System (AARS) - A system integration approach." In Conference on Intelligent Robots in Factory, Field, Space, and Service. American Institute of Aeronautics and Astronautics, 1994. http://dx.doi.org/10.2514/6.1994-1225.

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Li, Mingrui, and Meng Su. "Phylogenetic Analysis of aaRS Reveals the Kinship of Amino Acids." In ICCBB '21: 2021 5th International Conference on Computational Biology and Bioinformatics. ACM, 2021. http://dx.doi.org/10.1145/3512452.3512459.

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Zhu, Hanrong, Xiaoyan Ma, and Yixin Huo. "Incorporation of 3-hydroxyphenylalanine into proteins using aaRS/tRNA pair." In ICBIT 2024: 2024 International Conference on Biomedicine and Intelligent Technology. ACM, 2024. https://doi.org/10.1145/3700486.3700489.

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"What LEGAD needs to know? Analysis of AARs from Locked Shields (2012-2018)." In The 19th European Conference on Cyber Warfare. ACPI, 2020. http://dx.doi.org/10.34190/ews.20.075.

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Biswas, Saiib K., Pranab K. Muhuri, and Uttam K. Roy. "AARS: A novel adaptive archive-based efficient counting method for machine learning applications." In 2022 IEEE International Conference on Data Mining Workshops (ICDMW). IEEE, 2022. http://dx.doi.org/10.1109/icdmw58026.2022.00085.

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Rapports d'organisations sur le sujet "AARS2"

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Huppmann, Daniel, Margreth Keiler, Keywan Riahi, and Harald Rieder, eds. Second Austrian Assessment Report on Climate Change | AAR2 - Full Report. Verlag der Österreichischen Akademie der Wissenschaften, 2025. https://doi.org/10.1553/aar2.

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Der Zweite Österreichische Sachstandsbericht zum Klimawandel ist die derzeit größte und wichtigste interdisziplinäre Analyse der Klimawandelfolgen und Darstellung von Handlungsoptionen in Österreich. Ziel ist es, fundierte Informationen über beobachtete und erwartete Klimaänderungen, deren Folgen sowie über Optionen zur Emissionsreduktion und Anpassungsstrategien bereitzustellen. Der Bericht zeigt Handlungsspielräume, aber gibt keine Empfehlungen für oder gegen konkrete Einzelmaßnahmen. Stattdessen zeigt der Bericht Risiken, Chancen, Hindernisse, Zielkonflikte und Synergien zwischen Klimaschut
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Huppmann, Daniel, Margreth Keiler, Keywan Riahi, and Harald Rieder. Second Austrian Assessment Report on Climate Change | AAR2 - Summary for Policymakers. Verlag der Österreichischen Akademie der Wissenschaften, 2025. https://doi.org/10.1553/aar2-spm.

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Huppmann, Daniel, Margreth Keiler, Keywan Riahi, and Harald Rieder. Zweiter Österreichischer Sachstandsbericht zum Klimawandel | AAR2 - Zusammenfassung für die politische Entscheidungsfindung. Verlag der Österreichischen Akademie der Wissenschaften, 2025. https://doi.org/10.1553/aar2-spm-de.

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Athey, J. E., and A. L. Nash. Alaska’s story of radon challenges in a big, arctic, far-flung U.S. state (poster): 2022 American Association of Radon Scientists and Technologists (AARST) International Radon and Vapor Intrusion Symposium, Bellevue, Washington, October 24-26, 2022. Alaska Division of Geological & Geophysical Surveys, 2022. http://dx.doi.org/10.14509/30913.

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Guidelines for Conducting After Action Reviews. Inter-American Development Bank, 2009. http://dx.doi.org/10.18235/0008708.

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Various Methodologies exist for facilitating systematic, collective reflexions of teams (workgroups) and for the identification of lessons learned. These methodologies include after action reviews (ARRs), case studies, and observations of experiences. This document presents guidelines for preparing, conducting, and documenting AARs.
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Pautas para la realización de "after action reviews" o reuniones de reflexión después de la acción. Inter-American Development Bank, 2009. http://dx.doi.org/10.18235/0009740.

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Existen diversas metodologías que facilitan la reflexión sistemática y colectiva de los equipos de trabajo y la identificación de Lecciones Aprendidas. Estas metodologías incluyen los After Action Reviews (ARRs), los Estudios de Caso y los Observatorios de experiencias. Este documento presenta pautas para la preparación, realización y documentación de AARs.
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