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Littérature scientifique sur le sujet « 346.066 6 »

Auteur : Grafiati

Publié le 1 février 2025

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Articles de revues sur le sujet "346.066 6"

Stoyanova, S., et V. Giannouli. « Narcissism in Bulgarian Adults ». European Psychiatry 41, S1 (avril 2017) : S257. http://dx.doi.org/10.1016/j.eurpsy.2017.02.056.

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IntroductionNarcissistic personality disorder influences relationships and beliefs in different life spheres.ObjectiveWe aimed to measure narcissism among Bulgarian adults by establishing validity of two scales measuring narcissism, specifying some social and demographic factors and differentiating narcissistic features.MethodOne hundred and thirty-four Bulgarians (17–62 years old, M = 31; SD = 11) were examined with two scales measuring narcissism. Higher score on Narcissistic personality disorder scale from the Personality Diagnostic Questionnaire-4 correlated positively (r = .346; P < .001) with higher score on A. T. Beck and J. S. Beck's scale measuring Narcissistic beliefs from Personality Belief Questionnaire that indicated their validity.ResultsNo significant gender differences in narcissism were found, with female participants prevailing in the sample (n = 118). Family status (FPDQ−4(4,128) = 0.593; pPDQ-4 = 569; FPBQ(4,128) = 0.295; pPBQ = .881), occupational status – student, employed or unemployed (FPDQ−4(4,128) = 0.593; pPDQ−4 = .569; FPBQ(4,128) = 0.295; pPBQ = .881), secondary or university education (tPDQ−4(112) = 1.809; pPDQ−4 = .073; tPBQ(112) = 1.338; pPBQ = .184), and the length of work experience did not differentiate narcissism (RPDQ−4 = .168; tPDQ−4 = −1.853; pPDQ−4 = .066; RPBQ = .063; tPBQ = −0.681; pPBQ = .497). Advance in age was related to diminished levels of narcissism (RPDQ−4 = .21; R2PDQ−4 = .044; BPDQ−4 = −0.034; tPDQ−4 = −2.463; pPDQ−4 = .015). Higher narcissism was related to the belief of being a special person (70.8%) and to the perceptions of other people as being envy of one's personality–own achievements (60.9%).ConclusionsNarcissistic personality disorder is rare in the studied Bulgarian adult population – 4.5% of the subjects (n = 6) had the highest levels of narcissism on both scales that corresponded to the proportion of 6% prevalence of lifetime narcissism in USA, according to Stinson et al.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Zhao, Caitong, Changdong Fei, Renzheng Chen, Yupeng Liu et Hualin Zhang. « Comparison of clinical outcomes between ticagrelor and clopidogrel in patients with acute coronary syndrome and left ventricle dysfunction undergoing percutaneous coronary intervention : An observational study ». Medicine 103, n^o 36 (6 septembre 2024) : e39620. http://dx.doi.org/10.1097/md.0000000000039620.

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Patients with acute coronary syndrome (ACS) and left ventricular (LV) dysfunction undergoing percutaneous coronary intervention (PCI) need adequate antithrombotic protection. We aim to compare the clinical outcomes between ticagrelor and clopidogrel in these patients. In total, 336 patients with ACS and LV dysfunction who undergoing PCI were included in this retrospective observational study. Of these, 137 received clopidogrel and 199 received ticagrelor. There was a 6-month follow-up period during which clinical outcomes were monitored. The incidence of the composite endpoint (23.1% vs 13.9%, P = .041) and bleeding events (6.5% vs 1.5%, P = .027) in the ticagrelor group were significantly higher compared to the clopidogrel group. Multivariate logistic regression analysis revealed that age (P = .006), hypertension (P = .007), liver insufficiency (P = .022), previous MI (P = .014) and ticagrelor (P = .044) were independent risk factors that affect the efficacy outcome. Age (P = .027) and ticagrelor (P = .016) were the independent risk factors for the safety outcome. Furthermore, in Cox survival regression analysis model, the survival rate of the efficacy endpoint in the clopidogrel group was seemingly higher than in the ticagrelor group (HR = 1.68, 95% CI: 0.97–2.90, P = .065). The survival rate of the bleeding endpoint in the clopidogrel group was higher than in the ticagrelor group (HR = 2.00, 95% CI: 1.17–3.40, P = .011). Compared to clopidogrel, ticagrelor showed increased risk of efficacy outcome and major bleeding events during 6-month follow-up in patients with ACS and LV dysfunction undergoing PCI.

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Higashionna, Takuya, Ryoichiro Iwanaga, Akiko Tokunaga, Akio Nakai, Koji Tanaka, Hideyuki Nakane et Goro Tanaka. « Relationship between Motor Coordination, Cognitive Abilities, and Academic Achievement in Japanese Children with Neurodevelopmental Disorders ». Hong Kong Journal of Occupational Therapy 30, n^o 1 (décembre 2017) : 49–55. http://dx.doi.org/10.1016/j.hkjot.2017.10.002.

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Background/Objective Motor coordination impairment is common in children with neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (AD/HD). The purpose of this study was to investigate the relationship between motor coordination, cognitive ability, and academic achievement in Japanese children with neurodevelopmental disorders. Methods Thirty-four school-age (6–12 years old) children with neurodevelopmental disorders and 34 age-matched typically developing (TD) children were recruited in this study. Correlations between the scores of the Movement Assessment Battery for Children-2 (M-ABC2) and the Kaufman Assessment Battery for Children — Second Edition (K-ABCII) that assesses cognitive abilities, and academic achievement were analyzed. Results The children with neurodevelopmental disorders obtained a lower total score and all component scores on M-ABC2 compared to the TD children. In children with neurodevelopmental disorders, M-ABC2 Manual Dexterity score was significantly correlated with K-ABCII Simultaneous Processing (r = .345, p = .046), Knowledge (r = .422, p = .013), Reading (r = .342, p = .048), Writing (r = .414, p = .017), and Arithmetic (r = .443, p = .009) scores. In addition, M-ABC2 Balance score was significantly correlated with K-ABCII Learning (r = .341, p = .048), Writing (r = .493, p = .004), and Arithmetic (r = .386, p = .024) scores. Conclusion These findings stress that it is essential to accurately identify motor coordination impairments and the interventions that would consider motor coordination problems related to cognitive abilities and academic achievement in Japanese children with neurodevelopmental disorders.

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Li, C., J. Liu, H. Chen et W. Zheng. « POS0114 ABERRANT MONOCYTE SUBSETS IN PATIENTS WITH BEHÇET’S DISEASE ». Annals of the Rheumatic Diseases 80, Suppl 1 (19 mai 2021) : 268.1–268. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1157.

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Background:Behçet’s Disease (BD) is a systemic vasculitis of unknown etiology[1]. Monocytes closely related to inflammation potentially contribute to BD’s pathogenesis. They are classified into three subsets: classical monocytes (CM), intermediate monocytes (IM) and non-classical monocytes (NCM). Abnormalities of monocyte subsets have been reported in many infectious, inflammatory and autoimmune diseases[2-6], but their implication in BD remains elusive.Objectives:To investigate the distribution, phenotypes and functions of monocyte subsets in BD and explore their roles in BD pathogenesis.Methods:The frequencies and phenotypes of monocyte subsets in BD and healthy controls (HC) were determined by flow cytometry, and their correlation with clinical parameters was analyzed. Intracellular cytokines and phosphorylated signal proteins [phosphorylated p65(p-p65) and phosphorylated p38(p-p38)] were determined in LPS-activated monocyte subsets by flow cytometry. Monocyte subsets of BD and HC were sorted and co-cultured with naïve CD4 + T cells, and Th1 cell frequencies were measured on day 5.Results:A higher IM (9.0±3.6 % vs. 4.5±2.0%, p<0.01) and lower NCM (2.6±1.2% vs. 4.2±2.0%, p<0.01) population in BD patients were noted. BD IM were positively correlated with CRP (r=0.5456, p<0.05), ESR (r=0.4683, p=0.05), and the serum level of TNF-a (r=0.7372, p<0.001) and IL-6(r=0.5013, p<0.05). BD NCM were negatively correlated with CRP (r=0.4822, p<0.05) and the serum level of IgM (r=-0.7830, p<0.001). Moreover, BD IM decreased (12.3±3.8% vs. 5.7±3.6%, p<0.05), while BD NCM increased (2.6±1.3% vs. 3.5±1.5%, p<0.01) after BD patients achieved remission. CD11b and CD64 expression on CM, IM and NCM in BD were enhanced. BD CM promoted TNF-a (61.0±11.4% vs 48.3±9.9%, p<0.05) and IL-6 (7.2±5.4% vs1.9±1.7%, p<0.05) production and facilitated Th1 differentiation. BD IM promoted IL-6 production (6.2±3.8% vs 2.6±1.6%, p<0.05). Furthermore, we demonstrated a higher level of p-p65 (12.8±2.9% vs 3.3±1.1%, p<0.01) in BD CM and increased p-p65 (3.2±0.6% vs 0.01±0.01%, p<0.01) and p-p38 (1.1±0.6% vs 0.03±0.01%, p<0.01) in BD IM.Conclusion:To our knowledge, our study is the first study on monocyte subsets in BD. Our data highlighted the aberrant populations of IM and CM in BD, potentially implicated in BD pathogenesis.References:[1]Ahmet, Gül, Pathogenesis of Behçet’s disease: autoinflammatory features and beyond, Semin. Immunopathol. 37 (2015) 413-418.[2]G.Fingerle, A.Pforte, B.Passlick, et al.The novel subset of CD14+/CD16+ blood monocytes is expanded in sepsis patients, Blood. 82 (1993) 3170-3176.[3]M.Moniuszko, A. Bodzenta-Lukaszyk, K. Kowal, et al. Enhanced frequencies of CD14++CD16+, but not CD14+CD16+, peripheral blood monocytes in severe asthmatic patients, Clin. Immunol. 130 (2009) 338-346.[4]M.D.Sanchez, Y.Garcia, C.Montes,et al.Functional and phenotypic changes in monocytes from patients with tuberculosis are reversed with treatment, Microbes. Infec. 8 (2006) 2492-2500.[5]S.Koch, T.Kucharzik, J.Heidemann,et al. Investigating the role of proinflammatory CD16+ monocytes in the pathogenesis of inflammatory bowel disease, Clin. Exp. Immunol. 161 (2010) 332-341.[6]H. Zhu, F. Hu, X. Sun,et al.CD16(+) Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus, Front. immunol. 7 (2016) 512.Disclosure of Interests:None declared

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Avisar, Rahamim, Erez Avisar et Dov Weinberger. « Effect of Coffee Consumption on Intraocular Pressure ». Annals of Pharmacotherapy 36, n^o 6 (juin 2002) : 992–95. http://dx.doi.org/10.1345/aph.1a279.

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BACKGROUND: Many ophthalmologists instruct patients with glaucoma to avoid coffee, although data supporting this practice are insufficient. OBJECTIVE: To estimate the effect of drinking coffee on intraocular pressure (IOP). METHODS: In this crossover study, the effect of the consumption of regular (180 mg caffeine in 200 mL beverage) and decaffeinated coffee (3.6 mg caffeine in 200 mL beverage) was compared in patients with normotensive glaucoma (n = 6) or ocular hypertension (n = 22). IOP was monitored in both groups at 30, 60, and 90 minutes after coffee ingestion. RESULTS: In patients with normotensive glaucoma who drank regular coffee, the mean ± SD changes in IOP at 30, 60, and 90 minutes were 0.9 ± 0.5, 3.6 ± 1.1, and 2.3 ± 0.66 mm Hg, respectively; in those who drank decaffeinated coffee, they were 0.75 ± 0.36, 0.70 ± 0.4, and 0.4 ± 0.6 mm Hg, respectively. The corresponding values in patients with ocular hypertension were as follows: after regular coffee, 1.1 ± 0.7, 3.4 ± 1.0, and 3.0 ± 2.7 mm Hg; and after decaffeinated coffee, 0.6 ± 0.4, 0.9 ± 0.2, and 0.5 ± 0.5 mm Hg. The difference in the change in IOP from baseline after ingestion of regular versus decaffeinated coffee was statistically significant in each group at 60 and 90 minutes. Subjects who drank regular coffee demonstrated a greater elevation in IOP; this elevation may be clinically significant. CONCLUSIONS: Intake of caffeinated beverage (≥180 mg caffeine) may not be recommended for patients with normotensive glaucoma or ocular hypertension.

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Шариков, А. Ю., Д. В. Поливановская, М. В. Амелякина, М. В. Туршатов, А. О. Соловьев et И. М. Абрамова. « Development of technology for instant porridges based on extrudates of rice and distillery stillage of Jerusalem artichoke ». Food processing industry, n^o 10 (28 septembre 2024) : 58–63. http://dx.doi.org/10.52653/ppi.2024.10.10.011.

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Целью являлась разработка технологии и рецептуры каш быстрого приготовления на основе процесса экструзии дробленого риса и высушенной барды топинамбура, полученной в рамках комплексной переработки корнеплода на спирт и пищевые ингредиенты и характеризующейся высоким содержанием в ней пищевых волокон – 70,6 % и белка – 15,8 %. С использованием метода обратной экструзии проведена инструментальная оценка текстуры каш, представленных на российском рынке. Показатели консистенции, адгезии и динамической вязкости сред варьируются в широких пределах. Разработаны рецептуры каш, включающие помимо экструдатов овсяные хлопья и вкусоароматические ингредиенты: сахар, соль, кардамон. Повышение доли высушенной барды топинамбура при экструдировании от 0 до 6 % позволяет увеличить содержание пищевых волокон в кашах до 6 г на 100 г смеси. Это позволяет характеризовать смеси как продукт с высоким содержанием пищевых волокон. В аспекте реологических характеристик отмечен рост динамической вязкости с 2,7 до 3,6 Па•с и силы адгезии с 0,7 до 0,9 Н. Более значимо влияющим на реологию готовых к употреблению каш фактором является содержание в их рецептуре овсяных хлопьев. Повышение их дозировки от 0 до 37,5 % увеличило показатель твердости с 0,9 до 4,3 Н, консистенции – с 12,1 до 44,0 мДж, силы адгезии – с 0,6 до 3,6 Н, работы на преодоление адгезии – с 8,2 до 30,6 мДж. При этом отмечены рост вязкости с 2,4 до 3,7 Па•с и снижение набухаемости с 6 до 5 мл/г смеси. Добавление в рецептуру овсяных хлопьев оказывает положительное влияние на органолептическую оценку продукта за счет увеличения значения дескриптора текстуры. Варьирование количеством высушенной барды топинамбура в экструдатах и овсяных хлопьев в рецептурах каш не оказывает значимого влияния на вкус и запах разработанных, готовых к употреблению продуктов. The goal of the work was to develop a technology and recipes for instant porridge based on the process of extrusion of broken rice and dried stillage obtained as part of the complex processing of Jerusalem artichoke into alcohol and food ingredients and characterized by a high content of dietary fiber – 70.6 % and protein – 15.8 %. Using the back extrusion methodology, an instrumental assessment of the texture of instant porridges presented on the Russian market was carried out. It has been shown that the firmness, consistency, adhesion and dynamic viscosity of media vary widely. Porridge recipes have been developed that include, in addition to extrudates, oat flakes and flavoring ingredients: sugar, salt, cardamom. Increasing the proportion of dried Jerusalem artichoke stillage during extrusion from 0 to 6 % makes it possible to increase the content of dietary fiber in porridges to 6 g per 100 g of mixture. This allows the mixture to be characterized as a product with a high dietary fiber content. In terms of rheological characteristics, an increase in dynamic viscosity from 2.7 to 3.6 Pa s and adhesion force from 0.7 to 0.9 N was noted. A more significant factor influencing the rheology of ready-to-eat porridges is the content of oatmeal in their recipe. Increasing their dosage from 0 to 37.5 % increased firmness from 0.9 to 4.3 N, consistency from 12.1 to 44.0 mJ, adhesion force from 0.6 to 3.6 N, work to overcome adhesion from 8.2 to 30.6 mJ. At the same time, an increase in viscosity from 2.4 to 3.7 Pa s and a decrease in swelling power from 6 to 5 ml/g of the mixture were noted. The addition of oat flakes to the recipe has a positive effect on the sensory evaluation of the product by increasing the value of the texture descriptor. Varying the amount of dried Jerusalem artichoke stillage in extrudates and oat flakes in porridge recipes does not have a significant effect on the taste and smell of the developed ready-to-eat products.

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Chhetri, Sandip, Rachel A. Chicchi et Andrew E. N. Osborn. « Experimental investigation of 0.6 in. diameter strand lifting loops ». PCI Journal 66, n^o 2 (2021) : 71–87. http://dx.doi.org/10.15554/pcij66.2-03.

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Very little experimental data have been published relating to the pullout capacity of prestressing strand lifting loops. To address this gap in knowledge, 13 pullout tests were conducted on strand lifting loops with 0.6 in. (15.24 mm) diameter, 270 ksi (1860 MPa) strand. Straight and bent orientations were tested for single loops at different embedment depths. Loops were embedded in 12 in. (304.8 mm) wide and 44 in. (1117.6 mm) deep concrete blocks and subjected to monotonic, static loading until failure. Marginal bond quality of the strand (18.2 kip [81 kN]), Mohs hardness (3.6), and concrete strength (3000 psi [20.7 MPa]) resulted in an average bond stress value of 400 psi (2758 kPa) at failure. Most tests exhibited pullout failure modes and adequate ductility. Three loops tested at 32 in. (812.8 mm) embedment with 6 in. (152.4 mm), 90-degree bends experienced brittle side-face blowout failures. These failures were due to inclination of the lifting, which led to a reduced edge distance. A safe uniform bond stress of 199 psi (1372 kPa) is recommended for 0.6 in. diameter strand.

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Volodin, P. L., E. V. Ivanova, E. Iu Polyakova et A. V. Fomin. « Spectral OCT Angiography in the Assessment of Biomarkers of Diabetic Macular Edema in Navigation Laser Treatment ». Ophthalmology in Russia 19, n^o 2 (5 juillet 2022) : 334–42. http://dx.doi.org/10.18008/1816-5095-2022-2-334-342.

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Purpose — to study visualized biomarkers before and after navigation laser treatment in patients with diabetic macular edema (DMO) using optical coherence tomography-angiography (OCT-A).Methods. 85 patients (85 eyes) with focal DMO were under observation. The patients were divided into two groups, depending on the method of laser treatment used: group 1 consisted of 50 patients (50 eyes) who underwent navigation sub-threshold laser exposure in micro-pulse and continuous modes with individual selection of energy parameters according to the developed technology (patent RF for invention No. 2752544 of 27.01.2021), in group 2 (35 patients, 35 eyes) laser coagulation was performed according to the type of “modified grid”. The treatment was carried out on the NAVILAS 577S navigation laser system (“OD-OS”, Germany). All patients in both groups underwent high-resolution OCT-A according to the Angio Retina 3×3 mm and HD Angio Retina 6×6 mm protocol. The following biomarkers were evaluated by the OCT-A method: vascular density of the superficial vascular plexus (SCP), deep vascular complex (DCP); the number of microaneurysms and hyperreflective points; the area of the foveal avascular zone, as well as cysts and zones of disorganization of the inner layers of the retina (DRIL), at various times before and after (1, 3 and 6 months) treatment.Results. According to OCT-A, as a result of treatment in group 1, there was an increase in total vascular density from 38.45 ± 0.4 % to 44.85 ± 0.66 % in SCP and from 43.55 ± 0.38 % to 44.85 ± 0.66 % in DCP by 6 months of follow–up. In group 2, the total vascular density in SCP increased from 37.4 ± 0.36 % to 37.85 ± 0.34 %, in DCP from 43.35 ± 0.38 % to 44.05 ± 0.41 %. The number of microaneurysms decreased on average from 12 ± 0.42 to 9 ± 0.3 by 3 months and 7.5 ± 0.26 by 6 months in group 1 and, from 19 ± 0.7 to 15.5 ± 0.6 (3 months) and 13 ± 0.5 (6 months) — in group 2. The number of hyperreflective points decreased in terms of 3 and 6 months in both groups. The area of cysts progressively decreased, and the area of FAZ and DRILS was stable throughout all the follow-up period.Conclusion. OCT-A is a highly informative diagnostic method that allows noninvasively to identify visualized OCT-A biomarkers, as well as to evaluate the effectiveness of navigation laser exposure in patients with diabetic maculopathy with focal diabetic macular edema.

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Herbst, Roy S., Edward B. Garon, Dong-Wan Kim, Byoung Chul Cho, Jose L. Perez-Gracia, Ji-Youn Han, Catherine Dubos Arvis et al. « Long-Term Outcomes and Retreatment Among Patients With Previously Treated, Programmed Death-Ligand 1‒Positive, Advanced Non‒Small-Cell Lung Cancer in the KEYNOTE-010 Study ». Journal of Clinical Oncology 38, n^o 14 (10 mai 2020) : 1580–90. http://dx.doi.org/10.1200/jco.19.02446.

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PURPOSE In the KEYNOTE-010 study, pembrolizumab improved overall survival (OS) versus docetaxel in previously treated, programmed death-ligand 1 (PD-L1)‒expressing advanced non‒small-cell lung cancer (NSCLC) in patients with a tumor proportion score (TPS) ≥ 50% and ≥ 1%. We report KEYNOTE-010 long-term outcomes, including after 35 cycles/2 years or second-course pembrolizumab. METHODS Of 1,033 patients randomly assigned (intention to treat), 690 received up to 35 cycles/2 years of pembrolizumab 2 mg/kg (n = 344) or 10 mg/kg (n = 346) every 3 weeks, and 343 received docetaxel 75 mg/m2 every 3 weeks. Eligible patients with disease progression after 35 cycles/2 years of pembrolizumab could receive second-course treatment (up to 17 cycles). Pembrolizumab doses were pooled because no between-dose difference was observed at primary analysis. RESULTS Pembrolizumab continued to improve OS over docetaxel in the PD-L1 TPS ≥ 50% and ≥ 1% groups (hazard ratio [HR], 0.53; 95% CI, 0.42 to 0.66; P < .00001; and HR, 0.69; 95% CI, 0.60 to 0.80; P < .00001, respectively) after a 42.6-month (range, 35.2-53.2 months) median follow-up. Estimated 36-month OS rates were 34.5% versus 12.7% and 22.9% versus 11.0%, respectively. Grade 3-5 treatment-related adverse events occurred in 16% versus 37% of patients, respectively. Seventy-nine of 690 patients completed 35 cycles/2 years of pembrolizumab; 12-month OS and progression-free survival rates after completing treatment were 98.7% (95% CI, 91.1% to 99.8%) and 72.5% (95% CI, 59.9% to 81.8%), respectively. Seventy-five patients (95%) had objective response (RECIST v1.1, blinded independent central review) and 48 (64%) had ongoing response. Grade 3-5 treatment-related adverse events occurred in 17.7% of patients. Fourteen patients received second-course pembrolizumab: 5 completed 17 cycles, 6 (43%) had partial response, and 5 (36%) had stable disease. CONCLUSION Pembrolizumab provided long-term OS benefit over docetaxel, with manageable safety, durable responses among patients receiving 2 years of treatment, and disease control with second-course treatment, further supporting pembrolizumab for previously treated, PD-L1‒expressing advanced NSCLC.

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Anisimov, M. A., A. V. Bogach, V. V. Glushkov, S. V. Demishev, N. A. Samarin, N. Y. Shitsevalova et N. E. Sluchanko. « Hall Effect in LaB₆ and NdB₆ ». Solid State Phenomena 152-153 (avril 2009) : 525–28. http://dx.doi.org/10.4028/www.scientific.net/ssp.152-153.525.

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To shed more light on the peculiarities of ground state formation in RB6 Hall effect in NdB6 and LaB6 has been investigated on the single crystals at temperatures 2K<T<300K in magnetic fields H < 80kOe. The Hall coefficient RH and resistivity ρ have been measured by the sample rotation technique in fixed magnetic field to be perpendicular to the axis of rotation (<110> for LaB6 and <100> for NdB6). A very similar temperature behavior of RH(T) with the step–like anomaly near T ~ 25K has been established for both magnetic NdB6 and diamagnetic LaB6 at intermediate temperatures T>10K. The temperature independent behaviour of Hall coefficient (RH(LaB6) ~ –3.6•10-4 cm3/C, RH(NdB6) ~ –3.7•10-4 cm3/C) observed in the interval 10K<T<20K allowed to estimate the reduced charge carriers’ concentration n/nR ≈ 1.21±0.03 (nR– the concentration of La (Nd) ions). The Hall mobility μH = RH(T)/ρ(T) estimated for LaB6 and NdB6 was shown to be well fitted by the power law μH ~ T-α where α(LaB6) ≈ 1.5, α(NdB6) ≈ 0.6 at the intermediate temperatures 50K<T<300K and α(LaB6) ≈ 3 in the range 20K<T<50K. The drastic decrease of both the Hall mobility μH and the exponent α is discussed in terms of the magnetic scattering enhancement of conduction electrons on the localized 4ƒ–states of Nd3+ ions.

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Зарецький, О. В. Офіційний та альтернативний дискурси. 1950 - 80-ті роки в УРСР. Київ : Фітосоціоцентр, 2003.

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Яременко, Н. Клуб інтелектуальних ігор. Київ : Шкільний світ ; Видавець Л. Галіцина, 2005.

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Професійне самовизначення старшокласників. Київ : Шкільний світ, 2006.

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« 60.45.10. rinderproduktion ». Dans Agroselekt. Reihe 3 : Tierproduktion Band 34, Heft 6, 937–61. De Gruyter, 1989. http://dx.doi.org/10.1515/9783112648124-006.

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« 60.50.10. Physiologie und pathologie der fortpflanzung ». Dans Agroselekt. Reihe 3 : Tierproduktion Band 34, Heft 6, 1054–58. De Gruyter, 1989. http://dx.doi.org/10.1515/9783112648124-016.

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« 60.50.45. Lebensmittelhygiene ». Dans Agroselekt. Reihe 4 : Veterinärmedizin Band 34, Heft 6, 1135–44. De Gruyter, 1989. http://dx.doi.org/10.1515/9783112642382-016.

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« 60.50.10. Physiologie und Pathologie der Fortpflanzung ». Dans Agroselekt. Reihe 4 : Veterinärmedizin Band 34, Heft 6, 1008–28. De Gruyter, 1989. http://dx.doi.org/10.1515/9783112642382-006.

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« 6. Zu Programm, Anlage und Anfang der doppelseitigen Deduktion (Kap. 3.6–4.5, 123–154) ». Dans Helmuth Plessner : Die Stufen des Organischen und der Mensch, 87–102. De Gruyter, 2017. http://dx.doi.org/10.1515/9783110552966-006.

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Tacchi, Francesco. « 4 Educare per restaurare Cristo nelle anime ». Dans Studi di storia. Venice : Edizioni Ca' Foscari, 2019. http://dx.doi.org/10.30687/978-88-6969-336-6/016.

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« TABLE 9 Mineral Composition of Rye, Wheat, Barley, Corn, Oats, and Rice (mg/100 g, dry wt.) Barley Oats Rice Whole Kernel Whole Kernel Whole Kernel Rye Wheat grain only Corn grain only grain only Phosphorus 380 410 470 400 310 340 400 285 290 Potassium 520 580 630 600 330 460 380 340 120 Calcium 70 60 90 80 30 95 66 68 67 Magnesium 130 180 140 130 140 140 120 90 47 Iron 966 - 274 - 6 Copper 0.90.80.90.2450.30.4 Mangenese 7.55.51.80.65462 Zinc 3.44.44.0 - 3.91.5-2.21.2-2.1 Sodium 3.14.6 11.8 8.63.1-6.92.2-5.1 TABLE 10 Mineral Composition of Sorghum, Triticale, barley contains the highest average levels of phosphorus and Wild Ricea and whole grain rice the lowest (285 mg/100 g). From a di-Sorghum Triticale Wild rice etary standpoint, barley, corn, and rice are considered moderate sources of phosphorus (100-200 mg/100 g) ; Phosphorus 405 0.19% 0.4-0.5% buckwheat, millet, oats, brown rice, rice bran, rye, wheat, Potassium 400 1.21% 0.4-0.6% wheat germ, wheat bran and wild rice are classified as high Calcium 20 0.21% 0.01-0.03% sources (200-1200 mg/100 g) (Tables 13-16). Magnesium 150 0.16% 0.1-0.2% The data in Tables 13-16 indicate that quantities of Iron 6 12-51 ppm Copper 0.53.9 ppm 1.8-14.5 ppm phosphorus vary significantly from one wheat variety to Manganese 1.5 37 ppm another. This variation can also be seen in barley. In con-Zinc 0.0008% 36 ppm 40-121 ppm trast, phosphorus content from one variety of rye or oats to Sodium 0.00008% another does not vary significantly. In the Syvalahti and Korkman [42] study, phosphorus content of the grain was 'mg/100 g (dry wt.) unless otherwise noted. not affected by the fertilizer treatments of spring wheat, Refs. 15, 17, 35, 36. barley, and rye. Significant differences in phosphorus con-tent were seen in winter wheat and oats when different fer-[40], calcium levels in various rye and oat varieties tend to tilizer treatments were used (Tables 17-21). be reasonably consistent (Tables 13-16). The effects of various fertilizer treatments on mineral C. Magnesium content of spring and winter wheat, barley, oats and rye Eighty-seven percent of the magnesium in cereal grains is grown in 10 localities in Finland are shown in Tables located in the aleurone layer [34]. Because magnesium 17-21. These data [42] show that fertilizer treatment did binds with phytic acid, much of the magnesium is probably not result in a variation in calcium content in the grains present as Ca5 Mg phytate or as potassium-magnesium studied (Tables 17-21). phytate [34]. The remainder is likely to be present in phos-B. Phosphorus phates and sulfates [34]. From a dietary standpoint, brown rice is considered to Compared to other minerals, phosphorus is found in large be a poor source of magnesium (50-100 mg/100 g). Mod-quantities in cereal grains. It is mostly associated with erately good sources (100-200 mg/100 g) include barley, phytic acid (myoinositol hexaphosphoric acid) and its millet, oats, rye, wheat, and wild rice. Buckwheat, wheat salts. In wheat, rice, and maize, 80% or more of the total bran, and wheat germ are considered to be high sources of phosphorus is accounted for by the phytate [34]. Over 80% this mineral (200-400 mg/100 g) [1-3,6,8,37,43] (Tables of the phytate is located in the aleurone portion of wheat 13-16). In the mid-1970s the Food and Nutrition Board and the pericarp of rice ; in corn, over 80% is found in the proposed that wheat flour be enriched with magnesium at germ [34]. In wheat, phosphorus becomes incorporated the rate of 200 mg/lb flour [9,14]. However, this proposal into phytic acid during maturation [34]. As seen in Table 9, was never implemented. » Dans Handbook of Cereal Science and Technology, Revised and Expanded, 501–9. CRC Press, 2000. http://dx.doi.org/10.1201/9781420027228-49.

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Actes de conférences sur le sujet "346.066 6"

Silva, Ana Clara Bacelar, et Fernanda de Souza Silva. « Physiotherapy intervention through early stimulation in premature babies ». Dans V Seven International Multidisciplinary Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/sevenvmulti2024-076.

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According to the Ministry of Health (2021), in Brazil, approximately 340 thousand premature births occur annually, which represents an average of 931 babies per day or approximately 6 premature births every 10 minutes. Premature babies are defined as those born before 37 weeks of gestation, considering that a complete pregnancy varies from 37 to 42 weeks.

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Cazacu, Mihail, Constantanicoleta Bodea, Cristian Cucu et Maria iuliana Dascalu. « USING THE ACTIVITY THEORY TO IDENTIFY THE CHALLENGES OF DESIGNING ELEARNING TOOLS BASED ON MACHINE LEARNING FOR SECURITY OPERATIONS CENTERS ». Dans eLSE 2019. Carol I National Defence University Publishing House, 2019. http://dx.doi.org/10.12753/2066-026x-19-060.

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Using the Activity Theory to Identify the Challenges of Designing eLearning Tools based on Machine Learning for Security Operations Centers Mihail CAZACU Economic Informatics Doctoral School, University of Economic Studies, Romania, Romana Square 6, Bucharest, Romania mihail.cazacu@gmail.com Maria-Iuliana DASC?LU Department of Engineering in Foreign Languages, Faculty of Engineering in Foreign Languages, University Politehnica of Bucharest, Splaiul Independentei, No 313, Bucharest, Romania maria.dascalu@upb.ro Constanta-Nicoleta BODEA Department of Economic Informatics and Cybernetics, Faculty of Economic Cybernetics, Statistics and Informatics, University of Economic Studies, Romana Square 6, Bucharest, Romania bodea@ase.ro Abstract There is a fast-growing requirement for setting up Security Operation Centers (SOCs), with qualified personnel, mainly due to the increase of demands to protect ITC systems from security breaches, data disruption or unauthorized usage. The 2018 Report of Privacy Rights Clearinghouse mentions that over 8,000 data breaches were reported since 2005, with more than 10 billion records affected. And according to the 2017 study of IBM Security and Ponemon Institute, the average cost of a data breach exceed 3.6 million US dollars. SOCs have the mission to run in this "arms race" against cyber attackers (criminals, spies, terrorists, activists) and to be economically viable, as a profit or a cost center. Development of e-learning tools for continuous enhancing of the professional competences of the SOC's personnel is critical for the successful operation of SOCs. Recent studies have applied the framework of the Activity Theory in order to identify the conflicting priorities which need to be handled by different members of SOCs and have suggested ways to mitigate the risks. While automating mundane tasks is one solution, the issue of automating the automation process itself through Machine Learning, especially in the e-learning activities performed inside SOCs was not often addressed. The paper aims to present the challenges of applying the framework of the Activity Theory in designing e-learning tools based on machine learning methods for SOCs. Some well-established Open Source security tools and machine learning packages will be evaluated for their suitability for developing e-learning tools.

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Borri, D., MFM Santos, RK Kishimoto, RMSO Safranauskas, EDRP Velloso, AAC Coimbra, MS Sielski, RMA Paiva et G. Sousa. « ANÁLISE DE CARIÓTIPO DE AMOSTRAS DE TERAPIA AVANÇADA EM UM LABORATÓRIO DE CITOGENÉTICA DE ROTINA ». Dans Resumos do 55º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial, 34. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s2.9259.

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Objetivo: Avaliar a frequência de alterações citogenéticas (por KT e banda G) em amostras de terapia avançada recebidas entre março de 2015 e janeiro de 2023, bem como a origem celular e a finalidade do estudo. Método: Avaliadas 167 amostras: 101 (60,5%) da instituição e 66 (39,5%) de serviços externos. Tipo celular avaliado [e origem do tecido]: 95 (56,9%) mesenquimais [30 (18%) medula óssea, 17 (10,2%) músculo, 14 (8,4%) periósteo do palato, 14 (8,4%) adipócitos, 13 (7,8%) cordão umbilical, sete (4,2%) polpa dental], 17 (10,2%) células NK [sangue de cordão umbilical], 12 (7,2%) condrócitos [cartilagem], 11 (6,6%) linhagem celular [sete (4,2%) HEK293-3F6, três (1,8%) K562 e uma (0,6%) OCI-AML2], 10 (6%) iPSC [células epiteliais de urina], oito (4,8%) linfócitos [sangue periférico], sete (4,2%) células renais [rim], seis (3,6%) CAR-T [sangue periférico] e uma (0,6%) fibroblasto. Finalidade dos estudos: tratamento [120 (71,9%)]: 39 (23,4%) lesão condral/osteoartrite, 37 (22,2%) incontinência urinária, 21 (12,6%) neoplasias hematológicas, 14 (8,4%) lesão pulmonar Covid e nove (5,4%) citomegalovírus pós-TCTH; pesquisa [47 (28,1%)]: (11,4%) validação de cultivo e expansão celular, 11 (6,6%) autenticidade celular, 10 (6%) processos neurológicos em síndrome de Down e sete (4,2%) doença renal crônica. Amostras para tratamento: 87 (72,5%) KT normal, cinco (4,2%) KT normal com alterações não clonais, nove (7,5%) ausência de metáfases e 19 (15,8%) KT com alterações clonais. Entre estas: 10 (52,6%) trissomias, sete (36,8%) alterações estruturais, uma (5,3%) tetraploidia e uma (5,3%) perda do Y. Amostras para pesquisa: 10 (66,7%) KT complexo (linhagem celular para avaliar autenticidade), três (20%) trissomias e duas (13,3%) alterações estruturais. Conclusão: A manipulação extensa de células e produtos de terapias avançadas pode contribuir para a instabilidade; isso pode aumentar o risco de alterações citogenéticas clonais, sugerindo que tais produtos devam ser descartados. Referência: 1. Borgonovo T, et al. Genetic evaluation of mesenchymal stem cells byG-banded karyotyping in a cell technology center. 2014; 36(3): 202-7.

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Глибка, А. А., М. В. Мазурина, Е. А. Трошина, К. А. Саранцева, Г. Ю. Харкевич, М. В. Волконский, Г. А. Мельниченко et К. К. Лактионов. « ИММУНООПОСРЕДОВАННЫЕ ЭНДОКРИННЫЕ ЗАБОЛЕВАНИЯ У ОНКОЛОГИЧЕСКИХ ; ПАЦИЕНТОВ НА ФОНЕ ТЕРАПИИ ИНГИБИТОРАМИ КОНТРОЛЬНЫХ ТОЧЕК ». Dans X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-260.

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Активное применение ингибиторов контрольных точек иммунного ответа (ИКТИО) в качестве стандарта лечения различных злокачественных новообразований приводит к увеличению числа наблюдаемых различных иммуноопосредованных нежелательных явлений (ИОНЯ), обусловленных активацией иммунной системы. Эндокринные ИОНЯ по частоте выявления занимают 3-е место, уступая лишь поражениям кожи и желудочно-кишечного тракта. ЦЕЛЬ: оценить частоту развития эндокринных ИОНЯ на фоне терапии ИКТИО. МАТЕРИАЛЫ И МЕТОДЫ: в многоцентровое исследование были включены 172 пациента, проходящих противоопухолевое лечение в ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России или ГБУЗ «МГОБ № 62 ДЗМ». Медиана возраста пациентов на момент обследования составила 60 лет [24; 87], соотношение мужчин/женщин (%) – 52,7/47,3. Используемые препараты из группы ИКТИО в исследуемой выборке пациентов: ниволумаб – 60,9% (n = 103); атезолизумаб – 16,6% (n = 28); пембролизумаб – 14,8% (n = 25); пролголимаб – 5,9% (n = 10); комбинированная терапия ипилимумаб + ниволумаб – 1,8% (n = 3). По данным нозологической классификации основного онкологического заболевания (Международная статистическая классификация болезней 10-го пересмотра, МКБ-10) среди исследуемой выборки встречались следующие патологии: злокачественная меланома кожи (С43) – 50,9% (n = 86); злокачественное новообразование бронхов и легкого (С34) – 35,5% (n = 60); злокачественное новообразование самостоятельных (первичных) множественных локализаций (С97) – 8,3% (n = 14); злокачественное новообразование печени и внутрипеченочных желчных протоков (С22) – 3,6% (n = 6); злокачественное новообразование ободочной кишки (С18) – 0,6% (n = 1); злокачественное новообразование шейки матки (С53) – 0,6% (n = 1); злокачественное новообразование тела матки (С54) – 0,6% (n = 1). В исследуемой выборке пациентов осуществлялась оценка: ТТГ, своб. Т4, своб. Т3, АКТГ, кортизола, глюкозы, натрия и калия сыворотки (или плазмы) крови. РЕЗУЛЬТАТЫ: развитие эндокринных иммуноопосредованных нежелательных явлений на фоне терапии ИКТИО выявлено у 15,2% испытуемых. Среди них наиболее часто диагностирована дисфункция щитовидной железы (n = 20). ВЫВОДЫ: развитие поражений органов эндокринной системы на фоне ИКТИО остается неясным и не зависит от выбранного лекарственного препарата, типа опухоли и возраста пациента. При этом эндокринные ИОНЯ не рассматривались как показание для прекращения противоопухолевого лечения. Лишь при выраженных клинических проявлениях на время подбора гормональной терапии осуществление инфузий препаратом ИКТИО было приостановлено.

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Herrlander, Bo. « Novel Gas Cleaning With Integrated Energy Recovery ». Dans 19th Annual North American Waste-to-Energy Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/nawtec19-5415.

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High-energy recovery combined with low emissions to air and water was targeted when Jo¨nko¨ping Energi planned their new Waste to Energy plant at Torsvik in Sweden. The plant is compliant with the new EU Industry Directive and the Waste Frame Directive R-formula, which defines energy recovery levels for recycle of energy. In total about 160 000 tons of municipal (40%) and commercial waste (60%) is annually converted into usable energy. The average heat value is 11,7 MJ/kg. The energy produced is a combination of electricity (14 MWe) and heat (42–56 MWth, depending on electricity production). The heat is recovered both in a boiler and in a condenser. The flue gas condensing system is combined with a heat pump (10 MWth) to optimize the heat recovery rate. The plant is designed to fulfill the requirements set by the Swedish authorities, which are more stringent than the EU emission requirements. Some examples of the plant emissions to air guarantees: dust 5, HCl 5, SO2 20, HF1, Hg 0,03, Cd+Tl 0,05, other HM 0,5 all in mg/Nm3 and dioxin 0,05 ng/Nm3. The flue gas cleaning upstream of the condenser consists of a combination of a semi-dry system and a wet scrubber. The gas cleaning system operating range goes from 60 000 up to 127 000 Nm3/h depending on load and fuel heat value. The semi-dry system is carrying out the major part of the gas cleaning and is sufficient to comply with the air regulations. However, in order to minimize the treatment of the condensate from the condenser the wet scrubber is installed after the semi-dry system and upstream the condenser. The blow down from the scrubber is reused within the plant. Thus the polishing scrubber secures minimal treatment of the condensate to comply with the local stringent limits, particular chlorides, before release to the recipient lake Munksjo¨n. Emissions to water were 2010 nitrogen 1,7 mg/l, Cl <3,6 mg/l, As 0,66 μg/l, Cd <0,07 μg/l, Cr <6 μg/l, Cu 0,8 μg/l, Hg <0,4 μg/l, Ni <0,66 μg/l, Pb<1,2 μg/l, Tl<1,3 μg/l, Zn<7,2 μg/l and PCDD/PCDF 0,0088 ng/l. In the wet scrubber acid stage residual HCl and excess ammonia from the SNCR system are removed. The latter compound is important to capture in order to prevent eutrophication. The combination of a semidry and a wet system enables an optimization of the flue gas cleaning with regard to the different operating situations, taking into account seasonal demand variations as well as fuel alterations. The concept has demonstrated very low emissions combined with low consumption of lime. The possibility to optimize the flue gas cleaning performance is a prerequisite for minimal condensate treatment and optimal energy recovery. The paper will describe the system and the operating experiences.

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Rapports d'organisations sur le sujet "346.066 6"

Dorman, Eleanor, Zara Markovic-Obiago, Julie Phillips, Richard Szydlo et Darren K. Patten. Wellbeing in UK Frontline Healthcare Workers During Peaks One and Three of the COVID-19 Pandemic : A Retrospective Cross-Sectional Analysis. Science Repository, décembre 2022. http://dx.doi.org/10.31487/j.ejgm.2022.01.01.

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Background: COVID-19 had a huge impact on the wellbeing of healthcare workers (HCWs). This is well documented during the first peak of the pandemic. With cases in the UK rising for a third peak, hospitalisations and deaths surpassing the first, there is very little known about the mental health of HCWs during this time. Methods: Using a questionnaire, data was collected from patient-facing staff at Barking, Havering, and Redbridge University Trust to quantify and compare the period prevalence of symptoms of depression, anxiety, and PTSD during the first peak (P1: March-May 2020) and third peak (P3: December 2020-Feburary 2021) of the COVID-19 pandemic as well as wellbeing service use, demographics of responders and what they found most difficult during the peaks. Results: Of 158 responders, only 22·4% felt they had enough access to wellbeing services during P1 and 21·5% in P3. Of those who used wellbeing services 34·4% found them useful in P1 and 34·6% in P3. 70·3% of responders felt that not enough was done for staff wellbeing. The median anxiety score decreased from P1 (10(range 5-17)) to P3 (8(range 4-16)) p=0·031. Under 30-year-olds’ depression and PTSD scores increased from P1 to P3 (depression: P1 7(1-11), P3 8(3-14), p=0·048, PTSD: P1 4(0-7) peak 3 5(2-9), p=0·037). Several groups showed a decrease in anxiety scores from P1 to P3 including; over 30-year-olds (P1 10(5-17), P3 7(3-15) p=0·002), BME responders (P1 8(3·75-15) P3 6·5(1-12) p=0·006), AHP (P1 14(7-19), P3 11(5-19) p=0·005), ITU workers (P1 15(8-18·25) P3 12(5·75-18·25) p=0·004), and those who were redeployed (P1 8(5-18·25), P3 5(2-14·75), p=0·032). Conclusion: We have observed changes in mental health symptoms within the study population as the peaks of the pandemic continue. With the majority of responders reporting they felt not enough had been done for their wellbeing support - and of those who used the wellbeing services only around 1/3 felt they were useful - we hope that this paper can help inform wellbeing provision and identify groups at higher risk of developing mental health symptoms.

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Maupin, Julie, et Dr Michael Mamoun. DTPH56-06-T-0004 Plastic Pipe Failure, Risk, and Threat Analysis. Chantilly, Virginia : Pipeline Research Council International, Inc. (PRCI), mars 2006. http://dx.doi.org/10.55274/r0012119.

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Reports, publications, papers, and databases were reviewed to better define risks and threats to plastic gas distribution piping. Failure modes were described for plastic PE piping with the most significant being slow crack growth (SCG). Short-term mechanical tests such as tensile, quick burst, melt index, and density tests did not show a correlation with a material's susceptibility to SCG failure. The bend-back test was able to visually identify 1971 low-ductile inner wall materials. PENT test failure times were reported for materials manufactured during the period1972-1985. The PENT test did not show correlations with the material's susceptibility to SCG failure for these materials. Life expectancy was determined to be a key measure of the susceptibility of PE gas pipe materials to SCG field failures. Long-term hydrostatic stress-rupture data combined with the Rate Process Method or with the Bi-Directional Shift Functions predicted the remaining life expectancy of several PE materials at 60�F average field temperature under varying loading conditions. Data showed rock impingement loads and pipe squeeze-offs can result in the greatest reduction in remaining life expectancy. Lower operating field temperatures and pressures significantly increased the predicted remaining life expectancy of PE materials. Fifty-five PE pipe samples that failed in field service were examined in the laboratory to identify the root cause of the failures. Eight of the samples underwent in-depth analysis, which included density and melts index tests and differential scanning calorimetry, infrared spectroscopy, and microscopic examination of the fracture surfaces. The samples were combined with another set of additional data resulting in 45 material, 36 procedural, 12 quality control, and 7 miscellaneous failures. A separate categorization method attributed a total of 321 failures to their respective pipe/component, with most occurring at joints. RCP in large diameter PE materials was investigated through laboratory testing. Critical pressure was determined for 6 pipe materials. The critical temperature was determined for 3 materials.

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