Bibliographies thématiques / 291.3/7

Littérature scientifique sur le sujet « 291.3/7 »

Auteur : Grafiati
Publié le 26 juillet 2024
Mis à jour le 27 juillet 2024

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Articles de revues sur le sujet "291.3/7"

1

Kumar, Lalit, et Puneet Utreja. « Oleic Acid Vesicles for Transdermal Delivery of Propranolol Hydrochloride : Development and Characterization ». Current Drug Therapy 15, no 3 (14 octobre 2020) : 238–48. http://dx.doi.org/10.2174/1574885514666190722164119.

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Background: Pharmaceutical scientists are exploring transdermal route for treatment of various systemic diseases nowadays. Transdermal nanocarrier systems show various advantages like bioavailability enhancement of drugs, avoidance of first pass hepatic metabolism, and reduction of dosing frequency of bioactive therapeutic molecules. Objective: The objective of the present research work was to encapsulate Propranolol hydrochloride into oleic acid vesicles and carry out in-vitro and in-vivo evaluation of oleic acid vesicular gel containing Propranolol hydrochloride. Method: Propranol hydrochloride loaded oleic acid vesicles were prepared by exploring thin film hydration method. Developed vesicles were evaluated for morphology, size, zeta potential and polydispersity index (PDI). Thermal behavior of drug loaded vesicles was checked using differential scanning calorimetry (DSC) and depth of skin penetration was determined using confocal laser scanning microscopy (CLSM). Oleic acid vesicles dispersed in Carbopol 934R gel were subjected to in-vivo evaluation in male Sprague Dawley rats through measurement of plasma concentration and tissue distribution of Propranolol hydrochloride. Results: Optimized formulation having oleic acid : Propranol hydrochloride in the ratio 7 : 3 showed highest entrapment (56.1 ± 0.7%), acceptable size (291.3 ± 2.2 nm), the optimum value of PDI (0.219 ± 0.043) and zeta potential (-27.13 ± 0.25 mV). The results of DSC analysis showed effective encapsulation of drug inside the vesicles and CLSM analysis revealed penetration of vesicles upto stratum spinosum layer of skin. The results of in-vivo study revealed capability of vesicular gel to prolong the release of Propranolol hydrochloride upto 24 h with a Cmax value of 83.6 ± 3.0 ng/mL which was higher compared to the marketed tablet of Propranolol hydrochloride [InderalR (40 mg), Abbott India Ltd.] (45.6 ± 3.1 ng/mL). Tissue distribution studies revealed higher percentage of Propranolol hydrochloride in various organs after 24 h of administration of vesicular gel compared to marketed tablet. Conclusion: Developed oleic acid vesicular gel could be effective to reduce dosing frequency and avoid side effects of oral Propranol hydrochloride.
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Rachtanapun, Pornchai, Dheerawan Boonyawan, Rafael A. Auras et Gopinath Kasi. « Effect of Water-Resistant Properties of Kraft Paper (KP) Using Sulfur Hexafluoride (SF6) Plasma Coating ». Polymers 14, no 18 (10 septembre 2022) : 3796. http://dx.doi.org/10.3390/polym14183796.

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Sulfur hexafluoride (SF6) plasma at different pressures, powers, and times was used to treat Kraft paper (KP) to enhance its water resistance. The KP was treated with SF6 plasma from 20–300 mTorr of pressure at powers from 25–75 Watts and treatment times from 1–30 min at 13.56 MHz. The prepared papers were characterized by contact angle measurement and water absorption. The selected optimum condition for the plasma-treated KP was 200 mTorr at 50 Watts for 5 min. Advancement with the change in treatment times (3, 5, and 7 min) on the physical and mechanical properties, water resistance, and morphology of KP with SF6 plasma at 200 mTorr and 50 Watts was evaluated. The changes in the chemical compositions of the plasma-treated papers were analyzed with an XPS analysis. The treatment times of 0, 3, 5, and 7 min revealed fluorine/carbon (F/C) atomic concentration percentages at 0.00/72.70, 40.48/40.97, 40.18/37.95, and 45.72/39.48, respectively. The XPS spectra showed three newly raised peaks at 289.7~289.8, 291.5~291.7, and 293.4~293.6 eV in the 3, 5, and 7 min plasma-treated KPs belonging to the CF, CF2, and CF3 moieties. The 5 min plasma-treated paper promoted a better interaction between the SF6 plasma and the paper yielded by the F atoms. As the treatment time for the treated KPs increased, the contact angle, water absorption time, and Cobb test values increased. However, the thickness and tensile strength did not show remarkable changes. The SEM images revealed that, as the treatment time increased, the surface roughness of the plasma-treated KPs also increased, leading to improved water resistance properties. Overall, the SF6 plasma treatment modified the surface at the nano-layer range, creating super-hydrophobicity surfaces.
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Agha, Amar, Diarmuid Smith, Francis Finucane, Mark Sherlock, Andrew Morris, Peter Baylis et Christopher J. Thompson. « Attenuation of vasopressin-induced antidiuresis in poorly controlled type 2 diabetes ». American Journal of Physiology-Endocrinology and Metabolism 287, no 6 (décembre 2004) : E1100—E1106. http://dx.doi.org/10.1152/ajpendo.00214.2004.

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Renal resistance to vasopressin has been demonstrated in type 1 diabetes and in type 2 diabetes with nephropathy. However, renal response to vasopressin in type 2 diabetes without nephropathy has not been studied. We studied 10 subjects with poorly controlled type 2 diabetes (PCDS; Hb A1c >9%), 10 subjects with well-controlled type 2 diabetes (WCDS; Hb A1c <7%), and 10 matched nondiabetic control subjects (NDCS) during a euglycemic 8-h water deprivation test. None of the subjects had nephropathy. Water deprivation caused similar rises in plasma vasopressin concentrations in all three groups, but the rise in urine osmolality in PCDS (280.3 ± 49.7 to 594.4 ± 88.5 mosmol/kgH2O) was lower than in WCDS (360.7 ± 142.8 to 794.1 ± 77.3 mosmol/kgH2O, P < 0.001) or NDCS (336.0 ± 123.3 to 786.5 ± 63.3 mosmol/kgH2O, P = 0.019). Total urine output was higher in the PCDS than in WCDS and NDCS ( P < 0.05). Linear regression analysis showed that, in PCDS, the osmotic thresholds for thirst (291.9 ± 4.6 mosmol/kgH2O) and vasopressin release (291.1 ± 2.9 mosmol/kgH2O) were higher compared with WCDS (286.6 ± 1.8 and 286.0 ± 3.6 mosmol/kgH2O, respectively) and NDCS (286.0 ± 2.4 and 284.1 ± 4.7 mosmol/kgH2O, respectively) (between groups P < 0.001 for both variables). Under conditions of euglycemia, PCDS have impaired renal response to vasopressin and elevated osmotic threshold for thirst and vasopressin release in response to dehydration. Under conditions of chronic hyperglycemia, these abnormalities may significantly contribute to the development of dehydration in PCDS.
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Sun, Xiao-Juan. « Crystal structure of catena-poly[(μ2-2,5-di(pyridin-3-yl)-1,3,4-thiadiazole-κ2N:N′)-bis(2,5-di(pyridin-3-yl)-1,3,4-thiadiazole-κ1N)-bis(thiocyanato-κ1N)cobalt(II)], C38H24CoN14S5 ». Zeitschrift für Kristallographie - New Crystal Structures 234, no 1 (19 décembre 2018) : 39–40. http://dx.doi.org/10.1515/ncrs-2018-0118.

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AbstractC38H24CoN14S5, triclinic, P1̄, a = 10.6306(6) Å, b = 13.1604(5) Å, c = 15.1858(7) Å, α = 81.039(4) Å, β = 82.393(4) Å, γ = 66.803(4) Å, V = 1923.04(17) Å3, Z = 2, Rgt(F) = 0.0420, wRref(F2) = 0.0882, T = 291.6(7) K.
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Hong, Dong-Feng, Wen-Bo Guo et Wei-Dong Yin. « Crystal structure of poly[(μ2-2-carboxy-5-nitroisophthalato-κ2O:O′)-(μ2-4-((1H-imidazol-1-yl)methyl)pyridine-κ2N:N′)zinc(II)], C18H12N4O8Zn ». Zeitschrift für Kristallographie - New Crystal Structures 233, no 6 (27 novembre 2018) : 1035–36. http://dx.doi.org/10.1515/ncrs-2018-0156.

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Li, Jun-Xia, et Zhong-Xiang Du. « The crystal structure of catena-poly[(μ2-4,4′-dipyridine-κ2N,N′)-bis(3,5,6-trichloropyridine-2-oxyacetato-κO)-bis(ethanol-κO)nickel(II)], C28H26Cl6N4NiO8 ». Zeitschrift für Kristallographie - New Crystal Structures 235, no 4 (25 juin 2020) : 887–90. http://dx.doi.org/10.1515/ncrs-2020-0083.

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AbstractC28H26Cl6N4NiO8, monoclinic, I2/a (no. 15), a = 15.7577(10) Å, b = 12.6174(7) Å, c = 16.7333(10) Å, β = 99.609(6)Å, V = 3280.3(3) Å3, Z = 4, Rgt(F) = 0.0674, wRref(F2) = 0.1665, T = 291.2(3) K.
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Haldar, Sumanto, Sze Lee, Jun Tan, Siok Chia, Christiani Henry et Eric Chan. « Dose-Dependent Increase in Unconjugated Cinnamic Acid Concentration in Plasma Following Acute Consumption of Polyphenol Rich Curry in the Polyspice Study ». Nutrients 10, no 7 (20 juillet 2018) : 934. http://dx.doi.org/10.3390/nu10070934.

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Spices that are rich in polyphenols are metabolized to a convergent group of phenolic/aromatic acids. We conducted a dose-exposure nutrikinetic study to investigate associations between mixed spices intake and plasma concentrations of selected, unconjugated phenolic/aromatic acids. In a randomized crossover study, 17 Chinese males consumed a curry meal containing 0 g, 6 g, and 12 g of mixed spices. Postprandial blood was drawn up to 7 h at regular intervals and plasma phenolic/aromatic acids were quantified via liquid chromatography tandem mass spectrometry (LC-MS/MS). Cinnamic acid (CNA, p < 0.0001) and phenylacetic acid (PAA, p < 0.0005) concentrations were significantly increased with mixed spices consumption, although none of the other measured phenolic/aromatic acids differ significantly between treatments. CNA displayed a high dose-exposure association (R2 > 0.8, p < 0.0001). The adjusted mean area under the plasma concentration-time curve until 7 h (AUC0–7 h) for CNA during the 3 increasing doses were 8.4 ± 3.4, 376.1 ± 104.7 and 875.7 ± 291.9 nM.h respectively. Plasma CNA concentration may be used as a biomarker of spice intake.
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Arifin, Zainul, Irvin Dayadi et Cristianus Renaldy. « Uji Ketahanan Api Kayu Sengon (Paraserianthes falcataria (L.) Nielsen) yang Diawetkan dengan Bahan Pengawet Natrium Silikat (Na2SiO3) ». ULIN : Jurnal Hutan Tropis 4, no 2 (9 septembre 2020) : 92. http://dx.doi.org/10.32522/ujht.v4i2.4251.

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The results of this study indicate that the average value of air dry moisture content of sengon wood is 14.081%, the air dry density is 0.326 g/m3 and oven dry density is 0.295 g/m3. The highest average retention value was at 3 days immersion with a concentration of 7% i.e. 16.161 kg/m3 and the lowest was at 1 day immersion with a concentration of 3% i.e. 5.161 kg/m3. The highest value of burn intensity at 2 days immersion with a 3% concentration i.e. 16.249% and the lowest at 1 day immersion with a concentration of 7% i.e. 6.025%. Preservation of sengon wood using natrium silicate at a concentration of 3%, 5% and 7% and immersion for 1 day, 2 days and 3 days is less effective in holding the fire rate, because the value is still below the ASTM E69 standard (2002) i.e. 7.5. The effective test of preservative (W) obtained the highest value of burn intensity at 1 day immersion with a concentration of 7% i.e. 7,490 and the lowest value at 2 days of immersion with a concentration of 3%, i.e. 3,231. The maximum temperature ranges from 206.0-291.2°C and the cooking time ranges from 206.1-607.8 seconds.
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Carpenter, Chelsea A., Maggi C. Miller, Xuemei Sui et Delia S. West. « Weight Status and Sedentary Behavior of Alzheimer's Disease Caregivers ». American Journal of Health Behavior 44, no 1 (1 janvier 2020) : 3–12. http://dx.doi.org/10.5993/ajhb.44.1.1.

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Objectives: In this study, we sought to characterize the weight status, sedentary behavior, and physical activity of caregivers of individuals with Alzheimer's disease. Methods: In 2014, we surveyed caregivers of individuals with Alzheimer's disease from the South Carolina Alzheimer's Disease Registry (N = 47) about their personal health behaviors. Additionally, a subset of individuals (N = 14) wore an accelerometer for 7 days. Results: Caregivers (N = 47) were mostly overweight or obese (85%) and self-reported a daily average sedentary time of 246.5 ± 203.0 minutes and 455.8 ± 291.4 minutes, as measured by 2 questionnaires. Objective measures indicated that persons spent an average of 769.4 ± 167.6 minutes per day (77.8% of their waking day) engaged in sedentary behavior. Conclusion: Given the negative health outcomes associated with both obesity and sedentary behavior, this is a vulnerable population that likely would benefit from interventions focused on weight management and reducing sedentary behavior.
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Chen, Siyuan, Jianshe Ma, Xianqin Wang et Quan Zhou. « Simultaneous Determination of Ropivacaine and 3-Hydroxy Ropivacaine in Cerebrospinal Fluid by UPLC-MS/MS ». BioMed Research International 2020 (4 décembre 2020) : 1–6. http://dx.doi.org/10.1155/2020/8844866.

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In this paper, a UPLC-MS/MS method was developed for the determination of ropivacaine and its metabolite 3-hydroxy ropivacaine in cerebrospinal fluid. The cerebrospinal fluid was processed by ethyl acetate liquid-liquid extraction. The multiple reaction monitoring (MRM) mode was used for quantitative analysis by monitoring the transitions of m/z 275.3 → 126.2 for ropivacaine, m/z 291.0 → 126.0 for 3-hydroxy ropivacaine, and m/z 290.2 → 198.2 for the internal standard. Standard curves for ropivacaine and 3-hydroxy ropivacaine in cerebrospinal fluid were conducted over the concentration range of 0.2–2000 ng/mL, demonstrating excellent linearity, and the lower limit of quantification was 0.2 ng/mL. The intraday precision of ropivacaine and 3-hydroxy ropivacaine was less than 11%, while the interday precision was less than 7%. The accuracy ranged between 87% and 107%, the average extraction efficiency was higher than 79%, and the matrix effect was between 89% and 98%. The developed method was then applied to a case of suspected poisoning of ropivacaine.
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Livres sur le sujet "291.3/7"

1

Magic Mushrooms in Religion and Alchemy. 2e éd. Park Street Press, 2002.

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Horapollo. Hieroglyphics of Horapollo Nilous. Franklin Classics, 2018.

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Horapollo. Hieroglyphics of Horapollo Nilous. Franklin Classics Trade Press, 2018.

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Horapollo. Horapollinis Niloi Hieroglyphica. Creative Media Partners, LLC, 2023.

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Horapollo. Hieroglyphics of Horapollo Nilous. Franklin Classics, 2018.

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Disciplines of Faith : Studies in Religion, Politics and Patriarchy. Routledge, 2013.

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