Literatura académica sobre el tema "YAP/TEAD COMPLEX"
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Artículos de revistas sobre el tema "YAP/TEAD COMPLEX"
Pobbati, Ajaybabu V. y Brian P. Rubin. "Protein-Protein Interaction Disruptors of the YAP/TAZ-TEAD Transcriptional Complex". Molecules 25, n.º 24 (18 de diciembre de 2020): 6001. http://dx.doi.org/10.3390/molecules25246001.
Texto completoKim, Jisook, Seung Hyun Jung, Seon Yeong Han, Jihee Yoon, Minjeong Kim, Jooyun Byun, Heesun Moon et al. "Abstract 1614: Antitumor activity of novel and potent YAP/TAZ-TEAD inhibitorstargeting the Hippo pathway in solid tumors". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 1614. http://dx.doi.org/10.1158/1538-7445.am2023-1614.
Texto completoMoure, Casey J., Christopher Sondey, Mangeng Cheng, My Mansueto, Rafael Fernandez, Sebastian E. Schneider, Julia V. Ramirez et al. "Abstract 3938: Discovery of a novel small molecule inhibitor of the YAP1/TAZ-TEAD transcriptional complex". Cancer Research 82, n.º 12_Supplement (15 de junio de 2022): 3938. http://dx.doi.org/10.1158/1538-7445.am2022-3938.
Texto completoLi, Z., B. Zhao, P. Wang, F. Chen, Z. Dong, H. Yang, K. L. Guan y Y. Xu. "Structural insights into the YAP and TEAD complex". Genes & Development 24, n.º 3 (1 de febrero de 2010): 235–40. http://dx.doi.org/10.1101/gad.1865810.
Texto completoLauriola, Angela, Elisa Uliassi, Matteo Santucci, Maria Laura Bolognesi, Marco Mor, Laura Scalvini, Gian Marco Elisi et al. "Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library". Pharmaceutics 14, n.º 2 (10 de febrero de 2022): 391. http://dx.doi.org/10.3390/pharmaceutics14020391.
Texto completoSheldon, Caroline, Aaron Farley, Qing Ma, William T. Pu y Zhiqiang Lin. "Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development". Cells 11, n.º 18 (10 de septiembre de 2022): 2832. http://dx.doi.org/10.3390/cells11182832.
Texto completoKim, Eui Hyun y Seok-Gu Kang. "CSIG-25. DIFFERENTIAL YAP ACTIVITY IN HUMAN GLIOBLASTOMA TUMORSPHERES AS A POTENTIAL BIOMARKER". Neuro-Oncology 24, Supplement_7 (1 de noviembre de 2022): vii44. http://dx.doi.org/10.1093/neuonc/noac209.174.
Texto completoKim, Cho-Long, Yu-Su Shin, Sue-Hee Choi, Seroc Oh, Kyeongseob Kim, Han-Sol Jeong y Jung-Soon Mo. "Extracts of Perilla frutescens var. Acuta (Odash.) Kudo Leaves Have Antitumor Effects on Breast Cancer Cells by Suppressing YAP Activity". Evidence-Based Complementary and Alternative Medicine 2021 (15 de febrero de 2021): 1–13. http://dx.doi.org/10.1155/2021/5619761.
Texto completode Andrade, Leonardo Guedes, Valério Marques Portela, Esdras Corrêa Dos Santos, Karine de Vargas Aires, Rogério Ferreira, Daniele Missio, Zigomar da Silva et al. "FSH Regulates YAP-TEAD Transcriptional Activity in Bovine Granulosa Cells to Allow the Future Dominant Follicle to Exert Its Augmented Estrogenic Capacity". International Journal of Molecular Sciences 23, n.º 22 (16 de noviembre de 2022): 14160. http://dx.doi.org/10.3390/ijms232214160.
Texto completoCheng, Wen-Chih, Osnat Bohana-Kashtan, Sebastien Morisot, Nailing Zhang, Qian Chen, Duojia Pan y Curt I. Civin. "The YAP Transcriptional Co-Activator Is Not Required for Mouse Hematopoiesis, at Steady State or After 5FU Treatment." Blood 116, n.º 21 (19 de noviembre de 2010): 1592. http://dx.doi.org/10.1182/blood.v116.21.1592.1592.
Texto completoTesis sobre el tema "YAP/TEAD COMPLEX"
Gibault, Floriane. "Conception, synthèse et évaluation d’inhibiteurs du complexe protéique YAP-TEAD à visée anticancéreuse". Thesis, Lille 1, 2017. http://www.theses.fr/2017LIL10097.
Texto completoThe Hippo pathway, firstly described in Drosophila and highly conserved in mammals, has been demonstrated to play a crucial role in the organ size control. This kinase cascade regulates the phosphorylation of the downstream effector YAP (or its paralogue TAZ), a transcriptional coactivator with oncogenic activity. Its function is mediated by its nuclear translocation and interaction with the transcriptional factor TEAD, to form YAP-TEAD complex which activates the genes expression in charge of cell proliferation triggering organ growth. Overexpression of YAP/TAZ/TEAD protein in several cancers disrupts the Hippo pathway balance and urges on YAP-TEAD complex formation causing excessive proliferation and cancer development. Inhibiting this protein-protein interaction is thus a promising therapeutic target for the design of new anti-cancer drugs. In this goal, the laboratory has considered two strategies. The first one consists in targeting the YAP protein by synthesizing dipyrrins, representing Verteporfin fragments to define the minimal requirement yielding the expected biological activity. A second approach involves synthesizing TEAD ligands able to fit in specific interface 3. Based on molecular modeling, a triazole scaffold family was optimized to establish structure-activity relationship. Thanks to the biological and binding tests development, synthesized molecules evaluation is still in progress and the present first results have already allowed identifying a promising compound
SINGH, SIMRAN. "EXPLORING NATURAL COMPOUNDS TARGETING THE HIPPO PATHWAY FOR POTENTIAL TREATMENT OF MENINGIOMA". Thesis, 2023. http://dspace.dtu.ac.in:8080/jspui/handle/repository/19944.
Texto completoLibros sobre el tema "YAP/TEAD COMPLEX"
Cappuccio, Massimiliano L., ed. Handbook of Embodied Cognition and Sport Psychology. The MIT Press, 2019. http://dx.doi.org/10.7551/mitpress/10764.001.0001.
Texto completoCapítulos de libros sobre el tema "YAP/TEAD COMPLEX"
Hsu, Wynne, Mong Li Lee y Junmei Wang. "Mining Spatio-Temporal Graph Patterns". En Temporal and Spatio-Temporal Data Mining, 227–61. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-387-6.ch011.
Texto completoActas de conferencias sobre el tema "YAP/TEAD COMPLEX"
Velazquez, Antonio y R. Andrew Swartz. "Gyroscopic Effects of Horizontal Axis Wind Turbines Using Stochastic Aeroelasticity via Spinning Finite Elements". En ASME 2012 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/smasis2012-8118.
Texto completoDurali, Mohammad y Mohammad Mahdi Jalili. "Time Saving Simulation of Long Train Derailment". En ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-66885.
Texto completoAlexandre, Armando, Raffaello Antonutti, Theo Gentils, Laurent Mutricy y Pierre Weyne. "Simplified Aerodynamic Loading Model for Non-Production Conditions for Floating Wind Systems Design". En ASME 2021 3rd International Offshore Wind Technical Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/iowtc2021-3516.
Texto completoRuiz Toledo, Maria Mercedes. "Propuesta de material didáctico desde el diseño visual acotado en la inclusión y el entorno educativo infantil autista del centro Neurokids". En Encuentro de investigación formativa en Diseño – Semilleros y Grupos de investigación RAD 2019. Pasto, Colombia: Red Académica de Diseño - RAD, 2019. http://dx.doi.org/10.53972/rad.eifd.2019.2.5.
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