Bibliografías temáticas / WF.143

Literatura académica sobre el tema "WF.143"

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Publicado: 13 de abril de 2024

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Artículos de revistas sobre el tema "WF.143"

Garg, S., B. Chewning, S. Gomez y C. Bartels. "POS1126 THERAPEUTIC RANGE OF HYDROXYCHLOROQUINE BLOOD LEVELS CAN REDUCE ODDS OF HIGH LUPUS DISEASE ACTIVITY". Annals of the Rheumatic Diseases 82, Suppl 1 (30 de mayo de 2023): 890.3–891. http://dx.doi.org/10.1136/annrheumdis-2023-eular.960.

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BackgroundHydroxychloroquine (HCQ) is the cornerstone of systemic lupus erythematous (SLE or lupus) treatment, yet, the optimal dosing of HCQ in SLE is unknown. Reducing HCQ dose to 5 mg/kg to limit toxicity, as suggested by the American Academy of Ophthalmologists (AAO),(1) also predicts increased flares.(2) One study showed six-fold higher risk of severe SLE flares in patients receiving AAO recommended HCQ dosing.(2) Therefore, establishing effective therapeutic ranges of HCQ blood levels may provide an opportunity to individualize HCQ dosing to maximize efficacy and limit toxicity.ObjectivesThe objective of this study was to examine the association of HCQ blood levels with high lupus disease activity (HDA) in a prospective SLE cohort.MethodsThis cross-sectional study measured HCQ blood levels in unique SLE visits using liquid chromatography-tandem mass spectrometry. HCQ blood levels and SLE disease activity index (SLEDAI) scores were measured on the day of the visit for each patient. High lupus disease activity (HDA) was defined as SLEDAI scores of ≥6.(3) To identify significant HCQ blood levels that determined lower odds of HDA, we examined associations between HDA and every 50-100 ng/ml increase in HCQ blood levels starting at 100 ng/ml through 1500 ng/ml. Other factors that can affect HCQ levels, such as patient-reported adherence, kidney function, and HCQ dose and timing, were included in multivariable models.ResultsAmong 143 SLE patients in whom HCQ blood levels were measured, 92% were women and 32% were of non-White race or Hispanic ethnicity. HDA was noted in 18% of patients. We noted a 75% reduction in the odds of HDA first at HCQ blood levels of ≥750 ng/ml (Adjusted OR 0.25, 95% CIs 0.066-0.89, p-value = 0.035; Figure 1). This effect peaked with HCQ blood levels ≥1100 ng/ml with 93% lower odds of HDA at this level (Adjusted OR 0.07, 95% CIs 0.005-0.61, p-value = 0.038; Figure 1). Interestingly, levels of 1150 ng/ml or higher did not further reduce the odds of HDA (Figure 1).Additionally, we noted that female sex was associated with 88% lower odds of HDA (Table 1), while other factors including HCQ dose or timing were not associated with HDA (Table 1).ConclusionWe report an effective therapeutic range of HCQ blood levels, 750-1100 ng/ml, that significantly correlated with reduced risk of high lupus disease activity (HDA) by 75-93% in patients with SLE. These findings could guide clinicians to individualize HCQ doses to achieve target blood levels within this range to maximize efficacy, while balancing safety.References[1]Marmor MF, Kellner U, Lai TYY, Melles RB, Mieler WF. Recommendations on screening for chloroquine and hydroxychloroquine retinopathy (2016 revision). Ophthalmology 2016;123:1386–1394.[2)] Jorge AM, Mancini C, Zhou B, et al. Hydroxychloroquine Dose per Ophthalmology Guidelines and the Risk of Systemic Lupus Erythematosus Flares.JAMA.2022;328(14):1458–1460.[3]Arora, S., Isenberg, D.A. and Castrejon, I. (2020), Measures of Adult Systemic Lupus Erythematosus: Disease Activity and Damage. Arthritis Care Res, 72: 27-46.Acknowledgments.The UW SLE Cohort is supported by the DOM and ICTR at UW-Madison.Figure 1.Effective range of HCQ levels (shaded box) that reduces odds of high SLE disease activity. Significant adjusted odds ratio shown in bold.Table 1.Factors Associated with High SLE Disease Activity (SLEDAI ≥6), Multivariable ModelVariablesAdjusted Odds Ratio (95% CIs)p-valueAge (per 10 years increase)0.99 (1.03, 9.6)0.89Female0.11 (0.013, 0.83)0.03Non-White race & Hispanic ethnicity0.75 (0.23, 2.3)0.61Weight (per 5 kg increase)0.97 (0.93-1.01)0.13CKD stage ≥21.077 (0.29, 3.9)0.91HCQ total dose200 mg dailyref300 mg/d1.8 (0.29, 22)0.43400 mg daily3.0 (0.49, 22)0.25AAO-Guideline based dose, ≤5 mg/kg/day1.4 (0.2, 12)0.73HCQ blood levels ≥1100 ng/ml0.07 (0.004, 0.45)0.02Patient-reported adherence ≥80%0.57 (0.16, 2.1)0.38Social Determinants of Health, Present3.2 (0.86, 12)0.99HCQ dose timing<4 hoursref4-6 hours3.3 (0.15, 153)0.486-8 hours2.03 (0.1, 81)0.66>8 hours0.15 (0.08, 60)0.80Disclosure of InterestsShivani Garg: None declared, Betty Chewning: None declared, Shelby Gomez: None declared, Christie Bartels Grant/research support from: Received an independent learning grant from Pfizer for a different research project.

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Gonçalves, Gabriela Sumie Yaguinuma, Tayna Natsumi Takakura, Anderson Catelan, Rosalinda Tanuri Zaninotto Venturim, Carolina dos Santos Santinoni y Christine Men Martins. "Tratar ou extrair? Tratamento de lesão endoperiodontal, um relato de caso clínico". ARCHIVES OF HEALTH INVESTIGATION 9, n.º 6 (20 de abril de 2020): 535–40. http://dx.doi.org/10.21270/archi.v9i6.4814.

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Introdução: Lesões endoperiodontais são lesões originadas de produtos inflamatórios encontrados tanto em periodonto quanto em polpa. Tais lesões podem se originar devido a uma infecção pulpar ou periodontal. Visando o prognóstico favorável, é imprescindível o conhecimento da etiologia, realização do correto diagnóstico e elaboração do plano de tratamento que envolve o tratamento endodôntico precedido do tratamento periodontal. Objetivo: O propósito do presente trabalho foi de relatar um caso clínico de lesão endoperiodontal e o tratamento realizado. Relato de caso clínico: Paciente gênero feminino, 51 anos, compareceu à clínica com uma fístula na região do dente 46, procedeu-se com exame radiográfico, rastreamento de fístula, testes endodônticos e avaliação periodontal. Foi diagnosticada lesão endoperiodontal. Executou-se, então, o tratamento endodôntico em sessões múltiplas, utilizando hidróxido de cálcio como medicação intracanal e o tratamento periodontal concomitante; finalizou-se endodontia obturando-se os canais radiculares. Conclusão: Observou-se, no controle, que a associação de tratamentos foi eficaz e houve melhora significativa do quadro, constatando-se silêncio clínico e sucesso do tratamento. Realizar o tratamento conservador a despeito da exodontia foi a melhor escolha para a paciente. Descritores: Endodontia; Periodontia; Polpa Dentária; Periodonto. Referências Sunitha VR, Emmadi P, Namasivayam A, Thyegarajan R, Rajaraman V. The periodontal - endodontic continuum A review. J Conserv Dent. 2008;11(2):54-62. Betancourt P, Elgueta R, Fuentes R. Treatment of endo-periodontal lesion using leukocyte-platelet-rich fibrin - a case report. Colomb Med. 2017;48(4):204-7. Lopes HP, Siqueira JF. Endodontia: Biologia e Técnica. Rio de Janeiro: Medsi-Guanabara Koogan; 2015. Lindhe J, Karring T, Lang NP. Tratado de periodontia clínica e implantologia oral. Rio de Janeiro: Guanabara Koogan; 2010. Anand V, Govila V, Gulati M. Endo-perio lesion part II (the treatment) - a review. 2012;3(1):10-6. Rotstein I, Simon JH. Diagnosis, prognosis and decision-making in the treatment of combined periodontal-endodontic lesions. J Periodontol. 2004;34:165-203. Parolia A, Gait TC, Porto ICCM, Mala K. Endo-perio lesion: a dilemma from 19th until 21st century. J Interdisp Dent. 2013;3(1):2-11. Kim E, Song JS, Jung IY, Lee SJ, Kim S. Prospective clinical study evaluating endodontic microsurgery outcomes for cases with lesions of endodontic origin compared with cases with lesions of combined periodontal-endodontic origin. J Endod. 2008;34(5):546-51. Heasman PA. An endodontic conundrum: the association between pulpal infection and periodontal disease. Br Dent J. 2014;216(6):275-9. Schmidt JC, Walter C, Amato M, Weiger R. Treatment of periodontal-endodontic lesions--a systematic review. J Clin Periodontol. 2014; 41(8):779-90. Jivoinovici R, Suciu I, Dimitriu B, Perlea P, Bartok R, Malita M, Ionescu C. Endo-periodontal lesion--endodontic approach. J Med Life. 2014;7(4):542-44. Estrela C. Endodontia laboratorial e clínica, Série Abeno: Odontologia Essencial - Parte Clínica. São Paulo: Artes Médicas; 2013. Vera J, Siqueira JF Jr, Ricucci D, Loghin S, Fernández N, Flores B et al. One-versus two-visit endodontic treatment of teeth with apical periodontitis: a histobacteriologic study. J Endod. 2012;38(8):1040-52. Mohammadi Z, Dummer PMH. Properties and applications of calcium hydroxide in endodontics and dental traumatology. Inter Endod J. 2011;44(8):697-730. Batista VES, Olian DA, Mori GG. Diffusion of hydroxyl ions from calcium hydroxide and aloe vera pastes. Braz Dent J. 2014;25(3):212-16. Pereira TC, da Silva Munhoz Vasconcelos LR, Graeff MSZ, Ribeiro MCM, Duarte MAH, de Andrade FB. Intratubular decontamination ability and physicochemical properties of calcium hydroxidepastes. Clin Oral Investig. 2019;23(3):1253-62. Andolfatto C, da Silva GF, Cornélio AL, Guerreiro-Tanomaru JM, Tanomaru-Filho M, Faria G, Bonetti-Filho I, Cerri PS. Biocompatibility of intracanal medications based on calcium hydroxide. ISRN Dent. 2012;2012:904963. Duque TM, Prado M, Herrera DR, Gomes BPFA. Periodontal and endodontic infectious/inflammatory profile in primary periodontal lesions with secondary endodontic involvement after a calcium hydroxide-based intracanal medication. Clin Oral Investig. 2019;23(1):53-63. Kim D, Kim E. Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part I. In vitro studies. Restor Dent Endod. 2014; 39(4):241-52. Adl A, Motamedifar M, Shams MS, Mirzaie A. Clinical investigation of the effect of calcium hydroxide intracanal dressing on bacterial lipopolysaccharide reduction from infected root canals. Aust Endod J. 2015;41(1):12-6. Hilton TJ, Ferracane JL, Mancl L; Northwest Practice-based Research Collaborative in Evidence-based Dentistry (NWP). Comparison of CaOH with MTA for direct pulp capping: a PBRN randomized clinical trial. J Dent Res. 2013;92(7 Suppl):16S-22S. Labban N, Yassen GH, Windsor LJ, Platt JA. The direct cytotoxic effects of medicaments used in endodontic regeneration on human dental pulp cells. Dent Traumatol. 2014;30(6):429-34. McIntyre PW, Wu JL, Kolte R, Zhang R, Gregory RL, Bruzzaniti A, Yassen GH. The antimicrobial properties, cytotoxicity, and differentiation potential of double antibiotic intracanal medicaments loaded into hydrogel system. Clin Oral Investig. 2019;23(3):1051-59. Bergenholtz, G., Hasselgren, G. Endodontics and periodontics. In: Lindhe, K., Karring, T., Lang, N. Clinical periodontology and implant dentistry. Copenhagen:Munksgaard; 2015. Harrington GW, Steiner DR, Ammons WF. The periodontal-endodontic controversy. Periodontol 2000. 2002;30:123-30. Fernandes LA, Martins TM, Almeida JM, Nagata MJ, Theodoro LH, Garcia VG, Bosco AF. Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats. J Appl Oral Sci. 2010;18(6):635-40. Storrer CM, Bordin GM, Pereira TT. How to diagnose and treat periodontal endodontic lesions? 2012;9(4):427-33. Verma PK, Srivastava R, Gupta KK, Srivastava A. Combined endodontic periodontal lesions: A clinical dilema. J Interdiscip Dent. 2011;1(2):119-24. Oh SL, Fouad AF, Park SH. Treatment strategy for guided tissue regeneration in combined endodontic-periodontal lesions: case report and review. J Endod. 2009;35(10):1331-36. Malli R, Lele P, Vishakha. Guided tissue regeneration in communicating periodontal and endodontic lesions - a hope for the hopeless. J Indian Soc Periodontol. 2011;15(4):410-13. Ghezzi C, Virzì M, Schupbach P, Broccaioli A, Simion M. Treatment of combined endodontic-periodontic lesions using guided tissue regeneration: clinical case and histology. Int J Periodontics Restorative Dent. 2012;32(4):433-9. Sun J, Liu Q. [Bio-Oss collagen bone grafting in the treatment of endodontic-periodontic lesion]. Nan Fang Yi Ke Da Xue Xue Bao. 2009;29(9):1905-6. Sharma R, Hegde V, Siddharth M, Hegde R, Manchanda G, Agarwal P. Endodontic-periodontal microsurgery for combined endodontic-periodontal lesions: An overview. J Conserv Dent. 2014;17(6):510-16. Li Y, Wang X, Xu J, Zhou X, Xie K. [The clinical study on the use of diode laser irradiation in the treatment of periodontal-endodontic combined lesions]. Hua Xi Kou Qiang Yi Xue Za Zhi. 2012;30(2):161-64, 168. Narang S, Narang A, Gupta R. A sequential approach in treatment of perio-endo lesion. J Indian Soc Periodontol. 2011;15(2):177-80. Pereira AL, Orzechowski PR, Filho SB, Cortelli JR. Subepithelial connective tissue graft: an alternative application for treating endoperiodontal lesions. Gen Dent. 2013;61(2):50-3. Yoneda M, Motooka N, Naito T, Maeda K, Hirofuji T. Resolution of furcation bone loss after non-surgical root canal treatment: application of a peptidase-detection kit for treatment of type I endoperiodontal lesion. J Oral Sci. 2005; 47(3):143-47. Shenoy N, Shenoy A. Endo-perio lesions: diagnosis and clinical considerations. Indian J Dent Res. 2010;21(4):579-85. Gerritsen AE, Allen PF, Witter DJ, Bronkhorst EM, Creugers NH. Tooth loss and oral health-related quality of life: a systematic review and meta-analysis. Health Qual Life Outcomes. 2010;8:126.

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Pasha, Imran, Abdul Basit, Muhammad Ahsin y Farah Ahmad. "Probing nutritional and functional properties of salted noodles supplemented with ripen Banana peel powder". Food Production, Processing and Nutrition 4, n.º 1 (1 de septiembre de 2022). http://dx.doi.org/10.1186/s43014-022-00100-5.

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AbstractBanana peel is appreciated for higher dietary fiber, phenolics, flavonoid contents, and minerals (particularly iron, calcium, and potassium), despite being a waste product. After drying, it can be processed into powder/flour to be combined with wheat flour (WF) for development of value-added products. In this study, we substituted WF with banana peel powder (BPP) at supplementation rates of 5, 10, and 15%, and evaluated their suitability to develop salted noodles. The results showed that the composite flour with 15% BPP had significantly higher protein, ash, and crude fiber content as compared to control. Higher antioxidant capacity was observed in composite flour noodles: total phenolics content (TPC), total flavonoid content (TFC), ferric reducing power (FRAP) and DPPH reducing power were increased up to 278, 260, 143 and 13 percent respectively in the noodles containing 15% BPP as compared to control (100% WF). On the other hand, values for viscosity decreased up to 22% with addition of BPP in WF. Furthermore, water absorption capacity and cooking losses were increased up to 15 and 13 percent respectively with 15% BPP incorporation in WF. Results for sensory evaluation demonstrated that noodles with 10% BPP scored highest for sensory profile. Graphical abstract

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Raviv-Moshe, Avia y Siwei Zhong. "Phases of surface defects in Scalar Field Theories". Journal of High Energy Physics 2023, n.º 8 (22 de agosto de 2023). http://dx.doi.org/10.1007/jhep08(2023)143.

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Abstract We study mass-type surface defects in a free scalar and Wilson-Fisher (WF) O(N) theories. We obtain exact results for the free scalar defect, including its RG flow and defect Weyl anomaly. We classify phases of such defects at the WF fixed point near four dimensions, whose perturbative RG flow is investigated. We propose an IR effective action for the non-perturbative regime and check its self-consistency.

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Sk, Farooq. "Journal Vol – 15 No -7, July 2020 Journal > Journal > Journal Vol – 15 No -7, July 2020 > Page 6 PERFORMANCE AND EMISSION CHARACTERISTICS OF GASOLINE-ETHANOL BLENDS ON PFI-SI ENGINE Authors: D.Vinay Kumar ,G.Samhita Priyadarsini,V.Jagadeesh Babu,Y.Sai Varun Teja, DOI NO: https://doi.org/10.26782/jmcms.2020.07.00051 admin July 26, 2020 Abstract: Alcohol based fuels can be produced from renewable energy sources and has the potential to reduce pollutant emissions due to their oxygenated nature. Lighter alcohols like ethanol and methanol are easily miscible with gasoline and by blending alcohols with gasoline; a part of conventional fuel can be replaced while contributing to fuel economy. Several researchers tested various ethanol blends on different engine test rigs and identified ethanol as one of the most promising ecofriendly fuels for spark ignition engine. Its properties high octane number, high latent heat of vaporization give better performance characteristics and reduces exhaust emissions compared to gasoline. This paper focuses on studying the effects of blending 50 of ethanol by volume with gasoline as it hardly needs engine modifications. Gasoline (E0) and E50 fuels were investigated experimentally on single-cylinder, four-stroke port fuel injection spark ignition engine by varying engine speed from 1500 rpm to 3500 rpm. Performance Characteristics like torque, brake power, specific fuel consumption, and volumetric efficiency and exhaust emissions such as HC, CO, CO2, NOx were studied.. Keywords: Ethanol,Emissions,Gasoline,Port fuel Injection, Refference: I Badrawada, I. G. G., and A. A. P. Susastriawan. “Influence of ethanol–gasoline blend on performance and emission of four-stroke spark ignition motorcycle.” Clean Technologies and Environmental Policy (2019): 1-6. II Doğan, Battal, et al. “The effect of ethanol-gasoline blends on performance and exhaust emissions of a spark ignition engine through exergy analysis.” Applied Thermal Engineering 120 (2017): 433-443. III Efemwenkiekie, U. Ka, et al. “Comparative Analysis of a Four Stroke Spark Ignition Engine Performance Using Local Ethanol and Gasoline Blends.” Procedia Manufacturing 35 (2019): 1079-1086. IV Galloni, E., F. Scala, and G. Fontana. “Influence of fuel bio-alcohol content on the performance of a turbo-charged, PFI, spark-ignition engine.” Energy 170 (2019): 85-92. V Hasan, Ahmad O., et al. “Impact of changing combustion chamber geometry on emissions, and combustion characteristics of a single cylinder SI (spark ignition) engine fueled with ethanol/gasoline blends.” Fuel 231 (2018): 197-203. VI Mourad, M., and K. Mahmoud. “Investigation into SI engine performance characteristics and emissions fuelled with ethanol/butanol-gasoline blends.” Renewable Energy 143 (2019): 762-771. VII Singh, Ripudaman, et al. “Influence of fuel injection strategies on efficiency and particulate emissions of gasoline and ethanol blends in a turbocharged multi-cylinder direct injection engine.” International Journal of Engine Research (2019): 1468087419838393. VIII Thakur, Amit Kumar, et al. “Progress in performance analysis of ethanol-gasoline blends on SI engine.” Renewable and Sustainable Energy Reviews 69 (2017): 324-340. View Download Journal Vol – 15 No -7, July 2020 CHARACTERIZATION OF MATERIALS FOR CUSTOMIZED AFO USING ADDITIVE MANUFACTURING Authors: Gamini Suresh,Nagarjuna Maguluri,Kunchala Balakrishna, DOI NO: https://doi.org/10.26782/jmcms.2020.07.00052 admin July 26, 2020 Abstract: Neurodegenerative conditions and compressed nerves often cause an abnormal foot drop that affects an individual gait and make it difficult to walk normally. Ankle Foot Orthosis (AFO) is the medical device which is recommended for the patients to improve the walking ability and decrease the risk of falls. Custom AFOs provide better fit, comfort and performance than pre-manufactured ones. The technique of 3D-printing is suitable for making custom AFOs. Fused deposition modelling (FDM) is a 3D-printing method for custom AFO applications with the desired resistance and material deposition rate. Generally, FDM is a thermal process; therefore materials thermal behaviour plays an important role in optimizing the performance of the printed parts. The objective of this study is to evaluate the thermal behaviour of PLA, ABS, nylon and WF-PLA filaments before manufacturing the AFO components using the FDM method. In the study, the sequence of testing materials provides a basic measuring method to investigate AFO device parts thermal stability. Thermal analysis (TG/DTG and DSC) was carried out before 3D printing is to characterize the thermal stability of each material. Keywords: Additive Manufacturing,Ankle Foot Orthosis (AFO),FusedDeposition Modelling,ThermalAnalysis, Refference: I. J. Pritchett, “Foot drop: Background, Anatomy, Pathophysiology,” Medscape Drugs, Dis. Proced., vol. 350, no. apr27_6, p. h1736, 2014. II. J. Graham, “Foot drop: Explaining the causes, characteristics and treatment,” Br. J. Neurosci. Nurs., vol. 6, no. 4, pp. 168–172, 2010. III. Y. Feng and Y. Song, “The Categories of AFO and Its Effect on Patients With Foot Impair: A Systemic Review,” Phys. Act. Heal., vol. 1, no. 1, pp. 8–16, 2017. IV. J. H. P. Pallari, K. W. Dalgarno, J. Munguia, L. Muraru, L. Peeraer, S. Telfer, and J. Woodburn” Design and additive fabrication of foot and ankle-foot orthoses”21st Annual International Solid Freeform Fabrication Symposium – An Additive Manufacturing Conference, SFF 2010 (2010) 834-845 V. Y. Jin, Y. He, and A. Shih, “Process Planning for the Fuse Deposition Modeling of Ankle-Foot-Othoses,” Procedia CIRP, vol. 42, no. Isem Xviii, pp. 760–765, 2016. VI. R. K. Chen, Y. an Jin, J. Wensman, and A. Shih, “Additive manufacturing of custom orthoses and prostheses-A review,” Addit. Manuf., vol. 12, pp. 77–89, 2016. VII. A. D. Maso and F. Cosmi, “ScienceDirect 3D-printed ankle-foot orthosis : a design method,” Mater. Today Proc., vol. 12, pp. 252–261, 2019. VIII. B. Yuan et al., “Designing of a passive knee-assisting exoskeleton for weight-bearing,” in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2017, vol. 10463 LNAI, pp. 273–285. IX. R. Spina, B. Cavalcante, and F. Lavecchia, “Diment LE, Thompson MS, Bergmann JHM. Clinical efficacy and effectiveness of 3D printing: a systematic review.,” AIP Conf. Proc., vol. 1960, 2018. X. M. Srivastava, S. Maheshwari, T. K. Kundra, and S. Rathee, “ScienceDirect Multi-Response Optimization of Fused Deposition Modelling Process Parameters of ABS Using Response Surface Methodology ( RSM ) -Based Desirability Analysis,” Mater. Today Proc., vol. 4, no. 2, pp. 1972–1977, 2017. XI. E. Malekipour, S. Attoye, and H. El-Mounayri, “Investigation of Layer Based Thermal Behavior in Fused Deposition Modeling Process by Infrared Thermography,” Procedia Manuf., vol. 26, pp. 1014–1022, 2018. XII. A. Patar, N. Jamlus, K. Makhtar, J. Mahmud, and T. Komeda, “Development of dynamic ankle foot orthosis for therapeutic application,” Procedia Eng., vol. 41, no. Iris, pp. 1432–1440, 2012. XIII. Y. A. Jin, H. Li, Y. He, and J. Z. Fu, “Quantitative analysis of surface profile in fused deposition modelling,” Addit. Manuf., vol. 8, pp. 142–148, 2015. XIV. M. Walbran, K. Turner, and A. J. McDaid, “Customized 3D printed ankle-foot orthosis with adaptable carbon fibre composite spring joint,” Cogent Eng., vol. 3, no. 1, pp. 1–11, 2016. XV. N. Wierzbicka, F. Górski, R. Wichniarek, and W. Kuczko, “The effect of process parameters in fused deposition modelling on bonding degree and mechanical properties,” Adv. Sci. Technol. Res. J., vol. 11, no. 3, pp. 283–288, 2017. XVI. S. Farah, D. G. Anderson, and R. Langer, “Physical and mechanical properties of PLA, and their functions in widespread applications — A comprehensive review,” Adv. Drug Deliv. Rev., vol. 107, pp. 367–392, 2016. XVII. S. Wojtyła, P. Klama, and T. Baran, “Is 3D printing safe ? Analysis of the thermal treatment of thermoplastics : ABS , PLA , PET , and,” vol. 9624, no. April, 2017. XVIII. G. Cicala et al., “Polylactide / lignin blends,” J. Therm. Anal. Calorim., 2017. XIX. S. Y. Lee, I. A. Kang, G. H. Doh, H. G. Yoon, B. D. Park, and Q. Wu, “Thermal and mechanical properties of wood flour/talc-filled polylactic acid composites: Effect of filler content and coupling treatment,” J. Thermoplast. Compos. Mater., vol. 21, no. 3, pp. 209–223, 2008. XX. Y. Tao, H. Wang, Z. Li, P. Li, and S. Q. Shi, “Development and application ofwood flour-filled polylactic acid composite filament for 3d printing,” Materials (Basel)., vol. 10, no. 4, pp. 1–6, 2017. XXI. D. Lewitus, S. McCarthy, A. Ophir, and S. Kenig, “The effect of nanoclays on the properties of PLLA-modified polymers Part 1: Mechanical and thermal properties,” J. Polym. Environ., vol. 14, no. 2, pp. 171–177, 2006. XXII. H. J. Chung, E. J. Lee, and S. T. Lim, “Comparison in glass transition and enthalpy relaxation between native and gelatinized rice starches,” Carbohydr. Polym., vol. 48, no. 3, pp. 287–298, 2002. View Download Journal Vol – 15 No -7, July 2020 CFD STUDIES OF MIXING BEHAVIOR OF INERT SAND WITH BIOMASS IN FLUIDIZED BED Authors: B.J.M.Rao,K.V.N.S.Rao, DOI NO: https://doi.org/10.26782/jmcms.2020.07.00053 admin July 26, 2020 Abstract: Agriculture deposits, which remains unused and often causes ecological problems, could play an important role as an energy source to meet energy needs in developing countries ‘ rural areas. Moreover, energy levels in these deposits are low and need to be elevated by introducing efficient operative conversion technologies to utilize these residues as fuels. In this context, the utilization of a fluidized bed innovation enables a wide range of non-uniform-sized low-grade fuels to be effectively converted into other forms of energy.This study was undertaken to evaluate the effectiveness of fluidized conversion method for transformation of agricultural by-products such as rice husk, sawdust, and groundnut shells into useful energy. The present investigation was conducted to know the mixing characteristics of sand and fuel have been found by conducting experiments with mixing ratio of rice husk (1:13), saw dust(1:5) and groundnut shells (1:12), the variation of particle movement in the bed and mixing characteristics are analyzed. The impact of sand molecule size on the fluidization speed of two biofuel and sand components is studied and recommended for groundnut shells using a sand molecule of 0.6 mm size and for rice husk, sawdust 0.4 mm sand particle size. Also, establish that the particle size of sand has a significant effect on mingling features in case of sawdust. In the next part of the investigation, the CFD simulations of the fluidized bed are done to investigate the mixing behavior of sand and biomass particles. A set of simulations are conducted by ANSYS FLUENT16; the state of the bed is the same as that of the test. The findings were presented with the volume fraction of sand and biomass particles in the form of contour plots. Keywords: Biomass,sand,mixing behavior,Volume Fraction,CFD model, Refference: I Anil Tekale, Swapna God, Balaji Bedre, Pankaj Vaghela, Ganesh Madake, Suvarna Labade (2017), Energy Production from Biomass: Review, International Journal of Innovative Science and Research Technology, Volume 2, Issue 10, ISSN No: – 2456 – 2165. II Anil Kumar, Nitin Kumar , Prashant Baredar , Ashish Shukla (2015), A review on biomass energy resources, potential, conversion and policy in India, Renewable and Sustainable Energy, Reviews 45-530-539. III Zhenglan Li, ZhenhuaXue (2015), Review of Biomass Energy utilization technology, 3rd International Conference on Material, Mechanical and Manufacturing Engineering. IV Abdeen Mustafa Omer (2011), Biomass energy resources utilisation and waste management, Journal of Agricultural Biotechnology and Sustainable Development Vol. 3(8), pp. 149 -170 V Rijul Dhingra, Abhinav Jain, Abhishek Pandey, and Srishti Mahajan (2014), Assessment of Renewable Energy in India, International Journal of Environmental Science and Development, Vol. 5, No. 5. VI Paulina Drożyner, Wojciech Rejmer, Piotr Starowicz,AndrzejKlasa, Krystyna A. Skibniewska (2013), Biomass as a Renewable Source of Energy, Technical Sciences 16(3), 211–220. VII Souvik Das, Swati Sikdar (2016), A Review on the Non-conventional Energy Sources in Indian Perspective, International Research Journal of Engineering and Technology (IRJET), Volume: 03 Issue: 02. VIII Maninder, Rupinderjit Singh Kathuria, Sonia Grover, Using Agricultural Residues as a Biomass Briquetting: An Alternative Source of Energy, IOSR Journal of Electrical and Electronics Engineering (IOSRJEEE), ISSN: 2278-1676 Volume 1, Issue 5 (July-Aug. 2012), PP 11-15. IX H.B.Goyal, DiptenduldDeal, R.C.Saxena (2006) Bio-fuels from thermochemical conversion of renewable resources: A review, Renewable and Sustainable Energy Reviews, Volume 12, Issue 2Pages 504-517. X Digambar H. Patil, J. K. Shinde(2017) A Review Paper on Study of Bubbling Fluidized Bed Gasifier, International Journal for Innovative Research in Science & Technology, Volume 4, Issue 4 XI Neil T.M. Duffy, John A. Eaton (2013) Investigation of factors affecting channelling in fixed-bed solid fuel combustion using CFD, Combustion and Flame 160, 2204–2220. XII Xing Wu, Kai Li, Feiyue and Xifeng Zhu (2017), Fluidization Behavior of Biomass Particles and its Improvement in a Cold Visualized Fluidized, Bio Resources 12(2), 3546-3559. XIII N.G. Deen, M. Van Sint Annaland, M.A. Van der Hoef, J.A.M. Kuipers (2007), Reviewof discrete particle modeling of fluidized beds, Chemical Engineering Science 62, 28 – 44. XIV BaskaraSethupathySubbaiah, Deepak Kumar Murugan, Dinesh Babu Deenadayalan, Dhamodharan.M.I (2014), Gasification of Biomass Using Fluidized Bed, International Journal of Innovative Research in Science, Engineering and Technology, Vol. 3, Issue 2. XV Priyanka Kaushal, Tobias Pröll and Hermann Hofbauer, Modelling and simulation of the biomass fired dual fluidized bed gasifier at Guessing/Austria. XVI Dawit DiribaGuta (2012), Assessment of Biomass Fuel Resource Potential and Utilization in Ethiopia: Sourcing Strategies for Renewable Energies, International Journal of Renewable Energy Research, Vol.2, and No.1. View Download Journal Vol – 15 No -7, July 2020 AN APPROACH FOR OPTIMISING THE FLOW RATE CONDITIONS OF A DIVERGENT NOZZLE UNDER DIFFERENT ANGULAR CONDITIONS Authors: Lam Ratna Raju ,Ch. Pavan Satyanarayana,Neelamsetty Vijaya Kavya, DOI NO: https://doi.org/10.26782/jmcms.2020.07.00054 admin July 26, 2020 Abstract: A spout is a device which is used to offer the guidance to the gases leaving the burning chamber. Spout is a chamber which has a capability to change over the thermo-compound essentials created within the ignition chamber into lively vitality. The spout adjustments over the low speed, excessive weight, excessive temperature fuel in the consuming chamber into rapid gasoline of decrease weight and low temperature. An exciting spout is used if the spout weight volume is superior vehicles in supersonic airplane machines commonly combine a few sort of a distinctive spout. Our exam is surpassed on the use of programming like Ansys Workbench for arranging of the spout and Fluent 15.0 for separating the streams inside the spout. The events of staggers for the pipe formed spouts have been seen close by trade parameters for numerous considered one of a kind edges. The parameters underneath recognition are differentiated and that of shape spout for singular terrific edges by using keeping up the gulf, outlet and throat width and lengths of joined together and diverse quantities as same. The simultaneous component and throat expansiveness are kept regular over the cases.The surprise of stun became envisioned and the effects exhibited near closeness in direction of motion of Mach circle and its appearance plans as exposed in numerous preliminary considers on advancement in pipe molded particular spouts with assorted edges four°,7°, 10°, Occurrence of stun is seen with higher special factors Keywords: Nozzle,Supersonic Rocket Engine,Divergent edges, Refference: I. Varun, R.; Sundararajan,T.; Usha,R.; Srinivasan,ok.; Interaction among particle-laden under increased twin supersonic jets, Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering 2010 224: 1005. II. Pandey,K.M.; Singh, A.P.; CFD Analysis of Conical Nozzle for Mach 3 at Various Angles of Divergence with Fluent Software, International Journal of Chemical Engineering and Applications, Vol. 1, No. 2, August 2010, ISSN: 2010-0221. III. Natta, Pardhasaradhi.; Kumar, V.Ranjith.; Rao, Dr. Y.V. Hanumantha.; Flow Analysis of Rocket Nozzle Using Computational Fluid Dynamics (Cfd), International Journal of Engineering Research and Applications (IJERA), ISSN: 2248-9622,Vol. 2, Issue five, September- October 2012, pp.1226-1235. IV. K.M. Pandey, Member IACSIT and A.P. Singh. K.M.Pandey, Member, IACSIT and S.K.YadavK.M.Pandey and S.K.Yadav, ―CFD Analysis of a Rocket Nozzle with Two Inlets at Mach2.1, Journal of Environmental Research and Development, Vol 5, No 2, 2010, pp- 308-321. V. Shigeru Aso, ArifNur Hakim, Shingo Miyamoto, Kei Inoue and Yasuhiro Tani “ Fundamental examine of supersonic combustion in natural air waft with use of surprise tunnel” Department of Aeronautics and Astronautics, Kyushu University, Japan , Acta Astronautica 57 (2005) 384 – 389. VI. P. Padmanathan, Dr. S. Vaidyanathan, Computational Analysis of Shockwave in Convergent Divergent Nozzle, International Journal of Engineering Research and Applications (IJERA), ISSN: 2248-9622 , Vol. 2, Issue 2,Mar-Apr 2012, pp.1597-1605. VII. Adamson, T.C., Jr., and Nicholls., J.A., “On the shape of jets from Highly below improved Nozzles into Still Air,” Journal of the Aerospace Sciences, Vol.26, No.1, Jan 1959, pp. Sixteen-24. VIII. Lewis, C. H., Jr., and Carlson, D. J., “Normal Shock Location in underneath increased Gas and Gas particle Jets,” AIAA Journal, Vol 2, No.4, April 1964, pp. 776-777. Books IX. Anderson, John D.Jr.; Modern Compressible Flow with Historical Perspective, Third edition, 2012 X. Versteeg. H.; Malalasekra.W.; An Introduction to Computational Fluid Dynamics The Finite Volume Method, Second Edition,2009. XI. H.K.Versteeg and W.Malala Sekhara, “An introduction to Computational fluid Dynamics”, British Library cataloguing pub, 4th version, 1996. XII. Lars Davidson, “An introduction to turbulenceModels”, Department of thermo and fluid dynamics, Chalmers college of era, Goteborg, Sweden, November, 2003. XIII. Karna s. Patel, “CFD analysis of an aerofoil”, International Journal of engineering studies,2009. XIV. K.M. Pandey, Member IACSIT and A.P. Singh “CFD Analysis of Conical Nozzle for Mach 3 at Various Angles of Divergence with Fluent Software,2017. XV. P. Parthiban, M. Robert Sagayadoss, T. Ambikapathi, Design And Analysis Of Rocket Engine Nozzle by way of the usage of CFD and Optimization of Nozzle parameters, International Journal of Engineering Research, Vol.Three., Issue.5., 2015 (Sept.-Oct.). View Download Journal Vol – 15 No -7, July 2020 DESIGN OPTIMIZATION OF DRIVE SHAFT FOR AN AUTOMOBILE APPLICATIONS Authors: Govindarajulu Eedara,P. N. Manthru Naik, DOI NO: https://doi.org/10.26782/jmcms.2020.07.00055 admin July 26, 2020 Abstract: The driveshaft is a mechanical instrument that is used in automobiles. The other name of the drive shaft is driveshaft is prop shaft. It has one long cylindrical structure consist of two universal joints. By using the driveshaft it transfers the rotary motion to the differential by using the helical gearbox. By using this rotary motion the rare wheels will run. The 3dimensional Model of automobile drive Shaft is designed using CATIA parametric which enables product development processes and thereby brings about an optimum design. Now a day’s steel is using the best material for the driveshaft.In this paper replacing the composite materials (Kevlar, e-glass epoxy) instead of steel material and itreduces a considerable amount of weight when compared to the conventional steel shaft. The composite driveshaft have high modulus is designed by using CATIA software and tested in ANSYS for optimization of design or material check and providing the best datebook Keywords: The driveshaft ,CATIA,automobile,steel,composite materials,ANSYS,Kevla,e-glass epoxy, Refference: I A.R. Abu Talib, Aidy Ali, Mohamed A. Badie, Nur Azienda Che Lah, A.F. Golestaneh Developing a hybrid, carbon/glass-fiber-reinforced, epoxy composite automotive driveshaft, Material and Design, volume31, 2010, pp 514 – 521 II ErcanSevkat, Hikmet Tumer, Residual torsional properties of composite shafts subjected to impact Loadings, Materials, and design, volume – 51, 2013, pp -956-967. III H. Bayrakceken, S. Tasgetiren, I. Yavuz two cases of failure in the power transmission system on vehicles: A Universal joint yoke and a drive shaft, volume-14,2007,pp71. IV H.B.H. Gubran, Dynamics of hybrid shafts, Mechanics Research communication, volume – 32, 2005, pp – 368-374. V Shaw D, Simitses DJ, SheinmanI. Imperfection sensitivity of laminated cylindrical shells in torsion and axial compression. ComposStruct 1985; 4(3) pp:35–60. View Download Journal Vol – 15 No -7, July 2020 EXPERIMENTAL EVALUATION OF AN SI ENGINE USING E10 EQUIVALENT TERNARY GASOLINE- ALCOHOL BLENDS". JOURNAL OF MECHANICS OF CONTINUA AND MATHEMATICAL SCIENCES 15, n.º 7 (26 de julio de 2020). http://dx.doi.org/10.26782/jmcms.2020.07.00056.

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Tesis sobre el tema "WF.143"

Chauveau, Amandine. "La toux en dehors d'une infection chez l'enfant : trajectoires au cours des dix premières années de vie, association avec les maladies allergiques et rôle de l'environnement périnatal". Electronic Thesis or Diss., Bourgogne Franche-Comté, 2023. http://indexation.univ-fcomte.fr/nuxeo/site/esupversions/c5effcd3-ffa9-426d-88b6-ddd6d823c850.

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La toux est un symptôme respiratoire fréquent et non spécifique chez l’enfant, habituellement présent uniquement durant une infection aigue des voies respiratoires. Cependant, certains enfants présentent une toux par excès de sensibilité se manifestant par des épisodes de toux fréquents ou récurrents, en dehors d’une infection, et des facteurs déclenchants habituellement non tussigènes. Bien qu’un des mécanismes étiologiques de cette hypersensibilité soit l’atopie, très peu d’études se sont intéressées à la relation entre trajectoires de toux dans l’enfance et maladies allergiques ainsi qu’à leur association avec l’environnement précoce.Afin d’identifier les trajectoires de toux dans l’enfance, d’analyser leur relation avec les maladies allergiques et avec l’environnement précoce, le travail de cette thèse a porté sur deux volets complémentaires : un volet épidémiologique observationnel chez l’enfant et un volet expérimental chez le lapin. Le volet épidémiologique reposait sur l’analyse des données de la cohorte prospective européenne PASTURE (Protection against Allergy: STUdy in Rural Environment). Parmi les 961 enfants inclus dans l’étude épidémiologique, une analyse en classes latentes a permis d’identifier cinq trajectoires de toux en dehors d’une infection : peu ou pas de symptômes (59,9 %), transitoire aigue (24,1 %), transitoire modérée (6,8 %), persistante à début tardif (4,8 %), et persistante à début précoce (4,4 %). En comparaison avec la trajectoire peu ou pas de symptômes, les autres trajectoires étaient significativement associées avec les sibilants, l’asthme et la rhinite allergique. La trajectoire persistante à début précoce avait la plus forte association pour l’asthme et était inversement associée à l’environnement fermier. L’allergie alimentaire était associée aux deux trajectoires persistantes. La sensibilisation atopique était associée uniquement à la toux persistante à début tardif. La consommation de lait de ferme bouilli durant la première année de vie était la seule exposition spécifique à l’environnement fermier significativement associée à une diminution du risque de toux persistante à début précoce et de toux transitoire aigue. Des infections respiratoires répétées ou prolongées dans la première année de vie étaient significativement associées à un risque plus élevé de toux persistante à début précoce. Le volet expérimental a permis d’évaluer l’impact de l’exposition périnatale à la poussière de ferme sur la sensibilité tussigène et la réactivité bronchique chez un modèle de lapin d’inflammation bronchique d’origine allergique. Un environnement spécifique a été appliqué aux lapines gestantes et à leurs lapereaux jusqu’à la sixième semaine de vie (zone exempte d’agent pathogène pour le groupe contrôle ; étable de veaux pour le groupe ferme). Les lapereaux étaient ensuite hébergés dans une zone conventionnelle de l’animalerie et sensibilisés à l’ovalbumine par voie intrapéritonéale. La sensibilité à la toux a été évaluée par la stimulation mécanique de la toux et la réactivité bronchique par un test à la méthacholine. Nous n’avons pas retrouvé d’effet de l’exposition précoce à une étable de veaux sur la sensibilité tussigène ni la réactivité bronchique.Nos résultats suggèrent un lien étroit entre toux persistante et pathologies atopiques ainsi que l’existence de potentiels facteurs de prévention communs. Les enfants présentant une toux persistante ou récurrente devraient être orientés vers un médecin allergologue pour qu’une évaluation allergologique complète soit réalisée. Les études de prévention des pathologies atopiques devraient également s’intéresser aux symptômes de toux en dehors d’une infection afin d’évaluer la pertinence de développer des stratégies de prévention communes
Cough is a frequent and non-specific respiratory symptom in children. In the majority of otherwise healthy children, cough is a symptom related to a self-limiting viral upper respiratory tract infection. However, some children have cough hypersensitivy that manifests as frequent or recurrent coughs, without a respiratory infection, and triggered by normally innocuous stimuli. Although atopy is one of the etiological mechanisms of this hypersensitivity, few studies has explored the relationship between cough trajectories in children and allergic diseases, as well as their association with early environment.In order to identify trajectories of cough in childhood, to analyse their relationship with allergic diseases and with early environment, the thesis work consisted of two complementary parts: an epidemiological observational part in children and an experimental part in rabbit. The epidemiological part was based on analysis of data from the prospective European birth cohort PASTURE (Protection against Allergy: STUdy in Rural Environment). Among the 961 children included in the epidemiological study, a latent class analysis allowed to identify five trajectories of cough without a cold: never of infrequent (59.9%), acute transient (24.1%), moderate transient (6.8%), late persistent (4.8%) and early persistent (4.4%). Compared with the never/infrequent trajectory, the other trajectories were significantly associated with wheezing, asthma and allergic rhinitis. Early persistent trajectory had the strongest association with asthma and was inversely associated with farm environment. Food allergy was associated with both persistent trajectories. Atopic sensitisation was only associated with the late persistent trajectory. Consumption of boiled farm milk during the first year of life was the only farm-specific exposure significantly associated with a decreased risk of early persistent cough and acute transient cough. Repeated or prolonged respiratory tract infections during the first year of life was associated with a higher risk of early persistent cough. The experimental part allowed to evaluate the impact of perinatal exposure to farm dust on cough sensitivity and airway responsiveness in an allergic airway inflammation rabbit model. A specific environment has been applied to pregnant rabbits and their offspring until six weeks after birth (pathogen-free zone for the control group, calf barn for the farm group). Rabbit pups were then housed in a conventional zone and sensitised to ovalbumin by intraperitoneal route. Cough sensitivity was assessed by mechanical stimulation of cough and airway responsiveness by a methacholine challenge. We did not find any effect of early exposure to the calf barn on cough sensitivity or bronchial reactivity.Our results suggest 1/ a close link between persistent cough and atopic diseases and 2/ the existence of potential common preventive factors. Children having persistent or recurrent cough should be referred to an allergist for a complete allergy assessment. Prevention studies for atopic diseases should also explored symptoms of cough without a cold in order to evaluate the relevance of developing common prevention strategies

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