Bibliografías temáticas / WBH

Literatura académica sobre el tema "WBH"

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Publicado: 25 de julio de 2024

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Artículos de revistas sobre el tema "WBH"

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Robins, H. I., D. Rushing, M. Kutz, K. D. Tutsch, C. L. Tiggelaar, D. Paul, D. Spriggs et al. "Phase I clinical trial of melphalan and 41.8 degrees C whole-body hyperthermia in cancer patients." Journal of Clinical Oncology 15, n.º 1 (enero de 1997): 158–64. http://dx.doi.org/10.1200/jco.1997.15.1.158.

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PURPOSE To evaluate the biologic interactions and toxicities of melphalan (L-PAM) combined with 41.8 degrees C whole-body hyperthermia (WBH) for 60 minutes. PATIENTS AND METHODS Sixteen patients with refractory cancer were treated (May 1992 to May 1995) with WBH alone during week 1) thereafter patients were randomized to receive either L-PAM alone on week 2 and L-PAM plus WBH on week 5, or the reverse sequence. Patients who demonstrated clinical improvement received WBH plus L-PAM monthly. Dose levels of L-PAM were 10 mg/m2 (n = 3), 15 mg/m2 (n = 3), 17.5 mg/m2 (n = 6), and 20 mg/m2 (n = 4). L-PAM was administered at target temperature; WBH was administered with an Aquatherm radiant-heat device (patent pending; Cancer Research Institute, New York, NY). RESULTS Comparisons of mean WBC count and platelet nadirs for L-PAM alone and L-PAM plus WBH demonstrated that the addition of WBH resulted in nadir counts that were, on average, 25% lower. There were no instances of febrile neutropenia or bleeding. Toxicities allowed for escalation of L-PAM to 20 mg/m2; all four patients at this level experienced grade 4 myelosuppression. No significant myelosuppression was observed at 10 and 15 mg/m2. Grade 3 myelosuppression was observed in two of six patients at 17.5 mg/m2. Responses included complete remission (CR) of pancreatic cancer (10 mg/m2), partial remission (PR) of malignant melanoma in two patients (20 mg/m2), and transient clinical and/or serologic improvement in five patients. The pharmacokinetics of L-PAM were not altered by WBH. Observed cytokine induction by WBH is also discussed in detail. CONCLUSION We conclude that L-PAM with 41.8 degrees C WBH is well tolerated. Clinical results are consistent with preclinical predictions and provide a foundation for second-generation trials now in progress.
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Robins, H. I., J. D. Cohen, C. L. Schmitt, K. D. Tutsch, C. Feierabend, R. Z. Arzoomanian, D. Alberti, F. d'Oleire, W. Longo y C. Heiss. "Phase I clinical trial of carboplatin and 41.8 degrees C whole-body hyperthermia in cancer patients." Journal of Clinical Oncology 11, n.º 9 (septiembre de 1993): 1787–94. http://dx.doi.org/10.1200/jco.1993.11.9.1787.

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PURPOSE To evaluate the biologic interactions and toxicities of carboplatin combined with 41.8 degrees C whole-body hyperthermia (WBH) for 60 minutes in a phase I clinical trial. PATIENTS AND METHODS Thirty assessable patients with cancer refractory to conventional therapy were treated. During induction therapy, patients received WBH alone in week 1, WBH plus carboplatin in week 2, and carboplatin alone in week 5. Carboplatin dose was escalated (three patients per group) as follows: 100, 150, 200, 250, 300, 350, 400, 480, and 575 mg/m2; three additional patients were entered at 480 mg/m2. Carboplatin was administered at target temperature. RESULTS Comparisons of the mean/median WBC and platelet nadirs for carboplatin alone and carboplatin plus WBH demonstrated no enhancing effect by WBH. Toxicities including nausea and/or vomiting, as well as myelosuppression, were within acceptable limits, allowing for escalation to a dose of 575 mg/m2; three of three patients at this dose level experienced grade 4 myelosuppression with no associated infection or bleeding. No renal toxicity was observed. Analysis of platinum in plasma ultrafiltrate and urine showed only slight effects of WBH on the pharmacokinetics and renal excretion of platinum. Responses included the following: lung--minor response (200 mg/m2); gastrointestinal neuroendocrine--complete response (CR) (400 mg/m2); pancreatic--partial response (PR) (480 mg/m2); small bowel--PR (575 mg/m2); ovarian--CR, two patients (575 mg/m2), with marker data suggesting WBH enhancement of carboplatin cytotoxicity. Another three patients experienced clinical improvement after WBH plus carboplatin, but progression with carboplatin alone (lung, 400 mg/m2; gastrointestinal neuroendocrine, 480 mg/m2; melanoma, 480 mg/m2). CONCLUSION We conclude that carboplatin with WBH is well tolerated even at conventional carboplatin doses. Clinical results are consistent with preclinical predictions of an increased therapeutic index for this combination, which encourages future clinical studies.
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Borloo, Noor, Anne Smits, Liesbeth Thewissen, Pieter Annaert y Karel Allegaert. "Creatinine Trends and Patterns in Neonates Undergoing Whole Body Hypothermia: A Systematic Review". Children 8, n.º 6 (4 de junio de 2021): 475. http://dx.doi.org/10.3390/children8060475.

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Many neonates undergoing whole body hypothermia (WBH) following moderate to severe perinatal asphyxia may also suffer from renal impairment. While recent data suggest WBH-related reno-protection, differences in serum creatinine (Scr) patterns to reference patterns were not yet reported. We therefore aimed to document Scr trends and patterns in asphyxiated neonates undergoing WBH and compared these to centiles from a reference Scr data set of non-asphyxiated (near)term neonates. Using a systematic review strategy, reports on Scr trends (mean ± SD, median or interquartile range) were collected (day 1–7) in WBH cohorts and compared to centiles of an earlier reported reference cohort of non-asphyxia cases. Based on 13 papers on asphyxia + WBH cases, a pattern of postnatal Scr trends in asphyxia + WBH cases was constructed. Compared to the reference 50th centile Scr values, mean or median Scr values at birth and up to 48 h were higher in asphyxia + WBH cases with a subsequent uncertain declining trend towards, at best, high or high–normal creatinine values afterwards. Such patterns are valuable for anticipating average changes in renal drug clearance but do not yet cover the relevant inter-patient variability observed in WBH cases, as this needs pooling of individual Screa profiles, preferably beyond the first week of life.
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Krnjajic, Davor, Dustin R. Allen, Cory L. Butts y David M. Keller. "Carotid baroreflex control of heart rate is enhanced, while control of mean arterial pressure is preserved during whole body heat stress in young healthy men". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 311, n.º 4 (1 de octubre de 2016): R735—R741. http://dx.doi.org/10.1152/ajpregu.00152.2016.

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Whole body heat stress (WBH) results in numerous cardiovascular alterations that ultimately reduce orthostatic tolerance. While impaired carotid baroreflex (CBR) function during WBH has been reported as a potential reason for this decrement, study design considerations may limit interpretation of previous findings. We sought to test the hypothesis that CBR function is unaltered during WBH. CBR function was assessed in 10 healthy male subjects (age: 26 ± 3; height: 185 ± 7 cm; weight: 82 ± 10 kg; BMI: 24 ± 3 kg/m2; means ± SD) using 5-s trials of neck pressure (+45, +30, and +15 Torr) and neck suction (−20, −40, −60, and −80 Torr) during normothermia (NT) and passive WBH (Δ core temp ∼1°C). Analyses of stimulus response curves (four-parameter logistic model) for CBR control of heart rate (CBR-HR) and mean arterial pressure (CBR-MAP), as well as separate two-way ANOVA of the hypotensive and hypertensive stimuli (factor 1: thermal condition, factor 2: chamber pressure), were performed. For CBR-HR, maximal gain was increased during WBH (−0.73 ± 0.11) compared with NT (−0.39 ± 0.04, mean ± SE, P = 0.03). In addition, the CBR-HR responding range was increased during WBH (33 ± 5) compared with NT (19 ± 2 bpm, P = 0.03). Separate analysis of hypertensive stimulation revealed enhanced HR responses during WBH at −40, −60, and −80 Torr (condition × chamber pressure interaction, P = 0.049) compared with NT. For CBR-MAP, both logistic analysis and separate two-way ANOVA revealed no differences during WBH. Therefore, in response to passive WBH, CBR control of heart rate (enhanced) and arterial pressure (no change) is well preserved.
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Sheppard, Stephanie Rosenbloom, Sameer Desale y Kabir Abubakar. "Respiratory and Hemodynamic Changes in Neonates with Hypoxic–Ischemic Encephalopathy during and after Whole-Body Hypothermia". American Journal of Perinatology 38, n.º 01 (14 de agosto de 2019): 037–43. http://dx.doi.org/10.1055/s-0039-1694730.

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Abstract Objective This study aimed to determine the degree to which whole-body hypothermia (WBH) impacts hemodynamic and respiratory status during hypothermia and the subsequent rewarming period in neonates with hypoxic–ischemic encephalopathy (HIE). Study Design This is a retrospective study reviewing the medical records of infants treated with WBH. Data including oxygenation index (OI), ventilator efficiency index (VEI), fraction of inspired oxygen (FiO2), blood lactate level, heart rate (HR), and mean blood pressure (MBP) were collected from defined time points from the beginning, middle, and end of WBH and then every 2 hours from the beginning of rewarming for 14 hours thereafter. The analysis included 65 infants. Data were analyzed using a piecewise linear regression with a mixed-effect model. Results HR decreased during WBH and significantly increased during rewarming. Lactate level, OI, VEI, FiO2, and MBP all decreased during WBH but showed no significant change during and after rewarming. Conclusion There was a decrease in metabolic demand as measured by oxygen requirement, OI, HR, and MBP during WBH, but only HR increased during rewarming, with no significant change in the other parameters. Some of this effect may be explained by improvement in the respiratory condition over time.
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Liu, Rui, Min Wang y Jin-Ao Duan. "Antipyretic and Antioxidant Activities of the Aqueous Extract of Cornu Bubali (Water Buffalo Horn)". American Journal of Chinese Medicine 38, n.º 02 (enero de 2010): 293–306. http://dx.doi.org/10.1142/s0192415x10007853.

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Cornu Bubali (water buffalo horn, WBH) is an animal-derived product which is widely used in Traditional Chinese Medicine (TCM) for dispelling heat, relieving convulsions and cooling blood. The purpose of this study was to investigate the antipyretic activity of WBH aqueous extract and its potential mechanism. Two hyperthermia models, yeast-induced (infectious) and skimmed milk-induced (noninfectious) hyperthermia were employed to evaluate the antipyretic effect and the results showed that rectal temperature of hyperthermia animals was decreased significantly after oral administration of WBH extract. The production of tumor necrosis factor-α (TNF-α)-induced prostaglandin E2 (PGE2) in rat cerebral microvascular endothelial cells (rCMECs) was inhibited by WBH extract in the concentrations of 10 μg/ml and 100 μg/ml. The WBH extract protected rCMECs survival from hydrogen peroxide ( H2O2 )-induced toxicity and inhibited the H2O2 -induced leakage of lactate dehydrogenase (LDH) enzyme release at a dose ranging from 5 μg/ml to 100 μg/ml. It could also increase the superoxide dismutase (SOD) and catalase (CAT) enzyme activities. The results suggest that Cornu Bubali exhibits antipyretic activity on both infectious and noninfectious hyperthermia. The antipyretic activity of WBH may be due to the effects on enhancing antioxidation enzyme activities, decreasing PGE2 production, and protecting the rCMECs against H2O2 -induced injury.
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Cui, Jian, Zhaohui Gao, Cheryl Blaha, Jonathan Carter Luck, Kristen Brandt y Lawrence I. Sinoway. "Moderate whole body heating attenuates the exercise pressor reflex responses in older humans". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 320, n.º 5 (1 de mayo de 2021): R757—R769. http://dx.doi.org/10.1152/ajpregu.00232.2020.

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Prior reports show that whole body heat stress attenuates the pressor response to exercise in young healthy subjects. The effects of moderate whole body heating (WBH; e.g., increase in internal temperature Tcore of ∼0.4°C–0.5°C) or limb heating on sympathetic and cardiovascular responses to exercise in older healthy humans remain unclear. We examined the muscle sympathetic nerve activity (MSNA), mean arterial blood pressure (MAP), and heart rate (HR) in 14 older (62 ± 2 yr) healthy subjects during fatiguing isometric handgrip exercise and postexercise circulatory occlusion (PECO). The protocol was performed under normothermic, moderate WBH, and local limb (i.e., forearm) heating conditions during three visits. During the mild WBH stage (increase in Tcore of <0.3°C), HR increased, whereas BP and MSNA decreased from baseline. Under the moderate WBH condition (increase in Tcore of ∼0.4°C), BP decreased, HR increased, and MSNA was unchanged from baseline. Compared with the normothermic trial, the absolute MAP during fatiguing exercise and PECO was lower during the WBH trial. Moreover, MSNA and MAP responses (i.e., changes) to fatiguing exercise were also less than those seen during the normothermic trial. Limb heating induced a similar increase in forearm muscle temperature to that seen in the WBH trial (∼0.7°C–1.5°C). Limb heating did not alter resting MAP, HR, or MSNA. The MSNA and hemodynamic responses to exercise in the limb heating trial were not different from those in the normothermic trial. These data suggest that moderate WBH attenuates MSNA and BP responses to exercise in older healthy humans.
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Dominic J, Sturm, Kunz Christoph, Peteinatos Gerassimos y Gerhards Roland. "Do cover crop sowing date and fertilization affect field weed suppression?" Plant, Soil and Environment 63, No. 2 (7 de marzo de 2017): 82–88. http://dx.doi.org/10.17221/1/2017-pse.

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The weed suppressive ability of oilseed radish (Raphanus sativus var. oleiformis Pers.) cover crop is attributed to high competitiveness for resources and biochemical effects on weeds. The oilseed radish cover crop was sown in five treatments plus an untreated control over a period of five weeks before and three weeks after winter wheat harvest. Additionally, fertilization effects on oilseed radish biomass and weed suppression were measured. The highest biomass of the cover crop was observed 12 weeks after harvest (WAH) when the oilseed radish was sown one week after harvest (1 WAH) (2015) and five weeks before harvest (5 WBH) (2016). No differences of fertilization were observed concerning oilseed radish and weed biomass in 2015, whereby increased biomass was found after fertilization in 2016. The highest weed control efficacy of up to 83% and 90% was achieved in treatments 1 WAH (2015) and 5 WBH (2016) at 12 WAH. The early sowing of oilseed radish in winter wheat resulted in low germination and biomass yield within the field, due to low precipitation in 2015. Nevertheless, there is a high potential of early sown oilseed radish for higher weed control efficacy, which was demonstrated in 2016.
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Khanlarian, Cynthia J. y Rahul Singh. "An Exploratory Study of the Online Learning Environment". Issues in Accounting Education 29, n.º 1 (1 de septiembre de 2013): 117–47. http://dx.doi.org/10.2308/iace-50614.

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ABSTRACT Web-based homework (WBH) is an increasingly important phenomenon. There is little research about its character, the nature of its impact on student performance, and how that impact evolves over an academic term. The primary research questions addressed in this study are: What relevant factors in a WBH learning environment impact students' performance? And how does the impact of these factors change over the course of an academic term? This paper examines and identifies significant factors in a WBH learning environment and how they impact student performance. We studied over 300 students using WBH extensively for their coursework, throughout a semester in an undergraduate class at a large public university. In this paper, we present factors in the WBH learning environment that were found to have a significant impact on student performance during the course of a semester. In addition to individual and technological factors, this study presents findings that demonstrate that frustration with IT use is a component of the learning environment, and as a construct, has a larger impact than usefulness on student performance at the end of a course. Our results indicate that educators may benefit from training students and engaging them in utility of co-operative learning assignments to mitigate the level of frustration with the software in the WBH learning environment and improve student performance.
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Langhorst, Jost, Anna K. Koch, Christina Kehm, Özlem Öznur, Harald Engler y Winfried Häuser. "Mild Water-Filtered Infrared-A Whole-Body Hyperthermia Reduces Pain in Patients with Fibromyalgia Syndrome—A Randomized Sham-Controlled Trial". Journal of Clinical Medicine 12, n.º 8 (18 de abril de 2023): 2945. http://dx.doi.org/10.3390/jcm12082945.

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The challenging treatment situation of patients with fibromyalgia syndrome (FMS) requires additional therapy options. The effects of water-filtered infrared-A whole-body hyperthermia (WBH) versus sham hyperthermia on pain intensity were investigated in an outpatient setting within a two-armed randomized sham-controlled trial. n = 41 participants aged between 18 and 70 years with a medically confirmed diagnosis of FMS were randomized to WBH (intervention; n = 21) or sham hyperthermia (control; n = 20). Six treatments with mild water-filtered infrared-A WBH over a period of three weeks with at least one day in between treatments were applied. On average, the maximum temperature was 38.7 °C for a duration of approximately 15 min. The control group received exactly the same treatment except that an insulating foil between the patient and the hyperthermia device blocked most of the radiation. Primary outcome was pain intensity measured by the Brief Pain Inventory at week 4. Secondary outcomes included blood cytokine levels and FMS-related core symptoms and quality of life. Pain intensity at week 4 was significantly different between the groups in favor of WBH (p = 0.015). A statistically significant pain reduction in favor of WBH was also found at week 30 (p = 0.002). Mild water-filtered infrared-A WBH effectively reduced pain intensity at the end of treatment and follow-up.
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Tesis sobre el tema "WBH"

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Schlicht, Juliana [Verfasser], Gerhard [Herausgeber] Minnameier y Birgit [Herausgeber] Ziegler. "Kommunikation und Kooperation in Geschäftsprozessen : Modellierung aus pädagogischer, ökonomischer und informationstechnischer Perspektive / Juliana Schlicht". Bielefeld : wbv Media, 2019. http://www.wbv.de/wbe.

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Imhof-Rudolph, Heike. "Wehrpflicht ade - tut Scheiden weh?" Universität Potsdam, 2010. http://opus.kobv.de/ubp/volltexte/2010/4897/.

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Wieviel Bundeswehr braucht Deutschland? Und wozu? Das primäre Ziel der Bundeswehr, die Landesverteidigung, ist ein genauso antiquierter Begriff wie ihre Struktur. Welche Transformation der Streitkräfte ist geboten?
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McGowan, Karen Elizabeth. "Percutaneous local anaesthesia wth amethocaine". Thesis, Queen's University Belfast, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296790.

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Castellano, Vincent, Albin Einarsson y Petter Norder. "Analys av pantograf WBL 88". Thesis, KTH, Maskinkonstruktion (Inst.), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-175782.

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På uppdrag av Järnvägsgruppen på KTH skulle interaktionen mellan kontaktledning och pantograf simuleras och analyseras. Detta för att kunna presentera ett förbättrat konstruktionsförslag på pantografen som skulle leda till en jämnare kontaktkraft vid höghastighetsdrift, 300 km/h. Den dynamiska simuleringen byggde på en befintlig pantograf, WBL 88, som tillverkas av Schunk och används i Sverige på höghastighetståget X2000. Kontaktledningen består av koppar som sprids i naturen när den nöts. Då kopparpartiklar är hälsofarligt har aluminium studerats och jämförts som en potentiell ersättare. Materialjämförelsen har behandlat nötningsvolym, konduktivitet, hållfasthet och miljöaspekter. För att kunna analysera interaktionen mellan kontaktledning och pantograf har den dynamiska simuleringen genomförts i MD Adams/View 2011 där pantografens parametrar varierats för att få en jämnare kontaktkraft. Materialjämförelsen grundar sig på beräkningar som kan relateras till materialens mekaniska egenskaper. Den dynamiska simuleringen gav en jämnare kontaktkraft genom att reducera kontaktskenans vikt samt öka dess fjäderstyvhet och dämpning. Dessa förändringar resulterade i att kontaktskenan lättare kunde följa kontaktledningen utan att tappa kontakten. Materialjämförelsen gav att koppar har för ändamålet och med befintlig utformning av kontaktledningen bättre mekaniska egenskaper än aluminium.
On behalf of the Railway Group at KTH the interaction between a pantograph and the overhead catenary wire was simulated and analyzed. The purpose of this was to present an improved design suggestion of the pantograph that would lead to a more even contact force at high speed operation, 300 km/h. The dynamic simulation was based on an existing pantograph, WBL 88, manufactured by Schunk and is currently used in Sweden on the highspeed train X2000. The catenary is made of copper which is spread in the environment due to wear. Since copper particles are harmful, aluminum has been studied and compared as an alternative material. The material comparison includes wear volume, conductivity, strength and environmental aspects. In order to analyze the interaction between the catenary and the pantograph, dynamic simulations were carried out in MD Adams/View 2011. During the simulations, the parameters of the pantograph have been varied to obtain an improved and more even contact force. The material comparison is based on calculations that can be related to the mechanical properties of the materials. The results of the dynamic simulation showed that by reducing the weight of the contact strip and increasing its spring stiffness and damping, the contact force became less varied and more even. The changes of the parameters lead to that the contact strip could more easily follow the catenary without losing contact. The material comparison showed that copper has better mechanical properties for the specific purpose than aluminum.
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Woolf, Kurtus Steven. "Pre-Eruptive Conditions of the Oligocene Wah Wah Springs Tuff, Southeastern Great Basin Ignimbrite Province". Diss., CLICK HERE for online access, 2008. http://contentdm.lib.byu.edu/ETD/image/etd2586.pdf.

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Lahey, Philip Ashley. "La Réponse religieuse de W.H. Auden". Lille 3 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37606837c.

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Chong, Kock-yuen Raphael y 莊國源. "Redevelopment of Wah Yan College Hong Kong". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B31982347.

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陳石麟 y Shek-lun Conan Chan. "Adaptable housing in Hing Wah Estate II". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31985075.

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Chan, Shek-lun Conan. "Adaptable housing in Hing Wah Estate II". Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25948453.

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Chong, Kock-yuen Raphael. "Redevelopment of Wah Yan College Hong Kong". Hong Kong : University of Hong Kong, 1995. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25946092.

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Libros sobre el tema "WBH"

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Soedjarwadi, Kusno. Woh bukan wah: Catatan perjalanan hidup aktor Kusno Soedjarwadi. Jakarta: Perhimpunan Gerak Indonesia Mandiri, 2005.

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Lafond, Jérôme. Poèmes du wah-wah. Montréal: Marchand de feuilles, 2003.

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Miriam, Cohen. Wah-wah!: A backpack baby story. New York: Star Bright Books, 2003.

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Harold, Bloom, ed. W.H. Auden. New York: Chelsea House Publishers, 1986.

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Ahmad, Amna Iqbal. Woh shehar. Rawalpindi: Amna Iqbal, 1986.

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W.H. Auden. London: Greenwich Exchange, 1997.

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Wah, Bernard. Bernard Wah. Port-au-Prince, Haïti: Musée d'art haïtien, 1999.

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Sarah, Andrew, ed. Wah hey! Peterborough: Poetry Now, 1995.

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Stan, Smith. W.H. Auden. Oxford, OX, UK: Blackwell, 1985.

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author, Brachmann Christoph y Engelberg Meinrad von author, eds. WBG-Architekturgeschichte. Darmstadt: WBG, Wissenschaftliche Buchgesellschaft, 2013.

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Capítulos de libros sobre el tema "WBH"

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Gautherie, Michel. "WBH and Chemotherapy". En Whole Body Hyperthermia: Biological and Clinical Aspects, 29–46. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-84596-3_4.

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Gautherie, Michel. "WBH Animal Studies". En Whole Body Hyperthermia: Biological and Clinical Aspects, 63–64. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-84596-3_6.

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Heckel-Reusser, S. "Whole-Body Hyperthermia (WBH): Historical Aspects, Current Use, and Future Perspectives". En Water-filtered Infrared A (wIRA) Irradiation, 143–54. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92880-3_11.

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AbstractWhole-body hyperthermia (WBH), induced by passive heating, and active fever therapy induced by pyrogenic drugs, have been accepted as therapy of various diseases for many decades. However, the introduction of antibiotics and anti-inflammatory drugs caused the interest in this traditional therapy to decline. The development of modern WBH using infrared irradiation (IR) started in the 1960s.Three levels of hyperthermia differ fundamentally in practical implementation, mechanisms of action, and indications. Mild WBH is stress-free and aims mainly to muscle relaxation and increased perfusion in the locomotor system. Fever-range whole-body hyperthermia (FRWBH) requires a more extensive nursing care due to major thermoregulatory stress. FRWBH is applied for stimulation of anti-tumor immune responses and for anti-inflammatory effects in case of chronic inflammation. Moreover, anti-depressive effects of FRWBH could recently be shown. Extreme WBH needs an intensive care environment and aims to the direct damage of cancer cells or therapy-resistant pathogens. In general, inconsistent effects of WBH on blood perfusion must be taken into account if combined with medication.Two commercially available medical WBH devices both use water-filtered infrared-A (wIRA), but deviate in the practical implementation. Contraindications and the risk of side effects differ essentially between the three levels and must carefully be observed.
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Knobel, A., K. Hanusch, N. Auen, F. Rübener, S. Fischer, C. Borzim, A. Heinz y M. Schäfer. "Whole-Body Hyperthermia (WBH) in Psychiatry". En Water-filtered Infrared A (wIRA) Irradiation, 155–64. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92880-3_12.

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AbstractNew effective therapies for managing and treating psychiatric disorders such as major depression are urgently needed. Mood-enhancing effects have repeatedly been observed after whole-body hyperthermia (WBH) treatment in other medical disciplines, and there is promising evidence that WBH may be used in psychiatry for patients suffering from depressive disorders. Most importantly, a recent study demonstrated a significant, rapid, and partially lasting reduction of depressive symptoms in patients with major depressive disorder following a single session of water-filtered infrared-A induced whole-body hyperthermia (wIRA-WBH). Underlying mechanisms of actions may include immune modulation and serotonergic neurotransmission via warm-sensitive afferent thermosensory pathways to the midbrain.Current studies are focused on verifying these earlier findings and clarifying the mechanisms involved. Herein, we report on the establishment of WBH methodology in the psychiatry setting and provide our opinions on necessary future research.
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Gautherie, Michel. "WBH and Ionizing Irradiation". En Whole Body Hyperthermia: Biological and Clinical Aspects, 16–28. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-84596-3_3.

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Zschaeck, S. y M. Beck. "Whole-Body Hyperthermia in Oncology: Renaissance in the Immunotherapy Era?" En Water-filtered Infrared A (wIRA) Irradiation, 107–15. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92880-3_8.

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AbstractA short introduction to the use of whole-body hyperthermia (WBH) in oncology is provided. The main focus is on fever-range whole-body hyperthermia (FRWBH), since various preclinical studies have shown promising results using this approach. However, FRWBH has not been comprehensively investigated in clinical oncology trials. Having provided an overview on the methods to induce WBH, we will summarize preclinical and clinical data on the mode of action of FRWBH. The latter treatment positively affects the tumor micromilieu, especially by decreasing tumor hypoxia. It has the potential to enhance tumor-directed immune reactions and has proven anti-depressive and potential analgesic effects in patients without cancer. These pleiotropic effects align with good tolerability and high acceptability by patients. Given the available evidence, we argue that FRWBH should be investigated as an adjunct to modern cancer treatments in controlled clinical trials.
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Liu, Jiang-tao, Jin-sheng He y Yan Yu. "Wide-Azimuth, Broadband, and High-Density (WBH) 3D Interpretation Technology in B Oilfield of Niger". En Springer Series in Geomechanics and Geoengineering, 3386–94. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-2485-1_313.

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Lopp, Michael. "WFH". En Managing Humans, 209–12. Berkeley, CA: Apress, 2021. http://dx.doi.org/10.1007/978-1-4842-7116-2_34.

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Perttula, Timothy K. "Kee-Oh-Na-Wah’-Wah". En Ethnohistory and Archaeology, 89–109. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-1115-5_6.

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Beale, Roger. "Yes, minister – the privileged position of secretaries". En With the Benefit of Hindsight: Valedictory Reflections from Departmental Secretaries, 2004–11. ANU Press, 2012. http://dx.doi.org/10.22459/wbh.04.2012.01.

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Actas de conferencias sobre el tema "WBH"

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Cao, Xin, Chenyi Wang, Weiping Li y Qiangming Cai. "Design of A Novel Reconfigurable WBH Film Bulk Acoustic Resonator". En 2022 IEEE International Symposium on Antennas and Propagation and USNC-URSI Radio Science Meeting (AP-S/USNC-URSI). IEEE, 2022. http://dx.doi.org/10.1109/ap-s/usnc-ursi47032.2022.9887159.

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Pei, Jiang-yun, Yi Bao y Cheng Wang. "Contribution of WBH acquisition for reservoir geophysical prospecting on Songliao Basin". En SEG 2018 Workshop: Reservoir Geophysics, Daqing, China, 5-7 August 2018. Society of Exploration Geophysicists and the Chinese Geophysical Society, 2018. http://dx.doi.org/10.1190/rege2018-42.1.

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Umamaheswari, E., V. Kanchana Devi, A. Karmel, A. David Maxim Gururaj y Nebojsa Bacanin. "IoT-WBH - Internet of things based water bottle for better health". En 2ND INTERNATIONAL CONFERENCE ON MATHEMATICAL TECHNIQUES AND APPLICATIONS: ICMTA2021. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0109662.

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Wang, Wei, Jiangtao Liu, Xiaolin Lyu, Xin Hu, Yifan Li, Lamia Rouis, Mourad Khdhaouria y Aldrin Rondon. "Application of Deep Learning in First-Break Picking of Shallow OBN Data". En Gas & Oil Technology Showcase and Conference. SPE, 2023. http://dx.doi.org/10.2118/213983-ms.

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Abstract Summary As well known, the modeling of the near-surface from first-break plays a significant role on the sub-surface imaging, reservoir characterization, and monitoring. Small errors in first-break picking can greatly impact the seismic velocity model building, so it is necessary to pick high-quality travel times. Geoscientists from around the world continues trying their best to address the near-surface challenges. Due to the rapid development of high-efficiency acquisition technique, such as WBH (wide-azimuth, broadband and high-density) acquisition technique and blended source acquisition technique, the quantity of seismic data, especially 3D seismic exploration, has leapt from GB to TB(some to PB), which sets a big challenge for first-break picking. Traditional first-break picking methods can't meet the production. In recent years, with the development of computer capacity and algorithm, artificial intelligence has changed our lives in many ways. In seismic exploration, artificial intelligence, like deep learning, has played a more and more important role now, from fault prediction, attribute identification to velocity and first break picking. Generally, deep learning is a new neural network which has multiple hidden layers, mostly over 3 layers, compared with traditional neural network. Deep learning includes Deep Belief Network (DBN), Convolutional Neural Network (CNN), Recurrent Neural Network (RNN) and so on. In this paper, Convolutional Neural Network (CNN) and Recurrent Neural Network (RNN) have been combined for first-break picking in a large 3D OBN project of Caspian Sea. A high precision near seabed velocity model is built based on the auto-picked first break with tomography inversion, which provides a good solution for static problem of the survey.
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Mannucci, L., R. Redaelli y E. Tremoll. "EFFECTS OF BLOOD CELLS ON PLATELET AGGREGATION BY IMPEDANCE METHOD". En XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644870.

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To evaluate the effects of blood cells on the response of platelets to aggregating agents using whole blood impedance aggregometer, studies were carried out on whole blood (WB) of normal subjects and of patients with: polycythemia vera (PV), iatrogenic anemia (IA), primary thrombocytosis (PT), idiopathic thrombotic purpura (ITP), myeloid chronic leukemia (MCL), iatrogenic leukopenia (IL). The in vitro effects of red blood cells (RBC) and of white blood cells (WBC) on platelet rich plasma (PRP) aggregation were also evaluated. WB, PRP, WBC and RBC were prepared by conventional methods. Aggregation was performed using the impedance aggregometer (mod. 540, Chrono Log Corp). In normal subjects the concentration of collagen giving 50 % aggregation (AC50 ) found in PRP did not differ from that of WB, indicating that hematocrit values within the normal range did not appreciably affect platelet aggregation. The results obtained in WB of patients are summarized in the table: In vitro data showed that aggregation in prp in wb of normal subjects was related to the number of platelets present in the sample. RBC added to PRP significant reduced aggregation only when the RBC number was greater than 4.101 cells. No effect of WBC on collagen induced aggregation of PRP was observed, whereas significant inhibition was detected after ADP. It is concluded that the aggregation evaluated in WB with impedance method is dependent on the platelet number. Also, in vitro data and studies in WB of patients indicate that aggregation is significantly affected by the presence of cells other than platelets only in conditions of changes of the ratio between platelets and leukocytes and/or red cells.
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Barrett, Rob, Paul P. Maglio y Daniel C. Kellem. "WBI". En the first international conference. New York, New York, USA: ACM Press, 1997. http://dx.doi.org/10.1145/267658.267789.

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"WB5: mological measurements". En Proceedings of the 21st IEEE Instrumentation and Measurement Technology Conference. IEEE, 2004. http://dx.doi.org/10.1109/imtc.2004.1351193.

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"Session WB2: Spectroscopy". En 2005 IEEE Instrumentationand Measurement Technology Conference Proceedings. IEEE, 2005. http://dx.doi.org/10.1109/imtc.2005.1604269.

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"Session WB1: VLSI". En 2005 IEEE Instrumentationand Measurement Technology Conference Proceedings. IEEE, 2005. http://dx.doi.org/10.1109/imtc.2005.1604240.

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Muhammad, Abdur Rahman Malik, Usman Raja, Afaf Khalid y Sadia Jahanzeb. "The Effects of Involuntary Working From Home on Work-Life Balance, Work-Life Conflict, and Employees’ Burnout". En Economic and Business Trends Shaping the Future. Ss Cyril and Methodius University, Faculty of Economics-Skopje, 2023. http://dx.doi.org/10.47063/ebtsf.2023.0014.

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Before the COVID-19 pandemic, working from home (WFH) was supposed to be an HR practice to help employees attain a higher work-life balance. WFH has also been shown in previous research to reduce work-life conflicts. We suggest that these benefits of WFH are specific to voluntary WFH, and cannot be generalized to involuntary WFH, when it is not a choice, but a requirement. Unfortunately, research on involuntary WFH is extremely scarce. Using a time-lagged design, we collected data in three waves during the COVID-19 pandemic to test the effects of WFH on work life balance (WLB), work life conflict (WLC) and burnout. Results show that working from home directly and indirectly affects work-life balance, work-life conflict and burnout. The results also show that emotional exhaustion is the burnout dimension, which is most strongly influenced. Finally, results show that effects of WFH on burnout are mediated through WLB and WLC. These results significantly contribute to the research on working from home and burnout and present important directions for future research. In addition, the results help policy makers and managers in designing better WFH schemes and to develop conditions in which harmful effects of WFH are minimized.
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Informes sobre el tema "WBH"

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Alatalo, Philip, Rebecca J. Gast, Ann M. Tarrant y Rodrigo Zuñiga. Final cruise report and post-cruise sample processing R/V Gulf Challenger “GC Mixo 23-04”. Woods Hole Oceanographic Institution, noviembre de 2023. http://dx.doi.org/10.1575/1912/67241.

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A primary topic of interest in the field of biological oceanography is the role of planktonic productivity in the global carbon cycle. Over the past 20+ years, the traditional food web of algal production, zooplanktonic consumers and higher trophic level predators has been undergoing revision with a stronger understanding of the contributions made within the microbial loop. Of particular interest has been mixotrophy, the blurring of trophic mode assignments within the microbial eukaryotes. The overall goal of this cruise was to obtain a snapshot of the prevalence of mixotrophy within the Gulf of Maine and the potential contributions of mixotrophs to copepod diets. This cruise was meant to supplement the previous cruise (2303) during which we were only able to sample one station (WB7). The specific goal for this cruise was to sample WB2.
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Schuch, Klaus. Patterns of Geographical Mobility of Researchers from Six Western Balkan Countries in Regional and European Mobility Based Training Programmes. Fteval - Austrian Platform for Research and Technology Policy Evaluation, julio de 2021. http://dx.doi.org/10.22163/fteval.2021.516.

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The aim of this paper is to analyse the mobility of researchers from the six Western Balkan Countries, Albania, Bosnia and Herzego-vina, Kosovo*1, Montenegro, North Macedonia, and Serbia (abbr. WB6) within structured regional and European mobility programmes. We want to identify geographical patterns with a view on mobility-based training from the WB6 region to the EU, but also within the WB6 region. The following structured regional European programmes provide the basis for this comparative analysis • CEEPUS • ERASMUS + • Marie Skłodowska-Curie Actions (MSCA) • COST
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Shumway, Dean A., Kimberly S. Corbin, Magdoleen H. Farah, Kelly E. Viola, Tarek Nayfeh, Samer Saadi, Vishal Shah et al. Partial Breast Irradiation for Breast Cancer. Agency for Healthcare Research and Quality (AHRQ), enero de 2023. http://dx.doi.org/10.23970/ahrqepccer259.

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Objectives. To evaluate the comparative effectiveness and harms of partial breast irradiation (PBI) compared with whole breast irradiation (WBI) for early-stage breast cancer, and how differences in effectiveness and harms may be influenced by patient, tumor, and treatment factors, including treatment modality, target volume, dose, and fractionation. We also evaluated the relative financial toxicity of PBI versus WBI. Data sources. MEDLINE®, Embase®, Cochrane Central Registrar of Controlled Trials, Cochrane Database of Systematic Reviews, Scopus, and various grey literature sources from database inception to June 30, 2022. Review methods. We included randomized clinical trials (RCTs) and observational studies that enrolled adult women with early-stage breast cancer who received one of six PBI modalities: multi-catheter interstitial brachytherapy, single-entry catheter brachytherapy (also known as intracavitary brachytherapy), 3-dimensional conformal external beam radiation therapy (3DCRT), intensity-modulated radiation therapy (IMRT), proton radiation therapy, intraoperative radiotherapy (IORT). Pairs of independent reviewers screened and appraised studies. Results. Twenty-three original studies with 17,510 patients evaluated the comparative effectiveness of PBI, including 14 RCTs, 6 comparative observational studies, and 3 single-arm observational studies. PBI was not significantly different from WBI in terms of ipsilateral breast recurrence (IBR), overall survival, or cancer-free survival at 5 and 10 years (high strength of evidence [SOE]). Evidence for cosmetic outcomes was insufficient. Results were generally consistent when PBI modalities were compared with WBI, whether compared individually or combined. These PBI approaches included 3DCRT, IMRT, and multi-catheter interstitial brachytherapy. Compared with WBI, 3DCRT showed no difference in IBR, overall survival, or cancer-free survival at 5 and 10 years (moderate to high SOE); IMRT showed no difference in IBR or overall survival at 5 and 10 years (low SOE); multi-catheter interstitial brachytherapy showed no difference in IBR, overall survival, or cancer-free survival at 5 years (low SOE). Compared with WBI, IORT was associated with a higher IBR rate at 5, 10, and over 10 years (high SOE), with no difference in overall survival, cancer-free survival, or mastectomy-free survival (low to high SOE). There were significantly fewer acute adverse events (AEs) with PBI compared with WBI, with no apparent difference in late AEs (moderate SOE). Data about quality of life were limited. Head-to-head comparisons between the different PBI modalities showed insufficient evidence to estimate an effect on main outcomes. There were no significant differences in IBR or other outcomes according to patient, tumor, and treatment characteristics; however, data for subgroups were insufficient to draw conclusions. Eight studies addressed concepts closely related to financial toxicity. Compared with conventionally fractionated WBI, accelerated PBI was associated with lower transportation costs and days away from work. PBI was also associated with less subjective financial difficulty at various time points after radiotherapy. Conclusions. Clinical trials that compared PBI with WBI demonstrate no significant difference in the risk of IBR. PBI is associated with fewer acute AEs and may be associated with less financial toxicity. The current evidence supports the use of PBI in appropriately selected patients with early-stage breast cancer. Further investigation is needed to evaluate the outcomes of PBI in patients with various clinical and tumor characteristics, and to define optimal radiation treatment dose and technique for PBI.
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Joly, Kyle y Matthew Cameron. Caribou vital sign annual report for the Arctic Network Inventory and Monitoring Program: September 2022?August 2023. National Park Service, 2023. http://dx.doi.org/10.36967/2301773.

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Caribou (Rangifer tarandus) are an integral part of the ecological and cultural fabric of northwest Alaska. Western Arctic Herd (WAH) caribou roam over this entire region, including all 5 Arctic Network (ARCN) Inventory and Monitoring Program?s National Park units. Conservation of healthy caribou populations is specifically mentioned within the enabling legislation (Alaska National Interested Lands Conservation Act or ANILCA) for 3 of these park units and is of importance to subsistence hunters. Caribou are, by far, the most abundant large mammal in northwest Alaska and are famous for their long-distance migrations and large population oscillations. For these reasons, the ARCN parks chose WAH caribou as a Vital Sign for long-term monitoring. This report documents the monitoring results of this Vital Sign during its 14th year (September 2022?August 2023) of implementation. Results from the previous years of monitoring are also included for ease of comparison. Periodic syntheses of these data will be performed and reported on as appropriate. National Park Service (NPS) monitoring of the WAH is done in conjunction and cooperation with the Alaska Department of Fish and Game (ADFG). Thanks to a 2015 data sharing agreement, the report includes data funded by the ADFG dating back to September 2013. That particular year was chosen as it represents when the ADFG started deploying a substantial number of GPS collars on an 8-hour relocation schedule. Monitoring of the herd relies heavily on the use of Global Positioning System (GPS) radio telemetry collars that are capable of transmitting location data to a satellite. Given the extremely remote area that the WAH inhabits, this system provides the most efficient and accurate means to track individual caribou. These data are utilized to monitor the timing and location of migrations, as well as seasonal distributions of WAH caribou. Monitoring movement and the phenology of movement is perhaps the simplest means to track the influences of climate change, natural perturbations, development, and other potential impacts on a species?an analysis of which is outside the scope of this current report. This report also documents the NPS commitment and involvement with the WAH Working Group. The group is composed of important stakeholders including representatives for rural villages, sport hunters, conservationists, hunting guides, hunting transporters, and reindeer herders. In addition, all the agencies charged with managing the WAH, including the ADFG, NPS, US Fish and Wildlife Service (FWS) and Bureau of Land Management (BLM), serve as advisors to the group. Information gathered by the Caribou Vital Sign monitoring program are intended to supplement and complement existing data streams gathered by the other cooperating agencies and will be important in future management decisions.
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Al-Qadi, Imad, Jaime Hernandez, Angeli Jayme, Mojtaba Ziyadi, Erman Gungor, Seunggu Kang, John Harvey et al. The Impact of Wide-Base Tires on Pavement—A National Study. Illinois Center for Transportation, octubre de 2021. http://dx.doi.org/10.36501/0197-9191/21-035.

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Researchers have been studying wide-base tires for over two decades, but no evidence has been provided regarding the net benefit of this tire technology. In this study, a comprehensive approach is used to compare new-generation wide-base tires (NG-WBT) with the dual-tire assembly (DTA). Numerical modeling, prediction methods, experimental measurements, and environmental impact assessment were combined to provide recommendations about the use of NG-WBT. A finite element approach, considering variables usually omitted in the conventional analysis of flexible pavement was utilized for modeling. Five hundred seventy-six cases combining layer thickness, material properties, tire load, tire inflation pressure, and pavement type (thick and thin) were analyzed to obtained critical pavement responses. A prediction tool, known as ICT-Wide, was developed based on artificial neural networks to obtain critical pavement responses in cases outside the finite element analysis matrix. The environmental impacts were determined using life cycle assessment. Based on the bottom-up fatigue cracking, permanent deformation, and international roughness index, the life cycle energy consumption, cost, and green-house gas (GHG) emissions were estimated. To make the outcome of this research effort useful for state departments of transportation and practitioners, a modification to AASHTOWare is proposed to account for NG-WBT. The revision is based on two adjustment factors, one accounting for the discrepancy between the AASHTOware approach and the finite element model of this study, and the other addressing the impact of NG-WBT.
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Sunderland, Daniel, Mark Frederick Hoemmen y Christian Robert Trott. WBS STPR 04 Milestone 4 Report. Office of Scientific and Technical Information (OSTI), septiembre de 2018. http://dx.doi.org/10.2172/1481608.

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Trott, Christian Robert, Daniel Sunderland y Mark Frederick Hoemmen. WBS STPR 04 Milestone 4 Report. Office of Scientific and Technical Information (OSTI), septiembre de 2018. http://dx.doi.org/10.2172/1481609.

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Chauhan, Dharmistha y Swapna Bist Joshi. The World Bank in Asia: An assessment of COVID-19-related investments through a care lens. Care-responsive investments and development finance. Oxfam, diciembre de 2021. http://dx.doi.org/10.21201/2021.8182.

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International financial institutions (IFIs) and multilateral development banks have been playing a vital role in the response, recovery and ‘build back anew’ agenda from the COVID-19 pandemic. This is especially true of the World Bank Group (WBG), given its high volumes of committed investments across sectors, especially in low-income and vulnerable countries. This report presents, through case studies, how care-responsive the World Bank’s COVID-19-related investments have been in four member countries: Bangladesh, Cambodia, Nepal and the Philippines. It does so by using the Care Principles and Care-Responsive Barometer for IFIs to assess the nature of the WBG’s post-COVID recovery investments in these select countries, and by building evidence through a gender- and care-responsive budget review. The foundation for care inclusion has already been laid in WBG policy. The report uses this as an entry point to urge it to bring women’s unpaid, underpaid and paid work to the centre of the IFI agenda in order to move towards rebuilding a more gender-just and equal future.
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Fyfe, Caroline, Arthur Grimes, Shannon Minehan y Phoebe Taptiklis. Evaluation of the Warmer Kiwis Homes Programme: Full Report including Cost Benefit Analysis. Motu Economic and Public Policy Research, diciembre de 2022. http://dx.doi.org/10.29310/wp.2022.14.

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We evaluate the heat pump component of New Zealand’s Warmer Kiwi Homes (WKH) programme. The programme includes provision of heat pumps in living areas for eligible households (based on neighbourhood or income) that do not have suitable heating. It also includes installation of retrofitted insulation for houses with insufficient insulation. Staggered installation enables difference-in-difference estimates of impacts. Heat pump outcomes on which we focus include warmth and dryness of the living area, personal comfort and wellbeing, and electricity consumption. We combine the heat pump findings with prior findings related to insulation and heating to provide a set of cost benefit analyses of WKH. We find that household members overwhelmingly report increases in warmth, comfort and satisfaction with their home, and report decreases in condensation, damp and having to restrict heating due to cost. Some increase in life satisfaction is reported. Living areas of treated houses experience increases in temperature which are most pronounced around breakfast and evening times, and when outdoor temperatures are low. Houses also experience reduced humidity. Households that use the heat pump as an air conditioner experience reduced summer temperatures when outdoor temperatures are high. Winter electricity use falls in a house fitted with a heat pump relative to houses without a heat pump; savings are negligible at night and increase through the day, peaking at 5-9pm. No increase in electricity consumption is detected in summer. Benefit cost ratios (BCRs) are calculated using both wellbeing metrics and conventional health and energy components. The wellbeing-based BCR for the heat pump component (which places a high value on living in a warm home) is estimated at 7.49 while the more conventionally calculated (but overly conservative) BCR is 2.15. For the full WKH programme, the corresponding BCRs are calculated as 4.36 and 1.89.
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Trott, Christian Robert, ORNL Graham Lopez y LANL Galen Shipman. Kokkos Training Bootcamp WBS STPM12 Milestone 4. Office of Scientific and Technical Information (OSTI), septiembre de 2018. http://dx.doi.org/10.2172/1469759.

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