Tesis sobre el tema "Voice passages"
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Cosnier, Frédérique. "Passages de voix, essai d'anthropologie poétique, à partir des œuvres de Stéphane Bouquet, Christophe Manon et Frank Smith". Electronic Thesis or Diss., Paris 3, 2023. https://bsnum.sorbonne-nouvelle.fr/files/original/1338/6773/These_en_cours_de_traitement.pdf.
Texto completoTo enter poems through the concept of voice is to engage in a poetics of listening intently to bodies: the bodies which write, speak aloud, perform and translate, as well as the bodies of the reader and the spectator. When we undertake to deconstruct the metaphor of the voice and observe its forms of passage, we discover the decisive links that exist between language as a physical force and poetics as ethics and politics. The concept of the passage of voice gives rise to critical levers which involve other deconstructions, thereby changing the way we think about many dualisms. These latter usually prevent us from perceiving the relational activity of language, foremost among which is the opposition between oral and written language. To consider voices not as signatures – as stylistics or literary history often do – but as processes is to listen to the rhythms of subjectivations whose energy unfolds from the enunciative life of language, with their transformative or even emancipatory value. This implies discoveries about our conception of places and temporality, not as thematic or ontological categories, but as anthropological ones.This thesis explores three main forms of voice passages and sets out their issues and effects: movements of diffraction, spatialisation and presentation. To do so, it questions theoretical texts which focus on investigating the conceptual issues of voice, rhythm and subject (Meschonnic, Martin, Rabaté, Dessons, Bernadet), based on a main corpus (in the form of texts, performances and videos) made up of the protean works of the contemporary French poets Stéphane Bouquet, Christophe Manon and Frank Smith
BONNABRY, CELINE. "Mise au point et validation de modeles d'etude in vitro du passage percutane (doctorat : sciences pharmaceutiques)". Clermont-Ferrand 1, 1999. http://www.theses.fr/1999CLF1PP06.
Texto completoSeth, Anjali. "Effet de la rétention magnétique sur le passage d'un principe actif peu perméable à travers la membrane intestinale". Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066517/document.
Texto completoOral administration still remains the route of choice for the majority of pharmaceutical dosage forms due to higher patient comfort and reduced cost of treatment. One of the major drawbacks of using the oral route to deliver drugs is that these molecules need to cross biological membranes in order to pass to the bloodstream and reach their physiological target. A large number of drugs with high clinical potential have not yet been employed because of their limited bloodstream access. Therefore, there is a real need to develop new methodologies addressing the problem of low permeable drugs used in oral administration. In this work we studied retention using an external magnetic field as a mean to maintain magnetic carriers near the absorption site of the drug. It was proven that an effective retention can cause over-concentration of the drug near the intestinal membrane thus increasing its bioavailability. For this purpose, we designed magnetic carriers, first, at the lab scale, and then using industrial processes. Magnetic retention efficiency was subsequently studied using ex vivo and in vivo experiments. Pharmacokinetics studies coupled with imaging techniques showed that magnetic retention provided a threefold increase in drug bioavailability. Finally, it was shown that retention of magnetic carriers near the absorption window of the drug can lead to overconcentration of the drug and increased transport through intestinal membrane resulting in a higher absorbed fraction reaching the bloodstream
Maldonado, Marc. "VIBRATIONS DUES AU PASSAGE D'UN TRAMWAY : MESURES EXPÉRIMENTALES ET SIMULATIONS NUMERIQUES". Phd thesis, Ecole centrale de nantes - ECN, 2008. http://tel.archives-ouvertes.fr/tel-00356222.
Texto completoDemoy, Marina. "Etude de la capture et des modalites de passage de nanoparticules a l'interface sang-tissu splenique (doctorat : pharmacotechnie et biopharmacie)". Paris 11, 1998. http://www.theses.fr/1998PA114854.
Texto completoKemel, Kamilia. "Mécanismes de passage transcutané : étude des interactions nanoparticules / peau". Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS075.
Texto completoMany nanocarriers have been developed to improve the delivery of molecules into the skin. In this PhD thesis, we are interested in lipid-based Janus nanoparticles (JNP), an innovative galenic form characterized by the combination of two compartments of opposite chemical polarity, an aqueous compartment associated to a lipid compartment. The main aim was the characterization of JNP. ATR-FTIR spectroscopy allowed to identify an infrared descriptor to follow the physical stability of JNP in open air and over time. The same descriptor allowed to follow their behavior on the surface of the skin, and to note a significant penetration from 3 hours of application. AFM-IR has been shown to be a promising technique for studying the nanostructure of the human skin. In addition, it has shown that after 24 hours of application, JNP were accumulated in the first layers of the SC with a gradient in the deeper layers of the SC. However, it was not possible to conclude if they have penetrated in the intact or degraded form. JNP seem to have an influence on the cutaneous penetration of the hyaluronic acid, they allowed a significant increase of its penetration flux. The characterization of the lipophilic phase of JNP by different techniques (LC-MS, DLS, Cryo-TEM, X-ray diffraction...) allowed to better understand their instability at high temperatures (32°C - 43°C)
Wu, Wen. "Développement de nanoparticules composites polymériques de S-nitrosoglutathion dédiés au traitement oral des maladies cardiovasculaires". Thesis, Université de Lorraine, 2015. http://www.theses.fr/2015LORR0115.
Texto completoAs a physiologic nitric oxide (NO) donor, S-nitrosoglutathione (GSNO) has potential therapeutic application for the treatment of cardiovascular disease (CVD). With a longer in vivo half-life than NO, GSNO is still sensitive to many factors leading to poor applicability. This study aimed at the development of nanocomposite particles (NCP) based on synthetic polymeric nanoparticles encapsulating GSNO (GSNO-NP) embedded in a polysaccharidic matrix for oral delivery of GSNO. Although GSNO-NP, with a high encapsulation efficiency, showed an in vitro burst release, they succeeded in the preservation of GSNO stability and bioavailability for smooth muscle cells as they delayed in vitro protein S-nitrosation (NO biomarker) until 18 h. Therefore, to reach the sustained release, GSNO-NP were embedded in a matrix of alginate (a), chitosan (c) or a blend (acNCP). GSNO-acNCP with high encapsulation efficiency (76%) and an in vitro release until 24 h, promoted the highest permeation rate of GSNO through an intestinal barrier model (Caco-2). With this daily oral treatment compatibility Wistar Rat pretreatment by gavage with GSNO-acNCP 17 h before aorta removal decreased the maximal contractile effect induced by phenylephrine (PHE) on isolated aortic rings. Furthermore, the N-acetylcysteine (a thiol displacing NO stores from tissues) produced the relaxation of PHE precontracted aortic rings, proving NO storage in the vessel wall. By increasing the residence time in the gastrointestinal tract thus promoting GSNO crossing through the intestinal barrier, GSNO-acNCP induced a long lasting effect (17 h after administration) through NO storage in vessels
Bol, Ludivine. "Conception d’un microsystème pour l’évaluation du passage de biomolécules à travers la barrière pulmonaire". Thesis, Paris 11, 2014. http://www.theses.fr/2014PA112118/document.
Texto completoThe pulmonary route is of increasing interest for the systemic administration of therapeutic proteins and peptides, still largely administered parenterally. A microdevice was designed to facilitate and accelerate the in vitro screening studies of various active biomolecules and to select the most suitable formulations for penetration through the lung epithelium, in order to select the best candidates for an administration via the lungs. Organized in two distinct configurations, this microdevice allows as a first step the culture of tight polarized bronchial epithelial barriers (Calu-3 cells) in 7 days in 1 mm² microwells, without the need for medium renewal or the use of an external apparatus. A simple manufacturing technique was developed and glass culture platforms containing 12 parallel microwells can be obtained in a standardized manner. The ability of molecules to cross the pulmonary barrier is then performed in the second configuration of the microdevice, which is dedicated to the permeability measurement of the tight epithelial Calu-3 barriers cultured in microwells. Among the different candidates studied (nanoparticules and biomolecules), the pulmonary barrier permeability regarding PLGA nanoparticules coated with chitosan and regarding insulin has been successfully demonstrated. Finally, capillary electrophoresis with laser induced-fluorescence (CE-LIF), a technique compatible with the low volumes handled in this microdevice, has been exploited for insulin detection and quantification after its transport across the miniaturized pulmonary barriers. To this end, insulin was either FITC-labeled or complexed with a fluorescent antibody or aptamer. Currently, only the derivatization method can be used for a quantification purpose, but the use of an aptamer to indirectly quantitate insulin has shown encouraging results
Iffli, Sandie. "L'injonction surmoïque chez le criminel non psychotique". Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM3054.
Texto completoFrom our clinical experience with prison inmates, our research work proposes a theoretical paradigm of the concept of acting-out in relation with the superego instance. The purpose is thus to bring out the metapsychological stakes and issues of the superego concept as they appear in the clinical approach of the acting-out, and more specifically in relation with the criminal act, while tracing back the conditions of its theoretical elaboration. Even if the foundations that Freud laid is essential to our reflection, the kleinian concepts of primitive superego and of paranoid-schizoid position will be far more precious to us in this endeavour to reflect on the reappearance of certain modes of functioning which are under the supremacy of a particularly cruel and destructive superego. This aspect, which Lacan has reformulated with his view of an imperative superego, will provide the basis for our discourse. While the superego instance is first identified through its function of moral consciousness, as a legislating instance, there also exists a more paradoxical double polarity whereby the reverse side of the Law is expressed through a ferocious and cruel injunction to have enjoyment (“jouissance”). Within this perspective, the criminal acting-out appears like the irrepressible response to the injunction of a strong Superego pushing to commit harsh and virulent actions. This thesis notably insists on the criminal act seen as a last resort. A resort which aims at releasing oneself from the position where one has become the object of the Other's “jouissance”, while one tries, at the same time, to be a subject
Bol, Ludivine. "Conception d'un microsystème pour l'évaluation du passage de biomolécules à travers la barrière pulmonaire". Phd thesis, Université Paris Sud - Paris XI, 2014. http://tel.archives-ouvertes.fr/tel-01061867.
Texto completoBussières, Manon. "De la voie de passage au chemin public : le réseau routier et ses représentations dans la province de Québec : l'exemple du Centre-du-Québec, 1706-1841". Thèse, Université du Québec à Trois-Rivières, 2009. http://depot-e.uqtr.ca/1283/1/030105331.pdf.
Texto completoCoutable, Jocelyn. "Contribution à l'étude du passage percutané d'un inhibiteur calcique de la famille des phényl-dihydropyridines : développement et optimisation d'une forme topique". Paris 5, 1991. http://www.theses.fr/1991PA05P618.
Texto completoBaati, Tarek. "Etude du passage membranaire de solutions huileuses du [60] fullerène administrées par voie orale : action sur le stress oxydatif dans un model expérimental d’intoxication par le CCI4 chez le rat". Paris 11, 2009. http://www.theses.fr/2009PA114823.
Texto completoThe objective of this thesis was to study the effects of an oily solution of [60]fullerene on oxidative stress in an experimental model in rats. The results obtained show that the fullerene can be absorbed through the digestive tract and that these effects are notable, even at doses of the order of several milligrams per kilogram of body weight
Cartaya, Jorge E. "Listening/Reading for Disremembered Voices: Additive Archival Representation and the Zong Massacre of 1781". FIU Digital Commons, 2017. http://digitalcommons.fiu.edu/etd/3187.
Texto completoMahmoud, Salim. "La structure narrative dans la trilogie de ʼAḥlām Mustaġānimī, et la présence de l’Algérie dans des histoires d’amour". Thesis, Lyon, 2020. http://www.theses.fr/2020LYSE3045.
Texto completoThis thesis is an analysis of the trilogy of ʼAḥlām Mustaġānimī, one of the first Algerian authors in Arabic with formal analysis and the works of Genette.The introduction discusses the methodology and the issue. How are the novels woven into a trilogy and why have they been so popular with the Arabic-speaking readership? Which leads to another: how Algerian history is included in the trilogy. The first part shows that these novels are a reflection of Mustaġānimī's life and his commitment, through the dedications and the Arabic language of which generations have been deprived. The second part uses the tools of the formal approach to determine the mechanism of suspense by disassembling the narrative text into the constituent elements of the main story, the love story, and its interruptions. It shows ʼAḥlām Mustaġānimī's great sensitivity to the place of women and to Algerian politics before and after independence. The last part, with intertextualities and linguistic styles, analyzes the text, and the poetry of its writing. This mastery of the Arabic language by Mustaġānimī is one of the causes of his success in the Arabic-speaking readership. This thesis shows the interest of these methods of analysis, explaining and objectifying the feelings of the reader. Finally, Mustaġānimī finds himself in the implicit protagonist of the trilogy, which is therefore an “intrusion” into the life of the writer
Manabe, Nkateko Lorraine. "The silenced voice of initiated Venda women". Thesis, 2010. http://hdl.handle.net/10530/595.
Texto completoThe lives of individuals in all societies are a series of passages from one age to another and from one occupation to the other. Among the Vhavenda, there are fine distinctions among age or occupational groups and progression from one group to the next is accompanied by special rituals enveloped in ceremonies which involve actions that are clearly regulated and guarded so that the entire society suffer no discomfort or injury. The research explores and describes the lived experiences of Vha-Venda initiated women in the rural areas of Mashau, Mashawana and Shayandima village in Limpopo Province, South Africa. The perception that transition practices, otherwise known as initiation rituals or rites of passage, are only practiced in the ‘traditional’ societies because it is believed to be where the culture is embedded. This study draws on qualitative research principles based on the ethnographic approach. This research explores and describes the lived experiences of initiation of Venda women that is practiced and currently being implemented in the three villages that is, Mashau, Mashawana and Shayandima village in Limpopo Province, South Africa. As a result, this study is informed by the qualitative data gathered during the initial stages of the research with the assistance of research guides. The core material in this study emerges from in depth, semi-structured interviews conducted during individual interviews and focus group interviews with fifteen initiated women and two research guides between the age of thirty and sixty. The research guides, with special knowledge of the culture assisted the researcher on the process and activities of the initiation and also informed the researcher about the venues where certain rituals take place and also assisted in translation of certain phrases for clarification. In compliance with research ethics, the identities of the respondents remain confidential through the use of pseudonyms. The research concludes that the lived experiences of women initiation are private and one is strictly prohibited to talk about them, especially with uninitiated women. The aim is to portray the traditional social and cultural ritual proposed to be learnt and preserved. In this study, the researcher’s findings are that: Conformity, compliance and obedience with the initiation rituals can save a person from embarrassment in Limpopo Province where initiation is practiced. Participants reported that women are silenced and forbidden to talk about initiation outside ‘dombani’ with the uninitiated women. They reported that the initiation ritual is secret and thus a taboo to talk about it. Initiates are prohibited to disclose what happens during the initiation process. In contrast, uninitiated women viewed the ritual as barbaric and promiscuous. The initiated indicated that they were forced to attend because of fear of rejection, discrimination and isolation by the community. Other participants agreed to have attended for the sake of acceptance, though they believed to have gained knowledge about understanding womanhood. Most of the women mentioned that although it was some years that they had attended the initiation school, they still carried the burden of anger, shame, humiliation, frustration, low-self esteem, sense of helplessness and lack confidence and still find it hard to share their experiences or talk about them. The researcher concurs with the participants and Stayt (1968) that initiated women are denied freedom of expression. It is sticky prohibited to talk or share the initiation experiences with the non- initiated let alone discuss it outside dombani. Thereby, the aim, and its concomitant 4 objectives, have been thoroughly explored and achieved.
Yilmaz, Kamil. "Individual Disengagement of "Turkish Penitents" from Political Violence as Rite of Passage: Voices from the Cracks of Social Structure". Thesis, 2012. https://doi.org/10.7916/D8CZ3DHX.
Texto completoDaigneault, Anna Luisa. "An ethnolinguistic study of the Yanesha’ (Amuesha) language and speech community in Peru’s Andean Amazon, and the traditional role of Ponapnora, a female rite of passage". Thèse, 2009. http://hdl.handle.net/1866/4055.
Texto completoThe Yanesha’ language is spoken on the edges of two worlds, the Andes and the Amazon, in southcentral Peru. Ethnolinguistic fieldwork was carried out among the Yanesha’ people in May-August 2008 to learn about their language and the possible factors leading to its endangerment. This thesis examines the unique linguistic features of Yanesha and its place within the Arawak language family. It also discusses a puberty ritual that plays an important role in preserving musical and linguistic heritage among Yanesha’ women: the ponapnora female initiation ritual.
Thesis written in co-mentorship with Richard Chase Smith Ph.D, of El Instituto del Bien Comun (IBC) in Peru. The attached file is a pdf created in Word. The pdf file serves to preserve the accuracy of the many linguistic symbols found in the text.