Tesis sobre el tema "Understanding risk"
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Greer, Desmond. "Software engineering risk : understanding and management". Thesis, University of Ulster, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326127.
Texto completoWagner, Alice Elizabeth 1980. "Understanding risk in a biopharmaceutical portfolio". Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/68469.
Texto completoCataloged from PDF version of thesis. "Pages 65-70 contain illegible text. This is the best copy available"--P. after t.p.
Includes bibliographical references (p. 63-64).
Investors have difficulty funding the life sciences because of the high risks involved in research and development and commercialization of new products. Risk in the biopharmaceutical industry is the result of scientific, regulatory and economic uncertainty. The nature of the biopharmaceutical industry introduces many challenges. Each of these challenges incorporates a measure of risk into drug development. The level of understanding of technical success interdependencies has not been fully investigated. These interdependencies (correlations) could lead to an overall greater risk to the company's portfolio than previously expected. A better understanding of the risks that lead to success or failure in drug development might encourage more investment in the life sciences and specifically in the biopharmaceutical industry, and a greater awareness of the correlations between risks and products might lead to more informed decision making on a biopharmaceutical portfolio leading increased productivity. A dataset was collected from Thomson Reuters. The dataset is the oncology portfolio from a biopharmaceutical company, Genentech Inc. Logistic regression was used to determine if any of the defined variables contributed to the success or failure of the oncology products. The chi-square value was 7.738 with the degrees of freedom equal to 5 and with a p-value of 0.17. Therefore, none of the variables significantly contributed to the outcome. More research should be performed in this area in order to better understand the risk in a biopharmaceutical portfolio.
by Alice Elizabeth Wagner.
S.M.
Burkhart, Katelyn A. "Understanding vertebral fracture risk in astronauts". Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/122344.
Texto completoThesis: Ph. D. in Medical Engineering and Bioastronautics, Harvard-MIT Program in Health Sciences and Technology, 2019
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references.
In spaceflight, the loss of mechanical loading has detrimental effects on the musculoskeletal system. These muscular changes will likely affect spinal loading, a key aspect of vertebral fracture risk, but no prior studies have examined how spinal loading is affected by long duration spaceflight. Moreover, the effect of spaceflight on vertebral strength has not been determined, despite reports of significant vertebral trabecular bone loss in long-duration astronauts. Thus trunk muscle and vertebral bone changes and their impact on risk of injury following long-duration spaceflight remain unknown. This is of particular concern for NASA's planned Mars missions and return to Earth after prolonged deconditioning. Our lab has developed a musculoskeletal model of the thoracolumbar spine that has been validated for spinal loading, but has not yet been extended to maximal effort activities or full-body simulations.
Thus, the overall goal of this work consisted of two main sections: 1) address the knowledge gap regarding spaceflight and post-flight recovery effects on trunk muscle properties, vertebral strength, compressive spine loading and vertebral fracture risk, and 2) extend our musculoskeletal modeling work into maximal effort simulations in an elderly population and create a full-body scaled model to investigate reproducibility of spine loading estimates using opto-electronic motion capture data. Whereas deficits in trunk muscle area returned to normal during on-Earth recovery, spaceflight-induced increases in intramuscular fat persisted in some muscles even years after landing. Similarly, spaceflight led to a decrease in lumbar vertebral strength that did not recover even after multiple years on Earth.
To gain insight into the effect of spaceflight on vertebral fracture risk, we created subject-specific musculoskeletal models using an individual's height, weight, sex, muscle measurements, and spine curvature. We found that compressive spine loading was minimally affected by spaceflight and that vertebral fracture risk, calculated as a ratio of vertebral load to strength, was slightly elevated post-flight and remained elevated during readaptation on Earth. Additionally, we focused on the development of additional musculoskeletal modeling tools. Using maximal effort model simulations, we estimated trunk maximum muscle stress in an elderly population, and this critical parameter in musculoskeletal modeling will assist with more detailed model creation. Lastly, we found excellent reliability of spine loading estimations from opto-electronic marker data.
by Katelyn A. Burkhart.
Ph. D. in Medical Engineering and Bioastronautics
Ph.D.inMedicalEngineeringandBioastronautics Harvard-MIT Program in Health Sciences and Technology
Lauder, Michael Alan. "Conceptualisation in Preparation for Risk Discourse: A Qualitative Step toward Risk Governance". Thesis, Cranfield University, 2011. http://dspace.lib.cranfield.ac.uk/handle/1826/6793.
Texto completoNorton, Vincent G. 1969. "Understanding risk sharing mechanisms for brownfields redevelopment". Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/69388.
Texto completoLeask, J. "Understanding Immunisation Controversies". Thesis, The University of Sydney, 2002. http://hdl.handle.net/2123/12503.
Texto completoVadeboncoeur, Nathan Noel. "Knowing climate change : modelling, understanding, and managing risk". Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/50777.
Texto completoScience, Faculty of
Resources, Environment and Sustainability (IRES), Institute for
Graduate
Griffin, Jonathan Michael. "Understanding and assessing lodging risk in winter wheat". Thesis, University of Nottingham, 1998. http://eprints.nottingham.ac.uk/13410/.
Texto completoBrakenhoff, Brittany R. "Understanding the HIV Risk Behaviors of Homeless Youth". The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1523839282654593.
Texto completoZale, Andrew. "PARENTAL UNDERSTANDING OF ANESTHESIA RISK FOR DENTAL TREATMENT". VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/2697.
Texto completoDresser, Paul. "Understanding prevent policing through dispositif and reflexive risk". Thesis, Manchester Metropolitan University, 2015. http://e-space.mmu.ac.uk/595496/.
Texto completoMcNaughton, Carol Corinne. "Understanding transitions through homelessness in a risk society". Thesis, Connect to e-thesis, 2007. http://theses.gla.ac.uk/969/.
Texto completoPh.D. thesis submitted to the Faculty of Law, Business and Social Science, University of Glasgow, 2007. Includes bibliographical references. Print version also available.
Lana, Olubunmi. "From risk to reason : understanding young people's perception of HIV risk in South Africa". Thesis, University of York, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538635.
Texto completoStuder, Bettina. "Understanding risky choice : the psychophysiological and neural correlates of human decision-making under risk". Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610278.
Texto completoHorner, William J. C. "The risk, the slip and the understanding of sculpture". Thesis, Royal College of Art, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487370.
Texto completoHunter, Alasdair. "Quantifying and understanding the aggregate risk of natural hazards". Thesis, University of Exeter, 2014. http://hdl.handle.net/10871/15719.
Texto completoSajeev, Gautam. "Mediation Analysis in Understanding Mechanism of Alzheimer’s Disease Risk". Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:16121154.
Texto completoEpidemiology
Sampson, Christopher Charles. "Improving understanding of flood risk in the insurance industry". Thesis, University of Bristol, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738192.
Texto completoDawson, Ian G. J. "Understanding and improving people's judgments of synergistic risks". Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/210547/.
Texto completoEmilien, Regine Alexandra. "Understanding the HIV Risk Behaviors in Haiti:A Rural-Urban Comparison". Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/iph_theses/37.
Texto completoHunter, Amanda Louise. "Firefighters and acute myocardial infarction : understanding mechanisms and reducing risk". Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33254.
Texto completoMast, Maria R. "Understanding Risk Factors in Opioid Addiction in Franklin County, Ohio". Franklin University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=frank1616006262553234.
Texto completoStephanie, Kozina. "Understanding the Relationship of Trust and Risk in Online Shopping". Cleveland State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=csu1336522674.
Texto completoMori, Candace Lynn. "Understanding the Experience of Osteoporosis Risk in Bariatric Surgical Patients". Kent State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=kent1573669680874186.
Texto completoHamad, Anas Ahmad E. A. "Evaluating, understanding and managing medication incidents with high-risk antibiotics". Thesis, King's College London (University of London), 2015. http://kclpure.kcl.ac.uk/portal/en/theses/evaluating-understanding-and-managing-medication-incidents-with-highrisk-antibiotics(7e31a512-b468-402c-a110-0b5903a6fab8).html.
Texto completoWahl, Elizabeth R. "Older adults' understanding of cardiovascular risk and preventive medication benefit". [New Haven, Conn. : s.n.], 2008. http://ymtdl.med.yale.edu/theses/available/etd-12092008-165627/.
Texto completoAlvarez, Amanda Milena. "Risk Acceptance and Contentious Politics: An Understanding of Protest Activity". Diss., Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/581245.
Texto completoPh.D.
What are the individual characteristics which motivate individuals to participate in contentious politics? This dissertation claims that risk acceptance as a psychological concept allows us to understand the individual predispositions that impact participation in protest activity. This dissertation project is significant to the field of political science in that it theorizes about the characteristics that make individuals risk acceptant and utilizes risk acceptance in the study of contentious politics, which has not been done before. I import claims from social psychology to highlight how lack of completion of several life cycle markers-which I name risk weights, such as marriage, parental status, and educational attainment amongst others-make individuals more risk acceptant. Once these risk weights are mapped onto risk, it allows one to determine and explain when protest activity is likely to occur. My dissertation uses a mixed-method approach to examine the relationship between risk acceptance and contentious politics. It is divided into the following components: one measure for risk acceptance, two online experiments, and field interviews in Chile. There are two main claims that this project posts: The first is that high levels of risk acceptance correspond with higher likelihood of participation in different forms of contentious political events, with case study work focusing on protest activity in Latin America. The second claim is that risk acceptance is a function of risk weights. The more risk weights that an individual has, the less likely they are to participate in contentious politics. Conversely, the fewer risk weights that an individual has, the more likely they are to participate in contentious political action. One of the important contributions of my work is that it treats risk acceptance as a purely psychological factor, one that is stable and only changes in accordance with risk weights, but that is not impacted by the context in which individuals are embedded. This means that the decision to participate or not participate in contentious political action is a function of the interaction between risk acceptance and some other contextual factors which are beyond the scope of my present research. This dissertation aims to identify the likelihood of participation for any individual. Social psychology has been underutilized in the study of contentious politics and can provide insights into why individuals self-select into these movements. In the context of worldwide mass mobilization, this allows us to understand the underlying individual psychological predispositions that lead to mass mobilizations and waves of mobilizations. Examining how these psychological mechanisms manifest themselves into various forms of contentious politics has important potential applications for the study of contentious politics.
Temple University--Theses
Cheah, Sern Yih. "Understanding the risk and functional importance of schizophrenia genetic factors". Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/101340/1/Sern%20Yih_Cheah_Thesis.pdf.
Texto completoNebergall, Michelle L. "Understanding Perceptions Of Risk Among Youth In A South African Township". Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1403102512.
Texto completoTRAORE, Fatoumata. "Understanding Sexual Risk Behaviors among Persons Living with HIV/AIDS in Abidjan, Cote d’Ivoire". Case Western Reserve University School of Graduate Studies / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=case1112511160.
Texto completoMeyer, Roman. "Understanding Options Mispricing An Empirical Analysis of Volatility Risk Premia and Earnings Disagreement as Priced Risk Factors /". St. Gallen, 2008. http://www.biblio.unisg.ch/org/biblio/edoc.nsf/wwwDisplayIdentifier/02601144002/$FILE/02601144002.pdf.
Texto completoOber, Allison J. "Understanding the relationship between perceived partner risk behaviors and unprotected sex among low-income, high-risk women". Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1934943111&sid=16&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Texto completoLee, Daniel. "Understanding views of risk, a case study of Swan Hills, Alberta". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0019/MQ47957.pdf.
Texto completoHospers, Harm. "Homosexual men and the HIV epidemic understanding and changing risk behavior /". [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 1999. http://arno.unimaas.nl/show.cgi?fid=6881.
Texto completoEmilien, Régine Alexandra. "Understanding the HIV risk behaviors in Haiti a rural-urban comparison /". unrestricted, 2008. http://etd.gsu.edu/theses/available/etd-04302008-125002/.
Texto completoTitle from file title page. Richard Rothenberg, committee chair; John Beltrami, Michael Eriksen, committee members. Electronic text (111 p.) : digital, PDF file. Description based on contents viewed Aug. 22, 2008. Includes bibliographical references (p. 65-73).
Mason, Daniel. "Understanding and recall of health risk information presented graphically and interactively". Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612727.
Texto completoMcKay, Sarah Michele. "Understanding Organic Prices: An Analysis of Organic Price Risk and Premiums". Thesis, Virginia Tech, 2016. http://hdl.handle.net/10919/71677.
Texto completoMaster of Science
Sasota, Jo A. "Understanding when interdependence with other people decreases or increases risk-taking". The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1305839223.
Texto completoLai, Pui Man Rosalind. "Understanding the Genetic Susceptibility and Epidemiologic Risk Factors of Intracranial Aneurysms". Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:15821583.
Texto completoCreech, Christina, Taylor Lacey, Elizabeth Patton, Brittany Jamison y (Guntupalli) Chaya D. Nanjundeswaran. "Understanding Role of Occupational Risk Factors in Voice Problems of Teachers". Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/1771.
Texto completoDavis, Heather A. "DO BULIMIC BEHAVIORS INCREASE SHAME? TOWARD AN UNDERSTANDING OF TRANSDIAGNOSTIC RISK". UKnowledge, 2019. https://uknowledge.uky.edu/psychology_etds/163.
Texto completoJagelka, Tomáš. "Preferences, Ability, and Personality : Understanding Decision-making Under Risk and Delay". Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLX028/document.
Texto completoPreferences, ability, and personality predict a wide range of economic outcomes. I establish a mapping between them in a structural framework of decision-making under risk and delay using unique experimental data with information on over 100 incentivized choice tasks for each of more than 1,200 individuals.I jointly estimate population distributions of risk and time preferences complete with their individual-level stability and of people’s propensity to make mistakes. I am the first to do so using the Random Preference Model (RPM) which has been recently shown to have desirable theoretical properties over previously used frameworks. I show that the RPM has high internal validity. The five estimated structural parameters largely dominate a wide range of demographic and socio-economic variables when it comes to explaining observed individual choices between risky lotteries and time-separated payments.I demonstrate the economic and econometric significance of appending shocks directly to preferences and of incorporating the trembling hand parameter - their necessary complement in this framework. Mistakes and preference instability are not only separately identified but they are also linked to different cognitive and non-cognitive skills. I propose a Rationality Index which condenses them into a single indicator predictive of welfare loss.I use a factor model to extract cognitive ability and Big Five personality traits from noisy measures. They explain up to 50% of the variation in both average preferences and in individuals’ capacity to make consistent rational choices. Conscientiousness explains 45% and 10% respectively of the cross-sectional variation discount rates and risk aversion respectively as well as 20% of the variation in their individual-level stability. Furthermore, risk aversion is related to extraversion and mistakes are a function of cognitive ability, task design, and of effort. Preferences are stable for the median individual. Nevertheless, a part of the population exhibits some degree of preference instability consistent with imperfect self-knowledge.These results have implications both for specifying reduced form and structural economic models, and for explaining inequality and the inter-generational transmission of socioeconomic status
An, Gie Yong. "A Social-Ecological Approach to Understanding Natural Disaster Preparedness and Risk Perception amongst Immigrants: A Multi-Method Inquiry". Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/37007.
Texto completoBirchmore, Ian. "Understanding public sector risk : a study into the nature and assessment of strategic risk in English local authorities". Thesis, University of Warwick, 2014. http://wrap.warwick.ac.uk/65694/.
Texto completoBurnett, Emma Jane. "Understanding risk perceptions and responses of the public, healthcare professionals and the media : the case of Clostridium difficile". Thesis, University of Dundee, 2015. https://discovery.dundee.ac.uk/en/studentTheses/ce827691-9027-449b-98ae-50b32c44c14c.
Texto completoSayah, Mabelle. "Understanding some new Basel III implementation issues for Lebanese Commercial Banks". Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1150/document.
Texto completoThis thesis aims at providing Bank Audi with an updated tool to understand and investigate in given risk types encountered in their portfolios and the way Basel suggests computing their capital charges. International regulator is constantly changing and modifying previously used approaches to enhance the reflection of the market and banking sector risks. The recent financial crisis played a major role in these reforms, in addition the situation of Bank Audi and the markets it is operating in, represent certain specifications that should be accounted for. The work handles interest rate risk in the trading book, Counterparty Credit Risk faced with derivatives along a closer look on the Credit Valuation Adjustment topic and the incorporation of Wrong Way Risk. The first part discusses the new Fundamental Review of the Trading Book: focusing on the general interest rate risk factor, the paper compared Basel’s Sensitivity Based Approach (SBA) capital charge to more traditional approaches of VaR using several models such as Generalized Auto Regressive Conditional Heteroscedasticity (GARCH), Principal Components Analysis (PCA), Independent Components Analysis (ICA) and Dynamic Nelson Siegel. Application on portfolios with zero coupon bonds of different sovereigns revealed the divergence in results between stable markets (such as France and Germany), less stable (such as the USA) and emergent markets (such as Turkey). The second part is dedicated to the Counterparty Credit Risk. A new capital charge methodology was proposed by Basel and set as a standard rule in 2014: the Standardized Approach for Counterparty Credit Risk (SA-CCR). Applying this approach on different derivatives portfolios, we compared it to internal models. The internal methodologies incorporated historical estimations and future projections based on Vasicek and GARCH models. Different hedging cases were investigated on EUR and USD portfolios. The impact of each hedging technique and the difference between IMM and the standardized methods were highlighted in this work: without hedging, the internal approach amends 80% of the standardized capital whereas, in general, the hedging is encouraged more under the standardized approach relatively to its capital reduction under the internal model. The third part remains a part of the Counterparty Credit Risk however, the main focus in this work is the Credit Valuation Adjustment. This topic was neglected in terms of capital charge earlier but due to its important impact is now incorporated as a capital charge amended when no central clearing is put in place when dealing with derivatives. We focus on the regulatory approaches of capital computation, comparing both accepted approaches based on portfolios of interest rate swaps held with investment grade sovereigns. An incorporation of the Wrong Way Risk is another addition in this work: using Error Correction Models we were able to reflect the impact of the correlation between the exposure and the credit quality of the investment grade sovereign we are dealing with. Based on such results, a suggestion of a re-calibrated standardized approach is in place to encourage the use of the CDS as an indicator of the credit quality of the counterparty and not its grade (investment or not) as followed by the new Basel regulations
Espinoza, Enrique. "Understanding help-seeking behavior among at-risk Latino male high school students". Thesis, California State University, Long Beach, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=1591627.
Texto completoThe purpose of this qualitative study was to understand the internal and external influences on help-seeking behavior in Latino male high school students (n=22) who were academically at-risk. Participants were asked to describe how and why they sought assistance from school counselors for academic and personal concerns. The data were analyzed using interpretive phenomenological analysis. The findings indicated various cultural and societal factors (gender roles, masculinity/machismo, face, and teachers of masculinity) that negatively influence help-seeking habits, while internal factors (positive internal strength, perceived knowledge and competence, and trusting relationships) were identified as positive influencers. These influencers related to one another and their relationship is drawn out in a model that described the experience of participants. Recommendations for future research and practice are provided for scholars and school personnel who work with this population.
Alrayani, H. H. A. "Understanding the biomechanical risk factors of patellofemoral pain (PFP) in military individuals". Thesis, University of Salford, 2018. http://usir.salford.ac.uk/48203/.
Texto completoRuszczyk, Hanna Alina. "The everyday and events : understanding risk perceptions and resilience in urban Nepal". Thesis, Durham University, 2017. http://etheses.dur.ac.uk/12440/.
Texto completoSundrani, Aamir (Aamir Sultan). "Understanding social amplification of risk : possible impact of an avian flu pandemic". Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/39680.
Texto completoIncludes bibliographical references (p. 71-75).
Today, stakeholders expect organizations to be able to endure external shocks. Hence, the real potential of an avian flu pandemic has many corporations developing business continuity plans for the disruptions that a pandemic may cause. For the pharmaceutical/biotechnology industry, the major concerns of a pandemic include high employee absentee rates, lack of accessibility to the medical facilities, and disruption to the product supply chain. This work introduces social amplification of risk theory to evaluate the potential impact of a pandemic to a business due to heightened fear. It uses a case study of Genzyme Corporation and evaluates pandemic related risks to two of its major products. By applying a system dynamics framework to evaluate the mechanisms for the amplification of risks, a solution is proposed. The lessons introduced in this work can help organizations evaluate the true risks of catastrophic events.
by Aamir Sundrani.
S.M.
M.B.A.