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1

Kreiman, Jody, Brian Gabelman, and Bruce R. Gerratt. "Perception of Vocal Tremor." Journal of Speech, Language, and Hearing Research 46, no. 1 (February 2003): 203–14. http://dx.doi.org/10.1044/1092-4388(2003/016).

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Vocal tremors characterize many pathological voices, but acoustic-perceptual aspects of tremor are poorly understood. To investigate this relationship, 2 tremor models were implemented in a custom voice synthesizer. The first modulated fundamental frequency (F0) with a sine wave. The second provided irregular modulation. Control parameters in both models were the frequency and amplitude of the F0 modulating waveform. Thirty-two 1-s samples of /a/, produced by speakers with vocal pathology, were modeled in the synthesizer. Synthetic copies of each vowel were created by using tremor parameters d
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2

Sabah najim, Nawras, Abdulnasir H. Ameer, and Azad A. Mohammed. "The Electrophysiological Perspectives of Essential, Enhanced Physiological, and Physiological Tremors." Journal of the Faculty of Medicine Baghdad 64, no. 2 (July 24, 2022): 86–90. http://dx.doi.org/10.32007/jfacmedbagdad.6421921.

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Abstract: Background: The most frequent movement issue seen in clinical practice is tremors. It is known as repetitive, involuntary oscillations. The diagnostic process for tremor patients can be time-consuming and complicated, as the identification of “Essential Tremor” and its distinction from other types of tremor. Objectives: This study aimed to describe the electrophysiological findings of essential, enhanced physiological, and physiological tremors, using surface electromyography and an accelerometer. Patients and Methods: The study included 24 patients with essential tremors, 10 patient
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3

Samotus, Olivia, Jack Lee, and Mandar Jog. "Developing a Consistent, Reproducible Botulinum Toxin Type A Dosing Method for Upper Limb Tremor by Kinematic Analysis." Toxins 13, no. 4 (April 8, 2021): 264. http://dx.doi.org/10.3390/toxins13040264.

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Botulinum toxin type A (BoNT-A) injection patterns customized to each patient’s unique tremor characteristics produce better efficacy and lower adverse effects compared to the fixed-muscle-fixed-dose approach for Essential Tremor (ET) and Parkinson’s disease (PD) tremor therapy. This article outlined how a kinematic-based dosing method to standardize and customize BoNT-A injections for tremors was developed. Seven ET and eight PD participants with significant tremor reduction and minimal perceived weakness using optimized BoNT-A injections determined by clinical and kinematic guidance were ret
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4

HEO, JAE-HOON, HYEONG-MIN JEON, EUI-BUM CHOI, DO-YOUNG KWON, and GWANG-MOON EOM. "EFFECT OF SENSORY ELECTRICAL STIMULATION ON RESTING TREMORS IN PATIENTS WITH PARKINSON’S DISEASE AND SWEDDs." Journal of Mechanics in Medicine and Biology 19, no. 07 (November 2019): 1940033. http://dx.doi.org/10.1142/s0219519419400335.

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Patients with scans without evidence of dopaminergic deficits (SWEDDs) show symptoms (e.g., tremors) similar to those of Parkinson’s disease (PD) patients, so they are often misdiagnosed. Sensory electrical stimulation (SES) was reported to suppress essential tremor in patients, but SES was never applied to patients with PD and SWEDDs. As the pathophysiological mechanisms of PD and SWEDDs are likely to be different, we hypothesized that the effect of SES would also be different in the two patient groups. This study aimed to test that hypothesis. Fourteen patients with PD and nine with SWEDDs p
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5

Dirkx, Michiel F., Heidemarie Zach, Bastiaan R. Bloem, Mark Hallett, and Rick C. Helmich. "The nature of postural tremor in Parkinson disease." Neurology 90, no. 13 (February 23, 2018): e1095-e1103. http://dx.doi.org/10.1212/wnl.0000000000005215.

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ObjectiveTo disentangle the different forms of postural tremors in Parkinson disease (PD).MethodsIn this combined observational and intervention study, we measured resting and postural tremor characteristics in 73 patients with tremulous PD by using EMG of forearm muscles. Patients were measured both “off” medication (overnight withdrawal) and after dispersible levodopa-benserazide 200/50 mg. We performed an automated 2-step cluster analysis on 3 postural tremor characteristics: the frequency difference with resting tremor, the degree of tremor suppression after posturing, and the dopamine res
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6

Milanov, Ivan. "Clinical and Electromyographic Examinations of Patients with Essential Tremor." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 27, no. 1 (February 2000): 65–70. http://dx.doi.org/10.1017/s0317167100052008.

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ABSTRACT:Background:It is believed that no clinical differences exist among essential, familial and senile tremor, or between the tremor with synchronous or alternating electromyographic activity. The aim of this study was to evaluate the clinical and electromyographic findings in a large group of patients with different types of essential tremor.Methods:Two hundred and twenty patients with sporadic, familial or senile variants of essential tremor were examined. According to the electromyographic activity recorded from the antagonistic muscles, the patients were subdivided into a group with sy
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7

Kim, Jeonghee, Thomas Wichmann, Omer T. Inan, and Stephen P. DeWeerth. "Analyzing the Effects of Parameters for Tremor Modulation via Phase-Locked Electrical Stimulation on a Peripheral Nerve." Journal of Personalized Medicine 12, no. 1 (January 8, 2022): 76. http://dx.doi.org/10.3390/jpm12010076.

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(1) Background: Non-invasive neuromodulation is a promising alternative to medication or deep-brain stimulation treatment for Parkinson’s Disease or essential tremor. In previous work, we developed and tested a wearable system that modulates tremor via the non-invasive, electrical stimulation of peripheral nerves. In this article, we examine the proper range and the effects of various stimulation parameters for phase-locked stimulation. (2) Methods: We recruited nine participants with essential tremor. The subjects performed a bean-transfer task that mimics an eating activity to elicit kinetic
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8

Berbakov, Lazar, Čarna Jovanović, Marina Svetel, Jelena Vasiljević, Goran Dimić, and Nenad Radulović. "Quantitative Assessment of Head Tremor in Patients with Essential Tremor and Cervical Dystonia by Using Inertial Sensors." Sensors 19, no. 19 (September 30, 2019): 4246. http://dx.doi.org/10.3390/s19194246.

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Tremor is most common among the movement disabilities that affect older people, having a prevalence rate of 4.6% in the population older than 65 years. Despite this, distinguishing different types of tremors is clinically challenging, often leading to misdiagnosis. However, due to advances in microelectronics and wireless communication, it is now possible to easily monitor tremor in hospitals and even in home environments. In this paper, we propose an architecture of a system for remote health-care and one possible implementation of such system focused on head tremor monitoring. In particular,
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9

Cichaczewski, Ederson, Renato P. Munhoz, Joaquim M. Maia, Percy Nohama, Edison M. Nóvak, and Helio A. Teive. "Electrophysiologic characteristics of tremor in Parkinson?s disease and essential tremor." Arquivos de Neuro-Psiquiatria 72, no. 4 (April 2014): 301–6. http://dx.doi.org/10.1590/0004-282x20140006.

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Tremor in essential tremor (ET) and Parkinson’s disease (PD) usually present specific electrophysiologic profiles, however amplitude and frequency may have wide variations. Objective: To present the electrophysiologic findings in PD and ET. Method: Patients were assessed at rest, with posture and action. Seventeen patients with ET and 62 with PD were included. PD cases were clustered into three groups: predominant rest tremor; tremor with similar intensity at rest, posture and during kinetic task; and predominant kinetic tremor. Results: Patients with PD presented tremors with average frequenc
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10

Mostile, Giovanni, Robert Fekete, Joseph P. Giuffrida, Toby Yaltho, Anthony Davidson, Alessandra Nicoletti, Mario Zappia, and Joseph Jankovic. "Amplitude fluctuations in essential tremor." Parkinsonism & Related Disorders 18, no. 7 (August 2012): 859–63. http://dx.doi.org/10.1016/j.parkreldis.2012.04.019.

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11

Röösli, Claudia, Fabian Walter, Stephan Husen, Lauren C. Andrews, Martin P. Lüthi, Ginny A. Catania, and Edi Kissling. "Sustained seismic tremors and icequakes detected in the ablation zone of the Greenland ice sheet." Journal of Glaciology 60, no. 221 (2014): 563–75. http://dx.doi.org/10.3189/2014jog13j210.

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AbstractDuring summer 2011, seismic activity in the ablation zone of the western Greenland ice sheet (GrIS) was monitored using a network of three-component seismometers. The seismic record includes a large variety of icequakes and seismic tremors that demonstrate a clear correlation with subglacial water flow. We verified the existence of well-known shallow icequakes (related to surface crevasse formation), deep icequakes (located at 100–160 m depth) and narrow-banded short-term seismic tremors (tens of seconds in duration). In addition, we present previously unreported long-term tremors last
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12

Smeja, M., F. Foerster, G. Fuchs, D. Emmans, A. Hornig, and J. Fahrenberg. "24-h Assessment of Tremor Activity and Posture in Parkinson's Disease by Multi-Channel Accelerometry." Journal of Psychophysiology 13, no. 4 (October 1999): 245–56. http://dx.doi.org/10.1027//0269-8803.13.4.245.

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Abstract This study describes a new method, based on accelerometry, which quantifies tremor activity and posture continuously. A total of 25 right-handed patients with Parkinson's disease were recorded in a rest condition and in a postural tremor test, and during 24-h ambulatory monitoring. The tremor parameters, such as amplitude, frequency, and occurrence (percent of time), were derived by joint amplitude-frequency analysis. The DC components of multi-channel accelerometry allowed the detection of posture. A repeated measurement MANOVA was used to test the effects of posture and night-day di
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13

Mitsui, Yuichi, Thi Thi Zin, Nobuyuki Ishii, and Hitoshi Mochizuki. "Imaging Tremor Quantification for Neurological Disease Diagnosis." Sensors 20, no. 22 (November 22, 2020): 6684. http://dx.doi.org/10.3390/s20226684.

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In this paper, we introduce a simple method based on image analysis and deep learning that can be used in the objective assessment and measurement of tremors. A tremor is a neurological disorder that causes involuntary and rhythmic movements in a human body part or parts. There are many types of tremors, depending on their amplitude and frequency type. Appropriate treatment is only possible when there is an accurate diagnosis. Thus, a need exists for a technique to analyze tremors. In this paper, we propose a hybrid approach using imaging technology and machine learning techniques for quantifi
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14

Makhoul, Karim, Rechdi Ahdab, Naji Riachi, Moussa A. Chalah, and Samar S. Ayache. "Tremor in Multiple Sclerosis—An Overview and Future Perspectives." Brain Sciences 10, no. 10 (October 12, 2020): 722. http://dx.doi.org/10.3390/brainsci10100722.

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Tremor is an important and common symptom in patients with multiple sclerosis (MS). It constituted one of the three core features of MS triad described by Charcot in the last century. Tremor could have a drastic impact on patients’ quality of life. This paper provides an overview of tremor in MS and future perspectives with a particular emphasis on its epidemiology (prevalence: 25–58%), clinical characteristics (i.e., large amplitude 2.5–7 Hz predominantly postural or intention tremor vs. exaggerated physiological tremor vs. pseudo-rhythmic activity arising from cerebellar dysfunction vs. psyc
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15

Feys, Peter, Werner Helsen, Stephan Ilsbroukx, and Tom Meurrens. "Is MS Intention Tremor Amplitude Related to Changed Peripheral Reflexes?" ISRN Neurology 2011 (September 26, 2011): 1–7. http://dx.doi.org/10.5402/2011/192414.

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Intention tremor is related to lesions in the cerebellum or connected pathways. Intention tremor amplitude decreased after peripheral arm cooling in patients with multiple sclerosis (MS), likely caused by a reduction of muscle spindle afferent inflow, while amplitude increased when muscle spindles were artificially stimulated by tendon vibration. This study investigated the contribution of peripheral reflexes to the generation of MS intention tremor. Tendon reflexes of biceps, triceps, and brachioradialis, muscles were measured, using an electromechanical triggered reflex hammer. MS patients w
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16

HEO, JAE-HOON, HYEONG-MIN JEON, EUI-BUM CHOI, DO-YOUNG KWON, and GWANG-MOON EOM. "CONTINUOUS SENSORY ELECTRICAL STIMULATION FOR THE SUPPRESSION OF PARKINSONIAN REST TREMOR." Journal of Mechanics in Medicine and Biology 18, no. 07 (November 2018): 1840006. http://dx.doi.org/10.1142/s0219519418400067.

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This paper aims to investigate the effect of continuous sensory electrical stimulation (SES) on the suppression of a Parkinsonian rest tremor. Fourteen patients with Parkinson’s disease participated in this study. Three wrist muscles were electrically stimulated on sensory level under motor threshold. Intensity of stimulation was determined for each muscle of each patient as the maximum tolerable current amplitude that does not induce muscle contraction. Tri-axial gyro sensors were attached to three upper limb segments. The angular velocity of each segment was measured for each of the three se
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17

Amarantini, David, Isabelle Rieu, Giovanni Castelnovo, Frédérique Fluchère, Chloé Laurencin, Bertrand Degos, Aurélia Poujois, et al. "Quantification of Head Tremors in Medical Conditions: A Comparison of Analyses Using a 2D Video Camera and a 3D Wireless Inertial Motion Unit." Sensors 22, no. 6 (March 19, 2022): 2385. http://dx.doi.org/10.3390/s22062385.

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This study compares two methods to quantify the amplitude and frequency of head movements in patients with head tremor: one based on video-based motion analysis, and the other using a miniature wireless inertial magnetic motion unit (IMMU). Concomitant with the clinical assessment of head tremor severity, head linear displacements in the frontal plane and head angular displacements in three dimensions were obtained simultaneously in forty-nine patients using one video camera and an IMMU in three experimental conditions while sitting (at rest, counting backward, and with arms extended). Head tr
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18

Sandström, Linda, Patric Blomstedt, Fredrik Karlsson, and Lena Hartelius. "The Effects of Deep Brain Stimulation on Speech Intelligibility in Persons With Essential Tremor." Journal of Speech, Language, and Hearing Research 63, no. 2 (February 26, 2020): 456–71. http://dx.doi.org/10.1044/2019_jslhr-19-00014.

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Purpose The aim of this study was to investigate how deep brain stimulation (DBS) of the caudal zona incerta (cZi) affects speech intelligibility in persons with essential tremor. Method Thirty-five participants were evaluated: off stimulation, on chronic stimulation optimized to alleviate tremor, and during unilateral stimulation at increasing amplitude levels. At each stimulation condition, the participants read 10 unique nonsense sentences from the Swedish Test of Intelligibility. Two listeners, blinded to stimulation condition, transcribed all recorded sentences orthographically in a rando
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19

Paschal, O’Gorman, Williams Stefan, Fang Hui, Qahwaji Rami, Patel Parisa, Graham Christopher D, and Alty Jane. "WED 112 Seeing invisible parkinsonian tremor with a smartphone camera." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 10 (September 13, 2018): A12.1—A12. http://dx.doi.org/10.1136/jnnp-2018-abn.43.

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Arthur C Clarke’s ‘third law’ states that any sufficiently advanced technology is indistinguishable from magic. Computer vision is the processing of images or video by computer to extract useful information. A technique termed ‘Eulerian magnification’ involves amplification of tiny movements from video recordings, so that very small motions can become visible to the human eye. This has the potential to detect tremor that is of such small amplitude it cannot otherwise be seen. Crucially, the only hardware required is a camera and computer processor, items that are ubiquitous. There is only one
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20

McCarroll, R. S., and J. H. De Vries. "The Influence of Tonic Muscle Activation on Human Jaw Displacement Tremor." Journal of Dental Research 67, no. 8 (August 1988): 1081–85. http://dx.doi.org/10.1177/00220345880670080401.

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Jaw displacement tremor was investigated. Both tremor amplitude and tremor frequency were found to increase with increasing muscle activation. Co-contraction of jaw elevator and jaw depressor muscles was employed in order to vary muscle activation levels without the teeth being in occlusion. Reproducibility of tremor changes was statistically significant for each individual investigated. The relationship between tremor frequency and tremor amplitude, over the range of muscle activation investigated, varied per individual. It is hypothesized that the physiological basis for this inter-individua
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21

Iizuka, T., A. Takeuchi, M. Shirataka, N. Ikeda, and N. Mamorita. "Development of a System for Measurement and Analysis of Tremor Using a Three-axis Accelerometer." Methods of Information in Medicine 48, no. 06 (2009): 589–94. http://dx.doi.org/10.3414/me9243.

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Summary Objectives: The aim of the study was to develop a low-cost and compact system for analysis of tremor using a three-axis accelerometer (the Wii Remote (Nintendo)). To analyze tremor, we hypothesized that the influence of gravitational acceleration should be separated from that of movement. This hypothesis was tested experimentally and we also attempted to record and analyze tremor using our system in a clinical ward. Methods: A system for tremor measurement and analysis was developed using the three-axis accelerometer built into the Wii Remote. The frequency and amplitude of mechanical
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22

Winholtz, William S., and Lorraine Olson Ramig. "Vocal Tremor Analysis With the Vocal Demodulator." Journal of Speech, Language, and Hearing Research 35, no. 3 (June 1992): 562–73. http://dx.doi.org/10.1044/jshr.3503.562.

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Acoustic analysis of vocal tremor has the potential to make significant quantitative and diagnostic contributions to the study of vocal disorders. This paper presents a new device for analysis of vocal tremor. The Vocal Demodulator produces amplitude- and frequency-demodulated outputs and measures the frequency and level (percent) of low-frequency tremor components in sustained phonation. A standard microphone is used to transduce the voice signal for input to the demodulator. The input fundamental frequency (F o ) range is 70–1200 Hz, and frequency response of the amplitude and frequency demo
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23

de Faria, Stephanie Martins, Daiene de Morais Fabrício, Vitor Tumas, Paula Costa Castro, Moacir Antonelli Ponti, Jaime EC Hallak, Antonio W. Zuardi, José Alexandre S. Crippa, and Marcos Hortes Nisihara Chagas. "Effects of acute cannabidiol administration on anxiety and tremors induced by a Simulated Public Speaking Test in patients with Parkinson’s disease." Journal of Psychopharmacology 34, no. 2 (January 7, 2020): 189–96. http://dx.doi.org/10.1177/0269881119895536.

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Background: Cannabidiol (CBD) is one of the main components of Cannabis sativa and has anxiolytic properties, but no study has been conducted to evaluate the effects of CBD on anxiety signs and symptoms in patients with Parkinson’s disease (PD). This study aimed to evaluate the impacts of acute CBD administration at a dose of 300 mg on anxiety measures and tremors induced by a Simulated Public Speaking Test (SPST) in individuals with PD. Methods: A randomised, double-blinded, placebo-controlled, crossover clinical trial was conducted. A total of 24 individuals with PD were included and underwe
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24

Jensen, Lauren, Michael Dancisak, and James Korndorffer. "Muscle-Cooling Intervention to Reduce Fatigue and Fatigue-Induced Tremor in Novice and Experienced Surgeons: A Preliminary Investigation." Surgery Journal 02, no. 04 (October 2016): e126-e130. http://dx.doi.org/10.1055/s-0036-1594246.

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AbstractA localized, intermittent muscle-cooling protocol was implemented to determine cooling garment efficacy in reducing upper extremity muscular fatigue and tremor in novice (n = 10) and experienced surgeons (n = 9). Subjects wore a muscle-cooling garment while performing multiple trials of a forearm exercise and paired suturing task to induce muscular fatigue and exercise-induced tremor. A reduction in tremor amplitude and an extension in time to fatigue were expected with muscle cooling as compared with control trials. Each subject completed an intervention session (5°C cooling condition
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25

Aronson, Arnold E., William S. Winholtz, Lorraine Olson Ramig, and Sandra R. Silber. "Rapid Voice Tremor, or “Flutter,” in Amyotrophic Lateral Sclerosis." Annals of Otology, Rhinology & Laryngology 101, no. 6 (June 1992): 511–18. http://dx.doi.org/10.1177/000348949210100612.

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In an attempt to clarify the origin and frequency characteristics of a rapid voice tremor, or “flutter,” in patients with amyotrophic lateral sclerosis (ALS), eight patients (four men and four women; ages 42 to 70 years) who had ALS and rapid voice tremor and an age-and sex-matched control group of eight subjects were asked to sustain the vowel /a/ and their voices were recorded for later analysis. Each segment of phonation was demodulated into amplitude and frequency components. From each subject's 8-second amplitude and frequency signals, a fast Fourier transform analysis was done on a 1-sec
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26

Cagnan, Hayriye, John-Stuart Brittain, Simon Little, Thomas Foltynie, Patricia Limousin, Ludvic Zrinzo, Marwan Hariz, et al. "Phase dependent modulation of tremor amplitude in essential tremor through thalamic stimulation." Brain 136, no. 10 (October 2013): 3062–75. http://dx.doi.org/10.1093/brain/awt239.

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27

Moyer, Paula. "TREMOR RATING SCALE CAN ASSESS AMPLITUDE OF ESSENTIAL TREMOR, RESPONSE TO TREATMENT." Neurology Today 4, no. 10 (October 2004): 63. http://dx.doi.org/10.1097/00132985-200410000-00015.

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28

Moyer, Paula. "TREMOR RATING SCALE CAN ASSESS AMPLITUDE OF ESSENTIAL TREMOR, RESPONSE TO TREATMENT." Neurology Today 4, no. 10 (October 2004): 63,64. http://dx.doi.org/10.1097/00132985-200410000-00019.

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29

Cleeves, L., and L. J. Findley. "Variability in amplitude of untreated essential tremor." Journal of Neurology, Neurosurgery & Psychiatry 50, no. 6 (June 1, 1987): 704–8. http://dx.doi.org/10.1136/jnnp.50.6.704.

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30

Dirkx, Michiel F., Heidemarie Zach, Annelies J. van Nuland, Bastiaan R. Bloem, Ivan Toni, and Rick C. Helmich. "Cognitive load amplifies Parkinson’s tremor through excitatory network influences onto the thalamus." Brain 143, no. 5 (May 1, 2020): 1498–511. http://dx.doi.org/10.1093/brain/awaa083.

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Abstract Parkinson’s tremor is related to cerebral activity in both the basal ganglia and a cerebello-thalamo-cortical circuit. It is a common clinical observation that tremor markedly increases during cognitive load (such as mental arithmetic), leading to serious disability. Previous research has shown that this tremor amplification is associated with reduced efficacy of dopaminergic treatment. Understanding the mechanisms of tremor amplification and its relation to catecholamines might help to better control this symptom with a targeted therapy. We reasoned that, during cognitive load, tremo
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31

Sturman, Molly M., David E. Vaillancourt, and Daniel M. Corcos. "Effects of Aging on the Regularity of Physiological Tremor." Journal of Neurophysiology 93, no. 6 (June 2005): 3064–74. http://dx.doi.org/10.1152/jn.01218.2004.

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The purpose of this investigation was to determine the effects of healthy aging on the regularity of physiological tremor under rest and postural conditions. Additionally, we examined the contribution of mechanical reflex factors to age-related changes in postural physiological tremor. Tremor regularity, tremor–electromyographic (EMG) coherence, tremor amplitude, and tremor modal frequency were calculated for 4 age groups (young: 20–30 yr, young-old: 60–69 yr, old: 70–79 yr, and old-old: 80–94 yr) under resting and loaded postural conditions. There were 6 important findings from this study: 1)
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32

Krauss, Joachim K., Mohsen Mohadjer, Fritz Nobbe, and Fritz Mundinger. "The treatment of posttraumatic tremor by stereotactic surgery." Journal of Neurosurgery 80, no. 5 (May 1994): 810–19. http://dx.doi.org/10.3171/jns.1994.80.5.0810.

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✓ The authors report the long-term results of stereotactic surgery for severe posttraumatic appendicular tremor in 35 patients. The tremors developed after severe head trauma in 33 patients (94%) and after mild to moderate head trauma in two (6%). In all but one, the tremor was most evident during activity. The amplitude of the kinetic tremor was greater than 5 cm in 33 patients (94%) and greater than 12 cm in 19 patients (54%). All were severely incapacitated in their daily living activities due to the tremors. The 35 patients underwent 42 stereotactic operations; five patients were reoperate
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33

Shah, A., J. Coste, JJ Lemaire, E. Schkommodau, and S. Hemm-Ode. "Use of quantitative tremor evaluation to enhance target selection during deep brain stimulation surgery for essential tremor." Current Directions in Biomedical Engineering 1, no. 1 (September 1, 2015): 488–92. http://dx.doi.org/10.1515/cdbme-2015-0117.

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AbstractDeep brain stimulation (DBS), an effective surgical treatment for Essential Tremor (ET), requires test stimulations in the thalamus to find the optimum site for permanent electrode implantation. During these test stimulations, the changes in tremor are only visually evaluated. This, along with other parameters, increases the subjectivity when comparing the efficacy of different thalamic nuclei. We developed a method to quantitatively evaluate tremor during the test stimulations of DBS surgery and applied to 6 ET patients undergoing this treatment. From the quantitative data collected,
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34

Elble, R. J. "Tremor amplitude is logarithmically related to 4- and 5-point tremor rating scales." Brain 129, no. 10 (July 15, 2006): 2660–66. http://dx.doi.org/10.1093/brain/awl190.

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35

Habib, Md Ahsan, ASM Alamgir, Subash Kanti Dey, Afroja Alam, Ahmed Asafuddoula, and Abu Nasir Rizvi. "Effect of Trihexiphenidyl and Procyclidine for the management of resting tremor." Bangladesh Medical Journal 44, no. 2 (April 5, 2016): 72–75. http://dx.doi.org/10.3329/bmj.v44i2.27241.

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Parkinson’s disease is the main etiology of resting tremor but may also rarely occur in Essential Tremor, Multiple System Atrophy & Progressive Suprneuclear Palsy. Levodopa improves bradykinesia, rigidity and other commonly associated symptoms. When resting tremor is the predominant presenting symptom of Parkinson's disease or when tremor persists despite adequate control of other parkinsonian symptoms with low dosages of levodopa, an anticholinergic agent such as trihexyphenidyl or Procyclidine may be the treatment of choice. This prospective interventional study was carried out in the de
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36

Essing, David, Vera Schlindwein, Mechita C. Schmidt-Aursch, Celine Hadziioannou, and Simon C. Stähler. "Characteristics of Current-Induced Harmonic Tremor Signals in Ocean-Bottom Seismometer Records." Seismological Research Letters 92, no. 5 (April 28, 2021): 3100–3112. http://dx.doi.org/10.1785/0220200397.

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Abstract Long-lasting harmonic tremor signals are frequently observed in spectrograms of seismological data. Natural sources, such as volcanoes and icebergs, or artificial sources, such as ships and helicopters, produce very similar harmonic tremor episodes. Ocean-bottom seismometer (OBS) records may additionally be contaminated by tremor induced by ocean-bottom currents acting on the OBS structure. This harmonic tremor noise may severely hinder earthquake detection and can be misinterpreted as volcanic tremor. In a 160-km-long network of 27 OBSs deployed for 1 yr along the Knipovich ridge in
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37

Muruzheva, Zamira M., Aleksey A. Ezhov, Marina N. Karpenko, Marina A. Fominceva, Victor M. Klimenko, and Igor D. Stolyarov. "Clinical and electrophysiological heterogeneity of essential tremor." Medical academic journal 18, no. 4 (December 15, 2018): 64–72. http://dx.doi.org/10.17816/maj18464-72.

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This study aimed to identify clinical and electrophysiological signs that determine the phenotypic heterogeneity of essential tremor using a cluster analysis. Seventy-five patients with essential tremor were examined. To identify the heterogeneity of the disease, a cluster analysis was applied (k-means method). Clustering was performed according to clinical and electromyographic parameters. The heterogeneity of essential tremor is justified by amplitude characteristics, topography of tremor, duration disease, and severity of impaired of daily activity. Detecting heterogeneity in essential trem
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38

Carbonell, Kathy M., Brad Story, Rosemary Lester, and Andrew J. Lotto. "Discriminating vocal tremor source from amplitude envelope modulations." Journal of the Acoustical Society of America 132, no. 3 (September 2012): 2090. http://dx.doi.org/10.1121/1.4755723.

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39

Aleksandrov, A. Yu, K. O. Uplisova, and V. Yu Ivanova. "Biofeedback Specialization Effect on Physiological Tremor Amplitude Dynamics." Human Physiology 46, no. 2 (March 2020): 127–33. http://dx.doi.org/10.1134/s036211972001003x.

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40

Slack, Paul S., and Xianghong Ma. "Tremor amplitude determination for use in clinical applications." Measurement Science and Technology 18, no. 11 (October 4, 2007): 3471–78. http://dx.doi.org/10.1088/0957-0233/18/11/030.

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41

Akyürekli, Onder, Çağla Kaya, Fisun Ersan, and Acarer Ahmet. "WO23 Does tremor amplitude depend on receptor subtype?" Clinical Neurophysiology 119 (May 2008): S26. http://dx.doi.org/10.1016/s1388-2457(08)60103-0.

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42

Rahimi, Fariborz, Derek Debicki, Angela Roberts-South, Carina Bee, Priya Bapat, and Mandar Jog. "Dynamic Decomposition of Motion in Essential and Parkinsonian Tremor." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 42, no. 2 (February 23, 2015): 116–24. http://dx.doi.org/10.1017/cjn.2015.12.

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AbstractBackground: Treatment options for essential (ET) and Parkinson disease (PD) tremor are suboptimal, with significant side effects. Botulinum toxin type A (BoNT A) is successfully used in management of various focal movement disorders but is not widely used for tremor. Method: This study examines complexity of wrist tremor in terms of involvement of its three anatomical degrees of freedom (DOF) in two common situations of rest and posture. The study examines tremor in 11 ET and 17 PD participants by kinematic decomposition of motion in 3-DOF. Results: Tremor decomposition showed the moti
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43

Fekete, Robert. "Paroxysmal Nonkinesigenic Dyskinesia with Tremor." Case Reports in Neurological Medicine 2013 (2013): 1–2. http://dx.doi.org/10.1155/2013/927587.

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Introduction. Paroxysmal nonkinesigenic dyskinesia (PNKD) consists of episodes of chorea, athetosis, or dystonia which are not triggered by movement, with complete remission between episodes. A case of genetically confirmed PNKD with simultaneous tremor has not been previously reported.Case Report. The patient is an 86-year-old right-handed female who presented with episodic stiffness, with onset at age 9. Attacks have a prodrome of difficulty in speaking, followed by abnormal sensation in extremities. Episodes consist of dystonia of trunk associated with upper and lower extremity chorea. Ther
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Rajput, Ali H., and Alex Rajput. "Medical Treatment of Essential Tremor." Journal of Central Nervous System Disease 6 (January 2014): JCNSD.S13570. http://dx.doi.org/10.4137/jcnsd.s13570.

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Essential tremor (ET) is the most common pathological tremor characterized by upper limb action—postural tremor (PT)/kinetic tremor (KT). There are no specific neuropathological or biochemical abnormalities in ET. The disability is consequent to amplitude of KT, which may remain mild without handicap or may become disabling. The most effective drugs for sustained tremor control are propranolol and primidone. Symptomatic drug treatment must be individualized depending on the circumstances that provoke the tremor-related disability. Broad guidelines for treatment are discussed in this review. Pa
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45

Samotus, Olivia, Jack Lee, and Mandar Jog. "Standardized algorithm for muscle selection and dosing of botulinum toxin for Parkinson tremor using kinematic analysis." Therapeutic Advances in Neurological Disorders 13 (January 2020): 175628642095408. http://dx.doi.org/10.1177/1756286420954083.

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Background: Inadequate efficacy and significant side effect profile makes pharmacological treatment of Parkinson’s disease (PD) tremor challenging. Personalized dosing of botulinum toxin type A (BoNT-A) using tremor analysis has shown efficacy and safety for treating upper limb tremor. This study incorporated a novel, standardized treatment algorithm for determining injection pattern and BoNT-A dosing, customizable by the physician, in PD patients with disabling tremor in one or both arms. Methods: This open-label study included 47 PD participants (25 “De-novo” and 22 “L-dopa”) who received 4
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46

Walsh, Bridget, and Anne Smith. "Oral Electromyography Activation Patterns for Speech Are Similar in Preschoolers Who Do and Do Not Stutter." Journal of Speech, Language, and Hearing Research 56, no. 5 (October 2013): 1441–54. http://dx.doi.org/10.1044/1092-4388(2013/12-0177).

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Purpose In this study, the authors determined whether basic patterns of muscle activation for speech were similar in preschool children who stutter and in their fluent peers. Method Right and left lower lip muscle activity were recorded during conversational speech and sentence repetition in 64 preschool children diagnosed as stuttering (CWS) and in 40 children who do not stutter (CWNS). Measures of electromyography (EMG) amplitude, right–left asymmetry, and bilateral coordination were computed for fluent speech. The potential presence of tremor-like oscillations during disfluencies of CWS was
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47

Keogh, Justin W. L., Steve Morrison, and Rod Barrett. "Strength and Coordination Training Are Both Effective in Reducing the Postural Tremor Amplitude of Older Adults." Journal of Aging and Physical Activity 18, no. 1 (January 2010): 43–60. http://dx.doi.org/10.1123/japa.18.1.43.

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The current study investigated the effect of 2 different types of unilateral resistance training on the postural tremor output of 19 neurologically healthy men age 70–80 yr. The strength- (n= 7) and coordination-training (n= 7) groups trained twice a week for 6 wk, performing dumbbell biceps curls, wrist flexions, and wrist extensions, while the control group (n= 5) maintained their normal activities. Changes in index-finger tremor (RMS amplitude, peak, and proportional power) and upper limb muscle coactivation were assessed during 4 postural conditions that were performed separately with the
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48

Hopfner, Franziska, Tatjana Erhart, Karina Knudsen, Delia Lorenz, Susanne A. Schneider, Kirsten E. Zeuner, Günther Deuschl, and Gregor Kuhlenbäumer. "Testing for alcohol sensitivity of tremor amplitude in a large cohort with essential tremor." Parkinsonism & Related Disorders 21, no. 8 (August 2015): 848–51. http://dx.doi.org/10.1016/j.parkreldis.2015.05.005.

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49

Park, Kye Won, Eun-Jae Lee, Jun Seong Lee, Jinhoon Jeong, Nari Choi, Sungyang Jo, Mina Jung, et al. "Machine Learning–Based Automatic Rating for Cardinal Symptoms of Parkinson Disease." Neurology 96, no. 13 (February 10, 2021): e1761-e1769. http://dx.doi.org/10.1212/wnl.0000000000011654.

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ObjectiveWe developed and investigated the feasibility of a machine learning–based automated rating for the 2 cardinal symptoms of Parkinson disease (PD): resting tremor and bradykinesia.MethodsUsing OpenPose, a deep learning–based human pose estimation program, we analyzed video clips for resting tremor and finger tapping of the bilateral upper limbs of 55 patients with PD (110 arms). Key motion parameters, including resting tremor amplitude and finger tapping speed, amplitude, and fatigue, were extracted to develop a machine learning–based automatic Unified Parkinson's Disease Rating Scale (
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50

Güney, Gökhan, Talisa S. Jansen, Sebastian Dill, Jörg B. Schulz, Manuel Dafotakis, Christoph Hoog Antink, and Anne K. Braczynski. "Video-Based Hand Movement Analysis of Parkinson Patients before and after Medication Using High-Frame-Rate Videos and MediaPipe." Sensors 22, no. 20 (October 20, 2022): 7992. http://dx.doi.org/10.3390/s22207992.

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Tremor is one of the common symptoms of Parkinson’s disease (PD). Thanks to the recent evolution of digital technologies, monitoring of PD patients’ hand movements employing contactless methods gained momentum. Objective: We aimed to quantitatively assess hand movements in patients suffering from PD using the artificial intelligence (AI)-based hand-tracking technologies of MediaPipe. Method: High-frame-rate videos and accelerometer data were recorded from 11 PD patients, two of whom showed classical Parkinsonian-type tremor. In the OFF-state and 30 Minutes after taking their standard oral medi
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