Bibliografías temáticas / Toxicology

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Literatura académica sobre el tema "Toxicology"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 30 de julio de 2024

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Artículos de revistas sobre el tema "Toxicology"

1

Hayes, A. Wallace y Darlene Dixon. "Cornerstones of Toxicology". Toxicologic Pathology 45, n.º 1 (enero de 2017): 57–63. http://dx.doi.org/10.1177/0192623316675768.

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The 35th Annual Society of Toxicologic Pathology Symposium, held in June 2016 in San Diego, California, focused on “The Basis and Relevance of Variation in Toxicologic Responses.” In order to review the basic tenants of toxicology, a “broad brush” interactive talk that gave an overview of the Cornerstones of Toxicology was presented. The presentation focused on the historical milestones and perspectives of toxicology and through many scientific graphs, data, and real-life examples covered the three basic principles of toxicology that can be summarized, as dose matters (as does timing), people differ, and things change (related to metabolism and biotransformation).
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BABIŃSKA, IZABELLA, JÓZEF SZAREK, MARIUSZ Z. FELSMANN y ANDRZEJ DZIKOWSKI. "Scientific toxicology societies in Europe". Medycyna Weterynaryjna 74, n.º 1 (2018): 5981–2018. http://dx.doi.org/10.21521/mw.5981.

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With the development of toxicology as a science, the second half of the 20th century saw the establishment of scientific societies, such as the International Society of Ecotoxicology and Environmental Safety (SECOTOX), the Federation of European Toxicologists and European Societies of Toxicology (EUROTOX), the Polish Society of Toxicology, and the European Society of Toxicologic Pathology (ESTP). This study describes their development, organizational structure and mission. The scope of their interest, in addition to toxicology, also includes ecotoxicology, which protects the natural environment and public health..
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Hukkanen, Renee R., Noel Dybdal, Niraj Tripathi, Patricia V. Turner y Sean P. Troth. "Scientific and Regulatory Policy Committee Points to Consider*: The Toxicologic Pathologist’s Role in the 3Rs". Toxicologic Pathology 47, n.º 7 (octubre de 2019): 789–98. http://dx.doi.org/10.1177/0192623319859261.

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Pathologists are trained medical professionals with special expertise in diagnostics, research, and pathophysiology. In these roles, pathologists are well qualified and positioned to engage in conversations about animal use replacement, reduction, and refinement (3Rs), thereby championing the guiding principles of the 3Rs. In particular, toxicology or nonclinical safety assessment is an important area where the discipline of toxicologic pathology can have a critical role in adopting 3Rs principles. As such, a working group of the Society of Toxicologic Pathology Scientific and Regulatory Policy Committee was formed to investigate and summarize some of the areas where veterinary pathologists working in the field of toxicology can increase involvement and impact on 3Rs. This “Points to Consider” publication provides an overview of areas within toxicology where the veterinary pathologist’s perspective may maximize animal value, including refinement of study design, optimizing sample collection, the development of 3Rs focused regulatory policy, and humane end point determination.[Box: see text]
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Cohen, Samuel M., Wanda M. Haschek-Hock y Carl Alden. "Obituary: Dr Gordon Charles Hard (1931-2021)". Toxicologic Pathology 50, n.º 2 (8 de enero de 2022): 164–65. http://dx.doi.org/10.1177/01926233211068853.

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Dr Gordon Hard, of Tairua, New Zealand, a preeminent international toxicology thought leader and international consultant in toxicologic pathology of the kidney, passed on November 22, 2021. He was a key player in shaping and developing the global field of toxicologic pathology and the role of toxicologic pathology in risk assessment of environmental chemicals and pharmaceuticals.
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Bolon (Chair), Brad, Erio Barale-Thomas, Alys Bradley, Robert A. Ettlin, Carla A. S. Franchi, Catherine George, Anna Maria Giusti et al. "International Recommendations for Training Future Toxicologic Pathologists Participating in Regulatory-type, Nonclinical Toxicity Studies". Toxicologic Pathology 38, n.º 6 (17 de agosto de 2010): 984–92. http://dx.doi.org/10.1177/0192623310378137.

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The International Federation of Societies of Toxicologic Pathologists (IFSTP) proposes a common global framework for training future toxicologic pathologists who will support regulatory-type, nonclinical toxicology studies. Optimally, trainees should undertake a scientific curriculum of at least five years at an accredited institution leading to a clinical degree (veterinary medicine or medicine). Trainees should then obtain four or more years of intensive pathology practice during a residency and/or on-the-job “apprenticeship,” at least two years of which must be focused on regulatory-type toxicologic pathology topics. Possession of a recognized pathology qualification (i.e., certification) is highly recommended. A nonclinical pathway (e.g., a graduate degree in medical biology or pathology) may be possible if medically trained pathologists are scarce, but this option is not optimal. Regular, lifelong continuing education (peer review of nonclinical studies, professional meetings, reading, short courses) will be necessary to maintain and enhance one’s understanding of current toxicologic pathology knowledge, skills, and tools. This framework should provide a rigorous yet flexible way to reliably train future toxicologic pathologists to generate, interpret, integrate, and communicate data in regulatory-type, nonclinical toxicology studies.
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Maronpot, Robert R., Abraham Nyska, Sean P. Troth, Kathleen Gabrielson, Polina Sysa-Shah, Vyacheslav Kalchenko, Yuri Kuznetsov et al. "Regulatory Forum Opinion Piece*: Imaging Applications in Toxicologic Pathology—Recommendations for Use in Regulated Nonclinical Toxicity Studies". Toxicologic Pathology 45, n.º 4 (junio de 2017): 444–71. http://dx.doi.org/10.1177/0192623317710014.

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Available imaging systems for use in preclinical toxicology studies increasingly show utility as important tools in the toxicologic pathologist’s armamentarium, permit longitudinal evaluation of functional and morphological changes in tissues, and provide important information such as organ and lesion volume not obtained by conventional toxicology study parameters. Representative examples of practical imaging applications in toxicology research and preclinical studies are presented for ultrasound, positron emission tomography/single-photon emission computed tomography, optical, magnetic resonance imaging, and matrix-assisted laser desorption ionization—imaging mass spectrometry imaging. Some of the challenges for making imaging systems good laboratory practice–compliant for regulatory submission are presented. Use of imaging data on a case-by-case basis as part of safety evaluation in regulatory submissions is encouraged.
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Troth, Sean P., Nancy E. Everds, William Siska, Brian Knight, Martin Lamb y Julie Hutt. "Scientific and Regulatory Policy Committee Points to Consider: Data Visualization for Clinical and Anatomic Pathologists". Toxicologic Pathology 46, n.º 5 (29 de mayo de 2018): 476–87. http://dx.doi.org/10.1177/0192623318778733.

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Assessment and communication of toxicology data are fundamental components of the work performed by veterinary anatomic and clinical pathologists involved in toxicology research. In recent years, there has been an evolution in the number and variety of software tools designed to facilitate the evaluation and presentation of toxicity study data. A working group of the Society of Toxicologic Pathology Scientific and Regulatory Policy Committee reviewed existing and emerging visualization technologies. This Points to Consider article reviews some of the currently available data visualization options, describes the utility of different types of graphical displays, and explores potential areas of controversy and ambiguity encountered with the use of these tools.
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Bhat, Sagar S. y Srinivasa Gopala Rao. "Toxicology-the blind spot". Asian Pacific Journal of Health Sciences 5, n.º 3 (julio de 2018): 225–32. http://dx.doi.org/10.21276/apjhs.2018.5.3.31.

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Hobson, David W., Stephen M. Roberts, Anna A. Shvedova, David B. Warheit, Georgia K. Hinkley y Robin C. Guy. "Applied Nanotoxicology". International Journal of Toxicology 35, n.º 1 (enero de 2016): 5–16. http://dx.doi.org/10.1177/1091581816628484.

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Nanomaterials, including nanoparticles and nanoobjects, are being incorporated into everyday products at an increasing rate. These products include consumer products of interest to toxicologists such as pharmaceuticals, cosmetics, food, food packaging, household products, and so on. The manufacturing of products containing or utilizing nanomaterials in their composition may also present potential toxicologic concerns in the workplace. The molecular complexity and composition of these nanomaterials are ever increasing, and the means and methods being applied to characterize and perform useful toxicologic assessments are rapidly advancing. This article includes presentations by experienced toxicologists in the nanotoxicology community who are focused on the applied aspect of the discipline toward supporting state of the art toxicologic assessments for food products and packaging, pharmaceuticals and medical devices, inhaled nanoparticle and gastrointestinal exposures, and addressing occupational safety and health issues and concerns. This symposium overview article summarizes 5 talks that were presented at the 35th Annual meeting of the American College of Toxicology on the subject of “Applied Nanotechnology.”
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Lamb, J. C., M. D. Ross y R. E. Chapin. "Experimental Methods for Studying Male Reproductive Function in Standard Toxicology Studies". Journal of the American College of Toxicology 5, n.º 4 (julio de 1986): 225–34. http://dx.doi.org/10.3109/10915818609140747.

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Indicators of insult to the male reproductive system can be incorporated into standard toxicology studies so that the assessment of reproductive toxicity does not interfere with the general toxicologic evaluation. This can include assessment of testicular spermatids, or sperm from the epididymis, or vas deferens, or assessment of semen collected from the female reproductive tract postcoitally. Endpoints evaluated may include sperm count, motility, or sperm head morphology. Testicular morphology also may be evaluated by various improved histologic techniques. For example, when testes are immersion-fixed in formalin, testicular morphology is significantly improved by embedding the tissue in the water-soluble plastic glycol methacrylate (GMA) rather than paraffin. These approaches to male reproductive toxicology are cost-effective and reduce the number of animals required for pilot or survey studies for testicular toxicity. They can provide useful data on male reproductive function.
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Tesis sobre el tema "Toxicology"

1

Malheiro, Ana Cristina Calhabeutt Gabriel da Costa. "Determinação espectrofotométrica da caboxiemoglobinemia em indivíduos expostos ocupacionalmente ao monóxido de carbono". Universidade de São Paulo, 1991. http://www.teses.usp.br/teses/disponiveis/9/9137/tde-03032015-160133/.

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O monóxido de carbono (CO) constitui sério risco à saúde de indivíduos expostos a este gás. Os efeitos nocivos aparecem como conseqüência de sua combinação com a hemoglobina formando a carboxiemoglobina(COHb). A avaliação da exposição ao CO pela monitorização biológica é realizada, preferencialmente, pela determinação da carboxiemoglobinemia. O método espectrofotométrico proposto, para a determinação de COHb, utiliza a leitura na região Soret (420 e 432 nm) e fatores de calibração do espectrofotômetro. É realizado estudo comparativo entre o uso do CO obtido por reação química e o de cilindro de gás no preparo de solução 100% de COHb. O método apresenta boa precisão (coeficiente de variação de 2 e 6% para 4,98 e 1,01 % de COHb, respectivamente) e sensibilidade (0,50 % de COHb) adequadas à avaliação da exposição ao monóxido de carbono. A quantificação da COHb não é comprometida pelo teor hemoglobínico nem pela opalescência (lipemia) da amostra colhida no período pós-prandial. É apresentada a carboxiemoglobinemia em fumantes (n= 119) e não-fumantes (n= 189) que constituem 4 grupos de indivíduos expostos ocupacionalmente ao CO (n=209) e um grupo controle (n=99); e a análise estatística dos resultados (teste não-paramétrico).
Carbon monoxide (CO) is recognized as a high risk hazard to the health of exposed workers. Combining with hemoglobin it reduces the oxigen carrying capacity of the blood. The individual overall exposure may be assessed through the carboxyhemoglobin (COHb) content of blood samples, as a biological exposure index. A spectrophotometric method is proposed using measurements in the region Soret (420 - 432 nrn) together with calibration factors of the instrument. A comparative study is made between the use of CO from compressed gas cilinders and the CO delivered by a chemical reaction in preparing the saturated COHb solution. The method presents precision (coefficient of variation is 2 and 6% to 4,98 and 1,01% of COHb, respectively) and sensitivity (0,5% of COHb), which are adequate to the purpose. Hemoglobin and lipidic content of samples showed no effect in the COHb measurement. Carboxyhiemoglobin level of four groups of exposed workers (n = 209) and a control group (n = 99) among smokers (n = 115) and non-smokers (n = 189) were determinated using the method. The statistical analysis of the results are presented (non-parametric test).
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Oliveira, Ricardo Jorge Dinis. "Toxicity of Paraquat in Isolated Rat Lung. Search for Efficient Antidotes". Doctoral thesis, Faculdade de Farmácia da Universidade do Porto, 2006. http://hdl.handle.net/10216/7369.

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The immune evasion mechanisms of pathogenic trypanosomatids involve a multitude of phenomena such as the polyclonal activation of lymphocytes, cytokine modulation and the enhanced detoxification of oxygen reactive species. A trypanothione-cascade seems to be involved in the detoxification process. We have recently described and characterized a tryparedoxin (LiTXN1) involved in the Leishmania infantum cytoplasmatic hydroperoxide metabolism. LiTXN1 is a secreted protein upregulated in the infectious form of the parasite, suggesting that it can play an important role during infection. In the present study, we investigated whether the recombinant LiTXN1 (rLiTXN1) would affect T and B cell functions in a murine model. We observed a significant increase of CD69 surface marker on the B-cell population in total spleen and on isolated B-cells from BALB/c mice after in vitro rLiTXN1 stimulus. Activated Bcells underwent further proliferation, as measured by an increased [3H]-thymidine incorporation. Cytokine quantification showed a dose-dependent upregulation of IL-10 secretion. B-cells were identified as a source. Furthermore, intraperitoneal injection of rLiTXN1 into BALB/c mice triggered the production of elevated levels of rLiTXN1 specific antibodies, predominantly of the IgM, IgG1 and IgG3 isotypes, with a minimum reactivity against other heterologous antigens. Taken together, our data suggest that rLiTXN1 could participate in the immunopathological processes by targeting the B-cells effector functions with subsequent IL-10 secretion and specific antibodies production.
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Costa, Vera Marisa Freitas. "Role of catecholamines and reactive oxygen species in the mechanism of oxidative stress-induced heart disease:in vitro studies using fresly isolated rat cardiomyocytes". Doctoral thesis, Faculdade de Farmácia da Universidade do Porto, 2008. http://hdl.handle.net/10216/20812.

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Pontes, Helena de Oliveira. "Toxicological and Toxicokinetic Interactions Between Ethanol and Ecstasy. In Vivo and In Vitro Studies". Doctoral thesis, Faculdade de Farmácia da Universidade do Porto, 2008. http://hdl.handle.net/10216/9486.

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Alves, Ema Luís Pereira Gomes. "Neurotoxicity of Methylenedioxymethamphetamine (MDMA; Ecstasy) and its Main Metabolites, on Rat Brain Mitochondria In Vitro and In Vivo - Behavioral Consequences". Doctoral thesis, Faculdade de Farmácia da Universidade do Porto, 2007. http://hdl.handle.net/10216/7499.

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Monteagudo, Maykel Cruz. "Multi-Objective Optimization Based on Desirability Estimation of Several Interrelated Responses (MOOp-DESIRe): A Computer-Aided Methodology for Multi-Criteria Drug Discovery". Doctoral thesis, Faculdade de Farmácia da Universidade do Porto, 2009. http://hdl.handle.net/10216/63799.

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Monteagudo, Maykel Cruz. "Multi-Objective Optimization Based on Desirability Estimation of Several Interrelated Responses (MOOp-DESIRe): A Computer-Aided Methodology for Multi-Criteria Drug Discovery". Tese, Faculdade de Farmácia da Universidade do Porto, 2009. http://hdl.handle.net/10216/63799.

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Alves, Ema Luís Pereira Gomes. "Neurotoxicity of Methylenedioxymethamphetamine (MDMA; Ecstasy) and its Main Metabolites, on Rat Brain Mitochondria In Vitro and In Vivo - Behavioral Consequences". Tese, Faculdade de Farmácia da Universidade do Porto, 2007. http://hdl.handle.net/10216/7499.

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Costa, Vera Marisa Freitas. "Role of catecholamines and reactive oxygen species in the mechanism of oxidative stress-induced heart disease:in vitro studies using fresly isolated rat cardiomyocytes". Tese, Faculdade de Farmácia da Universidade do Porto, 2008. http://hdl.handle.net/10216/20812.

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Oliveira, Ricardo Jorge Dinis. "Toxicity of Paraquat in Isolated Rat Lung. Search for Efficient Antidotes". Tese, Faculdade de Farmácia da Universidade do Porto, 2006. http://hdl.handle.net/10216/7369.

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The immune evasion mechanisms of pathogenic trypanosomatids involve a multitude of phenomena such as the polyclonal activation of lymphocytes, cytokine modulation and the enhanced detoxification of oxygen reactive species. A trypanothione-cascade seems to be involved in the detoxification process. We have recently described and characterized a tryparedoxin (LiTXN1) involved in the Leishmania infantum cytoplasmatic hydroperoxide metabolism. LiTXN1 is a secreted protein upregulated in the infectious form of the parasite, suggesting that it can play an important role during infection. In the present study, we investigated whether the recombinant LiTXN1 (rLiTXN1) would affect T and B cell functions in a murine model. We observed a significant increase of CD69 surface marker on the B-cell population in total spleen and on isolated B-cells from BALB/c mice after in vitro rLiTXN1 stimulus. Activated Bcells underwent further proliferation, as measured by an increased [3H]-thymidine incorporation. Cytokine quantification showed a dose-dependent upregulation of IL-10 secretion. B-cells were identified as a source. Furthermore, intraperitoneal injection of rLiTXN1 into BALB/c mice triggered the production of elevated levels of rLiTXN1 specific antibodies, predominantly of the IgM, IgG1 and IgG3 isotypes, with a minimum reactivity against other heterologous antigens. Taken together, our data suggest that rLiTXN1 could participate in the immunopathological processes by targeting the B-cells effector functions with subsequent IL-10 secretion and specific antibodies production.
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Libros sobre el tema "Toxicology"

1

Aldridge, W. Norman. Mechanisms and concepts in toxicology. London, UK: Taylor & Francis, 1996.

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D, Osweiler Gary y Galey Francis D, eds. Toxicology. Philadelphia: W.B. Saunders, 2000.

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1938-, Marquardt Hans, ed. Toxicology. San Diego: Academic Press, 1999.

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Holcomb, Michael L. International toxicology: Worldwide regulatory toxicology support. Eugene, OR: International Toxicology, 1995.

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A, Lewis Robert. Lewisʾ dictionary of toxicology. Boca Raton, Fla: Lewis Publishers, 1998.

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A, Lewis Robert. Lewisʼ dictionary of toxicology. Boca Raton, Fla: Lewis Publishers, 1996.

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Timbrell, John A. Introduction to toxicology. London: Taylor & Francis, 1989.

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Duffus, John y Howard Worth, eds. Fundamental Toxicology. Cambridge: Royal Society of Chemistry, 2007. http://dx.doi.org/10.1039/9781847552648.

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Woolley, David y Adam Woolley. Practical Toxicology. Third edition. | Boca Raton : Taylor & Francis, 2017. | Preceded by A guide to practical toxicology : evaluation, prediction, and risk /: CRC Press, 2017. http://dx.doi.org/10.1201/9781315157122.

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Anderson, Diana y D. M. Conning, eds. Experimental Toxicology. Cambridge: Royal Society of Chemistry, 1993. http://dx.doi.org/10.1039/9781847550798.

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Capítulos de libros sobre el tema "Toxicology"

1

Gregory, Peter. "Toxicology". En High-Technology Applications of Organic Colorants, 255–72. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3822-6_13.

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Allen, Brandon, Latha Ganti y Bobby Desai. "Toxicology". En Quick Hits in Emergency Medicine, 89–97. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7037-3_15.

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Gessner, Peter K. y Teresa Gessner. "Toxicology". En Disulfiram and its Metabolite, Diethyldithiocarbamate, 335–45. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2328-0_16.

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Lankas, George R. y Lea R. Gordon. "Toxicology". En Ivermectin and Abamectin, 89–112. New York, NY: Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4612-3626-9_6.

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Fowler, Murray E. y P. Walter Bravo. "Toxicology". En Medicine and Surgery of Camelids, 559–85. Ames, Iowa USA: Blackwell Publishing, Inc., 2013. http://dx.doi.org/10.1002/9781118785706.ch23.

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Marik, Paul Ellis. "Toxicology". En Handbook of Evidence-Based Critical Care, 479–500. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-86943-3_58.

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Varon, Joseph y Robert E. Fromm. "Toxicology". En Handbook of Practical Critical Care Medicine, 437–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-86945-7_16.

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Varon, Joseph y Pilar Acosta. "Toxicology". En Handbook of Critical and Intensive Care Medicine, 355–74. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-92851-7_16.

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Varon, Joseph. "Toxicology". En Handbook of Critical and Intensive Care Medicine, 375–95. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-31605-5_16.

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Zolnikov, Tara Rava. "Toxicology". En Autoethnographies on the Environment and Human Health, 81–95. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-69026-1_7.

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Actas de conferencias sobre el tema "Toxicology"

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Khalil, C. "Combining three in vitro assays for detecting early signs of UVB cytotoxicity in cultured human skin fibroblasts". En ENVIRONMENTAL TOXICOLOGY 2006. Southampton, UK: WIT Press, 2006. http://dx.doi.org/10.2495/etox060351.

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Duncan, K. "Spanish influenza: analogue for potential ramifications of bioterrorism". En ENVIRONMENTAL TOXICOLOGY 2008. Southampton, UK: WIT Press, 2008. http://dx.doi.org/10.2495/etox080011.

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Duncan, K. "Developing corporate environment and health strategy: review of existing corporate citizenship (CC) models". En ENVIRONMENTAL TOXICOLOGY 2008. Southampton, UK: WIT Press, 2008. http://dx.doi.org/10.2495/etox080041.

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Mueller, A., C. Graebsch, G. Wichmann, M. Bauer y O. Herbarth. "How to predict the potential effect of chemicals on human health: an extended question of environmental toxicology". En ENVIRONMENTAL TOXICOLOGY 2006. Southampton, UK: WIT Press, 2006. http://dx.doi.org/10.2495/etox060011.

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Paasivirta, J. "Estimation of vapour pressure, solubility in water, Henry’s law function, and Log Kow as a function of temperature for prediction of the environmental fate of chemicals". En ENVIRONMENTAL TOXICOLOGY 2006. Southampton, UK: WIT Press, 2006. http://dx.doi.org/10.2495/etox060021.

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D’Alessandro, W. "Human fluorosis related to volcanic activity: a review". En ENVIRONMENTAL TOXICOLOGY 2006. Southampton, UK: WIT Press, 2006. http://dx.doi.org/10.2495/etox060031.

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Papadimitriou, C., V. Evagelopoulos, P. Samaras, A. G. Triantafyllou, S. Zoras y T. A. Albanis. "Toxicity of atmospheric particulate matter using aquatic bioassays". En ENVIRONMENTAL TOXICOLOGY 2006. Southampton, UK: WIT Press, 2006. http://dx.doi.org/10.2495/etox060041.

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Fernández, P., R. Herruzo, A. Justel y F. Jaque. "Influence of ozone air contamination on the number of deaths ascribed to respiratory causes in Madrid (Spain) during 1990–1998". En ENVIRONMENTAL TOXICOLOGY 2006. Southampton, UK: WIT Press, 2006. http://dx.doi.org/10.2495/etox060051.

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Mankiewicz-Boczek, J., K. Izyorczyk y T. Jurczak. "Risk assessment of toxic Cyanobacteria in Polish water bodies". En ENVIRONMENTAL TOXICOLOGY 2006. Southampton, UK: WIT Press, 2006. http://dx.doi.org/10.2495/etox060061.

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Ivanov, V. "Bacteriological monitoring of ships’ ballast water in Singapore and its potential importance for the management of coastal ecosystems". En ENVIRONMENTAL TOXICOLOGY 2006. Southampton, UK: WIT Press, 2006. http://dx.doi.org/10.2495/etox060071.

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Informes sobre el tema "Toxicology"

1

Travis, C. (Environmental toxicology). Office of Scientific and Technical Information (OSTI), noviembre de 1988. http://dx.doi.org/10.2172/7098533.

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2

Retterer, S. T. y M. P. Holsapple. Multiscale Toxicology- Building the Next Generation Tools for Toxicology. Office of Scientific and Technical Information (OSTI), octubre de 2013. http://dx.doi.org/10.2172/1105981.

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3

Thrall, Brian D., Kevin R. Minard, Justin G. Teeguarden y Katrina M. Waters. Multiscale Toxicology - Building the Next Generation Tools for Toxicology. Office of Scientific and Technical Information (OSTI), septiembre de 2012. http://dx.doi.org/10.2172/1054854.

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4

Schlyer, David y Michael Furey. Multi-Scale Toxicology: Building the Next Generation of Tools for Toxicology. Office of Scientific and Technical Information (OSTI), diciembre de 2013. http://dx.doi.org/10.2172/1108700.

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Kun, Ernest. Molecular Toxicology of Chromatin. Fort Belvoir, VA: Defense Technical Information Center, enero de 1992. http://dx.doi.org/10.21236/ada247307.

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6

Starke, William C., David C. Burnett, Roger J. Hilaski, James H. Manthei y Dale H. Heitkamp. Developmental Toxicology of Methylphosphonic Difluoride (DF). Fort Belvoir, VA: Defense Technical Information Center, septiembre de 1988. http://dx.doi.org/10.21236/ada199597.

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7

Lu, Po-Yung. The installation restoration program toxicology guide. Office of Scientific and Technical Information (OSTI), julio de 1989. http://dx.doi.org/10.2172/5251628.

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8

Archuleta, M. M. Aqueous foam toxicology evaluation and hazard review. Office of Scientific and Technical Information (OSTI), octubre de 1995. http://dx.doi.org/10.2172/114035.

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Archuleta, M. M. Oleoresin Capsicum toxicology evaluation and hazard review. Office of Scientific and Technical Information (OSTI), octubre de 1995. http://dx.doi.org/10.2172/120857.

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Turner, J. E. (Quantitative structure-activity relationships in environmental toxicology). Office of Scientific and Technical Information (OSTI), octubre de 1990. http://dx.doi.org/10.2172/6613721.

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