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Tesis sobre el tema "Tissue Treg"

Autor: Grafiati

Publicado: 25 de mayo de 2024

Última modificación: 31 de julio de 2025

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1

Tariq, Mubashira. "IL-33/ST2 and tissue Treg/AREG pathways in the pathophysiology of HIV infection." Electronic Thesis or Diss., Paris 12, 2021. http://www.theses.fr/2021PA120017.

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Depuis les thérapies antirétrovirales (ART), les principales causes de mortalité et de morbidité sont liées à des pathologies non liées aux SIDA qui sont dûes à un niveau d’inflammation chronique de bas bruit. Cette inflammation est liée entre autre à la persistance de la perte d’homéostasie intestinale qui conduit à des translocations microbiennes dans la circulation systémique. En effet, les sujets traités et infectés par le VIH présentent une déplétion sévère et massive des lymphocytes T CD4+, en particulier dans le tissu lymphoïde associé à l'intestin (GALT) une altération de la barrière é

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2

Kolodin, Dmitriy Pavlovich. "Dynamics of Tissue-Resident Regulatory T Cell Populations." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11555.

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In recent years, there has been a worldwide increase in obesity, which parallels a rise in pathologies, including type 2 diabetes, collectively termed the metabolic syndrome. Chronic, low-grade inflammation has been implicated as a major link between these diseases. Recent work showed the presence of a unique subset of CD4+Foxp3+ regulatory T cells residing in visceral adipose tissue (VAT Treg) with PPAR-g being the key transcription factor responsible for their phenotype and function in controlling adipose tissue inflammation and, thereby, insulin sensitivity. VAT Tregs inversely correlated w

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3

Cooley, Lauren Folgosa. "The role of ADAM10, ADAM17, and Spag6 in humoral immunity and secondary lymphoid tissue architecture." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3808.

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ADAM10, ADAM17, and SPAG6 contribute significantly to humoral immunity and secondary lymphoid tissue architecture. ADAM10 and ADAM17 are two closely related zinc-metalloproteinases. Through cleavage of their ligands CD23 and TNF, respectively, they greatly influence IgE production and secondary lymphoid tissue architecture maintenance. Th1 prone WT strains initially exhibit increased ADAM17 and TNF yet reduced ADAM10 relative to Th2 prone WT strains. In the absence of B cell ADAM10, a compensatory increase in ADAM17 and TNF cleavage is noted only in Th1 prone C57Bl/6, not Th2 prone Balb/c. B c

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4

Mubarak, Ayman. "Characterisation of Treg and Th17 cells in nasopharynx-associated lymphoid tissue and their association with pneumococcal carriage in children and adults." Thesis, University of Liverpool, 2014. http://livrepository.liverpool.ac.uk/2010261/.

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Streptococcus pneumoniae (pneumococcus) is a gram-positive bacterium that can cause significant morbidity and mortality in humans especially in children and elderly. T regulatory cells (Treg) have an important role in modulation of immune responses to microbial infection. Although Th17 cells are involved in autoimmune diseases, these cells may play a protective role against pathogens. In this PhD project, Th17 and Treg cells in nasal-associated lymphoid tissue were characterised and their relationship with nasopharyngeal carriage of pneumococcus studied in children and adults. Frequencies of T

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5

Varikuti, Sanjay. "Role of CD4+CD25+ Regulatory T Lymphocytes in Experimental Toxoplasmosis." TopSCHOLAR®, 2009. http://digitalcommons.wku.edu/theses/113.

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Toxoplasmosis is an important cause of congenital disease, and it is one of the most common opportunistic infections in patients with acquired immunodeficiency syndrome. The need for a reliable experimental model of this infection is crucial not only for achieving a better understanding of the patho-physiology of the disease, but also for developing better methods for evaluating new therapeutic regimens. The purpose of the present study was to investigate the role of CD4+CD25+ T regulatory lymphocytes in mice infected with Toxoplasma gondii. T regulatory (Treg) cells have been shown to play an

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6

Hewavisenti, Rehana Vishvangani. "Tissue Resident T Cells In Human Disease." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/23635.

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Tissue resident memory T cells are a subset of memory T cells that reside in tissue permanently, without entering circulation. Their strategic location at sites of common pathogen entry or reinfection, provides a critical advantage for controlling infections. While their role in infection control has become clear, whether tissue-resident T cells can contribute to immune homeostasis or play a role in cancer is unclear. In this study, we investigated the role of tissue-resident T cells in tissue homeostasis and cancer. We show that tissue-resident regulatory T cells exist in human lymphoid tissu

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7

MONTOYA, CYNARA V. "Desenvolvimento de um sistema computacional de gerenciamento de riscos em processos de radioesterilizacao de tecidos biologicos." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9528.

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Made available in DSpace on 2014-10-09T12:27:40Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:04:16Z (GMT). No. of bitstreams: 0<br>Tese (Doutoramento)<br>IPEN/T<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

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8

Mehta, U. J. "Tissue culture studies in tamarind (tamarindus indica L.), a leguminous tree species." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2001. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2864.

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9

Sinha, Debleena. "Development of an In Vitro Protoplast Culture System for Albizia Lebek (L.) Benth., an Economically Important Leguminous Tree." Thesis, University of North Texas, 1998. https://digital.library.unt.edu/ark:/67531/metadc500422/.

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An in vitro system of generating protoplasts from their callus cultures was established. The friable callus was more productive in terms of producing protoplasts than the green compact callus. The concentration of the various cell wall degrading enzymes had an effect on the viability of the protoplasts in the medium. The protoplast system developed from the experiments was stable and could be used for the transformation experiments of Albizia lebek and for other plant improvement practices.

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10

Hughes, Steven. "The use of magnetic particles in tissue engineering : selective activation of the mechanosensitive ion channel TREK-1." Thesis, Keele University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423423.

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Over recent years there has been growing focus on the potential of tissue engineering approaches to produce functional bone tissue for clinical use. This thesis highlights the potential for using magnetic particle based techniques for tissue engineering applications. This study demonstrates that magnetic micro-- and nano scale particles are well tolerated by human osteoblasts over prolonged periods of time, and can be used to stimulate calcium signalling pathways in these cells. via the application offorces to integrin rc<:eptors and the internal cytoskeleton. Furthennore, this study demonstra

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11

Sujatha, K. "Tissue culture studies and molecular characterization of pongamia (pongamia pinnata(L.)pierre),an oil producing tree legume." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2007. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2572.

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12

Spokevicius, Antanas Vytas. "The use of induced somatic sectors for the elucidation of gene function and developmental patterns in xylogenic tissue /." Connect to thesis, 2006. http://eprints.unimelb.edu.au/archive/00002300.

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13

Roubanis, Aristeidis. "Investigating the metabolism of regulatory T cells in non-lymphoid tissues using a genetic approach and an in vivo adaptation of SCENITH." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS321.pdf.

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La régulation du métabolisme cellulaire est un élément central gouvernant le destin et la fonction des cellules T. Parmi les cellules T, les cellules T régulatrices CD4+ Foxp3+ (Tregs) sont essentielles pour le maintien de la tolérance au soi et de l'homéostasie immunitaire. Les Tregs sont présentes dans les tissus lymphoïdes où elles contrôlent les réponses immunitaires et dans divers tissus non-lymphoïdes où elles maintiennent l'homéostasie tissulaire. Les précurseurs des Tregs colonisant les tissus non-lymphoïdes sont présents dans la rate et les ganglions lymphatiques et subissent des étap

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14

Rimland, Casey. "Understanding regional diversity in the human biliary tree through transcriptomic profiling of primary tissues and in vitro derived organoids." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/286011.

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The biliary tree is a series of ductular tissues responsible for the drainage of bile produced by the liver and pancreatic secretions from the pancreas. The biliary tree is affected by a diversity of life- threatening diseases collectively called cholangiopathies. Cholangiopathies show regionalization, with some diseases such as biliary atresia predominantly targeting extrahepatic bile ducts (EHBDs) outside of the liver. Despite this, little is known on whether anatomical location within the biliary tree contributes to differences in functionality of biliary epithelium, especially in the EHBD

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15

Pascone, Valeria. "Piramo e Tisbe, Narciso e Semele : tre miti ovidiani in Dante." Thesis, Grenoble, 2012. http://www.theses.fr/2012GRENL036.

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La thèse, intitulée "Tre miti ovidiani in Dante : Piramo e Tisbe, Narciso e Semele" est une analyse de la présence de ces trois fabulae des Métamorphoses dans l'œuvre de Dante. La sélection des mythes a été dictée par la nécessité de définir un champ aussi vaste et par l'intention de mettre en évidence la relation entre l'Eros et la Connaissances, qui est si important dans le système poétique et philosophique de l'auteur florentin.Cette étude se fie par ailleurs l'objective de souligner la manière dont Dante utilise le modèle d'Ovide: la rencontre avec la source classique prévoit un dialogue c

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16

Kärkönen, Anna. "Plant tissue cultures as models for tree physiology : somatic embryogenesis of Tilia cordata and lignin biosynthesis in Picea abies suspension cultures as case studies." Helsinki : University of Helsinki, 2002. http://ethesis.helsinki.fi/julkaisut/mat/bioti/vk/karkonen/.

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17

Essien, Kingsley I. "Understanding regulatory factors in the skin during vitiligo." eScholarship@UMMS, 2018. https://escholarship.umassmed.edu/gsbs_diss/1015.

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Vitiligo is an autoimmune disease of the skin characterized by epidermal depigmentation that results from CD8+ T cell-mediated destruction of pigment producing melanocytes. Vitiligo affects up to 1% of the population and current treatments are moderately effective at facilitating repigmentation by suppressing cutaneous autoimmune inflammation to promote melanocyte regeneration. In order to cause disease, CD8+ T cells must overwhelm the mechanisms of peripheral tolerance in the skin and if we understand the suppressive mechanisms that are compromised during vitiligo, we can potentially use this

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18

Yaganti, Sushmita. "Immunolocalization and Changes in Expression Levels of Glyceroporin HC-3 in Several Tissues of Gray Tree Frogs, Hyla chrysoscelis Under Different Physiological Conditions." Wright State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=wright1239987029.

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19

Gueye-Follet, Marie-Laure. "Relations ioniques dans l'activité cambiale et la xylogénèse : approche par microscopie ionique analytique." Rouen, 1997. http://www.theses.fr/1997ROUES050.

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Ce mémoire présente une approche par Microscopie Ionique Analytique (MIA) des relations ioniques dans l'activité cambiale et la xylogénèse chez deux modèles expérimentaux : le pin sylvestre (pinus sylvestris L. ) Et le hêtre (fagus sylvatica L. ). Ce travail comporte des mises au point méthodologiques concernant la préparation des échantillons ligneux et les conditions instrumentales de l'analyse en MIA. Nous avons mis au point une nouvelle méthode de préparation des échantillons végétaux, la fixation - déshydratation en phase vapeur, qui assure une bonne conservation des ultrastructures cellu

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20

Santos, Ant?nio de P?dua dos. "Imagin?rio radical e educa??o f?sica: trajet?ria esportiva de corredores de longa dist?ncia." Universidade Federal do Rio Grande do Norte, 2008. http://repositorio.ufrn.br:8080/jspui/handle/123456789/14170.

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Made available in DSpace on 2014-12-17T14:35:57Z (GMT). No. of bitstreams: 1 AntonioPS.pdf: 1422474 bytes, checksum: 56eb2f26bc9793947acf218454e0cb2d (MD5) Previous issue date: 2008-11-14<br>Cette ?tude propose une lecture du sport d endurance, prenant comme perspective th?orique l imaginaire radical et consid?rant les dimensions socio-historiques e subjectives de la pratique de courses de longue distance. D abord, l ?chantillon la recherche a ?t? compos? de huit sujets-atl?tes du groupe de courreurs de rue Sport Vida. Ainsi, em m?me temps que nous f

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21

Tambarussi, Evandro Vagner. "Desenvolvimento de metodologias biotecnológicas para micropropagação, regeneração e transformação genética de teca (Tectona grandis L. f) visando resistência a Hyblaea puera." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/11/11144/tde-16032010-133003/.

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A transformação genética possibilita a introdução de genes de interesse nos genomas, podendo assim ser empregada na tentativa de melhorar características agronômicas e florestais. No entanto, para a obtenção de plantas transgênicas são necessários protocolos eficientes de regeneração de plantas in vitro. Em teca, dados sobre cultura de tecidos são escassos, havendo a necessidade de determinar condições ótimas para a mesma. Com isso, o trabalho teve por objetivos estudar a organogênese in vitro de teca visando desenvolver um método de regeneração eficiente, avaliar condições para o processo de

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22

Lelu, Marie-Anne. "Embryogenese somatique chez picea abies l. Karst. A partir de cotyledons de jeunes plantes." Paris 6, 1987. http://www.theses.fr/1987PA066485.

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Les travaux relatant l'embryogenese somatique chez les gymnospermes sont encore recents et n'ont ete realises qu'a partir de materiel tres juvenile. C'est ce genre d'explant que nous avons utilise comme temoin pour caracteriser et visualiser l'embryogenese somatique. Nous avons par la suite obtenu ce phenomene a partir de cotyledons de jeunes plantes agees de 3 a 7 jours apres germination, places directement en conditions de callogenese. Cependant, le taux de cals embryogenes est ameliore quand les cotyledons subissent un traitement caulogene d'une semaine prealablement; dans nos meilleures co

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23

Levionnois, Sébastien. "Diversité et variabilité de l’architecture vasculaire et hydraulique de la pousse feuillée chez des arbres de canopée d’une forêt tropicale humide Scaling of petiole anatomies, mechanics, and vasculatures with leaf size in the widespread Neotropical pioneer tree species Cecropia obtusa Trécul (Urticaceae) Linking drought-induced embolism resistance in stem xylem tissue to multi-scale wood anatomical traits of Neotropical trees." Thesis, Guyane, 2019. http://www.theses.fr/2019YANE0011.

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Les traits hydrauliques sont reliés aux fonctions fondamentales du transport de l’eau dans la plante et de la résistance à la sécheresse, déterminant l’écologie, l’évolution, et les processus en lien avec le changement climatique pour les plantes. Cependant, ces traits restent que peu documentés pour les forêts tropicales humides, empêchant de mieux comprendre l’écologie des arbres tropicaux et le futur des forêts tropicales. À partir d’une approche générale s’intéressant à la structure (morphologie et anatomie) et au fonctionnement (physiologie) de la pousse feuillée au sein des arbres, cette

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24

CHOUFFOT, STRUYCKEN BARBARA. "Contribution a l'etude des capacites de multiplication vegetative du shorea curtisii dyer ex king, diphterocarpaceae de malaisie." Strasbourg 1, 1986. http://www.theses.fr/1986STR13138.

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Surexploitee pour son bois, infeodee pour son developpement a une mycorhization, dependant d'une production de semences episodique et d'une germination aleatoire, shorea curtisii, incapable en outre de multiplication vegetative spontanee ou par les procedes traditionnels, est tres representatif des dipterocarpacees asiatiques menacees d'extinction rapide. Une mise au point d'un procede de micropropagation in vitro contribuerait a sauvegarder l'espece. L'observation, chez shorea curtisii, de galles epiphylles a organisation de bourgeon abortif suggerant une certaine aptitude des feuilles a la n

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25

Grellier, Brigitte. "Approche biotechnologique des mycorhizes : culture in vitro et physiologie des associations ectomycorhiziennes." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37605677t.

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26

Bekkaoui, Faouzi. "Microbouturage in vitro et culture de méristèmes de Douglas (Pseudotsuga menziesii) : problèmes liés à l’âge et au milieu de culture." Paris 6, 1986. http://www.theses.fr/1986PA066383.

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La multiplication des microboutures au cours des subcultures est caractérisée par une évolution de l'état physiologique qui dépend de l’âge, des réserves nutritives et du milieu de culture. Parmi les problèmes qui limitent la multiplication végétative: l'hyperhydrie et le gonflement des tiges des microboutures. Le premier est caractérisé par une teneur en eau élevée, par des rapports p/na, k/na et cytokinines/auxine élevés. Le deuxième est caractérisé par une teneur élevé en zéatine+zéatine-riboside. Les méristèmes de plantes d'âges différents ont une réactivité distincte aux niveaux morpholog

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27

Chevalier, Michel. "Contribution a l'etude des relations hote-parasite dans le cas du couple malus x domestica-venturia inaequalis : etude histologique et cytologique de deux cas de resistance dependant des genes vf et vm." Nantes, 1988. http://www.theses.fr/1988NANT2030.

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Expression de la resistance selon les races et les hybrides vm et vf. Caracterisation de l'hypersensibilite codee par le genie vm. Etude comparative des classes de symptomes liees a la resistance codee par le gene vf. Caracterisation des differences d'hypersensibilite dans 2 cas

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28

Louerguioui, Ali. "Techniques de multiplication par clonage "in vitro" du genre eucalyptus." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37615472r.

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29

BUTERA, ALESSIA. "Role of regulatory cells and tissue cytokines in patients with ulcerative colitis: implications for patient-oriented therapy." Doctoral thesis, 2020. http://hdl.handle.net/11573/1362033.

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Ulcerative colitis (UC) is an inflammatory bowel disease that results in a chronic inflammation and ulcers of the mucosa of the colon. In UC, two important issues, specifically related to the prognosis, remain to be clarified. A) Extension of disease greatly influences the prognosis and biological factors involved in the limitation of the disease extent are presently unknown B) Due to increased availability of biological drugs targeting different cytokines, biological therapy need to be optimized on the key cytokine(s) relevant for the inflammatory process. Aim: A) We hypothesized that regulat

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30

Maila, Yvonne Mmatshelo. "In-vitro propagation of Mmupudu (Mimusops zeyheri) fruit tree." Thesis, 2001. http://hdl.handle.net/10386/2080.

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31

Xia, Jun. "STATISTICAL MODELS AND ANALYSIS OF GROWTH PROCESSES IN BIOLOGICAL TISSUE." 2016. http://scholarworks.gsu.edu/math_diss/39.

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The mechanisms that control growth processes in biology tissues have attracted continuous research interest despite their complexity. With the emergence of big data experimental approaches there is an urgent need to develop statistical and computational models to fit the experimental data and that can be used to make predictions to guide future research. In this work we apply statistical methods on growth process of different biological tissues, focusing on development of neuron dendrites and tumor cells. We first examine the neuron cell growth process, which has implications in neural tissu

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32

Lin, Yu Cheng, and 林育正. "Embryonic, Young Floret, and Endospermic Tissue Cultures and Somatic Embryogenesis of Fringe Tree (Chionanthus retusus Lindl.)." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/99706124078848364271.

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碩士<br>臺灣大學<br>園藝學研究所<br>95<br>The fringe tree (Chionanthus retusus Lindl.) is a graceful flowering tree which tree crown is beautiful. It would like snowing on tree when fringe is flowing. Fringe tree is considered as a rare species and limited population in Taiwan. There is epicotyl dormancy on the seed and hard to rooting through cutting. The purpose of this research is to induce callus formation from endosperm, young floret, derived embryogenic cell for suspension culture, and embryo tissue, to study embryonic tissue cultures and somatic embryogenesis. Endosperm culture before glutinous sta

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33

Yun, Yejin Esther. "Development of a correlation based and a decision tree based prediction algorithm for tissue to plasma partition coefficients." Thesis, 2013. http://hdl.handle.net/10012/7483.

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Physiologically based pharmacokinetic (PBPK) modeling is a tool used in drug discovery and human health risk assessment. PBPK models are mathematical representations of the anatomy, physiology and biochemistry of an organism. PBPK models, using both compound and physiologic inputs, are used to predict a drug’s pharmacokinetics in various situations. Tissue to plasma partition coefficients (Kp), a key PBPK model input, define the steady state concentration differential between the tissue and plasma and are used to predict the volume of distribution. Experimental determination of these paramete

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34

Sajjad, Ashif, and Giovanni Sindona. "Biochemistry of olive tree. From genomic to proteomic application on different olive tissues and oil." Thesis, 2006. http://hdl.handle.net/10955/733.

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35

Patel, Nimit. "Feasibility study of an ultra fast gated camera to image biliary tree embedded in adipose tissue using laboratory phantoms and Monte Carlo simulations." 2008. http://hdl.handle.net/10106/1862.

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36

Thokoane, Novungayo Lucy. "The development of short-to-medium and long-term germplasm storage protocols for Eucalyptus spp." Thesis, 1998. http://hdl.handle.net/10413/4695.

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Eucalyptus trees are a significant source of fuelwood, timber and raw material for the paper and pulp industry. In South Africa, Eucalyptus grandis and its hybrids are in high demand due to their fast growth and suitability of their timber for a wide range of products. Breeding and selection for superior quality eucalypts could sustain this high demand through selection and subsequent multiplication of superior genotypes and their use in controlled crosses. However, for this to be successful, a wide genepool must be available and maintained. Germplasm conservation of both vegetative and sexual

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