Tesis sobre el tema "Tissue application"
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Ueda, Yuichiro. "Application of Tissue Engineering with Xenogenic Cells and Tissues for Regenerative Medicine". 京都大学 (Kyoto University), 2004. http://hdl.handle.net/2433/147657.
Texto completoBERNOCCO, MARCO. "Bioreactor engineering for tissue engineering application". Doctoral thesis, Politecnico di Torino, 2013. http://hdl.handle.net/11583/2513796.
Texto completoYuan, Tai-Yi. "Innovative Methods to Determine Material Properties of Cartilaginous Tissues and Application for Tissue Engineering". Scholarly Repository, 2011. http://scholarlyrepository.miami.edu/oa_dissertations/607.
Texto completoHalili, Ndreu Albana. "Collagen-based Meniscus Tissue Engineering: Design And Application". Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613451/index.pdf.
Texto completoC followed by lyophilization. The middle and bottom layers were made with just collagen after freezing at -20º
C and -80º
C, respectively and lyophilization. Aligned nano/microfibers were prepared using collagen-poly(L-lactic-co-glycolic acid (Coll-PLGA). Various crosslinking procedures such as 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide (EDC/NHS), genipin (GP), glutaraldehyde (GLU) either alone or in combination with dehydrothermal treatment (DHT) were used and based on both compressive and tensile properties, the best crosslinker was chosen to be DHT+EDC/NHS. Mechanical properties (compressive, tensile and shear) of the dry foams and the final 3D construct were evaluated. The highest mechanical properties were obtained with the 3D construct. Then all these foams and the 3D construct were seeded with human fibrochondrocytes to study the cell behavior such as attachment, proliferation, and extracellular matrix (ECM) and glucosaminoglycan (GAG) production. Furthermore, the influence of cell seeding on the compressive properties of wet individual foams and the 3D construct was observed. As expected, the highest cell proliferation and compressive properties were obtained with the 3D construct. Finally, the 3D constructs, seeded with fibrochondrocytes, were implanted in New Zealand rabbits after meniscectomy. The initial microscopical examination show that the 3D construct has a significant potential as a meniscus substitute.
Walsh, Pamela Judith. "Natural calcium phosphate ceramics for tissue engineering application". Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486236.
Texto completoAarvold, Alexander. "Bone tissue engineering : experimental strategies and clinical application". Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/362817/.
Texto completoSchill, Markus A. "Biomechanical soft tissue modeling techniques, implementation and application /". [S.l. : s.n.], 2002. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB10605020.
Texto completoGagliardi, Davide. "Le paradigme de la Matryoshka : Application à l'homogénéisation stochastique des propriétés matérielles du tissu osseux". Thesis, Paris Est, 2016. http://www.theses.fr/2016PESC1115/document.
Texto completoThe hierarchical structure of bone tissues, as well as the heterogeneity and anisotropy of its physical properties and the uncertainty on in vivo experimental measures make it impossible to establish a deterministic reliable model of bone mechanical properties. Aiming at providing a valuable aide to diagnostics in orthopaedic, the purpose of this thesis is to develop a robust mechanical model able to account for the experimental uncertainty.Therefore we developed a multi-scale stochastic model, based on continuum micromechanics and maximum entropy principle which has proved effective predicting the heterogeneous and anisotropic elastic properties of bone tissue at the organ scale accounting for experimental uncertainty affecting image-based input data.Aiming to clarify the mechanism of propagation of these uncertainties through the chosen principal multi-scale model, others versions have been analyzed. First, the principal model, which uses the volume fractions of the essential constituents (mineral, water, collagen), as primary variables, has been analyzed scale-by-scale (mineral foam, ultra-structure, cortical bone). The effect of the chosen homogenization methods and volume fractions on the resulting composites (as layers of a random Matryoshka) have been discussed. Thanks to this analysis, this model has been simplified and relied directly to the measures straightly accessible form medical imaging of the bone: the tissue mineral density (TMD) and the haversian porosity (HP) and their calibration at millimeter scale. This version of the stochastic model, proved to be as accurate as the proceeding one and, more effective in the description of the bone.Finally, the stochastic model of bone has been completed with the direct modeling of the elastic tensors of the involved materials. For this purpose, the random matrix theory has been applied. This theory can be seen as another declination of the Matryoshka paradigm. In this case, the uncertainty on the random tensor propagate from the inside (random germ) to outside (each layer of random matrix) through a suitable sequence of nonlinear operations. Thanks to the proposed decomposition, at once, the isotropic material class of the resulting material and his spatial variability has been included in the model
Åkesson, Elisabet. "Human spinal cord transplantation : experimental and clinical application /". Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4322-2/.
Texto completoHeus, Redha. "Approches virtuelles dédiées à la technologie des puces à tissus "Tissue MicroArrays " TMA : Application à l'étude de la transformation tumorale du tissu colorectal". Phd thesis, Université Joseph Fourier (Grenoble), 2009. http://tel.archives-ouvertes.fr/tel-00429056.
Texto completoPašović, Mirza. "Tissue harmonic reduction : application to ultrasound contrast harmonic imaging". Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10060.
Texto completoUltrasound contrast agents are small micro bubbles that respond nonlinearly when exposed to ultrasound wave. The nonlinear response gives possibility of harmonic ultrasound images which has many advantages over fundamental imaging. However, to increase ultrasound contrast harmonic imaging performance we must first understand nonlinear propagation of ultrasound wave. Nonlinear propagation distorts the propagating wave such that higher harmonics appear as the wave is propagating. The theory that was laid down, was allowed implementing a new method of modelling nonlinear ultrasound propagation. The knowledge obtained during this process was used to construct a multiple component second harmonic reduction signal for reduction of their harmonics generated due to the tissue nonlinearities. As a consequence detection of ultrasound contrast agents at higher harmonics was increased. Further more, a powerful ultrasound imaging technique called Pulse Inversion, was further enhanced with multiple component second harmonic reduction signal. What was learned during investigation of the Pulse Inversion, technique lead to a new phase coded ultrasound contrast harmonic method called second harmonic inversion;. Also it was noted that for different type of media the level of distortion of ultrasound pulse is different. It depends largely on the nonlinear parameter B / A. Although the work on this parameter has not been finished it is very important to continue in this direction since B / A imaging with ultrasound contrast agents has a lot of potential
Kao, Ruey-Ho. "Application of differential display technique to breast cancer tissue". Thesis, King's College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342256.
Texto completoSmith, James Oliver. "Bone tissue engineering : harnessing interdisciplinary approaches for clinical application". Thesis, University of Southampton, 2013. https://eprints.soton.ac.uk/364931/.
Texto completoRotar, O. V. y V. I. Rotar. "Application of Chitosan / Cyclodextrin Nanoparticles for Tissue Glutathione Delivery". Thesis, Sumy State University, 2013. http://essuir.sumdu.edu.ua/handle/123456789/35422.
Texto completoNedjari, Salima. "Microstructuration of nanofibrous membranes by electrospinning : application to tissue engineering". Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAE027/document.
Texto completoThe aim of this thesis was to develop new architectured nanofibrous biomaterials (2D or 3D) using the electrospinning method and to study the influence of these nanofibrous structures on bone cells behaviors. Electrospinning is a technique allowing the production of nanofibers by projecting, under the action of a strong electric field, a polymer solution on a collector. The nanofibers are generally randomly deposited and form mats or scaffolds. These scaffolds are interesting for tissue engineering applications because of their structure mimicking the extracellular matrix of living tissues. However, it has been shown that when the collector is microstructured, it is possible to control the organization of the fibers during their deposition through the local perturbation of the electric field at the vicinity of the surface of the collector. These micropatterned collectors act as "electrostatic templates". First, 2D honeycomb nanofibrous scaffolds were elaborated using micropatterned honeycomb collectors during the electrospinning process. These scaffolds were made either with poly(ε-caprolactone) (PCL) or poly(lactic acid) (PLA). We showed that the morphology of the PCL nanofibers (bimodal distribution of the fiber diameter) led to a scaffold with a strong relief. Despite, with PLA fibers which presented a monomodal distribution of the fiber diameter, the obtained scaffolds were much flatter. It was possible to control the spatial organization of bone-like cells MG-63 (osteoblasts), playing on the relief and the architecture of the scaffold. Subsequently, 3D materials were elaborated using micropatterned collectors in order to open new paths for the development of filling materials for bone regeneration. Microstructuration of PCL nanofibers (by the use of micropatterned honeycomb collector during the electrospinning process) coupled with the self-assembling properties of the PCL lead to the development of new 3D nanofibrous scaffolds, with controlled pore size and porosity gradient in the thickness of the scaffold. Afterwards, micropatterned composite 2D and 3D membranes were elaborated. By coupling the process of electrospinning with the process of electrospraying on micropatterned collector, we demonstrated that we can deposit the particles in a controlled way, especially on the walls of honeycomb patterns thanks to the presence of a thin fiber layer first deposited on the collector. This thin nanofiber layer plays the role of an "electrostatic template" for the particles deposition. Thereafter, this technique was applied to develop bilayers composite nanofibrous membranes containing PCL nanofibers and hydroxyapatite (HA) microparticles. These membranes consisted of 21 different microarchitectures (bars, blocks, hexagons, maze) were then incorporated into a small cell culture plate, thereby forming a new type of biochip for the screening of nanofibrous architectures. Indeed, these biochips allowed the screening of nanofibrous microarchitectures to identify the most relevant for bone regeneration. It turned out that the HA hexagonal structures (with an average diameter of 300 microns) and circular HA structures (with an average diameter of 150 microns) are the structures that enhance the most the mineralization process of bone cells. Finally, by combining simultaneously electrospinning nanofibers and electrospraying particles on micropatterned honeycomb collector, 3D composite scaffolds were elaborated. It was possible to control the size of cylindrical pores of these 3D composite from tens to hundreds of microns by changing the size of the honeycomb patterns of the collector
Richter, Katrin. "Application of imaging TOF-SIMS in cell and tissue research /". Göteborg : Institute of Biomedicine, The Sahlgrenska Academy, Göteborg University, 2007. http://hdl.handle.net/2077/7447.
Texto completoXie, Dan y 謝丹. "Application of high-throughput tissue microarray technology in cancer research". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B30283619.
Texto completoHoran, Imelda. "Tissue culture of roses and its application to rose breeding". Thesis, University of East London, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239147.
Texto completoHarding, Sarah Ione. "Characterisation of a fibronectin material for application in tissue engineering". Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312319.
Texto completoSitsanidis, Efstratios D. "Controlling the interfaces of supramolecular hydrogels for tissue culture application". Thesis, University of Kent, 2018. https://kar.kent.ac.uk/69466/.
Texto completoLu, Jiang. "Transforms for multivariate classification and application in tissue image segmentation /". free to MU campus, to others for purchase, 2002. http://wwwlib.umi.com/cr/mo/fullcit?p3052195.
Texto completoChaves, Vieira Lins Luanda. "Study and development of electrospun fibers for biotechnology application". Thesis, Lyon, 2016. http://www.theses.fr/2016LYSEI073.
Texto completoCurrently, the electrospinning process is also one of the most promising routes for the design and development of polymer fibers. This technique is easy to use, unique, versatile, and low cost, which can be used to create fibers from a variety of starting materials. The structure, chemical and mechanical stability, functionality, and other properties of the fibers can be modified to match end applications. The first goal of this thesis was to develop scaffolds for the field of neural tissue engineering in order to mimic the biological, physical and mechanical properties of the native extracellular matrix. In the first time, the effect of fiber alignment of a biocompatible and fluorinated matrix denoted polyvinylidene fluoride (PVDF) was studied on the behavior of monkey neural stem cells particularly the morphology, cell adhesion and their differentiation in glial or neuronal cells. Secondly, bioabsorbable scaffolds composed of polylactide (PLA) and polyethylene glycol (PEG) polymers were synthesized to investigate the influence of the hydrophilic-hydrophobic balance on the culture of neural stem cells. Finally, an exploratory work was conducted to develop smart textiles based on poly(butylene adipate-co-terephthalate) (PBAT) containing curli as protein, well-known for its ability to chelate metals
Warner, Joshua. "Developments in 2D NMR relaxometry and its application to biological tissue". Thesis, University of East Anglia, 2010. https://ueaeprints.uea.ac.uk/48040/.
Texto completoHatem, Iyad. "Hybrid multivariate classification technique and its application in tissue image analysis /". free to MU campus, to others for purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3091929.
Texto completoWarman, Eduardo Norberto. "Modulation of neuronal firing with applied currents". Case Western Reserve University School of Graduate Studies / OhioLINK, 1992. http://rave.ohiolink.edu/etdc/view?acc_num=case1060010722.
Texto completoOldenziel, Weite Hendrik. "Application of a glutamate microsensor to brain tissue construction, evaluation and application of a glutamate microsensor /". [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2006. http://irs.ub.rug.nl/ppn/297660691.
Texto completoNam, Jin. "Electrospun polycaprolactone scaffolds under strain and their application in cartilage tissue engineering". Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1157828634.
Texto completoTong, Ho-wang y 唐灝泓. "Electrospinning of ultrafine fibers and its application in forming fibrous tissue engineering scaffolds". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hdl.handle.net/10722/205827.
Texto completoTong, Ho-wang. "Electrospinning of ultrafine fibers and its application in forming fibrous tissue engineering scaffolds". Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42841173.
Texto completoFujita, Satoshi. "Development and Application of Microenvironment for Regulation of Stem Cell Behaviors". 京都大学 (Kyoto University), 2008. http://hdl.handle.net/2433/70026.
Texto completo0048
新制・課程博士
博士(工学)
甲第14264号
工博第3015号
新制||工||1448(附属図書館)
26591
UT51-2008-T24
京都大学大学院工学研究科高分子化学専攻
(主査)教授 岩田 博夫, 教授 伊藤 紳三郎, 教授 大嶋 正裕
学位規則第4条第1項該当
Swim, Megan Marie. "Stem cell tissue engineering and potential application in corrective congenital heart surgery". Thesis, University of Bristol, 2017. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.723504.
Texto completoStone, Nicholas. "Raman spectroscopy of biological tissue for application in optical diagnosis of malignancy". Thesis, Cranfield University, 2001. http://dspace.lib.cranfield.ac.uk/handle/1826/4015.
Texto completoD'Entremont, Matthew Ivan. "The application of impedance spectroscopy to assess the viability of biological tissue". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0031/MQ63499.pdf.
Texto completoKoulaxouzidis, Andreas. "Application of fibre Bragg gratings for stress management in soft tissue biomechanics". Thesis, King's College London (University of London), 2001. https://kclpure.kcl.ac.uk/portal/en/theses/application-of-fibre-bragg-gratings-for-stress-management-in-soft-tissue-biomechanics(94093214-449c-4a35-a605-69e712f3d538).html.
Texto completoГусак, Євгенія Володимирівна, Евгения Владимировна Гусак, Yevheniia Volodymyrivna Husak, Ганна Олександрівна Яновська, Анна Александровна Яновская, Hanna Oleksandrivna Yanovska, Максим Володимирович Погорєлов, Максим Владимирович Погорелов, Maksym Volodymyrovych Pohorielov y Ye V. Kosik. "Тhe composite materials based on hydroxyapatite and gelatin for bone tissue application". Thesis, Sumy State University, 2017. http://essuir.sumdu.edu.ua/handle/123456789/64806.
Texto completoStone, N. "Raman spectroscopy of biological tissue for application in optical diagnosis of malignancy". Thesis, Department of Environmental and Ordnance Systems, 2009. http://hdl.handle.net/1826/4015.
Texto completoFan, Wei. "Physiological investigation of periosteum structure and its application in periosteum tissue engineering". Thesis, Queensland University of Technology, 2010. https://eprints.qut.edu.au/35722/7/35722b.pdf.
Texto completoIbrahim, Amel El-Kabashi Abdullah. "Application of morphometric analysis and tissue engineering to bioengineering personalised autologous bone tissues for the reconstruction of congenital midface deformities". Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/10037813/.
Texto completoGandhi, Milind Ramesh Ko Frank K. "Silk protein as a biomaterial for tissue engineering application: theoretical and experimental study /". Philadelphia, Pa. : Drexel University, 2006. http://hdl.handle.net/1860/1218.
Texto completoMcArthur, Paul. "Numerical analysis of open-ended coaxial line probes and its application to in-vivo dielectric measurements". Thesis, King's College London (University of London), 1989. https://kclpure.kcl.ac.uk/portal/en/theses/numerical-analysis-of-openended-coaxial-line-probes-and-its-application-to-invivo-dielectric-measurements(e5dde497-6cb0-4076-aa33-81890463d680).html.
Texto completoMcCrone, Michael Samuel. "The Effects of a Kinesio? Tape Application on Intramuscular Tissue Temperature Change during a 20-Minute Cryotherapy Application". Thesis, North Dakota State University, 2017. https://hdl.handle.net/10365/28591.
Texto completoBaeten, Kim Marieke. "Enhancement of single-chain urokinase activity by platelets". Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25495.
Texto completoBARI, ALESSANDRA. "Ion-containing mesoporous bioactive glass particles for tissue applications". Doctoral thesis, Politecnico di Torino, 2019. http://hdl.handle.net/11583/2753212.
Texto completoLittle, Uel. "Modification and optimisation of the biomaterial poly(epsilon-caprolactone) for tissue engineering application". Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491718.
Texto completoPartington, L. "Development of a pressurised transmural decellularisation method for application in tissue engineering trachea". Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1465826/.
Texto completoKreke, Michelle Renee. "Application of Fluid Flow for Functional Tissue Engineering of Bone Marrow Stromal Cells". Diss., Virginia Tech, 2005. http://hdl.handle.net/10919/27321.
Texto completoPh. D.
Vile, Douglas J. "Statistical modeling of interfractional tissue deformation and its application in radiation therapy planning". VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3675.
Texto completoLi, Cheng-Hsi y 李政昕. "Multipotent Stem Cells from Adipose Tissue :Application forPLGA 3D Scaffold in Skeletal Tissue Engineering". Thesis, 2002. http://ndltd.ncl.edu.tw/handle/uk45r8.
Texto completo國立成功大學
生物科技研究所碩博士班
90
Tissue engineering is a new field in biotechnology and has a powerful potential for tissue regeneration. Cell is a major component of tissue engineering, and stem cell with good differentiation capacity will be the most ideal source of cells. Human adipose tissue, obtained by suction-assisted lipectomy (i.e. liposuction), was processed to obtain a fibroblast-like population of cells named processed lipoaspirate (PLA cells) or adipose-derived stem cells(ADSCs). In this research, we were able to induce the differentiation of ADSCs into mesenchymal cell lineages, such as osteoblast, chrondrocyte, myocytes and adipocytes with the differentiation ratio of 81.62%, 41.33%, 1.75%, and 25.49%, respectively. In addition, we examined the attachment, growth and differentiation ability of ADSCs in porous PLGA (poly DL-lactic-co-glycolic acid). The result indicates that the proliferation & differentiation abilities of ADSCs cells is better in large pore size PLGA (300 ~ 500 um).
Tseng, Chen-Han y 曾琛涵. "Application of Decellularized Adipose Tissue/Silk Fibroin Matrix and Microspheres in Adipose Tissue Engineering". Thesis, 2013. http://ndltd.ncl.edu.tw/handle/47831236297898866830.
Texto completo國立臺灣大學
醫學工程學研究所
101
The soft tissue defects caused by congenital malformation, trauma, tumor removal and other various reasons affect the patient''s psychology and interpersonal relationship, so it has been gaining popularity for Plastic and Reconstructive Surgery. Due to advances in medicine, the emphasis on the requirements of the quality of medical care and physical appearance is increasing, and it also increases the demand for medical cosmetic. However, current challenge of adipose tissue engineering failed to maintain volume of adipose after transplantation, so it is important to find the soft fillers that have both functionality and aesthetics. In the study, we used decellularized porcine adipose matrix and silk fibroin as composite materials for scaffolds. The loss of the ECM content mixed in the scaffolds was slowed down by cross-linking. Eighty percentage collagen and thirty percentage GAG contents were retained after removing most cells and lipids from porcine adipose tissue. These bioactive contents have been proved to induce cell differentiation, and hydrolyzed silk fibroin also has the ability to promote cell proliferation. In addition, both of these materials have high biocompatibility, and they can increase the overall mechanical properties after blending. In vitro experiments, we observed that 3T3-L1 and adipose stem cells attached to the composite scaffolds successfully, and their GAG content increased 30 % to 45 % after culture several days, and there was remarkable difference between the composite scaffolds and the silk fibroin scaffolds. In vivo experiments, we observed that adipose matrix-silk fibroin composite microspheres were more effective to promote adipose stem cells proliferation and differentiation than silk fibroin microspheres. There are great potentials for the application of these hybrid materials in dermal fillers and soft tissue regeneration.
Xie, Baojun. "Colloidal gel and its application in tissue engineering". 2005. http://digital.library.okstate.edu/etd/umi-okstate-1572.pdf.
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