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1

Freitas, Tiago da Silva, Bernardo Assumpcao de Monaco y Stanley Golovac, eds. Neuromodulation Techniques for Pain Treatment. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-84778-4.

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2

Coben, Robert. Neurofeedback and neuromodulation techniques and applications. London: Academic, 2011.

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3

Boortz-Marx, Richard L., Daniel Moyse y Yawar J. Qadri. Intrathecal Pumps. Editado por Mehul J. Desai. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199350940.003.0031.

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Neuromodulation options that exist for chronic pain treatment include targeted intrathecal drug delivery, spinal cord stimulation, deep brain stimulation, cortical stimulation, and peripheral field stimulation. This chapter focuses on the neuromodulation technique of targeted intrathecal drug delivery. The chapter provides a brief overview of the history and focuses on clinically relevant discussion of patient selection, trialing, surgical technique, and other important topics for establishing a high-quality targeted intrathecal drug delivery program in this evolving age. The key to success with neuromodulation and targeted intrathecal drug delivery is patient selection. Appropriate pre-implantation screening and behavioral health assessment are critical. The choice of agent and route of delivery may play key roles in therapy success.
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4

Covert, Bryan y Marc A. Huntoon. Neuromodulation. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190217518.003.0010.

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This chapter addresses the indications for and complications related to surgical, pharmacologic, and adjunctive neuromodulation therapy. Many forms of neuromodulation therapy find their inspiration from the landmark work by Melzack and Wall in 1965 that described the gate theory of pain. Fifty years later, technological and pharmaceutical progress leads the charge on this exciting field within pain medicine. As understanding of the generation, transmission, and interpretation of pain signaling expands, the options for interventional and medical therapy will surely follow suit. These advancements are a welcome addition as the aging population meets a medical community seeking to curb chronic opioid therapy. The questions in this chapter serve as a guide to the salient neuromodulation techniques, but an emphasis should be placed on the suggested readings in this chapter to develop a more thorough understanding of the topic and variety of techniques and pharmacotherapy not covered.
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5

Neurofeedback and Neuromodulation Techniques and Applications. Elsevier, 2011. http://dx.doi.org/10.1016/c2009-0-64101-5.

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6

Coben, Robert. Neurofeedback and Neuromodulation Techniques and Applications. Elsevier Science & Technology, 2019.

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7

R, Evans James y Robert Coben. Neurofeedback and Neuromodulation Techniques and Applications. Elsevier Science & Technology Books, 2010.

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8

Coben, Robert y Kristy Snyder Colling. Neurofeedback and Neuromodulation Techniques and Applications. Elsevier Science & Technology Books, 2022.

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9

Todder, Doron, Keren Avirame y Hagit Cohen. Neuromodulation Methods in PTSD. Editado por Charles B. Nemeroff y Charles R. Marmar. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190259440.003.0039.

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This chapter discusses the rationale and methodology for applying techniques of active and passive neuromodulation for treatment-refractory post-traumatic stress disorder (PTSD). Neuromodulation derives from the concept of neuroplasticity, which signifies long-term changes in the effectiveness of connections between distinct parts of the central nervous system. These changes are reflected across multiple levels of the nervous system, going from the cellular level to circuits and large-scale brain networks. It has been long suggested that altered neuroplasticity is a biomarker of neuropsychiatric diseases. With recent advances in neuroscience, research is emerging on evaluating the potential of modulating neural circuits by using innovative technologies, including noninvasive and invasive brain stimulation, EEG-neurofeedback, and fMRI neurofeedback.
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10

Wassermann, Eric M. Direct current brain polarization. Editado por Charles M. Epstein, Eric M. Wassermann y Ulf Ziemann. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780198568926.013.0007.

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The transcranial application of weak direct current (DC) to the brain is an effective neuromodulation technique that has had more than a century of experimental and therapeutic use. Focal DC brain polarization is now undergoing renewed interest, because of the wide acceptance of TMS as a research tool and candidate treatment for brain disorders. The effects of static electrical fields on cortical neurons in vivo have been known since the advent of intracellular recording. These effects are highly selective for neurons oriented longitudinally in the plane of the electric field. DC can enhance cognitive processes occurring in the treated area. The earliest clinical application of DC polarization was in the field of mood disorders. However, due to lack of temporal and spatial resolution, this technique does not appear particularly useful for exploring neurophysiological mechanisms.
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11

Goodman, Wayne K. y Mark S. George. Neuromodulation and Psychiatric Disorders. Editado por Dennis S. Charney, Eric J. Nestler, Pamela Sklar y Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0010.

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An increasing number of approaches permit psychiatrists to directly stimulate the brain. Such therapies are sometimes referred to as neuromodulation, as psychiatrists can either excite or inhibit neuronal firing in the brain. This chapter reviews two such technologies—transcranial magnetic stimulation (TMS) and deep brain stimulation (DBS). Both techniques have FDA approval and are moving into mainstream therapeutic use. Daily prefrontal TMS for 4–6 weeks is FDA approved for treating depression, with minimal side effects. It is now accepted in most treatment algorithms as an approach for patients who have not responded to medications or talking therapy. DBS has virtually replaced ablative neurosurgery for use in medication-refractory movement disorders such as Parkinson’s Disease (PD), where it has the advantages of being reversible (explantable) and adjustable. DBS is now being studied in severe psychiatric conditions, such as intractable obsessive-compulsive disorder (OCD) and treatment resistant depression (TRD).
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12

Abd-Elsayed, Alaa. Neuromodulation Techniques for the Spine: A Volume in the Atlas of Interventional Pain Management Series. Elsevier, 2023.

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13

Glannon, Walter. Psychiatric Neuroethics II. Editado por John Z. Sadler, K. W. M. Fulford y Werdie (C W. ). van Staden. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780198732372.013.31.

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I discuss ethical issues relating to interventions other than intracranial surgery and psychopharmacology for psychiatric disorders. I question the distinction between “invasive” and “non-invasive” techniques applying electrical stimulation to the brain, arguing that this should be replaced by a distinction between more and less invasive techniques. I discuss electroconvulsive therapy (ECT); it can be a relatively safe and effective treatment for some patients with depression. I consider transcranial magnetic stimulation (TMS) and transcranial current stimulation (tCS); the classification of these techniques as non-invasive may lead to underestimation of their risks. I discuss how placebos can justifiably be prescribed non-deceptively and even deceptively in clinical settings. An analysis of neurofeedback as the neuromodulating technique most likely to promote autonomy/control for some conditions follows. Finally, I examine biomarkers identified through genetic screening and neuroimaging; they might contribute to more accurate prediction and diagnosis, more effective treatment, and possibly prevention of psychiatric disorders.
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14

Golovac, Stanley, Tiago da Silva Freitas y Bernardo Assumpcao de Monaco. Neuromodulation Techniques for Pain Treatment: A Step-By-Step Guide to Interventional Procedures and Managing Complications. Springer International Publishing AG, 2021.

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15

Golovac, Stanley, Tiago da Silva Freitas y Bernardo Assumpcao de Monaco. Neuromodulation Techniques for Pain Treatment: A Step-By-Step Guide to Interventional Procedures and Managing Complications. Springer International Publishing AG, 2022.

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16

Lo, Meng-chen, Marie-France Marin, Alik S. Widge y Mohammed R. Milad. Device-Based Treatment for PTSD. Editado por Frederick J. Stoddard, David M. Benedek, Mohammed R. Milad y Robert J. Ursano. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190457136.003.0025.

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Device-based neuromodulation is an emerging tool with great potential for significant scientific and clinical implications for a number of mental disorders. Neuromodulation techniques deliver electro-magnetic pulses into the brain via invasive or noninvasive electrodes, with various timing and stimulation parameters. The stimulation is thought to work as a “brain pacemaker” that either activates or inactivates targeted brain regions to restore normal homeostasis. There have been significant recent efforts to explore the clinical utility of device-based approaches for the treatment of mood, anxiety disorders, and to a limited extent posttraumatic stress disorder (PTSD). This chapter outlines the scientific underpinnings and rationale for various device-based treatments of PTSD, highlights positive results of studies in other mental disorders, and summarizes the limited clinical data related specifically to the treatment of PTSD and other trauma- and stressor-related disorders to date.
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17

Brunoni, Andre Russowsky, Bernardo de Sampaio Pereira Júnior y Izio Klein. Neuromodulatory approaches for bipolar disorder: current evidences and future perspectives. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0028.

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Bipolar disorder is a prevalent condition, with few therapeutic options and a high degree of refractoriness. This justifies the development of novel non-pharmacological treatment strategies, such as the non-invasive techniques of transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), as well as the invasive techniques of deep brain stimulation (DBS) and vagus nerve stimulation (VNS). In this chapter, we provide a summary of the development of the techniques as well as the studies carried out with patients with bipolar disorder. Although many promising results regarding the efficacy of theses techniques were described, the total number of studies is still low, highlighting the need of further studies in larger samples as to provide a definite picture regarding the use of clinical neuromodulation in bipolar disorder.
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18

Shils, Jay L., Sepehr Sani, Ryan Kochanski, Mena Kerolus y Jeffrey E. Arle. Recording Techniques Related to Deep Brain Stimulation for Movement Disorders and Responsive Stimulation for Epilepsy. Editado por Donald L. Schomer y Fernando H. Lopes da Silva. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190228484.003.0038.

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Neuromodulation therapies are now common treatments for a variety of medically refractory disorders, including movement disorders and epilepsy. While surgical techniques for each disorder vary, electricity is used by both for relieving symptoms. During stereotactic placement of the stimulating electrode, either deep brain stimulation electrodes or cortical strip electrodes, intraoperative neurophysiology is used to localize the target structure. This physiology includes single-unit recordings, neurostimulation evoked response evaluation, and intracranial electroencephalography (EEG) to ensure the electrode leads are in the optimal location. Because the functional target for the responsive neurostimulator is more easily visualized on preoperative magnetic resonance imaging, intraoperative physiology is used more as a confirmatory tool, in contrast to the more functional localization-based use during electrode placement for movement disorders. This chapter discusses surgical placement of the electrodes for each procedure and the physiological guidance methodology used to place the leads in the optimal location.
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19

Candido, Kenneth D., Teresa M. Kusper y Nebojsa Nick Knezevic. Chronic Chest Wall Pain in Postherpetic Neuralgia. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0014.

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Postherpetic neuralgia (PHN) is a debilitating condition that frequently arises after herpes zoster (HZ) caused by the varicella-zoster virus. It is characterized by severe neuropathic pain and sensory disturbances persisting after the resolution of characteristic vesicular skin lesions. Most commonly affected are the thoracic dermatomes. Trigeminal (V1), cervical, and lumbar nerves are other frequently affected sites. Early treatment shortens the duration of acute HZ and may prevent the onset of PHN. A variety of modalities are utilized to treat PHN, including chemical compounds, interventional pain techniques, and neuromodulation. HZ vaccine is recommended for individuals more than 60 years old, and it is currently the best method of averting HZ and consequent progression to PHN.
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