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Literatura académica sobre el tema "Technique de neuromodulation"

Autor: Grafiati

Publicado: 25 de mayo de 2024

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Artículos de revistas sobre el tema "Technique de neuromodulation"

Yamamoto, Takamitsu. "Functional Neurosurgery with Neuromodulation Technique". Journal of Nihon University Medical Association 76, n.º 1 (2017): 40–44. http://dx.doi.org/10.4264/numa.76.1_40.

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Abejón, David y Enrique Reig. "Is Pulsed Radiofrequency a Neuromodulation Technique?" Neuromodulation: Technology at the Neural Interface 6, n.º 1 (enero de 2003): 1–3. http://dx.doi.org/10.1046/j.1525-1403.2003.03009.x.

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Matzel, Klaus E., Emmanuel Chartier-Kastler, Charles H. Knowles, Paul A. Lehur, Arantxa Muñoz-Duyos, Carlo Ratto, Mona B. Rydningen, Michael Sørensen, Philip van Kerrebroeck y Stefan de Wachter. "Sacral Neuromodulation: Standardized Electrode Placement Technique". Neuromodulation: Technology at the Neural Interface 20, n.º 8 (4 de octubre de 2017): 816–24. http://dx.doi.org/10.1111/ner.12695.

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Ratto, Carlo, Umberto Morelli, Stefania Paparo, Angelo Parello y Giovanni Battista Doglietto. "Minimally Invasive Sacral Neuromodulation Implant Technique". Diseases of the Colon & Rectum 46, n.º 3 (marzo de 2003): 414–17. http://dx.doi.org/10.1007/s10350-004-6565-6.

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Reffat, Noora, Carolina Pusec, Scott Price, Mayank Gupta, Philippe Mavrocordatos y Alaa Abd Elsayed. "Neuromodulation Techniques for Headache Management". Life 14, n.º 2 (24 de enero de 2024): 173. http://dx.doi.org/10.3390/life14020173.

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This narrative review aims to summarize evidence regarding the current utilization and future applications of neuromodulation in patients with headaches, with special attention paid to migraine and chronic cluster headache. A search was conducted in PubMed in August of 2023 to survey the current literature on neuromodulation for the treatment of headache. In total, the search yielded 1989 results, which were further filtered to include only systematic reviews published between 2022 to 2023 to capture the most up-to-date and comprehensive research on this topic. The citation lists of these articles were reviewed to find additional research on neuromodulation and supplement the results presented in this paper with primary literature. Research on the use of neuromodulation for the treatment of headache has predominantly focused on four neuromodulation techniques: peripheral nerve stimulation (PNS), transcranial magnetic stimulation (TMS), deep brain stimulation (DBS), and spinal cord stimulation (SCS). Outcome measures reported in this article include impact on migraine and headache frequency and/or pain intensity, adverse effects of the neuromodulation technique, and associated costs, when available. We found that neuromodulation has developed utility as an alternative treatment for both chronic cluster headaches and migraines, with a reduction in frequency and intensity of headache most elucidated from the articles mentioned in this review.

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Shirane, Risako, Eonjung Kim, Daniela Riveros y Huma Sheikh. "Neuromodulation for Prevention and Treatment of Headache Disorders". US Neurology 18, n.º 2 (2022): 103. http://dx.doi.org/10.17925/usn.2022.18.2.103.

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Neuromodulation is a treatment modality that can be used in the abortive and preventive treatment of migraine and other primary headache disorders. The basic concept of neurostimulation is to manipulate peripheral or central pain pathways with either magnetic or electrical impulses. Common neuromodulation techniques include occipital nerve stimulation, which is the oldest technique, and trigeminal nerve stimulation, combined occipital and trigeminal nerve stimulation, sphenopalatine ganglion stimulation, vagus nerve stimulation and transcranial magnetic stimulation, which were introduced soon after. The two newest modalities are remote electrical neuromodulation and caloric vestibular stimulation, the last of which is still in the experimental phases.

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Ammirati, Enrico, Alessandro Giammò, Alberto Manassero y Roberto Carone. "Neuromodulation in urology, state of the art". Urologia Journal 86, n.º 4 (1 de agosto de 2019): 177–82. http://dx.doi.org/10.1177/0391560319866075.

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Sacral neuromodulation is an approved and validated treatment for overactive bladder syndrome, chronic non-obstructive retention, and chronic pelvic pain. Percutaneous tibial nerve stimulation is a less invasive approach of neuromodulation. We performed a literature research to assess the current evidence available about neuromodulation. Both techniques appear to be effective and safe third-line treatments. The overall success rate ranges from 43% to 85% for sacral neuromodulation and from 40% to 79.5% for percutaneous tibial nerve stimulation. Sacral neuromodulation has a higher incidence of complications in comparison to percutaneous tibial nerve stimulation, due to the more invasive surgical technique and the presence of a permanent implant. The incidence of surgical revision ranges between 9% and 33%. The most frequent complication with sacral neuromodulation is pain at implant site (15%–42%), followed by lead migration (4%–21%), pain at lead site (5.4%–19.1%), leg pain (18%), and infection (5.7%–6.1%). The quality of the studies on sacral neuromodulation and percutaneous tibial nerve stimulation in literature is quite modest, because of the shortage of good randomized clinical trial; most of the studies are prospective observational studies with mid-term follow-up.

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Hoang Roberts, L., C. Shenhar, J. Booher, L. Gleich, K. Peters y M. Tracy Bee. "NOVEL PUDENDAL NEUROMODULATION TECHNIQUE USING ANATOMICAL LANDMARKS". Continence 7 (septiembre de 2023): 100763. http://dx.doi.org/10.1016/j.cont.2023.100763.

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Tuccitto, G., L. Maccatrozzo, M. Mangano, P. Checchin y G. Anselmo. "Neuromodulation: A new frontier?" Urologia Journal 64, n.º 1 (febrero de 1997): 119–22. http://dx.doi.org/10.1177/039156039706400129.

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It is often impossible to identify the precise cause of urethrocystalgia at radiological and functional confirmation of diagnosis and therapy is therefore frequently symptomatic without resolving the underlying cause. Neuromodulation by stimulating the sacral nerves of the vertebral foramina has recently been introduced into clinical practice. At present only a few specialised centres have implemented this therapy as second choice in treating lower urinary tract dysfunction secondary to detrusorial hyper- or hypoactivity and pelvic pain. The authors review literature on the subject and report on the multi-centre experience of Brescia, Padua and Treviso in treating urethrocystalgias. A method has been used that is by now standardised with regard to temporary percutaneous stimulation techniques and final implant. Ways of correctly identifying predictive factors which would indicate suitability for application of the method are, however, still unclear. It is to be hoped that studies involving larger numbers of cases may provide the answers, so that specialists can apply the technique more correctly.

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Moscovich, Mariana, Camila Henriques de Aquino, Murilo Martinez Marinho, Lorena Broseghini Barcelos, André C. Felício, Matthew Halverson, Clement Hamani, Henrique Ballalai Ferraz y Renato Puppi Munhoz. "Fundamentals of deep brain stimulation for Parkinson's disease in clinical practice: part 2". Arquivos de Neuro-Psiquiatria 82, n.º 04 (abril de 2024): 001–9. http://dx.doi.org/10.1055/s-0044-1786037.

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AbstractThe field of neuromodulation has evolved significantly over the past decade. Developments include novel indications and innovations of hardware, software, and stimulation techniques leading to an expansion in scope and role of these techniques as powerful therapeutic interventions. In this review, which is the second part of an effort to document and integrate the basic fundamentals and recent successful developments in the field, we will focus on classic paradigms for electrode placement as well as new exploratory targets, mechanisms of neuromodulation using this technique and new developments, including focused ultrasound driven ablative procedures.

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Tesis sobre el tema "Technique de neuromodulation"

Thomasset, Laure. "La neuroéthique saisie par le droit : contribution à l'élaboration d'un droit des neurotechnologies". Electronic Thesis or Diss., Paris 1, 2021. https://buadistant.univ-angers.fr/login?url=https://bibliotheque.lefebvre-dalloz.fr/secure/isbn/9782247226603.

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Née dans les années 2000 pour répondre à une inquiétude éthique grandissante provoquée par les avancées neuroscientifiques, la neuroéthique s’entend comme une réflexion éthique spécifique aux neurosciences. Saisie par le droit depuis la loi de bioéthique du 7 juillet 2011, elle a intégré la sphère juridique sous la forme d 'un régime spécial : le droit des neurotechnologies. Parce que celui-ci relève indéniablement du droit de la bioéthique, la prise en compte du risque sanitaire générée par ces technologies a été une évidence. A l’examen pourtant, la justification de la création de règles spécifiques pour les techniques neuroscientifiques réside d’abord et avant tout dans la présence d’un risque d’une autre nature : le risque comportemental. Curieusement, celui-ci n’a été que peu pris en considération dans ses différents aspects par le législateur. Partant de ce constat, l'objet de cette thèse est d’apporter une contribution à l’élaboration de ce régime spécial, en tentant d’intégrer davantage les enjeux du risque comportemental dans le corps des règles juridiques, sans que l’attention portée au risque sanitaire en souffre par la même occasion. En ce sens, les mesures sont proposées pour chaque famille de neurotechnologies. Concernant les techniques d’imagerie cérébrale, il s’agit de restreindre les finalités autorisées et de corriger les modalités du consentement. Concernant les techniques de neuromodulation, il s’agir de limiter les finalités d’utilisation et de réaménager les règles de la responsabilité
Born in the 2000s with the aim of addressing a growing ethical concern over the neuroscientist advances, neuroethics shall be understood as an ethical reflection related to neurosciences. Seized by law since the law on bioethics dated July, 7th 2011, it was embedded in the legal sphere by means of a special regime, namely neurotechnology law. Since the latter undeniably fails within bioethics law, the health risk arising from these technologies was self-evidently considered. After scrutiny though, the rationale behind creating rules peculiar to neuroscientist technologies mainly lies in the presence of a different risk : the behavioural risk. Surprisingly, such risk was given cursory consideration only in its various aspects by the legislature. Based on this observation, the purpose of this thesis is to make a contribution to the development of the aforementioned special regime, by seeking to integrate further the behavioural risk issues without detriment to the consideration already given to the health risk. Towards that end, measures are proposed for each family of neurotechnologics. As regards cerebral imaging technologies, this includes restricting their permissible purposes as well as correcting the conditions for prior consent. With respect, to neuromodulation technologies, it is a question, of limiting their purpose for use and to overhaul the liability rules

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Hadar, Ravit [Verfasser]. "Using the maternal immune stimulation model of schizophrenia to investigate the therapeutic efficacy of neuromodulation techniques / Ravit Hadar". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2020. http://d-nb.info/1211344215/34.

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Thomas, Sarah Helen. "A BRAIN-COMPUTER INTERFACE FOR CLOSED-LOOP SENSORY STIMULATION DURING MOTOR TRAINING IN PATIENTS WITH TETRAPLEGIA". UKnowledge, 2019. https://uknowledge.uky.edu/cbme_etds/56.

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Normal movement execution requires proper coupling of motor and sensory activation. An increasing body of literature supports the idea that incorporation of sensory stimulation into motor rehabilitation practices increases its effectiveness. Paired associative stimulation (PAS) studies, in which afferent and efferent pathways are activated in tandem, have brought attention to the importance of well-timed stimulation rather than non-associative (i.e., open-loop) activation. In patients with tetraplegia resulting from spinal cord injury (SCI), varying degrees of upper limb function may remain and could be harnessed for rehabilitation. Incorporating associative sensory stimulation coupled with self-paced motor training would be a means for supplementing sensory deficits and improving functional outcomes. In a motor rehabilitation setting, it seems plausible that sensory feedback stimulation in response to volitional movement execution (to the extent possible), which is not utilized in most PAS protocols, would produce greater benefits. This capability is developed and tested in the present study by implementing a brain-computer interface (BCI) to apply sensory stimulation synchronized with movement execution through the detection of movement intent in real time from electroencephalography (EEG). The results demonstrate that accurate sensory stimulation application in response to movement intent is feasible in SCI patients with chronic motor deficit and often precedes the onset of movement, which is deemed optimal by PAS investigations that do not involve a volitional movement task.

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Tsao, Tzu-Hsin B. "From molecular pathways to neural populations: investigations of different levels of networks in the transverse slice respiratory neural circuitry". Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/37296.

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By exploiting the concept of emergent network properties and the hierarchical nature of networks, we have constructed several levels of models facilitating the investigations of issues in the area of respiratory neural control. The first of such models is an intracellular second messenger pathway model, which has been shown to be an important contributor to intracellular calcium metabolism and mediate responses to neuromodulators such as serotonin. At the next level, we have constructed new single neuron models of respiratory-related neurons (e.g. the pre-Btzinger complex neuron and the Hypoglossal motoneuron), where the electrical activities of the neurons are linked to intracellular mechanisms responsible for chemical homeostasis. Beyond the level of individual neurons, we have constructed models of neuron populations where the effects of different component neurons, varying strengths and types of inter-neuron couplings, as well as network topology are investigated. Our results from these simulation studies at different structural levels are in line with experiment observations. The small-world topology, as observed in previous anatomical studies, has been shown here to support rhythm generation along with a variety of other network-level phenomena. The interactions between different inter-neuron coupling types simultaneously manifesting at time-scales orders of magnitude apart suggest possible explanations for variations in the outputs measured from the XII rootlet in experiments. In addition, we have demonstrated the significance of pacemakers, along with the importance of considering neuromodulations and second-messenger pathways in an attempt to understand important physiological functions such as breathing activities.

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Libros sobre el tema "Technique de neuromodulation"

Freitas, Tiago da Silva, Bernardo Assumpcao de Monaco y Stanley Golovac, eds. Neuromodulation Techniques for Pain Treatment. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-84778-4.

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Coben, Robert. Neurofeedback and neuromodulation techniques and applications. London: Academic, 2011.

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Boortz-Marx, Richard L., Daniel Moyse y Yawar J. Qadri. Intrathecal Pumps. Editado por Mehul J. Desai. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199350940.003.0031.

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Neuromodulation options that exist for chronic pain treatment include targeted intrathecal drug delivery, spinal cord stimulation, deep brain stimulation, cortical stimulation, and peripheral field stimulation. This chapter focuses on the neuromodulation technique of targeted intrathecal drug delivery. The chapter provides a brief overview of the history and focuses on clinically relevant discussion of patient selection, trialing, surgical technique, and other important topics for establishing a high-quality targeted intrathecal drug delivery program in this evolving age. The key to success with neuromodulation and targeted intrathecal drug delivery is patient selection. Appropriate pre-implantation screening and behavioral health assessment are critical. The choice of agent and route of delivery may play key roles in therapy success.

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Covert, Bryan y Marc A. Huntoon. Neuromodulation. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190217518.003.0010.

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This chapter addresses the indications for and complications related to surgical, pharmacologic, and adjunctive neuromodulation therapy. Many forms of neuromodulation therapy find their inspiration from the landmark work by Melzack and Wall in 1965 that described the gate theory of pain. Fifty years later, technological and pharmaceutical progress leads the charge on this exciting field within pain medicine. As understanding of the generation, transmission, and interpretation of pain signaling expands, the options for interventional and medical therapy will surely follow suit. These advancements are a welcome addition as the aging population meets a medical community seeking to curb chronic opioid therapy. The questions in this chapter serve as a guide to the salient neuromodulation techniques, but an emphasis should be placed on the suggested readings in this chapter to develop a more thorough understanding of the topic and variety of techniques and pharmacotherapy not covered.

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Neurofeedback and Neuromodulation Techniques and Applications. Elsevier, 2011. http://dx.doi.org/10.1016/c2009-0-64101-5.

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Coben, Robert. Neurofeedback and Neuromodulation Techniques and Applications. Elsevier Science & Technology, 2019.

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R, Evans James y Robert Coben. Neurofeedback and Neuromodulation Techniques and Applications. Elsevier Science & Technology Books, 2010.

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Coben, Robert y Kristy Snyder Colling. Neurofeedback and Neuromodulation Techniques and Applications. Elsevier Science & Technology Books, 2022.

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Todder, Doron, Keren Avirame y Hagit Cohen. Neuromodulation Methods in PTSD. Editado por Charles B. Nemeroff y Charles R. Marmar. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190259440.003.0039.

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This chapter discusses the rationale and methodology for applying techniques of active and passive neuromodulation for treatment-refractory post-traumatic stress disorder (PTSD). Neuromodulation derives from the concept of neuroplasticity, which signifies long-term changes in the effectiveness of connections between distinct parts of the central nervous system. These changes are reflected across multiple levels of the nervous system, going from the cellular level to circuits and large-scale brain networks. It has been long suggested that altered neuroplasticity is a biomarker of neuropsychiatric diseases. With recent advances in neuroscience, research is emerging on evaluating the potential of modulating neural circuits by using innovative technologies, including noninvasive and invasive brain stimulation, EEG-neurofeedback, and fMRI neurofeedback.

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Wassermann, Eric M. Direct current brain polarization. Editado por Charles M. Epstein, Eric M. Wassermann y Ulf Ziemann. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780198568926.013.0007.

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The transcranial application of weak direct current (DC) to the brain is an effective neuromodulation technique that has had more than a century of experimental and therapeutic use. Focal DC brain polarization is now undergoing renewed interest, because of the wide acceptance of TMS as a research tool and candidate treatment for brain disorders. The effects of static electrical fields on cortical neurons in vivo have been known since the advent of intracellular recording. These effects are highly selective for neurons oriented longitudinally in the plane of the electric field. DC can enhance cognitive processes occurring in the treated area. The earliest clinical application of DC polarization was in the field of mood disorders. However, due to lack of temporal and spatial resolution, this technique does not appear particularly useful for exploring neurophysiological mechanisms.

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Capítulos de libros sobre el tema "Technique de neuromodulation"

Assis, Fabricio, Charles Amaral y João Henrique Araújo. "Spinal Cord Stimulation: Percutaneous Technique". En Neuromodulation Techniques for Pain Treatment, 23–41. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_2.

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Benzecry Almeida, Daniel. "Spinal Cord Stimulation: Surgical (Paddle) Technique". En Neuromodulation Techniques for Pain Treatment, 43–61. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_3.

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Barbosa de Oliveira, Antônio Jorge, Plinio Duarte Mendes, Gilberto de Almeida Fonseca Filho y Fabian C. Piedimonte. "Intrathecal Drug Delivery System: Surgical Technique". En Neuromodulation Techniques for Pain Treatment, 245–71. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_17.

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Assumpcao de Monaco, Bernardo y Joacir Graciolli Cordeiro. "Intracerebroventricular Drug Infusion System Implant: Surgical Technique". En Neuromodulation Techniques for Pain Treatment, 273–80. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_18.

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Nouer, Thiago Frederico y Tiago da Silva Freitas. "Brachial Plexus Stimulation Using Ultrasound: New Technique Description". En Neuromodulation Techniques for Pain Treatment, 131–40. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_10.

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Hamani, Clement. "Deep Brain Stimulation for Pain: Indications and Technique". En Neuromodulation Techniques for Pain Treatment, 73–80. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_5.

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Freitas, Tiago da Silva. "Occipital Nerve Stimulation Using an Ultrasound Surgical Technique". En Neuromodulation Techniques for Pain Treatment, 141–50. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_11.

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Freitas, Tiago da Silva. "Peripheral Nerve Stimulation Technique Using Ultrasound in Lower Limbs". En Neuromodulation Techniques for Pain Treatment, 173–97. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_13.

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Freitas, Tiago da Silva. "Peripheral Nerve Stimulation in Upper Limb Using Ultrasound Technique". En Neuromodulation Techniques for Pain Treatment, 151–71. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_12.

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Dantas, Sérgio Adrian Fernandes, Francisco Irochima Pinheiro y César Araújo Britto. "Sacral Neuromodulation for Urinary and Fecal Incontinence: Surgical Technique". En Neuromodulation Techniques for Pain Treatment, 297–303. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84778-4_21.

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Actas de conferencias sobre el tema "Technique de neuromodulation"

Shandybina, N., S. Ananyev, А. Aliev, I. Shalmiev, S. Kozureva, M. Averkiev, V. Bulanov et al. "On the effectiveness of integration of a rehabilitation device based on a neurointerface and neurostimulation of the spinal cord in the rehabilitation of patients with impaired upper limb movement due to neurological disorders". En VIII Vserossijskaja konferencija s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka». Publishing center of Ulyanovsk State University, 2021. http://dx.doi.org/10.34014/mpphe.2021-217-221.

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Millions of people around the world suffer from disorders caused by injuries and diseases of the brain and spinal cord. The combination of brain-computer interfaces and neuromodulation technologies is a new approach that could revolutionize the treatment of these disorders. In this study, we tested the effectiveness of a technique in which a patient with a spinal cord injury first undergoes spinal cord stimulation and then participates in a rehabilitation session using a brain-computer interface based on the P300 principle, which decodes visual-motor transformation and uses an assistive robot that moves the patient’s arm, and virtual reality. All healthy participants of the study were able to combine these two techniques without any undesirable effects; studies on patients with spinal cord injury are ongoing. System integration of the two methods has been already performed, and in the future, upon completion of this work, the neural interface will be able to control the stimulation parameters. We propose such integrated systems as a new approach to neurorehabilitation. Key words: brain-computer interface, neuromodulation, spinal cord stimulation, spinal cord trauma, P300, visuomotor transformation.

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Souza, Felipe dos Santos, Matheus Furlan Chaves y Guilherme da Cunha Messias dos Santos. "Rhodopsin stimulation in neural circuits by neuromodulation in optogenetics: current findings on the use of Deep Brain Stimulation (DBS)". En XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.302.

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Introduction: Optogenetic neuromodulation describes a contemporary technique of brain modulation that has been increasingly studied, both in the field of genetic engineering and in neuroscience, for the treatment of diseases such as epilepsy, schizophrenia, parkinson and essential tremor. Through it, we seek to alter neurons, making them sensitive to light stimulation. For this, viral vectors are used to insert opsin genes into neural tissue. Objective: to describe the most recent scientific findings related to the use of DBS using Optogenetics techniques. Methodology: use of databases, SCIELO, PUBMED, LILACS and American Association of Neurological Surgeons using the following descriptors: Genetic Engineering. Deep Brain Stimulation. Optogenetics. Rhodopsins. Results: The use and Deep Brain Stimulantion (DBS) or Pronfunda Cerebral Stimulation (ECP) for therapeutic intervention in patients with movement disorders is performed through the insertion of a tungsten wire in specific areas of the central nervous system with the passage of electric current from microampers for milliseconds. However, over time, this causes plasticity, associated with gliosis and loss of DBS effectiveness. In addition, scientific evidence shows that cerebral neuromodulation by optogenetics in patients with dystonia, depression and obsessive compulsive disorder (OCD) is also already a reality with significant and approved results. Conclusions: Optognetics can replace classic DBS for the treatment of several neurological comorbidities with safety and space-time precision, with minimal side effects, when compared with that technique.

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Wang, Yi, Yen Yu Ian Shih y Yuan-shin Lee. "Vibration-Assisted Insertion of Flexible Neural Microelectrodes With Bio-Dissolvable Guides for Medical Implantation". En ASME 2021 16th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/msec2021-63952.

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Abstract This paper presents vibration-assisted insertion of flexible neural electrodes with bio-dissolvable guides to deliver accurate microprobe insertion with minimized tissue damage. Invasive flexible neural microprobe is an important new tool for neuromodulation and recording research for medical neurology treatment applications. Flexible neural electrode probes are susceptible to bending and buckling during surgical implantation due to the thin and flexible soft substrates. Inspired by insects in nature, a vibration-assisted insertion technique is developed for flexible neural electrode insertion to deliver accurate microprobe insertion with minimized tissue damage. A three-dimensional combined longitudinal-twisting (L&T) vibration is used to reduce the insertion friction force, and thus reducing soft tissue damage. To reduce the flexible microelectrode buckling during surgical insertion, a bio-dissolvable Polyethylene glycol (PEG) guide is developed for the enhancement of flexible neural probe stiffness. Combining these two methods, the insertion performance of the flexible neural probe is significantly improved. Both the in vitro and the in vivo experiments were conducted to validate the proposed techniques.

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Loreti, Eduardo Henrique, Giovanna Fernandes dos Reis, Alisson Alexandre da Silva y Marcelo Gonçalves da Silva. "Is non-invasive neuromodulation effective in the treatment of gestational depression? A systematic review with bibliometric analysis". En XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.332.

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Background: The gestational period is a period of high prevalence of mental disorders, including depression, requiring effective therapeutic measures. Objectives: systematize the effects of Transcranial Direct Current Stimulation (tDCS) and Transcranial Magnetic Stimulation (TMS) in the treatment of depression during pregnancy. Design and setting: Systematic review with bibliometric. Methods: Articles were searched in the databases: MEDLINE/PubMed, Web of Science and Scopus. Randomized clinical trials, case-control studies and case series, published between 2011 and 2020, that used tDCS and TMS to treat depression in pregnant patients were included. Studies that used transcranial electrostimulation associated with another technique (except the pharmacological one) were excluded. The quality of studies was evaluated independently by the reviewers according to the Cochrane Handbook for Systematic Reviews for Interventions for assessing bias. Software R was used to perform bibliometrics. Results: Seven studies were included, totaling 102 participants. The stimulated area was the dorsalateral prefrontal cortex (CPFDL). Two studies used tDCS with an intensity of 2 mA and application for 20 minutes and 30 minutes. Five studies used TMS, of which 2 used a frequency of 1 Hz, 2 used 25 Hz and 1 used 10 Hz. The University of Pennsylvania sets up the research center with the most affiliated articles, 8 in total. The author with the greatest impact was Kin, D.R. (index h: 6, index g: 7, index m: 0.462, total of publications 7, beginning: 2009). Conclusions: tDCS and TMS proved to be effective for the treatment of symptoms of depression during pregnancy. Systematic Review Registration: The review was registered in PROSPERO with protocol: CRD42021235355.

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Teimoori, Khashayar, Ali M. Sadegh y Bhaskar Paneri. "Novel Electro-FSI Model of Trabecular Network in the Brain Sub Arachnoid Space". En ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-10529.

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Abstract The brain is encased in the skull and suspended and supported by a series of three fibrous tissue layers: Dura mater, Arachnoid and Pia matter, known as the Meninges. Arachnoid trabeculae are strands of collagen tissues located in a space between the arachnoid and the pia matter known as the subarachnoid space (SAS). The SAS trabeculae play an important role in damping and reducing the relative movement of the brain with respect to the skull. The SAS is filled with cerebrospinal fluid (CSF), which is a colorless fluid that surrounds all over the brain inside the subarachnoid spaces. This fluid stabilizes the shape and position of the brain during head movements. To address normal and pathological SAS functions, under conditions where an electrical stimulation is applied, this study proposes a novel fully-coupled electro-Fluid-Structure Interaction (eFSI) modeling approach to investigate the response of the system of SAS-CSF under the applied electric current, which is provided by the transcranial Direct Current Stimulation (tDCS) technique according to the following steps. First, a two-dimensional channel model of the brain SAS with several trabecular morphologies is numerically simulated using the finite element (FE) method. The channel model is then subjected to a specific electric field intensity by applying a 1∼2mA direct current. COMSOL Multiphysics v. 5.3a software is used to perform the coupled eFSI numerical simulation in order to investigate the effects of the applied electric field on the flow of the CSF, thereby showing the deflection of the trabeculae inside the channel model. The results of this study demonstrate that the induced electric field causes less deflection of the trabeculae by exacerbating the velocity profile of the cerebrospinal fluid flow and decreasing the flow pressure applied on each trabecula inside the trabecular SAS channel. This electro-mechanostructural modeling approach is significant because of the applied current on the channel walls that can directly affect the CSF flow. In fact, the results of this study can open up a new horizon for future research on disorders like hydrocephalus, which involves an unusual production rate of the CSF inside the brain. This disorder may be controlled by applying an electric current in the brain, using one of the available brain stimulation techniques, i.e. tDCS. By using an electrical stimulation technique, one might control the dynamics of brain function and, therefore, regulate dysfunctionality through the first eFSI multiphysics modeling approach proposed in this study. Briefly, the brain SAS may be considered as a novel region for electrotherapeutic and electromechanical neuromodulation.

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Bernardo, Juliana Matos Ferreira, Artur Bruno Silva Gomes, Felipe Jatobá Leite Nonato de Sá, Júlia Gonçalves Ferreira y Maria Rosa da Silva. "Phantom pain: pathophysiology and therapeutic approaches". En XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.496.

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Background: Phantom pain is a mentally debilitating neuropathy that affects post-amputees. It interferes with the independence and performance of activities, therefore affecting the quality of life. Its pathophysiology ranges from lesions in peripheral innervations, to spinal functional changes, modulation of cortical circuits and psychological factors Objectives : Demonstrate new therapeutic approaches and establish a relation with the pathophysiological mechanisms. Methods: Integrative review applying the descriptors: “phantom pain”, “physiopathology”, “post amputation pain”, “treatment”, and the Boolean operator AND. The searches were carried out at PUBMED with 142 results, at BVS with 113, and at Scielo ,showing no results. At the end, 9 papers were selected. No linguistic filters were used and articles published between 2016 and May 2020 were incorporated. Results: (1) Motor images, mental and visual representation of the limb and its function; (2) peripheral interfaces enables prosthetic control; both techniques active cortical reorganization by promoting sensory feedback to motor stimuli. (3) repetitive transcranial magnetic stimulation and (4) direct current, a non-invasive approach, for maladaptive cortical neuromodulation, in addition to stimulate peripheral innervation. In surgical interventions, (5) targeted muscle reinnervation is used in the residual nerves on amputation process to reinnervate the motor terminal of the remaining muscles, promoting nerve growth and organization. Conclusions Physiological investigation applied to treatments enables effective therapeutics, anticipating rehabilitation. The representation of images, peripheral interfaces, brain stimulation and less invasive surgical techniques.

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Informes sobre el tema "Technique de neuromodulation"

chen, sulian y juan huai. Non-invasive brain neuromodulation techniques for phantom limb pain: a systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, noviembre de 2023. http://dx.doi.org/10.37766/inplasy2023.11.0032.

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