Bibliografías temáticas / Synthesis design / Artículos de revistas

Artículos de revistas sobre el tema "Synthesis design"

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Publicado: 11 de marzo de 2023

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1

Marshall, William J. "Transducer design synthesis." Journal of the Acoustical Society of America 129, n.º 4 (abril de 2011): 2578. http://dx.doi.org/10.1121/1.3588513.

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2

Campbell, Matthew I. y Kristina Shea. "Computational design synthesis". Artificial Intelligence for Engineering Design, Analysis and Manufacturing 28, n.º 3 (22 de julio de 2014): 207–8. http://dx.doi.org/10.1017/s0890060414000171.

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3

Chelimsky, Eleanor, George Silberman y Judith Droitcour. "Cross design synthesis". Lancet 341, n.º 8843 (febrero de 1993): 498. http://dx.doi.org/10.1016/0140-6736(93)90253-d.

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4

Cen Xiang, Cen Xiang, Xiangshun Kong Xiangshun Kong, Feng Gao Feng Gao, Yufan Zhao Yufan Zhao, Jiang Liu Jiang Liu y Yuan Yuan and Yuou Teng Yuan Yuan and Yuou Teng. "Design, Synthesis and Antioxidant Activity of Chalcone Derivative CMZ-3-5". Journal of the chemical society of pakistan 43, n.º 5 (2021): 598. http://dx.doi.org/10.52568/000600/jcsp/43.05.2021.

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Excessive accumulation of free radicals can cause a variety of diseases. According to reports, chalcone has the activity of scavenging free radicals. In this study, we synthesized a chalcone derivative CZM-3-5 and evaluated its antioxidant activity using a chemical assessment method (2,2and#39;-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS•+) assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH•) assay and total reducing antioxidant power (FRAP) assay) and a cell model of oxidative damage induced by hydrogen peroxide (H2O2). The chemical evaluation results show that the compound CZM-3-5 has good antioxidant capacity and free radical scavenging ability. MTT analysis showed that the compound has cytoprotective activity in H2O2-induced PC12 cells, and the mechanism may be related to the cytoprotective substance superoxide dismutase (SOD) is related to the level of glutathione (GSH). Overall, our findings indicate that compound CZM-3-5 has potential antioxidant activity in vitro.
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5

Cen Xiang, Cen Xiang, Xiangshun Kong Xiangshun Kong, Feng Gao Feng Gao, Yufan Zhao Yufan Zhao, Jiang Liu Jiang Liu y Yuan Yuan and Yuou Teng Yuan Yuan and Yuou Teng. "Design, Synthesis and Antioxidant Activity of Chalcone Derivative CMZ-3-5". Journal of the chemical society of pakistan 43, n.º 5 (2021): 598. http://dx.doi.org/10.52568/000600.

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Excessive accumulation of free radicals can cause a variety of diseases. According to reports, chalcone has the activity of scavenging free radicals. In this study, we synthesized a chalcone derivative CZM-3-5 and evaluated its antioxidant activity using a chemical assessment method (2,2and#39;-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS•+) assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH•) assay and total reducing antioxidant power (FRAP) assay) and a cell model of oxidative damage induced by hydrogen peroxide (H2O2). The chemical evaluation results show that the compound CZM-3-5 has good antioxidant capacity and free radical scavenging ability. MTT analysis showed that the compound has cytoprotective activity in H2O2-induced PC12 cells, and the mechanism may be related to the cytoprotective substance superoxide dismutase (SOD) is related to the level of glutathione (GSH). Overall, our findings indicate that compound CZM-3-5 has potential antioxidant activity in vitro.
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6

Westerberg, Arthur W. "Synthesis in engineering design". Computers & Chemical Engineering 13, n.º 4-5 (abril de 1989): 365–76. http://dx.doi.org/10.1016/0098-1354(89)85016-1.

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7

Juneja, Chetan y Hemant Kothari. "Business Agility: A Systematic Review of Literature and Design Oriented Research Synthesis". Journal of Advances and Scholarly Researches in Allied Education 15, n.º 6 (5 de julio de 2018): 198–218. http://dx.doi.org/10.29070/15/57760.

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8

Xuesong Wang and Xiaorong Tang, Xuesong Wang and Xiaorong Tang. "Design, Synthesis and Evaluate In Vitro Antifungal Activity of Novel Benzamide Derivatives". Journal of the chemical society of pakistan 41, n.º 3 (2019): 549. http://dx.doi.org/10.52568/000763/jcsp/41.03.2019.

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A series of novel benzamide derivatives according to fluopicolide were designed and synthesized following the rule of combination carboxylic acid amides and amines derivatives together. The antifungal activity of the 15 new compounds were evaluated in vitro against five pathogenic fungi, including Sclerotinia sclerotiorum, Gibberella zeae, Rhizoctonia solani, Helminthosporium maydis and Botrytis cinerea. Almost all the structure have not been reported, except compounds 3, 5 and 6. A surprising finding is that all the five tested fungi breed faster than negative controls when supplementary with compound 715 , respectively.
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9

Nascimento, A. R. do, R. L. B. de A. Medeiros, M. A. de F. Melo, D. M. de A. Melo y M. J. B. de Souza. "Optimization of MCM-48 synthesis using factorial design". Cerâmica 62, n.º 364 (diciembre de 2016): 413–17. http://dx.doi.org/10.1590/0366-69132016623642028.

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Abstract MCM-48 mesoporous materials were hydrothermally synthesized according to the 22 factorial design by varying the crystallization time and temperature of the synthesis gel, and characterized by means of X-ray diffraction analysis and adsorption of N2. In the crystallization temperature and time conditions used, specific areas between 924 to 1102 m2.g-1, pore volumes between 0.015 to 0.087 cm3.g-1 and pore diameters between 3.2 to 4.0 nm were obtained. It was observed that for the syntheses performed at high temperature, the crystallization time should be reduced so that the material structure is formed.
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10

KARAKULOV, Maksim. "GDS-19 GEOMETRICAL SYNTHESIS OF A PLUNGERS ENGAGEMENT(DESIGN AND SYNTHESIS OF A PAIR OF GEARS OR OF GEAR TRAINS)". Proceedings of the JSME international conference on motion and power transmissions 2009 (2009): 98–101. http://dx.doi.org/10.1299/jsmeimpt.2009.98.

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11

Helander, Martin G. "Using Design Equations for Design Analysis and Synthesis". Proceedings of the Human Factors and Ergonomics Society Annual Meeting 50, n.º 18 (octubre de 2006): 2158–62. http://dx.doi.org/10.1177/154193120605001809.

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12

Macchi, Marco. "Design synthesis – integrated product and manufacturing system design". Production Planning & Control 27, n.º 4 (15 de diciembre de 2015): 343. http://dx.doi.org/10.1080/09537287.2015.1085679.

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13

Xu, Q. L., S. K. Ong y A. Y. C. Nee. "Function-based design synthesis approach to design reuse". Research in Engineering Design 17, n.º 1 (21 de abril de 2006): 27–44. http://dx.doi.org/10.1007/s00163-006-0015-5.

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14

Xue Kun Liu, Xue Kun Liu, Yan Qiu Wang Yan Qiu Wang, Tong Jian Zhao Tong Jian Zhao, Yuan Hua Lu Yuan Hua Lu, Jia Nan Zhao Jia Nan Zhao, Xiao Yu Geng Xiao Yu Geng y Jie Ma Jie Ma. "Design and Synthesis of 7-Azaindole Derivatives and Their Antitumor and Analgesic Activities". Journal of the chemical society of pakistan 42, n.º 3 (2020): 460. http://dx.doi.org/10.52568/000641.

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To develop effective anti-tumor and analgesic drugs, a series of novel 7-azaindole derivatives were designed and synthesized through a four-step reaction. 18 target compounds were obtained and characterized through Nuclear Magnetic Resonance and High Resolution Mass Spectrometry. Their anti-proliferative activities and analgesic effect were evaluated. When the 1-position was a methylsulfonyl group and the 5-position was a nitro group, compound 4f demonstrated the best activity. Furthermore, there was a dramatic difference between the IC50 values of compound 4f in tumor and in healthy cell line. The IC50 values of compound 4f in MCF7 breast cancer cell line was 5.781 μmol/L and 8.077 μmol/L in HepG2 hepatoma carcinoma cell line, but more than 100 μmol/L in HL7702 liver cell line. Preliminary results showed that compounds 3a, 3g and 4i had significant analgesic effects in mice, which were stronger than aspirin. These compounds have good prospects for new drug development.
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15

Xue Kun Liu, Xue Kun Liu, Yan Qiu Wang Yan Qiu Wang, Tong Jian Zhao Tong Jian Zhao, Yuan Hua Lu Yuan Hua Lu, Jia Nan Zhao Jia Nan Zhao, Xiao Yu Geng Xiao Yu Geng y Jie Ma Jie Ma. "Design and Synthesis of 7-Azaindole Derivatives and Their Antitumor and Analgesic Activities". Journal of the chemical society of pakistan 42, n.º 3 (2020): 460. http://dx.doi.org/10.52568/000641/jcsp/42.03.2020.

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To develop effective anti-tumor and analgesic drugs, a series of novel 7-azaindole derivatives were designed and synthesized through a four-step reaction. 18 target compounds were obtained and characterized through Nuclear Magnetic Resonance and High Resolution Mass Spectrometry. Their anti-proliferative activities and analgesic effect were evaluated. When the 1-position was a methylsulfonyl group and the 5-position was a nitro group, compound 4f demonstrated the best activity. Furthermore, there was a dramatic difference between the IC50 values of compound 4f in tumor and in healthy cell line. The IC50 values of compound 4f in MCF7 breast cancer cell line was 5.781 μmol/L and 8.077 μmol/L in HepG2 hepatoma carcinoma cell line, but more than 100 μmol/L in HL7702 liver cell line. Preliminary results showed that compounds 3a, 3g and 4i had significant analgesic effects in mice, which were stronger than aspirin. These compounds have good prospects for new drug development.
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16

Stoineva, Ivanka B., Boris P. Galunsky, Valentin S. Lozanov, Ivailo P. Ivanov y Dimiter D. Petkov. "Enzymic synthesis design and enzymic synthesis of aspartame". Tetrahedron 48, n.º 6 (enero de 1992): 1115–22. http://dx.doi.org/10.1016/s0040-4020(01)88207-7.

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17

Xie, Yuan, Jiang Xu y Wayne Wolf. "Augmenting Platform-Based Design with Synthesis Tools". Journal of Circuits, Systems and Computers 12, n.º 02 (abril de 2003): 125–42. http://dx.doi.org/10.1142/s0218126603000702.

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Platform-based design faces an essential tension: it wants to reuse previous designs to leverage IP; but new designs must necessarily include work that is not complete or well-characterized. Synthesis and analysis methods are therefore important elements in platform-based design methodologies. This paper describes two aspects of this problem. First, we consider the first-generation dilemma, in which we must use additional analysis in order to create the first generation of a platform. Second, we describe a synthesis method that creates accelerators for platforms whose clock periods have been optimized for the system characteristics.
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18

Cagan, Jonathan, Matthew I. Campbell, Susan Finger y Tetsuo Tomiyama. "A Framework for Computational Design Synthesis: Model and Applications". Journal of Computing and Information Science in Engineering 5, n.º 3 (1 de septiembre de 2005): 171–81. http://dx.doi.org/10.1115/1.2013289.

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The field of computational design synthesis has been an active area of research for almost half a century. Research advances in this field have increased the sophistication and complexity of the designs that can be synthesized, and advances in the speed and power of computers have increased the efficiency with which those designs can be generated. Some of the results of this research have begun to be used in industrial practice, yet many open issues and research challenges remain. This paper provides a model of the automated synthesis process as a context to discuss research in the area. The varied works of the authors are discussed as representative of the breadth of methods and results that exist under the field of computational design synthesis. Furthermore, some guidelines are presented to help researchers and designers find approaches to solving their particular design problems using computational design synthesis.
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19

Thalken, Jason, Stephan Haas y A. F. J. Levi. "Synthesis for semiconductor device design". Journal of Applied Physics 98, n.º 4 (15 de agosto de 2005): 044508. http://dx.doi.org/10.1063/1.2014942.

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20

Anderson, Richard y Jon Kolko. "On logic, research, design synthesis…". Interactions 15, n.º 2 (marzo de 2008): 80. http://dx.doi.org/10.1145/1340961.1340983.

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21

Langrish, John. "DESIGN MANAGEMENT RESEARCH-Synthesis Squared". Design Management Journal (Former Series) 3, n.º 4 (10 de junio de 2010): 10–13. http://dx.doi.org/10.1111/j.1948-7169.1992.tb00598.x.

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22

Dutt, N. D. y D. D. Gajski. "Design synthesis and silicon compilation". IEEE Design & Test of Computers 7, n.º 6 (diciembre de 1990): 8–23. http://dx.doi.org/10.1109/54.64954.

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23

Goldin, Daniel S., Samuel L. Venneri y Ahmed K. Noor. "New frontiers in design synthesis". Acta Astronautica 44, n.º 7-12 (abril de 1999): 407–18. http://dx.doi.org/10.1016/s0094-5765(99)00087-9.

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24

Emptage, Michael R. "Experimental Design and Chemical Synthesis". Technometrics 39, n.º 2 (mayo de 1997): 231. http://dx.doi.org/10.1080/00401706.1997.10485095.

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25

Ishida, Manabu, Naoshi Dohmae, Yoshitsugu Shiro, Tadatake Oku, Tetsutaro Iizuka y Yasuhiro Isogai. "Design and Synthesis ofde NovoCytochromesc†". Biochemistry 43, n.º 30 (agosto de 2004): 9823–33. http://dx.doi.org/10.1021/bi049546e.

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26

Wender, Paul A., Ryan V. Quiroz y Matthew C. Stevens. "Function through Synthesis-Informed Design". Accounts of Chemical Research 48, n.º 3 (5 de marzo de 2015): 752–60. http://dx.doi.org/10.1021/acs.accounts.5b00004.

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27

Turnbull, W. Bruce y J. Fraser Stoddart. "Design and synthesis of glycodendrimers". Reviews in Molecular Biotechnology 90, n.º 3-4 (mayo de 2002): 231–55. http://dx.doi.org/10.1016/s1389-0352(01)00062-9.

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28

Hendrickson, James B. y Ping Huang. "Multiple constructions in synthesis design". Journal of Chemical Information and Modeling 29, n.º 3 (1 de agosto de 1989): 145–51. http://dx.doi.org/10.1021/ci00063a002.

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29

Guerra, Concettina y Rami Melhem. "Synthesis of systolic algorithm design". Parallel Computing 12, n.º 2 (noviembre de 1989): 195–207. http://dx.doi.org/10.1016/0167-8191(89)90053-7.

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30

Müllen, Klaus y Timothy M. Swager. "Advanced Polymer Design and Synthesis". Accounts of Chemical Research 41, n.º 9 (16 de septiembre de 2008): 1085. http://dx.doi.org/10.1021/ar800180w.

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31

Müller, Christian, Evgeny A. Pidko, Daniel Totev, Martin Lutz, Anthony L. Spek, Rutger A. van Santen y Dieter Vogt. "Atropisomeric phosphinines: design and synthesis". Dalton Transactions, n.º 46 (2007): 5372. http://dx.doi.org/10.1039/b715197g.

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32

Keddie, Daniel J., Graeme Moad, Ezio Rizzardo y San H. Thang. "RAFT Agent Design and Synthesis". Macromolecules 45, n.º 13 (21 de mayo de 2012): 5321–42. http://dx.doi.org/10.1021/ma300410v.

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33

Ampelli, Claudio. "Electrode design for ammonia synthesis". Nature Catalysis 3, n.º 5 (mayo de 2020): 420–21. http://dx.doi.org/10.1038/s41929-020-0461-x.

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34

de Geus, A. J. "Logic synthesis speeds ASIC design". IEEE Spectrum 26, n.º 8 (agosto de 1989): 27–31. http://dx.doi.org/10.1109/6.30776.

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35

Hensel, Michael y Achim Menges. "Material and digital design synthesis". Architectural Design 76, n.º 2 (2006): 88–95. http://dx.doi.org/10.1002/ad.244.

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36

Kotha, Sambasivarao, Nageswara Rao Panguluri y Rashid Ali. "Design and Synthesis of Spirocycles". European Journal of Organic Chemistry 2017, n.º 36 (24 de julio de 2017): 5316–42. http://dx.doi.org/10.1002/ejoc.201700439.

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37

Freudenstein, Ferdinand. "Mechanism design: Analysis and synthesis". Mechanism and Machine Theory 20, n.º 1 (enero de 1985): 81. http://dx.doi.org/10.1016/0094-114x(85)90061-8.

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38

Dhingra, Anoop K. "Mechanism design: Analysis and synthesis". Mechanism and Machine Theory 28, n.º 5 (septiembre de 1993): 727–28. http://dx.doi.org/10.1016/0094-114x(93)90015-n.

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39

Lu, Stephen C. Y. y Ang Liu. "Abductive reasoning for design synthesis". CIRP Annals 61, n.º 1 (2012): 143–46. http://dx.doi.org/10.1016/j.cirp.2012.03.062.

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40

Ungvarská Maľučká, Lucia y Jozef Csöllei. "Design, Synthesis and Biological Activity of New Carbamate Cholinesterase Inhibitors". Chemické listy 116, n.º 6 (10 de junio de 2022): 372–80. http://dx.doi.org/10.54779/chl20220372.

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The work deals with the design, synthesis and biological activity of new carbamate cholinesterase inhibitors. It is focused on selected syntheses of new carbamate derivatives, which were tested for their anticholinesterase activity against acetylcholinesterase as well as butyrylcholinesterase. Despite various theories in the pathogenesis of Alzheimer's disease, drugs that can inhibit these two enzymes still represent the major approach to the treatment of this neurodegenerative disease. Many of the newly synthesized compounds have unique chemical structure. Recently, the approach to the synthesis of new cholinesterase inhibitors has focused on the preparation of potential drugs, containing in their chemical structure fragments of already known drugs, commonly used in the pharmacotherapy of Alzheimer's disease, but also other diseases. The aim of preparing these compounds is to affect several biological systems simultaneously. These multipotent compounds have been termed "multi-target-directed ligands"; the molecules of drugs used to treat Alzheimer's disease always contain a pharmacophore acting as a cholinesterase inhibitor, which represents the mainstay of therapy.
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41

Vetica, Fabrizio, Fabiana Pandolfi, Luca Pettazzoni, Francesca Leonelli y Martina Bortolami. "Organocatalyst Design for the Stereoselective Annulation towards Bicyclic Diketones and Analogues". Symmetry 14, n.º 2 (10 de febrero de 2022): 355. http://dx.doi.org/10.3390/sym14020355.

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The Wieland–Miescher ketone, Hajos–Parrish–Eder–Sauer–Wiechert ketone, and their analogues are bicyclic diketones essential as building blocks for the synthesis of several natural and bioactive molecules. For this reason, since 1971, when Hajos and Parrish and Eder, Sauer, and Wiechert reported the stereoselective synthesis of these compounds promoted by L-proline, numerous methodologies and organocatalysts have been studied over the years with the aim of identifying increasingly efficient asymmetrical syntheses of these bicyclic ketones. This review will outline the methodological and stereochemical features of the organocatalytic stereoselective synthesis of these bicyclic scaffolds based on the different organocatalysts employed from 1971 until today. Particular emphasis will be given to the structural features of the catalysts and to the reaction conditions.
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42

Montastruc, Ludovic, Ségolène Belletante, Alexandre Pagot, Stéphane Negny y Ludovic Raynal. "From conceptual design to process design optimization: a review on flowsheet synthesis". Oil & Gas Science and Technology – Revue d’IFP Energies nouvelles 74 (2019): 80. http://dx.doi.org/10.2516/ogst/2019048.

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This paper presents the authors’ perspectives on some of the open questions and opportunities in Process Systems Engineering (PSE) focusing on process synthesis. A general overview of process synthesis is given, and the difference between Conceptual Design (CD) and Process Design (PD) is presented using an original ternary diagram. Then, a bibliometric analysis is performed to place major research team activities in the latter. An analysis of ongoing work is conducted and some perspectives are provided based on the analysis. This analysis includes symbolic knowledge representation concepts and inference techniques, i.e., ontology, that is believed to become useful in the future. Future research challenges that process synthesis will have to face, such as biomass transformation, shale production, response to spaceflight demand, modular plant design, and intermittent production of energy, are also discussed.
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43

Campbell, Matthew I., Jonathan Cagan y Kenneth Kotovsky. "The A-Design approach to managing automated design synthesis". Research in Engineering Design 14, n.º 1 (febrero de 2003): 12–24. http://dx.doi.org/10.1007/s00163-002-0025-x.

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44

Noji, Tamotsu, Keisuke Shimizu, Hideyuki Hamada y Akira Nakamura. "Design and implementation of synthesis prediction in RTL design". Systems and Computers in Japan 27, n.º 11 (1996): 41–52. http://dx.doi.org/10.1002/scj.4690271104.

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45

Edie Sasito, Edie Sasito, Bambang Soegijono y Azwar Manaf. "Structure and Design Flow Injection Synthesis Method of Co-precipitation Forming Magnetic Materials Process". Indian Journal of Applied Research 3, n.º 9 (1 de octubre de 2011): 403–7. http://dx.doi.org/10.15373/2249555x/sept2013/119.

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46

Golovan, І. V., O. M. Popovych y V. O. Polishchuk. "THE DESIGN SYNTHESIS TOOLS OF SUBMERSIBLE INDUCTION MOTORS OF INNOVATIVE СONSTRUCTURES". Praci Institutu elektrodinamiki Nacionalanoi akademii nauk Ukraini 2022, n.º 63 (21 de noviembre de 2022): 40–44. http://dx.doi.org/10.15407/publishing2022.63.040.

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The expediency of conducting research in the direction of improving the energy efficiency of submersible induction motors due to the introduction of a set of tools for the design synthesis of their innovative designs was reasoned. Means of design synthesis of submersible induction motors of innovative designs are considered. The combination of which in the implementation of the design will allow to increase the level of improvement of submersible induction motors in accordance with the requirements for modern equipment, such as: reliability, energy efficiency, economy. The results of realization of the induction motor optimal design synthesis of the submersible pump of an innovative design on the basis of the ПЭДВ 2.8-140 motor by criterion of a maximum efficiency are resulted. Ref. 10, fig. 2, table.
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47

Hendrickson, J. B. y A. G. Toczko. "Synthesis design logic and the SYNGEN (synthesis generation) program". Pure and Applied Chemistry 60, n.º 11 (1 de enero de 1988): 1563–72. http://dx.doi.org/10.1351/pac198860111563.

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48

Kapelevich, Alex. "GDS-17 DIRECT DESIGN OF ASYMMETRIC GEARS : APPROACH AND APPLICATION(DESIGN AND SYNTHESIS OF A PAIR OF GEARS OR OF GEAR TRAINS)". Proceedings of the JSME international conference on motion and power transmissions 2009 (2009): 87–91. http://dx.doi.org/10.1299/jsmeimpt.2009.87.

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49

Zhang, Ming Ming, Shu Guang Zhao y Xu Wang. "Reversible Logic Synthesis-Oriented Multi-Objective Automatic Design Method Based on Evolutionary Design Techniques". Key Engineering Materials 439-440 (junio de 2010): 534–39. http://dx.doi.org/10.4028/www.scientific.net/kem.439-440.534.

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This paper applies evolutionary design techniques to the reversible logic synthesis, and proposes a reversible logic synthesis-oriented multi-objective automatic design method based on evolutionary design techniques. Firstly, build a gate-level array model of reversible logic circuits (RLC) in order to model the synthesis problems as ones of constrained multi-objective optimizations. Then, encode the candidate RLC to a set of binary evolutionary individuals which are solved by the specialized Pareto-optimal multi-objective evolutionary algorithm. In addition, adopt “pre-bit priority” mechanism to repair infeasible individuals and adopt the rule-based local transformation method to simple the redundant RLC. The results of synthesis experiments demonstrate that the proposed method is feasible and effective, and can automatically synthesize the better RLC.
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50

Rana, L. y B. Chudoba. "Demonstration of a prototype design synthesis capability for space access vehicle design". Aeronautical Journal 124, n.º 1281 (30 de junio de 2020): 1761–88. http://dx.doi.org/10.1017/aer.2020.55.

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ABSTRACTThe early conceptual design (CD) phase of space access vehicles (SAVs) is the most abstract, innovative and technologically challenging phase of the entire aerospace design life cycle. Although the design decision-making during this phase influences around 80 percent of the overall life cycle cost, it is the most abstract and thus least understood phase of the entire design life cycle. The history of SAV design provides numerous examples of project failures that could have been avoided if the decision-maker had had the capability to forecast the potential risks and threats correctly ahead of time during the conceptual design phase. The present study addresses this crucial phase and demonstrates a best-practice synthesis methodology prototype to advance the current state of the art of CD as applied to SAV design. Developed by the Aerospace Vehicle Design (AVD) Laboratory at the University of Texas at Arlington (UTA), the Aerospace Vehicle Design Synthesis process and software (AVDS) is a prototype solution for a flight vehicle configuration–flexible (generic) design synthesis capability that can be applied to the primary categories of SAVs. This study focusses on introducing AVDS, followed by the demonstration and verification of the system’s capability through a sizing case study based on the data-rich Boeing X-20 Dyna-Soar spaceplane.
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