Literatura académica sobre el tema "Sugp1"
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Artículos de revistas sobre el tema "Sugp1"
Liu, Zhaoqi, Jian Zhang, Yiwei Sun, Tomin E. Perea-Chamblee, James L. Manley y Raul Rabadan. "Pan-cancer analysis identifies mutations in SUGP1 that recapitulate mutant SF3B1 splicing dysregulation". Proceedings of the National Academy of Sciences 117, n.º 19 (24 de abril de 2020): 10305–12. http://dx.doi.org/10.1073/pnas.1922622117.
Texto completoAlsafadi, Samar, Stephane Dayot, Malcy Tarin, Alexandre Houy, Dorine Bellanger, Michele Cornella, Michel Wassef et al. "Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancers". Oncogene 40, n.º 1 (14 de octubre de 2020): 85–96. http://dx.doi.org/10.1038/s41388-020-01507-5.
Texto completoBenbarche, Salima, Jose Maria Bello Pineda, Laura Baquero Galvis, Bo Liu, Jeetayu Biswas, Eric Wang, K. Ashley Lyttle et al. "Synthetic Introns Identify the Novel RNA Splicing Factor GPATCH8 As Required for Mis-Splicing Induced By SF3B1 Mutations". Blood 142, Supplement 1 (28 de noviembre de 2023): 3. http://dx.doi.org/10.1182/blood-2023-179848.
Texto completoZhang, Jian, Abdullah M. Ali, Yen K. Lieu, Zhaoqi Liu, Jianchao Gao, Raul Rabadan, Azra Raza, Siddhartha Mukherjee y James L. Manley. "Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1". Molecular Cell 76, n.º 1 (octubre de 2019): 82–95. http://dx.doi.org/10.1016/j.molcel.2019.07.017.
Texto completoFeng, Qing, Keegan Krick, Jennifer Chu y Christopher B. Burge. "Splicing quality control mediated by DHX15 and its G-patch activator SUGP1". Cell Reports 42, n.º 10 (octubre de 2023): 113223. http://dx.doi.org/10.1016/j.celrep.2023.113223.
Texto completoDeng, Guo-Xiong, Rui-Xing Yin, Yao-Zong Guan, Chun-Xiao Liu, Peng-Fei Zheng, Bi-Liu Wei, Jin-Zhen Wu y Liu Miao. "Association of the NCAN-TM6SF2-CILP2-PBX4-SUGP1-MAU2 SNPs and gene-gene and gene-environment interactions with serum lipid levels". Aging 12, n.º 12 (22 de junio de 2020): 11893–913. http://dx.doi.org/10.18632/aging.103361.
Texto completoLiu, Xinglin, Zengchun Wang, Yanping Jiang, Libo Huang, Xuejun Yuan, Yang Li, Ning Jiao, Weiren Yang y Shuzhen Jiang. "Quantitative Proteomic Analysis of Zearalenone Exposure on Uterine Development in Weaned Gilts". Toxins 14, n.º 10 (9 de octubre de 2022): 692. http://dx.doi.org/10.3390/toxins14100692.
Texto completoArslanow, A., C. S. Stokes, F. Grünhage, F. Lammert y M. Krawczyk. "P1048 : Effects of prosteatogenic TM6SF2 and NCAN/SUGP1 variants on hepatic steatosis and non-invasive markers of liver injury in patients with chronic liver diseases". Journal of Hepatology 62 (abril de 2015): S741—S742. http://dx.doi.org/10.1016/s0168-8278(15)31246-0.
Texto completoGhodsian, Nooshin, Erik Abner, Émilie Gobeil, Nele Taba, Alexis St Amand, Nicolas Perrot, Christian Couture et al. "Electronic Health Record-Based Genome-Wide Meta-Analysis Identifies New Susceptibility Loci for Non-Alcoholic Fatty Liver Disease". Journal of the Endocrine Society 5, Supplement_1 (1 de mayo de 2021): A501. http://dx.doi.org/10.1210/jendso/bvab048.1024.
Texto completoPatterton, D. y J. Hapgood. "suGF1 binds in the major groove of its oligo(dG).oligo(dC) recognition sequence and is excluded by a positioned nucleosome core". Molecular and Cellular Biology 14, n.º 2 (febrero de 1994): 1410–18. http://dx.doi.org/10.1128/mcb.14.2.1410-1418.1994.
Texto completoTesis sobre el tema "Sugp1"
Canbezdi, Christine. "Rôle des mutations de SF3B1 et SUGP1 dans l'épissage aberrant des cancers humains". Electronic Thesis or Diss., Université Paris sciences et lettres, 2024. http://www.theses.fr/2024UPSLS049.
Texto completoAmong the splicing genes involved in cancers, SF3B1 is the most frequently mutated in blood diseases and some solid tumors. Recurrent SF3B1 mutations result in recognition of an alternative 3' splice site, resulting in aberrant mRNAs with partial intron retention. Other SF3B1 mutations are found in cancers without their consequences being known. Furthermore, hypomorphic mutations in SUGP1, found especially in some lung adenocarcinomas, have been associated with an aberrant splicing signature similar to that observed for SF3B1 mutants. However, the functional role of SUGP1 in aberrant splicing in cancers is poorly characterized.We used the aberrant splicing signature of SF3B1 as a marker of the functional impact of SF3B1 mutations. Using 3D modeling, we then predicted the consequences of this functional impact on the protein conformation of SF3B1 mutants.Our results reveal that SF3B1 mutations do not cause the same pathogenicity in cancers depending on the position of the mutated codon and the amino acid substitution. This appears to correlate positively with the change in protein conformation at the N-terminal region of SF3B1.To better understand the function of SUGP1, we generated by CRISPR/Cas9 an isogenic cell model exhibiting partial inactivation of SUGP1. The functional consequences as well as the composition of the spliceosome in the presence of the SUGP1 mutant by mass spectrometry were studied.CRISPR/Cas9 model with partial SUGP1 inactivation reproduces splicing abnormalities in cancers. We showed that a strong positive selection pressure exists on SUGP1, leading to the appearance of spontaneous revertants. Our results show that one of the revertants without a ULM domain, but containing a G-patch domain, partially reproduces these splicing abnormalities. It appears to interfere with the composition of the spliceosome, especially U2 snRNP complex, and allows us to understand more about the function of SUGP1.Overall, this work showed that the functional consequences of SF3B1 mutations impact the protein conformation of SF3B1 mutants. It allowed us to refine the current spliceosome action model in relation to SUGP1 and to understand its dynamics in relation to other partners such as SF3B1, of great importance in physiology and cancer
Scherer, Sonja Daniela. "Protein purification and cDNA cloning of suGF1 : a sea urchin nuclear DNA-binding factor". Doctoral thesis, University of Cape Town, 1998. http://hdl.handle.net/11427/21905.
Texto completoUlker, Fatma Demet. "Active Vibration Control Of Smart Structures". Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/4/1098409/index.pdf.
Texto completocontrol strategies in order to suppress the free and forced vibrations of smart structures. The smart structures analyzed in this study were the smart beam and the smart ¯
n. They were aluminum passive structures with surface bonded PZT (Lead-Zirconate-Titanate) patches. The structures were considered in clamped-free con¯
guration. The ¯
rst part of this study focused on the identi¯
cation of nominal system models of the smart structures from the experimental data. For the experimentally identi¯
ed models the robust controllers were designed by using H1 and ¹
-synthesis strategies. In the second part, the controller implementation was carried out for the suppression of free and forced vibrations of the smart structures. Within the framework of this study, a Smart Structures Laboratory was established in the Aerospace Engineering Department of METU. The controller implementations were carried out by considering two di®
erent experimental set-ups. In the ¯
rst set-up the controller designs were based on the strain measurements. In the second approach, the displacement measurements, which were acquired through laser displacement sensor, were considered in the controller design. The ¯
rst two °
exural modes of the smart beam were successfully controlled by using H1 method. The vibrations of the ¯
rst two °
exural and ¯
rst torsional modes of the smart ¯
n were suppressed through the ¹
-synthesis. Satisfactory attenuation levels were achieved for both strain measurement and displacement measurement applications.
Koues, Olivia I. "The Epigenetic Regulation of Cytokine Inducible Mammalian Transcription by the 26S Proteasome". Digital Archive @ GSU, 2009. http://digitalarchive.gsu.edu/biology_diss/59.
Texto completoBhat, Kavita Purnanda. "Roles of the Ubiquitin-Proteasome System and Mono-ubiquitination in Regulating MHC class II Transcription". Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/biology_diss/82.
Texto completoKylarová, Salome. "Příprava a charakterizace vazebných partnerů fosducinu". Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-324646.
Texto completoMaganti, Nagini. "Role of 26S Proteasome and Regulator of G-Protein Signaling 10 in Regulating Neuroinflammation in the Central Nervous System". 2015. http://scholarworks.gsu.edu/biology_diss/162.
Texto completoLibros sobre el tema "Sugp1"
Southeast Asian Fisheries Development Center. Aquaculture Dept. Library & Documentation Services. y Brackishwater Aquaculture Information System, eds. Sugpo and other Philippine penaeids: A classified list of materials available at the SEAFDEC Aquaculture Department Library. Tigbauan, Iloilo, Philippines: Brackishwater Aquaculture Information System, SEAFDEC Aquaculture Dept., 1985.
Buscar texto completoSoutheast Asian Fisheries Development Center. Aquaculture Dept. Library. Sugpo and other Philippine penaeids: A classified list of materials available at the SEAFDEC Aquaculture Department Library. Tigbauan, Iloilo, Philippines: Brackishwater Aquaculture Information System, SEAFDEC Aquaculture Dept., 1987.
Buscar texto completoWeisweiller. The Foreign Exchange Man Supp1. Prentice Hall Europe (a Pearson Education company), 1991.
Buscar texto completoStaff, Houghton Mifflin Company. Houghton Mifflin Reading Leveled Readers: Tres Kit Lang Supp1. 1-1. 2. Houghton Mifflin Harcourt Publishing Company, 2003.
Buscar texto completoHoughton Mifflin Company. Houghton Mifflin Reading Leveled Readers: Tres Kit Lang Supp1. 1-1. 5. Houghton Mifflin Harcourt Publishing Company, 2003.
Buscar texto completoOECD Economic Outlook, Interim Report September 2011. OECD, 2011. http://dx.doi.org/10.1787/eco_outlook-v2011-sup1-en.
Texto completoPerspectives économiques de l'OCDE, Rapport intermédiaire septembre 2011. OECD, 2011. http://dx.doi.org/10.1787/eco_outlook-v2011-sup1-fr.
Texto completoOECD Economic Outlook, Interim Report September 2012. OECD, 2012. http://dx.doi.org/10.1787/eco_outlook-v2012-sup1-en.
Texto completoPerspectives économiques de l'OCDE, Rapport intermédiaire septembre 2012. OECD, 2012. http://dx.doi.org/10.1787/eco_outlook-v2012-sup1-fr.
Texto completoCapítulos de libros sobre el tema "Sugp1"
Goebel, Zane. "Superdiversity". En Handbook of Pragmatics, 221–38. Amsterdam: John Benjamins Publishing Company, 2018. http://dx.doi.org/10.1075/hop.21.sup1.
Texto completo"SUG1". En Encyclopedia of Genetics, Genomics, Proteomics and Informatics, 1896. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_16334.
Texto completoActas de conferencias sobre el tema "Sugp1"
Fabregas, Aleta C., Debrelie Cruz y Mark Daniel Marmeto. "SUGPO". En the 6th International Conference. New York, New York, USA: ACM Press, 2018. http://dx.doi.org/10.1145/3301551.3301574.
Texto completoMarquez, Guillermo, Lihong V. Wang, Mehrube Mehrubeoglu y Nasser Kehtarnavaz. "Imaging obliquely illuminated skin lesions for skin cancer detection". En Biomedical Optical Spectroscopy and Diagnostics. Washington, D.C.: OSA, 2000. http://dx.doi.org/10.1364/bosd.2000.sug1.
Texto completoYang, Shao, Darryl Keenan y Marla Dowell. "UV Pulse Response Nonlinearity of Two Si Photodiodes". En Asia Optical Fiber Communication and Optoelectronic Exposition and Conference. Washington, D.C.: OSA, 2008. http://dx.doi.org/10.1364/aoe.2008.sug1.
Texto completoMazzali, Claudio y Ming-Jun Li. "Recent Developments in Optical Fiber Technology and Their Impact Opening New Application Spaces". En Asia Optical Fiber Communication and Optoelectronic Exposition and Conference. Washington, D.C.: OSA, 2008. http://dx.doi.org/10.1364/aoe.2008.sup1.
Texto completoMizuno, Hitoshi, Akihiro Horii, Hiroki Hibino, Mamoru Kaneko, Kazuhiro Gono, Hirokazu Nishimura y Tetsuo Nonami. "New imaging technologies for endoscopic applications". En Biomedical Topical Meeting. Washington, D.C.: OSA, 2002. http://dx.doi.org/10.1364/bio.2002.sug1.
Texto completoPage, Álvaro, Nicolás Jara, José Luis Abad y José Navarro. "Validación de los marcadores ArUco para el análisis de movimientos humanos". En 11 Simposio CEA de Bioingeniería. València: Editorial Universitat Politècnica de València, 2019. http://dx.doi.org/10.4995/ceabioing.2019.10029.
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