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Chan, Chun-wai Raymond. "Bereavement of spouses of cancer patients". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B29726694.
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Hunt, Chantal K. "Stress, coping, and health in spouses of cancer patients". Columbus, Ohio : Ohio State University, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1080318948.
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Thesis (Ph. D.)--Ohio State University, 2004.Title from first page of PDF file. Document formatted into pages; contains x, 133 p.; also includes graphics. Includes abstract and vita. Advisor: Carol Kennedy, School of Nursing. Includes bibliographical references (p. 122-133).
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Rosenbaum, Deborah Ilse. "What's good for the gander is good for the goose helping cancer patients to cope by treating their spouses /". Diss., Online access via UMI:, 2006.
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Laverdière-Ranger, Lynn. "Breast cancer patients and their spouses, husbands' participation, worries and social support in the cancer experience". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape15/PQDD_0023/MQ31448.pdf.
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Winterling, Jeanette. "Hope and Despair : Philosophy of life, expectations and optimism in cancer patients and their spouses". Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7580.
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Dhanbhoora, Khushnud A. "Spousal communication among patients with cancer". Virtual Press, 2007. http://liblink.bsu.edu/uhtbin/catkey/1364940.
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Using primarily grounded theory methodology, the purpose of this study was to understand how the experience of cancer affects communication patterns in married couples where one spouse has been diagnosed with cancer. Nine couples, five in which women were diagnosed with cancer and four in which men were diagnosed with cancer, were interviewed individually. They were asked questions pertaining to changes in their relationship and communication patterns since the diagnosis of cancer. Potential barriers and facilitators to communication were explored. Additionally, gender differences that could play a role in these marital communication patterns were examined. Participants were also administered a measure of mood states, the Profile of Mood States (POMS) and, a measure of family cohesion, flexibility and communication, the Family Adaptability and Cohesion Evaluation Scale-version IV (FACES IV). Findings from both qualitative and quantitative methods were triangulated.Information gathered from the interviews generated eight themes: initial reactions to diagnosis, the experience of cancer, coping strategies, impact of cancer on the spousal relationship, spousal communication prior to cancer, spousal communication since the diagnosis of cancer, barriers to communication, and impact of gender and gender role on communication and adjustment. These categories and their subcategories generated an integrated grounded theory on the dimensions of communication. The theory consisted of three interactive elements: facilitators of communication, barriers to communication and the role of gender.Findings from this study confirmed existing trends in the current literature on communication among couples facing cancer. Results demonstrated that the experienceof cancer and its treatment brought couples closer to each other, where they experienced increased intimacy and communication with their spouses. There were several factors that facilitated these changes. On the other hand, barriers to communication were also identified; however, some of these barriers also served as coping strategies for participants. Furthermore, although there were differences and similarities noted among men and women in the study, results highlighted the importance of viewing them within the context of each participant's role as a patient and a caregiver, and not merely as a result of gender.Several research and practice implications are presented. Results of this study can help health care and mental health professionals gain a better understanding of the needs of cancer patients and their families. Couples and families can also benefit from an awareness of specific facilitators and barriers to communication.Department of Counseling Psychology and Guidance Services
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McFarlane, Michael J. "Volatile organic compound and microbiome profiling in patients with colorectal cancer, their spouses and first degree relatives". Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/111126/.
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Colorectal cancer (CRC) is the one of the commonest causes of cancer and cancer related death worldwide. Its aetiology is linked to a number of reversible and irreversible genetic and environmental factors, including age, sex, genetics, smoking and diet. There has been a drive in recent years for non-invasive biomarkers for many malignant and non-malignant diseases across multiple medical specialties. One of the areas of interest is the detection of volatile organic compounds (VOCs) in various bodily substances by means such as mass spectrometry and electronic noses. CRC patients have been shown to be distinguishable from healthy controls using urinary VOC detection in several studies, including two published by the research group at UHCW and the University of Warwick. There has also been much interest in recent years into the role that the intestinal microbiome plays in health and disease in humans. The aim of this thesis was to characterise the urinary VOC and stool microbiome profiles of CRC patients, their spouses and first degree relatives. The aim being to determine whether the urinary VOC profiles could be distinguished using this technology and to try and better understand the underlying mechanism which lead to CRC carcinogenesis. The first degree relatives and spouses were selected as “common gene pool” and “shared environment” control groups respectively. This work was done using an LC-FAIMS-MS hybrid machine to detect urinary VOCs and 16s RNA sequencing using an Illumina Miseq platform. Comparisons were also made between pre-treatment and post-treatment CRC samples to try and determine if there was any change in either VOC or microbiome profiles after CRC treatment. The urinary VOC profiles of CRC subjects could be distinguished from both sets of healthy controls using a 5-fold cross validation and sparse logistics regression and Random Forrest statistical classifiers, achieving sensitivities of 63-69%, specificities of 64-69% and AUC 0.71-0.72. No statistically significant differences could be found in the urinary VOC profiles of pre-operative and post operative samples. Microbiome analysis revealed over 1300 operational taxonomic units (OTUs), with a similarity of >93% between the CRC samples and the control groups, with significantly different bacterial abundances identified in only 82 OTUs (6.2%), mainly Clostridiales bacteria. Pre-treatment and post-treatment sample analysis revealed differences of 17 (3%) and 22 (4%) OTUs at 3 and 6 months respectively, again principally clostridiales. This thesis provides further data on the microbiome composition in CRC. It also provides further proof of the utility of urinary VOCs, for the first time here using LC-FAIMS-MS technology, a variant of the previously utilised FAIMS technology, as a non-invasive biomarker for CRC.
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Lewis, Adam Michael. "A terror management theory based intervention for anxiety in spouses of cancer patients: a multiple-baseline study". Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/2235.
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As the U.S. population ages the number of family caregivers is expected to rise. Family caregivers are a valuable source of informal healthcare services for patients and the public, in terms of reducing healthcare costs. However, research suggests family caregiving is not only financially costly for individuals, but associated with a number of medical and mental health risks, with spouses at higher risk for negative outcomes compared to other family members. Traditional evidence-based therapies for stress in family caregivers have been shown to be minimally efficacious with spouses. No therapies take into account the existential nature of spouse caregiver stress, including the potential nonconscious role of loss of life meaning/purpose and death anxiety. This study of multiple baseline design preliminarily explored the effects of a novel 8-week Terror Management Theory integrated existential psychotherapy (TIE) on stress and nonconscious mechanisms believed to function as buffers for existential anxiety, in five women with spouses receiving cancer treatment. Methods included ecological momentary assessment (EMA) of anxiety and self-esteem states via text message sent three times daily – and intermittent assessment of death anxiety, self-compassion, meaning in life, and quality of life at baseline, intervention, immediate post, and 1-month follow-up. Visual and statistical analyses indicated significant between-phase trend changes in anxiety and self-esteem within participants, although direction of changes varied across participants. Additionally, changes in death anxiety, self-compassion, meaning in life, and quality of life between phases varied across participants in directions inconsistent with intervention aims and participants’ subjective impressions of intervention-related changes. Mixed findings point to the complexity of spouse caregiver psychology and highlight the need for more effective therapies with this population. Results may also guide future research and development of existentially-informed therapies.
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Jenick, Marcus y n/a. "Couples Coping With End-Stage Cancer: The Influence of Attachment, Emotional Support, and Positive Meaning on Psychological Adjustment and Each Other". Griffith University. School of Applied Psychology, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030804.121524.
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This thesis was concerned with the psychological adjustment of 67 end-stage cancer patients, and three psychosocial variables considered to influence that adjustment: emotional support from spouse, positive meaning, and working models of attachment. Furthermore, this thesis was also concerned with the psychological adjustment of the patients' spouses, and the influence of emotional support from patient and working models of attachment on their adjustment. It was hypothesised that each of these psychosocial variables would directly influence the psychological adjustment of patients and spouses, measured using the negative affectivity scale of the Positive and Negative Affect Scale (PANAS). Furthermore, it was hypothesised that emotional support would influence positive meaning, and working models of attachment would influence both emotional support and positive meaning. Variables were measured via paper and pencil self-report inventories, with the exception of positive meaning, where verbal responses to an open question were coded. Univariate analyses indicated an association between patients' and spouses' emotional support provided by one another and their psychological adjustment. Univariate results also showed that patients' positive meaning was related to patients' psychological adjustment, and that patients' working models of attachment involving higher levels of attachment anxiety were associated with patients' poorer psychological adjustment. All these individual associations remained statistically significant after three control variables related to the patients' physical condition were taken into account. In addition, univariate analyses indicated that attachment was associated with emotional support, and that emotional support was associated with positive meaning. Following univariate analyses, variables were integrated into one model for patients and another for spouses using path analyses. Results were generally consistent with the prior sets of analyses. However, patients' working models of attachment involving higher levels of attachment anxiety no longer had a direct effect on patients' psychological adjustment to statistically significant levels. Rather, the influence of the working models of attachment on patients' psychological adjustment was mediated by emotional support. In addition, patients' positive meaning no longer had a significant direct effect on patients' psychological adjustment. The insignificant path coefficients between attachment anxiety and psychological adjustment, and between positive meaning and psychological adjustment, were attributed to the large amount of variance in negative affect due to emotional support. In summary, this research indicates that emotional support given and received between patients and spouses is important to the psychological adjustment of each party. Furthermore, emotional support influences patients' ability to construe positive meaning in their illness, although positive meaning does not appear to be as critical to the psychological adjustment of patients as emotional support. Working models of attachment influence the psychological adjustment of patients primarily through their influence on emotional support.
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Jenick, Marcus. "Couples Coping With End-Stage Cancer: The Influence of Attachment, Emotional Support, and Positive Meaning on Psychological Adjustment and Each Other". Thesis, Griffith University, 2003. http://hdl.handle.net/10072/365492.
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This thesis was concerned with the psychological adjustment of 67 end-stage cancer patients, and three psychosocial variables considered to influence that adjustment: emotional support from spouse, positive meaning, and working models of attachment. Furthermore, this thesis was also concerned with the psychological adjustment of the patients' spouses, and the influence of emotional support from patient and working models of attachment on their adjustment. It was hypothesised that each of these psychosocial variables would directly influence the psychological adjustment of patients and spouses, measured using the negative affectivity scale of the Positive and Negative Affect Scale (PANAS). Furthermore, it was hypothesised that emotional support would influence positive meaning, and working models of attachment would influence both emotional support and positive meaning. Variables were measured via paper and pencil self-report inventories, with the exception of positive meaning, where verbal responses to an open question were coded. Univariate analyses indicated an association between patients' and spouses' emotional support provided by one another and their psychological adjustment. Univariate results also showed that patients' positive meaning was related to patients' psychological adjustment, and that patients' working models of attachment involving higher levels of attachment anxiety were associated with patients' poorer psychological adjustment. All these individual associations remained statistically significant after three control variables related to the patients' physical condition were taken into account. In addition, univariate analyses indicated that attachment was associated with emotional support, and that emotional support was associated with positive meaning. Following univariate analyses, variables were integrated into one model for patients and another for spouses using path analyses. Results were generally consistent with the prior sets of analyses. However, patients' working models of attachment involving higher levels of attachment anxiety no longer had a direct effect on patients' psychological adjustment to statistically significant levels. Rather, the influence of the working models of attachment on patients' psychological adjustment was mediated by emotional support. In addition, patients' positive meaning no longer had a significant direct effect on patients' psychological adjustment. The insignificant path coefficients between attachment anxiety and psychological adjustment, and between positive meaning and psychological adjustment, were attributed to the large amount of variance in negative affect due to emotional support. In summary, this research indicates that emotional support given and received between patients and spouses is important to the psychological adjustment of each party. Furthermore, emotional support influences patients' ability to construe positive meaning in their illness, although positive meaning does not appear to be as critical to the psychological adjustment of patients as emotional support. Working models of attachment influence the psychological adjustment of patients primarily through their influence on emotional support.Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Applied Psychology
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Morgan, Mary Ann. "Cancer Patients with Pain: Examination of the Role of the Spouse/Partner Relationship In Mediating Quality of Life Outcomes for the Couple". [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002650.
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Miroglotta, Marissa L. "A Cross-Sectional Comparison of Psychosocial Adjustment among Spousal Caregivers for Hematopoietic Stem Cell Transplant Patients". Xavier University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=xavier1556140118018044.
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Blake, Holly. "Caregiver strain in spouses of stroke patients". Thesis, University of Nottingham, 2001. http://eprints.nottingham.ac.uk/10394/.
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The aim of this thesis was to identify both patient and carer factors relating to caregiver strain in spouses of stroke patients. The secondary aim was also to assess the effectiveness of an intervention in reducing levels of strain, involving the provision of cognitive assessment information to both patients and spouses. Previous research has not investigated specific cognitive impairment after stroke in relation to strain and reports of the relationship between patient disability and strain are not consistent. Assessment of physical function and detailed neuropsychological examination was carried out with stroke patients in Nottingham, Derby and Mansfield as part of a prospective, multicentre, single-blind randomised controlled trial. The assessment battery included measures of general mental state, language, perception, memory, executive function and praxis. Individualised information about cognitive function was provided in verbal and written form to each patient and carer. Carer strain was assessed in 57 spouses three and six months later. Around a third of spouses experienced significant strain. Results confirmed the importance of patient physical function with disability becoming an important factor with time. Basic self-care skills (Barthel Index) measured at three and six months, were significantly associated with carer strain at six months. Impairment of the patient's general mental state on the Mini-Mental State Examination (MMSE) and communication difficulties on the Sheffield Screening Test for Aphasia (SST) were related to carer strain and were also associated with emotional rather than physical strains. Carer strain was not significantly associated with other cognitive deficits, including impairments of perception, memory, executive function and praxis. Previous research has not assessed specific carer characteristics in relation to strain. In order to identify these, 222 spouses of stroke patients were sent questionnaire measures of strain, stress, mood, handicap, adjustment, social support, life satisfaction and personality and their perceptions of the patient's mood and independence in activities of daily living. Univariate analysis suggested that strain was associated with increased carer handicap, high stress, poor mood, 'chance' health locus of control, expression of depressed mood, low optimism, low positive affectivity, high negative affectivity and low self-esteem. Strain was also related to poor adjustment, low satisfaction with life, less emotional and practical support and a greater discrepancy between actual and ideal levels of support and increased help from professional services. Strained carers also perceived poor mood and increased disability in the stroke patient. Multivariate analysis indicated that the most important factors were low carer mood on the General Health Questionnaire-12 (GHQ-12), poor perceived patient independence in activities of daily living on the Extended Activities of Daily Living Scale (EADL) and high negative affectivity on the Positive and Negative Affect Schedule (PANAS). The relationship between these factors and strain needed to be tested prospectively. In a multicentre study of 116 spouses in Nottingham and Leicester, carers were sent the CSI, GHQ-12, EADL and PANAS at three and six months after the stroke. Again, over a third of carers experienced significant strain. Results confirmed those of the previous study and mood, perceived disability and negative affectivity at three months were found to predict high levels of carer strain six months after stroke. The most important caregiver factors were therefore the spouse's appraisal of their partner's disability, together with two emotional components of subjective well-being, one transient and one stable. The results also highlighted the role of other factors, including incontinence, disturbed sleep, communication difficulties and the amount of time spent caregiving in carer strain. Early identification of carers who may be at risk of strain later on will enable services to be targeted at prevention rather than cure. There was a non-significant trend towards reduced strain in carers who had received information about cognitive deficits after stroke. Spouses may benefit from individualised information about their partner's stroke. Strain is emotionally laden and services might focus on teaching effective coping strategies to reduce depression and provide emotional support. More research is needed to identify services that are effective in alleviating or indeed preventing strain. NB. This ethesis has been created by scanning the typescript original and may contain inaccuracies. In case of difficulty, please refer to the original text.
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Franzén-Dahlin, Åsa. "Psychological health and life situation in spouses of stroke patients /". Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-196-8/.
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Kärner, Anita. "Patients' and spouses' perspectives on coronary heart disease and its treatment /". Linköping : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-5264.
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Kärner, Anita. "Patients’ and Spouses’ Perspectives on Coronary Heart Disease and its Treatment". Doctoral thesis, Linköpings universitet, Hälsa, Aktivitet, Vård (HAV), 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-5264.
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Background: Lifestyle changes and drug treatment can improve the prognosis and quality of life for patients with coronary heart disease (CHD), but their co-operation with suggested treatment is often limited. The aim of this thesis was to study how patients and their spouses conceive CHD and its treatment. Material and Methods: The research design used was inductive and descriptive. The studies were based on three complementary sets of data. Patients with CHD (n=23) and spouses (n=25) were interviewed one year after an episode of the disease. Consecutive patients with CHD derived from another investigation were interviewed within six weeks or one year after the coronary event (n=113). All semi-structured interviews, tape-recorded or from notes taken by hand, were subjected to analysis within the phenomenographic framework. Findings: The patients’ conceptions of CHD varied and were vague, even as judged on a lay level. They were associated with symptoms rather than with the disease. Co-operation with drug treatment was rarely linked to improved prognosis. The patients’ descriptions of benefits from lifestyle changes and treatment did not give the impression of being based on a solid understanding of the importance of such changes. Incentives for lifestyle changes were classified into four categories, all of which contained both facilitating and constraining incentives. Somatic incentives featured direct and indirect physical signals. Social/practical incentives involved shared concerns, changed conditions, and factors connected with external environment. Cognitive incentives were characterised by active decisions and appropriated knowledge, but also by passive compliance with limited insights, and by the creating of routines. Affective incentives comprised fear and reluctance related to lifestyle changes and disease and also lessened self-esteem. All incentives mostly functioned facilitatively. The cognitive and the social/practical incentives were the most prevalent. Spouses’ understanding about the causes of CHD involved both appropriate conceptions and misconceptions. Drug treatment was considered necessary for the heart, but harmful to other organs. Spouses’ support to partners was categorised, and found to be contextually bound. The participative role was co-operative and empathetic. The regulative role controlled and demanded certain behaviours. The observational role was passive, compliant, and empathetic. The incapacitated role was empathetic, unable to support, and positive to changes. The dissociative role was negative to changes and reluctant to be involved in lifestyle changes. Conclusions: These results could be useful in the planning of care and education for CHD patients. The findings also emphasise the importance of adopting a family perspective to meet the complex needs of these patients and their spouses in order to facilitate appropriate lifestyle changes.On the day of the public defence of the doctoral thesis the status of article V was Submitted.
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Gunn, William Bessent. "Psychosocial factors affecting adaptation of patients and spouses to myocardial infarction". Diss., Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/49785.
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Chen, Hsien-Tzu. "Relational and transactional processes of couples' experience with breast cancer /". Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/7249.
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Davis, Nancy Lynn. "Perceptions of spouses of head injured survivors". Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/277111.
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This exploratory study was designed to discover the culture of living with a head injured spouse. Using the ethnographic approach, five spouses of head injured survivors were interviewed. Analysis of data yielded five domains of meaning: concerns as a result of role transition, social isolation, loss, future and coping. Two cultural themes emerged as "no one understands" and a "wish list." Implications for nursing practice include increasing awareness of health care professionals regarding perceptions and needs of spouses of head injured survivors.
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Engler, Jennifer [Verfasser]. "Cancer Care and Cancer Patients’ Experiences with Cancer / Jennifer Engler". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2019. http://d-nb.info/1180994191/34.
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Schreck, Janet Simon. "Marital Satisfaction in Spouses of Patients with Chronic Aphasia| A Mixed Methods Study". Thesis, University of Maryland, Baltimore, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3608641.
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Despite the prevalence of aphasia in the United States, there remains a dearth of research focusing specifically on the impact of chronic aphasia on marriage and marital satisfaction. This study used a sequential explanatory mixed methods design to explore marital satisfaction in spouses of patients with chronic aphasia. Results from the quantitative phase, involving 21 couples in which one spouse had aphasia resulting from stroke for more than one year, demonstrated a significant decrease in marital satisfaction in the non-aphasic spouse when comparing post-aphasia and retrospective recall of pre-aphasia marital satisfaction as measured using the Dyadic Adjustment Scale (p<.001). More severe aphasia was found to have a statistically significant correlation with lower post-aphasia marital satisfaction (r=.433, p=.05). Lower physical function scores in the non-aphasic spouse were also significantly correlated with lower post-aphasia marital satisfaction (r=.474, p=.03). The aim of a subsequent qualitative analysis of data obtained from 11 non-aphasia spouses from the original quantitative sample was to explain these findings. Two major concepts emerged from the qualitative data: living with loss and creating a new normal. Placed within the context of the ABCX crisis theory, incorporation of the quantitative and qualitative findings suggests that aphasia onset places a stress on the marriage. That stress is defined, in part, as a loss by the non-aphasic spouse. Findings suggest that many aspects of that loss are magnified in situations where the aphasia is more severe as the deficit in communication impacts intrapersonal and interpersonal elements of the marriage. The subcategories derived from the concept of creating a new normal describe the process of adaptation by non-aphasic spouse. The non-aphasic spouses' abilities to adapt, and their subsequent marital satisfaction, appeared related to their various definitions of the situation and availability of resources. Recognizing the complex relationship between chronic aphasia and marital satisfaction in the non-aphasic spouse may help speech-language pathologists and other health care providers provide more effective intervention strategies and better support for patients with aphasia and their spouses.
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Sidell, Nancy L. "The experience of community dwelling spouses of nursing home users : marital satisfaction, coping, and mental health /". The Ohio State University, 1998. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487949508369401.
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OLSSON, MILLA y CAROLINE ROSELL. "Telemedicine for Lung Cancer Patients". Thesis, KTH, Skolan för datavetenskap och kommunikation (CSC), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-136951.
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Den svenska sjukvården står idag för ett antal utmaningar om den skall fortsatt kunna erbjuda god service som vårdgivare och vara attraktiv som arbetsgivare. Bland annat diskuteras frågor som förvärrad platsbrist, läkarbrist samt avstånd till specialistsjukvård. På Karolinska Universitetssjukhuset i Solna ligger Radiumhemmet och där behandlas bland annat lungcancerpatienter. Där diskuteras huruvida telemedicin kan vara en möjlig väg för att lösa ovanstående problem. Denna uppsats utreder på vilket sätt telemedicin kan användas på Radiumhemmet för lungcancerpatienter. För att kunna utreda en telemedicinsk lösnings möjligheter på Radiumhemmet genomfördes intervjuer och fokusgrupper med personalen. Externa experter från sjukvården och industri intervjuades och ett besök gjordes på barnsjukhuset Childrens Healthcare of Atlanta, USA, där man har kommit långt i användningen av telemedicin. Det finns delar av verksamheten på Radiumhemmet där telemedicin skulle kunna bidra till att skapa möjligheter till en tätare kontakt mellan patient och vårdpersonal. Detta i syfte att lugna oroliga patienter och hjälpa till med lättare symptombedömningar och på så sätt minska väntetiderna. Genom de undersökningar som utfördes upptäcktes dock även svagheter i en telemedicinsk lösning avsedd för lungcancerpatienter. Patientgruppen ofta är äldre med liten erfarenhet av datorer och sjukdomen är allvarlig. Det krävs personlig kontakt och fysiska undersökningar, men i vilken utsträckning är individuellt. Telemedicin kanske inte kan ses som en absolut lösning för de problem som råder i sjukvården idag när det kommer till lungcancerpatienter, men väl som ett komplement. Om lungcancerpatienter är den optimala målgruppen är ifrågasättbart men att telemedicin kan underlätta i den svenska sjukvården står klart.Nowadays the health care system in Sweden is faced with several challenges like shortage of space, physicians and long distances to specialized health care. A possible solution for this being discussed at the lung cancer department of Karolinska University 2 Hospital is the use of telemedicine. If implemented it would be part of the followup treatment. The objective of our research is to find out if this technology can help improve the health care. In order to investigate the opportunity for a telemedicine solution, we collected qualitative data from multiple different sources. This included two doctors specialized in lung cancer, and a focus group with nurses from Radiumhemmet. We also conducted interviews with relevant individuals outside the hospital including Nirav Desai who is the Founder and CEO of Hands On Telehealth; furthermore, we visited the Children’s Healthcare of Atlanta based in Atlanta, Georgia where telemedicine is used on a daily basis. Thanks to the carried out research, we have discovered that telemedicine could be used in certain scenarios and contribute towards a more frequent contact between the patient and the medical professionals. Thus, this new technique could help nurses execute lighter symptoms assessment remotely and reduce waiting times. We also discovered some inconveniences in a telemedicine solution designed for lung cancer patients. We personally do not think they are the best target group for such a solution since the patients are mostly the elderly with little computer experience. Also the disease is severe and requires physical examinations where the telemedicine existing today would not improve the care giving. To all intents and purposes, telemedicine might not be the only and ultimate solution for the problems identified within healthcare for lung cancer patients at Radiumhemmet, but it can work well as a supplement. 3
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Fredrix, Elisabeth Wilhelmina Hubertina Maria. "Energy metabolism in cancer patients". Maastricht : Maastricht : Datawyse ; University Library, Maastricht University [Host], 1990. http://arno.unimaas.nl/show.cgi?fid=5567.
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Kaur, Jasmine. "Preventative Vaccine for Cancer patients". Thesis, Griffith University, 2022. http://hdl.handle.net/10072/413312.
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Cancer is an age-old disease and a leading cause of mortality worldwide. It starts with the development of abnormal cells that multiply to form tumours and may lead to metastasis causing damage to healthy tissues and organs of the body. Lung cancer is the most common type of cancer with significant morbidity and mortality globally and is of major concern for the society. Decades of research and innovation in the treatment of cancer led to the development of certain conventional therapies such as surgery, radiotherapy, and chemotherapy that are being effectively used. However, these traditional therapies have a disadvantage of destroying healthy cells and tissues in its close proximity, leading to other severe diseases and side effects. Therefore, a much-advanced approach to treat cancer without causing severe side effects became an important area of research. Improvements in the field of anti-cancer therapies led to a strategy to combine traditional treatment approaches to destroy cancer cells. Additionally, treatments such as targeted therapies, hormone therapy, and precision medicine came into existence. Alternatively, the immune system was analysed to determine an effective approach that could control proliferation of cancer cells and cause limited or no damage to other cells. This area of cancer therapeutics, known as immunotherapy, targets the immune system to enhance its ability of recognizing invasive neoplasms. Our immune system in response to an infection immediately activates immune cells, creating a protective immunity for decades. Unfortunately, this immune response often fails when fighting against cancer and is unable to entirely eliminate tumour cells or develop effective immunity. Cancer vaccines, a branch of immunotherapy that has potential therapeutic benefits can build immunity and ultimately lead to prevention from future illness. These have been employed to treat the disease using tumour associated antigens and various adjuvants or immune stimulators and only a few have been in clinical trials. The potential of such cancer vaccines can be exploited to further develop treatment strategies to prevent tumour occurrence and provide long-lasting immunity. This study was designed to primarily explore the potential of a novel immune stimulator, RNA:DNA hybrid and an established TLR9 agonist, CpG 7909. Furthermore, these agonists were used to develop a preventative cancer vaccine in association with a tumour associated carbohydrate antigen, Globo-H to determine whether the novel formulation could improve immune response and trigger antigen presentation in vitro and in vivo. In an in vivo setting, these were also investigated against lung cancer to determine their potential in preventing tumour occurrence. Within this study RAW 264.7 mouse macrophages were initially exposed to varying concentrations of CpG 7909, RNA:DNA hybrid, and Globo-H to determine the optimum dose concentration for the activation of antigen presenting cells by measuring the level of TNF-α secreted in cell culture supernatant. Following dose optimization, the individual agents were combined in a vaccine formulation, sharing the same antigen, where two cell lines, mouse RAW 264.7 macrophages and human monocytic cell line, THP-1 that was differentiated into macrophages and dendritic cells were exposed to the vaccines. TNF-α, IL-12 and IL-6 cytokine response was analysed as measured by ELISA and real-time PCR that were determined to be partially significant in response to the vaccines. The degree of immune response demonstrated by RNA:DNA hybrid-based vaccine (HG-Vax) confirmed that HG-Vax is more effective than CpG 7909-based vaccine (CG-Vax). This response was further analysed in an in vivo model where C57/BL mice were exposed to immune stimulators and vaccines separately for 14- and 28-days before end point termination. Serum was analysed for IL-12 and TNF-α to determine the level of inflammatory response. Even though statistical significance was not achieved in vivo, contrasting observations compared to the in vitro model were exhibited. Secretion of IL-12 in animals confirmed the induction of an anti-tumour immune response. Interestingly, cytokines induced by single dose CG-Vax persisted for a longer period of time in blood in comparison to HG-Vax. However, opposite was true with the booster immunization. In animal model of lung cancer, statistical significance validates that booster immunization with HG-Vax triggers an immune response and upregulates MHC II expression. Unfortunately, CG-Vax did not induce a significant immune response and failed to induce MHC II expression in an in vivo model of lung cancer. Although these findings present RNA:DNA hybrid to be a novel immune stimulator that may have the potential to be used in future cancer vaccinations, further investigation on its immunological potential and mechanism of action remains of need.Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Pharmacy & Med Sci
Griffith Health
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Choy, Yin-san Catherine y 蔡妍珊. "An exploratory study on anticipatory grieving: case studies of spouses of terminally ill patients". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1987. http://hub.hku.hk/bib/B31247799.
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Kalavina, Reuben. "Exploring the challenges and experiences of stroke patients and their spouses in Blantyre, Malawi". University of the Western Cape, 2014. http://hdl.handle.net/11394/4191.
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Magister Scientiae (Physiotherapy) - MSc(Physio)Stroke is the second leading cause of disability worldwide. Up to 60% of the survivors remain severely disabled. These people experience various challenges in such areas as self-care, mobility, accessing medical and rehabilitation services, transportation and finance. These affect them psychologically, physically and socially predisposing them to complications. Hospital based stroke records report on critical cases, which are not a true reflection of after effects of stroke in a community setting. The impact of stroke on patients and spouses cannot be underestimated considering that it is often sudden, giving no chance to patients or spouse to adjust to the predicament. The aim of this study was, therefore, to explore the challenges stroke patients and their spouses experienced during the rehabilitation process, from diagnosis through to treatment and discharge. The study was based on a qualitative approach, utilising an exploratory design. Data was collected using semi-structured in-depth interviews and focus group discussions. All interviews were tape recorded and transcribed verbatim. A thematic content analysis was used to analyse data. Ethical approval was sought from the University of the Western Cape and the College of Medicine Research Ethics Committee, University of Malawi. Permission was obtained from the General Manager of Malawi Against Physical Disabilities. The results indicates a range of challenges including dependence on spouse for basic self-care activities and activities of daily living, stress due to fear of dependence on their spouses, loss of opportunity for regular interaction with friends and family, limited facilities and accessibility to rehabilitation. Spouses are also burdened by of caregiving responsibilities. In conclusion, this study highlights that the consequences of stroke affect both patients and spouses in the areas of health, finance and social. There is need for rehabilitation professionals to give equal attention to the challenges experienced by spouses when managing stroke patients. The study recommends that accessibility to rehabilitation should be improved by increasing patients’ space at the centre, construction of more centres and expand CBR services to cover all districts in the country.
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Choy, Yin-san Catherine. "An exploratory study on anticipatory grieving : case studies of spouses of terminally ill patients /". [Hong Kong : University of Hong Kong], 1987. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12341575.
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St-Hilaire, Sylvie. "Quality of life : spouses of persons who have had a laryngectomy to treat cancer". Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23941.
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A qualitative study design was used to describe the quality of life as perceived by spouses of persons who have had a laryngectomy within the preceding two years to treat cancer. A convenience sample of 17 spouses of individuals with laryngectomies participated in this study.Data were collected through guided interviews. Data were analyzed according to Giorgi's (1985) phenomenological method of analysis. Spouses described their quality of life by referring to marital relationship, communication and life style. Spouses identified nine factors that affect their quality of life. These are stress, coping, social support, caring, knowledge, body image, uncertainty, emotional status, and physical function.
Findings from this study give the nurses an empirically derived perspective on the quality of life of spouses of individuals who have had a laryngectomy to treat cancer.
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Costar, Holly M. "Factors contributing to the development of posttraumatic Growth in Spouses of Breast Cancer Survivors". College Park, Md. : University of Maryland, 2005. http://hdl.handle.net/1903/2525.
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Thesis (M.A.) -- University of Maryland, College Park, 2005.Thesis research directed by: Dept. of Counseling and Personnel Services. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Bear, Francine. "Exploring the social construction of grief and loss in spouses following bereavement by cancer". Thesis, University of East London, 2016. http://roar.uel.ac.uk/5386/.
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Cancer bereavement may be associated with unique challenges involved in the caregiving experience, particularly for spouses, who commonly adopt this role. However, the dominance of quantitative and diagnostically informed research has produced a-contextual theories, which reinforce increasingly medicalised conceptualisations of grief. In contrast, less attention has been given to the subjective experience in this context, particularly from a discursive perspective. Three focus groups comprising an overall total of six men and 17 women were used to facilitate discussions between spouses who were bereaved by cancer. A Foucauldian-informed discourse analysis was employed to examine how participants constructed grief and loss, and to identify the broader discourses that served to shape these. Additional attention was paid to the rhetorical aspects of these constructions. Three overarching discursive ‘sites’ were identified: i) medicalisation; ii) individualism and iii) productivity and purpose. Analysis of the discursive activity illuminated how these discourses co-existed, creating tensions within constructions that highlighted an increasing professionalisation of grief, and also carried expectations for individuals to manage their grieving in private, via practices of self-regulation. These discourses offered subjugated positions and served to reinforce the power differentials that exist between the bereaved and professionals. However, those constructions that resisted positions of powerlessness and being silenced enabled individuals a greater sense of authority within bereavement and led them to feel more open and connected as a result. The findings draw attention to the expectation for bereaved individuals to protect society from their emotions. This has important implications for how grief may be better supported within clinical psychology settings and points to the need to challenge unhelpful assumptions within society.
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McMenamin, Úna. "Pharmacological exposures, cancer treatments and disease progression among cancer patients". Thesis, Queen's University Belfast, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.679267.
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The evidence base for the effect of common pharmacological exposures among patients diagnosed with cancer is sparse. Routinely collected health data however, can facilitate the conduct of pharmacoepidemiological research into cancer care and outcomes. This PhD study comprised (i) a systematic review of angiotensin-converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) use and cancer progression and survival; (ii) a systematic review and meta-analysis of non-steroidal anti-inflammatory drug (NSAID) use and colorectal cancer outcomes; (iii) a nested-case control study of ACEI and ARB use and risk of breast cancer mortality; (iv) a nested-case control study of ACEI and ARB use and risk of prostate cancer mortality and; (v) an overview of cancer treatments received among women, recently diagnosed with breast cancer in Northern Ireland. Individual studies identified within the first systematic review showed inconsistencies with respect to the association between ACEls/ARBs and cancer outcomes and following on from this, findings from two large population-based studies indicated little evidence of a beneficial association between ACEI or ARB use and breast and prostate cancer mortality outcomes, respectively, although a possible protective association was noted for ACEls and risk of prostate cancer mortality. Similarly, there was limited evidence to suggest an association between NSAID use and clinical outcomes from colorectal cancer, based on findings from the second systematic review and meta-analysis. Using data sources from within the Northern Ireland Cancer Registry, a retrospective population-based dataset of breast cancer patients, recently diagnosed in Northern Ireland was constructed. Cancer treatments were deemed appropriate and particular attention was given to adjuvant systemic therapies (including chemotherapy and hormone therapy). This dataset will enable future data linkage with dispensed medication records. Considering the frequency with which ACEls, ARBs, as well as NSAIDs are prescribed, further research into cancer outcomes with respect to these agents is warranted.
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Wolfman, Jessica Heather Kloss Jacqueline D. "Cancer specific stress and insomnia severity among breast cancer patients /". Philadelphia, Pa. : Drexel University, 2009. http://hdl.handle.net/1860/3024.
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Radu, Calin. "Optimising Radiotherapy in Rectal Cancer Patients". Doctoral thesis, Uppsala universitet, Enheten för onkologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-172531.
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Rectal cancer is the eight most common cancer diagnosis in Sweden in both men and women, with almost 2000 new cases per year. Radiotherapy, which is an important treatment modality for rectal cancer, has evolved during the past decades. Diagnostic tools have also improved, allowing better staging and offering information used to make well-founded decisions in multidisciplinary team conferences. In a retrospective study (n=46) with locally advanced rectal cancer (LARC) patients, unfit for chemoradiotherapy, patients were treated with short-course radiotherapy. Delayed surgery was done when possible. Radical surgery was possible in 89% of the patients who underwent surgery (80%). Grade IV diarrhoea affected three elderly patients. Target radiation volume should be reduced in elderly or metastatic patients. In a prospective study (n=68) with LARC patients, magnetic resonance imaging (MRI) and 2-18F-fluoro-2-D-deoxyglucose (FDG) positron emission tomography (PET) were used to determine if FDG-PET could provide extra treatment information. Information from FDG-PET changed the stage of 10 patients. Delineation with FDG-PET generally resulted in smaller target volumes than MRI only. Seven of the most advanced LARC patients in the above cohort were used for a methodological study to determine if dose escalation to peripheral, non-resectable regions was feasible. Simultaneous integrated boost plans with photons and protons were evaluated. While toxicity was acceptable in five patients with both protons and photons, two patients with very large tumours had unacceptable risk for intestinal toxicity regardless of modality. In the interim analysis of the Stockholm III Trial (n=303, studying radiotherapy-fractionation and timing of surgery in relation to radiotherapy) compliance was acceptable and severe acute toxicity was infrequent, irrespective of fractionation. Short-course radiotherapy with immediate surgery tended to give more postoperative complications, but only if surgery was delayed more than 10 days after the start of radiotherapy. Quality-of-life in the Stockholm III Trial was studied before, during and shortly after treatment using the EORTC QLQ-C30 and CR38 questionnaires. Surgery accounted for more adverse effects than radiotherapy in all groups. Postoperatively, the poorest quality-of-life was seen in patients given short-course radiotherapy followed by immediate surgery. No postoperative differences were seen between the two groups with delayed surgery.
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Nna, Emmanuel Okechukwu. "Molecular profiling of prostate cancer patients". Thesis, Cranfield University, 2009. http://dspace.lib.cranfield.ac.uk/handle/1826/4527.
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In the UK, more than 30 000 men are diagnosed annually with prostate cancer (PCa) and about 10 000 men die from it each year. Although several molecular markers have been associated with prostate cancer development and/ or progression, only few of them are used in diagnostic pathology. The current standard tests include serum PSA test, digital rectal examination and histology of prostate biopsy. Recently the PCA-3 molecular test was approved in the European Union, and it is now used in many laboratories. But these tests are not sufficient to molecularly characterise the behaviour of prostate cancer in many patients. Through extensive literature review, a panel of sixteen molecular markers were selected for further evaluation in prostate cancer cases. They included KLK2, KLK3, MCM2, MCM5, TP53, Bcl-2, CD44, CDH1, AURKA, AURKB, and AURKC; ESR , ESR , AR, FASN, TMPRSS2: ERG, and TMPRSS2:ETV1. The aim was to examine the link between development/progression of prostate cancer and the production of diagnostic/prognostic biomarkers. An in vitro model consisting of PC-3 and PNTIA, MDA PCa 2b prostate cell lines were used to investigate the influence of steroid hormones on these biomarkers using molecular and proteomic techniques. All the three cell lines expressed AR, ESR , ESR and PSA at mRNA and protein levels. The AR expressed in PC-3 and MDA PCA 2b cells was 60 kDa while the PNT1A expressed a 90 kDa AR protein. The ESR was over-expressed in the MDA PCA 2b cells, and was also significantly up-regulated by 17 oestradiol treatment. At a concentration of 4.92 and 33.96μM 17 oestradiol inhibited the growth of 10 to 50% of PNT1A cell line and increased the doubling time three folds. Although the PC-3 cells expressed AR, it was still androgen insensitive and could not produce PSA in culture supernatants. AR and PSA were up-regulated in PNT1A cells in response to testosterone and dihydrotesterone treatment but were reduced in response to 17 oestradiol and Hydrocortisone treatment. All the molecular markers except the TMPRSS2: ERG and TMPRSS2:ETV1 were expressed in the cell lines. The MCM2 and MCM5 were not differentially expressed in response to hormonal treatment. However, the Aurora kinases A, B and C were up-regulated in response to steroid modulation. The KLK2 was only up-regulated by the androgens. Three candidate control genes: ABL1, GUS and G6PD were also evaluated in the cell lines and clinical samples; the ABL1 gene emerged as the most stably expressed house keeping gene and was subsequently used in the normalization of real time PCR assays (RQ-PCR). Analysis of the sixteen biomarkers in prostate tissues and exfoliated urine cells of benign, prostate cancer and non-involved cases (n = 228) showed that seven of the molecular markers were significantly strongly associated with prostate cancer progression (P<0.05). The Aurora kinases A and B were consistently significantly over-expressed in prostate cancer cases. The CD44 was also over-expressed in prostate cancer, and was associated with Gleason score. The TMPRSS2 fusion genes were detected in 15.6% of the prostate cancer cases. The TP53 was also over-expressed in prostate cancer, and significantly associated with tumour grade. The ESR was over-expressed in prostate cancer, and was significantly associated with high tumour grade. This implied a proliferative role for the ESR in prostate cancer progression, because the ESR was not differentially expressed among the sample groups. Concomitantly, the AR was also over-expressed in same pattern with ESR . The combination of these biomarkers: AR, ESR , CD44, TP53, TMPRSS2 fusion genes, AURKA and AURKB could molecularly characterise most prostate cancers. Therefore 2 sets of pentaplex RQ-PCR assays including ABL1 for normalization would provide a cost-effective, flexibly high throughput assay for molecular grading of tissue sections in diagnostic pathology. In addition to the gene expression studies, the genetic variation in KLK2 gene was further investigated by direct DNA sequencing, pyrosequencing and TaqMan allelic discrimination assay. Two SNPs in the gene were found significantly associated with prostate diseases. The T/T allele of rs198977 predicted the presence of prostate cancer at biopsy and was associated with high tumour grade. The A/A variant of rs2664155 was also significantly associated with the presence of benign nodular hyperplasia. The combination of gene expression and genetic variation using real time PCR applications would provide an accurate, reproducible and cheap method for molecular profiling of prostate cancer patients. An exploratory study of organic volatiles in urine of one prostate cancer patient and eight BPH patients using thermal desorption GC-MS showed that Ethanethiol, Dimethyl sulfide, Propyn-1-ol acetate, Nitro-2-propanone, pentane, Hydrazine and Nitrous oxide were differentially over-expressed in the prostate cancer patient compared to the benign cases. Further studies would be required to rule out possible contamination and drug metabolites.
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Viganó, Antonio Angelo Luciano. "Survival predictors in advanced cancer patients". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0007/MQ28996.pdf.
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Persson, Christina. "Improved Nutritional Support in Cancer Patients". Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5218-3/.
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Blackwelder, Reid B. "Integrative Approaches to Patients with Cancer". Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etsu-works/6987.
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Vittatoe, Danielle S. y L. Lee Glenn. "Effects of Telemonitoring in Cancer Patients". Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/7473.
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Motenko, Jill Swartwout. "The Spiritual Quests of Cancer Patients". Antioch University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=antioch1329323769.
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Allen, Denise M. "Future orientation of adolescent cancer patients /". The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487758178237076.
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Rattican, Debra. "Symptom Clusters in Lung Cancer Patients". VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/352.
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SYMPTOM CLUSTERS IN LUNG CANCER PATIENTS By Debra Rattican, PhD, RN A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth University, 2012 Major Director: Debra E. Lyon, PhD. Professor and Chair Family and Community Health Nursing The purpose of the study was to examine selected relationships among symptoms common to individuals with lung cancer. The specific aims were: 1) To examine the relationship between the symptoms of dyspnea and anxiety in patients with lung cancer. 2) To examine the relationships among the symptoms of dyspnea, anxiety, and symptom cluster components (depressive symptoms, fatigue, pain) in patients with lung cancer. 3) To examine the correlation between functional ability and quality of life in patients with lung cancer. 4) To explore the relationships among the symptoms of dyspnea, anxiety, and symptom cluster components (depressive symptoms, fatigue, pain) in patients with lung cancer and patients’ functional ability. 5) To explore the relationships among the symptoms of dyspnea, anxiety, and symptom cluster components (depressive symptoms, fatigue, pain) in patients with lung cancer and patients’ quality of life. Data were gathered through online survey and analyzed using descriptive, correlation, principal component analysis, exploratory factor analysis, and forward stepwise regression techniques. A strong positive correlation was found between dyspnea and anxiety (both anxiety in general and anxiety at the time the survey was completed. While results of this study cannot provide conclusive evidence of the existence of a symptom cluster composed of depressive symptoms, fatigue, and pain, the results are consistent with other studies in this area. Significant positive correlations among these three symptoms indicate that this is a possible symptom cluster experienced by lung cancer patients in general. This study provides preliminary data on how these symptoms are related and how they affect functional ability, or the ability to perform routine activities of daily living (ADLS) and instrumental activities of daily living (IADLS), and quality of life in patients with lung cancer. Further study is needed on to better understand the symptom experience of these individuals in order to develop robust interventions targeting effective symptom management.
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Pietrucin-Materek, Marta. "Patients' preferences for cancer follow-up". Thesis, University of Aberdeen, 2014. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=223919.
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Introduction As a result of the growing and ageing population in developed countries, improved cancer detection and advances in cancer treatments, there are more people living with cancer for longer. The rising number of cancer survivors and increasing demand for oncology services, has sparked interest in alternative ways of delivering cancer follow-up care. Although a number of alternative cancer follow-up strategies have been developed, information about the relative importance of different characteristics of follow-up and how people trade between these characteristics is still limited. Aims and objectives The overall aim of the thesis was to understand what characteristics (called attributes and levels) of cancer follow-up services are important to survivors of cutaneous melanoma, breast, prostate and colorectal cancer; whether people make trade-offs between these characteristics; and whether survivors of different cancers with different personal characteristics express different preferences for cancer follow-up care. The aim was met by a number of objectives: •To conduct a review of the literature to gather information about characteristics of follow-up that are important to people. • To conduct semi-structured qualitative interviews with cancer survivors living in North East Scotland, to determine their views of current care and preferences for future cancer follow-up. • Based on the findings from the literature and semi-structured interviews, to determine characteristics (attributes and levels) of cancer follow-up services for inclusion in a discrete choice experiment. • To develop and carry out a discrete choice experiment to establish the relative importance of a number of attributes of cancer follow-up amongst cancer survivors treated and followed up for cutaneous melanoma, breast, prostate and colorectal cancer.
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Dasch, Kimberly B. "Affective differentiation in breast cancer patients". Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 70 p, 2009. http://proquest.umi.com/pqdweb?did=1885670961&sid=7&Fmt=2&clientId=8331&RQT=309&VName=PQD.
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Ku, Wai-yin Ellen. "An exploration of the communication needs of cancer patients". Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22078988.
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Zunkel, Gretchen M. "Couple processes as a context for breast cancer recovery : doing everything we can /". Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/7223.
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Casey, Susan Marie. "Metastatic recurrent breast cancer : the couples' experience with role changes /". Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/7253.
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Knecht, Vicky Marie. "PATIENTS WITH GYNECOLOGICAL CANCER: COMPARISON OF LEARNING NEEDS OF PATIENTS AND THEIR SIGNIFICANT OTHERS". Thesis, The University of Arizona, 1985. http://hdl.handle.net/10150/292091.
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Stevens, Victoria E. "Personality type and ways of coping : a study of female spouses of post myocardial infarction patients /". Access Digital Full Text version, 1992. http://pocketknowledge.tc.columbia.edu/home.php/bybib/11228313.
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Thesis (Ed.D.)--Teachers College, Columbia University, 1992.Includes tables. Typescript; issued also on microfilm. Sponsor: Marilyn Rawnsley. Dissertation Committee: John P. Allegrante. Includes bibliographical references (leaves 135-141).
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De, Klerk Jacoba Elizabeth. "Hypnotherapeutic ego strengthening with coronary artery bypass surgery patients and their spouses / acoba Elizabeth de Klerk". Thesis, North-West University, 2003. http://hdl.handle.net/10394/441.
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Coronary artery bypass surgery (CABS) is highly stressful for couples, since comorbid
anxiety and depression are most commonly reported and hence most researched pre- and
postoperative emotional states. Thus, patients' psychological well-being may contribute
more to the level of disability than their physical impairment. Despite this extremely
stressful process, psychological preparation is ironically often neglected in CABS couples.
The primary aim of the study was to examine the feasibility of hypnotherapeutic ego
strengthening (HES) to enhance the ability of CABS couples' to cope with psychological
distress associated with hospitalisation and surgery. Secondary aims were to determine the
contribution of HES in reducing anxiety and depression, as well as enhancing and
maintaining ego strength, quality of life and dispositional optimism in CABS patients and
spouses.
An overview of coronary heart disease (CHD), risk factors involved, psychological aspects
concomitant to CABS (specifically anxiety and depression) and a conceptualisation of
HES according to the relevant literature, preceded the empirical study.
The experimental design consisted of a two-group, pre-post-follow-up assessment design.
A sample of fifty married, male patients admitted to Unitas Hospital in Pretoria with a first,
uncomplicated CABS was randomly assigned, together with their spouses, to an
experimental- (n = 25) and control group (n = 25). Informed consent was obtained for all
project participants. Thus, both groups consisted of twenty-five patients and spouses. To
test the hypotheses, experimental patients and spouses were required to participate in the
HES intervention.
Respondents completed the Beck Depression Inventory (BDI-II) (Beck, Steer, & Brown,
1995). Profile of Mood States (POMS) (McNair, Lorr & Doppleman, 1992), Epstein and
O'Brien Ego Strength Scale (1982), Quality of Life Inventory (QOLI) (Frisch, 1994) as
well as the Life Orientation Test (LOT) (Scheier & Carver, 1985). Test administration of
couples occurred preoperatively, on the day of discharge, and at six-week follow-up.
Before commencing the intervention, group comparability was confirmed by means of the
t-test for independent groups. At programme completion the significance of differences
within and between groups was determined by means of t-tests. Statistically significant
p-values were subjected to Cohen's d statistic to determine the practical significance of the
findings. A confidence interval of 99% determined the values of the differences between
the postoperative and follow-up findings.
Results confirmed that the HES intervention significantly reduced postoperative anxiety
and depression levels in experimental CABS patients and spouses, which was maintained
at follow-up. No change was observed among control group patients and spouses.
Moreover, the HES intervention significantly improved and maintained postoperative ego
strength, quality of life and dispositional optimism in experimental CABS couples. The
overall outcome of the control patients and spouses revealed a decreasing trend with regard
to dispositional optimism and quality of life. Qualitative responses largely confirmed
quantitative indications of reduced comorbidity and enhanced psychological well-being
among experimental participants.
Despite design limitations, the results confirmed that HES enhanced CABS couples' inner
resources and attenuated concomitant negative mood states. Thus, it was concluded that
HES played a meaningful role in the preparation and care of CABS couples by reducing
comorbidity and improving their psychological well-being. Finally, recommendations for
further studies were made.Thesis (Ph.D. (Psychology))--North-West University, Potchefstroom Campus, 2004.