Literatura académica sobre el tema "Souris – Reproduction (biologie) – Régulation"
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Artículos de revistas sobre el tema "Souris – Reproduction (biologie) – Régulation":
Labbé, Morgane. "La régulation des naissances dans la Pologne des années 1930. Une providence (ou la nature) raisonnée (Tome 145, 7e Série, n°1-2, (2024))". Revue de Synthèse, 22 de noviembre de 2023, 1–48. http://dx.doi.org/10.1163/19552343-14234046.
Tesis sobre el tema "Souris – Reproduction (biologie) – Régulation":
Trouillet, Anne-Charlotte. "Rôle des mécanismes de signalisation olfactive impliquant Gai2 dans le contrôle des comportements socio-sexuels". Electronic Thesis or Diss., Tours, 2021. http://www.theses.fr/2021TOUR4018.
In most mammals, the olfactory system drives socio-sexual behaviors through the detection of chemosensory information. Sensory neurons of the olfactory system detect these signals through dedicated G protein-coupled receptors, each expressed by a single ensemble of neurons. Chemosignals relevant for social communication are mainly sensed by the vomeronasal organ in which at least two populations of receptor cells detect pheromones through two families of G-protein-coupled receptors, V1Rs and V2Rs. The binding of ligands to the receptor (V1R or V2R) has been proposed to activate the corresponding G protein, Gai2 and Gao, respectively. Gao-expressing neurons have been shown to detect peptides and proteins modulating several social behaviors. Genetic and behavioral studies on mice also point to a potential role of Gai2-expressing neurons as transducers of the olfactory information controlling reproductive physiology and behaviors. However, the exact contribution of this signaling pathway remains elusive. Therefore, the main goal of this project is to determine how socio-sexual behaviors are controlled by the olfactory system, particularly by the V1R-Gai2-expressing neurons of the vomeronasal organ.To address this point, we used the Cre-lox system to generate a conditional knockout mouse in which the deletion of Gai2 gene is restricted to olfactory sensory neurons. First, we evaluated the functional role of Gai2 in the process of VSNs signal transduction using live-cell calcium imaging experiments. We first established that Gai2 is necessary for the detection of small organic molecules and sulfated steroids in V1Rs-expressing VSNs. Second, we investigated the role of Gai2/V1Rs-expressing VSNs in displaying reproductive and social behaviors. We tested sexual, parental, and aggressive behaviors of male and female mice deficient for Gai2 and identified brain regions transforming the olfactory information into a behavioral decision. We observed an influence of Gai2-expressing VSNs in a sex-dependent manner with distinctive traits for each behavior. We found that the deletion of Gai2 in VSNs played a central role in male aggressive behavior by increasing territorial aggression and reducing infant-directed aggression. However, female aggression remained unaltered in the absence of Gai2. Parenting was also differentially affected by Gai2 deletion in each sex, activated in males and inhibited in females. Further, social experience changed the implication of Gai2 vomeronasal signaling in female sexual behavior, while in males, Gai2-deletion had no effect on sexual behavior before or after experience. Last, we identified a new role of Gai2-expressing VSNs in avoidance behaviors mediated by predators and sick-conspecifics aversive olfactory cues.All species continuously integrate environmental information and adapt their responses accordingly. This project aims to shed light on neural mechanisms underlying the processing of olfactory chemosignals in order to understand how peripheral olfactory inputs interact with neural centers controlling the behavioral responses. Understanding these mechanisms is of broad relevance and may lead to new insights in the comprehension of behavioral disorders and the development of new breeding strategies in domestic animals
Caron, Emilie. "Leptine et régulation hypothalamique de la fonction de reproduction chez la souris : sites d'action et influence de la nutrition postnatale". Lille 2, 2006. http://www.theses.fr/2006LIL2S052.
Badro, Danielle. "Identification de nouvelles cibles de WT1 au cours de la néphrogenèse précoce et analyses fonctionnelles chez la souris". Nice, 2009. http://www.theses.fr/2009NICE4119.
WT1 encodes a transcription factor and is mutated in a subset of Wilms’ tumors in children. Instead of developing motors, Wt1-/- mouse embryos suffer from renal agenesis due to apoptosis of the tissue, clearly demonstrating the complexity of WT1 functions in vivo. In this study we took an unbiased approach by performing DNA microarray studies on renal tissues isolated from Wt1-/- and Wt1-/- embryos at E10. 25. Three genes with reduced expressions were selected for further studies : Rspondin1, Fgf10, and Fgf20. RSPO1 is a secreted positive modulator of the WNT/β-catenin signalling pathway. In the mouse embryonic kidney Wt1 and Rspo1 expressions highly overlap. The combination of reporter transgenic embryos and in vitro experiments point to a very complex regulation of Rspo1, with evolutionary conserved elements scattered over more than 20kb upstream of the transcription start site. In particular, we isolated a 750bp region driving Rspo1 expression in the mouse neural tissues. Fibroblast growth factors FGF10 and FGF20 are secreted molecules implicated in the lacrimoauriculodentodigital syndrome and Parkinson’s disease, respectively. We have addressed potential roles of FGF10 and FGF20 in the renal phenotype of Wt1-/- embryos. In vitro cultures of wildtype urogenital ridges (UGR) in media supplemented with FGF10/20 led to ectopic production of UBs. Moreover, UGRs from Wt1-/- mice showed a partial rescue of the phenotype by forming a UB. Taken together we have identified novel genes that are under control of WT1 and that may play key roles during kidney development. Future functional analysis will better assess their roles and involvement in the complex phenotype of Wt1-/- mice
Watrin, Marguerite. "Régulation de l'expression génique par formation de complexes boucle-boucles ARN : application de la technique de SELEX génomique aux interactions ARN/ ARN". Bordeaux 2, 2008. http://www.theses.fr/2008BOR21548.
RNA does not only play a role in the genetic information transfer between a gene and his protein. As mRNA, tRNA and rRNA are involved in protein synthesis. MiRNA, snRNA, snoRNA and other ncRNA are involved in the regulation of numerous biological processes such as plasmid replication, conjugation, transcription, translation, splicing and posttranscriptional modifications. RNA are able to form stem-loop structures, to interact via their loops with nucleic partners and to form loop-loop complexes so called kissing complexes. RNAI/RNAII kissing complexes enables the regulation of ColE1 plasmid replication in E. Coli. An RNA hairpin (aptamer R-0624) has been selected against the TAR element located at the end of the 5' UTR of the human immunodeficiency virus HIV-1 RNA. The artificial R-0624/TAR kissing complex inhibits the transactivation of the viral transcription. We identified RNA hairpins derived from the human genome which are able to generate kissing complexes with TAR or RNA hairpins targets containing RNGG, RYRY or YUNR loop sequences. Those kissing complexes could be responsible for natural or artificial regulations of human genes. In this work, genomic SELEX (Systematic Evolution of Liganfs by Exponential enrichment) has been carried for the 1rst time for fishing RNA/RNA interactions and directed against target RNA libraries
Rajabi, Maham Hassan. "Phylogéographie des souris du complexe Mus musculus en Iran : coalescence mitochondriale et diversité du chromosome Y". Montpellier 2, 2007. http://www.theses.fr/2007MON20077.
Jouve, Pesce Caroline. "Analyse de la mise en place et de la régulation de l'horloge de segmentation chez le poulet et la souris". Aix-Marseille 2, 2000. http://www.theses.fr/2000AIX22096.
Palma, Rigo Kesia. "Implication du récepteur AT1 central dans la régulation de la pression artérielle de la souris". Paris 5, 2011. http://www.theses.fr/2011PA05P606.
The central regulation of arterial pressure (AP) involves activation of angiotensin II receptors type 1 (AT1R) in specific brain area of the hypothalamus and brainstem. The thesis studies involve modulation of brain AT1R using genetic and hypertensive mice combined with a telemetry system to record AP. The mouse model expressing a gain of function of the AT1R subtype A (AT1AMUT) showed high AP and reduced cardiac baroreflex sensitivity, but a normal circadian cardiovascular rhythm. The role of AT1R in the AP level of the genetic hypertensive mouse (BPH/2J) was examined and found to be similar to normotensive mice. However, in BPH/2J mice AT1R are important for the cardiac baroreflex and pressor responses to stress. These findings led to a targeted analyse of this receptor in the caudal ventrolateral medulla (CVLM) which is known for its role in baroreflex control. In the mice lacking the gene coding the AT1R, the expression of its subtype A, obtained by viral transgenesis in the CVLM, reduced the pressor response to an emotional stress and reduced the baroreflex sensitivity during the day period. These findings indicate the importance of the brain renin angiotensin system through activation of AT1R which modulates the sympathetic contribution to blood pressure control at a number of levels within the central nervous system. Of particular importance is the modulation of baroreflex control and the sympatho-inhibitory actions during emotional stress both of which occur within the ventral medulla
Ganem, Guila. "Commensalisme, fonction corticosurrénalienne et évolution chromosomique chez la souris domestique". Montpellier 2, 1991. http://www.theses.fr/1991MON20053.
Mouzat, Kevin. "Etude du rôle des récepteurs nucléaires des oxystérols LXR alpha et LXR bêta dans la physiologie de la reproduction chez la souris femelle". Phd thesis, Clermont-Ferrand 2, 2007. http://www.theses.fr/2007CLF21802.
Jacquart, Thierry. "Structure génétique et phylogénie intraspécifique chez la souris sauvage Mus spretus Lataste : distribution spatiale du polymorphisme des gènes nucléaires de structure et de l'ADN mitochondrial". Montpellier 2, 1986. http://www.theses.fr/1986MON20053.
Libros sobre el tema "Souris – Reproduction (biologie) – Régulation":
Blank, Robert H. Regulating reproduction. New York: Columbia University Press, 1990.
Blank, Robert H. Regulating reproduction. New York: Columbia U.P., 1990.
Bogue, Donald J. Fertility, family planning, HIV/AIDS, and reproductive health: With emphasis on the Third World. Chicago: Social Development Center, 2004.
19, Article. Right to know: Human rights and access to reproductive health information. London: Article 19, 1995.