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Literatura académica sobre el tema "Sources MIR"

Autor: Grafiati

Publicado: 25 de mayo de 2024

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Artículos de revistas sobre el tema "Sources MIR"

Chen, H. y M. A. Garrett. "Searching for Kardashev Type III civilisations from high q-value sources in the LoTSS-DR1 value-added catalogue". Monthly Notices of the Royal Astronomical Society 507, n.º 3 (4 de agosto de 2021): 3761–70. http://dx.doi.org/10.1093/mnras/stab2207.

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ABSTRACT Kardashev Type III civilisations have by definition energy requirements that are likely to generate strong excess emission in the mid-infrared (MIR) that is associated with the waste heat they generate. For those civilisations that capture starlight via Dyson sphere like constructions, the Optical to MIR flux ratio of the host galaxies is also expected to be unusually low. Since a wide range of galaxy types adhere to the infrared-radio correlation (IRC), galaxies hosting Type III civilisations should also strongly deviate from this relation. Radio data can therefore play a crucial role in breaking the degeneracy between the effects of dust obscuration in a galaxy and the signature of an energy-intensive civilisation. We have used the newly released LoTSS-DR1 value-added catalogue to create a sample of 16 367 z < 0.2 sources with radio and MIR flux densities, optical photometry and (photometric) redshifts. We calculated the IRC parameter $q^{{\rm 22~\mu m}}_{{\rm 150~MHz}}$ = log(S150 MHz/$S_{22~{\rm \mu m}}$) and identified 21 sources with exceptionally high values of $q^{{\rm 22~\mu m}}_{{\rm 150~MHz}}$, an indication of MIR emission enhanced by a factor of ∼10. Out of the 21 high q-value sources, 4 sources have very red MIR colours, and appear to have relatively low optical/MIR ratios. Two of the four sources are not well known in the literature, they are considered as potential hosts of Type III civilisations. These sources deserve further study and investigation. Finally, we note that extending our analysis to the full LoTSS survey area can place very strong constraints on the incidence of Type III civilisations in the Universe.

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Martinez, Cristina A., Jordi Roca, Manuel Alvarez-Rodriguez y Heriberto Rodriguez-Martinez. "miRNA-Profiling in Ejaculated and Epididymal Pig Spermatozoa and Their Relation to Fertility after Artificial Insemination". Biology 11, n.º 2 (1 de febrero de 2022): 236. http://dx.doi.org/10.3390/biology11020236.

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MicroRNAs (miRNAs) are short non-coding RNAs (20–25 nucleotides in length) capable of regulating gene expression by binding -fully or partially- to the 3’-UTR of target messenger RNA (mRNA). To date, several studies have investigated the role of sperm miRNAs in spermatogenesis and their remaining presence toward fertilization and early embryo development. However, little is known about the miRNA cargo in the different sperm sources and their possible implications in boar fertility. Here, we characterized the differential abundance of miRNAs in spermatozoa from the terminal segment of the epididymis and three different fractions of the pig ejaculate (sperm-peak, sperm-rich, and post-sperm rich) comparing breeding boars with higher (HF) and lower (LF) fertility after artificial insemination (AI) using high-output small RNA sequencing. We identified five sperm miRNAs that, to our knowledge, have not been previously reported in pigs (mir-10386, mir-10390, mir-6516, mir-9788-1, and mir-9788-2). Additionally, four miRNAs (mir-1285, mir-92a, mir-34c, mir-30), were differentially expressed among spermatozoa sourced from ejaculate fractions and the cauda epididymis, and also different abundance was found between HF and LF groups in mir-182, mir-1285, mir-191, and mir-96. These miRNAs target genes with key roles in fertility, sperm survival, immune tolerance, or cell cycle regulation, among others. Linking the current findings with the expression of specific sperm proteins would help predict fertility in future AI-sires.

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Zhang, Hong-Ping, Bin Zhao, Rong-Ze Ma, Zhen-Rui Li y Peng-Fei Wang. "Numerical simulation of coherent mid-infrared supercontinuum generation based on carbon chloride core tapered photonic crystal fibers". Laser Physics 33, n.º 12 (30 de octubre de 2023): 125401. http://dx.doi.org/10.1088/1555-6611/ad04c4.

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Abstract We numerically studied coherent mid-infrared (MIR) supercontinuum (SC) generated by filling carbon chloride (CCl4, C2Cl4) into the tapered photonic crystal fiber (PCF). The mechanism involves nonlinear soliton compression, Raman soliton self-frequency shift and dispersive wave generated in a carbon chloride core tapered PCF pumped by a 1.98 μm femtosecond laser. Numerical solution of the generalized nonlinear Schrodinger equation shows that 1.15–5.5 μm (CCl4-core tapered PCF) and 1.15–5.7 μm (C2Cl4-core tapered PCF) coherent MIR-SC sources can be realized. Our results show that the above liquid-core tapered PCFs are promising nonlinear media for constructing broadband coherent MIR-SC light sources.

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Medina Villaamil, V., M. Blanco Calvo, S. M. Díaz Prado, S. Antolín Novoa, L. Calvo Martínez, I. Santamarina Caínzos, M. Haz Conde, L. M. Antón Aparicio y M. Valladares-Ayerbes. "MicroRNA for circulating tumor cells detection in breast cancer: In silico and in vitro analysis". Journal of Clinical Oncology 27, n.º 15_suppl (20 de mayo de 2009): e22027-e22027. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e22027.

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e22027 Background: Detection of circulating tumor cells (CTC) may provide diagnostic and prognostic information in breast cancer (bc) patients. Deregulation of microRNAs (miRNAs) is frequent in tumors, including breast cancer. It is suggested miRNAs play a role in tumor progression. We hypothesized that miRNAs may constitute a promising new class of cancer biomarkers for CTC detection. Our objective has been to identify miRNAs potentially useful for CTC detection. Methods: Phase I preclinical study was performed by means of computational tools for miRNAs profiling including MIRGATOR, MIRBASE, SMIRNAdb, GeneHUB-GEPIS, MICRORNA.ORG, and MIRNAMAP. In silico data were used to identify and prioritize miRNAs highly expressed in breast cancer, but absent in hematopoietic-derived sources. Selected miRNAs were evaluated by means of qRT-PCR in breast cancer and Hematopoietic cell lines, normal blood, and blood from breast cancer patients. Results: Computational tools identify a set of miRNAs highly expressed in breast cancer sources in relation to hematopoietic samples. Among these were miR-141, miR-200c, miR-196a, miR-203, miR-200a, miR-200b, miR-32, miR-375, miR-31, miR-193a, and miR-205. For instance, relative expression of miR-32 was 104 higher in bc cell lines (N= 5) than in normal PB (N = 19) using qRT-PCR. In a preliminary analysis of PB from bc patients (stage IV) higher relative expression levels for selected miRNAs were found comparing with age-matched controls’ blood. Conclusions: Our results suggest that miRNA bioinformatic approach is a useful high-throughput method to select bc-associated miRNAS. The selected miRNAs should be further evaluated for their potential as markers for CTC detection. We next investigate if blood miRNA profile could predict tumor progression and survival. Supported by grants PI06/1541 and PI07/0477 from Fondo de Investigaciones Sanitarias (FIS), Instituto de Salud Carlos III. No significant financial relationships to disclose.

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Mustafin, R. N. "Relationship of MicroRNAs with Transposable Elements in the Type 1 Diabetes Development". Russian Archives of Internal Medicine 13, n.º 6 (12 de enero de 2024): 413–21. http://dx.doi.org/10.20514/2226-6704-2023-13-6-413-421.

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The review article describes the involvement of epigenetic factors in type 1 diabetes mellitus (T1DM) etiopathogenesis. The disease is characterized by changes in expression of microRNAs that affect the transcription of genes involved in autoimmune reactions, destruction of beta cells and insulin production. However, the cause of the observed epigenetic changes is still unclear. In evolution, the sources of microRNA genes are transposable elements, which occupy up to 45 % of the entire human DNA sequence and are drivers of epigenetic regulation in ontogenesis. They are sources of transcription factor sequences and binding sites for them. Features of the genome distribution of transposable elements can cause changes in the number of 5’VNTR (variable number of tandem repeats) — repeats of insulin promoter region and HERV insertions into HLA genes, which affects their expression. Therefore, I assume that the cause of the development of type 1 diabetes mellitus may be an imbalance in transcription activation of transposons, which contributes to changes in the expression of specific microRNAs and protein-coding genes, and also contributes to autoimmune response development. Triggers for this may be individual features of genome distribution of transposons, viral infections and stress. An analysis of the scientific literature confirms my proposed mechanisms for T1DM development, since the global role of retroelements in hormonal regulation, the sensitivity of transposable elements to exogenous viral infections and stress, and HERV-W expression of the majority of patients with T1DM with activation of the autoimmune response have been proven. Analysis of the MDTE DB (miRNAs derived from transposable elements database) database showed the transposon origin of 12 T1DM-associated microRNAs (miR-192, miR-224, miR-31, miR-320c, miR-326, miR-340, miR-342, miR-44661, miR-548c, miR-652, miR-95), the use of which can become the basis for targeted therapy for T1DM.

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Metcalfe, Leo, B. Mcbreen, J. P. Kneib y B. Altieri. "Gravitational Lensing and Deep Infrared Surveys". Symposium - International Astronomical Union 204 (2001): 217–32. http://dx.doi.org/10.1017/s0074180900226119.

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ISO's infrared camera was used to make deep mid-infrared (MIR) images through three gravitationally lensing clusters of galaxies. Observations were made at 7 μm and 15 μm covering more than 50 square arcminutes, with the lensing increasing the sensitivity to background sources significantly.A large number of MIR sources were detected behind the lenses and provide source counts, corrected for cluster contamination and lensing distortion effects, which exceed by a factor of 10 the expectation from local counts assuming a no-evolution model. The results are consistent with larger-area surveys and the detected population resolves a substantial fraction (of order 60%) of the background MIR radiation intensity into discrete sources.We discuss the evidence, in large part derived from lensing cluster observations, for overlap of the ISO 15 μm faint galaxy population with the 850 μm submillimetre and the 0.5 to 7 keV X-ray populations. We find that the ISO data shows substantial overlap with both the submillimetre and the X-ray source populations, with roughly 25% of ISO sources being detected at submillimetre wavelengths and a significant number of Chandra X-ray sources being detected in the ISO data.

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Petroušková, Patrícia, Nikola Hudáková, Marcela Maloveská, Filip Humeník y Dasa Cizkova. "Non-Exosomal and Exosome-Derived miRNAs as Promising Biomarkers in Canine Mammary Cancer". Life 12, n.º 4 (1 de abril de 2022): 524. http://dx.doi.org/10.3390/life12040524.

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Canine mammary cancer (CMC), similar to human breast cancer (HBC) in many aspects, is the most common neoplasm associated with significant mortality in female dogs. Due to the limited therapy options, biomarkers are highly desirable for early clinical diagnosis or cancer progression monitoring. Since the discovery of microRNAs (miRNAs or miRs) as post-transcriptional gene regulators, they have become attractive biomarkers in oncological research. Except for intracellular miRNAs and cell-free miRNAs, exosome-derived miRNAs (exomiRs) have drawn much attention in recent years as biomarkers for cancer detection. Analysis of exosomes represents a non-invasive, pain-free, time- and money-saving alternative to conventional tissue biopsy. The purpose of this review is to provide a summary of miRNAs that come from non-exosomal sources (canine mammary tumor, mammary tumor cell lines or canine blood serum) and from exosomes as promising biomarkers of CMC based on the current literature. As is discussed, some of the miRNAs postulated as diagnostic or prognostic biomarkers in CMC were also altered in HBC (such as miR-21, miR-29b, miR-141, miR-429, miR-200c, miR-497, miR-210, miR-96, miR-18a, miR19b, miR-20b, miR-93, miR-101, miR-105a, miR-130a, miR-200c, miR-340, miR-486), which may be considered as potential disease-specific biomarkers in both CMC and HBC.

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Eckart, A., J. Moultaka, T. Viehmann, C. Straubmeier, N. Mouawad, R. Genzel, T. Ott y R. Sch�del. "New MIR Excess Sources north of the IRS 13 Complex". Astronomische Nachrichten 324, S1 (septiembre de 2003): 521–26. http://dx.doi.org/10.1002/asna.200385059.

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Lewellis, Stephen W., Danielle Nagelberg, Abhi Subedi, Alison Staton, Michelle LeBlanc, Antonio Giraldez y Holger Knaut. "Precise SDF1-mediated cell guidance is achieved through ligand clearance and microRNA-mediated decay". Journal of Cell Biology 200, n.º 3 (4 de febrero de 2013): 337–55. http://dx.doi.org/10.1083/jcb.201207099.

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During animal development, SDF1 simultaneously guides various cell types to different targets. As many targets are in close proximity to one another, it is unclear how the system avoids mistargeting. Zebrafish trigeminal sensory neurons express the SDF1 receptor Cxcr4b and encounter multiple SDF1 sources during migration, but ignore all but the correct one. We show that miR-430 and Cxcr7b regulation of SDF1a are required for precise guidance. In the absence of miR-430 or Cxcr7b, neurons responded to ectopic SDF1a sources along their route and did not reach their target. This was due to a failure to clear SDF1a transcript and protein from sites of expression that the migrating neurons had already passed. Our findings suggest an “attractive path” model in which migrating cells closely follow a dynamic SDF1a source that is refined on a transcript and protein level by miR-430 and Cxcr7b, respectively.

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Pikir, Budi Susetio, Andrianto Andrianto, I. Gde Rurus Suryawan, Hanestya Oky Hermawan, Dian Paramita Kartikasari y Primasitha Maharany Harsoyo. "microRNA-1 Induces Transdifferentiation of Peripheral Blood CD34+ Cells into Cardiomyocytes-like Cells". Indonesian Biomedical Journal 14, n.º 3 (8 de septiembre de 2022): 269–75. http://dx.doi.org/10.18585/inabj.v14i3.1888.

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BACKGROUND: Transdifferentiation is a method to provide cells sources for cellular cardiomyoplasty. CD34+ cells are potential cells sources because these cells can differentiate into cardiomyocytes through several mechanisms. MicroRNA (miR-1) is known to have the ability to inhibit the expression of histone deacetylase 4 (HDAC4). HDAC4 is a gene that essentially contributes in cardiomyocytes differentiation. However, the study reporting an evidence that miR-1 can induce transdifferentiation of CD34+ peripheral blood cells into mature cardiomyocytes is limited.METHODS: CD34+ cells were taken from peripheral blood and isolated using a magnetic-activated cell sorting (MACS) method in vitro. Mature mimics of miR-1 were transfected into isolated CD34+ cells and then incubated for 48 hours for quantification of HDAC4 mRNA using reverse transcription-quantitative polymerase chain reaction (RT-qPCR). On the fifth day after miR-1 transfection, cardiomyocyte-like cells were identified based on their morphology and cardiac troponin expression using immunocytochemistry.RESULTS: Transfection of miR-1 in CD34+ isolated cells decreased HDAC4 gene expression by -0.54 fold at second day and caused a significant increase in percentage of cardiac troponin positive cells (median: 31.34; p<0.05) at fifth-day post-transfection. The efficiency of transdifferentiation was 32%. The miR-1 transfection had a significant negative relationship with HDAC4 gene expression (B=-1.000; p=0.001). HDAC4 gene expression had a negative and significant relationship with the percentage of cardiac troponin-positive cells (B=-0.701; p=0.001).CONCLUSION: This study suggests that miR-1 can induce transdifferentiation of peripheral blood CD34+ cells into cardiomyocytes-like cells by decreasing HDAC4 gene expression.KEYWORDS: transdifferentiation, microRNA-1, CD34, cardiomyocyte, HDAC4

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Tesis sobre el tema "Sources MIR"

Meseguer, Brocal Gabriel. "Multimodal analysis : informed content estimation and audio source separation". Electronic Thesis or Diss., Sorbonne université, 2020. http://www.theses.fr/2020SORUS111.

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Cette thèse propose l'étude de l'apprentissage multimodal dans le contexte de signaux musicaux. Tout au long de ce manuscrit, nous nous concentrerons sur l'interaction entre les signaux audio et les informations textuelles. Parmi les nombreuses sources de texte liées à la musique qui peuvent être utilisées (par exemple les critiques, les métadonnées ou les commentaires des réseaux sociaux), nous nous concentrerons sur les paroles. La voix chantée relie directement le signal audio et les informations textuelles d'une manière unique, combinant mélodie et paroles où une dimension linguistique complète l'abstraction des instruments de musique. Notre étude se focalise sur l'interaction audio et paroles pour cibler la séparation de sources et l'estimation de contenu informé. Les stimuli du monde réel sont produits par des phénomènes complexes et leur interaction constante dans divers domaines. Notre compréhension apprend des abstractions utiles qui fusionnent différentes modalités en une représentation conjointe. L'apprentissage multimodal décrit des méthodes qui analysent les phénomènes de différentes modalités et leur interaction afin de s'attaquer à des tâches complexes. Il en résulte des représentations meilleures et plus riches qui améliorent les performances des méthodes d'apprentissage automatique actuelles. Pour développer notre analyse multimodale, nous devons d'abord remédier au manque de données contenant une voix chantée avec des paroles alignées. Ces données sont obligatoires pour développer nos idées. Par conséquent, nous étudierons comment créer une telle base de données en exploitant automatiquement les ressources du World Wide Web. La création de ce type de base de données est un défi en soi qui soulève de nombreuses questions de recherche. Nous travaillons constamment avec le paradoxe classique de la `` poule ou de l'œuf '': l'acquisition et le nettoyage de ces données nécessitent des modèles précis, mais il est difficile de former des modèles sans données. Nous proposons d'utiliser le paradigme enseignant-élève pour développer une méthode où la création de bases de données et l'apprentissage de modèles ne sont pas considérés comme des tâches indépendantes mais plutôt comme des efforts complémentaires. Dans ce processus, les paroles et les annotations non-expertes de karaoké décrivent les paroles comme une séquence de notes alignées sur le temps avec leurs informations textuelles associées. Nous lions ensuite chaque annotation à l'audio correct et alignons globalement les annotations dessus
This dissertation proposes the study of multimodal learning in the context of musical signals. Throughout, we focus on the interaction between audio signals and text information. Among the many text sources related to music that can be used (e.g. reviews, metadata, or social network feedback), we concentrate on lyrics. The singing voice directly connects the audio signal and the text information in a unique way, combining melody and lyrics where a linguistic dimension complements the abstraction of musical instruments. Our study focuses on the audio and lyrics interaction for targeting source separation and informed content estimation. Real-world stimuli are produced by complex phenomena and their constant interaction in various domains. Our understanding learns useful abstractions that fuse different modalities into a joint representation. Multimodal learning describes methods that analyse phenomena from different modalities and their interaction in order to tackle complex tasks. This results in better and richer representations that improve the performance of the current machine learning methods. To develop our multimodal analysis, we need first to address the lack of data containing singing voice with aligned lyrics. This data is mandatory to develop our ideas. Therefore, we investigate how to create such a dataset automatically leveraging resources from the World Wide Web. Creating this type of dataset is a challenge in itself that raises many research questions. We are constantly working with the classic ``chicken or the egg'' problem: acquiring and cleaning this data requires accurate models, but it is difficult to train models without data. We propose to use the teacher-student paradigm to develop a method where dataset creation and model learning are not seen as independent tasks but rather as complementary efforts. In this process, non-expert karaoke time-aligned lyrics and notes describe the lyrics as a sequence of time-aligned notes with their associated textual information. We then link each annotation to the correct audio and globally align the annotations to it. For this purpose, we use the normalized cross-correlation between the voice annotation sequence and the singing voice probability vector automatically, which is obtained using a deep convolutional neural network. Using the collected data we progressively improve that model. Every time we have an improved version, we can in turn correct and enhance the data

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Laurain, Alexandre. "Sources laser à semiconducteur à émission verticale de haute cohérence et de forte puissance dans le proche et le moyen infrarouge". Phd thesis, Université Montpellier II - Sciences et Techniques du Languedoc, 2010. http://tel.archives-ouvertes.fr/tel-00613743.

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Le développement de sources lasers monomodes et accordables constitue un enjeu important dans plusieurs domaines en fort développement telle que la métrologie, les senseurs optiques, la spectroscopie, le traitement optique de l'information ou la médecine. Dans cette thèse nous faisons le point sur les limites des technologies actuelles, puis nous montrons comment les surpasser à travers la conception et l'étude physique de lasers à semiconducteur de haute cohérence émettant dans l'infrarouge. Nous nous intéressons particulièrement aux VECSEL dans le but d'obtenir un fonctionnement monofréquence accordables et robustes. Nous traitons de la conception et de la caractérisation de ces lasers, depuis l'optimisation du milieu à gain jusqu'à l'élaboration de prototypes laser fonctionnels. Nous effectuons ensuite une étude approfondie des propriétés physiques de la source. Les différents sujets abordés traitent de nombreux aspects de l'optoélectronique tels que la physique du solide, l'optique traditionnelle et quantique, la technologie des matériaux, la thermique, ect. Les travaux présentés ici ouvrent la voie à de nombreux développements liés aux VECSEL et à leurs applications.

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Rame, Jérémy. "Recherche et élaboration de nouveaux matériaux pour les applications laser non-linéaires du moyen infrarouge". Electronic Thesis or Diss., Paris 6, 2014. http://www.theses.fr/2014PA066716.

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Le moyen infrarouge (MIR) présente un fort intérêt technologique du fait de la présence de bandes de transparence de l’atmosphère dans ce domaine. En effet, elles permettent d’envisager de nombreuses applications à longue distance, telles que la détection de gaz ou le brouillage infrarouge de missiles pour la sécurité des aéronefs civils ou militaires. Les sources paramétriques optiques font partie des technologies de choix pour la génération d’impulsions laser dans ce domaine. Elles nécessitent l’emploi de cristaux non-linéaires pour convertir des signaux laser, du proche infrarouge vers le MIR, dont un état de l’art est présenté dans cette étude. AgGaGeS4 est un candidat prometteur pour ces applications. L’élaboration de ce matériau par la technique de synthèse chimique double zone et la cristallogenèse par la technique Bridgman-Stockbarger est ici présentée. Des lingots d’AgGaGeS4 (φ=28 mm et L=70 mm) ont pu être obtenus. Les facteurs clés pour le développement de ces cristaux ont été mis en évidence, en particulier le contrôle de la volatilité du GeS2. Par ailleurs, un dispositif permettant d’améliorer la méthode de synthèse chimique, en mesurant en temps réel les variations de pression au cours du procédé, est proposé. Concernant ZnGeP2, matériau de référence dans ce domaine, des simulations ab initio ont été réalisées pour étudier l’influence de substitutions ioniques sur les propriétés de ce composé. En complément, des monocristaux de ZGP:Sn ont été élaborés et caractérisés. L’ajout d’étain a permis d’améliorer significativement la transmission optique vers 2 μm, longueur d’onde de pompage de ce cristal
Mid-infrared laser sources have attracted a particular attention due to their potential applications in different fields, such as remote chemical sensing or infrared counter-measures for civilian or military aircrafts safety. One way to produce such sources is the down conversion process in optical parametric oscillators using nonlinear crystals. AgGaGeS4 is a promising candidate for these applications. The chemical synthesis and crystal growth steps of this material processing are presented in this study. Ingots with 28 mm diameter and 70 mm length were grown. The key issue of AgGaGeS4 processing is the control of melt decomposition at high temperature due to the high volatility of GeS2. The influence of GeS2 volatility on melt stoichiometry during the AgGaGeS4 processing is outlined, and solutions to improve crystals quality by controlling this volatility are presented. Otherwise, we present the development of a device which aim to improve the chemical synthesis process by controlling the pressure variations during the chemical reaction. Main interests of this device are to study the chemical reaction which occurs during the process and control the pressure variations during the chemical reaction. Furthermore, ab initio calculations were performed in order to study the properties of ZnGeP2 which is a benchmark material for mid-IR laser conversion. The effect of ionic substitution on ZnGeP2 properties was studied. Moreover, ZnGeP2:Sn crystals were elaborated and characterized. It was demonstrated that ionic substitutions with tin allowed significantly improvements on the crystal transmission around the pump wavelength at 2.05 μm

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Dury, Martin. "Development of the NPL wide-area MIR calibration source". Thesis, University of Reading, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555860.

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A portable large area specular-diffuse secondary radiance transfer standard developed for the in-field calibration of remote sensing instrumentation for hot gas emission spectroscopy was designed, produced and characterised to a limited budget. The cavity has an aperture diameter of 102 mm was designed to have a known spectral radiance with a 1 % uncertainty in the 2.5 urn to 14 μm wavelength range. The prototype cavity is based around a grooved base that is electrically heated to temperatures up to 1000 K. The base has been applied with a high emittance coating, which was selected after extensive testing and does not deteriorate after repeated heating. Highly reflective walls surround the emitting base and are water-cooled. '. Coating selection was determined through reflectance measurements of both highly emitting and highly reflective coatings that were performed across the spectral range from 0.3 μm to 14 μm. The reflectance data was subsequently input into black body modelling software and Monte Carlo calculations were performed to optimise the design of the cavity. Problems regarding the heating elements within the emitting base lead to the development of a cost effective solution. Characterisation of the cavity was performed at a wavelength of 800 nm using filter radiometers. Large temperature discrepancies were observed across the cavity aperture and a correction factor was implemented to determine the temperature distribution across the cavity. The temperature distributions were input into black body modelling software and the cavity performance simulated. Radiance measurements of the cavity were performed using an FTIR spectrometer and the cavity emissivity determined to be 0.98 (±0.04) in the wavelength interval from 3.64 to 3.65 μm (the wavenumber interval from 2747 cm-I to 2740 cm").

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Liu, Miaomiao. "Actinomycetes Sourced From Unique Environments as a Promising Source of New TB-Active Natural Products". Thesis, Griffith University, 2017. http://hdl.handle.net/10072/366523.

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Tuberculosis (TB) is the leading cause of death from infectious diseases in the world, affecting more than ten million patients each year. However, multi-drug resistance (MDR-TB) threatens progress achieved in TB care and control, and there are few drugs available to treat MDR-TB. Our overall aim was to identify anti-TB natural products from microbes sourced from unique environments. This thesis presents efforts to achieve an effective approach to identify anti-TB microbial natural products with the combination of one strain many compounds (OSMAC) strategy, NMR fingerprint and principal component analysis. The thesis begins with an introduction of TB and the current anti-TB drugs and candidates. It also covers a review on anti-TB natural products from marine microbe and endophyte origin and analysis of their physicochemical properties using Lipinski’s rule of five as well as the ChemGPS tool. As part of a research program aiming to identify anti-TB microbial constituents, a cell-based screening assay was developed to screen 2562 crude extracts. Among the active hits, 46 actinomyces isolated from marine, desert or Traditional Chinese Medicines were selected for further chemical investigation according to their chemical profiles or anti-TB activities. The results are presented in chapters 2 to 7.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Natural Sciences
Science, Environment, Engineering and Technology
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Mörz, Florian [Verfasser]. "Ultrafast laser sources : tunable, ultrafast laser sources for near- and mid-IR spectroscopy / Florian Mörz". Stuttgart : Universitätsbibliothek der Universität Stuttgart, 2020. http://d-nb.info/1222515504/34.

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Wei, Junxiong. "Novel nonlinear frequency conversion sources in the mid-infrared". Doctoral thesis, Universitat Politècnica de Catalunya, 2018. http://hdl.handle.net/10803/664929.

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The goal of this thesis has been the development of a new class of advanced solid-state photonic sources for the mid-infrared (mid-IR) spectral regions, where there exists a severe shortage of practical coherent laser sources, and many scientific and technological applications can benefit. The strategy has been to exploit nonlinear optical techniques based on difference frequency generation (DFG), parametric generation and oscillation, in the latest class of mid-IR nonlinear materials, in combination with the most advanced lasers pump sources based on fiber laser technology, to realize novel, high-power coherent source with broad tunability in the mid-IR. Accordingly, we demonstrate an angle-tuned MgO:PPLN picosecond OPO, synchronously pumped by a Yb-fiber laser, for the first time to the best of our knowledge. The OPO is tunable from 1413-1900 nm in the signal togerther with idler tunability across 2418-4307 nm providing a total tunability of 2376 nm in the near-to-mid-IR region, simply by angular interrogation of the MgO:PPLN crystal at room temperature. Using a 10% output coupler, we were able to extract up to 2.4 W of signal at 1664 nm together with an idler power of 1.7 W at 2950 nm, corresponding to an overall extraction efficiency of ~45% with good beam pointing stability of better than 30 µrad and 14 µrad for the signal and idler, respectively. These results indicate the potential for rapid and wide tunability of high-power OPOs as compared to the temperature tuned devices. In addition, we have demonstrated a novel device based on a tandem configuration, for an injection-seeded pulsed OPO system. Using a 38-mm-long PPLN crystal, we have produced ~0.94 W of average power with 9.7% slope efficiency at 1677 nm, for a pump power of 10 W at 80 kHz repetition rate. The measured optical bandwidth of signal is less than 20 MHz, and the seeding operation is achieved over signal wavelengths ranging from 1510 to 1677 nm, providing a total seeding range of 167 nm in the near-IR region. From a more general viewpoint, the method shownhere will also work at other wavelength range of OPO as well, opening a new path towards injection-seeding or injection-locking of pulse OPOs with full tuning range and high spectral purity. Finally, we present detailed characterization of optical properties of the recently developed nonlinear material, orientation-patterned gallium phosphide (OP-GaP), by performing DFG experiments in the 2492-2782 nm wavelength range in the mid-IR. Detrimental issues such as thermal effects and residual absorption have been studied and confirmed by performing relevant measurements. Temperature and spectral acceptance bandwidths for DFG in the 40-mm-long OP-GaP crystal have been measured to be 18 ºC and 4 nm, respectively, at 1766 nm. Further, we have measured the damage threshold of the OP-GaP crystal to be 0.8 J/cm2 at 1064 nm, for the first time. The polarization dependence of the input beams on the DFG power has also been systematically investigated. To our knowledge, this is the first report on tunable DFG in OP-GaP, as well as the first nanosecond DFG source based on this new nonlinear material
El objetivo de esta tesis era el desarrollo de una nueva clase de fuentes fotónicas de estado sólido para las regiones espectrales del infrarrojo medio (mid-IR), donde existe una gran escasez de fuentes láser coherentes, que pueden ser utilizadas para muchas aplicaciones científicas y tecnológicas. La estrategia consistió en explotar técnicas de óptica no lineal basadas en la generación de frecuencias diferencia (DFG), la generación paramétrica y la oscilación óptica paramétrica, usando la nuevos materiales no lineales para el mid-IR, en combinación con las fuentes de bombeo láser más avanzadas basadas en la tecnología láser de fibra, para realizar nuevas fuentes coherentes de alta potencia y amplia sintonía en el mid-IR. Esta tesis presenta dispositivos de oscilación óptica paramétrica (OPO) usando novedosos diseños, basados en materiales de quasi-phase-matching (QPM) y utilizando nuevos conceptos para facilitar la accesibilidad a la longitud de onda desde 1 μm en la región cercana al infrarrojo cercano hasta la región del mid-IR. En consecuencia, demostramos un OPO de picosegundo con sintonización por ángulo del cristal MgO:PPLN, bombeando sincrónicamente por un láser de fibra de Yb, por primera vez según nuestro conocimiento. El OPO es sintonizable de 1413-1900 nm en el signal juntamente con la sintonización del idler a través de 2418-4307 nm que proporciona una sintonización total de 2376 nm en la región del infrarojo-cercano y mid-IR, simplemente por la interrogación angular del cristal de MgO:PPLN en temperatura ambiente. Utilizando un acoplador de salida del 10%, pudimos extraer hasta 2,4 W de señal a 1664 nm junto con una potencia de idler de 1,7 W a 2950 nm, lo que corresponde a una eficiencia total de extracción de ~45% con una buena estabilidad de apuntamiento del haz mejor que 30 μrad y 14 μrad para el signal y el idler, respectivamente. Estos resultados indican el potencial para una rápida y amplia sintonización de OPOs de alta potencia en comparación con los dispositivos sintonizados por temperatura. Además, demostramos un novedoso dispositivo basado en una configuración en tándem, para un sistema OPO pulsado con un sistema "injection-seeded". Utilizando un cristal PPLN de 38 mm de longitud, hemos producido ~0,94 W de potencia media con una eficiencia de pendiente del 9,7% a 1677 nm, para una potencia de bombeo de 10 W a una tasa de repetición de 80 kHz. La anchura de banda óptica de la señal medida es inferior a 20 MHz, y la operación de "seeding" se realiza en longitudes de onda de la señal que oscilan entre 1510 y 1677 nm, lo que proporciona una gama total de "seeding" de 167 nm en la región cercana al infrarrojo-cercano. Desde un punto de vista más general, el método mostrado aquí también funcionará en otros rangos de longitud de onda de OPO, abriendo un nuevo camino hacia el "seeding" por inyección o el bloqueo por inyección de OPOs de pulso con rango de sintonía completo y alta pureza espectral. Por último, presentamos una caracterización detallada de las propiedades ópticas del material no lineal recientemente desarrollado, el orientation-patterned gallium phosphide (OP-GaP), mediante la realización de experimentos de DFG en el rango de longitud de onda de 2492-2782 nm en el rango de infrarrojos medio. Se han estudiado y confirmado cuestiones perjudiciales como los efectos térmicos y la absorción residual mediante la realización de las mediciones pertinentes. La temperatura y las anchuras de banda de aceptación espectral para DFG en el cristal OP-GaP de 40 mm de longitud han sido medidas obteniendo 18 ºC y 4 nm, respectivamente, a 1766 nm. Además, por primera vez hemos medido el umbral de daño del cristal OP-GaP siendo de 0,8 J/cm2 a 1064 nm. También se ha investigado sistemáticamente la dependencia de la polarización de los haces de entrada con respecto a la potencia de la DFG. Hasta donde sabemos, este es el primer informe sobre DFG sintonizable en OP-GaP, así como la primera fuente de nanosegundos DFG basada en este nuevo material no lineal.

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Nshii, Chidi Christopher. "Tunable mid-infrared light sources based on intersubband transitions". Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2603/.

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This thesis describes how for the first time, unidirectional operation and coupled ring tuning were realised on a quantum cascade laser material; specifically on a new strain compensated In0.7Ga0.3As/AlAs0.6Sb0.4 grown on InP substrate and operates in pulsed mode in the 3-4 micron hydrocarbon absorption region. Unidirectional ring lasers have the advantages that, in the favoured emission direction, they can have up to double the quantum efficiency of bidirectional lasers and do not suffer from spatial hole burning. In this work, this operation was realised by incorporating an "S"-crossover waveguide into the ring cavity in a manner that it introduces non reciprocal loss and gain in the counter-clockwise (CCW) and clockwise (CW) directions respectively. The measured result showed higher quantum efficiency in the CW. In fact at 1.5 times the threshold current, 90 % of the light was emitted in the favoured CW. On the other hand, the coupled ring quantum cascade laser showed nearly single mode operation, with side mode suppression ratio ~22 dB. Continuous wavelength tuning of about 13 nm was observed from one of these devices, at a tuning rate of approximately 0.4 nm/mA.

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Cook, James Matthew. "Mid-fifteenth-century English mass cycles in continental sources". Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/30778/.

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Fifteenth-century English music had a profound impact on mainland Europe, with several important innovations (e.g. the cyclic cantus firmus Mass) credited as English in origin. However, the turbulent history of the Church in England has left few English sources for this deeply influential repertory. The developing narrative surrounding apparently English technical innovations has therefore often focussed on the recognition of English works in continental manuscripts, with these efforts most recently crystallised in Curtis and Wathey's 'Fifteenth-Century English Liturgical Music: A List of the Surviving Repertory'. The focus of discussion until now has generally been on a dichotomy between English and continental origin. However, as more details emerge of the opportunities for cultural cross-fertilisation, it becomes increasingly clear that this may be a false dichotomy. This thesis re-evaluates the complex issues of provenance and diffusion affecting the mid-fifteenth-century cyclic Mass. By breaking down the polarization between English and continental origins, it offers a new understanding of the provenance and subsequent use of many Mass cycles. Contact between England and the continent was frequent, multifarious and quite possibly reciprocal and, despite strong national trends, there exists a body of work that can best be understood in relation to international cultural exchange. This thesis helps to clarify the provenance of a number of Mass cycles, but also suggests that, for Masses such as the anonymous Thomas cesus and Du cuer je souspier, Le Rouge's So ys emprentid, and even perhaps Bedyngham's Sine nomine, cultural exchange is key to our understanding. This thesis also offers a more detailed overview of the chronology of fifteenth-century English Mass cycles and defines their various structural norms, as well as those Masses which depart from these.

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GOEDERT, THERESE. "Les organismes marins, sources de substances antitumorales". Strasbourg 1, 1994. http://www.theses.fr/1994STR15007.

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Kamkin, A. V. Krestʹi︠a︡nskiĭ mir na Russkom Severe: Materialy po istorii severorusskikh krestʹi︠a︡nskikh soobshchestv XVIII veka : uchebnoe posobie. Vologda: Rusʹ, 1999.

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Kosta, Nikolić, Vesović Milan y Dimitrijević Bojan B. 1968-, eds. Rat i mir đenerala: Izabrani ratni spisi. Beograd: Srpska reč, 1998.

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O, Shmidt S., Zaĭt͡s︡ev A. D, Rossiĭskiĭ gosudarstvennyĭ gumanitarnyĭ universitet. Istoriko-arkhivnyĭ institut. y Penzenskai͡a︡ oblastnai͡a︡ administrat͡s︡ii͡a︡. Departament kulʹtury., eds. Mir istochnikovedenii͡a︡: Sbornik v chestʹ Sigurda Ottovicha Shmidta. Moskva: Rossiĭskiĭ gos. gumanitarnyĭ universitet, Istoriko-arkhivnyĭ in-t, 1994.

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I︠U︡, Arapov D., ed. Imperatorskai︠a︡ Rossii︠a︡ i musulʹmanskiĭ mir: Sbornik stateĭ. Moskva: Natalis, 2006.

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A, Denisova T. Malaĭskiĭ mir v malaĭskikh khronikakh XIII-XIX vekov: (moreplavanie, torgovli︠a︡, shariat). Moskva: Federalʹnoe gosudarstvennoe bi︠u︡dzhetnoe uchrezhdenie nauki Institut vostokovedenii︠a︡ RAN, 2012.

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Warnke, Helmuth. Sonntags gönn ich mir die Alster: Hamburger Schubladengeschichten. Hamburg: VSA-Verlag, 1994.

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Rossiĭskiĭ gosudarstvennyĭ arkhiv sot︠s︡ialʹno-politicheskoĭ istorii, ed. Brestskiĭ mir: Prolog, zakli︠u︡chenie, itogi. Moskva: ROSSPĖN, 2022.

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De armas tomar: Vidas cruzadas por el MIR. Santiago de Chile: Ediciones Universidades Diego Portales, 2016.

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Táctica y acción política: Documentos MIR, 1965-1974. [Chile]: Corporación Plataforma Nexos, 2016.

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P, Zykov V., ed. Voĭna i mir Ivana Likhacheva: Syn krasnoi͡a︡rskoĭ zemli. Krasnoi͡a︡rsk: Krasnoi͡a︡rskoe knizhnoe izd-vo, 2001.

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Demirhan, Yasemin, Fulya Turkoglu, Hakan Altan, Cumali Sabah y Lutfi Ozyuzer. "THz Sources and Detectors Fabricated from High Temperature Superconductors". En Terahertz (THz), Mid Infrared (MIR) and Near Infrared (NIR) Technologies for Protection of Critical Infrastructures Against Explosives and CBRN, 153–64. Dordrecht: Springer Netherlands, 2021. http://dx.doi.org/10.1007/978-94-024-2082-1_12.

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Atwill, David G. y Yurong Y. Atwill. "Early to Mid-Qing". En Sources in Chinese History, 2–27. 2^a ed. Second edition. | New York, NY : Routledge, 2021.: Routledge, 2021. http://dx.doi.org/10.4324/9780429265327-2.

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Azimova, Shakhnoza S. y Anna I. Glushenkova. "Hodgsonia kadam Miq. (Trichosathes kadam Miq.)". En Lipids, Lipophilic Components and Essential Oils from Plant Sources, 312. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_965.

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Atwill, David G. y Yurong Y. Atwill. "Mid-Nineteenth-Century Rebellions and Qing Responses". En Sources in Chinese History, 56–80. 2^a ed. Second edition. | New York, NY : Routledge, 2021.: Routledge, 2021. http://dx.doi.org/10.4324/9780429265327-4.

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Dubietis, Audrius, Vytautas Jukna y Arnaud Couairon. "Supercontinuum in IR–MIR from Narrow Bandgap Bulk Solid-State Materials". En The Supercontinuum Laser Source, 457–77. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-06197-4_12.

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Harrison, R. G. y H. N. Rutt. "Mid Infrared Optically Pumped Molecular Gas Lasers". En Physics of New Laser Sources, 201–16. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4757-6187-0_15.

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Azimova, Shakhnoza S. y Anna I. Glushenkova. "Leucothoe keiskei Miq." En Lipids, Lipophilic Components and Essential Oils from Plant Sources, 337. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_1024.

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Azimova, Shakhnoza S. y Anna I. Glushenkova. "Daphniphyllum macropodum Miq." En Lipids, Lipophilic Components and Essential Oils from Plant Sources, 364. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_1114.

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Azimova, Shakhnoza S. y Anna I. Glushenkova. "Acanthopanax spinosus (L.F.) Miq." En Lipids, Lipophilic Components and Essential Oils from Plant Sources, 30–31. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_126.

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Azimova, Shakhnoza S. y Anna I. Glushenkova. "Hedera rhombea (Miq.) Bean". En Lipids, Lipophilic Components and Essential Oils from Plant Sources, 34. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_139.

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Actas de conferencias sobre el tema "Sources MIR"

La Penna, Irene, Tecla Gabbrielli, Francesco Cappelli, Paolo De Natale, Georg Marschick, Robert Weih y Borislav Hinkov. "Electron to photon noise transfer in mid-infrared lasers". En Mid-Infrared Coherent Sources. Washington, D.C.: Optica Publishing Group, 2024. http://dx.doi.org/10.1364/mics.2024.mw3c.6.

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We investigate the noise transfer from injected electrons to emitted photons in coherent mid-infrared (MIR) sources with the aim of finding the best fitting conditions for detection of squeezed light in the MIR.

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Mouras, Rabah, Aladin Mani, Enrico Bagnoli, Tewfik Soulimane, Christophe Silien y Syed A. Tofail. "Label-free, Chemically Selective Mid-Infrared (MIR) Microscopy for Targeted Therapy". En Mid-Infrared Coherent Sources. Washington, D.C.: OSA, 2018. http://dx.doi.org/10.1364/mics.2018.mt3c.7.

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Keilmann, Fritz. "Near-field Microscopy with MIR Combs". En Mid-Infrared Coherent Sources. Washington, D.C.: OSA, 2016. http://dx.doi.org/10.1364/mics.2016.mm1c.5.

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Golz, T., S. Starosielec, J. H. Buss, P. Merkl, E. Zapolnova, M. Schulz, M. Petev, M. J. Prandolini y R. Riedel. "The ELI-ALPS MIR-HE Laser System - Design and Status". En Mid-Infrared Coherent Sources. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/mics.2022.mth5c.3.

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Chang, KaiHsun, Jhih-Yong Han, Azzedine Boudrioua y L. H. PENG. "MIR Generation from 3D c(2) Nonlinear Photonic Crystals". En Compact EUV & X-ray Light Sources. Washington, D.C.: OSA, 2018. http://dx.doi.org/10.1364/euvxray.2018.jt5a.8.

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Zorin, Ivan, Jakob Kilgus, Markus Brandstetter, Rong Su y Bettina Heise. "Supercontinuum sources for multimodal MIR-OCT imaging". En Imaging Systems and Applications. Washington, D.C.: OSA, 2019. http://dx.doi.org/10.1364/isa.2019.ith2b.7.

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Khamis, Mustafa A., Ruben Sevilla y Karin Ennser. "Design of Highly Coherence MIR Supercontinuum Generation in W-type Index Chalcogenide Fiber". En Compact EUV & X-ray Light Sources. Washington, D.C.: OSA, 2018. http://dx.doi.org/10.1364/euvxray.2018.jt5a.11.

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Furniss, David, Boyu Xiao, Angela B. Seddon, Slawomir Sujecki, Lukasz Sojka, Zhuoqi Tang, Dinuka Jayasuriya et al. "Bright Mid-Infrared (MIR) Photoluminescence Sources and their Application in Imaging and Sensing". En 2020 22nd International Conference on Transparent Optical Networks (ICTON). IEEE, 2020. http://dx.doi.org/10.1109/icton51198.2020.9203544.

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Vavriv, D. M. "Clinotrons as powerful sources of terahertz radiation". En 2009 International Workshop Terahertz and Mid Infrared Radiation: Basic Research and Practical Applications (TERA-MIR). IEEE, 2009. http://dx.doi.org/10.1109/teramir.2009.5379613.

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Khodabakhsh, A., R. Krebbers, K. van Kempen, O. Bang, C. R. Petersen y S. M. Cristescu. "FTS Based on MIR Supercontinuum Sources for Trace Gas Detection". En Optics and Photonics for Sensing the Environment. Washington, D.C.: Optica Publishing Group, 2023. http://dx.doi.org/10.1364/es.2023.etu5e.1.

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Mid-infrared supercontinuum sources can provide a broad spectral bandwidth in the molecular fingerprint region, making them very attractive for multispecies trace gas detection. We demonstrate our recent developments in combining these sources with FTS.

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Informes sobre el tema "Sources MIR"

Fenner, B. y D. Thaler. Multicast Source Discovery Protocol (MSDP) MIB. RFC Editor, octubre de 2006. http://dx.doi.org/10.17487/rfc4624.

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Bosenberg, Walter R. Compact Mid-Infrared Source. Phase 1. Fort Belvoir, VA: Defense Technical Information Center, septiembre de 1995. http://dx.doi.org/10.21236/ada304709.

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Hodgkiss, William S. Mid-Frequency Source Array Engineering Salaries. Fort Belvoir, VA: Defense Technical Information Center, junio de 2003. http://dx.doi.org/10.21236/ada425269.

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Hodgkiss, William S. DURIP - Mid-Frequency Source-Receive Array. Fort Belvoir, VA: Defense Technical Information Center, junio de 2003. http://dx.doi.org/10.21236/ada425272.

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Myers, Lawrence E. High-Power Mid-Infrared Laser Source. Fort Belvoir, VA: Defense Technical Information Center, enero de 2000. http://dx.doi.org/10.21236/ada377806.

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Sterling Backus. DEVELOPMENT OF NEW MID-INFRARED ULTRAFAST LASER SOURCES FOR COMPACT COHERENT X-RAY SOURCES. Office of Scientific and Technical Information (OSTI), mayo de 2012. http://dx.doi.org/10.2172/1039939.

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Williams, Ronald, Gary Duncan y Thomas White. Sources, Measurements, and Effects of Segregated Hot Mix Asphalt Pavement. West Lafayette, IN: Purdue University, 1996. http://dx.doi.org/10.5703/1288284313316.

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McCloghrie, K., F. Baker y E. Decker. IEEE 802.5 Station Source Routing MIB using SMIv2. RFC Editor, diciembre de 1994. http://dx.doi.org/10.17487/rfc1749.

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Hopkinson, C. S. Sources and Fates of Dissolved Organic Matter in the Mid-Atlantic Bight. Office of Scientific and Technical Information (OSTI), agosto de 2000. http://dx.doi.org/10.2172/833837.

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Amare, Mulubrhan y Bedru Balana. Climate change, income sources, crop mix, and input use decisions: Evidence from Nigeria. Washington, DC: International Food Policy Research Institute, 2023. http://dx.doi.org/10.2499/p15738coll2.136717.

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