Literatura académica sobre el tema "SncRNA silencing"
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Artículos de revistas sobre el tema "SncRNA silencing"
Carmi, Ofira, Yosef Gotlieb, Yonat Shemer-Avni y Zvi Bentwich. "The Role of HIV-1-Encoded microRNAs in Viral Replication". Microorganisms 12, n.º 3 (20 de febrero de 2024): 425. http://dx.doi.org/10.3390/microorganisms12030425.
Texto completoAlsaadi, Mohammed, Muhammad Yasir Khan, Mahmood Hassan Dalhat, Salem Bahashwan, Muhammad Uzair Khan, Abdulgader Albar, Hussein Almehdar y Ishtiaq Qadri. "Dysregulation of miRNAs in DLBCL: Causative Factor for Pathogenesis, Diagnosis and Prognosis". Diagnostics 11, n.º 10 (22 de septiembre de 2021): 1739. http://dx.doi.org/10.3390/diagnostics11101739.
Texto completoDi Fazio, Arianna, Margarita Schlackow, Sheng Kai Pong, Adele Alagia y Monika Gullerova. "Dicer dependent tRNA derived small RNAs promote nascent RNA silencing". Nucleic Acids Research 50, n.º 3 (20 de enero de 2022): 1734–52. http://dx.doi.org/10.1093/nar/gkac022.
Texto completoHuang, Songqian, Kazutoshi Yoshitake y Shuichi Asakawa. "A Review of Discovery Profiling of PIWI-Interacting RNAs and Their Diverse Functions in Metazoans". International Journal of Molecular Sciences 22, n.º 20 (16 de octubre de 2021): 11166. http://dx.doi.org/10.3390/ijms222011166.
Texto completoShen, Dong-Fang, Hui-Ping Qi, Wei-Na Zhang y Wen-Xu Sang. "Resveratrol Promotes Autophagy to Improve neuronal Injury in Parkinson’s Disease by Regulating SNHG1/miR-128-3p/SNCA Axis". Brain Sciences 13, n.º 8 (25 de julio de 2023): 1124. http://dx.doi.org/10.3390/brainsci13081124.
Texto completoChowdhury, Anisa y Anto P. Rajkumar. "Systematic review of gene expression studies in people with Lewy body dementia". Acta Neuropsychiatrica 32, n.º 6 (17 de marzo de 2020): 281–92. http://dx.doi.org/10.1017/neu.2020.13.
Texto completoRyskalin, Larisa, Rosangela Ferese, Gabriele Morucci, Francesca Biagioni, Carla L. Busceti, Fabrizio Michetti, Paola Lenzi, Alessandro Frati y Francesco Fornai. "Occurrence of Total and Proteinase K-Resistant Alpha-Synuclein in Glioblastoma Cells Depends on mTOR Activity". Cancers 14, n.º 6 (8 de marzo de 2022): 1382. http://dx.doi.org/10.3390/cancers14061382.
Texto completoSmith, Chase H., Raquel Mejia-Trujillo, Sophie Breton, Brendan J. Pinto, Mark Kirkpatrick y Justin C. Havird. "Mitonuclear sex determination? Empirical evidence from bivalves". Molecular Biology and Evolution, 3 de noviembre de 2023. http://dx.doi.org/10.1093/molbev/msad240.
Texto completoWeigert, Nina, Anna-Lena Schweiger, Jonas Gross, Marie Matthes, Selim Corbacioglu, Gunhild Sommer y Tilman Heise. "Detection of a 7SL RNA-derived small non-coding RNA using Molecular Beacons in vitro and in cells". Biological Chemistry, 28 de agosto de 2023. http://dx.doi.org/10.1515/hsz-2023-0185.
Texto completoHuang, Songqian, Shinya Nishiumi, Md Asaduzzaman, Yida Pan, Guanting Liu, Kazutoshi Yoshitake, Kaoru Maeyama et al. "Exosome-derived small non-coding RNAs reveal immune response upon grafting transplantation in Pinctada fucata (Mollusca)". Open Biology 12, n.º 5 (mayo de 2022). http://dx.doi.org/10.1098/rsob.210317.
Texto completoTesis sobre el tema "SncRNA silencing"
Gospodinova, Dimitrova Dilyana. "Functions of tRNA methyltransferases in the small non-coding RNA pathways and intellectual disability". Electronic Thesis or Diss., Sorbonne université, 2020. http://www.theses.fr/2020SORUS384.
Texto completo2’-O-methylation (Nm) can affect RNAs in multiple ways and Nm-modifying enzymes are highly conserved and their dysfunctions are often linked to the development of cancers and brain diseases. An excellent example is the human FTSJ1 - a tRNA Nm-methyltransferase (Nm-MTase) that is conserved in yeast and is associated with Intellectual Disability (ID) in humans and mice. During my PhD work, I contributed on extending the evolutionary portfolio of this enzyme by demonstrating the molecular function of its predicted Drosophila homologs (Trm7_32 and Trm7_34) by using the cutting edge RiboMethSeq technique and the more classical MALDI-TOF. I also unraveled novel tRNA and even potential mRNA targets of human FTSJ1 in cell lines derived from ID patients’ blood carrying various mutations in FTSJ1. A small RNAseq analysis revealed a deregulation of the miRNAs population in FTSJ1 loss of function mutant cells, while in flies, our genetic sensors showed dysfunctional piRNA and Ago2-dependent miRNA silencing pathways when lacking the FTSJ1 orthologs. Northern blot analysis detected the accumulation of specific tRNA fragments (tRFs) derived from tRNAPhe (a major target of the enzymes). Today, we are considering the biomarker potential of these tRFs and testing their conservation in the ID patients’ cell lines. Finally, we used RiboMethseq to evaluate any changes in the Nm-profiles of the mRNA population in FTSJ1 mutant context, thus, opening new possibilities for biological significance of this enzyme. The results from these studies provide further insights in the molecular pathways that govern FTSJ1-dependent ID pathogenesis