Artículos de revistas sobre el tema "Small inhibitory compounds"
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Alvarez-Gonzalez, Juan Antonio, Robert Maul, Rahul M. Kohli y Patricia J. Gearhart. "Small molecule inhibitors of Activation-Induced Deaminase". Journal of Immunology 200, n.º 1_Supplement (1 de mayo de 2018): 48.18. http://dx.doi.org/10.4049/jimmunol.200.supp.48.18.
Texto completoYan, Hua, Tomoko Chiba Mizutani, Nobuhiko Nomura, Tadakazu Takakura, Yoshihiro Kitamura, Hideka Miura, Masako Nishizawa, Masashi Tatsumi, Naoki Yamamoto y Wataru Sugiura. "A Novel Small Molecular Weight Compound with a Carbazole Structure That Demonstrates Potent Human Immunodeficiency Virus Type-1 Integrase Inhibitory Activity". Antiviral Chemistry and Chemotherapy 16, n.º 6 (diciembre de 2005): 363–73. http://dx.doi.org/10.1177/095632020501600603.
Texto completoAsai, Takashi, Tsutomu Takeuchi, Jeff Diffenderfer y L. David Sibley. "Identification of Small-Molecule Inhibitors of Nucleoside Triphosphate Hydrolase in Toxoplasma gondii". Antimicrobial Agents and Chemotherapy 46, n.º 8 (agosto de 2002): 2393–99. http://dx.doi.org/10.1128/aac.46.8.2393-2399.2002.
Texto completoPatkar, Chinmay G., Martha Larsen, Michael Owston, Janet L. Smith y Richard J. Kuhn. "Identification of Inhibitors of Yellow Fever Virus Replication Using a Replicon-Based High-Throughput Assay". Antimicrobial Agents and Chemotherapy 53, n.º 10 (3 de agosto de 2009): 4103–14. http://dx.doi.org/10.1128/aac.00074-09.
Texto completoHan, Chun, Jiahong Ren, Feng Su, Xiaoqin Hu, Mengyao Li, Zhijun Wang y Lintao Wu. "Hybrids of Quinoline and Anilinopyrimidine: Novel EGFRT790M Inhibitors with Antiproliferative Activity against Non-Small Cell Lung Cancer Cell Lines". Anti-Cancer Agents in Medicinal Chemistry 20, n.º 6 (14 de junio de 2020): 724–33. http://dx.doi.org/10.2174/1871520620666200302113206.
Texto completoAbramić, Marija y Dejan Agić. "Survey of Dipeptidyl Peptidase III Inhibitors: From Small Molecules of Microbial or Synthetic Origin to Aprotinin". Molecules 27, n.º 9 (7 de mayo de 2022): 3006. http://dx.doi.org/10.3390/molecules27093006.
Texto completoNoueiry, Amine O., Paul D. Olivo, Urszula Slomczynska, Yi Zhou, Ben Buscher, Brian Geiss, Michael Engle et al. "Identification of Novel Small-Molecule Inhibitors of West Nile Virus Infection". Journal of Virology 81, n.º 21 (22 de agosto de 2007): 11992–2004. http://dx.doi.org/10.1128/jvi.01358-07.
Texto completoLefas, Georgia y George Chaconas. "High-Throughput Screening Identifies Three Inhibitor Classes of the Telomere Resolvase from the Lyme Disease Spirochete". Antimicrobial Agents and Chemotherapy 53, n.º 10 (13 de julio de 2009): 4441–49. http://dx.doi.org/10.1128/aac.00529-09.
Texto completoErcan-Fang, Nacide, Miriam R. Taylor, Judith L. Treadway, Carolyn B. Levy, Paul E. Genereux, E. Michael Gibbs, Virginia L. Rath, Younggil Kwon, Mary C. Gannon y Frank Q. Nuttall. "Endogenous effectors of human liver glycogen phosphorylase modulate effects of indole-site inhibitors". American Journal of Physiology-Endocrinology and Metabolism 289, n.º 3 (septiembre de 2005): E366—E372. http://dx.doi.org/10.1152/ajpendo.00264.2004.
Texto completoYoo, Jihye, Darong Kim, Jiyoung Park, Young-Kook Kim, Hea-Young Park Choo y Hyun Ae Woo. "Novel Small Molecule Inhibitors Targeting the IL-6/STAT3 Pathway or IL-1β". Molecules 27, n.º 9 (22 de abril de 2022): 2696. http://dx.doi.org/10.3390/molecules27092696.
Texto completoRamesh, Priyanka y Shanthi Veerappapillai. "Designing Novel Compounds for the Treatment and Management of RET-Positive Non-Small Cell Lung Cancer—Fragment Based Drug Design Strategy". Molecules 27, n.º 5 (28 de febrero de 2022): 1590. http://dx.doi.org/10.3390/molecules27051590.
Texto completoGong, Mengdie, Mingyan Tu, Hongxia Sun, Lu Li, Lili Zhu, Honglin Li, Zhenjiang Zhao y Shiliang Li. "Design, Synthesis, and Structure–Activity Relationship Study of Potent MAPK11 Inhibitors". Molecules 27, n.º 1 (29 de diciembre de 2021): 203. http://dx.doi.org/10.3390/molecules27010203.
Texto completoTian, Tao, Guo-Ying Chen, Hao Zhang y Feng-Qing Yang. "Personal Glucose Meter for α-Glucosidase Inhibitor Screening Based on the Hydrolysis of Maltose". Molecules 26, n.º 15 (30 de julio de 2021): 4638. http://dx.doi.org/10.3390/molecules26154638.
Texto completoFlaumenhaft, Robert, Lynn VerPlank, James R. Dilks, Price S. Blair, Albert Mairuhu, Joseph Negri, Jason Burbank et al. "A Chemical Genetic Analysis of Platelet Activation." Blood 114, n.º 22 (20 de noviembre de 2009): 4009. http://dx.doi.org/10.1182/blood.v114.22.4009.4009.
Texto completoChoi, Ryan, Mowei Zhou, Roger Shek, Jesse W. Wilson, Logan Tillery, Justin K. Craig, Indraneel A. Salukhe et al. "High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity". PLOS ONE 16, n.º 4 (22 de abril de 2021): e0250019. http://dx.doi.org/10.1371/journal.pone.0250019.
Texto completoRuseva, Nina, Hristina Sbirkova-Dimitrova, Mariyana Atanasova, Ana Marković, Žaklina Šmelcerović, Andrija Šmelcerović, Adriana Bakalova y Emiliya Cherneva. "Synthesis and DNase I Inhibitory Properties of New Squaramides". Molecules 28, n.º 2 (5 de enero de 2023): 538. http://dx.doi.org/10.3390/molecules28020538.
Texto completoHuang, Yuting, Zhaoxing Li, Yuan Ma, Qianqian Wu, Jianping Kong, Lijuan Zhao, Shunxiang Li y Juan Li. "Screening for Active Compounds of Acorus calamus against SARS-CoV-2 Viral Protease and Mechanism Prediction". Pharmaceuticals 17, n.º 3 (1 de marzo de 2024): 325. http://dx.doi.org/10.3390/ph17030325.
Texto completoSato, Yoshiaki, Ikuo Kashiwakura, Masaru Yamaguchi, Hironori Yoshino, Takeshi Tanaka, Ken Ikeda, Zhengmao Ye, Hirotsugu Komatsu, Takao Matsuzaki y Masato Hosoda. "Discovery of a Novel Small-molecule Interleukin-6 Inhibitor Through Virtual Screening Using Artificial Intelligence". Medicinal Chemistry 18, n.º 6 (julio de 2022): 694–700. http://dx.doi.org/10.2174/1573406418666211116144243.
Texto completoPaiboonrungruang, chorlada. "Abstract 6237: Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 6237. http://dx.doi.org/10.1158/1538-7445.am2023-6237.
Texto completoJiang, Suping, Sean T. Prigge, Lan Wei, Yu-e. Gao, Thomas H. Hudson, Lucia Gerena, John B. Dame y Dennis E. Kyle. "New Class of Small Nonpeptidyl Compounds BlocksPlasmodium falciparum Development In Vitro by Inhibiting Plasmepsins". Antimicrobial Agents and Chemotherapy 45, n.º 9 (1 de septiembre de 2001): 2577–84. http://dx.doi.org/10.1128/aac.45.9.2577-2584.2001.
Texto completoMoi, Davide, Alessandro Deplano, Andrea Angeli, Gianfranco Balboni, Claudiu T. Supuran y Valentina Onnis. "Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity". Molecules 27, n.º 17 (23 de agosto de 2022): 5370. http://dx.doi.org/10.3390/molecules27175370.
Texto completoAl-Sanea, Mohammad M. "Synthesis and biological evaluation of small molecule modulators of CDK8/Cyclin C complex with phenylaminoquinoline scaffold". PeerJ 8 (13 de marzo de 2020): e8649. http://dx.doi.org/10.7717/peerj.8649.
Texto completoGao, Yinghong, Stephen P. Davies, Martin Augustin, Anna Woodward, Umesh A. Patel, Robert Kovelman y Kevin J. Harvey. "A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery". Biochemical Journal 451, n.º 2 (28 de marzo de 2013): 313–28. http://dx.doi.org/10.1042/bj20121418.
Texto completoCruz-Migoni, Abimael, Peter Canning, Camilo E. Quevedo, Carole J. R. Bataille, Nicolas Bery, Ami Miller, Angela J. Russell, Simon E. V. Phillips, Stephen B. Carr y Terence H. Rabbitts. "Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds". Proceedings of the National Academy of Sciences 116, n.º 7 (25 de enero de 2019): 2545–50. http://dx.doi.org/10.1073/pnas.1811360116.
Texto completoRamshini, Hassan, Reza Tayebee, Alessandra Bigi, Francesco Bemporad, Cristina Cecchi y Fabrizio Chiti. "Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation". International Journal of Molecular Sciences 20, n.º 22 (7 de noviembre de 2019): 5558. http://dx.doi.org/10.3390/ijms20225558.
Texto completoMinhas, Richa y Yogita Bansal. "iNOS inhibitors: Benzimidazole-coumarin derivatives to combat inflammation". European Journal of Chemistry 13, n.º 3 (30 de septiembre de 2022): 307–18. http://dx.doi.org/10.5155/eurjchem.13.3.307-318.2282.
Texto completoChattopadhyay, Shrikanta, Alison L. Stewart, Siddhartha Mukherjee, Cherrie Huang, Kimberly A. Hartwell, Peter G. Miller, Leigh Carmody et al. "Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma". Blood 120, n.º 21 (16 de noviembre de 2012): 571. http://dx.doi.org/10.1182/blood.v120.21.571.571.
Texto completoAdachi, Ryutaro, Tsuyoshi Ishii, Shinichi Matsumoto, Takuya Satou, Junichi Sakamoto y Tomohiro Kawamoto. "Discovery of Human Intestinal MGAT Inhibitors Using High-Throughput Mass Spectrometry". SLAS DISCOVERY: Advancing the Science of Drug Discovery 22, n.º 4 (8 de octubre de 2016): 360–65. http://dx.doi.org/10.1177/1087057116673181.
Texto completoMavridis, Evangelos, Eleftherios Bermperoglou, Eleni Pontiki y Dimitra Hadjipavlou-Litina. "5-(4H)-Oxazolones and Their Benzamides as Potential Bioactive Small Molecules". Molecules 25, n.º 14 (11 de julio de 2020): 3173. http://dx.doi.org/10.3390/molecules25143173.
Texto completoTrenholme, Katharine, Linda Marek, Sandra Duffy, Gabriele Pradel, Gillian Fisher, Finn K. Hansen, Tina S. Skinner-Adams et al. "Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules". Antimicrobial Agents and Chemotherapy 58, n.º 7 (14 de abril de 2014): 3666–78. http://dx.doi.org/10.1128/aac.02721-13.
Texto completoZhao, Hongchuan, Pu Sun, Wei Guo, Yi Wang, Ao Zhang, Linghua Meng y Chunyong Ding. "Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO-1) Inhibitors Based on Ortho-Naphthaquinone-Containing Natural Product". Molecules 24, n.º 6 (18 de marzo de 2019): 1059. http://dx.doi.org/10.3390/molecules24061059.
Texto completoFurbish, Amelia B., Ahmed S. Alford, Pieter Burger, Yuri K. Peterson, Tracy Murray-Stewart, Robert A. Casero y Patrick M. Woster. "Identification and Characterization of Novel Small-Molecule SMOX Inhibitors". Medical Sciences 10, n.º 3 (30 de agosto de 2022): 47. http://dx.doi.org/10.3390/medsci10030047.
Texto completoVENÄLÄINEN, Jarkko I., Risto O. JUVONEN, J. Arturo GARCIA-HORSMAN, Erik A. A. WALLÉN, Johannes A. M. CHRISTIAANS, Elina M. JARHO, Jukka GYNTHER y Pekka T. MÄNNISTÖ. "Slow-binding inhibitors of prolyl oligopeptidase with different functional groups at the P1 site". Biochemical Journal 382, n.º 3 (7 de septiembre de 2004): 1003–8. http://dx.doi.org/10.1042/bj20040992.
Texto completoKollár, Levente, Martina Gobec, Matic Proj, Lara Smrdel, Damijan Knez, Tímea Imre, Ágnes Gömöry et al. "Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads". Cells 10, n.º 12 (6 de diciembre de 2021): 3431. http://dx.doi.org/10.3390/cells10123431.
Texto completoNordio, Giulia, Francesco Piazzola, Giorgio Cozza, Monica Rossetto, Manuela Cervelli, Anna Minarini, Filippo Basagni et al. "From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs". Molecules 28, n.º 17 (29 de agosto de 2023): 6329. http://dx.doi.org/10.3390/molecules28176329.
Texto completoMoon, Sungho, Seon Yeon Cho, Minhye Kim, Soojeong Beak, Jinhyuk Kim, Yongchan Kim, Sungil Park et al. "Abstract B142: Discovery of novel and potent TEAD inhibitors, orally available small molecules with anti-tumor activity in hippo pathway- dysregulated cancers". Molecular Cancer Therapeutics 22, n.º 12_Supplement (1 de diciembre de 2023): B142. http://dx.doi.org/10.1158/1535-7163.targ-23-b142.
Texto completoRusina, Polina, Erik Gandalipov, Yana Abdusheva, Maria Panova, Alexandra Burdenkova, Vasiliy Chaliy, Maria Brachs et al. "Imidazole-4-N-acetamide Derivatives as a Novel Scaffold for Selective Targeting of Cyclin Dependent Kinases". Cancers 15, n.º 15 (25 de julio de 2023): 3766. http://dx.doi.org/10.3390/cancers15153766.
Texto completoFrancini, Cinzia, Francesca Musumeci, Anna Fallacara, Lorenzo Botta, Alessio Molinari, Roberto Artusi, Laura Mennuni, Adriano Angelucci y Silvia Schenone. "Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors". Molecules 23, n.º 9 (17 de septiembre de 2018): 2369. http://dx.doi.org/10.3390/molecules23092369.
Texto completoKulkarni, Amol A., Ayyiliath M. Sajith, Changwen Zhang, Jiukuan Hao y J. Phillip Bowen. "Small molecule prevents inflammation in microglia by targeting the NLRP3 inflammasome". Journal of Immunology 204, n.º 1_Supplement (1 de mayo de 2020): 160.15. http://dx.doi.org/10.4049/jimmunol.204.supp.160.15.
Texto completoRampogu, Shailima, Ayoung Baek, Chanin Park, Shraddha Parate, Saravanan Parameswaran, Yohan Park, Baji Shaik, Ju Hyun Kim, Seok Ju Park y Keun Woo Lee. "Discovery of Small Molecules that Target Vascular Endothelial Growth Factor Receptor-2 Signalling Pathway Employing Molecular Modelling Studies". Cells 8, n.º 3 (21 de marzo de 2019): 269. http://dx.doi.org/10.3390/cells8030269.
Texto completoGising, Johan, Saman Honarnejad, Maaike Bras, Gemma L. Baillie, Stuart P. McElroy, Philip S. Jones, Angus Morrison, Julia Beveridge, Mathias Hallberg y Mats Larhed. "The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds". International Journal of Molecular Sciences 25, n.º 7 (6 de abril de 2024): 4084. http://dx.doi.org/10.3390/ijms25074084.
Texto completoCurreli, Francesca, Shahad Ahmed, Sofia M. B. Victor, Aleksandra Drelich, Siva S. Panda, Andrea Altieri, Alexander V. Kurkin, Chien-Te K. Tseng, Christopher D. Hillyer y Asim K. Debnath. "Discovery of Highly Potent Fusion Inhibitors with Potential Pan-Coronavirus Activity That Effectively Inhibit Major COVID-19 Variants of Concern (VOCs) in Pseudovirus-Based Assays". Viruses 14, n.º 1 (31 de diciembre de 2021): 69. http://dx.doi.org/10.3390/v14010069.
Texto completoElsawi, Ahmed E., Mai I. Shahin, Hager A. Elbendary, Tarfah Al-Warhi, Fatma E. Hassan y Wagdy M. Eldehna. "1,2,4-Triazole-Tethered Indolinones as New Cancer-Fighting Small Molecules Targeting VEGFR-2: Synthesis, Biological Evaluations and Molecular Docking". Pharmaceuticals 17, n.º 1 (8 de enero de 2024): 81. http://dx.doi.org/10.3390/ph17010081.
Texto completoPorubin, Diana. "Inhibition of in Vitro Nitrosation of Nornicotine". Chemistry Journal of Moldova 2, n.º 1 (diciembre de 2007): 78–82. http://dx.doi.org/10.19261/cjm.2007.02(1).11.
Texto completoMontanari, Floriane, Anna Cseke, Katrin Wlcek y Gerhard F. Ecker. "Virtual Screening of DrugBank Reveals Two Drugs as New BCRP Inhibitors". SLAS DISCOVERY: Advancing the Science of Drug Discovery 22, n.º 1 (11 de julio de 2016): 86–93. http://dx.doi.org/10.1177/1087057116657513.
Texto completoZhang, Hao, Feng-Qing Yang y Jian-Li Gao. "A Simple and Portable Personal Glucose Meter Method Combined with Molecular Docking for Screening of Lipase Inhibitors". Evidence-Based Complementary and Alternative Medicine 2022 (22 de septiembre de 2022): 1–9. http://dx.doi.org/10.1155/2022/4430050.
Texto completoAlkhashrom, Sewar, Jintawee Kicuntod, Sigrun Häge, Johannes Schweininger, Yves A. Muller, Peter Lischka, Manfred Marschall y Jutta Eichler. "Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors". Viruses 13, n.º 3 (12 de marzo de 2021): 471. http://dx.doi.org/10.3390/v13030471.
Texto completoYang, Cheng-Wei, Yung-Ning Yang, Po-Huang Liang, Chi-Min Chen, Wei-Liang Chen, Hwan-You Chang, Yu-Sheng Chao y Shiow-Ju Lee. "Novel Small-Molecule Inhibitors of Transmissible Gastroenteritis Virus". Antimicrobial Agents and Chemotherapy 51, n.º 11 (20 de agosto de 2007): 3924–31. http://dx.doi.org/10.1128/aac.00408-07.
Texto completoLiargkova, Thalia, Nikolaos Eleftheriadis, Frank Dekker, Efstathia Voulgari, Constantinos Avgoustakis, Marina Sagnou, Barbara Mavroidi, Maria Pelecanou y Dimitra Hadjipavlou-Litina. "Small Multitarget Molecules Incorporating the Enone Moiety". Molecules 24, n.º 1 (7 de enero de 2019): 199. http://dx.doi.org/10.3390/molecules24010199.
Texto completoZhang, Yan y Niefang Yu. "Design, Synthesis and Biological Evaluation: 5-amino-1H-pyrazole-1- carbonyl derivatives as FGFR Inhibitors". Letters in Drug Design & Discovery 17, n.º 11 (23 de octubre de 2020): 1330–41. http://dx.doi.org/10.2174/1570180817999200608140628.
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