Literatura académica sobre el tema "Sephin1"
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Artículos de revistas sobre el tema "Sephin1"
Ruiz, Asier, Jone Zuazo, Carolina Ortiz-Sanz, Celia Luchena, Carlos Matute y Elena Alberdi. "Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response". International Journal of Molecular Sciences 21, n.º 17 (24 de agosto de 2020): 6088. http://dx.doi.org/10.3390/ijms21176088.
Texto completoCrespillo-Casado, Ana, Zander Claes, Meng S. Choy, Wolfgang Peti, Mathieu Bollen y David Ron. "A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α". Journal of Biological Chemistry 293, n.º 20 (4 de abril de 2018): 7766–76. http://dx.doi.org/10.1074/jbc.ra118.002325.
Texto completoThapa, Simrika, Dalia H. Abdelaziz, Basant A. Abdulrahman y Hermann M. Schatzl. "Sephin1 Reduces Prion Infection in Prion-Infected Cells and Animal Model". Molecular Neurobiology 57, n.º 5 (24 de enero de 2020): 2206–19. http://dx.doi.org/10.1007/s12035-020-01880-y.
Texto completoChen, Yanan, Joseph R. Podojil, Rejani B. Kunjamma, Joshua Jones, Molly Weiner, Wensheng Lin, Stephen D. Miller y Brian Popko. "Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis". Brain 142, n.º 2 (17 de enero de 2019): 344–61. http://dx.doi.org/10.1093/brain/awy322.
Texto completoCallejo, Gerard, Luke A. Pattison, Jack C. Greenhalgh, Sampurna Chakrabarti, Evangelia Andreopoulou, James R. F. Hockley, Ewan St John Smith y Taufiq Rahman. "In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3". Biochemical Pharmacology 174 (abril de 2020): 113834. http://dx.doi.org/10.1016/j.bcp.2020.113834.
Texto completoMaltsev, Alexander V., Anna B. Nikiforova, Natalia V. Bal y Pavel M. Balaban. "Amyloid Aβ25-35 Aggregates Say ‘NO’ to Long-Term Potentiation in the Hippocampus through Activation of Stress-Induced Phosphatase 1 and Mitochondrial Na+/Ca2+ Exchanger". International Journal of Molecular Sciences 23, n.º 19 (6 de octubre de 2022): 11848. http://dx.doi.org/10.3390/ijms231911848.
Texto completoBRAILOVSKY, HARRY y ERNESTO BARRERA. "Illustrated key to the species in the genus Sephina (Hemiptera: Heteroptera: Coreidae: Coreinae: Spartocerini), with descriptions of three new species and new distributional records". Zootaxa 5048, n.º 1 (5 de octubre de 2021): 77–98. http://dx.doi.org/10.11646/zootaxa.5048.1.4.
Texto completoJung, Jisu, Yoomin Kim, Jiwoon Na, Lu Qiao, Jeyoung Bang, Dongin Kwon, Tack-Jin Yoo et al. "Constitutive Oxidative Stress by SEPHS1 Deficiency Induces Endothelial Cell Dysfunction". International Journal of Molecular Sciences 22, n.º 21 (28 de octubre de 2021): 11646. http://dx.doi.org/10.3390/ijms222111646.
Texto completoBang, Jeyoung, Minguk Han, Tack-Jin Yoo, Lu Qiao, Jisu Jung, Jiwoon Na, Bradley A. Carlson et al. "Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in Sephs1−/− Mice". International Journal of Molecular Sciences 22, n.º 21 (28 de octubre de 2021): 11647. http://dx.doi.org/10.3390/ijms222111647.
Texto completoVarol, Marie-Christine Bornes. "Haïm Vidal Sephiha (1923 – 2019)". Tsafon, n.º 79 (1 de julio de 2020): 181–83. http://dx.doi.org/10.4000/tsafon.2993.
Texto completoTesis sobre el tema "Sephin1"
Frapporti, Giulia. "Lysosome orchestrates autophagy and integrated stress response: new insights from Sephin1". Doctoral thesis, Università degli studi di Trento, 2023. https://hdl.handle.net/11572/363904.
Texto completoDi, Lalla Matthew. "Validation of synthetic lethal hits of microtubule targeting agents". Thesis, 2020. http://hdl.handle.net/1866/25171.
Texto completoMicrotubules, key components of the eukaryotic cytoskeleton, are highly dynamic polymers of tubulin implicated in a wide variety of cellular processes. Their essential roles in the cell cycle have made them a valid target in cancer therapy. Despite the clinical efficacy of microtubule targeting agents (MTA), their use is hampered by side effects. We sought to identify genetic vulnerabilities that can be exploited to decrease the required dose while maintaining efficacy, and therefore reduce side effects. In collaboration with the Tyers laboratory at IRIC, we carried out a genetic screen based on synthetic lethality with antiproliferative agents, including MTAs. We have selected genes whose knockout sensitized cells to MTAs. I have confirmed that the knockout of GNA13, SEPHS1, DLGAP5, and QRICH1, DLGAP5, sensitize NALM6 cells to docetaxel and vincristine respectively. However, no knockout of these genes increased the sensitivity to docetaxel in U2OS cells. In addition to its effect with docetaxel, GNA13 stood out as being a particularly exciting target. GNA13 knockout increased the frequency and severity of chromosome segregation errors in U2OS cells. This increase was not corrected following treatment with UMK57, a molecule known to reduce the rate of chromosome segregation errors. Interestingly, the GNA13 knockout also increased the frequency of chromosome segregation errors in non-cancerous and chromosomally stable RPE1 cells. This suggests that GNA13 does not require transformation nor chromosomal instability as prerequisites for exacerbating chromosomal instability. Overall, these results open up a new avenue of anticancer therapeutic strategies, namely, the treatment of cancers presenting mutations in QRICH1, DLGAP5, GNA13, and SEPHS1 with lower doses of MTAs. In particular, GNA13 is frequently mutated in certain lymphomas. In addition, the results obtained demonstrate that GNA13 knockout exacerbates chromosomal instability and, therefore, could be involved in carcinogenesis.
Oudouhou, Flore. "Analyse biochimique et inhibition de complexes macromoléculaires dans des cellules humaines et bactériennes". Thèse, 2018. http://hdl.handle.net/1866/21802.
Texto completoLibros sobre el tema "Sephin1"
Lorato lwa sephiri: Tswana drama. Midrand: Educum Publishers, 1994.
Buscar texto completoBlade, Adam. Sephir, the storm monster. Sydney: Orchard Books, 2009.
Buscar texto completoHamilton, Joe L. Kia Sephia & Spectra automotive repair manual. Sparkford, Nr Yeovil, Somerset: Haynes Pub. Group, 2010.
Buscar texto completoHamilton, Joe L. Kia Sephia & Spectra automotive repair manual. Somerset, England: Haynes Pub. Group, 2005.
Buscar texto completoHamilton, Joe L. Chilton's Kia Sephia & Spectra 1994-04 repair manual. Newbury Park, Calif: Haynes North America, 2005.
Buscar texto completoHamilton, Joe L. Chilton's Kia Sephia & Spectra 1994-04 repair manual. Newbury Park, Calif: Haynes North America, 2005.
Buscar texto completoMakean, John. Sephira. Lulu.com, 2006.
Buscar texto completoVari, Autori Autori, Danilo Simoni, Nathan Blade y Silvia Licetti. Sephir. Independently Published, 2017.
Buscar texto completoSephiri (Children's Stories). Juta Gariep, 2004.
Buscar texto completoal, et, R. Schermbrucker y R. Viljoen. Sephiri (Children's Stories). Juta Gariep, 2004.
Buscar texto completoCapítulos de libros sobre el tema "Sephin1"
ALEKSANDER, N. "Sephira". En Digital Art Masters, 126–31. Elsevier, 2009. http://dx.doi.org/10.1016/b978-0-240-52170-1.50024-2.
Texto completoActas de conferencias sobre el tema "Sephin1"
Almeida, Jamile Aislin Silva de y Carla Yasmym De Carvalho Lima. "NUTRIGENÔMICA E AS DOENÇAS CRÔNICAS NÃO TRANSMISSÍVEIS: UMA REVISÃO BIBLIOGRÁFICA ENTRE OS POLIFORMISMOS E COMPOSTOS BIOATIVOS". En II Congresso Brasileiro de Biologia Molecular On-line. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/2323.
Texto completoInformes sobre el tema "Sephin1"
Kyser, E. A. Validation of the SEPHIS Program for the Modeling of the HM Process. Office of Scientific and Technical Information (OSTI), diciembre de 1998. http://dx.doi.org/10.2172/4836.
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