Tesis sobre el tema "Roles"
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Malone, Laurell Coleman M. S. "The Multiple Roles of Women Pursuing Doctoral Studies". Diss., Virginia Tech, 1998. http://hdl.handle.net/10919/30544.
Texto completoEd. D.
Sundström, Rasmus. "Upplevelsen av att dela hem och arbete med samma person". Thesis, Mälardalen University, Department of Social Sciences, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-402.
Texto completoSyftet med denna studie var att undersöka hur multipla roller upplevs och hanteras av personer som delar en professionell och en privat domän. Tidigare forskning har visat att multipla roller ofta upplevs som stressande och är en grund till konflikter i såväl den privata som den professionella domänen. Åtta personer i fyra intervjupar intervjuades individuellt med hjälp av en semistrukturerad intervjuguide. Studiens resultat visar att samtliga deltagare har positiva upplevelser kring de delade domänerna då de anses ge en ökad förståelse för den andra parten och leda till en utvecklad relation. Vidare forskning föreslås koncentreras kring negativa upplevelser av fenomenet då denna undersökning inte undersökt detta.
Wilkey, Brian Mize. "Gender Role Flexibility: An Account of Its Effects on Career Role Projections". Miami University Honors Theses / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=muhonors1272047704.
Texto completoSimonsen, Gregory. "Masculine Role Conflict in Gay Men: Mediation of Psychological Well-Being and Help-Seeking Behaviors". Thesis, University of North Texas, 1998. https://digital.library.unt.edu/ark:/67531/metadc278913/.
Texto completoLeuthäuser, Max. "A Pure Embedding of Roles". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-227624.
Texto completoAl, Shirawi Thaira Mohammed. "Strategy implementation : exploring roles, perceptions, and expectations of middle managers' practices". Thesis, Brunel University, 2015. http://bura.brunel.ac.uk/handle/2438/12817.
Texto completoRahimi, Rastgar Sanaz y Niloufar Razavi. "A System for Building Corpus Annotated With Semantic Roles". Thesis, Tekniska Högskolan, Högskolan i Jönköping, JTH. Forskningsmiljö Informationsteknik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-20594.
Texto completoLang, Joel. "Unsupervised induction of semantic roles". Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/6254.
Texto completoReiss, Richard Arnold. "Three Roles". Kent State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=kent1237405268.
Texto completoThomason, Lisa Aaron. "Role Strain Among Lesbian, Gay, Bisexual, Transgender, Queer Couples Diagnosed with Cancer". ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5664.
Texto completoBoxwell, Stephen Arthur. "A CCG-Based Method for Training a Semantic Role Labeler in the Absence of Explicit Syntactic Training Data". The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1322594816.
Texto completoKruger, Karen. "Experiences of gender role assignment by women in transitional marriages". University of the Western Cape, 2015. http://hdl.handle.net/11394/5103.
Texto completoBACKGROUND: Global female workforce participation has increased rapidly over the past few decades, and the majority of marriages are now dual-earning. Marriages were therefore expected to shift from traditional to egalitarian, where household tasks are shared equally between spouses. However, decades later, the majority of marriages are still found to be in a transitional phase, where women are employed outside of the home, but maintain responsibility for the majority of domestic tasks and childcare. The transitional marriage holds a number of complications for spouses, as gender roles are no longer clearly defined and more difficult to negotiate. Married women are under particular strain as they now have to balance both the work and family roles. OBJECT: The aim of the present study is to gain a better understanding of how women in transitional marriages experience and make meaning of the roles that they fulfil. Minimal research has been devoted to this issue, and the literature largely focuses on marriages at the traditional or egalitarian ends of the gender role spectrum. METHOD: Semi-structured interviews were conducted with eight women in transitional marriages, with children living at home. The data were examined using thematic analysis. RESULTS: The results indicated that the majority of participants worked out of economic necessity as opposed to choice, and that half of the participants earned more than their spouses. Most participants still harboured traditional gender beliefs even though their external circumstances had changed. This discrepancy seemed to cause significant internal and marital conflict, yet the attainment of more egalitarian beliefs seemed difficult to attain owing to feelings of guilt and a perceived threat of identity loss. Consequently, the majority of participants had difficulty relinquishing control over several household tasks. Furthermore, demanding work hours, the lack of family-friendly policies at work, and cultural factors also played a role in the maintenance of traditional beliefs by participants CONCLUSIONS: Much research still needs to be conducted to gain a more thorough understanding of changing gender roles in society, as well as to inform new workforce legislation that could enhance the lives of families. Lastly, as most studies focus on the experiences of women regarding the division of labour (probably because of the significant adaptations that have occurred in women’s roles), it becomes necessary to gain an understanding of the experiences of men as well, particularly if research is going to be utilised for the benefit of the whole family. As became evident, unequal division of tasks is often maintained by women for several reasons, and is no longer necessarily the result of oppression by men, as much of the literature suggests.
Bloomfield, Elizabeth A. "Gender role stereotyping and art interpretation". Thesis, University of Iowa, 2015. https://ir.uiowa.edu/etd/1550.
Texto completoLanter, Jason Richard. "“Not that there’s anything wrong with that…”: Perceptions of Masculine Men and Feminine Men as a Breadwinner or Caregiver". Miami University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=miami1218060049.
Texto completoLommers-Johnson, Tess A. "Stressful Scriptures: Gender Role Ideology, Gender Role Stress, and Christian Religiosity". Scholarship @ Claremont, 2016. http://scholarship.claremont.edu/scripps_theses/761.
Texto completoWebb, Gary Ray. "An Examination of Gender Role Differentiation in Crowd and Collective Behavior". Thesis, University of North Texas, 1994. https://digital.library.unt.edu/ark:/67531/metadc278003/.
Texto completoGadd, Karen Jane. "Role theory revisited : a frame analysis of occupational health roles". Thesis, University of Portsmouth, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306950.
Texto completoAndersson, Julia y Rebecka From. ""Om jag jobbar jag förstår vem jag är och jag är stark" : En fallstudie om somaliskfödda kvinnors upplevelser av förvärvsarbetets effekter på deras vardagsliv och familjeroller i Sverige". Thesis, Högskolan för lärande och kommunikation, Högskolan i Jönköping, HLK, Globala studier, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-36095.
Texto completoSomali-born immigrants are often described as the most difficult group to integrate into Swedish society with an extensive underrepresentation on the Swedish labour market as well as traditional values and gender roles that often dictate the division of labour and functions in the family. This study aims to examine the effects of a job on Somali family roles from a migration perspective. By comparing wage-earning and unemployed Somali-born women's experiences, the study also aspires to elucidate the importance of a job in their everyday life. The essay is based on previous research on the historical, social and transnational dimensions of Somali family life and culture, as well as theoretical concepts such as role conflict, role change and role negotiation. A qualitative comparative case study has been conducted, based on data from semi-structured interviews. Eight respondents participated in the survey – four employed and four unemployed women born in Somalia. The results were then analyzed in the light of previous research and the theoretical concepts. The result shows that there are some interesting differences between the two groups. The Somali families in which the women are unemployed have a distinct division of the household work, where the woman assumes the majority of the workload. Here it is also clear that traditional Somali family roles are still of importance. However, in the families where the Somali-born women have employment, traditional family roles have changed and led to a more even distribution of household work, where the men, women and children share the responsibility. Furthermore, it appears that the unemployed Somali-born women are very keen to have a job, as independence from the state and government is a main driving force. For the wage-earners on the other hand, there is a clearer focus on being independent from the man and being able to be a decision-maker in family matters. The result also illustrates how society's expectations on women influence their driving forces to work and the way they think about their role in the family.
Wupperman, Peggilee. "Differences in Depressive Symptoms as a Function of Gender, Roles, and Rumination". Thesis, University of North Texas, 2003. https://digital.library.unt.edu/ark:/67531/metadc4375/.
Texto completoHackworth, Franchesca R. "The Role of Journalists During the COVID-19 Pandemic: The Relationship Between Journalism Roles and Media Trust". University of Dayton / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1619618453512626.
Texto completoLangley, Dorothy Margaret. "Dramatherapy and psychodrama : towards a relationship". Thesis, University of Exeter, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288363.
Texto completoSundkvist, Magdalena. "Love' s function in marital decisions : Materialist feminism in Jane Austen's Emma, Pride and Prejudice and Northanger Abbey". Thesis, Umeå universitet, Institutionen för språkstudier, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-121968.
Texto completoErickson, Darrin Jerroll. "Relinquishing Canada's nuclear roles". Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29675.
Texto completoArts, Faculty of
Political Science, Department of
Graduate
Torbett, Neil Edward. "Cellular roles of PKN1". Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406323.
Texto completoJöneros, Jenny y Hugo Tinglöf. "Social roles in gaming". Thesis, Malmö högskola, Fakulteten för teknik och samhälle (TS), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-20833.
Texto completoThis paper explores communication and group dynamics in digital gaming. The purpose of doing this is to establish if there is a correlation between these and the player´s ultimate experience. Past research has shown that communication has a direct influence on the player´s performance, while in a group setting. There is relatively limited amounts of research into group dynamics and how it relates to communication and performance in games. However there is a vast amount of research that relates to roles within a multiplayer setting. Therefor experiments were performed to observe various roles and what impact they had upon the dynamic of the each group. Each group consisted of four candidates that were asked to play a game. During play they were observed and recorded for further analysis in regards to their performance, communication and ultimately what roles they all filled. We saw a connection between communication and group-dynamics and how it affected the player’s performance. Furthermore, we have presented the different roles that appeared and what they want from a game.
Lovings, Erin. "The role of media in teacher's leadership roles and teaching practices". Diss., Connect to online resource, 2005. http://wwwlib.umi.com/cr/colorado/fullcit?p1425753.
Texto completoLoo, Kevin. "OCBs Gone Bad: The Moderating Roles of Burnout and Role Overload". Scholar Commons, 2010. http://scholarcommons.usf.edu/etd/3636.
Texto completoGil, Vallejo Lara. "Exploiting verb similarity for event modelling". Doctoral thesis, Universitat Oberta de Catalunya, 2020. http://hdl.handle.net/10803/668907.
Texto completoEste trabajo se enmarca dentro del ámbito del procesamiento del lenguaje natural. Su objetivo es explorar el potencial de la similitud verbal y, más concretamente, de las clasificaciones verbales, a la hora de capturar y modelizar la información básica relacionada con la expresión de acontecimientos en español. La tesis se articula en torno a dos estudios que examinan la capacidad de la similitud verbal para modelizar la información relativa a los participantes en acontecimientos. En primer lugar, elaboramos un análisis de la similitud verbal con relación a la estructura argumental. Para ello tomamos tres perspectivas que tratan este tema: la lingüística teórica, lingüística de corpus y la psicolingüística, y analizamos de qué modo cada una de ellas define la similitud entre los verbos. Este análisis nos sirve para definir un conjunto de características lingüísticas y configuraciones que se aplican en el segundo estudio. Este estudio consiste en la creación de una clasificación automática de sentidos verbales usando un algoritmo de agrupamiento (clustering). El objetivo de esta clasificación es capturar la estructura argumental de los verbos y reflejarla en las clases, de tal manera que permita modelizar a los participantes en los acontecimientos expresados por los verbos. Los hallazgos nos permiten afirmar que la clasificación verbal organiza la información de manera que es capaz de acomodar diferentes aspectos de la estructura argumental.
This paper aims to explore the potential of verb similarity, and more specifically of verb classifications, when it comes to capturing and modelling basic information related to events expressed in Spanish. The research is based on two studies that examine verb similarity's ability to model event participant information. We first perform a study of verb similarity with respect to argument structure, looking at its relevant characteristics through the lens of three different perspectives: linguistic theory, corpus linguistics and psycholinguistics. Based on this analysis, we choose the features and configurations to be explored in order to create an automatic classification of verb senses using a clustering algorithm. The aim of this automatic classification is to capture the argument structure of the verbs and apply it to the classifications in a way that allows us to adequately model the participants in the events expressed by those verbs. The evaluations carried out for this verb classification confirm automatic classifications' ability to capture and infer relevant information related to participants in events.
Raisor, Jodi Renee. "Doctor of Nursing Practice Roles in Academia". ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7063.
Texto completoGershenoff, Amy Beth. "Leadership Emergence and Gender Roles: A Contextual Examination". Thesis, Virginia Tech, 1999. http://hdl.handle.net/10919/42663.
Texto completoMaster of Science
Neill, Marlene S. "The role of public relations education in preparing students for managerial roles". Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/4916.
Texto completoThe entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on April 2, 2008) Includes bibliographical references.
Motori, Elisa <1983>. "Neuroinflammation and the role of glia: relevance for neurodegenerative and neurosupportive roles". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4769/.
Texto completoÈ ormai assodato che la neuro infiammazione costituisce una caratteristica comune a numerose patologie neurodegenerative. Tra le cellule gliali che mediano la risposta infiammatoria nel sistema nervoso centrale, gli astrociti rivestono un ruolo particolarmente importante in quanto, oltre a rispondere allo stimolo di molecole pro-infiammatorie esogene o prodotte dalla stessa microglia attivata, producono anche fattori di crescita e neurotrofine essenziali per la sopravvivenza della cellula neuronale. Tuttavia, i meccanismi subcellulari che mediano la prima risposta degli astrociti a stimoli pro-infiammatori non sono ben noti. I nostri dati suggeriscono che i mitocondri sono uno dei primi target a rispondere all’infiammazione. Come dimostrato da indagini di microscopia time-lapse, l’infiammazione induce alterazioni delle dinamiche e della morfologia mitocondriali, con formazione di cluster mitocondriali perinucleari. Questi fenomeni sono accompagnati da un incremento nella produzione di ROS e dall’induzione di autofagia. Tuttavia le alterazioni sopra descritte sono transienti, dal momento esse si risolvono nell’arco di 24-48h. In particolare, la rimozione dell’autofagia determina l’impossibilità da parte degli astrociti di ripristinare una corretta funzionalità mitocondriale in seguito ad infiammazione, indice del fatto che l’autofagia svolge un ruolo-chiave nel quality control dei mitocondri in questo modello. Abbiamo inoltre investigato gli effetti mediati dagli astrociti sulla vitalità neuronale in un sistema di co-culture, e abbiamo osservato che l’infiammazione induce neurotossicità: lo stesso effetto viene a mancare se si effettua l’aggiunta di mezzo condizionato da astrociti infiammati su colture pure di neuroni, suggerendo che nel nostro modello il contatto diretto tra astrociti e neuroni è fondamentale per indurre disfunzione neuronale a seguito di infiammazione. Nell’insieme, questi dati sugggeriscono che l’infiammazione induce alterazioni temporanee della funzionalità mitocondriali associate ad autofagia.
Banga, Surinderjit. "Investigating role strain, coping and subjective well-being in combining multiple roles". Thesis, University of Plymouth, 1997. http://hdl.handle.net/10026.1/2163.
Texto completoCervantes, Cynthia Crystal y Vanessa Vazquez. "Knowledge of School Resource Officer's Roles and Their Perceptions on School Social Worker's Roles". CSUSB ScholarWorks, 2018. https://scholarworks.lib.csusb.edu/etd/716.
Texto completoAndersson, Ellen. "Är chefen en kvinna? : Högskolestudenters attityder till kvinnor som chefer". Thesis, Mälardalens högskola, Akademin för hälsa, vård och välfärd, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-35974.
Texto completoKarlsson, Nordqvist Rebekka. "Gender Roles Via Hedging in Children’s Films". Thesis, Högskolan i Gävle, Avdelningen för humaniora, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-16216.
Texto completoRees, Teresa. "The reproduction of gender segregation in the labour market". Thesis, Cardiff University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259986.
Texto completoVanEvery, Joanne. "Anti-sexist living arrangements : a feminist research project". Thesis, University of Essex, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386026.
Texto completoRosângela, David Bastos Lúcia. "Integration of system requirements and multiagent software architecture". Universidade Federal de Pernambuco, 2005. https://repositorio.ufpe.br/handle/123456789/2121.
Texto completoEngenharia de Requisitos e Arquitetura de Software vêm estabelecendo áreas de pesquisa, educação e pratica dentro da comunidade de Engenharia de Software. A evolução dessas duas disciplinas vem, entretanto, ocorrendo de forma independente, o que estabelece um problema de integração entre as duas disciplinas a ser explorada. A Engenharia de Requisitos identifica o propósito de sistemas e o contexto no qual serão utilizados. Arquitetura de Software define os componentes do software, suas propriedades e seus relacionamentos. Adicionalmente, Arquitetura de Software é reconhecida por ter grande importância no atendimento dos requisitos não-funcionais, tais como: disponibilidade, confidencialidade, manutenabilidade, segurança e evolução do sistema. Há um relacionamento claro entre as duas disciplinas, apesar disso, desenvolver requisitos de sistemas dentro de arquiteturas de software que satisfaçam àqueles requisitos é ainda uma tarefa difícil, baseada principalmente na intuição. Entender e dar suporte à integração entre os conceitos de requisitos e arquiteturas é um dos principais problemas nas pesquisas da Engenharia de Software. Para reduzir estes problemas, este tese propõe técnicas para derivar um modelo arquitetural a partir de especificações de requisitos em Sistema Multi-Agentes (MAS). Esta tese propõe uma estrutura para identificar e mapear os elementos arquiteturais e as dependências entre estes elementos, usando como base os requisitos declarados no sistema e conceitos organizacionais. Nossa abordagem propõe que um Sistema Multi-Agentes (MAS) corresponde a uma estrutura organizacional na qual os atores são membros de um grupo com o propósito de atingir um objetivo. Uma organização compreende grupos, membros, objetivos, papéis e interações. A idéia básica do conceito de grupo é fornecer uma referência coletiva de um conjunto de papéis que executam, de forma colaborativa um conjunto de tarefas para atingir os seus objetivos. Um membro, quando assume um papel, não trabalha isolado, mas interage e coopera com outros papéis. Nossa abordagem é baseada em dois modelos complementares que separam os conceitos de organização e de atribuição. No modelo organizacional, os objetivos do grupo são identificados a partir do modelo de requisitos do sistema. A organização social consiste em papéis e interações. No modelo da atribuição, os papéis são agrupados em sub-grupos. Estes sub-grupos são atribuídos aos componentes, baseados em sua similaridade com cada componente arquitetural. O resultado é uma configuração arquitetural, na qual os sub-grupos são alocados nos componentes da arquitetura
Lomurno, Maryellen. "Roles and expectations in inclusion /". Full text available online, 2005. http://www.lib.rowan.edu/home/research/articles/rowan_theses.
Texto completoTaing, Nguonly. "Run-time Variability with Roles". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-234933.
Texto completoL'Epicier-Sansregret, Laurent. "The cellular roles of CUX1". Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=94975.
Texto completoL'objectif initial de mon projet consistait à mettre au point divers tests permettant d'étudier le rôle du facteur de transcription à homéodomaine p110 CUX1 au cours du cycle cellulaire. J'ai d'abord observé que p110 CUX1 stimule la prolifération cellulaire lorsque exprimé de façon soutenue. À partir d'analyses par cytométrie en flux et de marquages au BrdU, j'ai démontré que l'expression de p110 CUX1 suscite une accélération de l'entrée en phase S. Cet effet s'est manifesté dans trois situations : à partir de la phase de quiescence (G0), à partir d'une synchronisation en G1/S et à partir de la phase G2/M lors d'un enrichissement par centrifugation à contre-courant (élutriation). En accord avec ces résultats, les fibroblastes murins isolé à partir d'embryons Cux-/- proliférèrent plus lentement par rapport aux fibroblastes Cux+/+ à cause d'une prolongation de la phase G1. J'ai identifié les gènes cycline E2 et cycline A2 comme deux cibles transcriptionnelles de p110 CUX1 pouvant expliquer son effet sur la transition G1/S. J'ai observé qu'il se développait une sous-population tétraploïde dans certaines lignées cellulaires exprimant p110 CUX1. Alors que la tétraploïdie cause généralement un arrêt de la prolifération ou la mort cellulaire dans les cellules normales, j'ai noté que l'expression de p110 CUX1 permettait aux cellules tétraploïdes d'avoir une division bipolaire normale malgré la présence de plusieurs centrosomes. J'ai démontré que cet effet était dû à la capacité de p110 CUX1 d'induire la transcription de plusieurs gènes permettant une activation efficace et prolongée du point de contrôle mitotique. J'ai établi un lien entre l'instabilité génomique des cellules tetraploïdes exprimant p110 CUX1 et l'acquisition de caractéristiques tumorales. De plus, j'ai noté que plus de 80% des cellules de tumeurs mammaires provenant de souris transgéniques CUX1 sont quasi tétraploïdes. Je propose donc un nou
Horn, Katherine. "Synaptic roles for developmental cues". Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116906.
Texto completoLe rôle des protéines impliquées dans le guidage des axones durant le développement du système nerveux est bien établi. Toutefois, même après le développement, dans le système nerveux central mature, plusieurs de ces molécules sont exprimées, incluant le signal moléculaire nétrine-1, et son récepteur Deleted in Colorectal Cancer (DCC), ainsi que le signal moléculaire Receptor Protein Tyrosine Phosphatase σ (RPTPσ), ce qui suggère que ces protéines ont des rôles qui dépassent le développement.Dans cette thèse, on explore la fonction du récepteur DCC dans la modulation synaptique. On aborde le rôle de DCC dans la ramification des extensions des neurones, ce qui a une conséquence sur la quantité de connexions synaptiques qui peuvent se former, et on établi que DCC est important pour la ramification causée par nétrine-1, en utilisant des mécanismes qui peuvent être indépendants de l'extension des axones. Dans le système nerveux central mature, DCC est enrichi aux synapses. En utilisant des souris transgéniques pour lesquelles DCC est supprimé des neurones du prosencéphale une fois le guidage des axones complété, on démontre que DCC contrôle la taille des épines sur les dendrites et qu'il est requis pour la mémoire spatiale et la mémoire de la reconnaisance. En effet, nos études d'électrophysiologie montrent que les souris déficientes en DCC ont de la difficulté à former la potentialisation à long terme (PLT). Elles ont aussi une baisse dans l'activation des kinases de la famille Src, ce qui coïncide avec l'implication connue de ces kinases dans la régulation des récepteurs NMDA (NMDARs) pour permettre la PLT. La déficience en PLT peut être récupérée par la facilitation des NMDARs suite à des modifications mineures de la solution extracellulaire utilisée lors de l'enregistrement de données, ou par l'activation pharmacologique de Src. Donc, on conclut que DCC contrôle l'induction de PLT par un mécanisme établi qui inclut l'activation de Src pour moduler la fonction de NMDAR.RPTPσ, un autre signal moléculaire impliqué dans le développement, a aussi été trouvé enrichi dans les membranes synaptiques du cerveau adulte. En utilisant des souris transgéniques qui n'expriment pas RPTPσ, on découvre que dans le cerveau mature, RPTPσ restreint les germes aberrants des axones, réglemente la densité des épines in vitro et in vivo, influence les propriétés synaptiques des cellules de l'hippocampe, et modifie la performance des souris dans les épreuves de comportement qui évaluent la mémoire de la reconnaissance. Ensemble, ces résultats suggèrent qu'il y a une augmentation des connexions synaptiques dans les souris déficientes en RPTPσ.En conclusion, on démontre que les protéines impliquées dans le guidage des axones pendant le développement ont des fonctions au-delà du développement, et que leurs expressions dans le système nerveux central mature contrôle la régulation synaptique dans le cerveau adulte.
周凱詩 y Hoi-sze Elsie Chow. "Globalisation and poverty: planners' roles". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31260779.
Texto completoVandegrift, Andrew. "Ecological Roles of Fungal Endophytes". Thesis, University of Oregon, 2016. http://hdl.handle.net/1794/20401.
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Fil: Martínez, Nicolás Sebastián. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.
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Texto completoGriffin, Roger J. "Novel biological roles for pyrimidines". Thesis, Aston University, 1986. http://publications.aston.ac.uk/12540/.
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