Acceder

Bibliografías temáticas / RNA viruses / Artículos de revistas

Siga este enlace para ver otros tipos de publicaciones sobre el tema: RNA viruses.

Artículos de revistas sobre el tema "RNA viruses"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 31 de julio de 2024

Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros

Elija tipo de fuente:

Consulte los 50 mejores artículos de revistas para su investigación sobre el tema "RNA viruses".

Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.

También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.

Explore artículos de revistas sobre una amplia variedad de disciplinas y organice su bibliografía correctamente.

1

Shi, Rui-Zhu, Yuan-Qing Pan y Li Xing. "RNA Helicase A Regulates the Replication of RNA Viruses". Viruses 13, n.º 3 (25 de febrero de 2021): 361. http://dx.doi.org/10.3390/v13030361.

Texto completo

Resumen

The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus replication. Herein, this review will provide an overview of the role of RHA in the replication of RNA viruses.

Los estilos APA, Harvard, Vancouver, ISO, etc.

2

Ahlquist, Paul. "Parallels among positive-strand RNA viruses, reverse-transcribing viruses and double-stranded RNA viruses". Nature Reviews Microbiology 4, n.º 5 (3 de abril de 2006): 371–82. http://dx.doi.org/10.1038/nrmicro1389.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

3

Sokoloski, Kevin J., Carol J. Wilusz y Jeffrey Wilusz. "Viruses: Overturning RNA Turnover". RNA Biology 3, n.º 4 (octubre de 2006): 140–44. http://dx.doi.org/10.4161/rna.3.4.4076.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

4

Yang, Jie, Hongjie Xia, Qi Qian y Xi Zhou. "RNA chaperones encoded by RNA viruses". Virologica Sinica 30, n.º 6 (diciembre de 2015): 401–9. http://dx.doi.org/10.1007/s12250-015-3676-2.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

5

Enami, Masayoshi. "Negative-strand RNA viruses. Reverse genetics of negative-strand RNA viruses." Uirusu 45, n.º 2 (1995): 145–57. http://dx.doi.org/10.2222/jsv.45.145.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

6

Ahlquist, P. "RNA-Dependent RNA Polymerases, Viruses, and RNA Silencing". Science 296, n.º 5571 (17 de mayo de 2002): 1270–73. http://dx.doi.org/10.1126/science.1069132.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

7

Newburn, Laura R. y K. Andrew White. "Trans-Acting RNA–RNA Interactions in Segmented RNA Viruses". Viruses 11, n.º 8 (14 de agosto de 2019): 751. http://dx.doi.org/10.3390/v11080751.

Texto completo

Resumen

RNA viruses represent a large and important group of pathogens that infect a broad range of hosts. Segmented RNA viruses are a subclass of this group that encode their genomes in two or more molecules and package all of their RNA segments in a single virus particle. These divided genomes come in different forms, including double-stranded RNA, coding-sense single-stranded RNA, and noncoding single-stranded RNA. Genera that possess these genome types include, respectively, Orbivirus (e.g., Bluetongue virus), Dianthovirus (e.g., Red clover necrotic mosaic virus) and Alphainfluenzavirus (e.g., Influenza A virus). Despite their distinct genomic features and diverse host ranges (i.e., animals, plants, and humans, respectively) each of these viruses uses trans-acting RNA–RNA interactions (tRRIs) to facilitate co-packaging of their segmented genome. The tRRIs occur between different viral genome segments and direct the selective packaging of a complete genome complement. Here we explore the current state of understanding of tRRI-mediated co-packaging in the abovementioned viruses and examine other known and potential functions for this class of RNA–RNA interaction.

Los estilos APA, Harvard, Vancouver, ISO, etc.

8

SATO, Hironori y Masaru YOKOYAMA. "RNA viruses and mutations". Uirusu 55, n.º 2 (2005): 221–29. http://dx.doi.org/10.2222/jsv.55.221.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

9

MINE, Akira y Tetsuro OKUNO. "Viruses and RNA silencing". Uirusu 58, n.º 1 (2008): 61–68. http://dx.doi.org/10.2222/jsv.58.61.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

10

Strauss, J. H. y E. G. Strauss. "Evolution of RNA Viruses". Annual Review of Microbiology 42, n.º 1 (octubre de 1988): 657–83. http://dx.doi.org/10.1146/annurev.mi.42.100188.003301.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

11

Carmichael, Gordon G. "Silencing viruses with RNA". Nature 418, n.º 6896 (julio de 2002): 379–80. http://dx.doi.org/10.1038/418379a.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

12

King, Andrew M. Q. "RNA viruses do it". Trends in Genetics 3 (enero de 1987): 60–61. http://dx.doi.org/10.1016/0168-9525(87)90173-9.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

13

Billiau, A. "Double-stranded RNA viruses". Antiviral Research 5, n.º 3 (junio de 1985): 191–92. http://dx.doi.org/10.1016/0166-3542(85)90052-x.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

14

Saiz, Juan-Carlos. "Vaccines against RNA Viruses". Vaccines 8, n.º 3 (27 de agosto de 2020): 479. http://dx.doi.org/10.3390/vaccines8030479.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

15

Slamon, Dennis J. y Irvin S. Y. Chen. "RNA viruses and cancer". Infectious Diseases Newsletter 5, n.º 4 (abril de 1986): 28–30. http://dx.doi.org/10.1016/0278-2316(86)90068-x.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

16

Hammarskjöld, Marie-Louise. "RNA and lessons from viruses". RNA 21, n.º 4 (16 de marzo de 2015): 632–33. http://dx.doi.org/10.1261/rna.050310.115.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

17

Lundstrom, Kenneth. "Self-Replicating RNA Viruses for RNA Therapeutics". Molecules 23, n.º 12 (13 de diciembre de 2018): 3310. http://dx.doi.org/10.3390/molecules23123310.

Texto completo

Resumen

Self-replicating single-stranded RNA viruses such as alphaviruses, flaviviruses, measles viruses, and rhabdoviruses provide efficient delivery and high-level expression of therapeutic genes due to their high capacity of RNA replication. This has contributed to novel approaches for therapeutic applications including vaccine development and gene therapy-based immunotherapy. Numerous studies in animal tumor models have demonstrated that self-replicating RNA viral vectors can generate antibody responses against infectious agents and tumor cells. Moreover, protection against challenges with pathogenic Ebola virus was obtained in primates immunized with alphaviruses and flaviviruses. Similarly, vaccinated animals have been demonstrated to withstand challenges with lethal doses of tumor cells. Furthermore, clinical trials have been conducted for several indications with self-amplifying RNA viruses. In this context, alphaviruses have been subjected to phase I clinical trials for a cytomegalovirus vaccine generating neutralizing antibodies in healthy volunteers, and for antigen delivery to dendritic cells providing clinically relevant antibody responses in cancer patients, respectively. Likewise, rhabdovirus particles have been subjected to phase I/II clinical trials showing good safety and immunogenicity against Ebola virus. Rhabdoviruses have generated promising results in phase III trials against Ebola virus. The purpose of this review is to summarize the achievements of using self-replicating RNA viruses for RNA therapy based on preclinical animal studies and clinical trials in humans.

Los estilos APA, Harvard, Vancouver, ISO, etc.

18

Lundstrom, Kenneth. "Self-Amplifying RNA Viruses as RNA Vaccines". International Journal of Molecular Sciences 21, n.º 14 (20 de julio de 2020): 5130. http://dx.doi.org/10.3390/ijms21145130.

Texto completo

Resumen

Single-stranded RNA viruses such as alphaviruses, flaviviruses, measles viruses and rhabdoviruses are characterized by their capacity of highly efficient self-amplification of RNA in host cells, which make them attractive vehicles for vaccine development. Particularly, alphaviruses and flaviviruses can be administered as recombinant particles, layered DNA/RNA plasmid vectors carrying the RNA replicon and even RNA replicon molecules. Self-amplifying RNA viral vectors have been used for high level expression of viral and tumor antigens, which in immunization studies have elicited strong cellular and humoral immune responses in animal models. Vaccination has provided protection against challenges with lethal doses of viral pathogens and tumor cells. Moreover, clinical trials have demonstrated safe application of RNA viral vectors and even promising results in rhabdovirus-based phase III trials on an Ebola virus vaccine. Preclinical and clinical applications of self-amplifying RNA viral vectors have proven efficient for vaccine development and due to the presence of RNA replicons, amplification of RNA in host cells will generate superior immune responses with significantly reduced amounts of RNA delivered. The need for novel and efficient vaccines has become even more evident due to the global COVID-19 pandemic, which has further highlighted the urgency in challenging emerging diseases.

Los estilos APA, Harvard, Vancouver, ISO, etc.

19

Raj, Pushker. "Classification of medically important viruses II: RNA viruses". Clinical Microbiology Newsletter 16, n.º 17 (septiembre de 1994): 129–34. http://dx.doi.org/10.1016/0196-4399(94)90005-1.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

20

Fisher, Susie. "Are RNA Viruses Vestiges of an RNA World?" Journal for General Philosophy of Science 41, n.º 1 (25 de mayo de 2010): 121–41. http://dx.doi.org/10.1007/s10838-010-9119-8.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

21

Geng, Guowei, Deya Wang, Zhifei Liu, Yalan Wang, Mingjing Zhu, Xinran Cao, Chengming Yu y Xuefeng Yuan. "Translation of Plant RNA Viruses". Viruses 13, n.º 12 (13 de diciembre de 2021): 2499. http://dx.doi.org/10.3390/v13122499.

Texto completo

Resumen

Plant RNA viruses encode essential viral proteins that depend on the host translation machinery for their expression. However, genomic RNAs of most plant RNA viruses lack the classical characteristics of eukaryotic cellular mRNAs, such as mono-cistron, 5′ cap structure, and 3′ polyadenylation. To adapt and utilize the eukaryotic translation machinery, plant RNA viruses have evolved a variety of translation strategies such as cap-independent translation, translation recoding on initiation and termination sites, and post-translation processes. This review focuses on advances in cap-independent translation and translation recoding in plant viruses.

Los estilos APA, Harvard, Vancouver, ISO, etc.

22

Silva-Júnior, Edeildo F. da. "Entry Inhibitors of RNA Viruses". Current Medicinal Chemistry 29, n.º 4 (febrero de 2022): 609–11. http://dx.doi.org/10.2174/092986732904220207113503.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

23

Pompei, Simone, Vittorio Loreto y Francesca Tria. "Phylogenetic Properties of RNA Viruses". PLoS ONE 7, n.º 9 (20 de septiembre de 2012): e44849. http://dx.doi.org/10.1371/journal.pone.0044849.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

24

Simon-Loriere, Etienne y Edward C. Holmes. "Why do RNA viruses recombine?" Nature Reviews Microbiology 9, n.º 8 (4 de julio de 2011): 617–26. http://dx.doi.org/10.1038/nrmicro2614.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

25

Steinhauer, D. A. y J. J. Holland. "Rapid Evolution of RNA Viruses". Annual Review of Microbiology 41, n.º 1 (octubre de 1987): 409–31. http://dx.doi.org/10.1146/annurev.mi.41.100187.002205.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

26

Gillespie, J. H. "Episodic evolution of RNA viruses." Proceedings of the National Academy of Sciences 90, n.º 22 (15 de noviembre de 1993): 10411–12. http://dx.doi.org/10.1073/pnas.90.22.10411.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

27

Zeller, Mark y Kristian G. Andersen. "Backbone of RNA viruses uncovered". Nature 556, n.º 7700 (abril de 2018): 182–83. http://dx.doi.org/10.1038/d41586-018-03923-w.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

28

Said, Elias A., Felipe Diaz-Griffero, Dorine Bonte, Daniel Lamarre y Ali A. Al-Jabri. "Immune Responses to RNA Viruses". Journal of Immunology Research 2018 (12 de junio de 2018): 1–2. http://dx.doi.org/10.1155/2018/5473678.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

29

Russell, Stephen J. "RNA viruses as virotherapy agents". Cancer Gene Therapy 9, n.º 12 (22 de noviembre de 2002): 961–66. http://dx.doi.org/10.1038/sj.cgt.7700535.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

30

Woodland, David L. "A Focus on RNA Viruses". Viral Immunology 24, n.º 2 (abril de 2011): 67–68. http://dx.doi.org/10.1089/vim.2011.ed.24.2.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

31

Rima, B. K. "Viruses in the RNA World". Biochemical Society Transactions 24, n.º 1 (1 de febrero de 1996): 1–13. http://dx.doi.org/10.1042/bst0240001.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

32

BHUVANESHWARI, M., H. SUBRAMANYA, M. MURTHY, K. GOPINATH y H. SAVITHRI. "Architecture of small RNA viruses". Progress in Crystal Growth and Characterization of Materials 34, n.º 1-4 (1997): 1–10. http://dx.doi.org/10.1016/s0960-8974(97)00001-6.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

33

Michalakis, Y. "EVOLUTION: Epistasis in RNA Viruses". Science 306, n.º 5701 (26 de noviembre de 2004): 1492–93. http://dx.doi.org/10.1126/science.1106677.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

34

Colbère-Garapin, Florence, Bruno Blondel, Aure Saulnier, Isabelle Pelletier y Karine Labadie. "Silencing viruses by RNA interference". Microbes and Infection 7, n.º 4 (abril de 2005): 767–75. http://dx.doi.org/10.1016/j.micinf.2005.02.003.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

35

Ruigrok, R. W. H. "Assembly of enveloped RNA viruses". FEBS Letters 202, n.º 1 (23 de junio de 1986): 159. http://dx.doi.org/10.1016/0014-5793(86)80670-6.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

36

Lang, Andrew S., Matthew L. Rise, Alexander I. Culley y Grieg F. Steward. "RNA viruses in the sea". FEMS Microbiology Reviews 33, n.º 2 (marzo de 2009): 295–323. http://dx.doi.org/10.1111/j.1574-6976.2008.00132.x.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

37

Drake, J. W. y J. J. Holland. "Mutation rates among RNA viruses". Proceedings of the National Academy of Sciences 96, n.º 24 (23 de noviembre de 1999): 13910–13. http://dx.doi.org/10.1073/pnas.96.24.13910.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

38

Dadley-Moore, Davina. "RNA viruses: all bases covered?" Nature Reviews Immunology 6, n.º 5 (mayo de 2006): 341. http://dx.doi.org/10.1038/nri1856.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

39

Rossmann, Michael G. "The evolution of RNA viruses". BioEssays 7, n.º 3 (septiembre de 1987): 99–103. http://dx.doi.org/10.1002/bies.950070302.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

40

Weber, Friedemann, Valentina Wagner, Simon B. Rasmussen, Rune Hartmann y Søren R. Paludan. "Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses". Journal of Virology 80, n.º 10 (15 de mayo de 2006): 5059–64. http://dx.doi.org/10.1128/jvi.80.10.5059-5064.2006.

Texto completo

Resumen

ABSTRACT Double-stranded RNA (dsRNA) longer than 30 bp is a key activator of the innate immune response against viral infections. It is widely assumed that the generation of dsRNA during genome replication is a trait shared by all viruses. However, to our knowledge, no study exists in which the production of dsRNA by different viruses is systematically investigated. Here, we investigated the presence and localization of dsRNA in cells infected with a range of viruses, employing a dsRNA-specific antibody for immunofluorescence analysis. Our data revealed that, as predicted, significant amounts of dsRNA can be detected for viruses with a genome consisting of positive-strand RNA, dsRNA, or DNA. Surprisingly, however, no dsRNA signals were detected for negative-strand RNA viruses. Thus, dsRNA is indeed a general feature of most virus groups, but negative-strand RNA viruses appear to be an exception to that rule.

Los estilos APA, Harvard, Vancouver, ISO, etc.

41

Chao, Shufen, Haoran Wang, Shu Zhang, Guoqing Chen, Chonghui Mao, Yang Hu, Fengquan Yu et al. "Novel RNA Viruses Discovered in Weeds in Rice Fields". Viruses 14, n.º 11 (10 de noviembre de 2022): 2489. http://dx.doi.org/10.3390/v14112489.

Texto completo

Resumen

Weeds often grow alongside crop plants. In addition to competing with crops for nutrients, water and space, weeds host insect vectors or act as reservoirs for viral diversity. However, little is known about viruses infecting rice weeds. In this work, we used metatranscriptomic deep sequencing to identify RNA viruses from 29 weed samples representing 23 weed species. A total of 224 RNA viruses were identified: 39 newly identified viruses are sufficiently divergent to comprise new families and genera. The newly identified RNA viruses clustered within 18 viral families. Of the identified viruses, 196 are positive-sense single-stranded RNA viruses, 24 are negative-sense single-stranded RNA viruses and 4 are double-stranded RNA viruses. We found that some novel RNA viruses clustered within the families or genera of several plant virus species and have the potential to infect plants. Collectively, these results expand our understanding of viral diversity in rice weeds. Our work will contribute to developing effective strategies with which to manage the spread and epidemiology of plant viruses.

Los estilos APA, Harvard, Vancouver, ISO, etc.

42

Richaud, Aurélien, Lise Frézal, Stephen Tahan, Hongbing Jiang, Joshua A. Blatter, Guoyan Zhao, Taniya Kaur, David Wang y Marie-Anne Félix. "Vertical transmission in Caenorhabditis nematodes of RNA molecules encoding a viral RNA-dependent RNA polymerase". Proceedings of the National Academy of Sciences 116, n.º 49 (18 de noviembre de 2019): 24738–47. http://dx.doi.org/10.1073/pnas.1903903116.

Texto completo

Resumen

Here, we report on the discovery in Caenorhabditis nematodes of multiple vertically transmitted RNAs coding for putative RNA-dependent RNA polymerases. Their sequences share similarity to distinct RNA viruses, including bunyaviruses, narnaviruses, and sobemoviruses. The sequences are present exclusively as RNA and are not found in DNA form. The RNAs persist in progeny after bleach treatment of adult animals, indicating vertical transmission of the RNAs. We tested one of the infected strains for transmission to an uninfected strain and found that mating of infected animals with uninfected animals resulted in infected progeny. By in situ hybridization, we detected several of these RNAs in the cytoplasm of the male and female germline of the nematode host. The Caenorhabditis hosts were found defective in degrading exogenous double-stranded RNAs, which may explain retention of viral-like RNAs. Strikingly, one strain, QG551, harbored three distinct virus-like RNA elements. Specific patterns of small RNAs complementary to the different viral-like RNAs were observed, suggesting that the different RNAs are differentially recognized by the RNA interference (RNAi) machinery. While vertical transmission of viruses in the family Narnaviridae, which are known as capsidless viruses, has been described in fungi, these observations provide evidence that multicellular animal cells harbor similar viruses.

Los estilos APA, Harvard, Vancouver, ISO, etc.

43

Yang, Siwy Ling, Riccardo Delli Ponti, Yue Wan y Roland G. Huber. "Computational and Experimental Approaches to Study the RNA Secondary Structures of RNA Viruses". Viruses 14, n.º 8 (16 de agosto de 2022): 1795. http://dx.doi.org/10.3390/v14081795.

Texto completo

Resumen

Most pandemics of recent decades can be traced to RNA viruses, including HIV, SARS, influenza, dengue, Zika, and SARS-CoV-2. These RNA viruses impose considerable social and economic burdens on our society, resulting in a high number of deaths and high treatment costs. As these RNA viruses utilize an RNA genome, which is important for different stages of the viral life cycle, including replication, translation, and packaging, studying how the genome folds is important to understand virus function. In this review, we summarize recent advances in computational and high-throughput RNA structure-mapping approaches and their use in understanding structures within RNA virus genomes. In particular, we focus on the genome structures of the dengue, Zika, and SARS-CoV-2 viruses due to recent significant outbreaks of these viruses around the world.

Los estilos APA, Harvard, Vancouver, ISO, etc.

44

Boonrod, Kajohn y Gabriele Krczal. "Inhibitions of Positive-Sense (ss) RNA Viruses RNA-Dependent RNA Polymerases". Current Enzyme Inhibition 5, n.º 4 (1 de diciembre de 2009): 234–44. http://dx.doi.org/10.2174/157340809789630262.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

45

Nicholson, Beth L. y K. Andrew White. "Functional long-range RNA–RNA interactions in positive-strand RNA viruses". Nature Reviews Microbiology 12, n.º 7 (16 de junio de 2014): 493–504. http://dx.doi.org/10.1038/nrmicro3288.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

46

Swaminathan, Gokul, Julio Martin-Garcia y Sonia Navas-Martin. "RNA viruses and microRNAs: challenging discoveries for the 21st century". Physiological Genomics 45, n.º 22 (15 de noviembre de 2013): 1035–48. http://dx.doi.org/10.1152/physiolgenomics.00112.2013.

Texto completo

Resumen

RNA viruses represent the predominant cause of many clinically relevant viral diseases in humans. Among several evolutionary advantages acquired by RNA viruses, the ability to usurp host cellular machinery and evade antiviral immune responses is imperative. During the past decade, RNA interference mechanisms, especially microRNA (miRNA)-mediated regulation of cellular protein expression, have revolutionized our understanding of host-viral interactions. Although it is well established that several DNA viruses express miRNAs that play crucial roles in their pathogenesis, expression of miRNAs by RNA viruses remains controversial. However, modulation of the miRNA machinery by RNA viruses may confer multiple benefits for enhanced viral replication and survival in host cells. In this review, we discuss the current literature on RNA viruses that may encode miRNAs and the varied advantages of engineering RNA viruses to express miRNAs as potential vectors for gene therapy. In addition, we review how different families of RNA viruses can alter miRNA machinery for productive replication, evasion of antiviral immune responses, and prolonged survival. We underscore the need to further explore the complex interactions of RNA viruses with host miRNAs to augment our understanding of host-virus interplay.

Los estilos APA, Harvard, Vancouver, ISO, etc.

47

Kolakofsky, Daniel. "A short biased history of RNA viruses". RNA 21, n.º 4 (16 de marzo de 2015): 667–69. http://dx.doi.org/10.1261/rna.049916.115.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

48

Ortín, Juan y Jaime Martín-Benito. "The RNA synthesis machinery of negative-stranded RNA viruses". Virology 479-480 (mayo de 2015): 532–44. http://dx.doi.org/10.1016/j.virol.2015.03.018.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

49

Wang, Wenqing, Xianhong Wang, Chunyan Tu, Mengmeng Yang, Jun Xiang, Liping Wang, Ni Hong, Lifeng Zhai y Guoping Wang. "Novel Mycoviruses Discovered from a Metatranscriptomics Survey of the Phytopathogenic Alternaria Fungus". Viruses 14, n.º 11 (18 de noviembre de 2022): 2552. http://dx.doi.org/10.3390/v14112552.

Texto completo

Resumen

Alternaria fungus can cause notable diseases in cereals, ornamental plants, vegetables, and fruits around the world. To date, an increasing number of mycoviruses have been accurately and successfully identified in this fungus. In this study, we discovered mycoviruses from 78 strains in 6 species of the genus Alternaria, which were collected from 10 pear production areas using high-throughput sequencing technology. Using the total RNA-seq, we detected the RNA-dependent RNA polymerase of 19 potential viruses and the coat protein of two potential viruses. We successfully confirmed these viruses using reverse transcription polymerase chain reaction with RNA as the template. We identified 12 mycoviruses that were positive-sense single-stranded RNA (+ssRNA) viruses, 5 double-strand RNA (dsRNA) viruses, and 4 negative single-stranded RNA (−ssRNA) viruses. In these viruses, five +ssRNA and four −ssRNA viruses were novel mycoviruses classified into diverse the families Botourmiaviridae, Deltaflexivirus, Mymonaviridea, and Discoviridae. We identified a novel −ssRNA mycovirus isolated from an A. tenuissima strain HB-15 as Alternaria tenuissima negative-stranded RNA virus 2 (AtNSRV2). Additionally, we characterized a novel +ssRNA mycovirus isolated from an A. tenuissima strain SC-8 as Alternaria tenuissima deltaflexivirus 1 (AtDFV1). According to phylogenetic and sequence analyses, we determined that AtNSRV2 was related to the viruses of the genus Sclerotimonavirus in the family Mymonaviridae. We also found that AtDFV1 was related to the virus family Deltaflexivirus. This study is the first to use total RNA sequencing to characterize viruses in Alternaria spp. These results expand the number of Alternaria viruses and demonstrate the diversity of these mycoviruses.

Los estilos APA, Harvard, Vancouver, ISO, etc.

50

Bwalya, John y Kook-Hyung Kim. "The Crucial Role of Chloroplast-Related Proteins in Viral Genome Replication and Host Defense against Positive-Sense Single-Stranded RNA Viruses". Plant Pathology Journal 39, n.º 1 (1 de febrero de 2023): 28–38. http://dx.doi.org/10.5423/ppj.rw.10.2022.0139.

Texto completo

Resumen

Plant viruses are responsible for worldwide production losses of numerous economically important crops. The most common plant RNA viruses are positivesense single-stranded RNA viruses [(+)ss RNA viruses]. These viruses have small genomes that encode a limited number of proteins. The viruses depend on their host’s machinery for the replication of their RNA genome, assembly, movement, and attraction to the vectors for dispersal. Recently researchers have reported that chloroplast proteins are crucial for replicating (+)ss plant RNA viruses. Some chloroplast proteins, including translation initiation factor [eIF(iso)4E] and 75 DEAD-box RNA helicase RH8, help viruses fulfill their infection cycle in plants. In contrast, other chloroplast proteins such as PAP2.1, PSaC, and ATPsyn-α play active roles in plant defense against viruses. This is also consistent with the idea that reactive oxygen species, salicylic acid, jasmonic acid, and abscisic acid are produced in chloroplast. However, knowledge of molecular mechanisms and functions underlying these chloroplast host factors during the virus infection is still scarce and remains largely unknown. Our review briefly summarizes the latest knowledge regarding the possible role of chloroplast in plant virus replication, emphasizing chloroplast-related proteins. We have highlighted current advances regarding chloroplast-related proteins’ role in replicating plant (+)ss RNA viruses.

Los estilos APA, Harvard, Vancouver, ISO, etc.

Ofrecemos descuentos en todos los planes premium para autores cuyas obras están incluidas en selecciones literarias temáticas. ¡Contáctenos para obtener un código promocional único!