Literatura académica sobre el tema "RNA localization and translation"
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Artículos de revistas sobre el tema "RNA localization and translation"
Gáspár, Imre y Anne Ephrussi. "RNA localization feeds translation". Science 357, n.º 6357 (21 de septiembre de 2017): 1235–36. http://dx.doi.org/10.1126/science.aao5796.
Texto completoGavis, E. R., L. Lunsford, S. E. Bergsten y R. Lehmann. "A conserved 90 nucleotide element mediates translational repression of nanos RNA". Development 122, n.º 9 (1 de septiembre de 1996): 2791–800. http://dx.doi.org/10.1242/dev.122.9.2791.
Texto completoLasko, Paul. "Cup-ling oskar RNA localization and translational control". Journal of Cell Biology 163, n.º 6 (22 de diciembre de 2003): 1189–91. http://dx.doi.org/10.1083/jcb.200311123.
Texto completoRongo, C., E. R. Gavis y R. Lehmann. "Localization of oskar RNA regulates oskar translation and requires Oskar protein". Development 121, n.º 9 (1 de septiembre de 1995): 2737–46. http://dx.doi.org/10.1242/dev.121.9.2737.
Texto completoRosana, Albert Remus R., Denise S. Whitford, Richard P. Fahlman y George W. Owttrim. "Cyanobacterial RNA Helicase CrhR Localizes to the Thylakoid Membrane Region and Cosediments with Degradosome and Polysome Complexes in Synechocystis sp. Strain PCC 6803". Journal of Bacteriology 198, n.º 15 (23 de mayo de 2016): 2089–99. http://dx.doi.org/10.1128/jb.00267-16.
Texto completoMARZI, S. "Ribosomal localization of translation initiation factor IF2". RNA 9, n.º 8 (1 de agosto de 2003): 958–69. http://dx.doi.org/10.1261/rna.2116303.
Texto completoBergsten, S. E. y E. R. Gavis. "Role for mRNA localization in translational activation but not spatial restriction of nanos RNA". Development 126, n.º 4 (15 de febrero de 1999): 659–69. http://dx.doi.org/10.1242/dev.126.4.659.
Texto completoRajgor, Dipen y Catherine M. Shanahan. "RNA granules and cytoskeletal links". Biochemical Society Transactions 42, n.º 4 (1 de agosto de 2014): 1206–10. http://dx.doi.org/10.1042/bst20140067.
Texto completoMansfield, Jennifer H., James E. Wilhelm y Tulle Hazelrigg. "Ypsilon Schachtel, aDrosophilaY-box protein, acts antagonistically to Orb in theoskarmRNA localization and translation pathway". Development 129, n.º 1 (1 de enero de 2002): 197–209. http://dx.doi.org/10.1242/dev.129.1.197.
Texto completoAnderson, Paul y Nancy Kedersha. "RNA granules". Journal of Cell Biology 172, n.º 6 (6 de marzo de 2006): 803–8. http://dx.doi.org/10.1083/jcb.200512082.
Texto completoTesis sobre el tema "RNA localization and translation"
Ciolli, Mattioli Camilla. "Post-transcriptional mechanisms contributing to RNA and protein localization: study of local translation and alternative 3′UTRs in induced neurons". Doctoral thesis, Humboldt-Universität zu Berlin, 2019. http://dx.doi.org/10.18452/20702.
Texto completoAsymmetric distribution of mRNA and proteins inside a cell defines polarity, which allow tight regulation of gene expression in space and time. In this thesis I investigated how asymmetric distribution characterizes the somatic and neuritic compartments of in induced neurons, in terms of transcriptome and translatome. Spatial ribosome profiling analysis revealed that half of the local proteome is defined by mRNA localization and local translation. These, are processes accomplished by the synergistic activity of trans- and cis-acting elements. I focused on MOV10 as trans-acting element, and on alternative 3′UTRs as cis-elements, to investigate their role in asymmetry. MOV10 is an RNA helicase which participates to many aspects of RNA metabolism. With RIP and PAR-CLIP I showed that MOV10 targets are localized to the neurites, consistently with MOV10-neuritic localization, and that MOV10 might be involved in translational repression. Indeed, among MOV10 protein interactors, I identified several proteins involved in translational repression, i.e. AGO2, FMR1, and TRIM71. On the side of cis-elements, I performed mapping of alternative 3′UTRs. This analysis identified several genes expressing differentially localized 3′UTR isoforms. In particular, I focused on Cdc42. I showed that the two isoforms of Cdc42 are differentially localized at mRNA level, and that the 3′UTR is the driver of mRNA and protein localization. Moreover, I identified several RBPs that might be involved in Cdc42 localization. This analysis points to usage of alternative 3′UTR isoforms as a novel mechanism to provide for differential localization of functionally diverse alternative protein isoforms.
Rongo, Christopher Gabriel. "The role of RNA localization and translational regulation in Drosophila germ cell determination". Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/10562.
Texto completoVicario, Annalisa. "Analysis of the molecular mechanisms of BDNF mRNA localization and traslation in neurons". Doctoral thesis, Università degli studi di Trieste, 2010. http://hdl.handle.net/10077/3664.
Texto completoLa regolazione dell’espressione genica rappresenta uno fenomeno fondamentale per garantire la sopravvivenza e la corretta funzione cellulare. In strutture complesse ed altamente specializzate come il sistema nervoso, la grande varietà morfologica e funzionale, la rapidità di interscambio di comunicazioni e di adattamento richiede un’altrettanto fine regolazione spazio-temporale dell’espressione genica. I livelli di regolazione sono molteplici e includono lo splicing alternativo, la regolazione del turnover degli mRNA, modifiche post-traduzionali ed il controllo traduzionale. La segregazione dei trascritti in diversi compartimenti subcellulari rappresenta un ulteriore meccanismo che permette di concentrare le proteine in specifici domini cellulari mediante traduzione localizzata. A partire dagli anni ’80 sono stati scoperti numerosi mRNA a livello dendritico, tra cui i trascritti codificanti Brain Derived Neurotrophic Factor (BDNF) ed il suo recettore TrkB (Tongiorgi et al., 1997). L’mRNA per BDNF si localizza nei dendriti in risposta all‘attività elettrica e al BDNF in vitro e in seguito a crisi epilettogeniche indotte in vivo (Tongiorgi et al., 1997, 2004; Righi et al., 2000). La segregazione degli mRNA nei neuriti presuppone la potenziale traduzione in loco a seguito di specifici stimoli. A tal supporto vi è la dimostrazione della presenza di fattori coinvolti nella sintesi proteica (poliribosmi, tRNA, eIFs, eEFs, marker del reticolo endoplasmatico e del golgi) alla base delle spine dendritiche (Steward and Levi,1982; Tiedge and Brosius, 1996). Le dinamiche del trasporto coinvolgono elementi in trans, le RNA binding proteins, , ed elementi in cis, riconosciuti dalle proteine di trasporto. Questi ultimi sono solitamente confinati nella regione 3’UTR (Bashirullah et al., 1998), in misura inferiore all’interno della regione codificante (CDS) (Mohr, 1999; Chiaruttini et al., 2009) e dei 5’UTR (Muslimov et al., 1997). Tra le più comuni RBPs annoveriamo CPEB, ZBP, hnRNP, Staufen, FMRP, Translin e le proteine ELAV. Ricordiamo come molte di queste proteine di trasporto degli mRNA siano in realtà repressori della traduzione, al fine di prevenirne l’espressione ectopica durante il trasporto. Le RBPs che si legano all’mRNA di BDNF non sono ancora note, tuttavia nel corso di questo studio, mediante ibridazioni in situ non radioattiva su colture ippocampali/sezioni di cervello di topo è stata scoperta un serie di elementi in cis che regolano la localizzazione del trascritto. Alla luce dei risultati ottenuti, emerge un complesso quadro di regolazione post-trascrizionale e traduzionale di BDNF. L’RNA endogeno si localizza nel compartimento dendritico distale in seguito ad attività elettrica ed applicazione di BDNF od NT-3. I segnali di trasporto sensibili sono molteplici e distribuiti in diverse regioni dell’mRNA: un segnale costitutivo a carico della CDS(riconosciuto da translin), due segnali inducibili a livello del 3’UTR short (KCL ed NT-3, riconosciuti da CPEB1 e 2, ELAV2 e 4) ed altrettanti a livello 3’UTR long (KCl e BDNF, target di ELAV e CPEB), in aggiunta ad un segnale di ritenzione all’interno della stessa regione (osservato anche in topi KO per FXR2 ed FMRP). La modulazione del trasporto del 3’UTR long è di gran lunga più finemente regolata rispetto alla variante short, e ricorda il comportamento del 3’UTR della CaMKII (Mori et al., 2000), anch’esso coinvolto nella plasticità e potenziamento sinaptici. Dal punto di vista traduzionale, la distinzione tra 3’UTR short e long è netta: per quanto riguarda il primo, il meccanismo è piuttosto lineare e viene attivato dalla cascata del glutammato/Aurora chinasi/CPEB, mentre per il secondo, scarsamente traducibile, sembra sia necessaria la compresenza di più stimoli per attivarne la corretta traduzione, suggerendo come il 3’UTR long possa rappresentare un “coincidence detector“ che viene attivato solo in particolari contesti, a traccia di una complessa attività sinaptica. Dagli studi condotti siamo stati in grado di costruire un modello che possa spiegare come un trascritto così complesso possa rispondere a diversi stimoli. La CDS contiene un segnale di trasporto costitutivo mediato da translin, che in condizioni basali viene soppresso da un elemento inibitorio all’interno del 3’UTR long. In seguito ad attivazione viene meno la repressione in modo da favorire il trasporto del trascritto mediato dai due segnali di targeting (CDS e 3’long). Per quanto riguarda i trascritti contenenti la variante short, invece, sembra non vi siano segnali di ritenzione, bensì elementi di trasporto che vengono attivati in seguito ad uno specifico stimolo extracellulare (KCL od NT3).
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Ohler, Uwe [Gutachter], Florian [Gutachter] Heyd y Chakrabarti [Gutachter] Sutapa. "Post-transcriptional mechanisms contributing to RNA and protein localization: study of local translation and alternative 3′UTRs in induced neurons / Gutachter: Uwe Ohler, Florian Heyd, Chakrabarti Sutapa". Berlin : Humboldt-Universität zu Berlin, 2019. http://d-nb.info/1199930695/34.
Texto completoMaderazo, Alan Baer. "A Study on the Cellular Localization of Factors Involved in Yeast Nonsense-Mediated mRNA Decay and their Mechanisms of Control on Nonsense mRNA Translation: a Dissertation". eScholarship@UMMS, 2000. https://escholarship.umassmed.edu/gsbs_diss/105.
Texto completoEliscovich, Carolina. "Spindle-Localized CPE-Mediated Translation Controls Mediotic Chromosome Segregation". Doctoral thesis, Universitat Pompeu Fabra, 2008. http://hdl.handle.net/10803/7123.
Texto completoEn este trabajo que derivó en mi tesis doctoral, hemos demostrado que la activación traduccional localizada en el huso mitótico de mRNAs regulados por CPEB que codifican para proteinas con una conocida función en aspectos estructurales del ciclo celular como la formación del huso mitótico y la segregación cromosómica, es esencial para completar la primera división meiótica y para la correcta segregación cromosómica en oocitos de Xenopus.
Reynolds, Joanna Elizabeth. "Initiation of hepatitis C virus RNA translation". Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264546.
Texto completoHunt, Sarah Louise. "Cellular proteins required for rhinovirus RNA translation". Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313880.
Texto completoLempke, Carola. "Internal initiation of translation of cardiovirus RNA". Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624267.
Texto completoDonlevy, Alison. "Regulation of RNA translation by phenethyl isothiocyanate". Thesis, University of Southampton, 2013. https://eprints.soton.ac.uk/362491/.
Texto completoLibros sobre el tema "RNA localization and translation"
Maylath, Bruce y Kirk St.Amant, eds. Translation and Localization. London ; New York, NY : Routledge, 2019. |: Routledge, 2019. http://dx.doi.org/10.4324/9780429453670.
Texto completoRichter, Dietmar, ed. Cell Polarity and Subcellular RNA Localization. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-540-40025-7.
Texto completoDunne, Keiran J. y Elena S. Dunne, eds. Translation and Localization Project Management. Amsterdam: John Benjamins Publishing Company, 2011. http://dx.doi.org/10.1075/ata.xvi.
Texto completoPym, Anthony. The moving text: Localization, translation, and distribution. Amsterdam: Benjamins, 2003.
Buscar texto completoThe moving text: Localization, translation, and distribution. Amsterdam: John Benjamins Pub. Co., 2004.
Buscar texto completoTranslation and localization project management: The art of the possible. Amsterdam: John Benjamins Pub. Co., 2011.
Buscar texto completoDunne, Keiran J. Translation and localization project management: The art of the possible. Amsterdam: John Benjamins Pub. Co., 2011.
Buscar texto completo(Firm), Lingo Systems. The guide to translation and localization: Communicating with the global marketplace. 7a ed. Portland, OR: Lingo Systems, 2009.
Buscar texto completo(Firm), Lingo Systems, ed. The guide to translation and localization: Communicating with the global marketplace. 6a ed. [Portland, OR]: Lingo Systems, 2006.
Buscar texto completoJobling, S. A. In vitro and in vivo translation of tobacco ringspot virus RNA. Birmingham: University of Birmingham, 1985.
Buscar texto completoCapítulos de libros sobre el tema "RNA localization and translation"
Lin, Julie Qiaojin y Jean-Michel Cioni. "Live Imaging of RNA Transport and Translation in Xenopus Retinal Axons". En Methods in Molecular Biology, 49–69. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1990-2_3.
Texto completoVeyrune, J. L., J. Hesketh y J. M. Blanchard. "3´ Untranslated Regions of c-myc and c-fos mRNAs: Multifunctional Elements Regulating mRNA Translation, Degradation and Subcellular Localization". En Cytoplasmic fate of messenger RNA, 35–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60471-3_3.
Texto completoPięta, Hanna, Rita Bueno Maia y Ester Torres-Simón. "Localization". En Indirect Translation Explained, 78–108. London: Routledge, 2022. http://dx.doi.org/10.4324/9781003035220-4.
Texto completoBowker, Lynne. "Localization". En De-mystifying Translation, 111–26. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003217718-8.
Texto completoMoorthy, Balaji T. y Ralf-Peter Jansen. "mRNA Localization". En Fungal RNA Biology, 135–57. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-05687-6_6.
Texto completoJiménez-Crespo, Miguel A. "Localization". En Routledge Encyclopedia of Translation Studies, 299–305. 3a ed. Third edition. | London ; New York, NY : Routledge, 2019.: Routledge, 2019. http://dx.doi.org/10.4324/9781315678627-64.
Texto completoVanDyk, John K. "Localization and Translation". En Pro Drupal Development, 407–38. Berkeley, CA: Apress, 2008. http://dx.doi.org/10.1007/978-1-4302-0990-4_18.
Texto completoTomlinson, Todd y John K. VanDyk. "Localization and Translation". En Pro Drupal 7 Development, 417–49. Berkeley, CA: Apress, 2010. http://dx.doi.org/10.1007/978-1-4302-2839-4_19.
Texto completoSchäler, Reinhard. "Localization and translation". En Handbook of Translation Studies, 209–14. Amsterdam: John Benjamins Publishing Company, 2010. http://dx.doi.org/10.1075/hts.1.loc1.
Texto completoSvoboda, Tomáš. "Computing and Translation". En Translation and Localization, 181–218. London ; New York, NY : Routledge, 2019. |: Routledge, 2019. http://dx.doi.org/10.4324/9780429453670-9.
Texto completoActas de conferencias sobre el tema "RNA localization and translation"
Yao, Yazhi. "An Ontology-Based Translation Memory Model in Localization Translation". En 2010 International Symposium on Information Science and Engineering (ISISE). IEEE, 2010. http://dx.doi.org/10.1109/isise.2010.37.
Texto completoBLENCOWE, BENJAMIN, STEVEN BRENNER, TIMOTHY HUGHES y QUAID MORRIS. "POST-TRANSCRIPTIONAL GENE REGULATION: RNA-PROTEIN INTERACTIONS, RNA PROCESSING, MRNA STABILITY AND LOCALIZATION". En Proceedings of the Pacific Symposium. WORLD SCIENTIFIC, 2008. http://dx.doi.org/10.1142/9789812836939_0052.
Texto completoOrjalo, Arturo V. y Hans E. Johansson. "Abstract A2-44: Stellaris® RNA fluorescence in situ hybridization (RNA FISH) for the detection of long non coding RNA biomarkers". En Abstracts: AACR Special Conference: Translation of the Cancer Genome; February 7-9, 2015; San Francisco, CA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.transcagen-a2-44.
Texto completoLopes, Nuno G. y Carlos J. Costa. "ERP localization: exploratory study in translation". En the 26th annual ACM international conference. New York, New York, USA: ACM Press, 2008. http://dx.doi.org/10.1145/1456536.1456555.
Texto completoGirault, Benjamin, Paulo Goncalves, Shrikanth S. Narayanan y Antonio Ortega. "Localization bounds for the graph translation". En 2016 IEEE Global Conference on Signal and Information Processing (GlobalSIP). IEEE, 2016. http://dx.doi.org/10.1109/globalsip.2016.7905858.
Texto completoBelgacem, Ismail, Edith Grac, Delphine Ropers y Jean-Luc Gouze. "Stability analysis of a reduced transcription-translation model of RNA polymerase". En 2014 IEEE 53rd Annual Conference on Decision and Control (CDC). IEEE, 2014. http://dx.doi.org/10.1109/cdc.2014.7039999.
Texto completoHan, Sheng, Wei Gao, Yiming Wan y Yihong Wu. "Scene-Unified Image Translation For Visual Localization". En 2020 IEEE International Conference on Image Processing (ICIP). IEEE, 2020. http://dx.doi.org/10.1109/icip40778.2020.9190885.
Texto completoPerillo, Evan P., Leyma De Haro, Mary E. Phipps, Jennifer S. Martinez, Hsin-Chih Yeh, Andrew K. Dunn, Douglas P. Shepherd y James H. Werner. "Enhanced 3D localization of individual RNA transcripts via astigmatic imaging". En SPIE BiOS, editado por Jörg Enderlein, Ingo Gregor, Zygmunt K. Gryczynski, Rainer Erdmann y Felix Koberling. SPIE, 2014. http://dx.doi.org/10.1117/12.2038197.
Texto completoCharalampidou, Parthena. "The use of corpora in an interdisciplinary approach to localization". En TRanslation and Interpreting Technology ONline. INCOMA Ltd. Shoumen, BULGARIA, 2021. http://dx.doi.org/10.26615/978-954-452-071-7_025.
Texto completoLi, Qian. "On Localization Strategies of E-C Trademark Translation". En 2018 2nd International Conference on Education, Economics and Management Research (ICEEMR 2018). Paris, France: Atlantis Press, 2018. http://dx.doi.org/10.2991/iceemr-18.2018.162.
Texto completoInformes sobre el tema "RNA localization and translation"
Lapidot, Moshe y Vitaly Citovsky. molecular mechanism for the Tomato yellow leaf curl virus resistance at the ty-5 locus. United States Department of Agriculture, enero de 2016. http://dx.doi.org/10.32747/2016.7604274.bard.
Texto completoLoebenstein, Gad, William O. Dawson y Abed Gera. Further Characterization of IVR Isolation of its M-RNA, and its Relation to Localization and Necrotization. United States Department of Agriculture, agosto de 1986. http://dx.doi.org/10.32747/1986.7566706.bard.
Texto completoLoebenstein, Gad, William Dawson y Abed Gera. Association of the IVR Gene with Virus Localization and Resistance. United States Department of Agriculture, agosto de 1995. http://dx.doi.org/10.32747/1995.7604922.bard.
Texto completoCitovsky, Vitaly y Yedidya Gafni. Suppression of RNA Silencing by TYLCV During Viral Infection. United States Department of Agriculture, diciembre de 2009. http://dx.doi.org/10.32747/2009.7592126.bard.
Texto completoOstersetzer-Biran, Oren y Alice Barkan. Nuclear Encoded RNA Splicing Factors in Plant Mitochondria. United States Department of Agriculture, febrero de 2009. http://dx.doi.org/10.32747/2009.7592111.bard.
Texto completoElroy-Stein, Orna y Dmitry Belostotsky. Mechanism of Internal Initiation of Translation in Plants. United States Department of Agriculture, diciembre de 2010. http://dx.doi.org/10.32747/2010.7696518.bard.
Texto completoChamovitz, Daniel A. y Albrecht G. Von Arnim. eIF3 Complexes and the eIF3e Subunit in Arabidopsis Development and Translation Initiation. United States Department of Agriculture, septiembre de 2009. http://dx.doi.org/10.32747/2009.7696545.bard.
Texto completoStern, David y Gadi Schuster. Manipulation of Gene Expression in the Chloroplast. United States Department of Agriculture, septiembre de 2000. http://dx.doi.org/10.32747/2000.7575289.bard.
Texto completoStern, David B. y Gadi Schuster. Manipulation of Gene Expression in the Chloroplast: Control of mRNA Stability and Transcription Termination. United States Department of Agriculture, diciembre de 1993. http://dx.doi.org/10.32747/1993.7568750.bard.
Texto completoElizur, Abigail, Amir Sagi, Gideon Hulata, Clive Jones y Wayne Knibb. Improving Crustacean Aquaculture Production Efficiencies through Development of Monosex Populations Using Endocrine and Molecular Manipulations. United States Department of Agriculture, junio de 2010. http://dx.doi.org/10.32747/2010.7613890.bard.
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