Literatura académica sobre el tema "Respiratory chain"
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Artículos de revistas sobre el tema "Respiratory chain"
Schägger, Hermann. "Respiratory Chain Supercomplexes". IUBMB Life (International Union of Biochemistry and Molecular Biology: Life) 52, n.º 3-5 (1 de septiembre de 2001): 119–28. http://dx.doi.org/10.1080/15216540152845911.
Texto completoAmeyama, Minoru, Kazunobu Matsushita, Emiko Shinagawa y Osao Adachi. "Sugar-oxidizing Respiratory Chain ofGluconobacter suboxydans. Evidence for a Branched Respiratory Chain and Characterization of Respiratory Chain-Linked Cytochromes". Agricultural and Biological Chemistry 51, n.º 11 (noviembre de 1987): 2943–50. http://dx.doi.org/10.1080/00021369.1987.10868527.
Texto completoDiMauro, Salvatore y Eric A. Schon. "Mitochondrial Respiratory-Chain Diseases". New England Journal of Medicine 348, n.º 26 (26 de junio de 2003): 2656–68. http://dx.doi.org/10.1056/nejmra022567.
Texto completoRich, Peter R. y Amandine Maréchal. "The mitochondrial respiratory chain". Essays in Biochemistry 47 (14 de junio de 2010): 1–23. http://dx.doi.org/10.1042/bse0470001.
Texto completoAMEYAMA, Minoru, Kazunobu MATSUSHITA, Emiko SHINAGAWA y Osao ADACHI. "Sugar-oxidizing respiratory chain of Gluconobacter suboxydans. Evidence for a branched respiratory chain and characterization of respiratory chain-linked cytochromes." Agricultural and Biological Chemistry 51, n.º 11 (1987): 2943–50. http://dx.doi.org/10.1271/bbb1961.51.2943.
Texto completoMBBS, Joannie Hui, Denise M. Kirby, David R. Thorburn y A. vihu Boneh. "Decreased activities of mitochondrial respiratory chain complexes in non-mitochondrial respiratory chain diseases". Developmental Medicine & Child Neurology 48, n.º 2 (febrero de 2006): 132–36. http://dx.doi.org/10.1017/s0012162206000284.
Texto completoMeuric, Vincent, Astrid Rouillon, Fatiha Chandad y Martine Bonnaure-Mallet. "Putative respiratory chain ofPorphyromonas gingivalis". Future Microbiology 5, n.º 5 (mayo de 2010): 717–34. http://dx.doi.org/10.2217/fmb.10.32.
Texto completoShoubridge, Eric A. "Supersizing the Mitochondrial Respiratory Chain". Cell Metabolism 15, n.º 3 (marzo de 2012): 271–72. http://dx.doi.org/10.1016/j.cmet.2012.02.009.
Texto completoPfeiffer, Kathy, Vishal Gohil, Rosemary A. Stuart, Carola Hunte, Ulrich Brandt, Miriam L. Greenberg y Hermann Schägger. "Cardiolipin Stabilizes Respiratory Chain Supercomplexes". Journal of Biological Chemistry 278, n.º 52 (15 de octubre de 2003): 52873–80. http://dx.doi.org/10.1074/jbc.m308366200.
Texto completoZhang, Mei, Eugenia Mileykovskaya y William Dowhan. "Gluing the Respiratory Chain Together". Journal of Biological Chemistry 277, n.º 46 (2 de octubre de 2002): 43553–56. http://dx.doi.org/10.1074/jbc.c200551200.
Texto completoTesis sobre el tema "Respiratory chain"
Hansson, Anna. "Cellular responses to respiratory chain dysfunction /". Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-493-7/.
Texto completoSilva, José Pablo. "The pathophysiology of respiratory chain dysfunction /". Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-234-9/.
Texto completoLi, Xi. "The respiratory chain in Neisseria species". Thesis, University of York, 2013. http://etheses.whiterose.ac.uk/3989/.
Texto completoChen, Walter W. "Pathological features of mitochondrial respiratory chain dysfunction". Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104099.
Texto completoThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis. "June 2016."
Includes bibliographical references.
Mitochondria are essential organelles that carry out a multitude of important metabolic processes in mammalian organisms. These processes include ATP generation by the respiratory chain, aspartate synthesis by matrix aminotransferases, and long-chain fatty acid catabolism by the beta oxidation pathway. Given the role of mitochondria in maintaining cellular physiology, mitochondrial dysfunction often leads to disease. One major class of mitochondrial pathologies is caused by defects in the mitochondrial respiratory chain (RC). Yet while the genetic etiologies of these RC disorders are well-studied, the molecular defects that actually link RC dysfunction with impaired cellular viability are still unclear. In the work described here, we demonstrate that loss of mitochondrial membrane potential and aspartate contributes significantly to cellular pathology during RC dysfunction. In addition, we develop a novel method for rapidly isolating mitochondria and profiling their metabolite contents to study the changes in mitochondrial metabolism across various states of RC function. From this work, we find numerous alterations in matrix metabolites that had been previously unappreciated using traditional profiling of whole-cells and identify new metabolic abnormalities downstream of RC dysfunction. Collectively, this work uncovers distinct molecular events connecting RC pathology with impaired cellular viability and expands our understanding of the metabolic processes affected by RC dysfunction, thus opening up new areas for exploration.
by Walter W. Chen.
Ph. D.
Capristo, Mariantonietta <1981>. "Respiratory chain complex I dysfunction in tumorigenesis". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4798/1/Capristo_Mariantonietta_Tesi.pdf.
Texto completoCapristo, Mariantonietta <1981>. "Respiratory chain complex I dysfunction in tumorigenesis". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4798/.
Texto completoJackson, Margaret J. "Clinical and biochemical studies of respiratory chain disease". Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294642.
Texto completoHeiske, Margit. "Modeling the respiratory chain and the oxidative phosphorylation". Thesis, Bordeaux 2, 2012. http://www.theses.fr/2012BOR21965/document.
Texto completoLes mitochondries sont l’usine à énergie de la cellule. Elles synthétisent l’ATP à partir d’une succession de réactions d’oxydo-réduction catalysées par quatre complexes respiratoires qui forment la chaîne respiratoire. Avec la machinerie de synthèse d’ATP l’ensemble constitue les oxydations phosphorylantes (OXPHOS). Le but de ce travail est de bâtir un modèle des OXPHOS basé sur des équations de vitesse simples mais thermodynamiquement correctes, représentant l’activité des complexes de la chaîne respiratoire (équations de type Michaelis- Menten). Les paramètres cinétiques de ces équations sont identifiés en utilisant les cinétiques expérimentales de ces complexes respiratoires réalisées en absence de gradient de proton. La phase la plus délicate de ce travail a résidé dans l’introduction du gradient de protons dans ces équations. Nous avons trouvé que la meilleure manière était de distribuer l’effet du gradient de proton sous forme d’une loi exponentielle sur l’ensemble des paramètres, Vmax et Km pour les substrats et les produits. De cette manière, j’ai montré qu’il était possible de représenter les variations d’oxygène, de ΔΨ et de ΔpH trouvés dans la littérature. De plus, contrairement aux autres modèles, il fut possible de simuler les courbes de seuil observées expérimentalement lors de la titration du flux de respiration par l’inhibiteur d’un complexe respiratoire donné.Ce modèle pourra présenter un très grand intérêt pour comprendre le rôle de mieux en mieux reconnu des mitochondries dans de nombreux processus cellulaires, tels que la production d’espèces réactives de l’oxygène, le vieillissement, le diabète, le cancer, les pathologies mitochondriales etc. comme l’illustrent un certain nombre de prédictions présentées dans ce travail
Heiske, Margit. "Modeling the respiratory chain and the oxidative phosphorylation". Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2013. http://dx.doi.org/10.18452/16720.
Texto completoOxidative phosphorylation (OXPHOS) plays a central role in the cellular energy metabolism. It comprises the respiratory chain, consisting of four enzyme complexes that establish a proton gradient over the inner mitochondrial membrane, and the ATP-synthase that uses this electrochemical gradient to phosphorylate ADP to ATP, the cellular energy unit. In this work a thermodynamically consistent OXPHOS model was built based on a set of differential equations. Therefore rate equations were developed that describe the kinetics of each OXPHOS complex over a wide concentration range of substrates and products as well for various values of the electrochemical gradient. In a first step, kinetic measurements on bovine heart submitochondrial particles have been performed in the absence of the proton gradient. An appropriate data description was achieved with Michaelis-Menten like equations; here several types of equations have been compared. The next step consisted in incorporating the proton gradient into the rate equations. This was realized by distributing its influence among the kinetic parameters such that reasonable catalytic rates were obtained under physiological conditions. Finally, these new individual kinetic rate expressions for the OXPHOS complexes were integrated in a global model of oxidative phosphorylation. This new model could fit interrelated data of oxygen consumption, the transmembrane potential and the redox state of electron carriers. Furthermore, it could well reproduce flux inhibitor titration curves, which validates its global responses to local perturbations. This model is a solid basis for analyzing the role of OXPHOS and mitochondria in detail. They have been linked to various cellular processes like diabetes, cancer, mitochondrial disorders, but also to the production of reactive oxygen species, which are supposed to be involved in aging.
Taylor, Claire Louise. "Biochemical investigations of defects of the mitochondrial respiratory chain". Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.281706.
Texto completoLibros sobre el tema "Respiratory chain"
Pham, Nhu-An. Generation of oxidative stress by the respiratory chain following treatment with DNA damaging agents. Ottawa: National Library of Canada, 1999.
Buscar texto completoWainio, Walter. Mammalian Mitochondrial Respiratory Chain. Elsevier Science & Technology Books, 2012.
Buscar texto completoman, N. S. Gel. Bacterial Membranes and the Respiratory Chain. Springer, 2012.
Buscar texto completoBacterial Membranes and the Respiratory Chain. Springer, 2012.
Buscar texto completoman, N. S. Gel. Bacterial Membranes and the Respiratory Chain. Springer, 2012.
Buscar texto completoHargreaves, Iain P. Mitochondrial Respiratory Chain Disorders: From Clinical Presentation to Diagnosis and Treatment. Nova Science Publishers, Incorporated, 2019.
Buscar texto completoMerante, Frank. The molecular and biochemical characterization of human mitochondrial respiratory chain deficiencies. 1996.
Buscar texto completoMitochondrial Respiratory Chain Disorders: From Clinical Presentation to Diagnosis and Treatment. Nova Science Publishers, Incorporated, 2019.
Buscar texto completoThe molecular and biochemical characterization of the MLRQ subunit of NADH: Ubiquinone oxidoreductase in the human mitochondrial respiratory chain. Ottawa: National Library of Canada, 2001.
Buscar texto completoJou, J. Fay, Lori A. Aronson y Jacqueline W. Morillo-Delerme. Mitochondrial Disorder for Muscle Biopsy. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0049.
Texto completoCapítulos de libros sobre el tema "Respiratory chain"
Gooch, Jan W. "Respiratory Chain". En Encyclopedic Dictionary of Polymers, 920. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_14688.
Texto completoSkulachev, Vladimir P., Alexander V. Bogachev y Felix O. Kasparinsky. "The Respiratory Chain". En Principles of Bioenergetics, 87–118. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-33430-6_4.
Texto completoRitvo, Ariella Riva, Fred R. Volkmar, Karen M. Lionello-Denolf, Trina D. Spencer, James Todd, Nurit Yirmiya, Maya Yaari et al. "Respiratory Chain Disorders". En Encyclopedia of Autism Spectrum Disorders, 2572. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1698-3_101177.
Texto completoBien, Christian G., Christian E. Elger, Ali R. Afzal, Sirajedin Natah, Ritva Häyrinen-Immonen, Yrjö Konttinen, George S. Zubenko et al. "Respiratory Chain Disorders". En Encyclopedia of Molecular Mechanisms of Disease, 1834. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_6267.
Texto completoMunnich, A. "The Respiratory Chain". En Inborn Metabolic Diseases, 121–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-03147-6_10.
Texto completoAzzi, Angelo, Michele Müller y Néstor Labonia. "The Mitochondrial Respiratory Chain". En Organelles in Eukaryotic Cells, 1–8. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0545-3_1.
Texto completoSousa, Joana S., Edoardo D’Imprima y Janet Vonck. "Mitochondrial Respiratory Chain Complexes". En Subcellular Biochemistry, 167–227. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7757-9_7.
Texto completoMunnich, Arnold. "Defects of the Respiratory Chain". En Inborn Metabolic Diseases, 158–68. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-662-04285-4_13.
Texto completoDudkina, Natalya V., Egbert J. Boekema y Hans-Peter Braun. "Respiratory Chain Supercomplexes in Mitochondria". En The Structural Basis of Biological Energy Generation, 217–29. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-8742-0_12.
Texto completoMunnich, Arnold, Agnès Rötig y Marlène Rio. "Defects of the Respiratory Chain". En Inborn Metabolic Diseases, 223–38. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-15720-2_15.
Texto completoActas de conferencias sobre el tema "Respiratory chain"
Lapotko, Dmitry, Tat'yana Romanovskaya y Elena Gordiyko. "Photothermal monitoring of respiratory chain redox state in single live cells". En International Symposium on Biomedical Optics, editado por Manfred D. Kessler y Gerhard J. Mueller. SPIE, 2002. http://dx.doi.org/10.1117/12.469461.
Texto completoPETKOVIĆ, M., O. ZSCHÖRNIG, A. VOCKS, M. MÜLLER, J. SCHILLER, K. ARNOLD y J. ARNHOLD. "RESPIRATORY BURST RESPONSE OF HUMAN NEUTROPHILS TO EXOGENOUSLY ADDED LONG CHAIN PHOSPHATIDIC ACIDS". En Bioluminescence and Chemiluminescence - Progress and Current Applications - 12th International Symposium on Bioluminescence (BL) and Chemiluminescence (CL). WORLD SCIENTIFIC, 2002. http://dx.doi.org/10.1142/9789812776624_0065.
Texto completoDusek, Pavel, Marie Rodinova, Irena Liskova, Jiri Klempir, Jiri Zeman, Jan Roth y Hana Hansikova. "A37 Buccal respiratory chain complexes I and IV quantities in huntington’s disease patients". En EHDN 2018 Plenary Meeting, Vienna, Austria, Programme and Abstracts. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/jnnp-2018-ehdn.35.
Texto completoJaeger, V. K., D. Lebrecht, A. G. Nicholson, A. U. Wells, S. George, A. Gazdhar, M. Tamm, N. Venhoff, T. Geiser y U. A. Walker. "OP0090 Mitochondrial dna mutations and respiratory chain dysfunction in lung fibrosis of systemic sclerosis". En Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.2960.
Texto completoDomingue, Scott R., Adam J. Chicco, Randy A. Bartels y Jesse W. Wilson. "Pump-probe microscopy of respiratory chain pigments: towards non-fluorescent label-free metabolic imaging". En SPIE BiOS, editado por Ammasi Periasamy, Peter T. C. So, Karsten König y Xiaoliang S. Xie. SPIE, 2017. http://dx.doi.org/10.1117/12.2253378.
Texto completoSundar, Krishna M., Karl Ludwig, Jeffrey Stevenson y David B. Nielsen. "Implications Of Cytomegalovirus Detection By Polymerase-Chain Reaction In Respiratory Secretions Of Intubated Patients". En American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4712.
Texto completoBaburina, Yulia, Irina Odinokova, Roman Krestinin, Linda Sotnikova y Olga Krestinina. "INFLUENCE OF CHRONIC ALCOHOL DEPENDENCE ON CHANGES IN THE ACTIVITY OF RESPIRATORY CHAIN COMPLEXES". En XVIII INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2022. http://dx.doi.org/10.29003/m2684.sudak.ns2022-18/63-64.
Texto completoOnu, Charles C., Lara J. Kanbar, Wissam Shalish, Karen A. Brown, Guilherme M. Sant'Anna, Robert E. Kearney y Doina Precup. "A semi-Markov chain approach to modeling respiratory patterns prior to extubation in preterm infants". En 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2017. http://dx.doi.org/10.1109/embc.2017.8037249.
Texto completoKonokhova, Yana, Martin Picard, Gilles Gouspillou, Sophia Kapchinsky, Jacinthe Baril, Thomas Jagoe y Tanja Taivassalo. "Prevalence Of Mitochondrial Respiratory Chain Deficiency In Skeletal Muscle Of Chronic Obstructive Pulmonary Disease Patients". En American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5320.
Texto completoFeize, L., D. Minai-Tehrani, B. Behboudi y E. Keyhani. "Identification of the respiratory chain of Armillaria mellea (A.m.) in mushroom state and cultured in vitro". En Proceedings of the II International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2007). WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789812837554_0014.
Texto completoInformes sobre el tema "Respiratory chain"
Terry Ann Krulwich. The Respiratory Chain of Alkaliphilic Bacteria. Office of Scientific and Technical Information (OSTI), enero de 2008. http://dx.doi.org/10.2172/922628.
Texto completoGelb, Jr., Jack, Yoram Weisman, Brian Ladman y Rosie Meir. Identification of Avian Infectious Brochitis Virus Variant Serotypes and Subtypes by PCR Product Cycle Sequencing for the Rational Selection of Effective Vaccines. United States Department of Agriculture, diciembre de 2003. http://dx.doi.org/10.32747/2003.7586470.bard.
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