Tesis sobre el tema "Puberty"
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Bovard, Joshua Maschio. "Does competitive swimming during puberty affect lung development in pubertal females?" Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/62896.
Texto completoEducation, Faculty of
Kinesiology, School of
Graduate
Cohen, Robin Zoe. "Puberty and scizophrenia". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0003/MQ40801.pdf.
Texto completoJeffreys, Renee M. Ph D. "Physical Activity and Pubertal Onset: Longitudinal Analysis of the Puberty Study Cohorts". University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406820304.
Texto completoLee, Bo Yeon. "Action of manganese on puberty". Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/5871.
Texto completoBalzer, Ben William Robert. "NOVEL WAYS OF ASSESSING PUBERTY". Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21771.
Texto completoKim, Kenneth. "Family structure, puberty and reproductive development". Thesis, University of Sheffield, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266838.
Texto completoMobley, Stacey Lloyd. "Calcium kinetics in girls during puberty /". The Ohio State University, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=osu1488191667183775.
Texto completoPaczkowski, Melissa Jeanne. "Effects of experimental fascioliasis on puberty and comparison of mounting activity by radiotelemetry in pubertal and gestating beef heifers". Texas A&M University, 2004. http://hdl.handle.net/1969.1/2796.
Texto completoPatterson, Jennifer Lynne. "Factors influencing onset of puberty in gilts". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ60485.pdf.
Texto completoBridges, Nicola Anne. "The endocrine and physical events of puberty". Thesis, University of Southampton, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295696.
Texto completoMaquivar, Martin G. "Nutritional Regulation of Precocious Puberty in Heifers". The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1322586535.
Texto completoHess, Monna Fay. "Steroidogenesis in the equine testis throughout puberty /". For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2003. http://uclibs.org/PID/11984.
Texto completoRubio, Abadal Elena. "Factors del neuro-desenvolupament i de la pubertat que es relacionen amb l'edat d'inicide primers episodis de psicosi". Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/397730.
Texto completoIntroduction: Previous studies have shown that age at onset of psychosis (AOP) is associated with higher clinical and functional severity and worse prognosis. An in-depth study of AOP can contribute to the improvement of knowledge of psychosis pathogenesis and help improve its early and specific treatment. There are several genetic and environmental factors that have been related to AOP variations such as age of puberty, obstetric complications, family history or substance use. Objectives: The purpose of this project is to study how these factors relate to AOP in a sample of patients with a first episode of psychosis. The objective of the first study is to relate, in the women subsample, the age of menarche, as a measure of puberty, with AOP, and to study the relationship between age of menarche and clinical severity and prognosis. In the second study, the objective is to determine the relationship between AOP and history of obstetric complications, low birth weight and preterm birth and to evaluate how family history of psychosis and age of parents relate to AOP. Methods: Patients included in the the study were aged between 10 and 65 years old, with a first psychotic episode, both recruited in community and hospital facilities, and belonging to adults or children and adolescent mental health services. The final sample was of 90 patients. For this study a socio-demographic questionnaire was designed, completed through clinical interview, and the following scales were administered: PANSS (Positive and Negative Syndrome Scale) ICG-ESQ (Clinical Global Impression - Schizophrenia Scale), GAF (Global Assessment of Functioning) sv-DAS (Disability Assessment Schedule short version), Wechsler Intelligence scale and EuroQol 5D quality of life scale. We obtained the decimal ages of onset of psychotic symptoms, of first contact with psychiatry and of first admission to a psychiatric hospital, if that was the case. Age of menarche was obtained retrospectively. Through clinical interview and the questionnaire designed for the study, ages of the father and the mother at time of child birth and substance use prior to the psychosis onset (DSM-IV abuse and dependence criteria) were also obtained. The history of psychosis in the mother or father was collected following the Andreasen model and obstetric antecedents using the scale of Lewis and Murray obstetric complications. Also weight and gestational age of the patient at time of birth were collected, and whether the mother had experienced previous miscarriages or had used any substances during pregnancy. Results: A significant correlation between age of menarche and AOP, PANSS scale, ICG-ESQ, GAF, total DAS or EuroQol was not found. Pre-eclampsia, need of incubator at birth, use of forceps, paternal history of psychosis and low birth weight, were associated with an earlier AOP. Use of forceps and birth weight were the variables that best predicted AOP. Conclusions: The results suggest a greater complexity of estrogen hypothesis, involving other factors such as biological and psychosocial ones, and highlight the role of the prenatal period in the development of psychosis and the importance of adequately monitor pregnancy and delivery, especially in cases of parents with a history of psychosis. Risk factors such as genetic and family burden, pregnancy and childbirth complications and the use of substances during adolescence could be used effectively to predict psychotic disorders.
Evuarherhe, Obaro. "Gender, puberty and the hypothalamic-pituitary-adrenal axis". Thesis, University of Bristol, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618813.
Texto completoBaxter-Jones, A. D. G. "Physical effects of training during puberty and adolescence". Thesis, University of Aberdeen, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261591.
Texto completoHoward, Sasha. "Investigation of the genetic regulation of delayed puberty". Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/28165.
Texto completoGoddings, A. M. "The impact of puberty on adolescent brain development". Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1468921/.
Texto completoHoughton, Lauren Claire. "Juvenility, puberty and adolescence among Bangladeshi and British youth". Thesis, Durham University, 2013. http://etheses.dur.ac.uk/6958/.
Texto completoCho, Yoon Hi. "AUTONOMIC DYSFUNCTION, OBESITY AND PUBERTY IN TYPE 1 DIABETES". Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/16471.
Texto completoVetter, Nora C., Mandy Drauschke, Juliane Thieme y Mareike Altgassen. "Adolescent Basic Facial Emotion Recognition Is Not Influenced by Puberty or Own-Age Bias". Frontiers Research Foundation, 2018. https://tud.qucosa.de/id/qucosa%3A31831.
Texto completoLargier, Damian Douglas Christopher. "Pubertal development in urban Xhosa schoolgirls". Master's thesis, University of Cape Town, 1995. http://hdl.handle.net/11427/26625.
Texto completoGasser, Chad L. "Ovarian and endocrine dynamics associated with sexual maturation in beef heifers and the influence of diet, weaning age, and other factors during early reproductive development". The Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=osu1122295880.
Texto completoJeffery, Alison Norah. "The impact of puberty on insulin resistance-a longitudinal study". Thesis, Exeter and Plymouth Peninsula Medical School, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530386.
Texto completoCharmandari, Evangelia. "Congenital adrenal hyperplasia : the influence of puberty on cortisol pharmacokinetics". Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395379.
Texto completoSumbung, Frederick Patta. "Ovarian function and response in prepubertal ewes through to puberty". Thesis, Sumbung, Frederick Patta (1985) Ovarian function and response in prepubertal ewes through to puberty. PhD thesis, Murdoch University, 1985. https://researchrepository.murdoch.edu.au/id/eprint/53694/.
Texto completoAkyol, Pınar Dündar Bumin Nuri. "Isparta'daki kız çocuklarında ortalama puberte ve menarş başlama yaşlarının saptanması ve menarş başlama yaşını etkileyen faktörler ile menstrüal siklus özelliklerinin belirlenmesi /". Isparta : SDÜ Tıp Fakültesi, 2006. http://tez.sdu.edu.tr/Tezler/TT00297.pdf.
Texto completoBalzer, Ben. "NOVEL WAYS OF ASSESSING PUBERTY Findings from the Adolescent Rural Cohort Study of Hormones, Health, Education, Environments and Relationships". Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21682.
Texto completoTimmons, Brian Weldon Bar-Or Oded. "Immunological changes in response to acute exercise, considering puberty and sex /". *McMaster only, 2005.
Buscar texto completoFallah-Rad, Amir Hooshang. "Interrelation between thyroid hormones and onset of puberty in ram lambs". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ31977.pdf.
Texto completoTakahashi, Melanie L. "Adolescence and identity transformation, a cross-cultural analysis of puberty initiations". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ36851.pdf.
Texto completoAndersson, Håkan. "Photoperiodism in pigs : studies on timing of male puberty and melatonin /". Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2000. http://epsilon.slu.se/v90.pdf.
Texto completoCubitt, Tania Anne. "Environmental factors, pasture composition, growth rate and puberty in growing Thoroughbreds". Thesis, Virginia Tech, 2004. http://hdl.handle.net/10919/31576.
Texto completoMaster of Science
Tregaskes, Lisa D. "Performance testing Simmental heifers : the effects on puberty and superovulatory response". Thesis, University of Aberdeen, 1994. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU066541.
Texto completoSpjuth, Linda. "Di(2-ethylhexyl) phthalate and semen quality in boars : effects of pre-pubertal oral exposure on sperm production, viability and function post-puberty /". Uppsala : Dept. of Clinical Sciences, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/2006104.pdf.
Texto completoGasser, Chad Lamar. "Ovarian and endocrine dynamics associated with sexual maturation in beef heifers and the influence of diet, weaning age, and other factors during early reproductive development". Connect to this title online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1122295880.
Texto completoTitle from first page of PDF file. Document formatted into pages; contains xvii, 181 p. : ill. Includes bibliographical references (p. 159-181). Available online via OhioLINK's ETD Center
Silva, Denise Salioni da [UNESP]. "Puberdade retardada no rato macho: correlações entre indicadores externos e internos e repercussões sobre a qualidade espermática e fertilidade". Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/87768.
Texto completoA puberdade constitui um período de rápidas e interativas alterações morfológicas, endócrinas e comportamentais. Atualmente a exposição à contaminantes ambientais tem sido implicada como um dos fatores responsáveis por alterações no desenvolvimento infantil, resultando em precocidade ou atraso na puberdade. Numerosos compostos químicos de uso doméstico, industrial e agrícola possuem comprovada atividade hormonal, sendo conhecidos com desreguladores endócrinos. Alguns clínicos estão começando a avaliar alguns parâmetros relacionados à interferência desses compostos no desenvolvimento de crianças residentes em áreas contaminadas, mas não há estudos correlacionando o atraso na puberdade masculina com possíveis alterações do trato reprodutivo e fertilidade a partir da maturidade sexual. Esse estudo objetivou investigar se o retardo na instalação da puberdade masculina compromete parâmetros reprodutivos na puberdade e as possíveis repercussões na fertilidade na vida adulta, utilizando o rato como modelo experimental. Tendo em vista ainda que na literatura existe um grande intervalo fixado para o início da puberdade, o trabalho pretendeu também analisar os parâmetros de puberdade do rato normal, contribuindo para o estabelecimento de uma idade real para a puberdade de ratos machos Wistar. Para tanto, foi provocado um atraso no início da puberdade mediante administração de dose alta de dibutil ftalato (DBP) durante o período fetal. Foram avaliados parâmetros morfofuncionais do trato reprodutivo masculino, dosagens hormonais, avaliações espermáticas, além de análises histopatológicas e morfométricas do testículo e epidídimo. Na puberdade, houve diminuição significativa do peso da próstata dos animais expostos ao DBP, além de redução da produção diária de espermatozóides...
Puberty is a period of fast and interactive morphological, endocrine and behavioral changes. Currently, the exposure to environmental contaminants is considered one of the factors responsible for alterations in child development, resulting in pubertal precocity or delay. Many chemical compounds with domestic, industrial and agricultural use, known as endocrine disruptors, have shown hormonal activity. Some clinicians are beginning to evaluate some parameters related to the interference of these compounds in the development of children living in contaminated areas, but there are no studies correlating this delay on puberty with possible changes in the reproductive tract and fertility from sexual maturity. This study aimed to investigate whether a delay in puberty installation affects reproductive parameters in pubertal and adult male rats. Especially considering that the literature shows a wide range fixed for the beginning of puberty, the study also intended to analyze the parameters of puberty in normal rats, contributing to the establishment of an actual age for puberty in male Wistar rats. The onset of puberty was delayed through administration of a high doses of dibutyl phthalate (DBP) during the fetal period. We assessed morphofunctional parameters of the male reproductive tract, hormonal levels, sperm evaluations, and histopathologic and morphometric analysis of testis and epididymis. At puberty, the prostate weight of DBP-exposed animals was significantly reduced. The daily sperm production was reduced in the testis of the pubertal DBP-exposed rats, and this alteration remained in the adult rats. However, neither sperm morphology nor sperm motility was altered, as well as the capacity of fertilization assessed by AI. The histopathology of testis revealed a high number of tubules with... (Complete abstract click electronic access below)
Westling, Erika Helen. "Timing of pubertal maturation and substance use gender differences in family, peer, and individual difference factors /". Diss., Restricted to subscribing institutions, 2007. http://proquest.umi.com/pqdweb?did=1495962311&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Texto completoLeppik, Aire. "Changes in anthropometry, somatotype and body composition during puberty : a longitudinal study /". Online version, 2005. http://dspace.utlib.ee/dspace/bitstream/10062/520/5/leppik.pdf.
Texto completoMartinez, Chavez Carlos Cristian. "Photic Entrainment and onset of puberty in Nile tilapia Oreochromis niloticus niloticus". Thesis, University of Stirling, 2008. http://hdl.handle.net/1893/354.
Texto completoEmerson, Sam R. "Changes in expiratory flow limitation during exercise from pre- to post-puberty". Thesis, Kansas State University, 2014. http://hdl.handle.net/2097/17376.
Texto completoDepartment of Kinesiology
Craig A. Harms
Expiratory flow limitation (EFL) during exercise can limit exercise tolerance. We have recently reported a high prevalence of EFL independent of sex in prepubescent children (Swain et al. 2010) that greatly exceeds that reported in adults. It is unknown how maturation and growth from pre- to post-puberty affects pulmonary function, specifically EFL, during exercise. The purpose of this longitudinal study was to investigate the changes in cardiopulmonary function from pre- to post-puberty in boys and girls. We hypothesized that EFL prevalence would decrease from pre- to post-puberty (with boys exhibiting a greater decrease than girls) and that the decrement could be explained by an increase in pulmonary function and a decrease in VE/VCO2. Twenty-one children (ages 12-16 yrs; 11 boys, 10 girls) were recruited from 40 prepubescent children who completed testing in our laboratory ~5 years ago. Subjects completed pulmonary function tests before and after an incremental exercise test to exhaustion (VO2max) on a cycle ergometer. EFL was determined using the percent tidal volume (VT) overlap method. Nineteen of the 21 subjects (10 boys, 9 girls; 90%) exhibited EFL pre-puberty, while only 7 of the 21 subjects (5 boys, 2 girls; 33%) exhibited EFL post-puberty. Of the subjects who experienced EFL post-puberty, all had experienced EFL pre-puberty. Boys had a significantly greater vital capacity (VC) than girls both pre- (~15%) and post-puberty (B: 4.73 ± 0.53; G: 3.80 ± 0.29 L). Maximal aerobic capacity (VO2max) significantly increased (~110% in girls and ~120% in boys) from pre- to post-puberty and was greater (p<0.05) in boys post-puberty (B: 2.76 ± 0.43; G: 1.94 ± 0.35 L/min). VE/VCO2 also significantly decreased (~13%) in both boys and girls. Post-puberty subjects regulated tidal breathing at higher lung volumes (greater ERV/FVC and lower IRV/FVC) during exercise compared to pre-puberty. None of the subjects experienced significant arterial desaturation pre-puberty or post-puberty. Our findings suggest that the prevalence of EFL declines as children mature from pre- to post-puberty, likely due to increases in lung size, decreases in VE/VCO2, and/or changes in breathing mechanics that are greater than increases in maximal ventilation that occur with increased pulmonary gas exchange.
Anderson, Leslie H. "Maturation of hypothalamic centers associated with the onset of puberty in heifers /". The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu148793557377098.
Texto completoJoshi, Rupali Narayan. "IDENTIFICATION OF MECHANISMS OF DELAYED PUBERTY ON BONE STRENGTH DEFICITS DURING DEVELOPMENT". Diss., Temple University Libraries, 2010. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/55431.
Texto completoPh.D.
Osteoporosis which is frequently referred to as a pediatric disease with geriatric consequences (Golden, 2000) can result from a lack of optimal bone accrual during the development (NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy, 2001). Pubertal timing is a key factor that contributes to optimal bone accrual and strength (Bonjour et al., 1994; 21 Warren et al., 2002). Bone mass doubles during the onset of puberty and young adulthood (Katzman et al., 1991) with more than 90% of peak bone mass being accrued at the end of second decade of life (Schneider & Wade, 2000). The rate of periosteal expansion is elevated during the pubertal period (Specker et al., 1987; Bradney et al., 2000) and this expansion parallels longitudinal growth (Parfitt, 1994). Irrespective of other changes, periosteal expansion lowers fracture risk by improving the strength of long bones by increasing the moment of inertia (Orwoll, 2003). Therefore, a delay in puberty may actually increase the time available for periosteal development and positively affect bone strength. Previous animal studies have shown decreases in strength, endocortical bone formation and increases in periosteal bone formation with delayed puberty. Clinical studies report negative effects of delayed puberty on bone mass accrual suggesting that delayed puberty is a multifactorial problem affecting bone strength development. The purpose of this study was to determine the effect of delayed puberty on mechanical strength and endocortical bone marrow cells in two models: female rats treated with gonadatropin releasing hormone antagonists (GnRH-a) and energy restriction (30%). Thirty-two female Sprague Dawley rats (21 to 22 days-of-age) were received from (Charles Rivers Laboratories, Wilmington, MA, USA) and housed individually at the Temple University Central Animal Facility (Temple University Weiss Hall). Animals were randomly assigned to one of three groups; control (n=10), GnRH-a (n=10) and energy restriction (ER) (n=12). The GnRH-a group was injected with gonadotropin releasing antagonist injections (GnRH-a) (Antide, Bachem, Torrance, Ca. USA) at a dose of 2.5 mg/kg/BW. The ER group received a 30% energy restricted diet (0pen Source diet (D07100606)(Research Diets, New Brunswick, NJ). All animals were sacrificed on Day 51. One way analysis of variance testing (ANOVA) with a significance level of 0.05 was used to assess group differences. Following the two protocols the uterine weight in the GnRH-a group was 80.6% lower than control; no change in the ER group. Ovarian weight was significantly lower in the GnRH-a group (83.3%) and in the ER group (33.3%) as compared to controls. A 22.7% lower muscle weight was found in the ER group but was equal to control and GnRH-a when normalized by body weight (BW). The retro-peritoneal fat pad weight was significantly decreased by 64.95% in the ER group as compared to controls. Energy restriction did not result in any deficit in bone strength when normalized by body weight however the GnRH-a group had a 26.2% lower bone strength compared to control. Histomorphometric changes were not significantly different between groups, but the ratio for periosteal versus endocortical bone formation rates for the control group was 1.38, GnRH-a was significantly higher with a ratio of 5.54 and for ER was 3.02 indicating that periosteal BFR are almost twice endocortical BFR in the experimental groups. There was a significant decrease in the trabecular percent bone volume (BV/TV) of the lumbar vertebra in the GnRH-a group (20.2%) compared to control. However BV/TV was significantly higher in the ER (18.4%) compared to the control group. Proliferation was suppressed to 59.6% of control in the GnRH-a group but only 85.5% of control in the ER group. The alkaline phosphatase activity was 31.2% lower in the GnRH-a group and 63.9% lower in the ER group. The relative quantification (RQ) of RUNX2 gene expression was lowest in control followed by GnRH-a and highest in ER group although no statistical significance was observed between any groups. Thus our data infers that 30% energy restriction does not negatively impact bone health. Thirty percent food restriction with no deficits in micronutrients or hormone suppression may just suppress growth as indicated by the maintenance of bone strength per body weight and equivalent muscle mass per body weight in the ER group compared to control. The GnRH-a injections resulted in decreased bone strength and trabecular bone volume. Female Athlete Triad or Anorexia Nervosa are the two clinical conditions hypothesized to result from a combination of ER and estrogen deficient environment. Studies replacing estrogen in hypothalamic amenorrhea or IGF-1 in anorexia alone have failed to improve bone mineral density (BMD), but a combination of IGF-1 and estrogen has been successful in improving BMD. This suggests that estrogen dependant and independent mechanisms work in combination to protect bone. Our study investigated both mechanisms separately and indicates that ER at 30% may be protective for bone health. Since estrogen deficiency may be the extreme end of the spectrum affecting trabecular bone, treatment therapies may have to be based on age, magnitude and severity of energy restriction and presence or absence of menstrual status.
Temple University--Theses
Seigenfuse, Matthew David. "Low Estrogen Model and Percent Lamellar Bone Pre and Post Puberty [thesis]". Master's thesis, Temple University Libraries, 2010. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/94126.
Texto completoM.S.
INTRODUCTION: Pubertal growth is an important time during development for bone accrual and attainment of peak bone mass. Suboptimal bone gain has been observed in females with reproductive abnormalities such as primary and secondary amenorrhea and these conditions are very prevalent in female athletes. Amenorrhea is associated with decreased estradiol levels. Previous research has shown that in prepubertal animals a low estrogen environment significantly decreased mechanical strength, but there was no significant loss in bone area and actually an increase in moment of inertia. The decrease in mechanical properties may be related to the microstructure of the bone. Two types of bone are involved in growth-- woven bone, which is added for structural support in the short term, and lamellar bone , which is highly organized and has a greater contribution to overall strength. We will test the hypotheses that suppressed estradiol will result in bones with no change in cortical area and decreased strength properties but will have a larger composition of non lamellar bone as opposed to lamellar bone. PURPOSE: The goal of this study was to determine the relative amounts of woven and lamellar tissue in a bone and the relationship with the bone's mechanical strength in two models of low estrogen-- pre- and post-pubertal onset. METHODS: Fifty-Five female Sprague-Dawley rats were randomly assigned into four groups: a control group (n=14) and three experimental groups injected with gonadotropin releasing-hormone antagonist (GnRH-a)-- the Dose 1 group was injected with 1.25 mg/kg/dose daily (n=14), the Dose 2 was injected with 2.5 mg/kg/dose daily (n=14), and the Dose 3 group was injected with 5.0 mg/kg/dose, 5 days per week (n=13). All groups were sacrificed at Day 49. Additionally, twenty-nine Sprague Dawley rats were randomly assigned into three groups. The baseline day 65 group (BL 65) was sacrificed on day 65 (n=9). There was an aged match control group that was sacrificed on day 90 (n=12). Finally, there was an AMEN experiment group injected with 2.5 mg/kg/dose daily that was sacrificed on day 90 (n=9). All experimental groups for both protocols received injections of gonadotropin releasing hormone antagonists (GnRH-a) (Zentaris GmbH) intraperitoneally. Left femora were mechanically tested under 3-point bending. The right femora were dehydrated, embedded in polymethylmethacrylate, cut and ground to 100 µm thickness. Bones were analyzed under polarized light using Stereo Investigator Software (MBF Bioscience, VT). The proportion of the cortex with primary lamellar vs. non-lamellar/other primary tissue type was measured and expressed as percent of the total cortical bone area. Outcome measures included lamellar endocortical area, lamellar periosteal area, cortical area, endocortical area, % lamellar area and % non-lamellar area. RESULTS: There was a significant decrease (p<.05) in the distribution of lamellar versus non-lamellar cortical tissue type in the experimental group in the model of delayed puberty. Additionally, the pre-pubertal bones had a lower percentage of lamellar periosteal and endocortical area. The post-pubertal group showed no significant differences between the control and experimental group in any of the outcome measures. CONCLUSION: There were significant differences in relative bone distribution throughout the femoral cortex. Relative decreases in lamellar tissue distribution, especially on the periosteal surface, will result in decreased mechanical strength due to increased percentage of woven bone in pre-pubertal models.
Temple University--Theses
Murray, Emma. "Immune Challenge During Puberty: Role of the Gut Microbiota and Neurobehavioural Outcomes". Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/40467.
Texto completoMechaly, Alejandro S. "Neuroendocrine control of puberty in vertebrates : characteriization of the kisspeptin system in flatfish". Doctoral thesis, Universitat Pompeu Fabra, 2011. http://hdl.handle.net/10803/38523.
Texto completoEl recentment descobert decapèptid kisspeptina i el seu receptor associat a una proteïna G formen un sistema que s’expressa ubiqüitament i que està implicat en diverses funcions, moltes de les quals encara no estan ben caracteritzades. En el cervell, la kisspeptina és secretada per neurones específiques, mentre que el seu receptor es troba a les neurones GnRH. Aquest sistema s’ha relacionat amb el control de l’inici de la pubertat en diferents vertebrats, des de peixos fins a mamífers. En aquest estudi, hem caracteritzat el gen de la kisspeptina en el llenguado senegalès, i els gens del receptor de la kisspeptina tant a llenguado senegalès com en l’Halibut de l’Atlàntic. Al contrari del que ocorre en moltes altres espècies de peixos, aquestes dues espècies només presenten un gen pel lligand i un gen pel recep- tor. Aquest fet és probable que estigui relacionat amb la reducció de la mida del genoma que han sofert els Pleuronectiformes. Tot i així, en les dues espècies s’hi troba un mecanisme d’empalmament alternatiu conseqüència d’una retenció intrónica que produeix una isoforma no funcional. Ara bé, si aquest mecanisme està relacionat amb el control de l’abundància dels trànscrits de la isoforma funcional encara està per esbrinar. Per altra banda, hem trobat canvis en l’expressió gènica tant en l’espai com en el temps durant un cicle reproductiu dels gens de la kisspeptina i el seu receptor en el cervell, pituïtària i gònades. Finalment, també presentem la primera evidència, en un vertebrat no mamífer, d’una possible relació entre el balanç energètic i la reproducció controlada pel sistema kisspeptina.
Al-Khamees, Sami A. "Photoperiod effects on circadian rhythms and puberty onset in African catfish Clarias gariepinus". Thesis, University of Stirling, 2009. http://hdl.handle.net/1893/1819.
Texto completoChandarana, N. y N. K. Bogutska. "Gender-specific peculiarities of the bronchial asthma phenotypes in children after puberty onset". Thesis, .Матеріали ІV Міжнародного медико-фармацевтичного конгресу студентів і молодих учених [«Пріоритети і перспективи молодіжної науки»] BIMCO, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/13164.
Texto completoMohamed, Abdullahi Abdulkadir y N. K. Bogutska. "Transition of the bronchial asthma phenotypes in females from pre- to post-puberty". Thesis, Матеріали ІV Міжнародного медико-фармацевтичного конгресу студентів і молодих учених [«Пріоритети і перспективи молодіжної науки»] BIMCO, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/13170.
Texto completoNirbhay, Chandarana y N. K. Bogutska. "Gender-specific differences in children with bronchial asthma before and after puberty onset". Thesis, Fundamental Science and Clinical Medicine: Abstract Book of 20th International Medical Biological Conference of Young Researchers. St. Petersburg, 2017, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/13186.
Texto completoZhu, Jia. "A Shared Genetic Basis for Self-Limited Delayed Puberty and Idiopathic Hypogonadotropic Hypogonadism". Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:15821591.
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